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日本語AIでPubMedを検索

日本語AIでPubMedを検索

PubMedの提供する医学論文データベースを日本語で検索できます。AI(Deep Learning)を活用した機械翻訳エンジンにより、精度高く日本語へ翻訳された論文をご参照いただけます。

2020年07月 みんなが読んでいる論文

シリカコートプラスチックチューブを用いて作製した濃縮成長因子マトリックスは、ガラスチューブを用いて作製したものと血小板の分布に違いがあることを明らかにした。新規な近赤外イメージングに基づく定量的手法の応用

Concentrated Growth Factor Matrices Prepared Using Silica-Coated Plastic Tubes Are Distinguishable From Those Prepared Using Glass Tubes in Platelet Distribution: Application of a Novel Near-Infrared Imaging-Based, Quantitative Technique.
  • Sadahiro Yamaguchi
  • Hachidai Aizawa
  • Atsushi Sato
  • Tetsuhiro Tsujino
  • Kazushige Isobe
  • Yutaka Kitamura
  • Taisuke Watanabe
  • Hajime Okudera
  • Carlos Fernando Mourão
  • Tomoyuki Kawase
  • Front Bioeng Biotechnol.2020;8:600. doi: 10.3389/fbioe.2020.00600.Epub 2020-06-16.

COVID-19患者からの致死量の近いSARS-CoV-2中和抗体の縦断的分離

Longitudinal Isolation of Potent Near-Germline SARS-CoV-2-Neutralizing Antibodies from COVID-19 Patients.
  • Christoph Kreer
  • Matthias Zehner
  • Timm Weber
  • Meryem S Ercanoglu
  • Lutz Gieselmann
  • Cornelius Rohde
  • Sandro Halwe
  • Michael Korenkov
  • Philipp Schommers
  • Kanika Vanshylla
  • Veronica Di Cristanziano
  • Hanna Janicki
  • Reinhild Brinker
  • Artem Ashurov
  • Verena Krähling
  • Alexandra Kupke
  • Hadas Cohen-Dvashi
  • Manuel Koch
  • Jan Mathis Eckert
  • Simone Lederer
  • Nico Pfeifer
  • Timo Wolf
  • Maria J G T Vehreschild
  • Clemens Wendtner
  • Ron Diskin
  • Henning Gruell
  • Stephan Becker
  • Florian Klein
  • Cell.2020 08;182(4):843-854.e12. S0092-8674(20)30821-7. doi: 10.1016/j.cell.2020.06.044.Epub 2020-07-13.

グラスアイオノマーセメントとコンポジットレジンを比較した非カリウス性頸部病変の修復。システマティックレビューとメタアナリシス

Glass ionomer cements compared with composite resin in restoration of noncarious cervical lesions: A systematic review and meta-analysis.
  • Isis Morais Bezerra
  • Arella Cristina Muniz Brito
  • Simone Alves de Sousa
  • Bianca Marques Santiago
  • Yuri Wanderley Cavalcanti
  • Leopoldina de Fátima Dantas de Almeida
  • Heliyon.2020 May;6(5):e03969. S2405-8440(20)30814-8. doi: 10.1016/j.heliyon.2020.e03969.Epub 2020-05-21.

歯周病患者における審美的インプラントリハビリテーション。外科的・補綴的根拠

Aesthetic Implant Rehabilitation in Periodontally Compromised Patients: A Surgical and Prosthetic Rationale.
  • Erica Dorigatti De Avila
  • Rafael Scaf de Molon
  • Mauricio de Almeida Cardoso
  • Leopoldino Capelozza-Filho
  • Luiz Antonio Borelli Barros-Filho
  • Takahiro Ogawa
  • Francisco de Assis Mollo
  • Luiz Antonio Borelli de Barros
  • J Int Acad Periodontol.2016 Oct;18:120-128. 18-4-2016-120. Epub 2016-10-07.

化学療法を受けたラットの歯周炎の治療におけるスケーリングと根のプレーニングに関連したラクトバチルス・ロイテリ

Lactobacillus reuteri associated with scaling and root planing in the treatment of periodontitis in rats submitted to chemotherapy.
  • Daniela Maria Janjácomo Miessi
  • Valdir Gouveia Garcia
  • Edilson Ervolino
  • Vitor Scalet
  • Marta Aparecida Alberton Nuernberg
  • Otavio Marino Dos Santos Neto
  • Tiago Esgalha da Rocha
  • Leticia Helena Theodoro
  • Arch. Oral Biol..2020 Sep;117:104825. S0003-9969(20)30203-X. doi: 10.1016/j.archoralbio.2020.104825.Epub 2020-06-24.

咽頭嚥下障害のリスクがある患者における嚥下スクリーニングのための非侵襲的装置の開発:プロスペクティブな探索的研究の結果

Development of a Non-invasive Device for Swallow Screening in Patients at Risk of Oropharyngeal Dysphagia: Results from a Prospective Exploratory Study.
  • Catriona M Steele
  • Rajat Mukherjee
  • Juha M Kortelainen
  • Harri Pölönen
  • Michael Jedwab
  • Susan L Brady
  • Kayla Brinkman Theimer
  • Susan Langmore
  • Luis F Riquelme
  • Nancy B Swigert
  • Philip M Bath
  • Larry B Goldstein
  • Richard L Hughes
  • Dana Leifer
  • Kennedy R Lees
  • Atte Meretoja
  • Natalia Muehlemann
  • Dysphagia.2019 10;34(5):698-707. 10.1007/s00455-018-09974-5. doi: 10.1007/s00455-018-09974-5.Epub 2019-01-05.

呼吸調節とヨギックエクササイズ COVID-19パンデミックを管理する最前線の病院や長期ケアホームのスタッフのための穏やかさと幸福のためのオンラインセラピー(BREATH)。無作為化比較試験のためのフィージビリティスタディのための研究プロトコルの構造化された要約

Breath Regulation and yogic Exercise An online Therapy for calm and Happiness (BREATH) for frontline hospital and long-term care home staff managing the COVID-19 pandemic: A structured summary of a study protocol for a feasibility study for a randomised controlled trial.
  • Ka Sing Paris Lai
  • Christine Watt
  • Emily Ionson
  • Imants Baruss
  • Cheryl Forchuk
  • Javeed Sukhera
  • Amer M Burhan
  • Akshya Vasudev
  • Trials.2020 Jul;21(1):648. 10.1186/s13063-020-04583-w. doi: 10.1186/s13063-020-04583-w.Epub 2020-07-14.

MAPK活性化を介したソニックヘッジホッグシグナル伝達の阻害は、化学療法誘発性脱毛症を制御する

Inhibition of sonic hedgehog signaling via MAPK activation controls chemotherapy-induced alopecia.
  • Iain S Haslam
  • GuiXuan Zhou
  • GuoJiang Xie
  • Xu Teng
  • XiuLan Ao
  • ZhiPeng Yan
  • Eleanor Smart
  • David Rutkowski
  • Justyna Wierzbicka
  • YongJian Zhou
  • Zhen Huang
  • YanDing Zhang
  • Nilofer Farjo
  • Bessam Farjo
  • Ralf Paus
  • ZhiCao Yue
  • J. Invest. Dermatol..2020 Jul;S0022-202X(20)31831-5. doi: 10.1016/j.jid.2020.05.118.Epub 2020-07-16.

歯間ブラシとシリコンコーティングされた歯間ピックの臨床的有効性と患者の受容性の比較:無作為化分割口内前向き臨床試験

Comparison of clinical efficacy and patient acceptance of interdental brush and silicone coated interdental pick: a randomized split-mouth, prospective clinical trial.
  • Gülbahar Ustaoğlu
  • Esra Ercan
  • Kerem Çağlar Gümüş
  • Clin Oral Investig.2020 Jun;24(6):2121-2127. 10.1007/s00784-020-03293-6. doi: 10.1007/s00784-020-03293-6.Epub 2020-05-19.

移動式キャビン病院におけるCOVID-19を有する軽度中等度患者の臨床的特徴と予後因子。A Retrospective, Single-Center Study

The Clinical Characteristics and Prognosis Factors of Mild-Moderate Patients With COVID-19 in a Mobile Cabin Hospital: A Retrospective, Single-Center Study.
  • Jishou Zhang
  • Menglong Wang
  • Mengmeng Zhao
  • Shanshan Guo
  • Yao Xu
  • Jing Ye
  • Wen Ding
  • Zhen Wang
  • Di Ye
  • Wei Pan
  • Menglin Liu
  • Dan Li
  • Zhen Luo
  • Jianfang Liu
  • Jun Wan
  • Front Public Health.2020;8:264. doi: 10.3389/fpubh.2020.00264.Epub 2020-06-05.

Proactive Prophylaxis With Azithromycin and HydroxyChloroquine in Hospitalised Patients With COVID-19(ProPAC-COVID)。無作為化比較試験の試験計画書の構造化された要約

Proactive Prophylaxis With Azithromycin and HydroxyChloroquine in Hospitalised Patients With COVID-19 (ProPAC-COVID): A structured summary of a study protocol for a randomised controlled trial.
  • Pradeesh Sivapalan
  • Charlotte Suppli Ulrik
  • Rasmus Dahlin Bojesen
  • Therese Sophie Lapperre
  • Josefin Viktoria Eklöf
  • Kjell Erik Julius Håkansson
  • Andrea Browatzki
  • Casper Tidemansen
  • Jon Torgny Wilcke
  • Julie Janner
  • Vibeke Gottlieb
  • Howraman Meteran
  • Celeste Porsbjerg
  • Birgitte Lindegaard Madsen
  • Mia Moberg
  • Lars Pedersen
  • Thomas Lars Benfield
  • Jens Dilling Lundgren
  • Filip Krag Knop
  • Tor Biering-Sørensen
  • Muzhda Ghanizada
  • Tine Peick Sonne
  • Uffe Christian Steinholtz Bødtger
  • Sidse Graff Jensen
  • Daniel Bech Rasmussen
  • Eva Brøndum
  • Oliver Djurhuus Tupper
  • Susanne Wiemann Sørensen
  • Gitte Alstrup
  • Christian Borbjerg Laursen
  • Ulla Weinrich Møller
  • Asger Sverrild
  • Jens-Ulrik Stæhr Jensen
  • Trials.2020 Jun;21(1):513. 10.1186/s13063-020-04409-9. doi: 10.1186/s13063-020-04409-9.Epub 2020-06-10.

妊娠前のカルシウム摂取量と妊娠初期の高血圧性障害との関連性:日本環境と子どもの研究

Association between pre-pregnancy calcium intake and hypertensive disorders during the first pregnancy: the Japan environment and children's study.
  • Hyo Kyozuka
  • Tsuyoshi Murata
  • Toma Fukuda
  • Akiko Yamaguchi
  • Aya Kanno
  • Shun Yasuda
  • Akiko Sato
  • Yuka Ogata
  • Masahito Kuse
  • Mitsuaki Hosoya
  • Seiji Yasumura
  • Koichi Hashimoto
  • Hidekazu Nishigori
  • Keiya Fujimori
  • BMC Pregnancy Childbirth.2020 Jul;20(1):424. 10.1186/s12884-020-03108-2. doi: 10.1186/s12884-020-03108-2.Epub 2020-07-28.

歯科用エアゾール中の細菌を減少させるための前処置型マウスウォッシュの有効性:無作為化臨床試験

Effectiveness of a pre-procedural mouthwash in reducing bacteria in dental aerosols: randomized clinical trial
  • Belén Retamal-Valdes
  • Geisla Mary Soares
  • Bernal Stewart
  • Luciene Cristina Figueiredo
  • Marcelo Faveri
  • Steven Miller
  • Yun Po Zhang
  • Magda Feres
  • Braz Oral Res.2017 03;31:e21. S1806-83242017000100221. doi: 10.1590/1807-3107BOR-2017.vol31.0021.Epub 2017-03-30.

