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日本語AIでPubMedを検索

歯科医師情報サイトTOP / PubMed論文検索

日本語AIでPubMedを検索

PubMedの提供する医学論文データベースを日本語で検索できます。AI(Deep Learning)を活用した機械翻訳エンジンにより、精度高く日本語へ翻訳された論文をご参照いただけます。
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2020年07月 みんなが読んでいる論文

5-ブロモ-3,4-ジヒドロキシベンズアルデヒド（Polysiphonia morrowii由来）は、マウスのIgE/BSA刺激による肥満細胞活性化および受動的な皮膚アナフィラキシーを抑制する

5-Bromo-3,4-dihydroxybenzaldehyde from Polysiphonia morrowii attenuate IgE/BSA-stimulated mast cell activation and passive cutaneous anaphylaxis in mice.
  • Eui Jeong Han
  • Ilekuttige Priyan Shanura Fernando
  • Eun-A Kim
  • Junseong Kim
  • Kyungsook Jung
  • Seo-Young Kim
  • Seon-Heui Cha
  • Kil-Nam Kim
  • Soo-Jin Heo
  • Ginnae Ahn
  • Biochem. Pharmacol..2020 Jun;178:114087. S0006-2952(20)30323-3. doi: 10.1016/j.bcp.2020.114087.Epub 2020-06-10.

側方拡大咽頭形成術。閉塞性睡眠時無呼吸症候群の治療のための複合的な技術

Lateral-Expansion Pharyngoplasty: Combined Technique for the Treatment of Obstructive Sleep Apnea Syndrome.
  • José Antonio Pinto
  • Luciana Balester Mello de Godoy
  • Heloisa Dos Santos Sobreira Nunes
  • Kelly Elia Abdo
  • Gabriella Spinola Jahic
  • André Freitas Cavallini
  • Gabriel Santos Freitas
  • Davi Knoll Ribeiro
  • Caue Duarte
  • Int Arch Otorhinolaryngol.2020 Jan;24(1):e107-e111. 1033or. doi: 10.1055/s-0039-1695026.Epub 2019-11-04.

PPAR-β/δの活性化は、コラゲナーゼ誘発脳内出血マウスモデルにおいて、炎症とアポトーシスを抑制することで脳損傷を抑制する

Activation of PPAR-β/δ Attenuates Brain Injury by Suppressing Inflammation and Apoptosis in a Collagenase-Induced Intracerebral Hemorrhage Mouse Model.
  • Xiangming Tang
  • Kunning Yan
  • Yingge Wang
  • Yaping Wang
  • Hongmei Chen
  • Jiang Xu
  • Yaoyao Lu
  • Xiaohong Wang
  • Jingyan Liang
  • Xinjiang Zhang
  • Neurochem. Res..2020 Apr;45(4):837-850. 10.1007/s11064-020-02956-w. doi: 10.1007/s11064-020-02956-w.Epub 2020-01-14.

ニーマン・ピック病B型（酸スフィンゴミエリン酵素欠損症）成人を対象としたオリプダーゼアルファ（組換えヒト酸スフィンゴミエリン酵素）の第I相試験における新規の初用量副作用

Novel first-dose adverse drug reactions during a phase I trial of olipudase alfa (recombinant human acid sphingomyelinase) in adults with Niemann-Pick disease type B (acid sphingomyelinase deficiency).
  • Margaret M McGovern
  • Melissa P Wasserstein
  • Brian Kirmse
  • W Lane Duvall
  • Thomas Schiano
  • Beth L Thurberg
  • Susan Richards
  • Gerald F Cox
  • Genet. Med..2016 Jan;18(1):34-40. gim201524. doi: 10.1038/gim.2015.24.Epub 2015-04-02.

抗FIVペプチドC8の異なる電荷を持つ膜モデルへの結合。最初のドッキングから膜チューブレーションまで

Binding of the Anti-FIV Peptide C8 to Differently Charged Membrane Models: From First Docking to Membrane Tubulation.
  • Daniele Di Marino
  • Agostino Bruno
  • Manuela Grimaldi
  • Mario Scrima
  • Ilaria Stillitano
  • Giuseppina Amodio
  • Grazia Della Sala
  • Alice Romagnoli
  • Augusta De Santis
  • Ornella Moltedo
  • Paolo Remondelli
  • Giovanni Boccia
  • Gerardino D'Errico
  • Anna Maria D'Ursi
  • Vittorio Limongelli
  • Front Chem.2020;8:493. doi: 10.3389/fchem.2020.00493.Epub 2020-06-26.

1-エチル-3-メチルイミダゾリウムビス(トリフルオロメチルスルホニル)イミドイオン液体におけるEu(III)及びEu(II)配位の電気化学的及び分光学的研究

Electrochemical and Spectroscopic Study of Eu(III) and Eu(II) coordination in the 1-Ethyl-3-methylimidazolium Bis(trifluoromethylsulfonyl)imide Ionic Liquid.
  • David Bengio
  • Thomas Dumas
  • Sylvie Arpigny
  • Richard Husar
  • Eric Mendes
  • Pier-Lorenzo Solari
  • Michel L Schlegel
  • Daniel Schlegel
  • Stéphane Pellet-Rostaing
  • Philippe Moisy
  • Chemistry.2020 Jun;doi: 10.1002/chem.202001469.Epub 2020-06-12.

