あなたは歯科・医療関係者ですか？

WHITE CROSSは、歯科・医療現場で働く方を対象に、良質な歯科医療情報の提供を目的とした会員制サイトです。

日本語AIでPubMedを検索

歯科医師情報サイトTOP / PubMed論文検索

日本語AIでPubMedを検索

PubMedの提供する医学論文データベースを日本語で検索できます。AI(Deep Learning)を活用した機械翻訳エンジンにより、精度高く日本語へ翻訳された論文をご参照いただけます。
対象期間    ～ 

2020年07月 みんなが読んでいる論文

Ca依存性NOX5（NADPHオキシダーゼ5）は活性酸素生成を介して心肥大を誇張する

Ca-Dependent NOX5 (NADPH Oxidase 5) Exaggerates Cardiac Hypertrophy Through Reactive Oxygen Species Production.
  • Guo-Jun Zhao
  • Chang-Ling Zhao
  • Shan Ouyang
  • Ke-Qiong Deng
  • Lihua Zhu
  • Augusto C Montezano
  • Changjiang Zhang
  • Fengjiao Hu
  • Xue-Yong Zhu
  • Song Tian
  • Xiaolan Liu
  • Yan-Xiao Ji
  • Peng Zhang
  • Xiao-Jing Zhang
  • Zhi-Gang She
  • Rhian M Touyz
  • Hongliang Li
  • Hypertension.2020 Jul;:HYPERTENSIONAHA12015558. doi: 10.1161/HYPERTENSIONAHA.120.15558.Epub 2020-07-20.

NOX2 shRNAの標的的発現による酸化的損傷の減衰は、イヌ心房における電気的リモデリングの発症と維持を抑制する。心房細動に対する新規遺伝子治療アプローチ

Attenuation of Oxidative Injury with Targeted Expression of NOX2 shRNA Prevents Onset and Maintenance of Electrical Remodeling in the Canine Atrium: A Novel Gene Therapy Approach to Atrial Fibrillation.
  • Shin Yoo
  • Anna Pfenniger
  • Jacob Hoffman
  • Wenwei Zhang
  • Jason Ng
  • Amy Burrell
  • David A Johnson
  • Georg Gussak
  • Trent Waugh
  • Suzanne Bull
  • Brandon Benefield
  • Bradley P Knight
  • Rod Passman
  • J Andrew Wasserstrom
  • Gary L Aistrup
  • Rishi Arora
  • Circulation.2020 Jul;doi: 10.1161/CIRCULATIONAHA.119.044127.Epub 2020-07-20.

プロスタグランジンFの経膣内投与は、泌乳中の乳牛の黄体退縮の誘導に筋肉内注射と同等の効果がありました

Intravaginal instillation of prostaglandin F was as effective as intramuscular injection for induction of luteal regression in lactating dairy cows.
  • M Masello
  • M Scarbolo
  • M V Schneck
  • M M Perez
  • E M Schillkowsky
  • E M Sitko
  • F Sosa Hernandez
  • E M Cabrera
  • R M Rossi
  • J O Giordano
  • J. Dairy Sci..2020 Mar;103(3):2743-2755. S0022-0302(19)31133-6. doi: 10.3168/jds.2019-17589.Epub 2019-12-25.

真核細胞／真核生物／核生物の基本用語の使用について、アスガルド古細菌における真核生物のシグネチャーの発見による進化論的見解について、真核生物の新しい分類群名について

On the use of basic terms eukaryotic cell/eukaryotes/nucleated organisms, on evolutionary views challenged by the discovery of eukaryotic signatures in asgard archaea, and on a new taxon name for eukaryotes.
  • Alexander V Pinevich
  • BioSystems.2020 Jun;:104178. S0303-2647(20)30077-0. doi: 10.1016/j.biosystems.2020.104178.Epub 2020-06-10.

術前のX線写真は、以前の肩関節形成術後の再手術における術中の課題を予測するのに役立つか？

Do preoperative radiographs help predict intraoperative challenges in revision surgery after previous shoulder hemiarthroplasty?
  • David E O'Briain
  • Peter Simon
  • Kaitlyn N Christmas
  • Miguel A Diaz
  • A Vincent Hess
  • Eric G Hernandez-Ortiz
  • Thomas Sellers
  • Paul B McLendon
  • Mark A Mighell
  • Mark A Frankle
  • J Shoulder Elbow Surg.2019 Jun;28(6S):S161-S167. S1058-2746(19)30263-0. doi: 10.1016/j.jse.2019.04.013.

分娩中の女性におけるQ熱の血清有病率：レユニオン島におけるEQRUN横断研究

Q fever seroprevalence in parturient women: the EQRUN cross-sectional study on Reunion Island.
  • Julien Jaubert
  • Laura Atiana
  • Sophie Larrieu
  • Philippe De Vos
  • Claudine Somon-Payet
  • Sylvaine Porcherat
  • Yoan Mboussou
  • Florence Naze
  • Sandrine Picot
  • Malik Boukerrou
  • Pierre-Yves Robillard
  • Patrick Gérardin
  • BMC Infect. Dis..2020 Apr;20(1):261. 10.1186/s12879-020-04969-w. doi: 10.1186/s12879-020-04969-w.Epub 2020-04-03.

免疫情報学ツールを用いたより良いエピトープ発見、精密な免疫工学、ワクチン設計の高速化

Better Epitope Discovery, Precision Immune Engineering, and Accelerated Vaccine Design Using Immunoinformatics Tools.
  • Anne S De Groot
  • Leonard Moise
  • Frances Terry
  • Andres H Gutierrez
  • Pooja Hindocha
  • Guilhem Richard
  • Daniel Fredric Hoft
  • Ted M Ross
  • Amy R Noe
  • Yoshimasa Takahashi
  • Vinayaka Kotraiah
  • Sarah E Silk
  • Carolyn M Nielsen
  • Angela M Minassian
  • Rebecca Ashfield
  • Matt Ardito
  • Simon J Draper
  • William D Martin
  • Front Immunol.2020;11:442. doi: 10.3389/fimmu.2020.00442.Epub 2020-04-07.

CalliSpheres® microspheres (CSM) 薬剤溶出ビーズによる動脈間化学塞栓療法と従来の動脈間化学塞栓療法が肝細胞癌患者の治療効果と生存率に及ぼす包括的な予測因子

Comprehensive predictive factors for CalliSpheres® microspheres (CSM) drug-eluting bead-transarterial chemoembolization and conventional transarterial chemoembolization on treatment response and survival in hepatocellular carcinoma patients.
  • Changyong Chen
  • Huaiming Qiu
  • Yuanhui Yao
  • Zishu Zhang
  • Cong Ma
  • Yilong Ma
  • Chang Zhao
  • Hua Xiang
  • Hui Zhao
  • Chuansheng Zheng
  • Bin Xiong
  • Haiping Li
  • Qingyun Long
  • Jun Zhou
  • Chao Luo
  • Hongyao Hu
  • Clin Res Hepatol Gastroenterol.2020 Jun;S2210-7401(20)30153-4. doi: 10.1016/j.clinre.2020.05.008.Epub 2020-06-24.

Revision of a Failed Latissimus Dorsi Transfer for aMassive Rotator Cuff Tear With Arthroscopic Anatomic Bridging Reconstruction Using an Acellular Human Dermal Matrix Allograft

Revision of a Failed Latissimus Dorsi Transfer for a Massive Rotator Cuff Tear With Arthroscopic Anatomic Bridging Reconstruction Using an Acellular Human Dermal Matrix Allograft.
  • Rakesh John
  • Catherine M Coady
  • Ivan Wong
  • Arthrosc Tech.2019 Oct;8(10):e1171-e1179. S2212-6287(19)30125-2. doi: 10.1016/j.eats.2019.06.007.Epub 2019-09-19.

筋富化ロングノンコーディングRNA H19を標的とすると、病的な心肥大が逆転する

Targeting muscle-enriched long non-coding RNA H19 reverses pathological cardiac hypertrophy.
  • Janika Viereck
  • Anne Bührke
  • Ariana Foinquinos
  • Shambhabi Chatterjee
  • Jan A Kleeberger
  • Ke Xiao
  • Heike Janssen-Peters
  • Sandor Batkai
  • Deepak Ramanujam
  • Theresia Kraft
  • Serghei Cebotari
  • Faikah Gueler
  • Andreas M Beyer
  • Jessica Schmitz
  • Jan H Bräsen
  • Jan D Schmitto
  • Mariann Gyöngyösi
  • Alexandra Löser
  • Marc N Hirt
  • Thomas Eschenhagen
  • Stefan Engelhardt
  • Christian Bär
  • Thomas Thum
  • Eur. Heart J..2020 Jul;ehaa519. doi: 10.1093/eurheartj/ehaa519.Epub 2020-07-13.

SARS-CoV-2 の検出のための自動分析を備えたワンステップ、ワンチューブのリアルタイム RT-PCR ベースのアッセイ

A one-step, one-tube real-time RT-PCR based assay with an automated analysis for detection of SARS-CoV-2.
  • Bhasker Dharavath
  • Neelima Yadav
  • Sanket Desai
  • Roma Sunder
  • Rohit Mishra
  • Madhura Ketkar
  • Prasanna Bhanshe
  • Anurodh Gupta
  • Archana Kumari Redhu
  • Nikhil Patkar
  • Shilpee Dutt
  • Sudeep Gupta
  • Amit Dutt
  • Heliyon.2020 Jul;6(7):e04405. S2405-8440(20)31249-4. doi: 10.1016/j.heliyon.2020.e04405.Epub 2020-07-07.

特異的なPKC-α阻害剤であるキレリスリンは、コストゥノリド誘導性紅斑を抑制する

The specific PKC-α inhibitor chelerythrine blunts costunolide-induced eryptosis.
  • Mehrdad Ghashghaeinia
  • Pavla Koralkova
  • Daniela Giustarini
  • Renata Mojzikova
  • Birgit Fehrenbacher
  • Peter Dreischer
  • Martin Schaller
  • Ulrich Mrowietz
  • Antonio Martínez-Ruiz
  • Thomas Wieder
  • Vladimir Divoky
  • Ranieri Rossi
  • Florian Lang
  • Martin Köberle
  • Apoptosis.2020 Jul;10.1007/s10495-020-01620-6. doi: 10.1007/s10495-020-01620-6.Epub 2020-07-07.

フランス領ギアナ、アマゾン熱帯雨林の遠隔地における Q 熱発生におけるカピバラとブラシカッターの関与、2014 年

Capybara and Brush Cutter Involvement in Q Fever Outbreak in Remote Area of Amazon Rain Forest, French Guiana, 2014.
  • Jacques-Robert Christen
  • Sophie Edouard
  • Thierry Lamour
  • Enguerrane Martinez
  • Claire Rousseau
  • Franck de Laval
  • François Catzeflis
  • Félix Djossou
  • Didier Raoult
  • Vincent Pommier de Santi
  • Loïc Epelboin
  • Emerging Infect. Dis..2020 May;26(5):993-997. doi: 10.3201/eid2605.190242.

成人急性前骨髄球性白血病患者における全トランスレチノイン酸および三酸化ヒ素とイダルビシンのフロントライン治療による治療成績の改善

Improved Outcomes of All-trans-retinoic Acid and Arsenic Trioxide Plus Idarubicin as a Frontline Treatment in Adult Patients With Acute Promyelocytic Leukemia.
  • Shiwei Yang
  • Rongjun Ma
  • Xiaoli Yuan
  • Li Jiang
  • Jie Shi
  • Jing Yang
  • Pingchong Lei
  • Yuzhu Zang
  • Xiangli Chen
  • Yin Zhang
  • Zhongwen Liu
  • Jianmin Guo
  • Lin Zhang
  • Xiaojian Zhu
  • Zunmin Zhu
  • Clin Lymphoma Myeloma Leuk.2020 Jul;20(7):e382-e391. S2152-2650(19)32015-4. doi: 10.1016/j.clml.2019.10.003.Epub 2019-10-14.

2型糖尿病の経口糖尿病コントロール不良患者における週1回のデュラグルチドとインスリン・グラーギンのグルコース変動に及ぼす影響．

The Effects of Once-Weekly Dulaglutide and Insulin Glargine on Glucose Fluctuation in Poorly Oral-Antidiabetic Controlled Patients with Type 2 Diabetes Mellitus.
  • Jie Wang
  • Hui-Qin Li
  • Xiao-Hua Xu
  • Xiao-Cen Kong
  • Rui Sun
  • Ting Jing
  • Lei Ye
  • Xiao-Fei Su
  • Jian-Hua Ma
  • Biomed Res Int.2019;2019:2682657. doi: 10.1155/2019/2682657.Epub 2019-12-24.

L.の5つの成分は、プロテインキナーゼC-α/ニコチンアミド-アデニンジヌクレオチドリン酸オキシダーゼ経路を阻害するパルミチン酸誘発性肝細胞障害を減衰させる

Five Constituents in L. Attenuate Palmitic Acid-Induced Hepatocyte Injury Inhibiting the Protein Kinase C-α/Nicotinamide-Adenine Dinucleotide Phosphate Oxidase Pathway.
  • Lishan Zhou
  • Jianqiao Tang
  • Xuan Yang
  • Hui Dong
  • Xiaoli Xiong
  • Juan Huang
  • Linli Zhang
  • Huan Qin
  • Suqi Yan
  • Front Pharmacol.2019;10:1589. doi: 10.3389/fphar.2019.01589.Epub 2020-01-28.

全身FFDG PET/MRIと非標的メタボロミクスを統合することで、2型糖尿病における組織特異的なインスリン抵抗性に関する新たな知見が得られる可能性があります

Integration of whole-body [F]FDG PET/MRI with non-targeted metabolomics can provide new insights on tissue-specific insulin resistance in type 2 diabetes.
  • Klev Diamanti
  • Robin Visvanathar
  • Maria J Pereira
  • Marco Cavalli
  • Gang Pan
  • Chanchal Kumar
  • Stanko Skrtic
  • Ulf Risérus
  • Jan W Eriksson
  • Joel Kullberg
  • Jan Komorowski
  • Claes Wadelius
  • Håkan Ahlström
  • Sci Rep.2020 May;10(1):8343. 10.1038/s41598-020-64524-0. doi: 10.1038/s41598-020-64524-0.Epub 2020-05-20.

肝細胞癌の経皮的画像誘導電気化学療法：技術的進歩

Percutaneous image guided electrochemotherapy of hepatocellular carcinoma: technological advancement.
  • Mihajlo Djokic
  • Rok Dezman
  • Maja Cemazar
  • Miha Stabuc
  • Miha Petric
  • Lojze M Smid
  • Rado Jansa
  • Bostjan Plesnik
  • Masa Bosnjak
  • Ursa Lampreht Tratar
  • Blaz Trotovsek
  • Bor Kos
  • Damijan Miklavcic
  • Gregor Sersa
  • Peter Popovic
  • Radiol Oncol.2020 Jun;/j/raon.ahead-of-print/raon-2020-0038/raon-2020-0038.xml. doi: 10.2478/raon-2020-0038.Epub 2020-06-20.

エペ・ラグーン（ナイジェリア、ラゴス）における魚類宿主寄生ベンソー・ペラージック食物連鎖におけるポリ塩化ビフェニル（PCBs）の生物濃縮

Bioaccumulation of Polychlorinated Biphenyls (PCBs) in Fish Host-Parasite Bentho-Pelagic Food Chain in Epe Lagoon, Lagos, Nigeria.
  • Akinsanya Bamidele
  • Minasu Pentho Kuton
  • Akhiromen Dorathy Iniobong
  • Nwadike David Uchenna
  • Joseph Kayode Saliu
  • Ukwa Uche David
  • Bull Environ Contam Toxicol.2020 Jun;10.1007/s00128-020-02893-y. doi: 10.1007/s00128-020-02893-y.Epub 2020-06-05.

LOPH：ネコ白血病ウイルス常在地域で開発されたネコ高悪性度多中心リンパ腫または縦隔リンパ腫に対する新規化学療法プロトコール

LOPH: a novel chemotherapeutic protocol for feline high-grade multicentric or mediastinal lymphoma, developed in an area endemic for feline leukemia virus.
  • Rodrigo S Horta
  • Larissa M Souza
  • Bruna V Sena
  • Isabella O Almeida
  • Tâmara A Jaretta
  • Marcela M Pimenta
  • Archivaldo Reche Júnior
  • J. Feline Med. Surg..2020 Jul;:1098612X20926893. doi: 10.1177/1098612X20926893.Epub 2020-07-20.

共同研究。LC-MS/MSと組み合わせた効率的な単一酵素抽出を用いた食品中の総葉酸の定量

Collaborative study: Quantification of total folate in food using an efficient single-enzyme extraction combined with LC-MS/MS.
  • Petra Ložnjak Švarc
  • Eystein Oveland
  • Hanna Sara Strandler
  • Susanna Kariluoto
  • Esther Campos-Giménez
  • Elise Ivarsen
  • Isabelle Malaviole
  • Carla Motta
  • Michael Rychlik
  • Lisa Striegel
  • Jette Jakobsen
  • Food Chem.2020 Jul;333:127447. S0308-8146(20)31309-1. doi: 10.1016/j.foodchem.2020.127447.Epub 2020-07-04.

地域密着型慢性疾患運動リハビリテーションプログラム「MedEx Wellness」への参加が身体的、臨床的、心理的健康に及ぼす影響。コホート試験のための研究計画書

The effect of participating in MedEx Wellness, a community-based chronic disease exercise rehabilitation programme, on physical, clinical and psychological health: A study protocol for a cohort trial.
  • Bróna Kehoe
  • Fiona Skelly
  • Niall Moyna
  • Mairéad Cantwell
  • Lorraine Boran
  • Leslie Daly
  • Andrew McCarren
  • Kieran Dowd
  • Catherine Woods
  • Noel McCaffrey
  • Lisa Loughney
  • Contemp Clin Trials Commun.2020 Sep;19:100591. S2451-8654(20)30075-2. doi: 10.1016/j.conctc.2020.100591.Epub 2020-06-18.

クラゲのゲノムには、ホメオボックス遺伝子群とスモールRNA処理の保存性が明らかになっている

Jellyfish genomes reveal distinct homeobox gene clusters and conservation of small RNA processing.
  • Wenyan Nong
  • Jianquan Cao
  • Yiqian Li
  • Zhe Qu
  • Jin Sun
  • Thomas Swale
  • Ho Yin Yip
  • Pei Yuan Qian
  • Jian-Wen Qiu
  • Hoi Shan Kwan
  • William Bendena
  • Stephen Tobe
  • Ting Fung Chan
  • Kevin Y Yip
  • Ka Hou Chu
  • Sai Ming Ngai
  • Karl Yk Tsim
  • Peter W H Holland
  • Jerome H L Hui
  • Nat Commun.2020 Jun;11(1):3051. 10.1038/s41467-020-16801-9. doi: 10.1038/s41467-020-16801-9.Epub 2020-06-19.

マルチモダリティ心血管イメージング時の右室機能の予後を探る上で最も有用なイメージングパラメータは何か？

What is the most useful imaging parameter to explore the prognostic value of the right ventricular function at the time of multimodality cardiovascular imaging?
  • Stéphanie Cazalbou
  • Vanessa Chong Fah Shen
  • Antoine Petermann
  • Damien Eyharts
  • Pauline Fournier
  • Eve Cariou
  • Yoan Lavie-Badie
  • Alexia Hennig
  • Jérôme Roncalli
  • Hervé Rousseau
  • Didier Carrié
  • Michel Galinier
  • Isabelle Berry
  • Olivier Lairez
  • Echocardiography.2020 Jul;doi: 10.1111/echo.14686.Epub 2020-07-20.

バイオメカニクス的評価と歯科インプラントの正確な配置の組み合わせ：上顎と下顎の機能的再構成における仮想手術の新しい概念

Combination of biomechanical evaluation and accurate placement of dental implants: a new concept of virtual surgery in maxillary and mandibular functional reconstruction.
  • H-Q Zhang
  • Q-X Li
  • Y-Y Wang
  • Z-S Wang
  • Z-Y Lin
  • L-J Sha
  • D-M Zhang
  • J Liu
  • J-J Wang
  • J-S Li
  • S Fan
  • Br J Oral Maxillofac Surg.2020 01;58(1):62-68. S0266-4356(19)30706-5. doi: 10.1016/j.bjoms.2019.10.310.Epub 2019-11-11.

早期および中期ステージの肝細胞癌の治療におけるヨード125シードと併用した肝動脈化学塞栓療法とラジオ波焼灼療法を併用した肝動脈化学塞栓療法

Transarterial chemoembolization combined with iodine 125 seeds versus transarterial chemoembolization combined with radiofrequency ablation in the treatment of early- and intermediate-stage hepatocellular carcinoma.
  • Lei Chen
  • Xuefeng Kan
  • Tao Sun
  • Yanqiao Ren
  • Yanyan Cao
  • Liangliang Yan
  • Bin Liang
  • Bin Xiong
  • Chuansheng Zheng
  • BMC Gastroenterol.2020 Jun;20(1):205. 10.1186/s12876-020-01355-3. doi: 10.1186/s12876-020-01355-3.Epub 2020-06-29.

CWPおよびPDR遺伝子の不活性化による原生植物酵母を用いた高感度ダイオキシン検出のためのレポーター遺伝子アッセイの改良

Improvement of reporter gene assay for highly sensitive dioxin detection using protoplastic yeast with inactivation of CWP and PDR genes.
  • Masanobu Kawanishi
  • Kentaro Mori
  • Rina Yamada
  • Sayoko Ito-Harashima
  • Takashi Yagi
  • Environ Sci Pollut Res Int.2020 Mar;27(9):9227-9235. 10.1007/s11356-019-07484-x. doi: 10.1007/s11356-019-07484-x.Epub 2020-01-08.

チリの母乳を介したアンデスウイルスの母子感染

Mother-to-Child Transmission of Andes Virus through Breast Milk, Chile.
  • Marcela Ferrés
  • Constanza Martínez-Valdebenito
  • Jenniffer Angulo
  • Carolina Henríquez
  • Jorge Vera-Otárola
  • María José Vergara
  • Javier Pérez
  • Jorge Fernández
  • Viviana Sotomayor
  • María Francisca Valdés
  • Diego González-Candia
  • Nicole D Tischler
  • Cecilia Vial
  • Pablo Vial
  • Gregory Mertz
  • Nicole Le Corre
  • Emerging Infect. Dis..2020 Aug;26(8):1885-1888. doi: 10.3201/eid2608.200204.

ベラプロストは、低酸素誘発性肺高血圧症のラットから得られた肺動脈平滑筋細胞におけるEP4受容体を介してKVチャネルの発現と機能をアップレギュレートする

Beraprost Upregulates KV Channel Expression and Function via EP4 Receptor in Pulmonary Artery Smooth Muscle Cells Obtained from Rats with Hypoxia-Induced Pulmonary Hypertension.
  • Hua Tian
  • Fenling Fan
  • Jie Geng
  • Jizhao Deng
  • Hongyan Tian
  • J. Vasc. Res..2019;56(4):204-214. 000500424. doi: 10.1159/000500424.Epub 2019-06-12.

救急救命技師が治療した院外心停止患者の転帰は、基本的な救急救命技師と比較して改善された。JCS-ReSS研究報告書

Improved outcomes for out-of-hospital cardiac arrest patients treated by emergency life-saving technicians compared with basic emergency medical technicians: A JCS-ReSS study report.
  • Hiromichi Naito
  • Tetsuya Yumoto
  • Takashi Yorifuji
  • Yoshio Tahara
  • Naohiro Yonemoto
  • Hiroshi Nonogi
  • Ken Nagao
  • Takanori Ikeda
  • Naoki Sato
  • Hiroyuki Tsutsui
  • Resuscitation.2020 May;S0300-9572(20)30186-6. doi: 10.1016/j.resuscitation.2020.05.007.Epub 2020-05-15.

プライマリ・ケア施設の高密度化は虚血性心疾患死亡率とは逆相関しているが、脳卒中死亡率とは相関していない。日本の二次医療圏レベルの生態学的カウントデータ

Higher Density of Primary Care Facilities Is Inversely Associated with Ischemic Heart Disease Mortality, but Not with Stroke Mortality: A Japanese Secondary Medical Service Area Level Ecological Count Data.
  • Yasuaki Saijo
  • Eiji Yoshioka
  • Yukihiro Sato
  • Tohoku J. Exp. Med..2020 07;251(3):217-224. doi: 10.1620/tjem.251.217.