COVID-19に向けた疾患発現の調査と母集団ベースの検証と薬物再利用へのネットワークメディスンアプローチ

A Network Medicine Approach to Investigation and Population-based Validation of Disease Manifestations and Drug Repurposing for COVID-19.
  • Yadi Zhou
  • Yuan Hou
  • Jiayu Shen
  • Asha Kallianpur
  • Joe Zein
  • Daniel A Culver
  • Samar Farha
  • Suzy Comhair
  • Claudio Fiocchi
  • Michaela U Gack
  • Reena Mehra
  • Thaddeus Stappenbeck
  • Timothy Chan
  • Charis Eng
  • Jae U Jung
  • Lara Jehi
  • Serpil Erzurum
  • Feixiong Cheng
  • ChemRxiv.2020 Jul;12579137. doi: 10.26434/chemrxiv.12579137.v1.Epub 2020-07-02.

前頭側頭型認知症、非定型・若年発症アルツハイマー病、遺伝性認知症におけるうつ病、不安、無気力の有病率の系統的レビュー

A systematic review of the prevalence of depression, anxiety, and apathy in frontotemporal dementia, atypical and young-onset Alzheimer's disease, and inherited dementia.
  • Jessica D Collins
  • Susie M D Henley
  • Aida Suárez-González
  • Int Psychogeriatr.2020 Jul;:1-20. S1041610220001118. doi: 10.1017/S1041610220001118.Epub 2020-07-20.

固定器具の脱着時に発生する粒子状物質。フラッシュフリーセラミックブラケットの使用の効果を評価するための実験室調査と無作為化臨床試験

Particulate production during debonding of fixed appliances: Laboratory investigation and randomized clinical trial to assess the effect of using flash-free ceramic brackets.
  • Paragh Vig
  • Nikki E Atack
  • Jonathan R Sandy
  • Martyn Sherriff
  • Anthony J Ireland
  • Am J Orthod Dentofacial Orthop.2019 Jun;155(6):767-778. S0889-5406(19)30135-0. doi: 10.1016/j.ajodo.2019.02.010.

2つの口腔内局所麻酔薬を比較するための定量的感覚閾値分析を用いた概念実証研究

A Proof-of-concept Study Using Quantitative Sensory Threshold Analysis to Compare Two Intraoral Topical Anesthetics.
  • Elliot V Hersh
  • Stacey Secreto
  • Steven Wang
  • Helen Giannakopoulos
  • Mohammad Mousavian
  • Bret Lesavoy
  • Matthew C Hutcheson
  • John T Farrar
  • Ping Wang
  • Geraldine Doyle
  • Stephen A Cooper
  • Clin Ther.2019 02;41(2):291-302. S0149-2918(18)30608-8. doi: 10.1016/j.clinthera.2018.12.009.Epub 2019-01-17.

初期の歯垢形成および歯肉炎症に対するオゾン水洗口剤の有効性:無作為化対照クロスオーバー臨床試験

Efficacy of ozonated water mouthwash on early plaque formation and gingival inflammation: a randomized controlled crossover clinical trial.
  • Alessandra Cardoso Nicolini
  • Isadora Dos Santos Rotta
  • Gerson Pedro José Langa
  • Stephanie Anagnostopoulos Friedrich
  • David Alejandro Arroyo-Bonilla
  • Marcius Comparsi Wagner
  • Patrícia Weidlich
  • Cassiano Kuchenbecker Rösing
  • Juliano Cavagni
  • Clin Oral Investig.2020 Jul;10.1007/s00784-020-03441-y. doi: 10.1007/s00784-020-03441-y.Epub 2020-07-04.

ポンペ病患者の免疫寛容誘導を目的としたリツキシマブ投与の安全性と有効性に、IVIG投与のタイミングが影響を与える可能性があることを明らかにした

The potential impact of timing of IVIG administration on safety and efficacy of rituximab administration in the setting of immune tolerance induction for patients with Pompe disease.
  • Ankit K Desai
  • Amy S Rosenberg
  • Priya S Kishnani
  • Clin. Immunol..2020 Jul;:108541. S1521-6616(20)30116-9. doi: 10.1016/j.clim.2020.108541.Epub 2020-07-15.

ポジションペーパー:歯周病学における超音波スケーラーと超音波スケーラー.アメリカ歯周病学会の研究・科学・治療委員会

Position paper: sonic and ultrasonic scalers in periodontics. Research, Science and Therapy Committee of the American Academy of Periodontology.
  • C L Drisko
  • D L Cochran
  • T Blieden
  • O J Bouwsma
  • R E Cohen
  • P Damoulis
  • J B Fine
  • G Greenstein
  • J Hinrichs
  • M J Somerman
  • V Iacono
  • R J Genco
  • J. Periodontol..2000 Nov;71(11):1792-801. doi: 10.1902/jop.2000.71.11.1792.

強化された磁気共鳴イメージングと腫瘍治療のためのオルサラジンナノ粒子のフリン媒介細胞内自己組織化

Furin-mediated intracellular self-assembly of olsalazine nanoparticles for enhanced magnetic resonance imaging and tumour therapy.
  • Yue Yuan
  • Jia Zhang
  • Xiaoliang Qi
  • Shuoguo Li
  • Guanshu Liu
  • Soumik Siddhanta
  • Ishan Barman
  • Xiaolei Song
  • Michael T McMahon
  • Jeff W M Bulte
  • Nat Mater.2019 12;18(12):1376-1383. 10.1038/s41563-019-0503-4. doi: 10.1038/s41563-019-0503-4.Epub 2019-10-21.

食餌性脂肪は、雄性マウスのグリア線維性酸性タンパク質陽性細胞とミクログリアを含む食後の視床下部の炎症を悪化させる

Dietary fat exacerbates postprandial hypothalamic inflammation involving glial fibrillary acidic protein-positive cells and microglia in male mice.
  • Céline Cansell
  • Katharina Stobbe
  • Clara Sanchez
  • Ophélia Le Thuc
  • Coralie-Anne Mosser
  • Selma Ben-Fradj
  • Joris Leredde
  • Cynthia Lebeaupin
  • Delphine Debayle
  • Lucile Fleuriot
  • Frédéric Brau
  • Nadège Devaux
  • Alexandre Benani
  • Etienne Audinat
  • Nicolas Blondeau
  • Jean-Louis Nahon
  • Carole Rovère
  • Glia.2020 Jul;doi: 10.1002/glia.23882.Epub 2020-07-13.

ハマド総合病院に入院したTIAS(一過性脳虚血発作)および脳卒中患者の健康を最適化するための前向き研究

Prospective study to optimize the health of patients with TIAS (transient ischemic attack) and stroke admitted to the Hamad General Hospital.
  • Yahia Z Imam
  • Mouhand F H Mohamed
  • Mohamed S Abdelmoneim
  • Mark Santos
  • Nima Alkhawad
  • Abdul Salam
  • Numan Amir
  • Maher Saqqur
  • Ahmad Muhammad
  • Ahmed Elsoutohy
  • Saadat Kamran
  • Naveed Akhtar
  • Abdul Salim Kiliyanni
  • Ahmed Own
  • Dirk Deleu
  • Ashfaq Shuaib
  • Medicine (Baltimore).2020 Jul;99(28):e20694. 00005792-202007100-00016. doi: 10.1097/MD.0000000000020694.

COVID-19時代の口腔外科・顎顔面外科医への配慮。患者と医療従事者の安全を守るためのソリューションを維持できるか?

Considerations for Oral and Maxillofacial Surgeons in COVID-19 Era: Can We Sustain the Solutions to Keep Our Patients and Healthcare Personnel Safe?
  • Radhika Chigurupati
  • Neeraj Panchal
  • Andrew M Henry
  • Hussam Batal
  • Amit Sethi
  • Richard D'innocenzo
  • Pushkar Mehra
  • Deepak G Krishnan
  • Steven M Roser
  • J. Oral Maxillofac. Surg..2020 May;S0278-2391(20)30551-6. doi: 10.1016/j.joms.2020.05.027.Epub 2020-05-24.

無機ウシ骨ミネラルを用いた隆起部保存の成績のレトロスペクティブ分析。移植された抜歯窩の治癒後に設置されたインプラントの限界骨レベル

Retrospective Analysis of the Outcome of Ridge Preservation with Anorganic Bovine Bone Mineral: Marginal Bone Level at Implants Placed Following Healing of Grafted Extraction Sockets.
  • Ivy H Wu
  • Neema Bakhshalian
  • Razmik Galaustian
  • Roshanak Baghai Naini
  • Seiko Min
  • Marcelo Freire
  • Homayoun H Zadeh
  • Int J Periodontics Restorative Dent.2019 Jan/Feb;39(1):131-140. doi: 10.11607/prd.3308.

食欲不振と咀嚼機能の低下がサルコペニアに及ぼす影響。3年間のコホート研究

Combined effect of poor appetite and low masticatory function on sarcopenia in community-dwelling Japanese adults aged ≥ 75 years: A 3-year cohort study.
  • Soichiro Senoo
  • Masanori Iwasaki
  • Yumi Kimura
  • Satoko Kakuta
  • Chihiro Masaki
  • Taizo Wada
  • Ryota Sakamoto
  • Yasuko Ishimoto
  • Michiko Fujisawa
  • Kiyohito Okumiya
  • Toshihiro Ansai
  • Kozo Matsubayashi
  • Ryuji Hosokawa
  • J Oral Rehabil.2020 May;47(5):643-650. doi: 10.1111/joor.12949.Epub 2020-03-08.

食欲不振と咀嚼機能の低下がサルコペニアに及ぼす影響。3年間のコホート研究

Combined effect of poor appetite and low masticatory function on sarcopenia in community-dwelling Japanese adults aged ≥ 75 years: A 3-year cohort study.
  • Soichiro Senoo
  • Masanori Iwasaki
  • Yumi Kimura
  • Satoko Kakuta
  • Chihiro Masaki
  • Taizo Wada
  • Ryota Sakamoto
  • Yasuko Ishimoto
  • Michiko Fujisawa
  • Kiyohito Okumiya
  • Toshihiro Ansai
  • Kozo Matsubayashi
  • Ryuji Hosokawa
  • J Oral Rehabil.2020 May;47(5):643-650. doi: 10.1111/joor.12949.Epub 2020-03-08.

食欲不振と咀嚼機能の低下がサルコペニアに及ぼす複合的な影響。3年間のコホート研究

Combined effect of poor appetite and low masticatory function on sarcopenia in community-dwelling Japanese adults aged ≥ 75 years: A 3-year cohort study.
  • Soichiro Senoo
  • Masanori Iwasaki
  • Yumi Kimura
  • Satoko Kakuta
  • Chihiro Masaki
  • Taizo Wada
  • Ryota Sakamoto
  • Yasuko Ishimoto
  • Michiko Fujisawa
  • Kiyohito Okumiya
  • Toshihiro Ansai
  • Kozo Matsubayashi
  • Ryuji Hosokawa
  • J Oral Rehabil.2020 May;47(5):643-650. doi: 10.1111/joor.12949.Epub 2020-03-08.

即時象牙質封鎖または遅延象牙質封鎖を用いて接着した二珪酸リチウム歯後部分修復物の3年後の機能の生存率に関する無作為化臨床試験

Randomized clinical trial on the survival of lithium disilicate posterior partial restorations bonded using immediate or delayed dentin sealing after 3 years of function.
  • C R G van den Breemer
  • M S Cune
  • M Özcan
  • L Z Naves
  • W Kerdijk
  • M M M Gresnigt
  • J Dent.2019 06;85:1-10. S0300-5712(18)30237-9. doi: 10.1016/j.jdent.2019.02.001.Epub 2019-04-09.

メタボリックシンドロームの症状の治療のための新薬候補としてのBGP-15化学薬剤の薬理学的概要

Pharmacological Overview of the BGP-15 Chemical Agent as a New Drug Candidate for the Treatment of Symptoms of Metabolic Syndrome.
  • Ágota Pető
  • Dóra Kósa
  • Pálma Fehér
  • Zoltán Ujhelyi
  • Dávid Sinka
  • Miklós Vecsernyés
  • Zoltán Szilvássy
  • Béla Juhász
  • Zoltán Csanádi
  • László Vígh
  • Ildikó Bácskay
  • Molecules.2020 Jan;25(2). E429. doi: 10.3390/molecules25020429.Epub 2020-01-20.