プロテアソームから免疫プロテアソームへの切り替えは、進行の速い免疫グロブリン腎症患者の循環細胞で増加し、CD46発現の欠損と関連している

The switch from proteasome to immunoproteasome is increased in circulating cells of patients with fast progressive immunoglobulin A nephropathy and associated with defective CD46 expression.
  • Licia Peruzzi
  • Rosanna Coppo
  • Enrico Cocchi
  • Elisa Loiacono
  • Massimilano Bergallo
  • Monica Bodria
  • Luca Vergano
  • Alexandra Krutova
  • Maria Luisa Russo
  • Alessandro Amore
  • Sigrid Lundberg
  • Dita Maixerova
  • Vladimir Tesar
  • Agnieszka Perkowska-Ptasińska
  • Magdalena Durlik
  • Dimitris Goumenos
  • Marios Papasotiriou
  • Kresimir Galesic
  • Luka Toric
  • Aikaterini Papagianni
  • Maria Stangou
  • Malgorzata Mizerska-Wasiak
  • Loreto Gesualdo
  • Eustacchio Montemurno
  • Luisa Benozzi
  • Stefano Cusinato
  • Tomasz Hryszko
  • Marian Klinger
  • Dorota Kamińska
  • Magdalena Krajewska
  • Nephrol. Dial. Transplant..2020 Jun;gfaa092. doi: 10.1093/ndt/gfaa092.Epub 2020-06-24.

FマウスおよびFマウスにおけるヒ素関連行動および生化学的変化のインビボ評価

In vivo evaluation of arsenic-associated behavioral and biochemical alterations in F and F mice.
  • Sheta Biswas
  • Hasan Ul Banna
  • Momotaj Jahan
  • Adiba Anjum
  • Abu Eabrahim Siddique
  • Apurba Roy
  • Farjana Nikkon
  • Kazi Abdus Salam
  • Azizul Haque
  • Seiichiro Himeno
  • Khaled Hossain
  • Zahangir Alam Saud
  • Chemosphere.2020 Apr;245:125619. S0045-6535(19)32859-0. doi: 10.1016/j.chemosphere.2019.125619.Epub 2019-12-10.

敗血症におけるアネキシンA3：公開されているトランスクリプトームデータの探索からの新たな展望

Annexin A3 in sepsis: novel perspectives from an exploration of public transcriptome data.
  • Mohammed Toufiq
  • Jessica Roelands
  • Mohamed Alfaki
  • Basirudeen Ahamed Kabeer
  • Marwa Saadaoui
  • Arun Prasath Lakshmanan
  • Dhinoth Kumar Bangarusamy
  • Selvasankar Murugesan
  • Davide Bedognetti
  • Wouter Hendrickx
  • Souhaila Al Khodor
  • Annalisa Terranegra
  • Darawan Rinchai
  • Damien Chaussabel
  • Mathieu Garand
  • Immunology.2020 Jul;doi: 10.1111/imm.13239.Epub 2020-07-18.

顔面CTを用いた外傷性脳損傷に対する視神経鞘厚さと視神経鞘径の予測性能の比較およびレトロスペクティブ評価を行った

Comparative and retrospective evaluation of the predictive performance of optic nerve sheath thickness and optic nerve sheath diameter for traumatic brain injury using facial computed tomography.
  • Woo Sung Sim
  • Sun Hwa Lee
  • Seong Jong Yun
  • Seokyong Ryu
  • Seung Woon Choi
  • Hye Jin Kim
  • Tae Kyung Kang
  • Sung Chan Oh
  • Suk Jin Cho
  • Clin Exp Emerg Med.2020 Jun;7(2):122-130. ceem.19.033. doi: 10.15441/ceem.19.033.Epub 2020-06-30.

Fasciola giganticaの排泄分泌産物（FgESPs）は、DNMT1とTET1が関与するメカニズムを介して、水牛樹状細胞の分化と免疫機能を調節する

Fasciola gigantica excretory-secretory products (FgESPs) modulate the differentiation and immune functions of buffalo dendritic cells through a mechanism involving DNMT1 and TET1.
  • Xuefang Mei
  • Wei Shi
  • Wenping Zhao
  • Honglin Luo
  • Yaoyao Zhang
  • Yurui Wang
  • Zhaoan Sheng
  • Dongying Wang
  • Xing-Quan Zhu
  • Weiyi Huang
  • Parasit Vectors.2020 Jul;13(1):355. 10.1186/s13071-020-04220-0. doi: 10.1186/s13071-020-04220-0.Epub 2020-07-17.

A549 肺癌細胞のアポトーシス活性を高めるナリンゲニンナノエマルジョンの製剤設計、統計的最適化、および in vitro 評価

Formulation Design, Statistical Optimization, and In Vitro Evaluation of a Naringenin Nanoemulsion to Enhance Apoptotic Activity in A549 Lung Cancer Cells.
  • Shadab Md
  • Nabil A Alhakamy
  • Hibah M Aldawsari
  • Mohammad Husain
  • Sabna Kotta
  • Samaa T Abdullah
  • Usama A Fahmy
  • Mohamed A Alfaleh
  • Hani Z Asfour
  • Pharmaceuticals (Basel).2020 Jul;13(7). E152. doi: 10.3390/ph13070152.Epub 2020-07-15.