膀胱癌に対する開腹手術およびロボット支援型根治的膀胱摘出術を受けた患者では、肥満は短期的な周術期転帰と関連していた

Obesity is associated with adverse short-term perioperative outcomes in patients treated with open and robot-assisted radical cystectomy for bladder cancer.
  • Marina Deuker
  • L Franziska Stolzenbach
  • Claudia Collà Ruvolo
  • Luigi Nocera
  • Mila Mansour
  • Zhe Tian
  • Frederik C Roos
  • Andreas Becker
  • Luis A Kluth
  • Derya Tilki
  • Shahrokh F Shariat
  • Fred Saad
  • Felix K H Chun
  • Pierre I Karakiewicz
  • Urol. Oncol..2020 Jul;S1078-1439(20)30291-X. doi: 10.1016/j.urolonc.2020.06.020.Epub 2020-07-16.

血小板（機能不全）機能と輸血閾値を評価するための心肺バイパス後の多重電極アグリゴメトリー。コンコーダンス研究

Multiple Electrode Aggregometry After Cardiopulmonary Bypass to Assess Platelet (Dys)-Function and Transfusion Threshold: A Concordance Study.
  • Elisabetta Auci
  • Luigi Vetrugno
  • Ilaria Riccardi
  • Alessandro Brussa
  • Daniele Orso
  • Antonio Baroselli
  • Andrea Gigante
  • Roberta Cecotti
  • Flavio Bassi
  • Ugolino Livi
  • Tiziana Bove
  • J. Cardiothorac. Vasc. Anesth..2020 Jun;S1053-0770(20)30602-9. doi: 10.1053/j.jvca.2020.06.060.Epub 2020-06-24.

シリアハムスターのDMBA誘発口腔扁平上皮癌において、シリンジ酸は分子マーカーが関与する細胞増殖、生存、アポトーシス、炎症、血管新生を調節することを明らかにした

Syringic acid modulates molecular marker-involved cell proliferation, survival, apoptosis, inflammation, and angiogenesis in DMBA-induced oral squamous cell carcinoma in Syrian hamsters.
  • Velu Periyannan
  • Vijayalakshmi Annamalai
  • Vinothkumar Veerasamy
  • J. Biochem. Mol. Toxicol..2020 Jul;:e22574. doi: 10.1002/jbt.22574.Epub 2020-07-08.

コアグラーゼ陰性および-陽性ブドウ球菌感染に対するシグナル伝達リンパ球活性化分子ファミリー7（SLAMF7）遺伝子の構造および機能解析

Structural and functional analysis of the signaling lymphocytic activation molecule family 7 (SLAMF7) gene in response to infection with coagulase-negative and -positive staphylococci.
  • A Korwin-Kossakowska
  • K Ropka-Molik
  • T Ząbek
  • T Szmatoła
  • P Brzozowska
  • B Gralak
  • E Kawecka-Grochocka
  • E Bagnicka
  • J. Dairy Sci..2020 Jul;S0022-0302(20)30516-6. doi: 10.3168/jds.2019-17398.Epub 2020-07-16.

冷たい大気圧プラズマ：バイオメディカル用途向けに設計されたポリ(2-オキサゾリン)ベースのコーティング剤の調製のためのシンプルで効率的な戦略

Cold atmospheric pressure plasma: simple and efficient strategy for preparation of poly(2-oxazoline)-based coatings designed for biomedical applications.
  • Petra Šrámková
  • Anna Zahoranová
  • Jakub Kelar
  • Zlata Kelar Tučeková
  • Monika Stupavská
  • Richard Krumpolec
  • Jana Jurmanová
  • Dušan Kováčik
  • Mirko Černák
  • Sci Rep.2020 Jun;10(1):9478. 10.1038/s41598-020-66423-w. doi: 10.1038/s41598-020-66423-w.Epub 2020-06-11.

湿式微細藻類からのバイオディーゼル製造のための細胞破壊と脂質抽出を促進するために、切替可能な溶媒N,N,N',N'-テトラエチル-1,3-プロパンジアミンをカチオン性界面活性剤に解離させた

Switchable solvent N, N, N', N'-tetraethyl-1, 3-propanediamine was dissociated into cationic surfactant to promote cell disruption and lipid extraction from wet microalgae for biodiesel production.
  • Jun Cheng
  • Hao Guo
  • Yi Qiu
  • Ze Zhang
  • Yuxiang Mao
  • Lei Qian
  • Weijuan Yang
  • Ji-Yeon Park
  • Bioresour. Technol..2020 Sep;312:123607. S0960-8524(20)30879-8. doi: 10.1016/j.biortech.2020.123607.Epub 2020-05-30.

消化器内科医と患者が、新型コロナウイルス2019（COVID-19）パンデミック時のテレヘルスサービスへの高い満足度を報告

Gastroenterologists and Patients Report High Satisfaction Rates with Telehealth Services during the Novel Coronavirus 2019 (COVID-19) Pandemic.
  • Avi Dobrusin
  • Fadi Hawa
  • Mark Gladshteyn
  • Paul Corsello
  • Kevin Harlen
  • Charlie Walsh
  • Latha Alaparthi
  • Michael Weinstein
  • Nadeem Baig
  • Andrew Sousa
  • Naresh T Gunaratnam
  • Clin. Gastroenterol. Hepatol..2020 Jul;S1542-3565(20)30976-9. doi: 10.1016/j.cgh.2020.07.014.Epub 2020-07-11.

敗血症性ショック患者における血管プレッサー要件に対するデクスメデトミジンの効果：Sedation Practice in Intensive Care Evaluation SPICEIII試験のサブグループ分析

The effect of dexmedetomidine on vasopressor requirements in patients with septic shock: a subgroup analysis of the Sedation Practice in Intensive Care Evaluation [SPICE III] Trial.
  • Luca Cioccari
  • Nora Luethi
  • Michael Bailey
  • Yahya Shehabi
  • Belinda Howe
  • Anna S Messmer
  • Helena K Proimos
  • Leah Peck
  • Helen Young
  • Glenn M Eastwood
  • Tobias M Merz
  • Jukka Takala
  • Stephan M Jakob
  • Rinaldo Bellomo
  • Crit Care.2020 07;24(1):441. 10.1186/s13054-020-03115-x. doi: 10.1186/s13054-020-03115-x.Epub 2020-07-16.

太りすぎ/肥満のヒスパニック/ラテン系の子供と大人のための文化的対応型ケアのモデルに、植物ベースの食品選択の増加を組み込む

Incorporating an Increase in Plant-Based Food Choices into a Model of Culturally Responsive Care for Hispanic/Latino Children and Adults Who Are Overweight/Obese.
  • Pramil N Singh
  • Jessica Steinbach
  • Anna Nelson
  • Wendy Shih
  • Mary D'Avila
  • Selene Castilla
  • Michael Jordan
  • William J McCarthy
  • David Hayes-Bautista
  • Hector Flores
  • Int J Environ Res Public Health.2020 Jul;17(13). E4849. doi: 10.3390/ijerph17134849.Epub 2020-07-06.

メチシリン耐性黄色ブドウ球菌に対する膜透過性、アポトーシス、バイオフィルム形成とプロテオミクス解析の組み合わせによる精油の抗菌機構を探る

Exploring the antibacterial mechanism of essential oils by membrane permeability, apoptosis and biofilm formation combination with proteomics analysis against methicillin-resistant staphylococcus aureus.
  • Cailin Tang
  • Jiali Chen
  • Lixia Zhang
  • Rongfei Zhang
  • Sichen Zhang
  • Shaoxia Ye
  • Zhimin Zhao
  • Depo Yang
  • Int. J. Med. Microbiol..2020 Jul;310(5):151435. S1438-4221(20)30045-X. doi: 10.1016/j.ijmm.2020.151435.Epub 2020-06-03.

成人および小児における腸チフス感染症の病原体ゲノム調査では、臨床転帰と感染遺伝子型との間に関連性はないことが明らかになっている

Pathogen genomic surveillance of typhoidal infection in adults and children reveals no association between clinical outcomes and infecting genotypes.
  • Carl D Britto
  • Sitarah Mathias
  • Ashish Bosco
  • Zoe A Dyson
  • Gordon Dougan
  • Savitha Raveendran
  • V L Abin
  • Sanju Jose
  • Savitha Nagaraj
  • Kathryn E Holt
  • Andrew J Pollard
  • Trop Med Health.2020;48:58. 247. doi: 10.1186/s41182-020-00247-2.Epub 2020-07-13.

エクソームシークエンシングによる慢性腸管偽閉塞乳児のムコ多糖症I型の偶発的診断

Incidental diagnosis of mucopolysaccharidosis type I in an infant with chronic intestinal pseudoobstruction by exome sequencing.
  • Auriane Cospain
  • Christèle Dubourg
  • Swellen Gastineau
  • Samia Pichard
  • Virginie Gandemer
  • Jacinthe Bonneau
  • Marie de Tayrac
  • Caroline Moreau
  • Sylvie Odent
  • Laurent Pasquier
  • Lena Damaj
  • Alinoë Lavillaureix
  • Mol Genet Metab Rep.2020 Sep;24:100621. S2214-4269(20)30067-7. doi: 10.1016/j.ymgmr.2020.100621.Epub 2020-07-07.

肝移植後のミニ開腹手術下での経腸的アプローチを用いたハイブリッドインターベンショナルラジオロジーによる左心室性シャントの切除術。症例報告

Obliteration of a Portosystemic Shunt by Hybrid Interventional Radiology Using a Transmesenteric Approach Under Minilaparotomy After Liver Transplantation: A Case Report.
  • Sotaro Fukuhara
  • Masahiro Ohira
  • Keigo Chosa
  • Yasutaka BaBa
  • Michinori Hamaoka
  • Naoki Tanimine
  • Hiroshi Morimoto
  • Shintaro Kuroda
  • Hiroyuki Tahara
  • Kentaro Ide
  • Tsuyoshi Kobayashi
  • Kazuo Awai
  • Hideki Ohdan
  • Transplant. Proc..2020 Jul;S0041-1345(20)30348-1. doi: 10.1016/j.transproceed.2020.06.014.Epub 2020-07-15.

化学的ストレスを受けたタバコBY-2懸濁液培養細胞における抗酸化特性を有する揮発性有機硫黄化合物の細胞死に伴う放出

Cell death associated release of volatile organic sulphur compounds with antioxidant properties in chemical-challenged tobacco BY-2 suspension cultured cells.
  • Elena T Iakimova
  • Zhenia P Yordanova
  • Simona M Cristescu
  • Frans F M Harren
  • Ernst J Woltering
  • J. Plant Physiol..2020 Aug;251:153223. S0176-1617(20)30113-9. doi: 10.1016/j.jplph.2020.153223.Epub 2020-07-02.

成人発症スティル病におけるIL-1受容体拮抗薬による治療後のグルココルチコイド併用量の減少。観察研究のシステマティックレビューとメタアナリシス

The reduction of concomitant glucocorticoids dosage following treatment with IL-1 receptor antagonist in adult onset Still's disease. A systematic review and meta-analysis of observational studies.
  • Piero Ruscitti
  • Francesco Ursini
  • Jurgen Sota
  • Roberto De Giorgio
  • Luca Cantarini
  • Roberto Giacomelli
  • Ther Adv Musculoskelet Dis.2020;12:1759720X20933133. 10.1177_1759720X20933133. doi: 10.1177/1759720X20933133.Epub 2020-06-17.

KCNJ10遺伝子の新規変異は、特徴的な運動失調、感音性難聴、痙縮の臨床表現型に関連している

Novel mutations in the KCNJ10 gene associated to a distinctive ataxia, sensorineural hearing loss and spasticity clinical phenotype.
  • Matias Morin
  • Anna-Lena Forst
  • Paula Pérez-Torre
  • Adriano Jiménez-Escrig
  • Verónica Barca-Tierno
  • Eva García-Galloway
  • Richard Warth
  • Jose Luis Lopez-Sendón Moreno
  • Miguel Angel Moreno-Pelayo
  • Neurogenetics.2020 Apr;21(2):135-143. 10.1007/s10048-020-00605-6. doi: 10.1007/s10048-020-00605-6.Epub 2020-02-15.

大腸癌におけるルテニウム-フロレチン複合体の化学療法の可能性を明らかにする分子機構を解読する

Decrypting the Molecular Mechanistic Pathways Delineating the Chemotherapeutic Potential of Ruthenium-Phloretin Complex in Colon Carcinoma Correlated with the Oxidative Status and Increased Apoptotic Events.
  • Guoguo Jin
  • Zhenjiang Zhao
  • Tania Chakraborty
  • Aikyadeep Mandal
  • Arka Roy
  • Souvik Roy
  • Zhiping Guo
  • Oxid Med Cell Longev.2020;2020:7690845. doi: 10.1155/2020/7690845.Epub 2020-05-31.

本試験は、糖尿病予備軍を対象に、Allium hookeri 抽出物の抗糖尿病効果を評価するための無作為化二重盲検プラセボ対照クロスオーバー臨床試験である

A randomized, double-blind, placebo-controlled crossover clinical trial to evaluate the anti-diabetic effects of Allium hookeri extract in the subjects with prediabetes.
  • Soo-Hyun Park
  • Ui-Jin Bae
  • Eun-Kyung Choi
  • Su-Jin Jung
  • Sung-Hyen Lee
  • Jae-Heon Yang
  • You-Suk Kim
  • Do-Youn Jeong
  • Hyun-Ju Kim
  • Byung-Hyun Park
  • Soo-Wan Chae
  • BMC Complement Med Ther.2020 Jul;20(1):211. 10.1186/s12906-020-03005-3. doi: 10.1186/s12906-020-03005-3.Epub 2020-07-06.

不死化したヒト子宮内膜間質細胞を移植した場合と移植していない場合の比較シークレットームプロファイル解析。予備的解析

Comparative secretome profile analysis of cultured immortalized human endometrial stromal cells supplemented with implanted versus nonimplanted blastocyst-conditioned medium: A preliminary analysis.
  • Feng Xiong
  • ZhiHong Yao
  • PeiLin Chen
  • Qing Sun
  • HuiXian Zhong
  • CaiYun Wan
  • Yong Zeng
  • J. Obstet. Gynaecol. Res..2020 Jul;doi: 10.1111/jog.14359.Epub 2020-07-08.

食品廃棄物の嫌気性消化における微量元素の役割プロセスの安定性、揮発性脂肪酸の阻害からの回復、微生物群集の動態

Role of trace elements in anaerobic digestion of food waste: Process stability, recovery from volatile fatty acid inhibition and microbial community dynamics.
  • Wanli Zhang
  • Lintong Li
  • Xue Wang
  • Wanli Xing
  • Rundong Li
  • Tianhua Yang
  • Dan Lv
  • Bioresour. Technol..2020 Jul;315:123796. S0960-8524(20)31068-3. doi: 10.1016/j.biortech.2020.123796.Epub 2020-07-09.

カプサイシン感受性線維は、ラットの外傷性脳損傷後の眼窩周囲のアロディニアと炎症細胞の活性化を媒介している。外傷後頭痛におけるTRPV1チャネルの関与

Capsaicin-sensitive fibers mediate periorbital allodynia and activation of inflammatory cells after traumatic brain injury in rats: Involvement of TRPV1 channels in post-traumatic headache.
  • Fernando da Silva Fiorin
  • Caroline Cunha do Espírito Santo
  • Raphael Santos do Nascimento
  • Gustavo Cassol
  • Evelini Plácido
  • Adair Roberto Soares Santos
  • Jefferson Luiz Brum Marques
  • Patricia S Brocardo
  • Michele Rechia Fighera
  • Luiz Fernando Freire Royes
  • Neuropharmacology.2020 Jun;:108215. S0028-3908(20)30283-5. doi: 10.1016/j.neuropharm.2020.108215.Epub 2020-06-20.

長時間作用型低分子化合物を用いたHIVカプシドタンパク質の臨床的標的化

Clinical targeting of HIV capsid protein with a long-acting small molecule.
  • John O Link
  • Martin S Rhee
  • Winston C Tse
  • Jim Zheng
  • John R Somoza
  • William Rowe
  • Rebecca Begley
  • Anna Chiu
  • Andrew Mulato
  • Derek Hansen
  • Eric Singer
  • Luong K Tsai
  • Rujuta A Bam
  • Chien-Hung Chou
  • Eda Canales
  • Gediminas Brizgys
  • Jennifer R Zhang
  • Jiayao Li
  • Michael Graupe
  • Philip Morganelli
  • Qi Liu
  • Qiaoyin Wu
  • Randall L Halcomb
  • Roland D Saito
  • Scott D Schroeder
  • Scott E Lazerwith
  • Steven Bondy
  • Debi Jin
  • Magdeleine Hung
  • Nikolai Novikov
  • Xiaohong Liu
  • Armando G Villaseñor
  • Carina E Cannizzaro
  • Eric Y Hu
  • Robert L Anderson
  • Todd C Appleby
  • Bing Lu
  • Judy Mwangi
  • Albert Liclican
  • Anita Niedziela-Majka
  • Giuseppe A Papalia
  • Melanie H Wong
  • Stephanie A Leavitt
  • Yili Xu
  • David Koditek
  • George J Stepan
  • Helen Yu
  • Nikos Pagratis
  • Sheila Clancy
  • Shekeba Ahmadyar
  • Terrence Z Cai
  • Scott Sellers
  • Scott A Wolckenhauer
  • John Ling
  • Christian Callebaut
  • Nicolas Margot
  • Renee R Ram
  • Ya-Pei Liu
  • Rob Hyland
  • Gary I Sinclair
  • Peter J Ruane
  • Gordon E Crofoot
  • Cheryl K McDonald
  • Diana M Brainard
  • Latesh Lad
  • Swami Swaminathan
  • Wesley I Sundquist
  • Roman Sakowicz
  • Anne E Chester
  • William E Lee
  • Eric S Daar
  • Stephen R Yant
  • Tomas Cihlar
  • Nature.2020 Jul;10.1038/s41586-020-2443-1. doi: 10.1038/s41586-020-2443-1.Epub 2020-07-01.

急性冠症候群患者における年齢および体重に応じたプラスグレルの投与量とチカグレロールの標準投与量の比較。無作為化試験の結果

Age- and Weight-Adapted Dose of Prasugrel Versus Standard Dose of Ticagrelor in Patients With Acute Coronary Syndromes: Results From a Randomized Trial.
  • Maurizio Menichelli
  • Franz-Josef Neumann
  • Gjin Ndrepepa
  • Katharina Mayer
  • Jochen Wöhrle
  • Isabell Bernlochner
  • Gert Richardt
  • Bernhard Witzenbichler
  • Dirk Sibbing
  • Senta Gewalt
  • Dominick J Angiolillo
  • Shqipdona Lahu
  • Christian W Hamm
  • Alexander Hapfelmeier
  • Dietmar Trenk
  • Karl-Ludwig Laugwitz
  • Heribert Schunkert
  • Stefanie Schüpke
  • Adnan Kastrati
  • Ann. Intern. Med..2020 Jul;doi: 10.7326/M20-1806.Epub 2020-07-21.

ヌクレオチドアナログは、炎症やオートファジーに依存しないβ-カテニンを介して大腸炎関連がんを予防する

A Nucleotide Analog Prevents Colitis-Associated Cancer via Beta-Catenin Independently of Inflammation and Autophagy.
  • Yong Hua Sheng
  • Rabina Giri
  • Julie Davies
  • Veronika Schreiber
  • Saleh Alabbas
  • Ramya Movva
  • Yaowu He
  • Andy Wu
  • John Hooper
  • Brett McWhinney
  • Iulia Oancea
  • Gregor Kijanka
  • Sumaira Hasnain
  • Andrew J Lucke
  • David P Fairlie
  • Michael A McGuckin
  • Timothy H Florin
  • Jakob Begun
  • Cell Mol Gastroenterol Hepatol.2020 Jun;S2352-345X(20)30088-6. doi: 10.1016/j.jcmgh.2020.05.012.Epub 2020-06-01.

AKT2, STK38L, HMGA2, ETS1, E2F5を直接標的としたmiR-493-3pによる卵巣癌細胞のアポトーシス誘導

Induction of apoptosis in ovarian cancer cells by miR-493-3p directly targeting AKT2, STK38L, HMGA2, ETS1 and E2F5.
  • Michael Kleemann
  • Helga Schneider
  • Kristian Unger
  • Jeremias Bereuther
  • Simon Fischer
  • Philip Sander
  • E Marion Schneider
  • Pamela Fischer-Posovszky
  • Christian U Riedel
  • René Handrick
  • Kerstin Otte
  • Cell. Mol. Life Sci..2019 Feb;76(3):539-559. 10.1007/s00018-018-2958-x. doi: 10.1007/s00018-018-2958-x.Epub 2018-11-03.

神経受容体イメージングのための灰白質と血漿中の定常状態CFlumazenilレベルの調整のためのボーラス注入スキーム

Bolus Infusion Scheme for the Adjustment of Steady State [C]Flumazenil Levels in the Grey Matter and in the Blood Plasma for Neuroreceptor Imaging.
  • Jörg Mauler
  • Alexander Heinzel
  • Andreas Matusch
  • Hans Herzog
  • Irene Neuner
  • Jürgen Scheins
  • Christine Wyss
  • Jürgen Dammers
  • Markus Lang
  • Johannes Ermert
  • Bernd Neumaier
  • Karl-Josef Langen
  • N Jon Shah
  • Neuroimage.2020 Jul;:117160. S1053-8119(20)30646-7. doi: 10.1016/j.neuroimage.2020.117160.Epub 2020-07-14.

経静脈的鉛抽出からの主要な合併症と死亡率に対するセンターボリュームとプロシージャの位置の効果：ESC EHRA EORP European Lead Extraction ConTRolled ELECTRa レジストリのサブアナリシス

The effect of centre volume and procedure location on major complications and mortality from transvenous lead extraction: an ESC EHRA EORP European Lead Extraction ConTRolled ELECTRa registry subanalysis.
  • Baldeep S Sidhu
  • Justin Gould
  • Catey Bunce
  • Mark Elliott
  • Vishal Mehta
  • Charles Kennergren
  • Christian Butter
  • Jean-Claude Deharo
  • Andrzej Kutarski
  • Aldo P Maggioni
  • Angelo Auricchio
  • Karl-Heinz Kuck
  • Carina Blomström-Lundqvist
  • Maria Grazia Bongiorni
  • Christopher A Rinaldi
  • Europace.2020 Jul;euaa131. doi: 10.1093/europace/euaa131.Epub 2020-07-20.

定量的肺CTと臨床データを用いた新規コロナウイルス疾患（COVID-19）の評価：短期予後の予測

Evaluation of novel coronavirus disease (COVID-19) using quantitative lung CT and clinical data: prediction of short-term outcome.
  • João Matos
  • Francesco Paparo
  • Ilaria Mussetto
  • Lorenzo Bacigalupo
  • Alessio Veneziano
  • Silvia Perugin Bernardi
  • Ennio Biscaldi
  • Enrico Melani
  • Giancarlo Antonucci
  • Paolo Cremonesi
  • Marco Lattuada
  • Alberto Pilotto
  • Emanuele Pontali
  • Gian Andrea Rollandi
  • Eur Radiol Exp.2020 06;4(1):39. 10.1186/s41747-020-00167-0. doi: 10.1186/s41747-020-00167-0.Epub 2020-06-26.