COVID-19の危機の間、訪問者を老人ホームに戻すことを認める。初めての経験とウェルビーイングへの影響に関するオランダの全国研究

Allowing Visitors Back in the Nursing Home During the COVID-19 Crisis: A Dutch National Study Into First Experiences and Impact on Well-Being.
  • Hilde Verbeek
  • Debby L Gerritsen
  • Ramona Backhaus
  • Bram S de Boer
  • Raymond T C M Koopmans
  • Jan P H Hamers
  • J Am Med Dir Assoc.2020 Jul;21(7):900-904. S1525-8610(20)30526-0. doi: 10.1016/j.jamda.2020.06.020.Epub 2020-06-15.

腎機能が異なる患者におけるペメトレキセドの個々の薬物動態を推定するための限定的なサンプリングスケジュール

A limited sampling schedule to estimate individual pharmacokinetics of pemetrexed in patients with varying renal functions.
  • Nikki de Rouw
  • Sabine Visser
  • Stijn L W Koolen
  • Joachim G J V Aerts
  • Michel M van den Heuvel
  • Hieronymus J Derijks
  • David M Burger
  • Rob Ter Heine
  • Cancer Chemother. Pharmacol..2020 01;85(1):231-235. 10.1007/s00280-019-04006-x. doi: 10.1007/s00280-019-04006-x.Epub 2019-12-18.

早産を予防するための妊娠者における細菌性膣症のスクリーニング。米国予防サービス・タスクフォース勧告声明

Screening for Bacterial Vaginosis in Pregnant Persons to Prevent Preterm Delivery: US Preventive Services Task Force Recommendation Statement.
  • Douglas K Owens
  • Karina W Davidson
  • Alex H Krist
  • Michael J Barry
  • Michael Cabana
  • Aaron B Caughey
  • Katrina Donahue
  • Chyke A Doubeni
  • John W Epling
  • Martha Kubik
  • Gbenga Ogedegbe
  • Lori Pbert
  • Michael Silverstein
  • Melissa A Simon
  • Chien-Wen Tseng
  • John B Wong
  • JAMA.2020 04;323(13):1286-1292. 2764189. doi: 10.1001/jama.2020.2684.

SARS-CoV-2感染と病原体のマウスモデル

A Mouse Model of SARS-CoV-2 Infection and Pathogenesis.
  • Shi-Hui Sun
  • Qi Chen
  • Hong-Jing Gu
  • Guan Yang
  • Yan-Xiao Wang
  • Xing-Yao Huang
  • Su-Su Liu
  • Na-Na Zhang
  • Xiao-Feng Li
  • Rui Xiong
  • Yan Guo
  • Yong-Qiang Deng
  • Wei-Jin Huang
  • Quan Liu
  • Quan-Ming Liu
  • Yue-Lei Shen
  • Yong Zhou
  • Xiao Yang
  • Tong-Yan Zhao
  • Chang-Fa Fan
  • Yu-Sen Zhou
  • Cheng-Feng Qin
  • You-Chun Wang
  • Cell Host Microbe.2020 07;28(1):124-133.e4. S1931-3128(20)30302-4. doi: 10.1016/j.chom.2020.05.020.Epub 2020-05-27.

癌遺伝子BCL6はDNA損傷に反応して神経膠芽腫でアップレギュレーションされ、治療後の生存を促進する

The oncogene BCL6 is up-regulated in glioblastoma in response to DNA damage, and drives survival after therapy.
  • Marie-Sophie Fabre
  • Nicole M Stanton
  • Tania L Slatter
  • Samuel Lee
  • Dinindu Senanayake
  • Rosemary M A Gordon
  • M Leticia Castro
  • Matthew R Rowe
  • Ahmad Taha
  • Janice A Royds
  • Noelyn Hung
  • Ari M Melnick
  • Melanie J McConnell
  • PLoS ONE.2020;15(4):e0231470. PONE-D-19-26346. doi: 10.1371/journal.pone.0231470.Epub 2020-04-22.

(エピ)遺伝学的プロファイリングによる、Beckwith-Wiedemann症候群の不一致を示す女性一卵性双生児の胎外組織と出生後組織の解析

(Epi)genetic profiling of extraembryonic and postnatal tissues from female monozygotic twins discordant for Beckwith-Wiedemann syndrome.
  • Laura Fontana
  • Maria F Bedeschi
  • Giulia A Cagnoli
  • Jole Costanza
  • Nicola Persico
  • Silvana Gangi
  • Matteo Porro
  • Paola F Ajmone
  • Patrizia Colapietro
  • Carlo Santaniello
  • Milena Crippa
  • Silvia M Sirchia
  • Monica Miozzo
  • Silvia Tabano
  • Mol Genet Genomic Med.2020 Jul;:e1386. doi: 10.1002/mgg3.1386.Epub 2020-07-06.

腰椎椎間体癒合の実現可能性を評価するための新しい修正Moroの分類と斜め回廊グレーディングの信頼性

Reliability of the new modified Moro's classification and oblique corridor grading to assess the feasibility of oblique lumbar interbody fusion.
  • Arun-Kumar Kaliya-Perumal
  • Julia Poh Hwee Ng
  • Tamara Lee Ting Soh
  • Wayne Ming Quan Yap
  • Mark Tan
  • Chun Sing Yu
  • Jacob Yoong-Leong Oh
  • J Orthop.2020 Sep-Oct;21:321-325. S0972-978X(20)30203-8. doi: 10.1016/j.jor.2020.05.018.Epub 2020-06-06.

活動期および潜伏期の結核感染のより良い診断のための候補宿主血清および唾液バイオマーカーの同定

Identification of candidate host serum and saliva biomarkers for a better diagnosis of active and latent tuberculosis infection.
  • Olivia Estévez
  • Luis Anibarro
  • Elina Garet
  • Ángeles Pallares
  • Alberto Pena
  • Carlos Villaverde
  • Víctor Del Campo
  • África González-Fernández
  • PLoS ONE.2020;15(7):e0235859. PONE-D-20-08461. doi: 10.1371/journal.pone.0235859.Epub 2020-07-20.

顎顔面補綴シリコーンエラストマーの機械的特性に対するフィラー粒子の影響。系統的レビューとメタアナリシス

The Influence of Filler Particles on the Mechanical Properties of Maxillofacial Prosthetic Silicone Elastomers: A Systematic Review and Meta-Analysis.
  • Aparna Barman
  • Farah Rashid
  • Taseef Hasan Farook
  • Nafij Bin Jamayet
  • James Dudley
  • Mohd Firdaus Bin Yhaya
  • Mohammad Khursheed Alam
  • Polymers (Basel).2020 Jul;12(7). E1536. doi: 10.3390/polym12071536.Epub 2020-07-12.

CD123免疫染色による円板状エリテマトーデスと毛孔性苔癬における形質細胞性樹状細胞の分布パターンの違い

Different distribution patterns of plasmacytoid dendritic cells in discoid lupus erythematosus and lichen planopilaris demonstrated by CD123 immunostaining.
  • Azadeh Rakhshan
  • Parviz Toossi
  • Maliheh Amani
  • Sahar Dadkhahfar
  • Arash Bagheri Hamidi
  • An Bras Dermatol.2020 May - Jun;95(3):307-313. S0365-0596(20)30087-8. doi: 10.1016/j.abd.2019.11.005.Epub 2020-03-20.

鉄過負荷は肥満児の血糖値の上昇と関連しており、in vitroでは高グルコース誘発性内皮細胞機能障害を悪化させていることが示唆された

Iron overload is related to elevated blood glucose levels in obese children and aggravates high glucose-induced endothelial cell dysfunction in vitro.
  • Wei Wu
  • Jinna Yuan
  • Yu Shen
  • Yunxian Yu
  • Xuefeng Chen
  • Li Zhang
  • Ke Huang
  • Jianying Zhan
  • Guan-Ping Dong
  • Junfen Fu
  • BMJ Open Diabetes Res Care.2020 Jul;8(1). e001426. doi: 10.1136/bmjdrc-2020-001426.

また、出生前低酸素は酸化ストレスの増加を介して高齢子孫の腸間膜動脈の内皮依存性血管拡張に影響を与えた

Prenatal hypoxia affected endothelium-dependent vasodilation in mesenteric arteries of aged offspring via increased oxidative stress.
  • Xueyi Chen
  • Linglu Qi
  • Xiaorong Fan
  • Hehua Tao
  • Mengshu Zhang
  • Qinqin Gao
  • Yanping Liu
  • Ting Xu
  • Pengjie Zhang
  • Hongyu Su
  • Jiaqi Tang
  • Zhice Xu
  • Hypertens. Res..2019 06;42(6):863-875. 10.1038/s41440-018-0181-7. doi: 10.1038/s41440-018-0181-7.Epub 2019-01-07.

鈍性肝・脾臓損傷の非手術的管理:17年間の時間的傾向と転帰の分析

Non-operative management of blunt hepatic and splenic injury: a time-trend and outcome analysis over a period of 17 years.
  • Margot Fodor
  • Florian Primavesi
  • Dagmar Morell-Hofert
  • Veronika Kranebitter
  • Anna Palaver
  • Eva Braunwarth
  • Matthias Haselbacher
  • Ulrich Nitsche
  • Stefan Schmid
  • Michael Blauth
  • Eva Gassner
  • Dietmar Öfner
  • Stefan Stättner
  • World J Emerg Surg.2019;14:29. 249. doi: 10.1186/s13017-019-0249-y.Epub 2019-06-17.

一分子ライブセルイメージングにより、DNAポリメラーゼIVの二重鎖切断修復におけるRecB依存性の機能を明らかにした

Single-molecule live-cell imaging reveals RecB-dependent function of DNA polymerase IV in double strand break repair.
  • Sarah S Henrikus
  • Camille Henry
  • Amy E McGrath
  • Slobodan Jergic
  • John P McDonald
  • Yvonne Hellmich
  • Steven T Bruckbauer
  • Matthew L Ritger
  • Megan E Cherry
  • Elizabeth A Wood
  • Phuong T Pham
  • Myron F Goodman
  • Roger Woodgate
  • Michael M Cox
  • Antoine M van Oijen
  • Harshad Ghodke
  • Andrew Robinson
  • Nucleic Acids Res..2020 Jul;gkaa597. doi: 10.1093/nar/gkaa597.Epub 2020-07-20.

ポリスチレン-b-(エチレン-コ-ブチレン-b-スチレン)表面にα-ヘリカルペプチドデンドライトポリマーを用いて構築されたボトルブラシ状の高効率抗菌コーティング

Bottlebrush-like highly efficient antibacterial coating constructed using α-helical peptide dendritic polymers on the poly(styrene-b-(ethylene-co-butylene)-b-styrene) surface.
  • Yujia Zhang
  • Ke Kang
  • Nanhang Zhu
  • Guohao Li
  • Xiaoxi Zhou
  • Aimin Zhang
  • Qiangying Yi
  • Yao Wu
  • J Mater Chem B.2020 Jul;doi: 10.1039/d0tb01336f.Epub 2020-07-14.

β-ナフトフラボンによる肝細胞における外来物質代謝酵素の誘導。活性、タンパク質およびmRNAレベルの時間依存的変化

Induction of xenobiotic-metabolizing enzymes in hepatocytes by beta-naphthoflavone: Time-dependent changes in activities, protein and mRNA levels.
  • Kateřina Lněničková
  • Lenka Skálová
  • Lucie Stuchlíková
  • Barbora Szotáková
  • Petra Matoušková
  • Acta Pharm.2018 Mar;68(1):75-85. /j/acph.2018.68.issue-1/acph-2018-0005/acph-2018-0005.xml. doi: 10.2478/acph-2018-0005.

ミニ大胸筋切開大動脈弁置換術後の患者コントロール鎮痛ポンプによる0.2%ロピバカインの創傷注入の有効性:無作為化二重盲検プラセボ対照試験

Effectiveness of wound infusion of 0.2% ropivacaine by patient control analgesia pump after minithoracotomy aortic valve replacement: a randomized, double-blind, placebo-controlled trial.
  • Gordan Mijovski
  • Matej Podbregar
  • Juš Kšela
  • Matej Jenko
  • Maja Šoštarič
  • BMC Anesthesiol.2020 Jul;20(1):172. 10.1186/s12871-020-01093-9. doi: 10.1186/s12871-020-01093-9.Epub 2020-07-18.