インドのメトホルミンでコントロール不十分な2型糖尿病患者におけるエボグリプチン対シタグリプチンの追加療法としての有効性と安全性：24週間無作為化二重盲検非劣性試験、EVOLUTION INDIA試験

Efficacy and safety of evogliptin versus sitagliptin as an add-on therapy in Indian patients with type 2 diabetes mellitus inadequately controlled with metformin: A 24-week randomized, double-blind, non-inferiority, EVOLUTION INDIA study.
  • Ajay Kumar Ajmani
  • Aparna Agrawal
  • B L N Prasad
  • Indraneel Basu
  • Jayashree Shembalkar
  • Neeraj Manikanth
  • K A V Subrahmanyam
  • M Srinivasa
  • Manoj Chawla
  • Manoj Kumar Srivastava
  • Felix Jebasingh
  • Basavaprabhu Achappa
  • R P Agrawal
  • Rakesh K Pulichikkat
  • Ramdhan Meena
  • Shailaja Bhatia
  • Sandeep Kumar Gupta
  • Amol Dange
  • Ambrish Srivastava
  • Abhijit Trailokya
  • Vinayaka Shahavi
  • Sachin Shende
  • Diabetes Res. Clin. Pract..2019 Nov;157:107860. S0168-8227(19)30569-8. doi: 10.1016/j.diabres.2019.107860.Epub 2019-09-14.

不可逆性エレクトロポレーションとFOLFIRINOXを併用した電気化学療法は、膵腺癌のマウスモデルにおける生存率を改善する

Electrochemotherapy with Irreversible Electroporation and FOLFIRINOX Improves Survival in Murine Models of Pancreatic Adenocarcinoma.
  • Neal Bhutiani
  • Yan Li
  • Qianqian Zheng
  • Harshul Pandit
  • Xiaoju Shi
  • Yujia Chen
  • Youxi Yu
  • Zachary R Pulliam
  • Min Tan
  • Robert C G Martin
  • Ann. Surg. Oncol..2020 Jul;10.1245/s10434-020-08782-2. doi: 10.1245/s10434-020-08782-2.Epub 2020-07-17.

パエオニーの全グルコシド（TGP）は、シェーグレン症候群を誘発したマウスの便秘と腸の炎症を緩和する

Total glucosides of paeony (TGP) alleviates constipation and intestinal inflammation in mice induced by Sjögren's syndrome.
  • Ge Liu
  • Ziyu Wang
  • Xiang Li
  • Rui Liu
  • Binbin Li
  • Liangliang Huang
  • Yan Chen
  • Chongxi Zhang
  • Honghao Zhang
  • Yunman Li
  • Yongjian Chen
  • Hong Yin
  • Weirong Fang
  • J Ethnopharmacol.2020 Jun;260:113056. S0378-8741(20)31426-4. doi: 10.1016/j.jep.2020.113056.Epub 2020-06-07.

プロゲステロン、サイクリックAMP、子宮筋膜細胞における炎症による転写シグナルの相互作用：ヒトの分娩制御の意味合い

Interplay of transcriptional signaling by progesterone, cyclic AMP, and inflammation in myometrial cells: implications for the control of human parturition.
  • Zachary Stanfield
  • Peyvand Amini
  • Junye Wang
  • Lijuan Yi
  • Huiqing Tan
  • Mark R Chance
  • Mehmet Koyutürk
  • Sam Mesiano
  • Mol. Hum. Reprod..2019 07;25(7):408-422. 5520326. doi: 10.1093/molehr/gaz028.

冠動脈バイパスグラフト（CABG）手術を受けている糖尿病のない患者さんのストレス性高血糖症を予防するシタグリプチンの効能・効果

Sitagliptin for the prevention of stress hyperglycemia in patients without diabetes undergoing coronary artery bypass graft (CABG) surgery.
  • Saumeth Cardona
  • Katerina Tsegka
  • Francisco J Pasquel
  • Maya Fayfman
  • Limin Peng
  • Sol Jacobs
  • Priyathama Vellanki
  • Michael Halkos
  • Robert A Guyton
  • Vinod H Thourani
  • Rodolfo J Galindo
  • Guillermo Umpierrez
  • BMJ Open Diabetes Res Care.2019;7(1):e000703. bmjdrc-2019-000703. doi: 10.1136/bmjdrc-2019-000703.Epub 2019-09-03.

原発性アルドステロン症のサブタイプ診断、治療、合併症、転帰と今後の研究の方向性：欧州高血圧学会内分泌性高血圧ワーキンググループの立場表明とコンセンサス

Subtype diagnosis, treatment, complications and outcomes of primary aldosteronism and future direction of research: a position statement and consensus of the Working Group on Endocrine Hypertension of the European Society of Hypertension.
  • Paolo Mulatero
  • Leonardo A Sechi
  • Tracy Ann Williams
  • Jacques W M Lenders
  • Martin Reincke
  • Fumitoshi Satoh
  • Andrzej Januszewicz
  • Mitsuhide Naruse
  • Michael Doumas
  • Franco Veglio
  • Vin Cent Wu
  • Jiri Widimsky
  • J. Hypertens..2020 Jun;doi: 10.1097/HJH.0000000000002520.Epub 2020-06-25.

非弁膜症性心房細動および有意な弁膜症を有する心房細動患者が電気的除細動のために再診された場合の特徴と予後

Characteristics and Prognosis of Patients With Nonvalvular Atrial Fibrillation and Significant Valvular Heart Disease Referred for Electrical Cardioversion.
  • N Mai Vo
  • Melissa Leung
  • Phillippe J van Rosendael
  • Laurien Goedemans
  • Suzanne E van Wijngaarden
  • Edgard A Prihadi
  • Pieter van der Bijl
  • Nina Ajmone Marsan
  • Victoria Delgado
  • Jeroen J Bax
  • Am. J. Cardiol..2020 Aug;128:84-91. S0002-9149(20)30454-9. doi: 10.1016/j.amjcard.2020.04.035.Epub 2020-05-13.