CLL 患者における COVID-19 のアウトカム：国際的な多施設共同試験の経験

Outcomes of COVID-19 in Patients with CLL: A Multicenter, International Experience.
  • Anthony R Mato
  • Lindsey Elizabeth Roeker
  • Nicole Lamanna
  • John Allan
  • Lori Ann Leslie
  • John M Pagel
  • Krish Patel
  • Anders Osterborg
  • Daniel Wojenski
  • Manali Kamdar
  • Scott F Huntington
  • Matthew S Davids
  • Jennifer R Brown
  • Darko Antic
  • Ryan W Jacobs
  • Inhye E Ahn
  • Jeffrey J Pu
  • Krista Isaac
  • Paul M Barr
  • Chaitra Ujjani
  • Mark Blaine Geyer
  • Ellin Berman
  • Andrew D Zelenetz
  • Nikita Malakhov
  • Richard R Furman
  • Michael Koropsak
  • Neil Bailey
  • Lotta Hansson
  • Guilherme Fleury Perini
  • Shuo Ma
  • Christine E Ryan
  • Adrian Wiestner
  • Craig A Portell
  • Mazyar Shadman
  • Elise A Chong
  • Danielle M Brander
  • Suchitra Sundaram
  • Amanda N Seddon
  • Erlene Seymour
  • Meera Patel
  • Nicolas Martinez-Calle
  • Talha Munir
  • Renata Walewska
  • Angus Broom
  • Harriet Sarah Walter
  • Dima El-Sharkawi
  • Helen Parry
  • Matthew R Wilson
  • Piers E Patten
  • José-Ángel Hernández-Rivas
  • Fatima Miras
  • Noemi Fernández Escalada
  • Paola Ghione
  • Chadi Nabhan
  • Sonia Lebowitz
  • Erica B Bhavsar
  • Javier López-Jiménez
  • Daniel Naya
  • Jose Antonio Garcia-Marco
  • Sigrid S Skånland
  • Raul Cordoba
  • Toby Andrew Eyre
  • Blood.2020 Jul;blood.2020006965. doi: 10.1182/blood.2020006965.Epub 2020-07-20.

2種の熱帯植物（Tetrapleura tetrapteraとQuassia undulata）の水性抽出物は、スコポラミン誘発性健忘症ラットにおいて空間的・非空間的作業記憶を改善した。神経細胞のコリン作動系と抗酸化系の影響

Aqueous extracts of two tropical ethnobotanicals (Tetrapleura tetraptera and Quassia undulata) improved spatial and non-spatial working memories in scopolamine-induced amnesic rats: Influence of neuronal cholinergic and antioxidant systems.
  • Veronica O Odubanjo
  • Emmanuel O Ibukun
  • Ganiyu Oboh
  • Stephen A Adefegha
  • Biomed. Pharmacother..2018 Mar;99:198-204. S0753-3322(17)35005-9. doi: 10.1016/j.biopha.2018.01.043.

心房細動患者における薬剤溶出ステント vs ベアメタルステントの安全性と有効性。システマティックレビューとメタアナリシス

Safety and efficacy of drug eluting stents vs bare metal stents in patients with atrial fibrillation: A systematic review and meta-analysis.
  • Antonia Sambola
  • Pau Rello
  • Toni Soriano
  • Deepak L Bhatt
  • Vinay Pasupuleti
  • Christopher P Cannon
  • C Michael Gibson
  • Willem J M Dewilde
  • Gregory Y H Lip
  • Eric D Peterson
  • K E Juhani Airaksinen
  • Tuomas Kiviniemi
  • Laurent Fauchier
  • Lorenz Räber
  • Juan M Ruiz-Nodar
  • Maciej Banach
  • Héctor Bueno
  • Adrian V Hernandez
  • Thromb. Res..2020 Jul;195:128-135. S0049-3848(20)30301-7. doi: 10.1016/j.thromres.2020.07.010.Epub 2020-07-09.

米国成人の間でのアルコール関与の段階での幼少期の不利な経験（ACE）と移行。進行と回帰

Adverse childhood experiences (ACEs) and transitions in stages of alcohol involvement among US adults: Progression and regression.
  • Anika A H Alvanzo
  • Carla L Storr
  • Beth Reboussin
  • Kerry M Green
  • Ramin Mojtabai
  • Lareina N La Flair
  • Bernadette A Cullen
  • Ryoko Susukida
  • Marissa Seamans
  • Rosa M Crum
  • Child Abuse Negl.2020 Jul;107:104624. S0145-2134(20)30279-9. doi: 10.1016/j.chiabu.2020.104624.Epub 2020-07-16.

バングラデシュにおける養殖および野生由来の淡水エビ（Macrobrachium rosenbergii）における微量金属の生物濃縮とヒトの健康リスク評価

Bioaccumulation of trace metals in freshwater prawn, Macrobrachium rosenbergii from farmed and wild sources and human health risk assessment in Bangladesh.
  • Farhana Mostafiz
  • Md Monirul Islam
  • Badhan Saha
  • Md Kamal Hossain
  • Mohammad Moniruzzaman
  • Md Habibullah-Al-Mamun
  • Environ Sci Pollut Res Int.2020 May;27(14):16426-16438. 10.1007/s11356-020-08028-4. doi: 10.1007/s11356-020-08028-4.Epub 2020-03-02.

メラノーマのMCL1バイアスを標的にすると、BRAFとERK1/2経路阻害剤のアポトーシスの可能性が解き放たれる

Targeting melanoma's MCL1 bias unleashes the apoptotic potential of BRAF and ERK1/2 pathway inhibitors.
  • Matthew J Sale
  • Emma Minihane
  • Noel R Monks
  • Rebecca Gilley
  • Frances M Richards
  • Kevin P Schifferli
  • Courtney L Andersen
  • Emma J Davies
  • Mario Aladren Vicente
  • Eiko Ozono
  • Aleksandra Markovets
  • Jonathan R Dry
  • Lisa Drew
  • Vikki Flemington
  • Theresa Proia
  • Duncan I Jodrell
  • Paul D Smith
  • Simon J Cook
  • Nat Commun.2019 11;10(1):5167. 10.1038/s41467-019-12409-w. doi: 10.1038/s41467-019-12409-w.Epub 2019-11-14.

遅発性ハザードに対する稲作農家の適応策に影響を与える要因：フィリピンとベトナムにおける塩水浸水の事例

Factors Influencing Measure-based Adaptation of Rice Farmers for Slow-Onset Hazard: the Case of Saltwater Inundation in the Philippines and Vietnam.
  • Catherine Roween C Almaden
  • Thanh Tung Diep
  • Agnes C Rola
  • Rowena D T Baconguis
  • Juan M Pulhin
  • Jose V Camacho
  • Rico C Ancog
  • Environ Manage.2020 Jul;10.1007/s00267-020-01332-2. doi: 10.1007/s00267-020-01332-2.Epub 2020-07-17.

足底筋膜症患者に対する橈骨体外衝撃波治療（rESWT）、sham-rESWT、標準化された運動プログラム、または通常のケアの有効性：二重盲検、無作為化、シャムコントロール試験の試験プロトコール

The effectiveness of radial extracorporeal shock wave therapy (rESWT), sham-rESWT, standardised exercise programme or usual care for patients with plantar fasciopathy: study protocol for a double-blind, randomised, sham-controlled trial.
  • Marte Heide
  • Marianne Mørk
  • Cecilie Røe
  • Jens Ivar Brox
  • Aasne Fenne Hoksrud
  • Trials.2020 Jun;21(1):589. 10.1186/s13063-020-04510-z. doi: 10.1186/s13063-020-04510-z.Epub 2020-06-29.

ブラジル北東部、アラリペ盆地のロムアルド層（アルビアン）の基底部に生息する最初の獣脚類恐竜（コエロサウルス属、セロポダ）

The first theropod dinosaur (Coelurosauria, Theropoda) from the base of the Romualdo Formation (Albian), Araripe Basin, Northeast Brazil.
  • Juliana Manso Sayão
  • Antônio Álamo Feitosa Saraiva
  • Arthur Souza Brum
  • Renan Alfredo Machado Bantim
  • Rafael Cesar Lima Pedroso de Andrade
  • Xin Cheng
  • Flaviana Jorge de Lima
  • Helder de Paula Silva
  • Alexander W A Kellner
  • Sci Rep.2020 Jul;10(1):10892. 10.1038/s41598-020-67822-9. doi: 10.1038/s41598-020-67822-9.Epub 2020-07-10.

レースのペーシングの早期シフトは、睡眠不足下でのシングル・エクササイズ・ウルトラマラソンにおける将来のパフォーマンスを予測することができる

Earlier shift in race pacing can predict future performance during a single-effort ultramarathon under sleep deprivation.
  • Allison J Brager
  • Sukru Demiral
  • John Choynowski
  • Jess Kim
  • Bill Campbell
  • Vincent F Capaldi
  • Guido Simonelli
  • Steve Hammer
  • Sleep Sci.2020 Jan-Mar;13(1):25-31. doi: 10.5935/1984-0063.20190132.

同種造血幹細胞移植を受けている成人ハイリスク急性リンパ芽球性白血病患者に対する TMLI と非 TMLI の条件付けレジメンの転帰の比較：単一施設での経験

Comparing the outcomes between TMLI and non-TMLI conditioning regimens for adult high-risk acute lymphoblastic leukemia patients undergoing allogeneic hematopoietic stem cell transplantation: a single-center experience.
  • Xiaoyan Zhao
  • Xuan Lu
  • Liang Tang
  • Han Yan
  • Wenlan Chen
  • Wei Shi
  • Zhaodong Zhong
  • Yong You
  • Linghui Xia
  • Yu Hu
  • Huafang Wang
  • Leuk. Lymphoma.2020 Jul;:1-9. doi: 10.1080/10428194.2020.1789621.Epub 2020-07-10.

難治性ランゲルハンス細胞組織球症の小児における造血幹細胞移植の全国的なレトロスペクティブレビュー

Nationwide retrospective review of hematopoietic stem cell transplantation in children with refractory Langerhans cell histiocytosis.
  • Kazuko Kudo
  • Miho Maeda
  • Nobuhiro Suzuki
  • Hirokazu Kanegane
  • Shouichi Ohga
  • Eiichi Ishii
  • Yoko Shioda
  • Toshihiko Imamura
  • Shinsaku Imashuku
  • Yukiko Tsunematsu
  • Mikiya Endo
  • Akira Shimada
  • Yuuki Koga
  • Yoshiko Hashii
  • Maiko Noguchi
  • Masami Inoue
  • Ken Tabuchi
  • Akira Morimoto
  • Int. J. Hematol..2020 Jan;111(1):137-148. 10.1007/s12185-019-02760-5. doi: 10.1007/s12185-019-02760-5.Epub 2019-11-22.

ファバ豆由来ポリフェノール（ガテン酸、カテキン）の3T3-L1細胞株における血糖降下作用、酸化ストレス電位およびキサンチンオキシダーゼ活性の検討：分子ドッキングおよびシミュレーション研究への洞察

Investigation of hypoglycemic effects, oxidative stress potential and xanthine-oxidase activity of polyphenols (gallic acid, catechin) derived from faba bean on 3T3-L1 cell line: insights into molecular docking and simulation study.
  • Dhiraj Kumar Choudhary
  • Navaneet Chaturvedi
  • Amit Singh
  • Abha Mishra
  • Toxicol Res (Camb).2020 Jun;9(3):308-322. tfaa025. doi: 10.1093/toxres/tfaa025.Epub 2020-05-21.

エバリに関連した入院と死亡

Hospitalizations and Deaths Associated with EVALI.
  • Angela K Werner
  • Emilia H Koumans
  • Kevin Chatham-Stephens
  • Phillip P Salvatore
  • Christina Armatas
  • Paul Byers
  • Charles R Clark
  • Isaac Ghinai
  • Stacy M Holzbauer
  • Kristen A Navarette
  • Melissa L Danielson
  • Sascha Ellington
  • Erin D Moritz
  • Emily E Petersen
  • Emily A Kiernan
  • Grant T Baldwin
  • Peter Briss
  • Christopher M Jones
  • Brian A King
  • Vikram Krishnasamy
  • Dale A Rose
  • Sarah Reagan-Steiner
  • N. Engl. J. Med..2020 04;382(17):1589-1598. doi: 10.1056/NEJMoa1915314.

マイクロプレート常磁性ビーズとフィロペプチドミクスに基づいたダブルバレルクロマトグラフィー-タンデム質量分析法による細菌単離株のハイスループットなプロテオタイピング

High-throughput proteotyping of bacterial isolates by double barrel chromatography-tandem mass spectrometry based on microplate paramagnetic beads and phylopeptidomics.
  • Karim Hayoun
  • Jean-Charles Gaillard
  • Olivier Pible
  • Béatrice Alpha-Bazin
  • Jean Armengaud
  • J Proteomics.2020 Jun;226:103887. S1874-3919(20)30255-4. doi: 10.1016/j.jprot.2020.103887.Epub 2020-06-30.

選択されたイオントロピー性受容体と電圧依存性イオンチャネル。ヒト誘導多能性幹細胞(iPSC)由来侵害受容体の機能性を向上させる

Selected Ionotropic Receptors and Voltage-Gated Ion Channels: More Functional Competence for Human Induced Pluripotent Stem Cell (iPSC)-Derived Nociceptors.
  • Clemens L Schoepf
  • Maximilian Zeidler
  • Lisa Spiecker
  • Georg Kern
  • Judith Lechner
  • Kai K Kummer
  • Michaela Kress
  • Brain Sci.2020 Jun;10(6). E344. doi: 10.3390/brainsci10060344.Epub 2020-06-03.

残存大腸ポリープや線維性大腸ポリープの内視鏡治療のための機器・手技（動画あり）

Devices and techniques for endoscopic treatment of residual and fibrotic colorectal polyps (with videos).
  • Arvind J Trindade
  • Nikhil A Kumta
  • Manoop S Bhutani
  • Vinay Chandrasekhara
  • Pichamol Jirapinyo
  • Kumar Krishnan
  • Joshua Melson
  • Rahul Pannala
  • Mansour A Parsi
  • Allison R Schulman
  • Guru Trikudanathan
  • Rabindra R Watson
  • John T Maple
  • David R Lichtenstein
  • Gastrointest. Endosc..2020 Jul;S0016-5107(20)30244-3. doi: 10.1016/j.gie.2020.03.018.Epub 2020-07-05.

Canadian Longitudinal Study on Agingのベースラインデータを用いて、45～64歳の女性におけるうつ病、ホルモン療法、および更年期移行について検討した

Depression, hormone therapy, and the menopausal transition among women aged 45 to 64 years using Canadian Longitudinal Study on aging baseline data.
  • Alison K Shea
  • Nazmul Sohel
  • Anne Gilsing
  • Alexandra J Mayhew
  • Lauren E Griffith
  • Parminder Raina
  • Menopause.2020 Jul;27(7):763-770. doi: 10.1097/GME.0000000000001540.

神経集中治療におけるマイクロダイアリシスと近接拡張アッセイ技術を用いたヒト外傷性脳損傷における炎症のタンパク質バイオマーカーのモニタリング

Monitoring of Protein Biomarkers of Inflammation in Human Traumatic Brain Injury Using Microdialysis and Proximity Extension Assay Technology in Neurointensive Care.
  • Philip Dyhrfort
  • Qiujin Shen
  • Fredrik Clausen
  • Måns Thulin
  • Per Enblad
  • Masood Kamali-Moghaddam
  • Anders Lewén
  • Lars Hillered
  • J. Neurotrauma.2019 10;36(20):2872-2885. doi: 10.1089/neu.2018.6320.Epub 2019-06-17.

ダニ細胞株の実験室株と新規ノミ由来のフィールド株の単離と伝播

Isolation and Propagation of Laboratory Strains and a Novel Flea-Derived Field Strain of in Tick Cell Lines.
  • Jing Jing Khoo
  • Timothy J Kurtti
  • Nurul Aini Husin
  • Alexandra Beliavskaia
  • Fang Shiang Lim
  • Mulya Mustika Sari Zulkifli
  • Alaa M Al-Khafaji
  • Catherine Hartley
  • Alistair C Darby
  • Grant L Hughes
  • Sazaly AbuBakar
  • Benjamin L Makepeace
  • Lesley Bell-Sakyi
  • Microorganisms.2020 Jul;8(7). E988. doi: 10.3390/microorganisms8070988.Epub 2020-07-01.

EPR分光法によるヒト40Sリボソームサブユニットと短鎖RNAの相互作用の解明

Exploring the interactions of short RNAs with the human 40S ribosomal subunit near the mRNA entry site by EPR spectroscopy.
  • Alexey A Malygin
  • Olesya A Krumkacheva
  • Dmitri M Graifer
  • Ivan O Timofeev
  • Anastasia S Ochkasova
  • Maria I Meschaninova
  • Alya G Venyaminova
  • Matvey V Fedin
  • Michael Bowman
  • Galina G Karpova
  • Elena G Bagryanskaya
  • Nucleic Acids Res..2019 12;47(22):11850-11860. 5625535. doi: 10.1093/nar/gkz1039.

70歳未満の患者における修復不能な後臼蓋腱板断裂の治療のための逆全肩関節形成術と比較して、上層カプセル再建後の最短2年間の臨床成績

Minimum 2-year clinical outcomes after superior capsule reconstruction compared with reverse total shoulder arthroplasty for the treatment of irreparable posterosuperior rotator cuff tears in patients younger than 70 years.
  • Lucca Lacheta
  • Marilee P Horan
  • Brandon T Goldenberg
  • Grant J Dornan
  • Brendan Higgins
  • Peter J Millett
  • J Shoulder Elbow Surg.2020 Jun;S1058-2746(20)30303-7. doi: 10.1016/j.jse.2020.04.002.Epub 2020-06-09.

腎機能障害を有するサルコイドーシス患者における1,25ジヒドロキシビタミンDの増加

Increase of 1,25 dihydroxyvitamin D in sarcoidosis patients with renal dysfunction.
  • Naoya Toriu
  • Keiichi Sumida
  • Masahiko Oguro
  • Yoichi Oshima
  • Hiroki Mizuno
  • Eiko Hasegawa
  • Tatsuya Suwabe
  • Masahiro Kawada
  • Toshiharu Ueno
  • Noriko Hayami
  • Akinari Sekine
  • Rikako Hiramatsu
  • Masayuki Yamanouchi
  • Junichi Hoshino
  • Naoki Sawa
  • Kenmei Takaichi
  • Kenichi Ohashi
  • Keiichi Kinowaki
  • Takeshi Fujii
  • Ryosuke Date
  • Yoshifumi Ubara
  • Clin. Exp. Nephrol..2019 Oct;23(10):1202-1210. 10.1007/s10157-019-01760-3. doi: 10.1007/s10157-019-01760-3.Epub 2019-06-25.

最近発症した1型糖尿病患者における全原性脂肪組織由来の間質/幹細胞とビタミンDの補給。3ヶ月間の追跡調査パイロット試験

Allogenic Adipose Tissue-Derived Stromal/Stem Cells and Vitamin D Supplementation in Patients With Recent-Onset Type 1 Diabetes Mellitus: A 3-Month Follow-Up Pilot Study.
  • Debora B Araujo
  • Joana R Dantas
  • Karina R Silva
  • Débora L Souto
  • Maria de Fátima C Pereira
  • Jessica P Moreira
  • Ronir R Luiz
  • Cesar S Claudio-Da-Silva
  • Monica A L Gabbay
  • Sergio A Dib
  • Carlos E B Couri
  • Angelo Maiolino
  • Carmen L K Rebelatto
  • Debora R Daga
  • Alexandra C Senegaglia
  • Paulo R S Brofman
  • Leandra Santos Baptista
  • José E P Oliveira
  • Lenita Zajdenverg
  • Melanie Rodacki
  • Front Immunol.2020;11:993. doi: 10.3389/fimmu.2020.00993.Epub 2020-06-02.

マウス胚性幹細胞のRNAディープシーケンシング解析により同定された化学物質の有害性スクリーニングのためのマイクロRNAバイオマーカー

MicroRNA biomarkers for chemical hazard screening identified by RNA deep sequencing analysis in mouse embryonic stem cells.
  • Hiroshi Aoki
  • Hidenori Tani
  • Kaoru Nakamura
  • Hiroaki Sato
  • Masaki Torimura
  • Tetsuya Nakazato
  • Toxicol. Appl. Pharmacol..2020 Apr;392:114929. S0041-008X(20)30053-3. doi: 10.1016/j.taap.2020.114929.Epub 2020-02-24.

カルシウム酸。24,25-ジヒドロキシビタミンDで処理したマウスの血清中の25-ヒドロキシビタミンDの末端C24-酸化生成物および関連する中間体のin vivoでの検出および定量

Calcioic acid: In vivo detection and quantification of the terminal C24-oxidation product of 25-hydroxyvitamin D and related intermediates in serum of mice treated with 24,25-dihydroxyvitamin D.
  • Martin Kaufmann
  • Corine Martineau
  • Alice Arabian
  • Mary Traynor
  • René St-Arnaud
  • Glenville Jones
  • J. Steroid Biochem. Mol. Biol..2019 04;188:23-28. S0960-0760(18)30521-1. doi: 10.1016/j.jsbmb.2018.12.001.Epub 2018-12-13.

miR-122ノックアウトマウスにおけるRelBのアップレギュレーションは、肝臓およびマクロファージにおける炎症性ケモカイン/サイトカインレベルの上昇に寄与する

Upregulation of RelB in the miR-122 knockout mice contributes to increased levels of proinflammatory chemokines/cytokines in the liver and macrophages.
  • Ke-Hsun Hsu
  • Chin-Wen Wei
  • Yi-Ru Su
  • Tung Chou
  • Yueh-Ling Lin
  • Fu-Chen Yang
  • Ann-Ping Tsou
  • Chia-Lin Hsu
  • Ping-Hui Tseng
  • Nien-Jung Chen
  • Kuo-Shyang Jeng
  • Chuen-Miin Leu
  • Immunol. Lett..2020 Jul;226:22-30. S0165-2478(20)30346-1. doi: 10.1016/j.imlet.2020.06.015.Epub 2020-07-02.

ヒトPA200とPA200-20Sの複合体の低温電子顕微鏡構造から、プロテアソームのゲート開口とPA200の2つの開口が制御されていることが明らかになった

Cryo-EM structures of the human PA200 and PA200-20S complex reveal regulation of proteasome gate opening and two PA200 apertures.
  • Hongxin Guan
  • Youwang Wang
  • Ting Yu
  • Yini Huang
  • Mianhuan Li
  • Abdullah F U H Saeed
  • Vanja Perčulija
  • Daliang Li
  • Jia Xiao
  • Dongmei Wang
  • Ping Zhu
  • Songying Ouyang
  • PLoS Biol..2020 03;18(3):e3000654. PBIOLOGY-D-19-02639. doi: 10.1371/journal.pbio.3000654.Epub 2020-03-05.

重み付け遺伝子共発現ネットワークと競合内因性RNAネットワーク解析による変形性変形性メニスカスにおけるlncRNAとmRNAのバイオマーカーの同定

Identification of lncRNA and mRNA Biomarkers in Osteoarthritic Degenerative Meniscus by Weighted Gene Coexpression Network and Competing Endogenous RNA Network Analysis.
  • Jun Zhao
  • Yu Su
  • Jianfei Jiao
  • Zhengchun Wang
  • Xiangchun Fang
  • Xuefeng He
  • Xiaofeng Zhang
  • Zhao Liu
  • Xilin Xu
  • Biomed Res Int.2020;2020:2123787. doi: 10.1155/2020/2123787.Epub 2020-05-20.

PHBV/PLA/Col膜のデュラプラスティは、脊髄損傷ラットにおいて、NLRP3複合体とM1マクロファージの分極を抑制することで軸索再生を促進した

Duraplasty of PHBV/PLA/Col membranes promotes axonal regeneration by inhibiting NLRP3 complex and M1 macrophage polarization in rats with spinal cord injury.
  • Tengfei Zhao
  • Kan Xu
  • Qionghua Wu
  • Chenggui Wang
  • Shining Xiao
  • Heyangzi Li
  • Teng He
  • Linlin Wang
  • Fangcai Li
  • Qixin Chen
  • FASEB J..2020 Jul;doi: 10.1096/fj.202000190RR.Epub 2020-07-20.

中等期肝細胞がんの治療戦略を変えるパラダイム：アジア太平洋地域原発性肝がん専門家コンセンサス・ステートメント

A Changing Paradigm for the Treatment of Intermediate-Stage Hepatocellular Carcinoma: Asia-Pacific Primary Liver Cancer Expert Consensus Statements.
  • Masatoshi Kudo
  • Kwang-Hyub Han
  • Sheng-Long Ye
  • Jian Zhou
  • Yi-Hsiang Huang
  • Shi-Ming Lin
  • Chung-Kwe Wang
  • Masafumi Ikeda
  • Stephen Lam Chan
  • Su Pin Choo
  • Shiro Miyayama
  • Ann Lii Cheng
  • Liver Cancer.2020 Jun;9(3):245-260. lic-0009-0245. doi: 10.1159/000507370.Epub 2020-05-13.