成人マウスのペルフルオロブタンスルホン酸塩曝露は、甲状腺機能低下症を介して卵巣機能に影響を与え、Akt-mTOR シグナルのダウンレギュレーションを引き起こす

Exposure of adult mice to perfluorobutanesulfonate impacts ovarian functions through hypothyroxinemia leading to down-regulation of Akt-mTOR signaling.
  • Xin-Yuan Cao
  • Juan Liu
  • Ya-Jie Zhang
  • Ya Wang
  • Jian-Wei Xiong
  • Jie Wu
  • Ling Chen
  • Chemosphere.2020 Apr;244:125497. S0045-6535(19)32737-7. doi: 10.1016/j.chemosphere.2019.125497.Epub 2019-11-27.

単一ドメインカメロイド抗体によるベタコロナウイルスの強力な中和の構造的基盤.

Structural Basis for Potent Neutralization of Betacoronaviruses by Single-Domain Camelid Antibodies.
  • Daniel Wrapp
  • Dorien De Vlieger
  • Kizzmekia S Corbett
  • Gretel M Torres
  • Nianshuang Wang
  • Wander Van Breedam
  • Kenny Roose
  • Loes van Schie
  • Markus Hoffmann
  • Stefan Pöhlmann
  • Barney S Graham
  • Nico Callewaert
  • Bert Schepens
  • Xavier Saelens
  • Jason S McLellan
  • Cell.2020 05;181(5):1004-1015.e15. S0092-8674(20)30494-3. doi: 10.1016/j.cell.2020.04.031.Epub 2020-05-05.

マトリックスメタロプロテアーゼ-9活性と動脈硬化パラメータの組み合わせによる抵抗性高血圧におけるスピロノラクトンに対する早期反応の予測

Prediction of the early response to spironolactone in resistant hypertension by the combination of matrix metalloproteinase-9 activity and arterial stiffness parameters.
  • Elena Rodríguez-Sánchez
  • José Alberto Navarro-García
  • Jennifer Aceves-Ripoll
  • Laura González-Lafuente
  • Montserrat Baldan-Martin
  • Fernando de la Cuesta
  • Gloria Alvarez-Llamas
  • María G Barderas
  • Julián Segura
  • Luis M Ruilope
  • Gema Ruiz-Hurtado
  • Eur Heart J Cardiovasc Pharmacother.2020 Jul;pvaa086. doi: 10.1093/ehjcvp/pvaa086.Epub 2020-07-14.

急性リンパ芽球性白血病における13q12.2欠損は、エンハンサーハイジャックを介したFLT3のアップレギュレーションにつながる

13q12.2 deletions in acute lymphoblastic leukemia lead to upregulation of FLT3 through enhancer hijacking.
  • Minjun Yang
  • Setareh Safavi
  • Eleanor L Woodward
  • Nicolas Duployez
  • Linda Olsson-Arvidsson
  • Jonas Ungerbäck
  • Mikael Sigvardsson
  • Marketa Zaliova
  • Jan Zuna
  • Thoas Fioretos
  • Bertil Johansson
  • Karolin H Nord
  • Kajsa Paulsson
  • Blood.2020 May;blood.2019004684. doi: 10.1182/blood.2019004684.Epub 2020-05-08.

RADICL-seqは、ゲノムワイドなRNA-クロマチン相互作用の一般的な原理と細胞型特異的な原理を同定する

RADICL-seq identifies general and cell type-specific principles of genome-wide RNA-chromatin interactions.
  • Alessandro Bonetti
  • Federico Agostini
  • Ana Maria Suzuki
  • Kosuke Hashimoto
  • Giovanni Pascarella
  • Juliette Gimenez
  • Leonie Roos
  • Alex J Nash
  • Marco Ghilotti
  • Christopher J F Cameron
  • Matthew Valentine
  • Yulia A Medvedeva
  • Shuhei Noguchi
  • Eneritz Agirre
  • Kaori Kashi
  • Samudyata
  • Joachim Luginbühl
  • Riccardo Cazzoli
  • Saumya Agrawal
  • Nicholas M Luscombe
  • Mathieu Blanchette
  • Takeya Kasukawa
  • Michiel de Hoon
  • Erik Arner
  • Boris Lenhard
  • Charles Plessy
  • Gonçalo Castelo-Branco
  • Valerio Orlando
  • Piero Carninci
  • Nat Commun.2020 02;11(1):1018. 10.1038/s41467-020-14337-6. doi: 10.1038/s41467-020-14337-6.Epub 2020-02-24.

クッシング病における薬物治療への反応をモニターするための深夜の唾液性コルチゾールの使用

Use of late-night salivary cortisol to monitor response to medical treatment in Cushing's disease.
  • John Newell-Price
  • Rosario Pivonello
  • Antoine Tabarin
  • Maria Fleseriu
  • Przemysław Witek
  • Mônica R Gadelha
  • Stephan Petersenn
  • Libuse Tauchmanova
  • Shoba Ravichandran
  • Pritam Gupta
  • André Lacroix
  • Beverly M K Biller
  • Eur. J. Endocrinol..2020 Feb;182(2):207-217. EJE-19-0695. doi: 10.1530/EJE-19-0695.

プレバイオティクスで強化された脂質ベースの栄養補助食品(LNSp)は、ビフィズス菌の相対的な豊富さを増加させ、栄養不良の乳児から模擬大腸微生物叢で短鎖脂肪酸の生産を向上させます

A prebiotic-enhanced lipid-based nutrient supplement (LNSp) increases Bifidobacterium relative abundance and enhances short-chain fatty acid production in simulated colonic microbiota from undernourished infants.
  • Laeticia Celine Toe
  • Frederiek-Maarten Kerckhof
  • Jana De Bodt
  • Fanny B Morel
  • Jean-Bosco Ouedraogo
  • Patrick Kolsteren
  • Tom Van de Wiele
  • FEMS Microbiol. Ecol..2020 Jul;96(7). fiaa105. doi: 10.1093/femsec/fiaa105.

緊急避妊の使用:米国の非ヒスパニック白人、非ヒスパニック黒人、およびヒスパニック女性の間での意識、態度、および信念の影響

Emergency Contraception Use: The Influence of Awareness, Attitudes, and Beliefs Among Non-Hispanic White, Non-Hispanic Black, and Hispanic Women in the United States.
  • Caroline Heller
  • Krista M Perreira
  • Adele Shartzer
  • Emily M Johnston
  • Brigette Courtot
  • Womens Health Issues.2019 Mar - Apr;29(2):161-169. S1049-3867(18)30355-4. doi: 10.1016/j.whi.2019.01.003.Epub 2019-02-20.

ラット大動脈の収縮力に対するLippia alba精油とその主要成分であるシトラールの血管弛緩作用

Vasorelaxant effect of the Lippia alba essential oil and its major constituent, citral, on the contractility of isolated rat aorta.
  • R E R da Silva
  • L P de Morais
  • A A Silva
  • C M S Bastos
  • Á Pereira-Gonçalves
  • M R Kerntopf
  • I R A Menezes
  • J H Leal-Cardoso
  • R Barbosa
  • Biomed. Pharmacother..2018 Dec;108:792-798. S0753-3322(18)33176-7. doi: 10.1016/j.biopha.2018.09.073.Epub 2018-09-22.

ホスホジエステラーゼ-4阻害剤ロフルミラストは、アルツハイマー病における記憶喪失とうつ病の併存症に対する治療薬として期待されている:APP/PS1トランスジェニックマウスを用いた前臨床試験

The phosphodiesterase-4 inhibitor roflumilast, a potential treatment for the comorbidity of memory loss and depression in Alzheimer's disease: a preclinical study in APP/PS1 transgenic mice.
  • Hao Wang
  • Fang-Fang Zhang
  • Yong Xu
  • Hua-Rong Fu
  • Xiao- Dan Wan
  • Lei Wang
  • Wei Chen
  • Xiao-Yan Xu
  • Yong-Feng Gao
  • Ji-Guo Zhang
  • Han-Ting Zhang
  • Int. J. Neuropsychopharmacol..2020 Jul;pyaa048. doi: 10.1093/ijnp/pyaa048.Epub 2020-07-09.

モノアミン酸化酵素Aをモクロベミドで阻害することにより、MPTP病変を有するマーモセットにおけるL-DOPAの抗パーキンソン作用が増強された

Monoamine oxidase A inhibition with moclobemide enhances the anti-parkinsonian effect of L-DOPA in the MPTP-lesioned marmoset.
  • Adjia Hamadjida
  • Stephen G Nuara
  • Cynthia Kwan
  • Imane Frouni
  • Dominique Bédard
  • Jim C Gourdon
  • Philippe Huot
  • Naunyn Schmiedebergs Arch. Pharmacol..2020 Jul;10.1007/s00210-020-01933-y. doi: 10.1007/s00210-020-01933-y.Epub 2020-07-03.

リスクの低い市中quired合併症性腹腔内感染症を有する成人入院患者における治療パターンと関連する転帰の評価。専門家のガイドラインはどのくらいの頻度で守られているか?

An Evaluation of Treatment Patterns and Associated Outcomes Among Adult Hospitalized Patients With Lower-Risk Community-Acquired Complicated Intra-abdominal Infections: How Often Are Expert Guidelines Followed?
  • Thomas P Lodise
  • Sergey Izmailyan
  • Melanie Olesky
  • Kenneth Lawrence
  • Open Forum Infect Dis.2020 Jul;7(7):ofaa237. ofaa237. doi: 10.1093/ofid/ofaa237.Epub 2020-06-19.

中国浙江省の淡水養殖場、海水養殖場、市場で分離された抗生物質耐性菌と重金属耐性菌の共存と配列型多様性

Co-occurrence of Antibiotic and Heavy Metal Resistance and Sequence Type Diversity of Isolated From at Freshwater Farms, Seawater Farms, and Markets in Zhejiang Province, China.
  • Han Jiang
  • Ting Yu
  • Yuting Yang
  • Shengtao Yu
  • Jiangchun Wu
  • Rumeng Lin
  • Yixian Li
  • Jiehong Fang
  • Cheng Zhu
  • Front Microbiol.2020;11:1294. doi: 10.3389/fmicb.2020.01294.Epub 2020-06-26.

ナイジェリアのカノ州において、診断ツールとしてのアルゴリズムアプローチを用いて、一般的な皮膚疾患の管理における第一線の医療従事者のパフォーマンスを検証した

First-line health care provider performance in the management of common skin diseases using an algorithmic approach as a diagnostic tool in Kano State, Nigeria.
  • Anna Theodora Taal
  • Erik B Post
  • Tijjani Hussaini
  • Augustin Gayus Barminus
  • Tahir Dahiru
  • Res Rep Trop Med.2015;6:85-94. 87600. doi: 10.2147/RRTM.S87600.Epub 2015-10-02.

クローン病患者におけるMagnetic Resonance Enterographyの分類と活動性疾患の定量的評価についてのレビュー

A review of Magnetic Resonance Enterography classification and quantitative evaluation of active disease in patients with Crohn's disease.
  • Laura Maria Minordi
  • Luigi Larosa
  • Alfredo Papa
  • Giovanni Cimino
  • Antonio Bevere
  • Maria Gabriella Brizi
  • Riccardo Manfredi
  • Clin Imaging.2020 Jun;69:50-62. S0899-7071(20)30205-9. doi: 10.1016/j.clinimag.2020.06.006.Epub 2020-06-10.

自閉症スペクトラム障害はCHARGE症候群の一部と考えるべきか?46人の患者を対象とした横断的研究

Should autism spectrum disorder be considered part of CHARGE syndrome? A cross-sectional study of 46 patients.
  • Véronique Abadie
  • Priscilla Hamiaux
  • Stéphanie Ragot
  • Marine Legendre
  • Gaelle Malecot
  • Alexia Burtin
  • Tania Attie-Bitach
  • Stanislas Lyonnet
  • Frédéric Bilan
  • Brigitte Gilbert-Dussardier
  • Laurence Vaivre-Douret
  • Orphanet J Rare Dis.2020 Jun;15(1):136. 10.1186/s13023-020-01421-9. doi: 10.1186/s13023-020-01421-9.Epub 2020-06-03.