小麦NHXアンチポーター遺伝子TaNHX2は、トランスジェニックアルファルファにおいて、細胞内カリウムの保持能力を増加させることで塩耐性を付与する

The wheat NHX antiporter gene TaNHX2 confers salt tolerance in transgenic alfalfa by increasing the retention capacity of intracellular potassium.
  • Yan-Min Zhang
  • Hong-Mei Zhang
  • Zi-Hui Liu
  • Hui-Cong Li
  • Xiu-Lin Guo
  • Guo-Liang Li
  • Plant Mol. Biol..2015 Feb;87(3):317-27. doi: 10.1007/s11103-014-0278-6.Epub 2014-12-31.

一次元配位高分子Fe(ebtz)2(C2H5CN)2(BF4)2の時空間的研究。綱引き-スピンクロスオーバー特性の調整のためのツールとしてのニトリルの再配向対結晶格子

Spatiotemporal studies of the one dimensional coordination polymer [Fe(ebtz)2(C2H5CN)2](BF4)2. Tug of war - nitrile reorientation versus crystal lattice as tool for tuning of spin crossover properties.
  • Robert Bronisz
  • Maria Książek
  • Marek Weselski
  • Marcin Kaźmierczak
  • Aleksandra Tołoczko
  • Miłosz Siczek
  • Piotr Durlak
  • Juliusz A Wolny
  • Volker Schünemann
  • Joachim Kusz
  • Chemistry.2020 Jul;doi: 10.1002/chem.202002460.Epub 2020-07-17.

高血圧高齢女性の健康増進のための新たなツールとしての血流制限付き運動：プリンリン作動性酵素の役割

Exercise with blood flow restriction as a new tool for health improvement in hypertensive elderly women: the role of purinergic enzymes.
  • Aline Mânica
  • Clodoaldo A De SÁ
  • Angélica Barili
  • Vanessa S Corralo
  • Beatriz S Bonadiman
  • Gabriela G Oliveira
  • Margarete D Bagatini
  • Andréia M Cardoso
  • J Sports Med Phys Fitness.2020 Jul;S0022-4707.20.10956-3. doi: 10.23736/S0022-4707.20.10956-3.Epub 2020-07-16.

カーボンナノチューブとフラーレンによって誘導されたマウスの肺炎の解決。マクロファージの分極の役割

Resolution of Pulmonary Inflammation Induced by Carbon Nanotubes and Fullerenes in Mice: Role of Macrophage Polarization.
  • Chol Seung Lim
  • Dale W Porter
  • Marlene S Orandle
  • Brett J Green
  • Mark A Barnes
  • Tara L Croston
  • Michael G Wolfarth
  • Lori A Battelli
  • Michael E Andrew
  • Donald H Beezhold
  • Paul D Siegel
  • Qiang Ma
  • Front Immunol.2020;11:1186. doi: 10.3389/fimmu.2020.01186.Epub 2020-06-12.

特発性アカラシア症患者における内視鏡的または外科的筋腫切開術

Endoscopic or Surgical Myotomy in Patients with Idiopathic Achalasia.
  • Yuki B Werner
  • Bengt Hakanson
  • Jan Martinek
  • Alessandro Repici
  • Burkhard H A von Rahden
  • Albert J Bredenoord
  • Raf Bisschops
  • Helmut Messmann
  • Marius C Vollberg
  • Tania Noder
  • Jan F Kersten
  • Oliver Mann
  • Jakob Izbicki
  • Alexander Pazdro
  • Uberto Fumagalli
  • Riccardo Rosati
  • Christoph-Thomas Germer
  • Marlies P Schijven
  • Alice Emmermann
  • Daniel von Renteln
  • Paul Fockens
  • Guy Boeckxstaens
  • Thomas Rösch
  • N. Engl. J. Med..2019 12;381(23):2219-2229. doi: 10.1056/NEJMoa1905380.

父性遺伝性突然変異とモザイク型父性一親性ディスミー11p高インスリン症の共存

Coexistence of paternally-inherited mutation and mosaic paternal uniparental disomy 11p hyperinsulinism.
  • Joanna Yuet-Ling Tung
  • Sophie Hon Yu Lai
  • Sandy Leung Kuen Au
  • Kit San Yeung
  • Anita Sik Yau Kan
  • Florence Loong
  • Diva D DeLeón
  • Jennifer M Kalish
  • Arupa Ganguly
  • Brian Hon Yin Chung
  • Kelvin Yuen Kwong Chan
  • Int J Pediatr Endocrinol.2020;2020:13. 83. doi: 10.1186/s13633-020-00083-5.Epub 2020-07-10.

Fynキナーゼ阻害は、トランスジェニックタウオパシーおよび外傷性タウオパシーにおいて、タンパク質の凝集を減少させ、シナプス密度を増加させ、記憶を改善する

Fyn kinase inhibition reduces protein aggregation, increases synapse density and improves memory in transgenic and traumatic Tauopathy.
  • Si Jie Tang
  • Arman Fesharaki-Zadeh
  • Hideyuki Takahashi
  • Sarah Helena Nies
  • Levi M Smith
  • Anin Luo
  • Annabel Chyung
  • Marius Chiasseu
  • Stephen M Strittmatter
  • Acta Neuropathol Commun.2020 Jul;8(1):96. 10.1186/s40478-020-00976-9. doi: 10.1186/s40478-020-00976-9.Epub 2020-07-01.