炎症は、薬を服用していない双極性障害では、島嶼部の機能的接続性の低下と関連している

Inflammation is associated with decreased functional connectivity of insula in unmedicated bipolar disorder.
  • Pan Chen
  • Feng Chen
  • Guanmao Chen
  • Shuming Zhong
  • JiaYing Gong
  • Hui Zhong
  • Tao Ye
  • Guixian Tang
  • Jurong Wang
  • Zhenye Luo
  • Zhangzhang Qi
  • Yanbin Jia
  • Hengwen Yang
  • Zhinan Yin
  • Li Huang
  • Ying Wang
  • Brain Behav. Immun..2020 Jul;S0889-1591(20)30243-9. doi: 10.1016/j.bbi.2020.07.004.Epub 2020-07-17.

前臨床での抗血栓活性を有する高親和性の経口バイオアベイラブル大環状FXIa阻害剤の発見

Discovery of a High Affinity, Orally Bioavailable Macrocyclic FXIa Inhibitor with Antithrombotic Activity in Preclinical Species.
  • Wu Yang
  • Yufeng Wang
  • Amy Lai
  • Charles G Clark
  • James R Corte
  • Tianan Fang
  • Paul J Gilligan
  • Yoon Jeon
  • Kumar B Pabbisetty
  • Richard A Rampulla
  • Arvind Mathur
  • Mahammed Kaspady
  • Premsai Rai Neithnadka
  • Arunachalam Arumugam
  • Sivashankaran Raju
  • Karen A Rossi
  • Joseph E Myers
  • Steven Sheriff
  • Zhen Lou
  • Joanna J Zheng
  • Silvi A Chacko
  • Jeffrey M Bozarth
  • Yiming Wu
  • Earl J Crain
  • Pancras C Wong
  • Dietmar A Seiffert
  • Joseph M Luettgen
  • Patrick Y S Lam
  • Ruth R Wexler
  • William R Ewing
  • J. Med. Chem..2020 Jul;63(13):7226-7242. doi: 10.1021/acs.jmedchem.0c00464.Epub 2020-06-17.

ダール塩感受性高血圧、腎障害、Tリンパ球トランスクリプトームに対する食事の影響

Dietary Effects on Dahl Salt-Sensitive Hypertension, Renal Damage, and the T Lymphocyte Transcriptome.
  • Justine M Abais-Battad
  • Ammar J Alsheikh
  • Xiaoqing Pan
  • Daniel J Fehrenbach
  • John Henry Dasinger
  • Hayley Lund
  • Michelle L Roberts
  • Alison J Kriegel
  • Allen W Cowley
  • Srividya Kidambi
  • Theodore A Kotchen
  • Pengyuan Liu
  • Mingyu Liang
  • David L Mattson
  • Hypertension.2019 10;74(4):854-863. doi: 10.1161/HYPERTENSIONAHA.119.12927.Epub 2019-09-03.

タイで栽培された27種の植物化学物質、抗酸化物質、体外での抗アルツハイマー性の比較

Comparison of Phytochemicals, Antioxidant, and In Vitro Anti-Alzheimer Properties of Twenty-Seven spp. Cultivated in Thailand.
  • Piya Temviriyanukul
  • Varittha Sritalahareuthai
  • Kriskamol Na Jom
  • Butsara Jongruaysup
  • Somying Tabtimsri
  • Kanchana Pruesapan
  • Sirinapa Thangsiri
  • Woorawee Inthachat
  • Dalad Siriwan
  • Somsri Charoenkiatkul
  • Uthaiwan Suttisansanee
  • Molecules.2020 Jun;25(11). E2600. doi: 10.3390/molecules25112600.Epub 2020-06-03.

インプラント表面のアモルファスカーボン修飾：FAK/ERK1/2シグナル伝達経路を介して多様なバイオマテリアルの骨形成分化を促進するための一般的な戦略

Amorphous carbon modification on implant surface: a general strategy to enhance osteogenic differentiation for diverse biomaterials via FAK/ERK1/2 signaling pathways.
  • Xinran Zhang
  • Haotian Li
  • Jiaqiang Liu
  • Hui Wang
  • Wenjun Sun
  • Kaili Lin
  • Xudong Wang
  • Steve Guofang Shen
  • J Mater Chem B.2019 04;7(15):2518-2533. doi: 10.1039/c8tb02850h.Epub 2019-03-19.

非毒性の青色光（453nm）がヒト皮膚線維芽細胞の細胞抗酸化能、TGF-β1シグナル伝達、および筋線維芽細胞の筋線維形成に与える影響

The impact of non-toxic blue light (453 nm) on cellular antioxidative capacity, TGF-β1 signaling, and myofibrogenesis of human skin fibroblasts.
  • Julia M Krassovka
  • Christoph V Suschek
  • Max Prost
  • Vera Grotheer
  • Jennifer L Schiefer
  • Erhan Demir
  • Paul C Fuchs
  • Joachim Windolf
  • Ewa K Stürmer
  • Christian Opländer
  • J. Photochem. Photobiol. B, Biol..2020 Jul;209:111952. S1011-1344(20)30402-4. doi: 10.1016/j.jphotobiol.2020.111952.Epub 2020-07-06.

大脳皮質発生の奇形における標的的再配列：遺伝子型とフェノタイプの相関関係

Targeted re-sequencing in malformations of cortical development: genotype-phenotype correlations.
  • Andrea Accogli
  • Mariasavina Severino
  • Antonella Riva
  • Francesca Madia
  • Ganna Balagura
  • Michele Iacomino
  • Barbara Carlini
  • Simona Baldassari
  • Thea Giacomini
  • Carolina Croci
  • Livia Pisciotta
  • Tullio Messana
  • Antonella Boni
  • Angelo Russo
  • Leonilda Bilo
  • Rosa Tonziello
  • Antonietta Coppola
  • Alessandro Filla
  • Oriano Mecarelli
  • Rosario Casalone
  • Francesco Pisani
  • Raffaele Falsaperla
  • Silvia Marino
  • Pasquale Parisi
  • Alessandro Ferretti
  • Maurizio Elia
  • Anna Luchetti
  • Donatella Milani
  • Francesca Vanadia
  • Laura Silvestri
  • Erika Rebessi
  • Eliana Parente
  • Giampaolo Vatti
  • Maria Margherita Mancardi
  • Lino Nobili
  • Valeria Capra
  • Vincenzo Salpietro
  • Pasquale Striano
  • Federico Zara
  • Seizure.2020 Jun;80:145-152. S1059-1311(20)30153-9. doi: 10.1016/j.seizure.2020.05.023.Epub 2020-06-03.

ワルデンストロームマクログロブリン血症患者を対象としたイブルチニブ単剤療法の奏効率と生存率 臨床試験のオンとオフの結果について

Response and Survival Outcomes to Ibrutinib Monotherapy for Patients With Waldenström Macroglobulinemia on and off Clinical Trials.
  • Jorge J Castillo
  • Joshua N Gustine
  • Kirsten Meid
  • Catherine A Flynn
  • Maria G Demos
  • Maria L Guerrera
  • Cristina Jimenez
  • Amanda Kofides
  • Xia Liu
  • Manit Munshi
  • Nicholas Tsakmaklis
  • Christopher J Patterson
  • Lian Xu
  • Guang Yang
  • Zachary R Hunter
  • Steven P Treon
  • Hemasphere.2020 Jun;4(3):e363. HemaSphere-2019-0201. doi: 10.1097/HS9.0000000000000363.Epub 2020-05-21.

アフリカトリパノソーマの成長を阻害し、発生制御遺伝子の転写レベルに影響を与える臨床的に承認された低分子の同定

Identification of clinically approved small molecules that inhibit growth and affect transcript levels of developmentally regulated genes in the African trypanosome.
  • Madison Elle Walsh
  • Eleanor Mary Naudzius
  • Savanah Jessica Diaz
  • Theodore William Wismar
  • Mikhail Martchenko Shilman
  • Danae Schulz
  • PLoS Negl Trop Dis.2020 03;14(3):e0007790. PNTD-D-19-01546. doi: 10.1371/journal.pntd.0007790.Epub 2020-03-13.

二硫化モリブデンをポリエーテルエーテルケトンに組み込むことで、機械的性能、トライボロジー性能、細胞適合性を向上させた人工関節用のバイオコンポジットが得られた

Incorporation of molybdenum disulfide into polyetheretherketone creating biocomposites with improved mechanical, tribological performances and cytocompatibility for artificial joints applications.
  • Xinke Lv
  • Xuehong Wang
  • Songchao Tang
  • Dongliang Wang
  • Lili Yang
  • Axiang He
  • Tingting Tang
  • Jie Wei
  • Colloids Surf B Biointerfaces.2020 May;189:110819. S0927-7765(20)30049-7. doi: 10.1016/j.colsurfb.2020.110819.Epub 2020-01-21.

下肢バイパスのための強化された回復プログラムの実施

Implementation of an Enhanced Recovery Program for Lower Extremity Bypass.
  • Adam Witcher
  • John Axley
  • Zdenek Novak
  • Maria Laygo-Prickett
  • Meredith Guthrie
  • Anisa Xhaja
  • Daniel I Chu
  • S Danielle Brokus
  • Emily L Spangler
  • Marc A Passman
  • Katharine L McGinigle
  • Benjamin J Pearce
  • Ryne Schlitz
  • Roland T Short
  • Jeffrey W Simmons
  • Richard C Cross
  • Graeme E McFarland
  • Adam W Beck
  • J. Vasc. Surg..2020 Jul;S0741-5214(20)31581-0. doi: 10.1016/j.jvs.2020.06.106.Epub 2020-07-15.

エレクトロスピンPCLベースのナノファイバー <i>Arrabidaea chica</i> Verlot - <i>Pterodon pubescens</i> Benth loaded:線維芽細胞形成の相乗効果

Electrospun PCL-based nanofibers <i>Arrabidaea chica</i> Verlot - <i>Pterodon pubescens</i> Benth loaded: synergic effect in fibroblast formation.
  • Taís Helena Costa Salles
  • Fabiana Volpe-Zanutto
  • Ilza Maria de Oliveira Sousa
  • Daisy Machado
  • Ana Caroline Zanatta
  • Wagner Vilegas
  • Marcelo Lancellotti
  • Mary Ann Foglio
  • Marcos Akira d'Ávila
  • Biomed Mater.2020 Jun;doi: 10.1088/1748-605X/ab9bb1.Epub 2020-06-11.

血漿脂質バイオマーカー解析により、血管性痴呆における脂質の変化が明らかになった

Plasma lipidomic biomarker analysis reveals distinct lipid changes in vascular dementia.
  • Yue Liu
  • Daniel K Y Chan
  • Anbupalam Thalamuthu
  • Wei Wen
  • Jiyang Jiang
  • Matthew Paradise
  • Teresa Lee
  • John Crawford
  • Matthew Wai Kin Wong
  • Ying Hua Xu
  • Anne Poljak
  • Russell Pickford
  • Perminder S Sachdev
  • Nady Braidy
  • Comput Struct Biotechnol J.2020;18:1613-1624. S2001-0370(20)30289-0. doi: 10.1016/j.csbj.2020.06.001.Epub 2020-06-09.

保存されていないヒト脂肪lincRNAの探索により、脂肪細胞の代謝を制御する役割が明らかになった

Interrogation of nonconserved human adipose lincRNAs identifies a regulatory role of in adipocyte metabolism.
  • Xuan Zhang
  • Chenyi Xue
  • Jennie Lin
  • Jane F Ferguson
  • Amber Weiner
  • Wen Liu
  • Yumiao Han
  • Christine Hinkle
  • Wenjun Li
  • Hongfeng Jiang
  • Sager Gosai
  • Melanie Hachet
  • Benjamin A Garcia
  • Brian D Gregory
  • Raymond E Soccio
  • John B Hogenesch
  • Patrick Seale
  • Mingyao Li
  • Muredach P Reilly
  • Sci Transl Med.2018 06;10(446). eaar5987. doi: 10.1126/scitranslmed.aar5987.

炎症性腸疾患の若年患者における仙腸炎の徴候検出における磁気共鳴腸管造影検査の有用性

Usefulness of magnetic resonance enterography in detecting signs of sacroiliitis in young patients with inflammatory bowel disease.
  • Teresa Giani
  • Azzurra Bernardini
  • Massimo Basile
  • Marco Di Maurizo
  • Anna Perrone
  • Sara Renzo
  • Viola Filistrucchi
  • Rolando Cimaz
  • Paolo Lionetti
  • Pediatr Rheumatol Online J.2020 Jun;18(1):42. 10.1186/s12969-020-00433-w. doi: 10.1186/s12969-020-00433-w.Epub 2020-06-03.

天然着色料の分析と生物学的活性。オプンティア種の生物多様性を探索するための分子マーカーとの関連付け

Natural colourants analysis and biological activities. Association to molecular markers to explore the biodiversity of Opuntia species.
  • Nidhal Salem
  • Myriam Lamine
  • Bilel Damergi
  • Fatma Ezahra
  • Nedia Feres
  • Selim Jallouli
  • Majdi Hammami
  • Saber Khammassi
  • Sawsen Selmi
  • Salem Elkahoui
  • Ferid Limam
  • Olfa Tabben
  • Phytochem Anal.2020 Jun;doi: 10.1002/pca.2954.Epub 2020-06-16.

アカラシアにおける腹腔鏡下ヘラーミオトミーまたは空気圧拡張術：少なくとも10年以上の追跡調査を行ったプロスペクティブ無作為化試験の結果

Laparoscopic Heller myotomy or pneumatic dilatation in achalasia: results of a prospective, randomized study with at least a decade of follow-up.
  • Ehsan Sediqi
  • Alexandros Tsoposidis
  • Ville Wallenius
  • Hans Axelsson
  • Jan Persson
  • Erik Johnsson
  • Lars Lundell
  • Srdjan Kostic
  • Surg Endosc.2020 Apr;10.1007/s00464-020-07541-4. doi: 10.1007/s00464-020-07541-4.Epub 2020-04-17.

バルト海哺乳類における線虫の寄生、ドイツ海岸からのグレイアザラシ（Halichoerus grypus (Fabricius, 1791)）とハーバーポーリス（Phocoena phocoena (L.)）

Nematode Parasites in Baltic Sea Mammals, Grey Seal (Halichoerus grypus (Fabricius, 1791)) and Harbour Porpoise (Phocoena phocoena (L.)), from the German Coast.
  • Michael Gabel
  • Stefan Theisen
  • Harry Wilhelm Palm
  • Michael Dähne
  • Patrick Unger
  • Acta Parasitol..2020 Jul;10.1007/s11686-020-00246-7. doi: 10.1007/s11686-020-00246-7.Epub 2020-07-08.

ラクトバチルス・サリバリウスG60とイヌリンはプロバイオティクス単独やプラセボよりも口腔内口臭や舌苔の治療に効果的か？無作為化臨床試験

Are Lactobacillus salivarius G60 and inulin more efficacious to treat patients with oral halitosis and tongue coating than the probiotic alone and placebo? A randomized clinical trial.
  • Camila Rafaela Mousquer
  • Alvaro Della Bona
  • Daiane Cristina Milani
  • Sidia Maria Callegari-Jacques
  • Karin Ishikawa
  • Marcia Pinto Alves Mayer
  • Cassiano Kuchenbecker Rösing
  • Fernando Fornari
  • J. Periodontol..2020 Jun;91(6):775-783. doi: 10.1002/JPER.19-0089.Epub 2019-12-19.

4-アミノキノリン類の前臨床種における薬物動態の不一致を理解する。4-アミノキノリン類の前臨床試験における薬物動態の解明：ラットおよびイヌの経口薬物動態に及ぼす低透過性および高P糖タンパク質溶出比の影響について

Understanding Pharmacokinetic Disconnect in Preclinical Species for 4-Aminoquinolines: Consequences of Low Permeability and High P-glycoprotein Efflux Ratio on Rat and Dog Oral Pharmacokinetics.
  • Mukesh K Mahajan
  • Elizabeth J Rivera
  • Helen H Sun
  • Rakesh Nagilla
  • Michael P DeMartino
  • Pamela A Haile
  • Linda N Casillas
  • Robert W Marquis
  • Bartholomew J Votta
  • John Bertin
  • Michael A Reilly
  • J Pharm Sci.2020 Jun;S0022-3549(20)30325-7. doi: 10.1016/j.xphs.2020.06.013.Epub 2020-06-18.

埋め立て浸出液に曝露された淡水二枚貝Diplodon parodiziの酸化ストレスと細胞損傷のバイオマーカー

Biomarkers of oxidative stress and cell damage in freshwater bivalves Diplodon parodizi exposed to landfill leachate.
  • Juliani Giselli Prestes
  • Maria Rosa Dmengeon Pedreiro De Souza
  • Priscila Krebsbach Kandalski
  • Tatiana Herrerias
  • Cintia Machado
  • Elen de Arruda Martins
  • Vanessa Abelaira Dos Anjos
  • Ananda Karla Alves Neundorf
  • Diego Mauro Carneiro Pereira
  • Maurício Osvaldo Moura
  • Lucelia Donatti
  • Environ Sci Pollut Res Int.2020 Aug;27(22):28384-28395. 10.1007/s11356-020-08721-4. doi: 10.1007/s11356-020-08721-4.Epub 2020-05-16.

Gタンパク質共役型受容体40アゴニストGW9508は、INS-1細胞におけるプロテインキナーゼCαおよびεの活性化を介して、グルコース刺激型インスリン分泌を増強する

G-protein-coupled receptor 40 agonist GW9508 potentiates glucose-stimulated insulin secretion through activation of protein kinase Cα and ε in INS-1 cells.
  • Takuya Hashimoto
  • Hideo Mogami
  • Daisuke Tsuriya
  • Hiroshi Morita
  • Shigekazu Sasaki
  • Tatsuro Kumada
  • Yuko Suzuki
  • Tetsumei Urano
  • Yutaka Oki
  • Takafumi Suda
  • PLoS ONE.2019;14(9):e0222179. PONE-D-18-08918. doi: 10.1371/journal.pone.0222179.Epub 2019-09-09.

大腸がん手術を受けた患者における栄養不良ユニバーサルスクリーニングツール（MUST）、CT（コンピュータ断層撮影）由来の体組成、全身の炎症、臨床転帰との関連性

The relation between Malnutrition Universal Screening Tool (MUST), computed tomography-derived body composition, systemic inflammation, and clinical outcomes in patients undergoing surgery for colorectal cancer.
  • Arwa S Almasaudi
  • Stephen T McSorley
  • Ross D Dolan
  • Christine A Edwards
  • Donald C McMillan
  • Am. J. Clin. Nutr..2019 12;110(6):1327-1334. 5570571. doi: 10.1093/ajcn/nqz230.

ステロイド受容体コアクチベータ-3（SRC-3）のセリン857位のリン酸化は、p38-MK2軸によって制御されており、NF-κBを介した転写に影響を与えています

Phosphorylation of steroid receptor coactivator-3 (SRC-3) at serine 857 is regulated by the p38-MK2 axis and affects NF-κB-mediated transcription.
  • Anup Shrestha
  • Henrike Bruckmueller
  • Hanne Kildalsen
  • Gurjit Kaur
  • Matthias Gaestel
  • Hilde Ljones Wetting
  • Ingvild Mikkola
  • Ole-Morten Seternes
  • Sci Rep.2020 Jul;10(1):11388. 10.1038/s41598-020-68219-4. doi: 10.1038/s41598-020-68219-4.Epub 2020-07-09.

ナノ構造化が半導体-触媒界面電子移動の架け橋となる。光強度に依存しないエネルギー利用と効率的な太陽光駆動光触媒を実現する

Nanostructuring Bridges Semiconductor-Cocatalyst Interfacial Electron Transfer: Realizing Light-Intensity-Independent Energy Utilization and Efficient Sunlight-Driven Photocatalysis.
  • Zhijian Wang
  • Wei Qiao
  • Mi Yuan
  • Na Li
  • Jiazang Chen
  • J Phys Chem Lett.2020 Jun;11(12):4644-4648. doi: 10.1021/acs.jpclett.0c01043.Epub 2020-06-02.

急性腎不全に対する動脈内注射によるミトコンドリア移植

Mitochondrial Transplantation by Intra-Arterial Injection for Acute Kidney Injury.
  • Ilias P Doulamis
  • Alvise Guariento
  • Thomas Duignan
  • Takashi Kido
  • Arzoo Orfany
  • Mossab Y Saeed
  • Viktoria H Weixler
  • David Blitzer
  • Borami Shin
  • Erin R Snay
  • James A H Inkster
  • Alan B Packard
  • David Zurakowski
  • Thomas Rousselle
  • Amandeep Bajwa
  • Samir M Parikh
  • Isaac E Stillman
  • Pedro J Del Nido
  • James D McCully
  • Am. J. Physiol. Renal Physiol..2020 Jul;doi: 10.1152/ajprenal.00255.2020.Epub 2020-07-20.

精神疾患を持つ人々のプライマリ・ヘルスケアにおける慢性ケアの統合の評価：ネパールにおけるプライマリ・ヘルスケア・ワーカーを対象とした縦断的研究

Evaluating the integration of chronic care elements in primary health care for people with mental illness: a longitudinal study in Nepal conducted among primary health care workers.
  • Nawaraj Upadhaya
  • Mark J D Jordans
  • Ramesh P Adhikari
  • Dristy Gurung
  • Ruwayda Petrus
  • Inge Petersen
  • Ivan H Komproe
  • BMC Health Serv Res.2020 Jul;20(1):632. 10.1186/s12913-020-05491-0. doi: 10.1186/s12913-020-05491-0.Epub 2020-07-09.

癌精巣抗原サイクリンA1は、いくつかのHLA-A*02:01制限T細胞エピトープを有しており、これらは生体内で提示され、認識されます

Cancer testis antigen Cyclin A1 harbors several HLA-A*02:01-restricted T cell epitopes, which are presented and recognized in vivo.
  • Anja Tatjana Teck
  • Sabrina Urban
  • Petra Quass
  • Annika Nelde
  • Heiko Schuster
  • Anne Letsch
  • Antonia Busse
  • Juliane Sarah Walz
  • Ulrich Keilholz
  • Sebastian Ochsenreither
  • Cancer Immunol. Immunother..2020 Jul;69(7):1217-1227. 10.1007/s00262-020-02519-6. doi: 10.1007/s00262-020-02519-6.Epub 2020-03-10.

メタボリックシンドロームを超えてクッシング病では内臓脂肪組織と骨髄脂肪組織が骨量と質を損なう

Beyond the metabolic syndrome: Visceral and marrow adipose tissues impair bone quantity and quality in Cushing's disease.
  • Sérgio Luchini Batista
  • Iana Mizumukai de Araújo
  • Adriana Lelis Carvalho
  • Maria Augusta V S D Alencar
  • Andressa K Nahas
  • Jorge Elias
  • Marcello H Nogueira-Barbosa
  • Carlos E G Salmon
  • Paula C L Elias
  • Ayrton C Moreira
  • Margaret Castro
  • Francisco J A de Paula
  • PLoS ONE.2019;14(10):e0223432. PONE-D-19-07537. doi: 10.1371/journal.pone.0223432.Epub 2019-10-15.

2次元導電性金属有機フレームワークナノワイヤへのマルチメタルの導入により、ベンジルアミンのベンゾニトリルへの優れた電極触媒酸化を可能にした

Multimetal Incorporation into 2D Conductive Metal-Organic Framework Nanowires Enabling Excellent Electrocatalytic Oxidation of Benzylamine to Benzonitrile.
  • Ying Wang
  • Ying-Ying Xue
  • Li-Ting Yan
  • Hai-Peng Li
  • Yong-Peng Li
  • En-Hui Yuan
  • Meng Li
  • Shu-Ni Li
  • Quan-Guo Zhai
  • ACS Appl Mater Interfaces.2020 Jun;12(22):24786-24795. doi: 10.1021/acsami.0c05094.Epub 2020-05-18.