海馬硬化症を伴う中側頭葉てんかん患者における診断および手術成績の予測因子としての循環マイクロRNAの発現

Expression of circulating microRNAs as predictors of diagnosis and surgical outcome in patients with mesial temporal lobe epilepsy with hippocampal sclerosis.
  • Enrico Salomao Ioriatti
  • Mucio Luiz Assis Cirino
  • Fermino Sanches Lizarte Neto
  • Tonicarlo Rodrigues Velasco
  • Americo Ceiki Sakamoto
  • Priscila Freitas-Lima
  • Daniela Pretti Cunha Tirapelli
  • Carlos Gilberto Carlotti
  • Epilepsy Res..2020 May;166:106373. S0920-1211(19)30661-8. doi: 10.1016/j.eplepsyres.2020.106373.Epub 2020-05-22.

(Guenee)に対するジンセノサイド誘発殺虫効果を有するアミノ酸、脂肪酸、および炭水化物のメタボロームプロファイル

Amino acid, fatty acid, and carbohydrate metabolomic profiles with ginsenoside-induced insecticidal efficacy against (Guenee).
  • Shuangli Liu
  • Xiaohui Wang
  • Rui Zhang
  • Mingjie Song
  • Nanqi Zhang
  • Wanying Li
  • Yingping Wang
  • Yonghua Xu
  • Lianxue Zhang
  • J Ginseng Res.2020 Jul;44(4):544-551. S1226-8453(18)30335-X. doi: 10.1016/j.jgr.2019.04.006.Epub 2019-04-29.

ラットモデルにおけるホエイ蛋白質濃縮物加水分解物の毒性試験と血圧降下効果、およびペプチドの特性解析

Toxicity study and blood pressure-lowering efficacy of whey protein concentrate hydrolysate in rat models, plus peptide characterization.
  • Fatima A Hussein
  • Shyan Yea Chay
  • Siti Balqis M Ghanisma
  • Mohammad Zarei
  • Shehu M Auwal
  • Azizah A Hamid
  • Wan Zunairah Wan Ibadullah
  • Nazamid Saari
  • J. Dairy Sci..2020 Mar;103(3):2053-2064. S0022-0302(19)31127-0. doi: 10.3168/jds.2019-17462.Epub 2019-12-25.

ラット腎臓における酢酸鉛による酸化ストレスと炎症に対するクリシンの保護効果:生化学的・病理組織学的アプローチ

Protective Effects of Chrysin Against Oxidative Stress and Inflammation Induced by Lead Acetate in Rat Kidneys: a Biochemical and Histopathological Approach.
  • Sefa Kucukler
  • Fulya Benzer
  • Serkan Yildirim
  • Cihan Gur
  • Fatih Mehmet Kandemir
  • Aydin Sukru Bengu
  • Adnan Ayna
  • Cuneyt Caglayan
  • Muhammet Bahaeddin Dortbudak
  • Biol Trace Elem Res.2020 Jun;10.1007/s12011-020-02268-8. doi: 10.1007/s12011-020-02268-8.Epub 2020-06-29.

炎症性サインは、経大動脈的大動脈弁留置後の死亡率の増加と関連している

Inflammatory signatures are associated with increased mortality after transfemoral transcatheter aortic valve implantation.
  • Jedrzej Hoffmann
  • Silvia Mas-Peiro
  • Alexander Berkowitsch
  • Felicitas Boeckling
  • Tina Rasper
  • Konrad Pieszko
  • Roberta De Rosa
  • Jarosław Hiczkiewicz
  • Paweł Burchardt
  • Stephan Fichtlscherer
  • Andreas M Zeiher
  • Stefanie Dimmeler
  • Mariuca Vasa Nicotera
  • ESC Heart Fail.2020 Jul;doi: 10.1002/ehf2.12837.Epub 2020-07-08.

中近東呼吸器症候群を対象とした改良型ワケシニアウイルスアンカラベクターワクチン候補の安全性と免疫原性:非盲検第1相試験

Safety and immunogenicity of a modified vaccinia virus Ankara vector vaccine candidate for Middle East respiratory syndrome: an open-label, phase 1 trial.
  • Till Koch
  • Christine Dahlke
  • Anahita Fathi
  • Alexandra Kupke
  • Verena Krähling
  • Nisreen M A Okba
  • Sandro Halwe
  • Cornelius Rohde
  • Markus Eickmann
  • Asisa Volz
  • Thomas Hesterkamp
  • Alen Jambrecina
  • Saskia Borregaard
  • My L Ly
  • Madeleine E Zinser
  • Etienne Bartels
  • Joseph S H Poetsch
  • Reza Neumann
  • Robert Fux
  • Stefan Schmiedel
  • Ansgar W Lohse
  • Bart L Haagmans
  • Gerd Sutter
  • Stephan Becker
  • Marylyn M Addo
  • Lancet Infect Dis.2020 Jul;20(7):827-838. S1473-3099(20)30248-6. doi: 10.1016/S1473-3099(20)30248-6.Epub 2020-04-21.

ヘムオキシゲナーゼ-1は、活性化Tリンパ球上のLAPおよびGARP発現をアップレギュレーションすることにより、急性冠症候群患者からの障害されたGARPCD4⁺CD25⁺調節性T細胞を回復させる

Heme oxygenase-1 restores impaired GARPCD4⁺CD25⁺ regulatory T cells from patients with acute coronary syndrome by upregulating LAP and GARP expression on activated T lymphocytes.
  • Yuzhou Liu
  • Xiaoqi Zhao
  • Yucheng Zhong
  • Kai Meng
  • Kunwu Yu
  • Huairui Shi
  • Bangwei Wu
  • Hasahya Tony
  • Jianghao Zhu
  • Ruirui Zhu
  • Yudong Peng
  • Yi Mao
  • Peng Cheng
  • Xiaobo Mao
  • Qiutang Zeng
  • Cell. Physiol. Biochem..2015;35(2):553-70. 000369719. doi: 10.1159/000369719.Epub 2015-01-27.

腎移植後にセリアック病を模倣した重度の下痢を引き起こした免疫抑制誘発性クローン性T細胞リンパ増殖性疾患:1例の報告

Immunosuppression-induced clonal T-cell lymphoproliferative disease causing severe diarrhoea mimicking coeliac disease following renal transplantation: a case report.
  • Emily K Glover
  • R Alexander Speight
  • Despina Televantou
  • Stephanie Needham
  • Neil S Sheerin
  • BMC Nephrol.2020 Jun;21(1):220. 10.1186/s12882-020-01884-9. doi: 10.1186/s12882-020-01884-9.Epub 2020-06-10.

非糖尿病性腎性貧血ラットにおけるナトリウム-グルコースコトランスポーター2阻害剤誘発造血効果の確認に失敗した

Failure to confirm a sodium-glucose cotransporter 2 inhibitor-induced hematopoietic effect in non-diabetic rats with renal anemia.
  • Daisuke Yamazaki
  • Yoshio Konishi
  • Takashi Morikawa
  • Hideki Kobara
  • Tsutomu Masaki
  • Hirofumhi Hitomi
  • Kenji Osafune
  • Daisuke Nakano
  • Wararat Kittikulsuth
  • Akira Nishiyama
  • J Diabetes Investig.2019 Dec;doi: 10.1111/jdi.13205.Epub 2019-12-27.

発展途上国7カ国における認知症有病率のシステマティックレビューとメタアナリシス。STRiDEプロジェクト

A systematic review and meta-analysis of dementia prevalence in seven developing countries: A STRiDE project.
  • N Farina
  • A Ibnidris
  • S Alladi
  • A Comas-Herrera
  • E Albanese
  • S Docrat
  • C P Ferri
  • E Freeman
  • I Govia
  • R Jacobs
  • C I Astudillo-Garcia
  • C Musyimi
  • T P Sani
  • M Schneider
  • I Theresia
  • Y Turana
  • M Knapp
  • S Banerjee
  • Glob Public Health.2020 Jul;:1-16. doi: 10.1080/17441692.2020.1792527.Epub 2020-07-13.

ポサコナゾールおよびイトラコナゾール誘発性偽性アルドステロン症の分子機構と他の全身用アゾール系抗真菌薬の評価

Molecular mechanisms of posaconazole- and itraconazole-induced pseudohyperaldosteronism and assessment of other systemically used azole antifungals.
  • Katharina R Beck
  • Lucija Telisman
  • Chris J van Koppen
  • George R Thompson
  • Alex Odermatt
  • J. Steroid Biochem. Mol. Biol..2020 May;199:105605. S0960-0760(19)30695-8. doi: 10.1016/j.jsbmb.2020.105605.Epub 2020-01-23.

政治家の皆様:COVID-19の拡散を最小限に抑えるために協力してください

Politicians: please work together to minimise the spread of COVID-19.
  • David Murdoch
  • Michael Addidle
  • Hanna-Sofia Andersson
  • Brendan Arnold
  • Michelle Balm
  • Jackie Benschop
  • Bryan Betty
  • Mark Birch
  • Max Bloomfield
  • Cheryl Brunton
  • Andrew Burns
  • Stephen Chambers
  • Lynley Cook
  • Simon Dalton
  • Harvey Duncan
  • Juliet Elvy
  • Richard Everts
  • Joshua Freeman
  • Nigel French
  • Kate Grimwade
  • David Hammer
  • David Hayman
  • David Holland
  • Ben Hudson
  • Paul Huggan
  • Rosemary Ikram
  • Susan Jack
  • Matthew Kelly
  • Iain Lamont
  • Michael Maze
  • Gary McAuliffe
  • Stephen McBride
  • Sarah Metcalf
  • Susan Morpeth
  • Arthur Morris
  • Samantha Murton
  • Ramon Pink
  • Alan Pithie
  • Martin Pitout
  • Patricia Priest
  • Nigel Raymond
  • Kerry Read
  • Stephen Ritchie
  • Matthew Rogers
  • Philip Schroeder
  • Susan Taylor
  • James Taylor
  • Mark Thomas
  • Arlo Upton
  • James Ussher
  • Anja Werno
  • Siouxsie Wiles
  • N. Z. Med. J..2020 03;133(1511):7-8. Epub 2020-03-13.

形態学的・生理学的・分子学的データに基づく謎の種複合体Saprolegnia diclina-Saprolegnia parasiticaの再評価

Re-evaluation of the enigmatic species complex Saprolegnia diclina-Saprolegnia parasitica based on morphological, physiological and molecular data.
  • Javier Diéguez-Uribeondo
  • Juan M Fregeneda-Grandes
  • Lage Cerenius
  • Elena Pérez-Iniesta
  • José Miguel Aller-Gancedo
  • M Teresa Tellería
  • Kenneth Söderhäll
  • María P Martín
  • Fungal Genet. Biol..2007 Jul;44(7):585-601. S1087-1845(07)00050-3. doi: 10.1016/j.fgb.2007.02.010.Epub 2007-03-06.

バイオインフォマティクス解析により、ヒトアデノウイルス3型(HAdV-3)の4つの主要なヘキソンバリアントが、HAdV-3呼吸器感染症に対するワクチンやsiRNAベースの治療法開発のための潜在的な株であることが明らかになりました

Bioinformatics analysis reveals four major hexon variants of human adenovirus type-3 (HAdV-3) as the potential strains for development of vaccine and siRNA-based therapeutics against HAdV-3 respiratory infections.
  • Somnath Panda
  • Urmila Banik
  • Arun K Adhikary
  • Infect. Genet. Evol..2020 Jun;85:104439. S1567-1348(20)30270-7. doi: 10.1016/j.meegid.2020.104439.Epub 2020-06-23.