GPIの両側DBS後の小児脳の死後病理組織学：症例報告と文献のレビュー

Post-mortem histopathology of a pediatric brain after bilateral DBS of GPI for status dystonicus: case report and review of the literature.
  • Flavio Giordano
  • Chiara Caporalini
  • Simone Peraio
  • Lorenzo Mongardi
  • Anna Maria Buccoliero
  • Michele Alessandro Cavallo
  • Lorenzo Genitori
  • Matteo Lenge
  • Regina Mura
  • Federico Melani
  • Manuela L'Erario
  • Leonardo Lelli
  • Michele Pennica
  • Childs Nerv Syst.2020 Jul;10.1007/s00381-020-04761-w. doi: 10.1007/s00381-020-04761-w.Epub 2020-07-02.

非侵襲的な高速フラクショナルフローリザーブに対する平均血圧と左室質量の効果の定量化．

Quantification of Effects of Mean Blood Pressure and Left Ventricular Mass on Noninvasive Fast Fractional Flow Reserve.
  • Jun-Mei Zhang
  • Gaurav Chandola
  • Rusan Tan
  • Ping Chai
  • Lynette Ls Teo
  • Ris Low
  • John Carson Allen
  • Weimin Huang
  • Jiang Ming Fam
  • Chee Yang Chin
  • Aaron Sung Lung Wong
  • Adrian F Low
  • Ghassan S Kassab
  • Terrance Siang Jin Chua
  • Swee Yaw Tan
  • Soo Teik Lim
  • Liang Zhong
  • Am. J. Physiol. Heart Circ. Physiol..2020 Jul;doi: 10.1152/ajpheart.00135.2020.Epub 2020-07-17.

有機ナノ構造ヘテロ接合をベースにした10MHz半波整流器としての集積化分子ダイオード

Integrated molecular diode as 10 MHz half-wave rectifier based on an organic nanostructure heterojunction.
  • Tianming Li
  • Vineeth Kumar Bandari
  • Martin Hantusch
  • Jianhui Xin
  • Robert Kuhrt
  • Rachappa Ravishankar
  • Longqian Xu
  • Jidong Zhang
  • Martin Knupfer
  • Feng Zhu
  • Donghang Yan
  • Oliver G Schmidt
  • Nat Commun.2020 Jul;11(1):3592. 10.1038/s41467-020-17352-9. doi: 10.1038/s41467-020-17352-9.Epub 2020-07-17.

グラフェン上に欠陥の多いハニカム状のニッケルコバルト硫化物をマイクロ波を用いて高速合成し、超高速スーパーキャパシタを実現した

Defect-rich honeycomb-like nickel cobalt sulfides on graphene through rapid microwave-induced synthesis for ultrahigh rate supercapacitors.
  • Fenglin Zhao
  • Dong Xie
  • Wanxia Huang
  • Xinrui Song
  • Muhammad Aurang Zeb Gul Sial
  • Hongliang Wu
  • Fei Deng
  • Qi Zhang
  • Jizhao Zou
  • Xierong Zeng
  • J Colloid Interface Sci.2020 Jun;580:160-170. S0021-9797(20)30836-5. doi: 10.1016/j.jcis.2020.06.091.Epub 2020-06-25.

Gd-EOB-DTPA（Primovist/Eovist）およびGd-DOTA（Dotarem）-強化ダイナミックフェーズ肝臓MRIにおける呼吸運動のアーチファクト。二院間での分析

Respiratory motion artefacts in Gd-EOB-DTPA (Primovist/Eovist) and Gd-DOTA (Dotarem)-enhanced dynamic phase liver MRI after intensified and standard pre-scan patient preparation: A bi-institutional analysis.
  • Christian Wybranski
  • Florian Siedek
  • Robert Damm
  • Angelos Gazis
  • Ortrud Wenzel
  • Stefan Haneder
  • Thorsten Persigehl
  • Susanne Steinhauser
  • Maciej Pech
  • Frank Fischbach
  • Katharina Fischbach
  • PLoS ONE.2020;15(3):e0230024. PONE-D-19-32369. doi: 10.1371/journal.pone.0230024.Epub 2020-03-20.

耐久性、効率性、広い適用性を有する超疎水性ナノ構造表面をワンステップ、低コストで作成するために、イ貝にインスパイアされたグリーンな方法

One-step, low-cost, mussel-inspired green method to prepare superhydrophobic nanostructured surfaces having durability, efficiency, and wide applicability.
  • Jin Zhang
  • Jianguo Zhao
  • Wenshan Qu
  • Xinyu Li
  • Zhenxing Wang
  • J Colloid Interface Sci.2020 Jul;580:211-222. S0021-9797(20)30905-X. doi: 10.1016/j.jcis.2020.07.027.Epub 2020-07-13.

脊椎手術後の症候性血腫の発生率と臨床的特徴。45 例の患者を対象とした多施設共同研究

Incidence and Clinical Features of Postoperative Symptomatic Hematoma after Spine Surgery: A Multicenter Study of 45 Patients.
  • Soichiro Masuda
  • Shunsuke Fujibayashi
  • Mitsuru Takemoto
  • Youngwoo Kim
  • Bungo Otsuki
  • Masato Ota
  • Tsunemitsu Soeda
  • Kei Watanabe
  • Takeshi Sakamoto
  • Naoya Tsubouchi
  • Shuichi Matsuda
  • Spine Surg Relat Res.2020;4(2):130-134. doi: 10.22603/ssrr.2019-0080.Epub 2019-11-01.