学校を基盤とした健康介入の開発に校長を関与させる。RE-AIMフレームワークを用いた混合方法による成果とプロセスの評価

Involving the headteacher in the development of school-based health interventions: A mixed-methods outcome and process evaluation using the RE-AIM framework.
  • Danielle L Christian
  • Charlotte Todd
  • Jaynie Rance
  • Gareth Stratton
  • Kelly A Mackintosh
  • Frances Rapport
  • Sinead Brophy
  • PLoS ONE.2020;15(4):e0230745. PONE-D-19-31826. doi: 10.1371/journal.pone.0230745.Epub 2020-04-02.

SABREを介してラベル化されていないピリジン、ピラジン、またはメトロニダゾールに供給される驚くべきレベルのN偏光により、mMレベルでのシングルスキャンNMR定量が可能になりました

Remarkable Levels of N Polarization Delivered through SABRE into Unlabeled Pyridine, Pyrazine, or Metronidazole Enable Single Scan NMR Quantification at the mM Level.
  • Marianna Fekete
  • Fadi Ahwal
  • Simon B Duckett
  • J Phys Chem B.2020 Jun;124(22):4573-4580. doi: 10.1021/acs.jpcb.0c02583.Epub 2020-05-26.

野生蜂種の生得的嗜好性の理解：青色および緑色光受容体の波長依存的選択的励起に対する応答

Understanding innate preferences of wild bee species: responses to wavelength-dependent selective excitation of blue and green photoreceptor types.
  • Oksana Ostroverkhova
  • Gracie Galindo
  • Claire Lande
  • Julie Kirby
  • Melissa Scherr
  • George Hoffman
  • Sujaya Rao
  • J. Comp. Physiol. A Neuroethol. Sens. Neural. Behav. Physiol..2018 07;204(7):667-675. 10.1007/s00359-018-1269-x. doi: 10.1007/s00359-018-1269-x.Epub 2018-06-05.

ジクロリド-(1,4,8,11-テトラ-アザ-シクロ-テトラ-デカン-κ)クロム(III)ビス-(ホルムアミド-κ)(1,4,8,11-テトラ-アザ-シクロ-テトラ-デカン-κ)クロム(III)ビス-テトラ-クロリド-亜鉛酸塩(II)の結晶構造

Crystal structure of -di-chlorido-(1,4,8,11-tetra-aza-cyclo-tetra-decane-κ)chromium(III) bis-(form-amide-κ)(1,4,8,11-tetra-aza-cyclo-tetra-decane-κ)chromium(III) bis-[tetra-chlorido-zincate(II)].
  • Dohyun Moon
  • Jong-Ha Choi
  • Acta Crystallogr E Crystallogr Commun.2020 May;76(Pt 5):656-659. vm2231. doi: 10.1107/S2056989020004910.Epub 2020-04-09.

2型糖尿病患者におけるエンパグリフロジンと関連した胸部手術中の好血球性ケトアシドーシスの早期発見。症例報告

Early detection of euglycemic ketoacidosis during thoracic surgery associated with empagliflozin in a patient with type 2 diabetes: A case report.
  • Chie Kitahara
  • Shuhei Morita
  • Shohei Kishimoto
  • Shohei Matsuno
  • Shinsuke Uraki
  • Ken Takeshima
  • Yasushi Furukawa
  • Hidefumi Inaba
  • Hiroshi Iwakura
  • Hiroyuki Ariyasu
  • Hiroto Furuta
  • Masahiro Nishi
  • Takashi Akamizu
  • J Diabetes Investig.2020 Jul;doi: 10.1111/jdi.13365.Epub 2020-07-19.

急性冠症候群の病態における季節的変動

Seasonal Variations in the Pathogenesis of Acute Coronary Syndromes.
  • Osamu Kurihara
  • Masamichi Takano
  • Erika Yamamoto
  • Taishi Yonetsu
  • Tsunekazu Kakuta
  • Tsunenari Soeda
  • Bryan P Yan
  • Filippo Crea
  • Takumi Higuma
  • Shigeki Kimura
  • Yoshiyasu Minami
  • Tom Adriaenssens
  • Niklas F Boeder
  • Holger M Nef
  • Chong Jin Kim
  • Vikas Thondapu
  • Hyung Oh Kim
  • Michele Russo
  • Tomoyo Sugiyama
  • Francesco Fracassi
  • Hang Lee
  • Kyoichi Mizuno
  • Ik-Kyung Jang
  • J Am Heart Assoc.2020 Jul;9(13):e015579. doi: 10.1161/JAHA.119.015579.Epub 2020-07-02.

デジタルマンモグラフィ画像スクリーニング試験からのがん症例を対象としたコンピュータ支援検出の単独感度の評価

Assessing the stand-alone sensitivity of computer-aided detection with cancer cases from the Digital Mammographic Imaging Screening Trial.
  • Elodia B Cole
  • Zheng Zhang
  • Helga S Marques
  • Robert M Nishikawa
  • R Edward Hendrick
  • Martin J Yaffe
  • Wittaya Padungchaichote
  • Cherie Kuzmiak
  • Jatuporn Chayakulkheeree
  • Emily F Conant
  • Laurie L Fajardo
  • Janet Baum
  • Constantine Gatsonis
  • Etta Pisano
  • AJR Am J Roentgenol.2012 Sep;199(3):W392-401. 199/3/W392. doi: 10.2214/AJR.11.7255.

重月経出血に対するレボノルゲストレル子宮内装置の血管効果：子宮動脈、橈骨動脈、螺旋動脈の血行動態の変化と関連しているか？

Vascular effect of levonorgestrel intrauterine system on heavy menstrual bleeding: is it associated with hemodynamic changes in uterine, radial, and spiral arteries?
  • Hanifi Şahin
  • Arif Güngören
  • Burak Sezgin
  • Burak Ün
  • Eda Adeviye Şahin
  • Kenan Dolapçioğlu
  • Rahime Nida Bayik
  • J Obstet Gynaecol.2020 Jun;:1-5. doi: 10.1080/01443615.2019.1671816.Epub 2020-06-23.

クワ（Morus alba L.）苗葉のNaClおよびNaHCOストレスに対する活性酸素代謝および抗酸化機構の生理学的およびプロテオミクス的応答（英文

Physiological and proteomic responses of reactive oxygen species metabolism and antioxidant machinery in mulberry (Morus alba L.) seedling leaves to NaCl and NaHCO stress.
  • Zhang Huihui
  • Li Xin
  • Guan Yupeng
  • Li Mabo
  • Wang Yue
  • An Meijun
  • Zhang Yuehui
  • Liu Guanjun
  • Xu Nan
  • Sun Guangyu
  • Ecotoxicol. Environ. Saf..2020 Apr;193:110259. S0147-6513(20)30098-1. doi: 10.1016/j.ecoenv.2020.110259.Epub 2020-02-22.

2018年に中国で発生したジェノタイプIb日本脳炎ウイルスによる日本脳炎のアウトブレイク。実験室と現地での調査

An outbreak of Japanese encephalitis caused by genotype Ib Japanese encephalitis virus in China, 2018: A laboratory and field investigation.
  • Wenjing Liu
  • Shihong Fu
  • Xuemin Ma
  • Xiaojing Chen
  • Dan Wu
  • Liwei Zhou
  • Qikai Yin
  • Fan Li
  • Ying He
  • Wenwen Lei
  • Yixing Li
  • Songtao Xu
  • Huaqing Wang
  • Zhenhai Wang
  • Huanyu Wang
  • Hong Yu
  • Guodong Liang
  • PLoS Negl Trop Dis.2020 05;14(5):e0008312. PNTD-D-19-01986. doi: 10.1371/journal.pntd.0008312.Epub 2020-05-26.

低体重型神経性食欲不振症と非定型神経性食欲不振症におけるグレリンレベルと海馬白質結合の発達段階依存性の関係

Developmental stage-dependent relationships between ghrelin levels and hippocampal white matter connections in low-weight anorexia nervosa and atypical anorexia nervosa.
  • Lauren Breithaupt
  • Natalia Chunga-Iturry
  • Amanda E Lyall
  • Suheyla Cetin-Karayumak
  • Kendra R Becker
  • Jennifer J Thomas
  • Meghan Slattery
  • Nikos Makris
  • Franziska Plessow
  • Ofer Pasternak
  • Laura M Holsen
  • Marek Kubicki
  • Madhusmita Misra
  • Elizabeth A Lawson
  • Kamryn T Eddy
  • Psychoneuroendocrinology.2020 May;119:104722. S0306-4530(20)30141-4. doi: 10.1016/j.psyneuen.2020.104722.Epub 2020-05-23.

中国、ベトナム、インドのイネサンプルの地理的識別のための揮発性有機化合物のメタボロームフィンガープリンティング

Metabolomic fingerprinting of volatile organic compounds for the geographical discrimination of rice samples from China, Vietnam and India.
  • Ratnasekhar Ch
  • Olivier Chevallier
  • Philip McCarron
  • Terence F McGrath
  • Di Wu
  • Le Nguyen Doan Duy
  • Arun P Kapil
  • Mary McBride
  • Christopher T Elliott
  • Food Chem.2020 Jul;334:127553. S0308-8146(20)31415-1. doi: 10.1016/j.foodchem.2020.127553.Epub 2020-07-13.

シュワン細胞における乳酸トランスポーターMCT1の機能障害は、MCT4の機能障害ではなく、運動端板神経支配の維持に影響を与える

Disrupted function of lactate transporter MCT1, but not MCT4, in Schwann cells affects the maintenance of motor end-plate innervation.
  • Filipa Bouçanova
  • Gill Pollmeier
  • Katalin Sandor
  • Carlos Morado Urbina
  • Jik Nijssen
  • Jean-Jacques Médard
  • Luca Bartesaghi
  • Luc Pellerin
  • Camilla I Svensson
  • Eva Hedlund
  • Roman Chrast
  • Glia.2020 Jul;doi: 10.1002/glia.23889.Epub 2020-07-20.

焦点性皮質形成不全（FCD）と診断された成人および小児における亜急性新皮質刺激（SNCS）とそのてんかん活動への影響について検討した

Subacute neocortical stimulation (SNCS) and its effects on epileptic activity in adults and children diagnosed with focal cortical dysplasia (FCD).
  • Sascha Freigang
  • Diego Jiménez-Jiménez
  • Farhana Kazi
  • Judit Díaz-Díaz
  • Marisa Pina
  • Maria Cunha
  • Gonzalo Alarcón
  • Richard P Selway
  • Antonio Valentín
  • Epilepsy Res..2020 Jun;166:106392. S0920-1211(20)30205-9. doi: 10.1016/j.eplepsyres.2020.106392.Epub 2020-06-08.

魚油補給はLPSうつ病モデルにおいてインドレアミン-2,3-ジオキシゲナーゼの発現を減少させ、海馬のセロトニンレベルを増加させる

Fish-oil supplementation decreases Indoleamine-2,3-Dioxygenase expression and increases hippocampal serotonin levels in the LPS depression model.
  • Bruno Carabelli
  • Ana Márcia Delattre
  • Ana Paula Farias Waltrick
  • Giulia Araújo
  • Deborah Suchecki
  • Ricardo Borges Machado
  • Luiz Eduardo Rizzo de Souza
  • Silvio M Zanata
  • Janaína Menezes Zanoveli
  • Anete Curte Ferraz
  • Behav. Brain Res..2020 Jul;390:112675. S0166-4328(20)30374-0. doi: 10.1016/j.bbr.2020.112675.Epub 2020-05-12.

ヒトTリンパ球向性ウイルス1型（HTLV-1）、サイトメガロウイルス（CMV）、ストロンギロイデス・スターコラリスに感染した免疫抑制療法中の患者の死亡例：症例報告

Fatal outcome in a patient under immunosuppressant therapy infected with human T-lymphotropic virus type 1 (HTLV-1), cytomegalovirus (CMV) and Strongyloides stercoralis: a case report.
  • Chisato Ashida
  • Koji Kinoshita
  • Yuji Nozaki
  • Masanori Funauchi
  • BMC Infect. Dis..2020 Jul;20(1):470. 10.1186/s12879-020-05195-0. doi: 10.1186/s12879-020-05195-0.Epub 2020-07-02.

実世界の設定における学校ベースの身体活動および摂食行動介入の採用、実施、および持続可能性：システマティックレビュー

Adoption, implementation and sustainability of school-based physical activity and sedentary behaviour interventions in real-world settings: a systematic review.
  • Samuel Cassar
  • Jo Salmon
  • Anna Timperio
  • Patti-Jean Naylor
  • Femke van Nassau
  • Ana María Contardo Ayala
  • Harriet Koorts
  • Int J Behav Nutr Phys Act.2019 12;16(1):120. 10.1186/s12966-019-0876-4. doi: 10.1186/s12966-019-0876-4.Epub 2019-12-02.

デオキシイノシン含有オリゴヌクレオチドとエンドヌクレアーゼVを用いたランダム領域を含むフラグメントからの大規模DNAライブラリーの体外構築

In Vitro Construction of Large-scale DNA Libraries from Fragments Containing Random Regions using Deoxyinosine-containing Oligonucleotides and Endonuclease V.
  • Yasuhide Yamamoto
  • Takuya Terai
  • Shigefumi Kumachi
  • Naoto Nemoto
  • ACS Comb Sci.2020 04;22(4):165-171. doi: 10.1021/acscombsci.9b00167.Epub 2020-03-26.

ヒト・イヌ感染症の診断：組換え蛋白質を用いた間接酵素免疫吸着法の開発と評価

Diagnosis of human and canine infection: development and evaluation of indirect enzyme-linked immunosorbent assays using recombinant proteins.
  • Miryan Margot Sánchez-Jiménez
  • Juan Jacobo de la Cuesta Zuluaga
  • Gisela María Garcia-Montoya
  • Neha Dabral
  • Juan Fernando Alzate
  • Ramesh Vemulapalli
  • Martha Olivera-Angel
  • Heliyon.2020 Jul;6(7):e04393. S2405-8440(20)31237-8. doi: 10.1016/j.heliyon.2020.e04393.Epub 2020-07-11.

喉頭全摘出術後の扁平上皮癌の再発傍節切除後の気管および気管ストーム再建に対するIMAPプロペラフラップの有用性

The usefulness of the IMAP propeller flap for trachea and tracheostome reconstruction after resection of parastomal recurrence of squamous cell carcinoma following salvage total laryngectomy.
  • Giovanni Almadori
  • Giovanni Di Cintio
  • Eugenio De Corso
  • Dario Antonio Mele
  • Stefano Settimi
  • Aurora Almadori
  • Alessandro Cina
  • Giuseppe Visconti
  • Gaetano Paludetti
  • Marzia Salgarello
  • Eur Arch Otorhinolaryngol.2020 Jul;10.1007/s00405-020-06168-4. doi: 10.1007/s00405-020-06168-4.Epub 2020-07-01.

イネのペンタトリコペプチドリピートタンパク質PPR756は、ミトコンドリアにおける複数のRNA編集に影響を与えて花粉の発生に関与していることを明らかにした

The Rice Pentatricopeptide Repeat Protein PPR756 Is Involved in Pollen Development by Affecting Multiple RNA Editing in Mitochondria.
  • Qiannan Zhang
  • Yanghong Xu
  • Jishuai Huang
  • Kai Zhang
  • Haijun Xiao
  • Xiaojian Qin
  • Linlin Zhu
  • Yingguo Zhu
  • Jun Hu
  • Front Plant Sci.2020;11:749. doi: 10.3389/fpls.2020.00749.Epub 2020-06-12.

中国における汚染レベルの異なる酸性土壌中のトウモロコシカーネルのカドミウム蓄積特性を系統的に調査した

The systematic exploration of cadmium-accumulation characteristics of maize kernel in acidic soil with different pollution levels in China.
  • Lu Feng
  • Huili Yan
  • Changhua Dai
  • Wenxiu Xu
  • Fengying Gu
  • Fan Zhang
  • Ting Li
  • Jiayue Xian
  • Xiquan He
  • Yijun Yu
  • Mi Ma
  • Feng Wang
  • Zhenyan He
  • Sci. Total Environ..2020 Aug;729:138972. S0048-9697(20)32489-X. doi: 10.1016/j.scitotenv.2020.138972.Epub 2020-04-25.

に対する著者の反応。'への応答における編集者への手紙。"CYP2C9およびCYP2C19の多型が経口または経膣投与されたプロゲステロンの投薬、安全性および代謝に及ぼす影響」'

Author's Response to: 'Letter to the Editor in Response to: "Effect of Polymorphisms in CYP2C9 and CYP2C19 on the Disposition, Safety and Metabolism of Progesterone Administrated Orally or Vaginally"'.
  • Pablo Zubiaur
  • Miriam Saiz-Rodríguez
  • Francisco Abad-Santos
  • Adv Ther.2020 02;37(2):965-967. 10.1007/s12325-019-01196-x. doi: 10.1007/s12325-019-01196-x.Epub 2019-12-24.

二硫化モリブデンと金ナノ粒子を電子的に結合させ、過酸化水素と癌細胞の比色免疫測定のためのペルオキシダーゼ活性を向上させます

Electronic coupling between molybdenum disulfide and gold nanoparticles to enhance the peroxidase activity for the colorimetric immunoassays of hydrogen peroxide and cancer cells.
  • Haohao Sun
  • Yan Gao
  • Narisu Hu
  • Yongxia Zhang
  • Chongshen Guo
  • Guanggang Gao
  • Zhuo Ma
  • Krasnyuk Ivan Ivanovich
  • Yunfeng Qiu
  • J Colloid Interface Sci.2020 Jun;578:366-378. S0021-9797(20)30746-3. doi: 10.1016/j.jcis.2020.06.001.Epub 2020-06-06.

イネの OsSWEET14 の CRISPR/Cas9 媒介突然変異は、イネの抵抗性を高めることができた。Zhonghua11 の OsSWEET14 の CRISPR/Cas9 媒介変異は、収量のペナルティなしに Xanthomonas oryzae pv. oryzae への耐性を付与することができた

CRISPR/Cas9-mediated mutation of OsSWEET14 in rice cv. Zhonghua11 confers resistance to Xanthomonas oryzae pv. oryzae without yield penalty.
  • Xuan Zeng
  • Yufen Luo
  • Nga Thi Quynh Vu
  • Shujuan Shen
  • Kuaifei Xia
  • Mingyong Zhang
  • BMC Plant Biol..2020 Jul;20(1):313. 10.1186/s12870-020-02524-y. doi: 10.1186/s12870-020-02524-y.Epub 2020-07-03.

異性体ニコチン性アセチルコリン受容体に高い親和性を持つピロリジニルベンゾジオキサンとプロリノールアリールエーテルを投与したゼブラフィッシュの行動と薬理学的プロファイル

Behavioural and pharmacological profiles of zebrafish administrated pyrrolidinyl benzodioxanes and prolinol aryl ethers with high affinity for heteromeric nicotinic acetylcholine receptors.
  • Daniela Braida
  • Luisa Ponzoni
  • Milena Moretti
  • Paola Viani
  • Marco Pallavicini
  • Cristiano Bolchi
  • Rebecca Appiani
  • Francesco Bavo
  • Cecilia Gotti
  • Mariaelvina Sala
  • Psychopharmacology (Berl.).2020 Aug;237(8):2317-2326. 10.1007/s00213-020-05536-6. doi: 10.1007/s00213-020-05536-6.Epub 2020-05-07.

新規ホスホジエステラーゼ1阻害剤DSR-141562は、統合失調症に伴う陽性・陰性・認知症状に対して動物モデルで有効性を示しました

A Novel Phosphodiesterase 1 Inhibitor DSR-141562 Exhibits Efficacies in Animal Models for Positive, Negative, and Cognitive Symptoms Associated with Schizophrenia.
  • Takeshi Enomoto
  • Ayaka Tatara
  • Masao Goda
  • Yohei Nishizato
  • Kantaro Nishigori
  • Atsushi Kitamura
  • Mami Kamada
  • Shiori Taga
  • Takashi Hashimoto
  • Kazuhito Ikeda
  • Yuki Fujii
  • J. Pharmacol. Exp. Ther..2019 12;371(3):692-702. jpet.119.260869. doi: 10.1124/jpet.119.260869.Epub 2019-10-02.

治療計画のための構造ガイド付き変形画像登録と定位後体外放射線治療（SBRT）のためのプリモビスト（Gd-EOB-DTPA）強化MRI

Structure guided deformable image registration for treatment planning CT and post stereotactic body radiation therapy (SBRT) Primovist (Gd-EOB-DTPA) enhanced MRI.
  • Svetlana Kuznetsova
  • Petra Grendarova
  • Soumyajit Roy
  • Rishi Sinha
  • Kundan Thind
  • Nicolas Ploquin
  • J Appl Clin Med Phys.2019 Dec;20(12):109-118. doi: 10.1002/acm2.12773.Epub 2019-11-22.

COA6 は、ミトコンドリアのチトクロム c 酸化酵素に銅を供給する際に、チオール-ジスルフィド酸化還元酵素として機能するように構造的に調整されています

COA6 Is Structurally Tuned to Function as a Thiol-Disulfide Oxidoreductase in Copper Delivery to Mitochondrial Cytochrome c Oxidase.
  • Shivatheja Soma
  • Marcos N Morgada
  • Mandar T Naik
  • Aren Boulet
  • Anna A Roesler
  • Nathaniel Dziuba
  • Alok Ghosh
  • Qinhong Yu
  • Paul A Lindahl
  • James B Ames
  • Scot C Leary
  • Alejandro J Vila
  • Vishal M Gohil
  • Cell Rep.2019 12;29(12):4114-4126.e5. S2211-1247(19)31536-0. doi: 10.1016/j.celrep.2019.11.054.

前立腺癌におけるSULT2B1bスルホトランスフェラーゼとAKR1C3アルドケト還元酵素の阻害的相互作用の研究

Inhibitory Interplay of SULT2B1b Sulfotransferase with AKR1C3 Aldo-keto Reductase in Prostate Cancer.
  • Sulgi Park
  • Chung-Seog Song
  • Chun-Lin Lin
  • Shoulei Jiang
  • Pawel A Osmulski
  • Chiou-Miin Wang
  • Brett T Marck
  • Alvin M Matsumoto
  • Colm Morrissey
  • Maria E Gaczynska
  • Yidong Chen
  • Elahe A Mostaghel
  • Bandana Chatterjee
  • Endocrinology.2020 02;161(2). bqz042. doi: 10.1210/endocr/bqz042.

低酸素性虚血性脳症は、心停止後の脳解剖および神経プロトグノスチーショ ンにより評価された

Hypoxic-Ischemic Encephalopathy Evaluated by Brain Autopsy and Neuroprognostication After Cardiac Arrest.
  • Christian Endisch
  • Erik Westhall
  • Martin Kenda
  • Kaspar J Streitberger
  • Hans Kirkegaard
  • Werner Stenzel
  • Christian Storm
  • Christoph J Ploner
  • Tobias Cronberg
  • Hans Friberg
  • Elisabet Englund
  • Christoph Leithner
  • JAMA Neurol.2020 Jul;2768384. doi: 10.1001/jamaneurol.2020.2340.Epub 2020-07-20.

GP130サイトカイン受容体シグナルの欠乏は、拡張シュトゥヴェ・ヴィーデマン症候群を引き起こす

Absence of GP130 cytokine receptor signaling causes extended Stüve-Wiedemann syndrome.
  • Yin-Huai Chen
  • Giedre Grigelioniene
  • Phillip T Newton
  • Jacob Gullander
  • Maria Elfving
  • Anna Hammarsjö
  • Dominyka Batkovskyte
  • Hessa S Alsaif
  • Wesam I Y Kurdi
  • Firdous Abdulwahab
  • Veerabahu Shanmugasundaram
  • Luke Devey
  • Séverine Bacrot
  • Jana Brodszki
  • Celine Huber
  • Ben Hamel
  • David Gisselsson
  • Nikos Papadogiannakis
  • Katarina Jedrycha
  • Barbara Gürtl-Lackner
  • Andrei S Chagin
  • Gen Nishimura
  • Dominik Aschenbrenner
  • Fowzan S Alkuraya
  • Arian Laurence
  • Valérie Cormier-Daire
  • Holm H Uhlig
  • J. Exp. Med..2020 Mar;217(3). e20191306. doi: 10.1084/jem.20191306.