安定型および不安定型冠動脈疾患患者における血漿ミエロペルオキシダーゼ値と血清高密度リポ蛋白質関連パラオキソナーゼ-1値との性差相関

Gender-specific correlation between plasma myeloperoxidase levels and serum high-density lipoprotein-associated paraoxonase-1 levels in patients with stable and unstable coronary artery disease.
  • Kei Yunoki
  • Takahiko Naruko
  • Mayumi Inaba
  • Takeshi Inoue
  • Masashi Nakagawa
  • Kenichi Sugioka
  • Masahiko Ohsawa
  • Yoko Iwasa
  • Ryushi Komatsu
  • Akira Itoh
  • Kazuo Haze
  • Minoru Yoshiyama
  • Anton E Becker
  • Makiko Ueda
  • Atherosclerosis.2013 Dec;231(2):308-14. S0021-9150(13)00513-3. doi: 10.1016/j.atherosclerosis.2013.08.037.Epub 2013-10-08.

miR-137とその標的となるT型カルシウム3.1チャネルは、カルシニューリン/NFAT経路を制御することにより、微小重力模擬ラットにおける脳血管平滑筋細胞の分化・増殖を調節していることを明らかにした

miR-137 and its target T-type Ca 3.1 channel modulate dedifferentiation and proliferation of cerebrovascular smooth muscle cells in simulated microgravity rats by regulating calcineurin/NFAT pathway.
  • Bin Zhang
  • Li Chen
  • Yun-Gang Bai
  • Ji-Bo Song
  • Jiu-Hua Cheng
  • Hong-Zhe Ma
  • Jin Ma
  • Man-Jiang Xie
  • Cell Prolif..2020 Mar;53(3):e12774. doi: 10.1111/cpr.12774.Epub 2020-02-08.

転移性小細胞肺癌に対してアファチニブによる治療を行い、その後上行結腸およびシグモイド結腸にまれな転移病変を発症した注目すべき症例

A noteworthy treatment of metastatic small-cell lung cancer with afatinib, followed by subsequent development of rare metastatic lesions in the ascending and sigmoid colon.
  • Shih-Chuan Hsiao
  • Yi-Hsien Chen
  • Ching-Chu Lo
  • Ching-I Lin
  • Cancer Rep (Hoboken).2020 Jun;3(3):e1243. doi: 10.1002/cnr2.1243.Epub 2020-03-12.

うつ病に対する新しい治療法(MEmory Specificity Training, MEST)についての簡単な臨床報告:2つのパイロットランダム化比較試験の要約

A brief clinical report documenting a novel therapeutic technique (MEmory Specificity Training, MEST) for depression: a summary of two pilot randomized controlled trials.
  • Mahsa Sadat Zia
  • Elham Afkhami
  • Hamid Taher Neshat-Doost
  • Mahgol Tavakoli
  • Hossein Ali Mehrabi Kooshki
  • Laura Jobson
  • Behav Cogn Psychother.2020 Jul;:1-6. S1352465820000417. doi: 10.1017/S1352465820000417.Epub 2020-07-20.

デング熱流行の予測因子としての媒介蚊の幼虫指数。スリランカのコロンボとカンディの地区における昆虫学的パラメータに基づくデング熱流行管理のためのアプローチ

Larval Indices of Vector Mosquitoes as Predictors of Dengue Epidemics: An Approach to Manage Dengue Outbreaks Based on Entomological Parameters in the Districts of Colombo and Kandy, Sri Lanka.
  • Lahiru Udayanga
  • Subashinie Aryaprema
  • Nayana Gunathilaka
  • M C M Iqbal
  • Thilan Fernando
  • W Abeyewickreme
  • Biomed Res Int.2020;2020:6386952. doi: 10.1155/2020/6386952.Epub 2020-06-16.

B型肝炎ウイルス複製の阻害剤としてのアミド含有α-ヒドロキシトロポロン類

Amide-containing α-hydroxytropolones as inhibitors of hepatitis B virus replication.
  • Qilan Li
  • Elena Lomonosova
  • Maureen J Donlin
  • Feng Cao
  • Austin O'Dea
  • Brienna Milleson
  • Alex J Berkowitz
  • John-Charles Baucom
  • John P Stasiak
  • Daniel V Schiavone
  • Rudolf G Abdelmessih
  • Anastasiya Lyubimova
  • Americo J Fraboni
  • Lauren P Bejcek
  • Juan A Villa
  • Emilio Gallicchio
  • Ryan P Murelli
  • John E Tavis
  • Antiviral Res..2020 05;177:104777. S0166-3542(20)30076-0. doi: 10.1016/j.antiviral.2020.104777.Epub 2020-03-23.

種間体細胞核移植により初めてクローン化されたバクトリアンラクダ(Camelus bactrianus)の子牛。絶滅の危機に瀕している野生のバクトリアンラクダの保護に向けた一歩

First cloned Bactrian camel (Camelus bactrianus) calf produced by interspecies somatic cell nuclear transfer: A step towards preserving the critically endangered wild Bactrian camels.
  • Nisar Ahmad Wani
  • Binoy S Vettical
  • Seung B Hong
  • PLoS ONE.2017;12(5):e0177800. PONE-D-16-47958. doi: 10.1371/journal.pone.0177800.Epub 2017-05-17.

血管芽細胞腫とvon Hippel-Lindau病:遺伝的背景、疾患のスペクトル、脳外科的治療

Hemangioblastoma and von Hippel-Lindau disease: genetic background, spectrum of disease, and neurosurgical treatment.
  • Jan-Helge Klingler
  • Sven Gläsker
  • Birke Bausch
  • Horst Urbach
  • Tobias Krauss
  • Cordula A Jilg
  • Christine Steiert
  • Alexander Puzik
  • Elke Neumann-Haefelin
  • Fruzsina Kotsis
  • Hansjürgen Agostini
  • Hartmut P H Neumann
  • Jürgen Beck
  • Childs Nerv Syst.2020 Jun;10.1007/s00381-020-04712-5. doi: 10.1007/s00381-020-04712-5.Epub 2020-06-07.

マルチチャンネル体腔内インピーダンスおよびpHモニタリング。小児の基準値への一歩

Multichannel Intraluminal Impedance and pH Monitoring: A Step Towards Pediatric Reference Values.
  • Francesco Cresi
  • Elena Andrea Cester
  • Silvia Salvatore
  • Domenico Umberto De Rose
  • Antonio Ripepi
  • Anna Maria Magistà
  • Claudia Fontana
  • Elena Maggiora
  • Alessandra Coscia
  • Ruggiero Francavilla
  • Fernanda Cristofori
  • J Neurogastroenterol Motil.2020 07;26(3):370-377. jnm19205. doi: 10.5056/jnm19205.

多発性硬化症モデルラットにおけるヒト脂肪由来幹細胞(ADSCs)とプレグネノロンを用いた脱髄性冠状動脈の再骨髄化の改善

Improvement of Remyelination in Demyelinated Corpus Callosum Using Human Adipose-Derived Stem Cells (hADSCs) and Pregnenolone in the Cuprizone Rat Model of Multiple Sclerosis.
  • Rasoul Ganji
  • Shahnaz Razavi
  • Nazem Ghasemi
  • Mohammad Mardani
  • J. Mol. Neurosci..2020 Jul;70(7):1088-1099. 10.1007/s12031-020-01515-w. doi: 10.1007/s12031-020-01515-w.Epub 2020-04-21.

コロナウイルス病2019(COVID-19)とあなたの放射線科診療。症例のトリアージ、人員配置戦略、および収益の懸念への対処

Coronavirus Disease 2019 (COVID-19) and Your Radiology Practice: Case Triage, Staffing Strategies, and Addressing Revenue Concerns.
  • Christoph I Lee
  • Sabiha Raoof
  • Samir B Patel
  • Robert S Pyatt
  • David S Kirsch
  • Mahmud Mossa-Basha
  • Michael Recht
  • Ruth C Carlos
  • J Am Coll Radiol.2020 Jun;17(6):752-754. S1546-1440(20)30421-X. doi: 10.1016/j.jacr.2020.04.025.Epub 2020-04-27.

コーンビームコンピュータトモグラフィーと前処置のコンピュータトモグラフィーの画像登録は副腎静脈の局所化と副腎静脈サンプリングにおける放射線量の低減に役立つ

Image Registration of Cone-Beam Computer Tomography and Preprocedural Computer Tomography Aids in Localization of Adrenal Veins and Decreasing Radiation Dose in Adrenal Vein Sampling.
  • Wendy M H Busser
  • Mark J Arntz
  • Sjoerd F M Jenniskens
  • Jaap Deinum
  • Yvonne L Hoogeveen
  • Frank de Lange
  • Leo J Schultze Kool
  • Cardiovasc Intervent Radiol.2015 Aug;38(4):993-7. doi: 10.1007/s00270-014-0969-z.Epub 2014-09-20.

食道切除既往歴のある患者に対し、正中胸骨切開術を介したオフポンプ冠動脈バイパスグラフト術を施行した症例の報告

Off-pump coronary artery bypass grafting via median sternotomy in a patient with a history of esophagectomy with substernal gastric tube reconstruction: report of a case.
  • Noriyuki Kashiyama
  • Koichi Toda
  • Shigeru Miyagawa
  • Hiroyuki Nishi
  • Yasushi Yoshikawa
  • Satsuki Fukushima
  • Daisuke Yoshioka
  • Kawamura Masashi
  • Tetsuya Saito
  • Yoshiki Sawa
  • Surg. Today.2015 Sep;45(9):1190-3. doi: 10.1007/s00595-014-1057-3.Epub 2014-10-29.

肺がん細胞におけるc-Mycユビキチン-プロテアソーム分解を媒介する新規c-Myc標的化合物-ビス(5-エチル-2-ヒドロキシベンジル)メチルアミン

Novel c-Myc-Targeting Compound , -Bis (5-Ethyl-2-Hydroxybenzyl) Methylamine for Mediated c-Myc Ubiquitin-Proteasomal Degradation in Lung Cancer Cells.
  • Nicharat Sriratanasak
  • Korrakod Petsri
  • Apirat Laobuthee
  • Worawat Wattanathana
  • Chanida Vinayanuwattikun
  • Sudjit Luanpitpong
  • Pithi Chanvorachote
  • Mol. Pharmacol..2020 Aug;98(2):130-142. mol.120.119719. doi: 10.1124/mol.120.119719.Epub 2020-06-02.

イッペイ・ライク3(ypel3)は、神経周囲のグリアの骨髄化とグリアの発生に必要な新規遺伝子であることが明らかになった

yippee like 3 (ypel3) is a novel gene required for myelinating and perineurial glia development.
  • Bernardo Blanco-Sánchez
  • Aurélie Clément
  • Sara J Stednitz
  • Jennifer Kyle
  • Judy L Peirce
  • Marcie McFadden
  • Jeremy Wegner
  • Jennifer B Phillips
  • Ellen Macnamara
  • Yan Huang
  • David R Adams
  • Camilo Toro
  • William A Gahl
  • May Christine V Malicdan
  • Cynthia J Tifft
  • Erika M Zink
  • Kent J Bloodsworth
  • Kelly G Stratton
  • David M Koeller
  • Thomas O Metz
  • Philip Washbourne
  • Monte Westerfield
  • PLoS Genet..2020 Jun;16(6):e1008841. PGENETICS-D-19-01561. doi: 10.1371/journal.pgen.1008841.Epub 2020-06-16.

Porphyromonas gingivalisからのIX型分泌系の構成要素であるPorMの異なる構築物の結晶化シャペロンとして使用されたカメロイドナノボディ

Camelid nanobodies used as crystallization chaperones for different constructs of PorM, a component of the type IX secretion system from Porphyromonas gingivalis.
  • Yoan Duhoo
  • Jennifer Roche
  • Thi Trang Nhung Trinh
  • Aline Desmyter
  • Anaïs Gaubert
  • Christine Kellenberger
  • Christian Cambillau
  • Alain Roussel
  • Philippe Leone
  • Acta Crystallogr F Struct Biol Commun.2017 05;73(Pt 5):286-293. S2053230X17005969. doi: 10.1107/S2053230X17005969.Epub 2017-04-26.