ジンセノサイドRg1は、ファルネソイドX受容体を活性化し、トランスポーターや代謝酵素を調節することにより、ラットのANIT誘発性肝内胆汁症を緩和します

Ginsenoside Rg1 alleviates ANIT-induced intrahepatic cholestasis in rats via activating farnesoid X receptor and regulating transporters and metabolic enzymes.
  • Qing Xiao
  • Shujun Zhang
  • Huina Ren
  • Ruoyang Du
  • Jiajun Li
  • Jinqiu Zhao
  • Yue Gao
  • Yali Zhu
  • Wenxiang Huang
  • Chem. Biol. Interact..2020 Jun;324:109062. S0009-2797(19)31928-3. doi: 10.1016/j.cbi.2020.109062.Epub 2020-03-18.

多機能マグネタイトナノ粒子のドラッグデリバリーへの応用。本研究では、このような多機能マグネタイトナノ粒子の調製、特性評価、抗菌性、薬物放出速度などの研究を行っている

Multifunctional Magnetite Nanoparticlesfor Drug Delivery: Preparation, Characterisation, Antibacterial Properties and Drug Release Kinetics.
  • Mostafa Mabrouk
  • Rasha M Abd El-Wahab
  • Hanan H Beherei
  • Mohamed M Selim
  • Diganta B Das
  • Int J Pharm.2020 Jul;:119658. S0378-5173(20)30642-6. doi: 10.1016/j.ijpharm.2020.119658.Epub 2020-07-16.

屋内の粉塵中の汚染物質分析のための液体クロマトグラフィーイオンモビリティー高分解能質量分析装置。識別と予測能力

Liquid chromatography-ion mobility-high resolution mass spectrometry for analysis of pollutants in indoor dust: Identification and predictive capabilities.
  • Lauren Mullin
  • Karl Jobst
  • Robert A DiLorenzo
  • Robert Plumb
  • Eric J Reiner
  • Leo W Y Yeung
  • Ingrid Ericson Jogsten
  • Anal. Chim. Acta.2020 Aug;1125:29-40. S0003-2670(20)30604-8. doi: 10.1016/j.aca.2020.05.052.Epub 2020-05-23.

二重変調されたフォトニック結晶により、高出力で高品質な二次元ビーム走査レーザーを実現しています

Dually modulated photonic crystals enabling high-power high-beam-quality two-dimensional beam scanning lasers.
  • Ryoichi Sakata
  • Kenji Ishizaki
  • Menaka De Zoysa
  • Shin Fukuhara
  • Takuya Inoue
  • Yoshinori Tanaka
  • Kintaro Iwata
  • Ranko Hatsuda
  • Masahiro Yoshida
  • John Gelleta
  • Susumu Noda
  • Nat Commun.2020 Jul;11(1):3487. 10.1038/s41467-020-17092-w. doi: 10.1038/s41467-020-17092-w.Epub 2020-07-17.

Rad51阻害剤DIDSとヒトおよびウシ血清アルバミンとの相互作用。光学分光法と等温熱量測定法によるアプローチ

Interactions of the Rad51 inhibitor DIDS with human and bovine serum albumins: Optical spectroscopy and isothermal calorimetry approaches.
  • Denis Velic
  • Cathy Charlier
  • Milena Popova
  • Titouan Jaunet-Lahary
  • Zakaria Bouchouireb
  • Sébastien Henry
  • Pierre Weigel
  • Jean-Yves Masson
  • Adèle Laurent
  • Igor Nabiev
  • Fabrice Fleury
  • Biochimie.2019 Dec;167:187-197. S0300-9084(19)30274-3. doi: 10.1016/j.biochi.2019.09.016.Epub 2019-09-25.

スペインにおける外科的大動脈弁置換術の利用率と院内アウトカムの全国的傾向、2001年～2015年

National Trends in Utilization and In-Hospital Outcomes of Surgical Aortic Valve Replacements in Spain, 2001-2015.
  • Rodrigo Jiménez-García
  • Napoleón Perez-Farinos
  • Javier de Miguel-Díez
  • Valentín Hernández-Barrera
  • Manuel Méndez-Bailón
  • Isabel Jimenez-Trujillo
  • José M de Miguel-Yanes
  • Ana López-de-Andrés
  • Braz J Cardiovasc Surg.2020 02;35(1):65-74. doi: 10.21470/1678-9741-2019-0181.Epub 2020-02-01.

自閉症スペクトラム障害と知的障害を持つ子どもの機能と症状を改善するためのビデオモデリングを用いた親のトレーニングの有効性を検証するための無作為化臨床パイロット試験

A randomised clinical pilot trial to test the effectiveness of parent training with video modelling to improve functioning and symptoms in children with autism spectrum disorders and intellectual disability.
  • D Bordini
  • C S Paula
  • G R Cunha
  • S C Caetano
  • L F Bagaiolo
  • T C Ribeiro
  • M C C Martone
  • J Portolese
  • A C Moya
  • D Brunoni
  • C Bosa
  • H Brentani
  • H Cogo-Moreira
  • J de Jesus Mari
  • J Intellect Disabil Res.2020 Aug;64(8):629-643. doi: 10.1111/jir.12759.Epub 2020-06-30.