古細菌のRNA処理機械：β-CASPファミリーの5'-3'エキソリボヌクレアーゼaRNase Jは、ヘリカーゼASH-Ski2と3'-5'エキソリボヌクレアーゼRNAエキソソソーム機械に特異的に関与している

RNA processing machineries in Archaea: the 5'-3' exoribonuclease aRNase J of the β-CASP family is engaged specifically with the helicase ASH-Ski2 and the 3'-5' exoribonucleolytic RNA exosome machinery.
  • Duy Khanh Phung
  • Clarisse Etienne
  • Manon Batista
  • Petra Langendijk-Genevaux
  • Yann Moalic
  • Sébastien Laurent
  • Sophie Liuu
  • Violette Morales
  • Mohamed Jebbar
  • Gwennaele Fichant
  • Marie Bouvier
  • Didier Flament
  • Béatrice Clouet-d'Orval
  • Nucleic Acids Res..2020 04;48(7):3832-3847. 5728875. doi: 10.1093/nar/gkaa052.

呑み込みから豊かさへ：メイヤー・ロキタンスキー・キュスター・ハウザー症候群における病気の表象、自己概念、心理的適応との関連

From engulfment to enrichment: associations between illness representations, self-concept and psychological adjustment in Mayer-Rokitansky-Küster-Hauser Syndrome.
  • Susan Carroll
  • Marc Laufer
  • Phaedra Thomas-Kowal
  • Amy C Lossie
  • Rona Moss-Morris
  • J Pediatr Adolesc Gynecol.2020 Jul;S1083-3188(20)30282-5. doi: 10.1016/j.jpag.2020.07.006.Epub 2020-07-17.

マルチングを用いたドリップ灌漑下で栽培されたトウモロコシにおけるバイオ炭の温室効果ガス排出量と土壌炭素貯留量への影響（英文

Impact of biochar on greenhouse gas emissions and soil carbon sequestration in corn grown under drip irrigation with mulching.
  • Wei Yang
  • Gary Feng
  • Dana Miles
  • Lihua Gao
  • Yonglin Jia
  • Changjian Li
  • Zhongyi Qu
  • Sci. Total Environ..2020 Aug;729:138752. S0048-9697(20)32269-5. doi: 10.1016/j.scitotenv.2020.138752.Epub 2020-04-17.

COVID-19治療薬であるロピナビル/リトナビル内服液のICU患者を対象とした薬物動態解析

Pharmacokinetics of lopinavir/ritonavir oral solution to treat COVID-19 in mechanically ventilated ICU patients.
  • Minh Patrick Lê
  • Pierre Jaquet
  • Juliette Patrier
  • Paul-Henri Wicky
  • Quentin Le Hingrat
  • Marc Veyrier
  • Juliette Kauv
  • Romain Sonneville
  • Benoit Visseaux
  • Cédric Laouénan
  • Lila Bouadma
  • Diane Descamps
  • Etienne de Montmollin
  • Gilles Peytavin
  • Jean-François Timsit
  • J. Antimicrob. Chemother..2020 Jul;dkaa261. doi: 10.1093/jac/dkaa261.Epub 2020-07-20.

胚性神経幹/前駆細胞の分化過程におけるジストロフィンおよびジストロフィン関連タンパク質の発現の解析

Characterization of the expression of dystrophins and dystrophin-associated proteins during embryonic neural stem/progenitor cell differentiation.
  • José Romo-Yáñez
  • Griselda Rodríguez-Martínez
  • Jorge Aragón
  • Lourdes Siqueiros-Márquez
  • Alma Herrera-Salazar
  • Iván Velasco
  • Cecilia Montanez
  • Neurosci. Lett..2020 Jul;:135247. S0304-3940(20)30517-6. doi: 10.1016/j.neulet.2020.135247.Epub 2020-07-12.

アレルギー性炎症は急性心筋梗塞後の冠動脈の不安定性と臨床成績の悪化と関連している

Allergic Inflammation Is Associated With Coronary Instability and a Worse Clinical Outcome After Acute Myocardial Infarction.
  • Giampaolo Niccoli
  • Camilla Calvieri
  • Davide Flego
  • Giancarla Scalone
  • Asya Imaeva
  • Vito Sabato
  • Domenico Schiavino
  • Giovanna Liuzzo
  • Filippo Crea
  • Circ Cardiovasc Interv.2015 Aug;8(8):e002554. CIRCINTERVENTIONS.115.002554. doi: 10.1161/CIRCINTERVENTIONS.115.002554.

気候は、紀元前6,100年から紀元前4,500年までの間に、新石器時代の農民とヨーロッパの狩猟採集民の交流をどのように形成したかを示している

Climate shaped how Neolithic farmers and European hunter-gatherers interacted after a major slowdown from 6,100 BCE to 4,500 BCE.
  • Lia Betti
  • Robert M Beyer
  • Eppie R Jones
  • Anders Eriksson
  • Francesca Tassi
  • Veronika Siska
  • Michela Leonardi
  • Pierpaolo Maisano Delser
  • Lily K Bentley
  • Philip R Nigst
  • Jay T Stock
  • Ron Pinhasi
  • Andrea Manica
  • Nat Hum Behav.2020 Jul;10.1038/s41562-020-0897-7. doi: 10.1038/s41562-020-0897-7.Epub 2020-07-06.

従来および手作りのクローニング技術と体外および生体内で成熟した卵子を用いて生産されたクローン化されたドロメダリーラクダの妊娠率および分娩率

Pregnancy and Calving Rates of Cloned Dromedary Camels Produced by Conventional and Handmade Cloning Techniques and In Vitro and In Vivo Matured Oocytes.
  • F Moulavi
  • B Asadi-Moghadam
  • M Omidi
  • M Yarmohammadi
  • M Ozegovic
  • A Rastegar
  • S M Hosseini
  • Mol. Biotechnol..2020 Jul;10.1007/s12033-020-00262-y. doi: 10.1007/s12033-020-00262-y.Epub 2020-07-14.

新規精神活性物質である25C-NBFは、げっ歯類では中毒性と神経毒の可能性を持っています

25C-NBF, a new psychoactive substance, has addictive and neurotoxic potential in rodents.
  • Kwang-Hyun Hur
  • Seong-Eon Kim
  • Bo-Ram Lee
  • Yong-Hyun Ko
  • Jee-Yeon Seo
  • Seon-Kyung Kim
  • Shi-Xun Ma
  • Young-Jung Kim
  • Yeongdo Jeong
  • Duc Toan Pham
  • Quynh Dieu Trinh
  • Eun-Joo Shin
  • Hyoung-Chun Kim
  • Yong-Sup Lee
  • Seok-Yong Lee
  • Choon-Gon Jang
  • Arch. Toxicol..2020 Jul;94(7):2505-2516. 10.1007/s00204-020-02740-3. doi: 10.1007/s00204-020-02740-3.Epub 2020-04-15.

矯正施設および拘置施設の投獄者および拘禁者における SARS-CoV-2 感染のための連続検査 - ルイジアナ州、2020 年 4 月～5 月

Serial Laboratory Testing for SARS-CoV-2 Infection Among Incarcerated and Detained Persons in a Correctional and Detention Facility - Louisiana, April-May 2020.
  • Henry Njuguna
  • Megan Wallace
  • Sean Simonson
  • Farrell A Tobolowsky
  • Allison E James
  • Keith Bordelon
  • Rena Fukunaga
  • Jeremy A W Gold
  • Jonathan Wortham
  • Theresa Sokol
  • Danielle Haydel
  • Ha Tran
  • Kaylee Kim
  • Kiva A Fisher
  • Mariel Marlow
  • Jacqueline E Tate
  • Reena H Doshi
  • Kathryn G Curran
  • MMWR Morb. Mortal. Wkly. Rep..2020 Jul;69(26):836-840. doi: 10.15585/mmwr.mm6926e2.Epub 2020-07-03.

カルボプラチンおよびパクリタキセルによる治療を受けた上皮性卵巣がん患者（ベバシズマブ併用または非併用）における血液ベースのバイオマーカーの予測。GOG-0218の結果

Predictive Blood-Based Biomarkers in Patients with Epithelial Ovarian Cancer Treated with Carboplatin and Paclitaxel with or without Bevacizumab: Results from GOG-0218.
  • Angeles Alvarez Secord
  • Kirsten Bell Burdett
  • Kouros Owzar
  • David Tritchler
  • Alexander B Sibley
  • Yingmiao Liu
  • Mark D Starr
  • J Chris Brady
  • Heather A Lankes
  • Herbert I Hurwitz
  • Robert S Mannel
  • Krishnansu S Tewari
  • David M O'Malley
  • Heidi Gray
  • Jamie N Bakkum-Gamez
  • Keiichi Fujiwara
  • Matthew Boente
  • Wei Deng
  • Robert A Burger
  • Michael J Birrer
  • Andrew B Nixon
  • Clin. Cancer Res..2020 Mar;26(6):1288-1296. 1078-0432.CCR-19-0226. doi: 10.1158/1078-0432.CCR-19-0226.Epub 2020-01-09.

ブラジル中央部の若い遺伝性色素性乾皮症クラスターへのイベリアの遺産

The Iberian legacy into a young genetic xeroderma pigmentosum cluster in central Brazil.
  • L P Castro
  • M Sahbatou
  • F S G Kehdy
  • A A Farias
  • A A Yurchenko
  • T A de Souza
  • R C A Rosa
  • C T Mendes-Junior
  • V Borda
  • V Munford
  • É A Zanardo
  • S N Chehimi
  • L D Kulikowski
  • M M Aquino
  • T P Leal
  • E Tarazona-Santos
  • S C Chaibub
  • B Gener
  • N Calmels
  • V Laugel
  • A Sarasin
  • C F M Menck
  • Mutat. Res..2020 04;852:503164. S1383-5718(20)30034-6. doi: 10.1016/j.mrgentox.2020.503164.Epub 2020-02-29.

バイオガス消化物とバイオ炭でミネラル肥料を置換すると、物理的に安定化した土壌炭素は増加するが、作物のバイオマスは増加しない

Substitution of mineral fertilizers with biogas digestate plus biochar increases physically stabilized soil carbon but not crop biomass in a field trial.
  • Isabel Greenberg
  • Michael Kaiser
  • Anna Gunina
  • Philipp Ledesma
  • Steven Polifka
  • Katja Wiedner
  • Carsten W Mueller
  • Bruno Glaser
  • Bernard Ludwig
  • Sci. Total Environ..2019 Aug;680:181-189. S0048-9697(19)32062-5. doi: 10.1016/j.scitotenv.2019.05.051.Epub 2019-05-06.

小児低悪性度神経膠腫における反応性評価：小児神経腫瘍学における反応性評価（RAPNO）ワーキンググループの推奨事項

Response assessment in paediatric low-grade glioma: recommendations from the Response Assessment in Pediatric Neuro-Oncology (RAPNO) working group.
  • Jason Fangusaro
  • Olaf Witt
  • Pablo Hernáiz Driever
  • Asim K Bag
  • Peter de Blank
  • Nadja Kadom
  • Lindsay Kilburn
  • Robert M Lober
  • Nathan J Robison
  • Michael J Fisher
  • Roger J Packer
  • Tina Young Poussaint
  • Ludmila Papusha
  • Shivaram Avula
  • Alba A Brandes
  • Eric Bouffet
  • Daniel Bowers
  • Anton Artemov
  • Murali Chintagumpala
  • David Zurakowski
  • Martin van den Bent
  • Brigitte Bison
  • Kristen W Yeom
  • Walter Taal
  • Katherine E Warren
  • Lancet Oncol..2020 06;21(6):e305-e316. S1470-2045(20)30064-4. doi: 10.1016/S1470-2045(20)30064-4.

肝線維症のバイオマーカー：マルチモーダル磁気共鳴、血清アルゴリズム、一過性エラストグラフィの前向き比較

Biomarkers of liver fibrosis: prospective comparison of multimodal magnetic resonance, serum algorithms and transient elastography.
  • Mikael F Forsgren
  • Patrik Nasr
  • Markus Karlsson
  • Nils Dahlström
  • Bengt Norén
  • Simone Ignatova
  • Ralph Sinkus
  • Gunnar Cedersund
  • Olof Dahlqvist Leinhard
  • Mattias Ekstedt
  • Stergios Kechagias
  • Peter Lundberg
  • Scand. J. Gastroenterol..2020 Jul;:1-12. doi: 10.1080/00365521.2020.1786599.Epub 2020-07-20.

局所進行乳癌における全生存期間予測のための造影MRIによるテクスチャー特徴の有用性

Feasibility of contrast-enhanced MRI derived textural features to predict overall survival in locally advanced breast cancer.
  • Ioanna Chronaiou
  • Guro Fanneløb Giskeødegård
  • Pål Erik Goa
  • Jose Teruel
  • Roja Hedayati
  • Steinar Lundgren
  • Else Marie Huuse
  • Martin D Pickles
  • Peter Gibbs
  • Beathe Sitter
  • Tone Frost Bathen
  • Acta Radiol.2020 Jul;61(7):875-884. doi: 10.1177/0284185119885116.Epub 2019-11-19.

シロイヌナズナのAtRsgAは葉緑体リボソームのスモールサブユニットの成熟に重要な役割を果たしている

AtRsgA from Arabidopsis thaliana is important for maturation of the small subunit of the chloroplast ribosome.
  • Marcin Janowski
  • Reimo Zoschke
  • Lars B Scharff
  • Silvia Martinez Jaime
  • Camilla Ferrari
  • Sebastian Proost
  • Jonathan Ng Wei Xiong
  • Nooshin Omranian
  • Magdalena Musialak-Lange
  • Zoran Nikoloski
  • Alexander Graf
  • Mark A Schöttler
  • Arun Sampathkumar
  • Neha Vaid
  • Marek Mutwil
  • Plant J..2018 10;96(2):404-420. doi: 10.1111/tpj.14040.Epub 2018-09-08.

体外受精中の短期的な温度上昇は胚の収量に影響を与え、ウシの卵母細胞、積体細胞、胚盤胞の遺伝子発現パターンを変化させる

Short term temperature elevation during IVM affects embryo yield and alters gene expression pattern in oocytes, cumulus cells and blastocysts in cattle.
  • Konstantina Stamperna
  • Themistoklis Giannoulis
  • Ioannis Nanas
  • Maria Kalemkeridou
  • Katerina Dadouli
  • Katerina Moutou
  • Georgios S Amiridis
  • Eleni Dovolou
  • Theriogenology.2020 Jun;156:36-45. S0093-691X(20)30390-3. doi: 10.1016/j.theriogenology.2020.06.039.Epub 2020-06-30.

CD8およびCD163免疫細胞の密度と空間的な組織分布は、MAPK阻害薬を投与されたメラノーマ患者における反応と転帰を予測する

The density and spatial tissue distribution of CD8 and CD163 immune cells predict response and outcome in melanoma patients receiving MAPK inhibitors.
  • Daniela Massi
  • Eliana Rulli
  • Mara Cossa
  • Barbara Valeri
  • Monica Rodolfo
  • Barbara Merelli
  • Francesco De Logu
  • Romina Nassini
  • Michele Del Vecchio
  • Lorenza Di Guardo
  • Roberta De Penni
  • Michele Guida
  • Vanna Chiarion Sileni
  • Anna Maria Di Giacomo
  • Marco Tucci
  • Marcella Occelli
  • Francesca Portelli
  • Viviana Vallacchi
  • Francesca Consoli
  • Pietro Quaglino
  • Paola Queirolo
  • Gianna Baroni
  • Fabrizio Carnevale-Schianca
  • Laura Cattaneo
  • Alessandro Minisini
  • Giuseppe Palmieri
  • Licia Rivoltini
  • Mario Mandalà
  • J Immunother Cancer.2019 11;7(1):308. 10.1186/s40425-019-0797-4. doi: 10.1186/s40425-019-0797-4.Epub 2019-11-15.

中性ステロイドの分析を容易にするための高分子/界面活性剤複合体のインキャピラリー形成-アシスト逆マイグレーションミセル電気泳動クロマトグラフィーの開発

In-capillary formation of polymer/surfactant complexes-assisted reversed-migration micellar electrokinetic chromatography for facile analysis of neutral steroids.
  • Li-Chen Wu
  • Ching-Yuan Hu
  • Yi-Shiou Dung
  • Tsung-Hung Wu
  • Talanta.2013 Mar;107:389-95. S0039-9140(13)00046-5. doi: 10.1016/j.talanta.2013.01.036.Epub 2013-02-04.

トラマドール曝露は、PC12細胞とラットの線条体において、アポトーシス、炎症、オートファジーを増加させた：in vitro-in vivoアプローチ

Tramadol exposure upregulated apoptosis, inflammation and autophagy in PC12 cells and rat's striatum: An in vitro- in vivo approach.
  • Reza Soltani
  • Mahdi Eskandarian Boroujeni
  • Fakhroddin Aghajanpour
  • Aysan Khatmi
  • Samira Ezi
  • Seyed Hamidreza Mirbehbahani
  • Mohammad-Amin Abdollahifar
  • Mohamadhosein Akhlaghpasand
  • Abbas Aliaghaei
  • Mohammad-Hasan Heidari
  • J. Chem. Neuroanat..2020 Jun;109:101820. S0891-0618(20)30089-2. doi: 10.1016/j.jchemneu.2020.101820.Epub 2020-06-08.

The Dysphagia in Multiple Sclerosis Questionnaire Correlates with Fiber-Optic Endoscopic Examination for Detecting Defits in MS

The Dysphagia in Multiple Sclerosis Questionnaire Correlates with Fiber-Optic Endoscopic Examination for Detecting Swallowing Deficits in MS.
  • Maria Grazia Grasso
  • Giulia Gamberini
  • Francesco Patti
  • Emanuele D'Amico
  • Roberto Bergamaschi
  • Eliana Berra
  • Antonella Giusti
  • Alessandro Cuccaro
  • Michele Messmer Uccelli
  • Claudio Solaro
  • Dysphagia.2020 Apr;10.1007/s00455-020-10119-w. doi: 10.1007/s00455-020-10119-w.Epub 2020-04-30.

秦嶺（中国）の腐った木材からのバイオマス分解のためのセルロース分解菌のスクリーニングとBacillus methylotrophicusからのセルラーゼのクローニング

Screening of cellulolytic bacteria from rotten wood of Qinling (China) for biomass degradation and cloning of cellulases from Bacillus methylotrophicus.
  • Lingling Ma
  • Yingying Lu
  • Hong Yan
  • Xin Wang
  • Yanglei Yi
  • Yuanyuan Shan
  • Bianfang Liu
  • Yuan Zhou
  • Xin Lü
  • BMC Biotechnol..2020 01;20(1):2. 10.1186/s12896-019-0593-8. doi: 10.1186/s12896-019-0593-8.Epub 2020-01-07.

統合失調症と遺伝的ハイリスク者における構造的連結性とサイトカインレベルの変化。病態や脆弱性との関連

Altered structural connectivity and cytokine levels in Schizophrenia and Genetic high-risk individuals: Associations with disease states and vulnerability.
  • Yang Wang
  • Yange Wei
  • E Kale Edmiston
  • Fay Y Womer
  • Xizhe Zhang
  • Jia Duan
  • Yue Zhu
  • Ran Zhang
  • Zhiyang Yin
  • Yifan Zhang
  • Xiaowei Jiang
  • Shengnan Wei
  • Zhuang Liu
  • Yanbo Zhang
  • Yanqing Tang
  • Fei Wang
  • Schizophr. Res..2020 Jul;S0920-9964(20)30298-X. doi: 10.1016/j.schres.2020.05.044.Epub 2020-07-16.

セコン県ラオスにおける高病原性鳥インフルエンザの検出 2018-風土病地域におけるサーベイランスと管理の改善の可能性

Detection of highly pathogenic avian influenza in Sekong Province Lao PDR 2018-Potential for improved surveillance and management in endemic regions.
  • Edward J Annand
  • Holly High
  • Frank Y K Wong
  • Phouvong Phommachanh
  • Chintana Chanthavisouk
  • Jonathan Happold
  • Madhur S Dhingra
  • Debbie Eagles
  • Philip N Britton
  • Robyn G Alders
  • Transbound Emerg Dis.2020 Jul;doi: 10.1111/tbed.13673.Epub 2020-07-19.

アルカディア/RNF111は、SUMO1で覆われたSUMO2/3鎖を持つ基質を好むSUMO標的ユビキチンリガーゼである

Arkadia/RNF111 is a SUMO-targeted ubiquitin ligase with preference for substrates marked with SUMO1-capped SUMO2/3 chain.
  • Annie M Sriramachandran
  • Katrin Meyer-Teschendorf
  • Stefan Pabst
  • Helle D Ulrich
  • Niels H Gehring
  • Kay Hofmann
  • Gerrit J K Praefcke
  • R Jürgen Dohmen
  • Nat Commun.2019 08;10(1):3678. 10.1038/s41467-019-11549-3. doi: 10.1038/s41467-019-11549-3.Epub 2019-08-15.

造血幹細胞老化と心筋修復 - RCT PERFECT Phase 3におけるCABG/CD133+骨髄造血幹細胞治療により誘発される心筋梗塞後の心筋再生反応の冠動脈疾患遺伝子型/フェノタイプ解析

Hematopoietic stem-cell senescence and myocardial repair - Coronary artery disease genotype/phenotype analysis of post-MI myocardial regeneration response induced by CABG/CD133+ bone marrow hematopoietic stem cell treatment in RCT PERFECT Phase 3.
  • Markus Wolfien
  • Denise Klatt
  • Amankeldi A Salybekov
  • Masaaki Ii
  • Miki Komatsu-Horii
  • Ralf Gaebel
  • Julia Philippou-Massier
  • Eric Schrinner
  • Hiroshi Akimaru
  • Erika Akimaru
  • Robert David
  • Jens Garbade
  • Jan Gummert
  • Axel Haverich
  • Holger Hennig
  • Hiroto Iwasaki
  • Alexander Kaminski
  • Atsuhiko Kawamoto
  • Christian Klopsch
  • Johannes T Kowallick
  • Stefan Krebs
  • Julia Nesteruk
  • Hermann Reichenspurner
  • Christian Ritter
  • Christof Stamm
  • Ayumi Tani-Yokoyama
  • Helmut Blum
  • Olaf Wolkenhauer
  • Axel Schambach
  • Takayuki Asahara
  • Gustav Steinhoff
  • EBioMedicine.2020 Jul;57:102862. S2352-3964(20)30237-1. doi: 10.1016/j.ebiom.2020.102862.Epub 2020-07-03.

M1APの二項対立型変異は、減数分裂停止と男性不妊につながる重度の造精障害の頻度の高い原因であることが明らかになった

Bi-allelic Mutations in M1AP Are a Frequent Cause of Meiotic Arrest and Severely Impaired Spermatogenesis Leading to Male Infertility.
  • Margot J Wyrwoll
  • Şehime G Temel
  • Liina Nagirnaja
  • Manon S Oud
  • Alexandra M Lopes
  • Godfried W van der Heijden
  • James S Heald
  • Nadja Rotte
  • Joachim Wistuba
  • Marius Wöste
  • Susanne Ledig
  • Henrike Krenz
  • Roos M Smits
  • Filipa Carvalho
  • João Gonçalves
  • Daniela Fietz
  • Burcu Türkgenç
  • Mahmut C Ergören
  • Murat Çetinkaya
  • Murad Başar
  • Semra Kahraman
  • Kevin McEleny
  • Miguel J Xavier
  • Helen Turner
  • Adrian Pilatz
  • Albrecht Röpke
  • Martin Dugas
  • Sabine Kliesch
  • Nina Neuhaus
  • Kenneth I Aston
  • Donald F Conrad
  • Joris A Veltman
  • Corinna Friedrich
  • Frank Tüttelmann
  • Am. J. Hum. Genet..2020 Jul;S0002-9297(20)30198-1. doi: 10.1016/j.ajhg.2020.06.010.Epub 2020-07-09.