線条体濃縮タンパク質チロシンホスファターゼシグナル伝達の破綻は、敗血症関連脳症のマウスモデルにおける記憶障害に寄与している可能性がある

Disruption of Striatal-Enriched Protein Tyrosine Phosphatase Signaling Might Contribute to Memory Impairment in a Mouse Model of Sepsis-Associated Encephalopathy.
  • Man-Man Zong
  • Hong-Mei Yuan
  • Xue He
  • Zhi-Qiang Zhou
  • Xiao-Dong Qiu
  • Jian-Jun Yang
  • Mu-Huo Ji
  • Neurochem. Res..2019 Dec;44(12):2832-2842. 10.1007/s11064-019-02905-2. doi: 10.1007/s11064-019-02905-2.Epub 2019-11-06.

HLA-A2に強い親和性を持つ合成腫瘍特異的抗原性ペプチドは、CD8 T細胞を活性化することで抗乳がん免疫応答を誘導します

Synthetic tumor-specific antigenic peptides with a strong affinity to HLA-A2 elicit anti-breast cancer immune response through activating CD8 T cells.
  • Wei Shi
  • Qianqian Qiu
  • Zhenzhen Tong
  • Weiwei Guo
  • Feng Zou
  • Ziying Feng
  • Yao Wang
  • Wenlong Huang
  • Hai Qian
  • Eur J Med Chem.2020 Mar;189:112051. S0223-5234(20)30018-0. doi: 10.1016/j.ejmech.2020.112051.Epub 2020-01-11.

全長腫瘍抗原mRNAをエレクトロポレーションした抗原提示型腫瘍細胞株を用いた腫瘍特異的T細胞受容体の機能性の迅速評価

Rapid Assessment of Functional Avidity of Tumor-Specific T Cell Receptors Using an Antigen-Presenting Tumor Cell Line Electroporated with Full-Length Tumor Antigen mRNA.
  • Diana Campillo-Davo
  • Maarten Versteven
  • Gils Roex
  • Hans De Reu
  • Sanne van der Heijden
  • Sébastien Anguille
  • Zwi N Berneman
  • Viggo F I Van Tendeloo
  • Eva Lion
  • Cancers (Basel).2020 Jan;12(2). E256. doi: 10.3390/cancers12020256.Epub 2020-01-21.

変形性膝関節症のヒト膝内側メニスカスの根元細胞と角細胞の細胞特性と機械的ストレスへの応答の違い

Differences between the root and horn cells of the human medial meniscus from the osteoarthritic knee in cellular characteristics and responses to mechanical stress.
  • Yuki Okazaki
  • Takayuki Furumatsu
  • Yusuke Kamatsuki
  • Keiichiro Nishida
  • Yoshihisa Nasu
  • Ryuichi Nakahara
  • Taichi Saito
  • Toshifumi Ozaki
  • J Orthop Sci.2020 Mar;S0949-2658(20)30067-1. doi: 10.1016/j.jos.2020.02.015.Epub 2020-03-26.

成人の肥満対策に対するマグネシウムサプリメントの効果:無作為化比較試験のシステマティックレビューと用量反応メタアナリシス

The effects of magnesium supplementation on obesity measures in adults: a systematic review and dose-response meta-analysis of randomized controlled trials.
  • Mohammadreza Askari
  • Hadis Mozaffari
  • Alireza Jafari
  • Mahtab Ghanbari
  • Manije Darooghegi Mofrad
  • Crit Rev Food Sci Nutr.2020 Jul;:1-17. doi: 10.1080/10408398.2020.1790498.Epub 2020-07-11.

運動はストレスを受けたラットの三叉神経後部核におけるCGRPの発現を増加させ、片頭痛に対する脆弱性を高めることが示唆された

Physical exercise enhances vulnerability to migraine headache associated with CGRP up-expression in trigeminal nucleus caudalis of stressed rats.
  • Razieh Kooshki
  • Mehdi Abbasnejad
  • Ali Shamsizadeh
  • Maryam Raoof
  • Khadijeh Askari-Zahabi
  • Saeed Esmaeili-Mahani
  • Neurol. Res..2020 Jul;:1-7. doi: 10.1080/01616412.2020.1794243.Epub 2020-07-18.

良い隣人、悪い隣人:海馬の頻繁なネットワーク近傍マッピングは、414人の被験者コホートにおける人間の知能のいくつかの構造的要因を明らかにした

Good neighbors, bad neighbors: the frequent network neighborhood mapping of the hippocampus enlightens several structural factors of the human intelligence on a 414-subject cohort.
  • Máté Fellner
  • Bálint Varga
  • Vince Grolmusz
  • Sci Rep.2020 Jul;10(1):11967. 10.1038/s41598-020-68914-2. doi: 10.1038/s41598-020-68914-2.Epub 2020-07-20.

ヒト病原性鉤虫Ancylostoma ceylanicumに対する駆虫活性のためのDalea parryi(マメ科)代謝物の調査

Investigation of Dalea parryi (Fabaceae) metabolites for anthelmintic activity against the human pathogenic hookworm Ancylostoma ceylanicum.
  • Gil Belofsky
  • Lindsay Engels
  • Victoria McPherson
  • Katherine Nash
  • Kiah Sullivan
  • Brendon Torrey
  • Cassandra Ripley
  • Angel Coria
  • Teresa Bicchieri
  • Blaise Dondji
  • Phytochemistry.2020 Jul;177:112423. S0031-9422(20)30143-6. doi: 10.1016/j.phytochem.2020.112423.Epub 2020-07-17.

ロシアにおける淡水産ムール貝(Unionidae)の統合的分類学、生物地理学、保全

Integrative taxonomy, biogeography and conservation of freshwater mussels (Unionidae) in Russia.
  • Ivan N Bolotov
  • Alexander V Kondakov
  • Ekaterina S Konopleva
  • Ilya V Vikhrev
  • Olga V Aksenova
  • Andrey S Aksenov
  • Yulia V Bespalaya
  • Alexey V Borovskoy
  • Petr P Danilov
  • Gennady A Dvoryankin
  • Mikhail Y Gofarov
  • Mikhail B Kabakov
  • Olga K Klishko
  • Yulia S Kolosova
  • Artem A Lyubas
  • Alexander P Novoselov
  • Dmitry M Palatov
  • Grigory N Savvinov
  • Nikolay M Solomonov
  • Vitaly M Spitsyn
  • Svetlana E Sokolova
  • Alena A Tomilova
  • Elsa Froufe
  • Arthur E Bogan
  • Manuel Lopes-Lima
  • Alexander A Makhrov
  • Maxim V Vinarski
  • Sci Rep.2020 Feb;10(1):3072. 10.1038/s41598-020-59867-7. doi: 10.1038/s41598-020-59867-7.Epub 2020-02-20.

模擬微小重力および過重力による心筋細胞のカルシウムシグナル伝達の変化

Alteration of calcium signalling in cardiomyocyte induced by simulated microgravity and hypergravity.
  • Caizhi Liu
  • Guohui Zhong
  • Yuezhang Zhou
  • Yuchen Yang
  • Yingjun Tan
  • Yuheng Li
  • Xingcheng Gao
  • Weijia Sun
  • Jianwei Li
  • Xiaoyan Jin
  • Dengchao Cao
  • Xinxin Yuan
  • Zizhong Liu
  • Shuai Liang
  • Youyou Li
  • Ruikai Du
  • Yinlong Zhao
  • Jianqi Xue
  • Dingsheng Zhao
  • Jinping Song
  • Shukuan Ling
  • Yingxian Li
  • Cell Prolif..2020 Mar;53(3):e12783. doi: 10.1111/cpr.12783.Epub 2020-02-26.

空間的不確実性は、視覚的注意の分布を改善し、意識的な報告のための感覚情報の利用可能性を向上させる

Spatial uncertainty improves the distribution of visual attention and the availability of sensory information for conscious report.
  • Stefano Lasaponara
  • Mario Pinto
  • Michele Pellegrino
  • Ludovica Caratelli
  • Clelia Rossi-Arnaud
  • Vincenzo Cestari
  • Marco Costanzi
  • Fabrizio Doricchi
  • Exp Brain Res.2020 Jul;10.1007/s00221-020-05862-3. doi: 10.1007/s00221-020-05862-3.Epub 2020-07-02.

Limnospira indica PCC8005のフォトバイオリアクターでの成長:ISSと地上実験のモデルとシミュレーション

Limnospira indica PCC8005 growth in photobioreactor: model and simulation of the ISS and ground experiments.
  • Laurent Poughon
  • Céline Laroche
  • Catherine Creuly
  • Claude-Gilles Dussap
  • Christel Paille
  • Christophe Lasseur
  • Pieter Monsieurs
  • Wietse Heylen
  • Ilse Coninx
  • Felice Mastroleo
  • Natalie Leys
  • Life Sci Space Res (Amst).2020 May;25:53-65. S2214-5524(20)30015-8. doi: 10.1016/j.lssr.2020.03.002.Epub 2020-03-13.

将来の宇宙ミッションに向けた臨床試験の設計は、地球上での臨床試験の実施方法を変えるための道筋となる

Designing clinical trials for future space missions as a pathway to changing how clinical trials are conducted on Earth.
  • Mona Nasser
  • Nicholas Peres
  • Jacqui Knight
  • Agatha Haines
  • Charlie Young
  • Diego Maranan
  • Julian Wright
  • Philip Carvil
  • Karen Robinson
  • Matthew Westmore
  • Joanna Griffin
  • Matthew Halkes
  • J Evid Based Med.2020 May;13(2):153-160. doi: 10.1111/jebm.12391.Epub 2020-05-25.

嚢胞性線維症患者におけるキノロン代謝物の形成とクリアランスが健康なボランティアと比較して増加していることを示す最初の集団薬物動態解析

First population pharmacokinetic analysis showing increased quinolone metabolite formation and clearance in patients with cystic fibrosis compared to healthy volunteers.
  • Yuanyuan Jiao
  • Tae Hwan Kim
  • Xun Tao
  • Martina Kinzig
  • Cornelia B Landersdorfer
  • Stefanie K Drescher
  • Dhruvitkumar S Sutaria
  • Bartolome Moya
  • Ulrike Holzgrabe
  • Fritz Sörgel
  • Jürgen B Bulitta
  • Eur J Pharm Sci.2018 Oct;123:416-428. S0928-0987(18)30358-0. doi: 10.1016/j.ejps.2018.07.054.Epub 2018-08-01.

尋常性にきび治療におけるテトラサイクリン系抗生物質とスピロノラクトンの処方パターンを先進医療従事者と医師の間で比較分析した

Comparative analysis of prescribing patterns of tetracycline class antibiotics and spironolactone between advanced practice providers and physicians in the treatment of acne vulgaris.
  • Anthony K Guzman
  • John S Barbieri
  • J. Am. Acad. Dermatol..2020 Jun;S0190-9622(20)31141-5. doi: 10.1016/j.jaad.2020.06.044.Epub 2020-06-16.

耳鼻咽喉科医のための COVID-19 の最新情報 - 耳鼻咽喉科および頸部顔面外科(ABORL-CCF)のブラジル協会のポジションステートメント

An update on COVID-19 for the otorhinolaryngologist - a Brazilian Association of Otolaryngology and Cervicofacial Surgery (ABORL-CCF) Position Statement.
  • Joel Lavinsky
  • Eduardo Macoto Kosugi
  • Eduardo Baptistella
  • Renato Roithmann
  • Eduardo Dolci
  • Thais Knoll Ribeiro
  • Bruno Rossini
  • Fabrizio Ricci Romano
  • Rebecca Christina Kathleen Maunsell
  • Edson Ibrahim Mitre
  • Rui Imamura
  • Adriana Hachiya
  • Carlos Takahiro Chone
  • Luciana Miwa Nita Watanabe
  • Marco Aurélio Fornazieri
  • Marcus Miranda Lessa
  • Geraldo Druck Sant'Anna
  • Braz J Otorhinolaryngol.2020 May - Jun;86(3):273-280. S1808-8694(20)30037-9. doi: 10.1016/j.bjorl.2020.04.002.Epub 2020-04-11.