健康な内皮コロニー形成細胞における内皮の特性；血管疾患のための頑健で有効な生体外モデルを生成する

Endothelial characteristics in healthy endothelial colony forming cells; generating a robust and valid ex vivo model for vascular disease.
  • Suzan de Boer
  • Mackenzie Bowman
  • Colleen Notley
  • Aomei Mo
  • Patricia Lima
  • Annika de Jong
  • Richard Dirven
  • Ester Weijers
  • David Lillicrap
  • Paula James
  • Jeroen Eikenboom
  • J. Thromb. Haemost..2020 Jul;doi: 10.1111/jth.14998.Epub 2020-07-12.

腸内細菌の家族は、メキシコの農村部の学齢児の体組成とメタボリックリスクマーカーと関連付けられています

Gut Bacterial Families Are Associated with Body Composition and Metabolic Risk Markers in School-Aged Children in Rural Mexico.
  • Tania Aguilar
  • Gerardo M Nava
  • Andrea M Olvera-Ramírez
  • Dolores Ronquillo
  • Mariela Camacho
  • Gerardo A Zavala
  • María C Caamaño
  • Karina Acevedo-Whitehouse
  • Jorge L Rosado
  • Olga P García
  • Child Obes.2020 Jul;16(5):358-366. doi: 10.1089/chi.2019.0312.Epub 2020-05-19.

マレーシア人口におけるβ-タラセミアの遺伝子型-フェノタイプ相関.効果的な遺伝カウンセリングに向けて

Genotype-Phenotype Correlation of β-Thalassemia in Malaysian Population: Toward Effective Genetic Counseling.
  • Uday Y H Abdullah
  • Hishamshah M Ibrahim
  • Noraesah Binti Mahmud
  • Mohamad Zaki Salleh
  • Lay Kek Teh
  • Mohd Nur Fakhruzzaman Bin Noorizhab
  • Bin Alwi Zilfalil
  • Haitham Muhammed Jassim
  • Prapin Wilairat
  • Suthat Fucharoen
  • Hemoglobin.2020 Jun;:1-6. doi: 10.1080/03630269.2020.1781652.Epub 2020-06-26.

ブドウ種子プロアントシアニジン抽出物は、酸化ストレスを抑制し、AKTとERK活性を保持することにより、ストレプトゾトシン誘発性の認知およびシナプス可塑性障害を改善します

Grape Seed Proanthocyanidin Extract Ameliorates Streptozotocin-induced Cognitive and Synaptic Plasticity Deficits by Inhibiting Oxidative Stress and Preserving AKT and ERK Activities.
  • Wei-Li Gao
  • Xiang-Hua Li
  • Xin-Peng Dun
  • Xiao-Kuan Jing
  • Ke Yang
  • Yan-Kun Li
  • Curr Med Sci.2020 Jun;40(3):434-443. 10.1007/s11596-020-2197-x. doi: 10.1007/s11596-020-2197-x.Epub 2020-07-17.

照射下鼻全摘術を受けた患者に対して、頬骨インプラント1本をナビゲーション外科的に埋入して補綴再建を行った。臨床報告

Prosthetic reconstruction of a patient with an irradiated total rhinectomy with navigated surgical placement of a single zygomatic implant: A clinical report.
  • Theodore V Tso
  • Denny Chao
  • Jeffrey Tanner
  • Earl G Freymiller
  • Jay Jayanetti
  • J Prosthet Dent.2020 Apr;S0022-3913(20)30161-X. doi: 10.1016/j.prosdent.2020.02.024.Epub 2020-04-25.

イランから入院したCOVID-19患者にみられた口腔咽頭カンジダ症。種の同定と抗真菌感受性のパターン

Oropharyngeal candidiasis in hospitalized COVID-19 Patients from Iran: Species identification and antifungal susceptibility pattern.
  • Mohammadreza Salehi
  • Kazem Ahmadikia
  • Shahram Mahmoudi
  • Saeed Kalantari
  • Saeidreza Jamalimoghadam Siahkali
  • Alireza Izadi
  • Mohammad Kord
  • Seyed Ali Dehghan Manshadi
  • Arash Seifi
  • Fereshteh Ghiasvand
  • Nasim Khajavirad
  • Saeedeh Ebrahimi
  • Amirhossein Koohfar
  • Teun Boekhout
  • Sadegh Khodavaisy
  • Mycoses.2020 Jul;doi: 10.1111/myc.13137.Epub 2020-07-01.

コルチコトロピン放出因子受容体のホルモン認識と活性化の分子基盤

Molecular Basis for Hormone Recognition and Activation of Corticotropin-Releasing Factor Receptors.
  • Shanshan Ma
  • Qingya Shen
  • Li-Hua Zhao
  • Chunyou Mao
  • X Edward Zhou
  • Dan-Dan Shen
  • Parker W de Waal
  • Peng Bi
  • Chuntao Li
  • Yi Jiang
  • Ming-Wei Wang
  • Patrick M Sexton
  • Denise Wootten
  • Karsten Melcher
  • Yan Zhang
  • H Eric Xu
  • Mol. Cell.2020 02;77(3):669-680.e4. S1097-2765(20)30013-7. doi: 10.1016/j.molcel.2020.01.013.Epub 2020-01-30.