RNA-seqに基づいた比較アプローチにより、3'-to-5' エキソRNaseとRNase Yの間のトランスクリプトームワイドな相互作用が明らかになった

An RNA-seq based comparative approach reveals the transcriptome-wide interplay between 3'-to-5' exoRNases and RNase Y.
  • Laura Broglia
  • Anne-Laure Lécrivain
  • Thibaud T Renault
  • Karin Hahnke
  • Rina Ahmed-Begrich
  • Anaïs Le Rhun
  • Emmanuelle Charpentier
  • Nat Commun.2020 03;11(1):1587. 10.1038/s41467-020-15387-6. doi: 10.1038/s41467-020-15387-6.Epub 2020-03-27.

p53変異マウスのクリプトクロム欠失は、トランスクリプトームレベルで紫外線損傷に対するアポトーシスおよび抗腫瘍反応を増強する

Cryptochrome deletion in p53 mutant mice enhances apoptotic and anti-tumorigenic responses to UV damage at the transcriptome level.
  • Ayse Derya Cavga
  • Mehmet Tardu
  • Tuba Korkmaz
  • Ozlem Keskin
  • Nuri Ozturk
  • Attila Gursoy
  • Ibrahim Halil Kavakli
  • Funct. Integr. Genomics.2019 Sep;19(5):729-742. 10.1007/s10142-019-00680-5. doi: 10.1007/s10142-019-00680-5.Epub 2019-05-01.

コリンエステラーゼとプロリルオリゴペプチダーゼをバランスよく阻害する新規ベルベリン誘導体の発見

Discovery of novel berberine derivatives with balanced cholinesterase and prolyl oligopeptidase inhibition profile.
  • Katerina Sobolova
  • Martina Hrabinova
  • Vendula Hepnarova
  • Tomas Kucera
  • Tereza Kobrlova
  • Marketa Benkova
  • Jana Janockova
  • Rafael Dolezal
  • Lukas Prchal
  • Ondrej Benek
  • Eva Mezeiova
  • Daniel Jun
  • Ondrej Soukup
  • Jan Korabecny
  • Eur J Med Chem.2020 Jul;203:112593. S0223-5234(20)30565-1. doi: 10.1016/j.ejmech.2020.112593.Epub 2020-07-15.

イネ科コイのcAMP依存性プロテインキナーゼA.小胞体ストレスによる脂肪分解における分子特性、遺伝子構造、組織分布、mRNA発現

cAMP-dependent protein kinase A in grass carp Ctenopharyngodon idella: Molecular characterization, gene structure, tissue distribution and mRNA expression in endoplasmic reticulum stress-induced adipocyte lipolysis.
  • Shanghong Ji
  • Jian Sun
  • ChenChen Bian
  • Xiaocheng Huang
  • Zhiguang Chang
  • Minghui Yang
  • Rong-Hua Lu
  • Hong Ji
  • Comp. Biochem. Physiol. B, Biochem. Mol. Biol..2020 Jul;:110479. S1096-4959(20)30073-7. doi: 10.1016/j.cbpb.2020.110479.Epub 2020-07-17.

静脈内血栓溶解療法が禁忌または失敗した患者を含む脳卒中血栓摘出術の評価：2つの新しい血栓摘出装置の無作為化試験

Evaluation of stroke thrombectomy including patients where IV thrombolysis is contraindicated or has failed: a randomized trial of two novel thrombectomy devices.
  • Philip M White
  • Barbara Gregson
  • Elena Adela Cora
  • Anand Dixit
  • Ganesh Subramanian
  • Yogish Joshi
  • Robert Simister
  • Rachel Lakey
  • Ahmed Maiter
  • Gary A Ford
  • J Neurointerv Surg.2020 Jul;neurintsurg-2020-016038. doi: 10.1136/neurintsurg-2020-016038.Epub 2020-07-14.

In Vitro Activity of Imipenem/Relebactam Against Gram-Negative Bacilli from Pediatric Patients-Study for Monitoring Antimicrobial Resistance Trends（SMART）グローバルサーベイランスプログラム2015-2017

In Vitro Activity of Imipenem/Relebactam Against Gram-Negative Bacilli from Pediatric Patients-Study for Monitoring Antimicrobial Resistance Trends (SMART) global surveillance program 2015-2017.
  • James A Karlowsky
  • Sibylle H Lob
  • Katherine Young
  • Mary R Motyl
  • Daniel F Sahm
  • J Pediatric Infect Dis Soc.2020 Jun;piaa056. doi: 10.1093/jpids/piaa056.Epub 2020-06-14.

に返信します。"SORAMIC試験における毒性と線量評価"Y90ラジオ塞栓療法は腫瘍の線量よりも肝機能の温存を重視しています。SIRTはTACEで採用されているような選択的技術を模倣すべきである

Reply to: "Toxicity and dosimetry in SORAMIC study": Y90 radioembolization is less about tumor dose, but preserving liver function: SIRT should mimic selective techniques as employed in TACE.
  • Jens Ricke
  • Bruno Sangro
  • Peter Malfertheiner
  • Max Seidensticker
  • Andrei Todica
  • J. Hepatol..2020 Jul;S0168-8278(20)30346-9. doi: 10.1016/j.jhep.2020.05.027.Epub 2020-07-08.

廃水から直接青78染料を除去するためのツールとしての卵副産物。運動論、平衡モデリング、熱力学、および脱離特性

Egg By-Products as a Tool to Remove Direct Blue 78 Dye from Wastewater: Kinetic, Equilibrium Modeling, Thermodynamics and Desorption Properties.
  • Ainoa Murcia-Salvador
  • José A Pellicer
  • María Isabel Rodríguez-López
  • Vicente Manuel Gómez-López
  • Estrella Núñez-Delicado
  • José A Gabaldón
  • Materials (Basel).2020 Mar;13(6). E1262. doi: 10.3390/ma13061262.Epub 2020-03-11.

プロバイオティクスは早産・低出生体重児の死亡率と罹患率を低下させる：無作為化試験のシステマティックレビューとネットワークメタアナリシス

Probiotics Reduce Mortality and Morbidity in Preterm, Low Birth Weight Infants: a Systematic Review and Network Meta-analysis of Randomized Trials.
  • Rebecca L Morgan
  • Geoffrey A Preidis
  • Purna C Kashyap
  • Adam V Weizman
  • Behnam Sadeghirad
  • Yaping Chang
  • Ivan D Florez
  • Farid Foroutan
  • Shaneela Shahid
  • Dena Zeraatkar
  • Gastroenterology.2020 Jun;S0016-5085(20)34849-6. doi: 10.1053/j.gastro.2020.05.096.Epub 2020-06-24.

β-ヒドロキシ酪酸デヒドロゲナーゼで装飾したMXeneナノシートを用いたβ-ヒドロキシ酪酸のアンペロメトリック測定のためのバイオセンサー

β-Hydroxybutyrate dehydrogenase decorated MXene nanosheets for the amperometric determination of β-hydroxybutyrate.
  • Aneesh Koyappayil
  • Sachin Ganpat Chavan
  • Mohsen Mohammadniaei
  • Anna Go
  • Sei Young Hwang
  • Min-Ho Lee
  • Mikrochim Acta.2020 04;187(5):277. 10.1007/s00604-020-04258-y. doi: 10.1007/s00604-020-04258-y.Epub 2020-04-20.

ブラジル人のサンプルにおける自己申告による口臭。有病率、関連するリスク予測因子および臨床診断の精度推定

Self-reported halitosis in a sample of Brazilians: Prevalence, associated risk predictors and accuracy estimates with clinical diagnosis.
  • Sandro Felipe Santos Faria
  • Fernando Oliveira Costa
  • Juliana Oliveira Silveira
  • Renata Magalhães Cyrino
  • Luís Otávio Miranda Cota
  • J. Clin. Periodontol..2020 Feb;47(2):233-246. doi: 10.1111/jcpe.13226.Epub 2019-12-23.

短縮通信。デンプンとコーン油、海藻類、または水添パーム油を補った食事は、牛とヤギの乳中の特定の代謝物濃度に異なる影響を与える

Short communication: Diets supplemented with starch and corn oil, marine algae, or hydrogenated palm oil differently affect selected metabolite concentrations in cow and goat milk.
  • L Bernard
  • H Fougère
  • T Larsen
  • J Pires
  • J. Dairy Sci..2020 Jun;103(6):5647-5653. S0022-0302(20)30291-5. doi: 10.3168/jds.2019-18008.Epub 2020-04-16.

新規に単離されたAspergillus terreus (KUBCF1306)からのβ-ガラクトシダーゼの精製と特性評価、および乳癌細胞株(MCF-7)におけるその有効性の評価

Purification and characterization of β-galactosidase from newly isolated Aspergillus terreus (KUBCF1306) and evaluating its efficacy on breast cancer cell line (MCF-7).
  • B Vidya
  • M Palaniswamy
  • J Angayarkanni
  • K Ayub Nawaz
  • M Thandeeswaran
  • K Krishna Chaithanya
  • Berihu Tekluu
  • Karthi Muthusamy
  • V K Gopalakrishnan
  • Bioorg. Chem..2020 Jan;94:103442. S0045-2068(19)31027-2. doi: 10.1016/j.bioorg.2019.103442.Epub 2019-11-15.

多発性硬化症患者における機能的能力、等脚力、睡眠の質、認知機能との関連：横断的研究

Associations between functional capacity, isokinetic leg strength, sleep quality and cognitive function in multiple sclerosis patients: a cross-sectional study.
  • Panayiotis Aristotelous
  • Manos Stefanakis
  • Marios Pantzaris
  • Constantinos Pattichis
  • Georgios M Hadjigeorgiou
  • Christoforos D Giannaki
  • Postgrad Med.2019 Sep;131(7):453-460. doi: 10.1080/00325481.2019.1662271.Epub 2019-10-01.

逆流性大伏在静脈の治療のためのシアノアクリレート塞栓術に関する前向きなヨーロッパ多施設コホート研究の3年間の追跡調査結果

Three-year follow-up results of the prospective European Multicenter Cohort Study on Cyanoacrylate Embolization for treatment of refluxing great saphenous veins.
  • Thomas Proebstle
  • Jens Alm
  • Sameh Dimitri
  • Lars Rasmussen
  • Mark Whiteley
  • James Lawson
  • Alun Huw Davies
  • J Vasc Surg Venous Lymphat Disord.2020 Jun;S2213-333X(20)30347-4. doi: 10.1016/j.jvsv.2020.05.019.Epub 2020-06-26.

心筋細胞外容量フラクションが心筋置換線維症を超えた予後情報を追加する

Myocardial Extracellular Volume Fraction Adds Prognostic Information Beyond Myocardial Replacement Fibrosis.
  • Eric Y Yang
  • Mohamad G Ghosn
  • Mohammad A Khan
  • Nickalaus L Gramze
  • Gerd Brunner
  • Faisal Nabi
  • Vijay Nambi
  • Sherif F Nagueh
  • Duc T Nguyen
  • Edward A Graviss
  • Erik B Schelbert
  • Christie M Ballantyne
  • William A Zoghbi
  • Dipan J Shah
  • Circ Cardiovasc Imaging.2019 12;12(12):e009535. doi: 10.1161/CIRCIMAGING.119.009535.Epub 2019-12-16.

グリア細胞由来神経栄養因子が腸管神経新生を誘導し、ヒルシュプルング病モデルマウスにおける大腸の構造と機能を改善する

Glial Cell Derived Neurotrophic Factor Induces Enteric Neurogenesis and Improves Colon Structure and Function in Mouse Models of Hirschsprung Disease.
  • Rodolphe Soret
  • Sabine Schneider
  • Guillaume Bernas
  • Briana Christophers
  • Ouliana Souchkova
  • Baptiste Charrier
  • Franziska Righini-Grunder
  • Ann Aspirot
  • Mathieu Landry
  • Steven W Kembel
  • Christophe Faure
  • Robert O Heuckeroth
  • Nicolas Pilon
  • Gastroenterology.2020 Jul;S0016-5085(20)34944-1. doi: 10.1053/j.gastro.2020.07.018.Epub 2020-07-17.

硫酸銅と亜セレン酸ナトリウムの脂質マイクロカプセル化は、デュアルフロー連続培養システムでの鼻腔微生物発酵を修飾する

Copper sulfate and sodium selenite lipid-microencapsulation modifies ruminal microbial fermentation in a dual-flow continuous-culture system.
  • J A Arce-Cordero
  • H F Monteiro
  • A L Lelis
  • L R Lima
  • R Restelatto
  • V L N Brandao
  • H Leclerc
  • D Vyas
  • A P Faciola
  • J. Dairy Sci..2020 Jun;S0022-0302(20)30426-4. doi: 10.3168/jds.2019-17913.Epub 2020-06-03.

永久歯と原始歯の近位間う蝕の検出のための近赤外透過照明とビットウイングX線撮影による目視検査の生体内での相関性

In vivo correlation of near-infrared transillumination and visual inspection with bitewing radiography for the detection of interproximal caries in permanent and primary teeth.
  • M De Zutter
  • J D Vandenbulcke
  • J W G Van Acker
  • L C Martens
  • Eur Arch Paediatr Dent.2020 Jun;10.1007/s40368-020-00538-6. doi: 10.1007/s40368-020-00538-6.Epub 2020-06-09.

小児・青年の急性骨髄性白血病に対する医薬品開発のための小児戦略フォーラムACCELERATEは、食品医薬品局の参加を得て欧州医薬品庁と共同で実施

Paediatric Strategy Forum for medicinal product development for acute myeloid leukaemia in children and adolescents: ACCELERATE in collaboration with the European Medicines Agency with participation of the Food and Drug Administration.
  • Andrew D J Pearson
  • C Michel Zwaan
  • E Anders Kolb
  • Dominik Karres
  • Julie Guillot
  • Su Young Kim
  • Lynley Marshall
  • Sarah K Tasian
  • Malcolm Smith
  • Todd Cooper
  • Peter C Adamson
  • Elly Barry
  • Bouchra Benettaib
  • Florence Binlich
  • Anne Borgman
  • Erica Brivio
  • Renaud Capdeville
  • David Delgado
  • Douglas V Faller
  • Linda Fogelstrand
  • Paula Goodman Fraenkel
  • Henrik Hasle
  • Delphine Heenen
  • Gertjan Kaspers
  • Mark Kieran
  • Jan-Henning Klusmann
  • Giovanni Lesa
  • Franca Ligas
  • Silvia Mappa
  • Hesham Mohamed
  • Andrew Moore
  • Joan Morris
  • Kerri Nottage
  • Dirk Reinhardt
  • Nicole Scobie
  • Stephen Simko
  • Thomas Winkler
  • Koen Norga
  • Gregory Reaman
  • Gilles Vassal
  • Eur. J. Cancer.2020 Jul;136:116-129. S0959-8049(20)30242-2. doi: 10.1016/j.ejca.2020.04.038.Epub 2020-07-17.

エビmiR-965は、MCL-1-ERストレス-XBP1フィードバックループを阻害することで、ヒトメラノーマ幹様細胞のアポトーシスを誘導し、そのステムネスを阻害した

Shrimp miR-965 induced the human melanoma stem-like cell apoptosis and inhibited their stemness by disrupting the MCL-1-ER stress-XBP1 feedback loop in a cross-species manner.
  • Wenlin Wu
  • Chenxi Xu
  • Xiaobo Zhang
  • An Yu
  • Le Shu
  • Stem Cell Res Ther.2020 Jun;11(1):248. 10.1186/s13287-020-01734-3. doi: 10.1186/s13287-020-01734-3.Epub 2020-06-25.

自己免疫性溶血性貧血における小さな発作性夜間ヘモグロビン尿症のクローン。臨床的な意味合いと陽性と陰性の患者における異なるサイトカインパターン

Small Paroxysmal Nocturnal Hemoglobinuria Clones in Autoimmune Hemolytic Anemia: Clinical Implications and Different Cytokine Patterns in Positive and Negative Patients.
  • Bruno Fattizzo
  • Juri Giannotta
  • Anna Zaninoni
  • Austin Kulasekararaj
  • Lilla Cro
  • Wilma Barcellini
  • Front Immunol.2020;11:1006. doi: 10.3389/fimmu.2020.01006.Epub 2020-06-04.

骨格筋線維におけるヒスチジンに富む糖タンパク質の超微細な局在化。AMPデアミナーゼとのコロケーション

Ultrastructural Localization of Histidine-rich Glycoprotein in Skeletal Muscle Fibers: Colocalization With AMP Deaminase.
  • Letizia Mattii
  • Francesco Bianchi
  • Alessandra Falleni
  • Sabina Frascarelli
  • Matilde Masini
  • Greta Alì
  • Grazia Chiellini
  • Antonietta R M Sabbatini
  • J. Histochem. Cytochem..2020 Feb;68(2):139-148. doi: 10.1369/0022155419897573.Epub 2019-12-27.

また、daf-7関連のTGF-βリガンド（Hc-tgh-2）は、Haemonchus contortusの発生に重要な役割を果たしていることが明らかになった

A daf-7-related TGF-β ligand (Hc-tgh-2) shows important regulations on the development of Haemonchus contortus.
  • Li He
  • Hui Liu
  • Bi-Ying Zhang
  • Fang-Fang Li
  • Wen-Da Di
  • Chun-Qun Wang
  • Cai-Xian Zhou
  • Lu Liu
  • Ting-Ting Li
  • Ting Zhang
  • Rui Fang
  • Min Hu
  • Parasit Vectors.2020 Jun;13(1):326. 10.1186/s13071-020-04196-x. doi: 10.1186/s13071-020-04196-x.Epub 2020-06-26.

網膜変性症のブタのヨード酢酸モデル。視覚系の形態的機能的特徴付け

The porcine iodoacetic acid model of retinal degeneration: Morpho-functional characterization of the visual system.
  • Francesca Barone
  • Luisa Vera Muscatello
  • Domenico Ventrella
  • Alberto Elmi
  • Noemi Romagnoli
  • Luciana Mandrioli
  • Josè Fernando Maya-Vetencourt
  • Cristiano Bombardi
  • Maurizio Mete
  • Giuseppe Sarli
  • Fabio Benfenati
  • Grazia Pertile
  • Maria Laura Bacci
  • Exp. Eye Res..2020 Apr;193:107979. S0014-4835(19)30435-X. doi: 10.1016/j.exer.2020.107979.Epub 2020-02-19.

腹腔鏡下腹腔外腹膜切除術における膀胱腹膜フラップを用いた骨盤腹膜再建術。多施設前向き単群コホート研究（IDEAL Phase 2A）

Pelvic peritoneum reconstruction using the bladder peritoneum flap in laparoscopic extralevator abdominoperineal excision: A multi-center, prospective single-arm cohort study (IDEAL Phase 2A).
  • Yu Shen
  • Tinghan Yang
  • Xiangbing Deng
  • Jinliang Yang
  • Wenjian Meng
  • Ziqiang Wang
  • Medicine (Baltimore).2020 Jun;99(25):e20712. 00005792-202006190-00054. doi: 10.1097/MD.0000000000020712.

撹拌槽反応器のセミバッチ運転による小麦ワラのアルカリ酸化脱リグニン化の促進

Enhancement of alkaline-oxidative delignification of wheat straw by semi-batch operation in a stirred tank reactor.
  • Alicia Hernández-Guzmán
  • Ivette Michelle Navarro-Gutiérrez
  • Perla Araceli Meléndez-Hernández
  • Javier Ulises Hernández-Beltrán
  • Héctor Hernández-Escoto
  • Bioresour. Technol..2020 Sep;312:123589. S0960-8524(20)30861-0. doi: 10.1016/j.biortech.2020.123589.Epub 2020-05-26.

ネイティブ イオン交換質量分析法を用いた、AJICAP 第一世代技術により生成された部位特異的な抗体-薬物コンジュゲートのインタクト分析およびサブユニット分析への応用

Application of Native Ion Exchange Mass Spectrometry to Intact and Subunit Analysis of Site-Specific Antibody-Drug Conjugates Produced by AJICAP First Generation Technology.
  • Yutaka Matsuda
  • Michal Kliman
  • Brian A Mendelsohn
  • J. Am. Soc. Mass Spectrom..2020 Jul;doi: 10.1021/jasms.0c00129.Epub 2020-07-01.

酵母プリオンSup35によるオリゴマーとアミロイド線維形成のダイナミクスを高速原子間力顕微鏡で観察した

Dynamics of oligomer and amyloid fibril formation by yeast prion Sup35 observed by high-speed atomic force microscopy.
  • Hiroki Konno
  • Takahiro Watanabe-Nakayama
  • Takayuki Uchihashi
  • Momoko Okuda
  • Liwen Zhu
  • Noriyuki Kodera
  • Yousuke Kikuchi
  • Toshio Ando
  • Hideki Taguchi
  • Proc. Natl. Acad. Sci. U.S.A..2020 04;117(14):7831-7836. 1916452117. doi: 10.1073/pnas.1916452117.Epub 2020-03-25.

4-コレステン-3-1は、乳がん細胞の生存率を低下させ、脂質産生を減少させ、LXR依存性コレステロールトランスポーターを増強することにより、膜ラフト局在化EGFRの発現を変化させる

4-cholesten-3-one decreases breast cancer cell viability and alters membrane raft-localized EGFR expression by reducing lipogenesis and enhancing LXR-dependent cholesterol transporters.
  • Josiane Elia
  • Delphine Carbonnelle
  • Cédric Logé
  • Lucie Ory
  • Jean-Michel Huvelin
  • Mona Tannoury
  • Mona Diab-Assaf
  • Karina Petit
  • Hassan Nazih
  • Lipids Health Dis.2019 Sep;18(1):168. 10.1186/s12944-019-1103-7. doi: 10.1186/s12944-019-1103-7.Epub 2019-09-02.

侵略的淡水魚種であるプロイセンコイ（Carassius gibelio Bloch, 1782）の肝臓とエラにおける細胞内微量元素分布の比較

Comparison of intracellular trace element distributions in the liver and gills of the invasive freshwater fish species, Prussian carp (Carassius gibelio Bloch, 1782).
  • Zrinka Dragun
  • Nesrete Krasnići
  • Dušica Ivanković
  • Vlatka Filipović Marijić
  • Tatjana Mijošek
  • Zuzana Redžović
  • Marijana Erk
  • Sci. Total Environ..2020 Aug;730:138923. S0048-9697(20)32440-2. doi: 10.1016/j.scitotenv.2020.138923.Epub 2020-04-28.

農薬による自己中毒予防における研究の優先順位を伝えるための事前経済評価の利用。スリランカ農村部における店舗ベースのゲートキーパー養成プログラムの事例

Using ex-ante economic evaluation to inform research priorities in pesticide self-poisoning prevention: The case of a shop-based gatekeeper training programme in rural Sri Lanka.
  • Sabine Margarete Damerow
  • Manjula Weerasinghe
  • Lizell Bustamante Madsen
  • Kristian Schultz Hansen
  • Melissa Pearson
  • Michael Eddleston
  • Flemming Konradsen
  • Trop. Med. Int. Health.2020 Jul;doi: 10.1111/tmi.13470.Epub 2020-07-20.

スペインのラテンアメリカ系移民における無症候性ストロンギロジア症。A Community-Based Approach

Asymptomatic Strongyloidiasis among Latin American Migrants in Spain: A Community-Based Approach.
  • Violeta Ramos-Sesma
  • Miriam Navarro
  • Jara Llenas-García
  • Concepción Gil-Anguita
  • Diego Torrús-Tendero
  • Philip Wikman-Jorgensen
  • Concepción Amador-Prous
  • María-Paz Ventero-Martín
  • Ana-María Garijo-Sainz
  • María García-López
  • Ana-Isabel Pujades-Tárraga
  • Cristina Bernal-Alcaraz
  • Antonio Santonja
  • Pedro Guevara-Hernández
  • María Flores-Chávez
  • José-María Saugar
  • José-Manuel Ramos-Rincón
  • Corazones Sin Chagas Platform
  • Pathogens.2020 Jun;9(6). E511. doi: 10.3390/pathogens9060511.Epub 2020-06-24.

マトリックスアシストレーザー脱離イオン化法およびタイムフライト質量分析法によるブラジル分離株の病原性および非病原性レプトスピラ種の同定

Identification of pathogenic and nonpathogenic Leptospira species of Brazilian isolates by Matrix Assisted Laser Desorption/Ionization and Time Flight mass spectrometry.
  • Daniel Karcher
  • Rafaella C Grenfell
  • Andrea Micke Moreno
  • Luisa Zanolli Moreno
  • Silvio Arruda Vasconcellos
  • Marcos B Heinemann
  • Joao N de Almeida Junior
  • Luiz Juliano
  • Maria A Juliano
  • Braz. J. Microbiol..2018 Oct - Dec;49(4):900-908. S1517-8382(16)31200-X. doi: 10.1016/j.bjm.2018.03.005.Epub 2018-04-13.