心臓外科手術患者における室温対体温での4%アルブミン500mLボーラスの血行動態と体温効果の比較

Comparison of the Hemodynamic and Temperature Effects of a 500-mL Bolus of 4% Albumin at Room Versus Body Temperature in Cardiac Surgery Patients.
  • Fumitaka Yanase
  • Laurent Bitker
  • Luca Lucchetta
  • Thummaporn Naorungroj
  • Salvatore L Cutuli
  • Eduardo A Osawa
  • Emmanuel Canet
  • Anthony Wilson
  • Glenn M Eastwood
  • Michael Bailey
  • Rinaldo Bellomo
  • J. Cardiothorac. Vasc. Anesth..2020 Jun;S1053-0770(20)30586-3. doi: 10.1053/j.jvca.2020.06.045.Epub 2020-06-18.

ラットの坐骨神経を慢性的に圧迫すると、脊髄の前角と後角でミクログリアの活性化モードが異なることが明らかになった

Chronic constriction injury of the sciatic nerve in rats causes different activation modes of microglia between the anterior and posterior horns of the spinal cord.
  • Tasuku Nishihara
  • Junya Tanaka
  • Keisuke Sekiya
  • Yuki Nishikawa
  • Naoki Abe
  • Taisuke Hamada
  • Sakiko Kitamura
  • Keizo Ikemune
  • Shinichiro Ochi
  • Mohammed E Choudhury
  • Hajime Yano
  • Toshihiro Yorozuya
  • Neurochem. Int..2020 03;134:104672. S0197-0186(19)30340-7. doi: 10.1016/j.neuint.2020.104672.Epub 2020-01-09.

ベナンの葉の抗酸化作用と酵素(A-アミラーゼ、B-グルコシダーゼ)阻害作用を探る

Exploring Antioxidant and Enzymes (A-Amylase and B-Glucosidase) Inhibitory Activity of and Leaves from Benin.
  • Michaelle Chokki
  • Mihaela Cudălbeanu
  • Cheikna Zongo
  • Durand Dah-Nouvlessounon
  • Ioana Otilia Ghinea
  • Bianca Furdui
  • Robert Raclea
  • Aly Savadogo
  • Lamine Baba-Moussa
  • Sorin Marius Avamescu
  • Rodica Mihaela Dinica
  • Farid Baba-Moussa
  • Foods.2020 Apr;9(4). E434. doi: 10.3390/foods9040434.Epub 2020-04-04.

マンノ--サイクロペリトールは、ヒトα-マンノシダーゼの活性に基づいたタンパク質プロファイリングを可能にし、新しいゴルジマンノシダーゼII阻害剤の発見を可能にします

Manno--cyclophellitols Enable Activity-Based Protein Profiling of Human α-Mannosidases and Discovery of New Golgi Mannosidase II Inhibitors.
  • Zachary Armstrong
  • Chi-Lin Kuo
  • Daniël Lahav
  • Bing Liu
  • Rachel Johnson
  • Thomas J M Beenakker
  • Casper de Boer
  • Chung-Sing Wong
  • Erwin R van Rijssel
  • Marjoke F Debets
  • Bogdan I Florea
  • Colin Hissink
  • Rolf G Boot
  • Paul P Geurink
  • Huib Ovaa
  • Mario van der Stelt
  • Gijsbert M van der Marel
  • Jeroen D C Codée
  • Johannes M F G Aerts
  • Liang Wu
  • Herman S Overkleeft
  • Gideon J Davies
  • J. Am. Chem. Soc..2020 Jul;doi: 10.1021/jacs.0c03880.Epub 2020-07-16.

ドナー特異的キメラ抗原受容体トレッグは、ナイーブだが感作されていないアログラフトレシピエントの拒絶反応を制限する

Donor-specific chimeric antigen receptor Tregs limit rejection in naive but not sensitized allograft recipients.
  • Antoine Sicard
  • Caroline Lamarche
  • Madeleine Speck
  • May Wong
  • Isaac Rosado-Sánchez
  • Mathilde Blois
  • Nicolas Glaichenhaus
  • Majid Mojibian
  • Megan K Levings
  • Am. J. Transplant..2020 06;20(6):1562-1573. doi: 10.1111/ajt.15787.Epub 2020-02-11.

UHPLC-MS/MSによるラット血漿中の大黄ゼチョンピルの19種類の化合物の同時測定と薬物動態研究への応用

Simultaneous determination of nineteen compounds of Dahuang zhechong pill in rat plasma by UHPLC-MS/MS and its application in a pharmacokinetic study.
  • Li Wu
  • Shali Du
  • Furong Yang
  • Zihui Ni
  • Zhipeng Chen
  • Xiao Liu
  • Yulan Wang
  • Qigang Zhou
  • Weidong Li
  • Kunming Qin
  • J. Chromatogr. B Analyt. Technol. Biomed. Life Sci..2020 May;1151:122200. S1570-0232(20)30028-3. doi: 10.1016/j.jchromb.2020.122200.Epub 2020-05-30.

日本人2型糖尿病患者におけるサルコペニアの診断におけるBMIの有意性は、歩行速度の遅さと同等である。外来臨床データを用いた横断的研究.

Significance of BMI for diagnosing sarcopenia is equivalent to slow gait speed in Japanese subjects with type 2 diabetes: Cross-sectional study using outpatient clinical data.
  • Shuhei Nakanishi
  • Masahiro Iwamoto
  • Hisanori Shinohara
  • Hideyuki Iwamoto
  • Hideaki Kaneto
  • J Diabetes Investig.2020 Jul;doi: 10.1111/jdi.13366.Epub 2020-07-19.

2011年の食品医薬品局通知の前後におけるストレス性尿失禁に対するメッシュ利用の傾向:FPMRS認定医師と非FPMRS認定医師の間で:州全体の全医療機関のデータベース分析

Trends of Mesh Utilization for Stress Urinary Incontinence Before and After the 2011 Food and Drug Administration Notification Between FPMRS-certified and Non-FPMRS-certified physicians: a Statewide All-payer Database Analysis.
  • Alexandra R Siegal
  • Zhenyue Huang
  • Michael D Gross
  • Sina Mehraban-Far
  • Steven J Weissbart
  • Jason M Kim
  • Urology.2020 Jul;S0090-4295(20)30818-9. doi: 10.1016/j.urology.2020.06.053.Epub 2020-07-11.

臨床における心臓埋め込み型電子機器の遠隔フォローアップの実施:組織的な意味合いとリソース消費

Implementation of remote follow-up of cardiac implantable electronic devices in clinical practice: organizational implications and resource consumption.
  • Massimiliano Maines
  • Giancarlo Tomasi
  • Paolo Moggio
  • Francesco Peruzza
  • Domenico Catanzariti
  • Carlo Angheben
  • Marzia Simoncelli
  • Massimo Degiampietro
  • Lucio Piffer
  • Sergio Valsecchi
  • Maurizio Del Greco
  • J Cardiovasc Med (Hagerstown).2020 Jun;doi: 10.2459/JCM.0000000000001011.Epub 2020-06-29.

CDR3αは、一次感染における免疫優勢なエプスタインバーウイルス(EBV)BRLF1特異的CD8 T細胞受容体レパートリーの選択を駆動する

CDR3α drives selection of the immunodominant Epstein Barr virus (EBV) BRLF1-specific CD8 T cell receptor repertoire in primary infection.
  • Larisa Kamga
  • Anna Gil
  • Inyoung Song
  • Robin Brody
  • Dario Ghersi
  • Nuray Aslan
  • Lawrence J Stern
  • Liisa K Selin
  • Katherine Luzuriaga
  • PLoS Pathog..2019 11;15(11):e1008122. PPATHOGENS-D-19-01650. doi: 10.1371/journal.ppat.1008122.Epub 2019-11-25.

ラットおよびヒト血球における心血管パラメータの障害

Disorders on cardiovascular parameters in rats and in human blood cells caused by Lachesis acrochorda snake venom.
  • Karen Leonor Angel-Camilo
  • Jimmy Alexander Guerrero-Vargas
  • Emanuella Feitosa de Carvalho
  • Karine Lima Silva
  • Rodrigo José Bezerra de Siqueira
  • Lyara Barbosa Nogueira Freitas
  • João Antônio Costa de Sousa
  • Mario Rogério Lima Mota
  • Armênio Aguiar Dos Santos
  • Ana Gisele da Costa Neves Ferreira
  • Alexandre Havt
  • Luzia Kalyne Almeida Moreira Leal
  • Pedro Jorge Caldas Magalhães
  • Toxicon.2020 Jun;S0041-0101(20)30288-9. doi: 10.1016/j.toxicon.2020.06.009.Epub 2020-06-22.

鍼灸治療は、mTORC1-ULK1-FUNDC1経路を介したマイトファジーを阻害することで、心筋虚血・再灌流傷害を抑制することが示唆された

Electroacupuncture preconditioning attenuates myocardial ischemia-reperfusion injury by inhibiting mitophagy mediated by the mTORC1-ULK1-FUNDC1 pathway.
  • Yan Xiao
  • Wanying Chen
  • Zehao Zhong
  • Liang Ding
  • Hua Bai
  • Hao Chen
  • Hongru Zhang
  • Yihuang Gu
  • Shengfeng Lu
  • Biomed. Pharmacother..2020 Jul;127:110148. S0753-3322(20)30340-1. doi: 10.1016/j.biopha.2020.110148.Epub 2020-04-25.

好中球減少症の小児におけるポサコナゾール点滴静注液および経口懸濁液用粉末の薬物動態と安全性:非盲検,逐次用量漸増試験

Pharmacokinetics and safety of posaconazole intravenous solution and powder for oral suspension in children with neutropenia: an open-label, sequential dose-escalation trial.
  • Andreas H Groll
  • Hisham Abdel-Azim
  • Thomas Lehrnbecher
  • William J Steinbach
  • Amanda Paschke
  • Eric Mangin
  • Gregory A Winchell
  • Hetty Waskin
  • Christopher J Bruno
  • Int. J. Antimicrob. Agents.2020 Jul;:106084. S0924-8579(20)30254-5. doi: 10.1016/j.ijantimicag.2020.106084.Epub 2020-07-16.

精密免疫療法のためのスプリットT細胞エンゲージメント抗体のオンターゲット修復について

On-target restoration of a split T cell-engaging antibody for precision immunotherapy.
  • Agnes Banaszek
  • Thomas G P Bumm
  • Boris Nowotny
  • Maria Geis
  • Kim Jacob
  • Matthias Wölfl
  • Johannes Trebing
  • Kirstin Kucka
  • Dina Kouhestani
  • Tea Gogishvili
  • Bastian Krenz
  • Justina Lutz
  • Leo Rasche
  • Dirk Hönemann
  • Hannes Neuweiler
  • Julia C Heiby
  • Ralf C Bargou
  • Harald Wajant
  • Hermann Einsele
  • Gert Riethmüller
  • Gernot Stuhler
  • Nat Commun.2019 11;10(1):5387. 10.1038/s41467-019-13196-0. doi: 10.1038/s41467-019-13196-0.Epub 2019-11-26.

Prosopis farcta抽出物の高性能薄層クロマトグラフィーフィンガープリント、全フェノールおよび全フラボノイド含量、抗血小板凝集活性

High-performance thin-layer chromatography fingerprinting, total phenolic and total flavonoid contents and anti-platelet-aggregation activities of Prosopis farcta extracts.
  • Farzad Kobarfard
  • Seyed Abdulmajid Ayatollahi
  • Nafiseh Khosravi-Dehaghi
  • Mehrdad Faizi
  • Salimeh Amidi
  • Miquel Martorell
  • Muhammad Iqbal Choudhary
  • Hafiz Ansar Rasul Suleria
  • Javad Sharifi-Rad
  • Cell. Mol. Biol. (Noisy-le-grand).2020 Jun;66(4):8-14. Epub 2020-06-25.

患者別ガイドを用いたコンピュータガイド下の関節尖頭術」へのコメント。顎関節内側逸脱の治療のための新しいプロトコール」を発表しました

Comment on "Computer-Guided Arthrocentesis Using Patient-Specific Guides: A Novel Protocol for Treatment of Internal Derangement of the Temporomandibular Joint".
  • Salvatore Sembronio
  • Alessandro Tel
  • Massimo Robiony
  • J. Oral Maxillofac. Surg..2020 May;S0278-2391(20)30434-1. doi: 10.1016/j.joms.2020.04.028.Epub 2020-05-24.