レーザースペックルイメージングによる術中組織灌流測定。フリーフラップ乳房再建術における術後合併症の軽減に役立つ可能性がある

Intraoperative Tissue Perfusion Measurement by Laser Speckle Imaging: A Potential Aid for Reducing Postoperative Complications in Free Flap Breast Reconstruction.
  • Cynthia To
  • Jacqueline E Rees-Lee
  • Rodney J Gush
  • Kim M Gooding
  • Nicholas H Cawrse
  • Angela C Shore
  • Andrew D H Wilson
  • Plast. Reconstr. Surg..2019 02;143(2):287e-292e. 00006534-201902000-00010. doi: 10.1097/PRS.0000000000005223.

北部ベーリング・チュクチ海沿岸の堆積物中に含まれる天然および人為的なPAHの分離。温暖化する北極圏における輸送過程への示唆

Isolating different natural and anthropogenic PAHs in the sediments from the northern Bering-Chukchi margin: Implications for transport processes in a warming Arctic.
  • Yan Lin
  • Lin Liu
  • Minggang Cai
  • Lisa A Rodenburg
  • Mahdi Chitsaz
  • Yanguang Liu
  • Mian Chen
  • Hengxiang Deng
  • Hongwei Ke
  • Sci. Total Environ..2020 Sep;736:139608. S0048-9697(20)33128-4. doi: 10.1016/j.scitotenv.2020.139608.Epub 2020-05-23.

アルコキシ-1,3,5-トリアザペンタジエン(e/ato)銅(II)錯体：テンプレートの形成とピリミジンの調製のための応用、およびアルコールのカルボニル生成物への酸化のための触媒として

Alkoxy-1,3,5-triazapentadien(e/ato) copper(II) complexes: template formation and applications for the preparation of pyrimidines and as catalysts for oxidation of alcohols to carbonyl products.
  • Maximilian N Kopylovich
  • Yauhen Yu Karabach
  • M Fátima C Guedes da Silva
  • Paweł J Figiel
  • Jamal Lasri
  • Armando J L Pombeiro
  • Chemistry.2012 Jan;18(3):899-914. doi: 10.1002/chem.201101688.Epub 2011-12-14.

ヨーロッパウナギ（Anguilla anguilla）とナイルティラピア（Oreochromis niloticus）におけるミオイノシトールリン酸合成酵素の発現：海水順化の影響

Myo-inositol phosphate synthase expression in the European eel (Anguilla anguilla) and Nile tilapia (Oreochromis niloticus): effect of seawater acclimation.
  • Svetlana Kalujnaia
  • Neil Hazon
  • Gordon Cramb
  • Am. J. Physiol. Regul. Integr. Comp. Physiol..2016 08;311(2):R287-98. ajpregu.00056.2016. doi: 10.1152/ajpregu.00056.2016.Epub 2016-06-01.

新規ホモ接合型 KCNQ3 機能喪失変異体は、非症候性知的障害と新生児期に発症する薬物依存性てんかんの原因となる

A novel homozygous KCNQ3 loss-of-function variant causes non-syndromic intellectual disability and neonatal-onset pharmacodependent epilepsy.
  • Anna Lauritano
  • Sebastien Moutton
  • Elena Longobardi
  • Frédéric Tran Mau-Them
  • Giusy Laudati
  • Piera Nappi
  • Maria Virginia Soldovieri
  • Paolo Ambrosino
  • Mauro Cataldi
  • Thibaud Jouan
  • Daphné Lehalle
  • Hélène Maurey
  • Christophe Philippe
  • Francesco Miceli
  • Antonio Vitobello
  • Maurizio Taglialatela
  • Epilepsia Open.2019 Sep;4(3):464-475. EPI412353. doi: 10.1002/epi4.12353.Epub 2019-08-11.

乾燥血液斑からの5つの原発性免疫不全症の診断とスクリーニングのための多重化プロテオミクス分析

Multiplexed Proteomic Analysis for Diagnosis and Screening of Five Primary Immunodeficiency Disorders From Dried Blood Spots.
  • Christopher J Collins
  • Fan Yi
  • Remwilyn Dayuha
  • Jeffrey R Whiteaker
  • Hans D Ochs
  • Alexandra Freeman
  • Helen C Su
  • Amanda G Paulovich
  • Gesmar R S Segundo
  • Troy Torgerson
  • Si Houn Hahn
  • Front Immunol.2020;11:464. doi: 10.3389/fimmu.2020.00464.Epub 2020-04-01.

Asplenium ruprechtii Sa.Kurata由来の新規シクロアルタン配糖体5種の構造決定とin vitro腫瘍細胞毒性評価倉田

Structural determination and in vitro tumor cytotoxicity evaluation of five new cycloartane glycosides from Asplenium ruprechtii Sa. Kurata.
  • Fang Wang
  • Zhi-Bo Jiang
  • Xiu-Li Wu
  • Da-Lian Liang
  • Ning Zhang
  • Min Li
  • Lei Shi
  • Chong-Gang Duan
  • Xiao-Li Ma
  • Dai-Zhou Zhang
  • Bioorg. Chem..2020 Jul;102:104085. S0045-2068(20)31382-1. doi: 10.1016/j.bioorg.2020.104085.Epub 2020-07-10.

白質アストロサイトでのコレステロール生合成を阻害すると、灰白質アストロサイトではなく、白質アストロサイトでのコレステロール生合成が阻害され、in vitroでの骨髄化が促進される

Impairing committed cholesterol biosynthesis in white matter astrocytes, but not grey matter astrocytes, enhances in vitro myelination.
  • Inge L Werkman
  • Janine Kövilein
  • Jenny C de Jonge
  • Wia Baron
  • J. Neurochem..2020 Jun;doi: 10.1111/jnc.15113.Epub 2020-06-30.

海馬機能とV型プロトンATPaseサブユニットB2とヒートショック認知タンパク質70とのその可能性のある関連性にピリドキシン欠乏の効果

Effects of Pyridoxine Deficiency on Hippocampal Function and Its Possible Association with V-Type Proton ATPase Subunit B2 and Heat Shock Cognate Protein 70.
  • Hyo Young Jung
  • Woosuk Kim
  • Kyu Ri Hahn
  • Hyun Jung Kwon
  • Sung Min Nam
  • Jin Young Chung
  • Yeo Sung Yoon
  • Dae Won Kim
  • Dae Young Yoo
  • In Koo Hwang
  • Cells.2020 Apr;9(5). E1067. doi: 10.3390/cells9051067.Epub 2020-04-25.

COVID-19を有する多発性骨髄腫患者の3次センターでの経験：得られた教訓と今後の道筋

A tertiary center experience of multiple myeloma patients with COVID-19: lessons learned and the path forward.
  • Bo Wang
  • Oliver Van Oekelen
  • Tarek H Mouhieddine
  • Diane Marie Del Valle
  • Joshua Richter
  • Hearn Jay Cho
  • Shambavi Richard
  • Ajai Chari
  • Sacha Gnjatic
  • Miriam Merad
  • Sundar Jagannath
  • Samir Parekh
  • Deepu Madduri
  • J Hematol Oncol.2020 07;13(1):94. 10.1186/s13045-020-00934-x. doi: 10.1186/s13045-020-00934-x.Epub 2020-07-14.

MicroRNA-30e-5pは、ウイルス感染と全身性エリテマトーデスの間の自然免疫応答の制御に統合的な役割を持っています

MicroRNA-30e-5p has an Integrated Role in the Regulation of the Innate Immune Response during Virus Infection and Systemic Lupus Erythematosus.
  • Richa Mishra
  • Sanjana Bhattacharya
  • Bhupendra Singh Rawat
  • Ashish Kumar
  • Akhilesh Kumar
  • Kavita Niraj
  • Ajit Chande
  • Puneet Gandhi
  • Dheeraj Khetan
  • Amita Aggarwal
  • Seiichi Sato
  • Prafullakumar Tailor
  • Akinori Takaoka
  • Himanshu Kumar
  • iScience.2020 Jul;23(7):101322. S2589-0042(20)30509-5. doi: 10.1016/j.isci.2020.101322.Epub 2020-07-01.

CKDはHDLのカルボニル化を増加させ、抗凝集能の低下と関連している

CKD Increases Carbonylation of HDL and Is Associated with Impaired Antiaggregant Properties.
  • Nans Florens
  • Catherine Calzada
  • Sandrine Lemoine
  • Marie Michèle Boulet
  • Nicolas Guillot
  • Christophe Barba
  • Julie Roux
  • Fréderic Delolme
  • Adeline Page
  • Jean Michel Poux
  • Maurice Laville
  • Philippe Moulin
  • Laurent Soulère
  • Fitsum Guebre-Egziabher
  • Laurent Juillard
  • Christophe O Soulage
  • J. Am. Soc. Nephrol..2020 Jul;31(7):1462-1477. ASN.2019111205. doi: 10.1681/ASN.2019111205.Epub 2020-06-09.

マダガスカルの10地区における人工妊娠中絶の頻度、危険因子、合併症：家計横断調査の結果

Frequency, risk factors, and complications of induced abortion in ten districts of Madagascar: results from a cross-sectional household survey.
  • Rila Ratovoson
  • Amber Kunkel
  • Jean Pierre Rakotovao
  • Dolores Pourette
  • Chiarella Mattern
  • Jocelyne Andriamiadana
  • Aina Harimanana
  • Patrice Piola
  • BMC Womens Health.2020 May;20(1):96. 10.1186/s12905-020-00962-2. doi: 10.1186/s12905-020-00962-2.Epub 2020-05-06.

ナイジェリア・ニジェールデルタ地域アラオジ・アバ及びエレカヒア・ポート・ハーコートにおける自動車機械工場の活動が及ぼす地球環境影響の評価

Assessment of the geo-environmental effects of activities of auto-mechanic workships at Alaoji Aba and Elekahia Port Harcourt, Niger Delta, Nigeria.
  • Nkanu Ernest Muze
  • Alexander Iheanyichukwu Opara
  • Francis Chizoruo Ibe
  • Okereke Chinwendu Njoku
  • Environ Anal Health Toxicol.2020 Jun;35(2):2020005-0. eaht.2020005. doi: 10.5620/eaht.2020005.Epub 2020-06-17.

Lactobacillus spp.は、ブロイラーの腸や肝臓でデオキシニバレノールによって誘発される形態学的変化や酸化ストレスを軽減します

Lactobacillus spp. Reduces morphological changes and oxidative stress induced by deoxynivalenol on the intestine and liver of broilers.
  • Marielen de Souza
  • Ana Angelita S Baptista
  • Milton J J Valdiviezo
  • Larissa Justino
  • Maísa F Menck-Costa
  • Camila R Ferraz
  • Eduardo M da Gloria
  • Waldiceu A Verri
  • Ana Paula F R L Bracarense
  • Toxicon.2020 Jul;S0041-0101(20)30306-8. doi: 10.1016/j.toxicon.2020.07.002.Epub 2020-07-17.

PAICSは、ヒストン脱アセチラーゼ1/2との相互作用により、胃癌の発癌に寄与し、DNA損傷応答に関与していることが明らかになった

PAICS contributes to gastric carcinogenesis and participates in DNA damage response by interacting with histone deacetylase 1/2.
  • Nan Huang
  • Chang Xu
  • Liang Deng
  • Xue Li
  • Zhixuan Bian
  • Yue Zhang
  • Shuping Long
  • Yan Chen
  • Ni Zhen
  • Guohui Li
  • Fenyong Sun
  • Cell Death Dis.2020 Jul;11(7):507. 10.1038/s41419-020-2708-5. doi: 10.1038/s41419-020-2708-5.Epub 2020-07-06.

卵巣刺激中の卵胞期後期プロゲステロン上昇は、融解サイクルにおける染色体スクリーニング済み胚の着床低下とは関連していません

Late follicular phase progesterone elevation during ovarian stimulation is not associated with decreased implantation of chromosomally screened embryos in thaw cycles.
  • Carlos Hernandez-Nieto
  • Joseph A Lee
  • Tamar Alkon-Meadows
  • Martha Luna-Rojas
  • Tanmoy Mukherjee
  • Alan B Copperman
  • Benjamin Sandler
  • Hum. Reprod..2020 Jul;deaa123. doi: 10.1093/humrep/deaa123.Epub 2020-07-10.

洗浄可能なベッドバリアと抗生物質スチュワードシップの使用は、急性期病院での病院発症感染を減少させる。レトロスペクティブなポスト前のケーススタディ

Use of a Launderable Bed Barrier and Antibiotic Stewardship to Decrease Hospital Onset Infections in an Acute Care Hospital: A Retrospective Pre-Post Case Study.
  • Edmond A Hooker
  • Peter J Mallow
  • Christine McKinney
  • Martin L Gnoni
  • Francisco Fernandez Gonzales
  • J Health Econ Outcomes Res.2019;6(3):196-202. jheor-6-3-001c.11149. doi: 10.36469/001c.11149.Epub 2019-12-12.

酸化コバルトナノ粒子とアルブミン、白血病がん細胞、病原性細菌との相互作用を、マルチスペクトロスコピック、ドッキング、細胞、抗菌の各手法を用いて探索する

Exploring the Interaction of Cobalt Oxide Nanoparticles with Albumin, Leukemia Cancer Cells and Pathogenic Bacteria by Multispectroscopic, Docking, Cellular and Antibacterial Approaches.
  • Niloofar Arsalan
  • Elahe Hassan Kashi
  • Anwarul Hasan
  • Mona Edalat Doost
  • Behnam Rasti
  • Bilal Ahamad Paray
  • Mona Zahed Nakhjiri
  • Soyar Sari
  • Majid Sharifi
  • Koorosh Shahpasand
  • Keivan Akhtari
  • Setareh Haghighat
  • Mojtaba Falahati
  • Int J Nanomedicine.2020;15:4607-4623. 257711. doi: 10.2147/IJN.S257711.Epub 2020-06-25.

ポビドンヨードは、COVID-19病の原因ウイルスであるSARS-CoV-2に対する迅速なin vitroウイルス活性を示す

Povidone-Iodine Demonstrates Rapid In Vitro Virucidal Activity Against SARS-CoV-2, The Virus Causing COVID-19 Disease.
  • Danielle E Anderson
  • Velraj Sivalingam
  • Adrian Eng Zheng Kang
  • Abhishek Ananthanarayanan
  • Harsha Arumugam
  • Timothy M Jenkins
  • Yacine Hadjiat
  • Maren Eggers
  • Infect Dis Ther.2020 Jul;10.1007/s40121-020-00316-3. doi: 10.1007/s40121-020-00316-3.Epub 2020-07-08.

タイにおける国境を越えた移民の公的健康保険制度へのアクセス問題をシステム思考で理解する

Understanding the Problem of Access to Public Health Insurance Schemes among Cross-Border Migrants in Thailand through Systems Thinking.
  • Watinee Kunpeuk
  • Pard Teekasap
  • Hathairat Kosiyaporn
  • Sataporn Julchoo
  • Mathudara Phaiyarom
  • Pigunkaew Sinam
  • Nareerut Pudpong
  • Rapeepong Suphanchaimat
  • Int J Environ Res Public Health.2020 Jul;17(14). E5113. doi: 10.3390/ijerph17145113.Epub 2020-07-15.

水の再利用を目的としたUV/HOによる新興懸念汚染物質の分解。キネティクス、メカニズム、細胞毒性解析

Degradation of contaminants of emerging concern by UV/HO for water reuse: Kinetics, mechanisms, and cytotoxicity analysis.
  • Ying Huang
  • Minghao Kong
  • Scott Coffin
  • Kristin H Cochran
  • Danielle C Westerman
  • Daniel Schlenk
  • Susan D Richardson
  • Lecheng Lei
  • Dionysios D Dionysiou
  • Water Res..2020 May;174:115587. S0043-1354(20)30123-8. doi: 10.1016/j.watres.2020.115587.Epub 2020-02-04.

ANMCOポジションペーパー。緊急の電気生理学的処置を必要とするCOVID-19が疑われる患者または確認された患者の管理のためのガイダンス

[ANMCO Position paper: Guidance for the management of suspected or confirmed COVID-19 patients requiring urgent electrophysiological procedures].
  • Michele Massimo Gulizia
  • Massimo Zecchin
  • Furio Colivicchi
  • Giuseppina Maura Francese
  • Adriano Murrone
  • Pasquale Caldarola
  • Andrea Di Lenarda
  • Serafina Valente
  • Loris Roncon
  • Enzo Amodeo
  • Nadia Aspromonte
  • Manlio Gianni Cipriani
  • Stefano Domenicucci
  • Massimo Imazio
  • Fortunato Scotto Di Uccio
  • Stefano Urbinati
  • Domenico Gabrielli
  • G Ital Cardiol (Rome).2020 05;21(5):336-340. doi: 10.1714/3343.33130.

ジペプチジルペプチダーゼ-4酵素阻害薬であるリナグリプチンは、シスプラチン誘発性神経行動障害におけるCHOPおよびGRP78バイオマーカーレベルを低下させる。可能性のある修復ゲートウェイ

Linagliptin, the dipeptidyl peptidase-4 enzyme inhibitor, lessens CHOP and GRP78 biomarkers levels in cisplatin-induced neurobehavioral deficits: A possible restorative gateway.
  • Omnia S El-Deeb
  • Gehan M Soliman
  • Rasha O Elesawy
  • J. Biochem. Mol. Toxicol..2020 Jun;:e22541. doi: 10.1002/jbt.22541.Epub 2020-06-22.

固有の淡水性海綿体Ochridaspongia rotunda (Arndt, 1937)からのキチンの同定とその構造に関する初めての知見

Identification and first insights into the structure of chitin from the endemic freshwater demosponge Ochridaspongia rotunda (Arndt, 1937).
  • Trajce Talevski
  • Aleksandra Talevska Leshoska
  • Elena Pejoski
  • Boris Pejin
  • Tomasz Machałowski
  • Marcin Wysokowski
  • Mikhail V Tsurkan
  • Olga Petrova
  • Viktor Sivkov
  • Rajko Martinovic
  • Snezana Pantovic
  • Yuliya Khrunyk
  • Volodymyr Trylis
  • Andriy Fursov
  • Mirko Djurovic
  • Teofil Jesionowski
  • Hermann Ehrlich
  • Int. J. Biol. Macromol..2020 Jun;S0141-8130(20)33702-8. doi: 10.1016/j.ijbiomac.2020.06.247.Epub 2020-06-29.

血液学的悪性腫瘍患者に対する非骨髄芽腫性条件付けによる同種造血細胞移植。20年以上にわたる治療成績の改善

Allogeneic hematopoietic cell transplantation with non-myeloablative conditioning for patients with hematologic malignancies: Improved outcomes over two decades.
  • Jason P Cooper
  • Barry E Storer
  • Noa Granot
  • Boglark Gyurkocza
  • Mohamed L Sorror
  • Thomas R Chauncey
  • Judith Shizuru
  • Georg-Nikolaus Franke
  • Michael B Maris
  • Michael Boyer
  • Benedetto Bruno
  • Firoozeh Sahebi
  • Amelia A Langston
  • Parameswaran Hari
  • Edward D Agura
  • Søren Lykke Petersen
  • Richard T Maziarz
  • Wolfgang Bethge
  • Julie Asch
  • Jonathan A Gutman
  • Gitte Olesen
  • Andrew M Yeager
  • Kai Hübel
  • William J Hogan
  • David G Maloney
  • Marco Mielcarek
  • Paul J Martin
  • Mary E D Flowers
  • George E Georges
  • Ann E Woolfrey
  • H Joachim Deeg
  • Bart L Scott
  • George B McDonald
  • Rainer Storb
  • Brenda M Sandmaier
  • Haematologica.2020 Jun;haematol.2020.248187. doi: 10.3324/haematol.2020.248187.Epub 2020-06-04.

再発・難治性急性骨髄性白血病患者を対象としたselinexorとcytarabineおよびidarubicinの第Ⅱ相試験

A Phase II study of selinexor plus cytarabine and idarubicin in patients with relapsed/refractory acute myeloid leukaemia.
  • Walter Fiedler
  • Joerg Chromik
  • Stefanie Amberg
  • Maxim Kebenko
  • Felicitas Thol
  • Vera Schlipfenbacher
  • Anne Christine Wilke
  • Franziska Modemann
  • Melanie Janning
  • Hubert Serve
  • Arnold Ganser
  • Carsten Bokemeyer
  • Susann Theile
  • Ute Deppermann
  • Anne L Kranich
  • Michael Heuser
  • Br. J. Haematol..2020 Jun;doi: 10.1111/bjh.16804.Epub 2020-06-09.

月経周期に関連した抑うつ症状、生理的身体症状、乳房症状、不安症状における免疫系および酸化経路の役割。性ホルモンによる調節

The role of immune and oxidative pathways in menstrual cycle associated depressive, physio-somatic, breast and anxiety symptoms: Modulation by sex hormones.
  • Chutima Roomruangwong
  • Andressa Keiko Matsumoto
  • Ana Paula Michelin
  • Laura de Oliveira Semeão
  • João Victor de Lima Pedrão
  • Estefania G Moreira
  • Sunee Sirivichayakul
  • Andre Carvalho
  • Decio S Barbosa
  • Michael Maes
  • J Psychosom Res.2020 Aug;135:110158. S0022-3999(20)30169-0. doi: 10.1016/j.jpsychores.2020.110158.Epub 2020-05-23.

SIRT1/2の阻害は、ヒト肺癌細胞において、ATF4-DDIT4-mTORC1軸を介して、HSPA5アセチル化をアップレギュレーションし、生存率の高いオートファジーを誘導する

Inhibition of SIRT1/2 upregulates HSPA5 acetylation and induces pro-survival autophagy via ATF4-DDIT4-mTORC1 axis in human lung cancer cells.
  • Ning Mu
  • Yuanjiu Lei
  • Yu Wang
  • Yingying Wang
  • Qinghui Duan
  • Guilin Ma
  • Xiangguo Liu
  • Ling Su
  • Apoptosis.2019 10;24(9-10):798-811. 10.1007/s10495-019-01559-3. doi: 10.1007/s10495-019-01559-3.

レバノン女性における抗ミューラーホルモン値の年齢依存的変化：基礎FSHおよびLH値、LH/FSH比との相関：横断的研究

Age-dependent changes in anti-Müllerian hormone levels in Lebanese females: correlation with basal FSH and LH levels and LH/FSH ratio: a cross-sectional study.
  • Eddie Racoubian
  • Gulzhanat Aimagambetova
  • Ramzi R Finan
  • Wassim Y Almawi
  • BMC Womens Health.2020 Jun;20(1):134. 10.1186/s12905-020-00998-4. doi: 10.1186/s12905-020-00998-4.Epub 2020-06-26.

フリードライヒ失調症の創薬に向けての進展ヒトフラタキシン蛋白質の発現をより強力に活性化する合成オリゴヌクレオチドの同定

Progress towards drug discovery for Friedreich's Ataxia: Identifying synthetic oligonucleotides that more potently activate expression of human frataxin protein.
  • Xiulong Shen
  • Johnathan Wong
  • Thahza P Prakash
  • Frank Rigo
  • Yanjie Li
  • Marek Napierala
  • David R Corey
  • Bioorg. Med. Chem..2020 Jun;28(11):115472. S0968-0896(20)30286-8. doi: 10.1016/j.bmc.2020.115472.Epub 2020-04-05.

高性能リチウムイオン電池のための模擬電解スラッジ浸出液からの遷移金属リサイクルによるヘテロ構造NiFeO-Cナノロッドの構築

Construction of heterostructured NiFeO-C nanorods by transition metal recycling from simulated electroplating sludge leaching solution for high performance lithium ion batteries.
  • Xueqian Lei
  • Youpeng Li
  • Changzhou Weng
  • Yanzhen Liu
  • Weizhen Liu
  • Junhua Hu
  • Chenghao Yang
  • Zhang Lin
  • Meilin Liu
  • Nanoscale.2020 Jul;12(25):13398-13406. doi: 10.1039/d0nr02290j.