土壌蓄積係数とDTPA抽出を用いた汚染土壌におけるCu, Cd, Pb, Znのバイオアベイラビリティーに対するミミズ活性の評価

Assessment of earthworm activity on Cu, Cd, Pb and Zn bioavailability in contaminated soils using biota to soil accumulation factor and DTPA extraction.
  • Ling Xiao
  • Ming-Hui Li
  • Jun Dai
  • Mikael Motelica-Heino
  • Xu-Fei Chen
  • Jia-Long Wu
  • Lanfeng Zhao
  • Kexue Liu
  • Chi Zhang
  • Ecotoxicol. Environ. Saf..2020 Jun;195:110513. S0147-6513(20)30352-3. doi: 10.1016/j.ecoenv.2020.110513.Epub 2020-03-23.

ニホンウズラ（Coturnix japonica）におけるアドレノメデュリンの食欲不振作用には、視床下部の弧状核におけるプロピオメラノコルチンとコカインおよびアンフェタミン調節されたトランスクリプトmRNAの増加が関与しています

The anorexigenic effect of adrenomedullin in Japanese quail (Coturnix japonica) involves increased proopiomelanocortin and cocaine- and amphetamine-regulated transcript mRNAs in the arcuate nucleus of the hypothalamus.
  • J Wang
  • A Webster
  • W Sims
  • E R Gilbert
  • M A Cline
  • Domest. Anim. Endocrinol..2020 Mar;74:106465. S0739-7240(20)30032-1. doi: 10.1016/j.domaniend.2020.106465.Epub 2020-03-02.

GNAQ および GNA11 変異型非ぶどう膜黒色腫：皮膚黒色腫とぶどう膜黒色腫の両方とは異なるサブタイプ

GNAQ and GNA11 mutant nonuveal melanoma: a subtype distinct from both cutaneous and uveal melanoma.
  • E Livingstone
  • A Zaremba
  • S Horn
  • S Ugurel
  • B Casalini
  • M Schlaak
  • J C Hassel
  • R Herbst
  • J S Utikal
  • B Weide
  • R Gutzmer
  • F Meier
  • C Koelsche
  • E Hadaschik
  • A Sucker
  • H Reis
  • S Merkelbach-Bruse
  • M Siewert
  • F Sahm
  • A von Deimling
  • I Cosgarea
  • L Zimmer
  • D Schadendorf
  • B Schilling
  • K G Griewank
  • Br. J. Dermatol..2020 Feb;doi: 10.1111/bjd.18947.Epub 2020-02-16.

フタル酸ジ(2-エチルヘキシル)は、視床下部-下垂体-卵巣軸の障害を介してウズラの卵巣の発達異常を誘発した

Di-(2-ethylhexyl) phthalate induced developmental abnormalities of the ovary in quail (Coturnix japonica) via disruption of the hypothalamic-pituitary-ovarian axis.
  • Xue-Nan Li
  • Hui-Xin Li
  • Tian-Ning Yang
  • Xiao-Wei Li
  • Yue-Qiang Huang
  • Shi-Yong Zhu
  • Jin-Long Li
  • Sci. Total Environ..2020 Jun;741:140293. S0048-9697(20)33814-6. doi: 10.1016/j.scitotenv.2020.140293.Epub 2020-06-18.

ロイコトリエン受容体拮抗薬は、ADAMsを阻害し、MICAの脱落を抑制することで、HCCの治療効果を高める

Leukotriene receptor antagonists enhance HCC treatment efficacy by inhibiting ADAMs and suppressing MICA shedding.
  • Jun Arai
  • Kaku Goto
  • Yumi Otoyama
  • Yoko Nakajima
  • Ikuya Sugiura
  • Atsushi Kajiwara
  • Masayuki Tojo
  • Yuki Ichikawa
  • Shojiro Uozumi
  • Yuu Shimozuma
  • Manabu Uchikoshi
  • Masashi Sakaki
  • Hisako Nozawa
  • Ryo Nakagawa
  • Ryosuke Muroyama
  • Naoya Kato
  • Hitoshi Yoshida
  • Cancer Immunol. Immunother..2020 Jul;10.1007/s00262-020-02660-2. doi: 10.1007/s00262-020-02660-2.Epub 2020-07-18.

ポドサイト特異的な尿細管硬化複合体2の欠失は、局所的な細分化糸球体硬化症と進行性腎不全を促進する

Podocyte-specific deletion of tubular sclerosis complex 2 promotes focal segmental glomerulosclerosis and progressive renal failure.
  • Wakiko Iwata
  • Hiroyuki Unoki-Kubota
  • Hideki Kato
  • Akira Shimizu
  • Michihiro Matsumoto
  • Toshiyuki Imasawa
  • Arisa Igarashi
  • Kenji Matsumoto
  • Tetsuo Noda
  • Yasuo Terauchi
  • Masaomi Nangaku
  • Masato Kasuga
  • Yasushi Kaburagi
  • PLoS ONE.2020;15(3):e0229397. PONE-D-19-22136. doi: 10.1371/journal.pone.0229397.Epub 2020-03-19.

キトサン-PLGA ナノ粒子の特性を調節して、鼻から脳へのルートを意図した神経膠芽腫治療のための共同デリバリープラットフォームを設計する

Modulating chitosan-PLGA nanoparticle properties to design a co-delivery platform for glioblastoma therapy intended for nose-to-brain route.
  • Natália N Ferreira
  • Sara Granja
  • Fernanda I Boni
  • Fabíola G Prezotti
  • Leonardo M B Ferreira
  • Beatriz S F Cury
  • Rui M Reis
  • Fátima Baltazar
  • Maria Palmira D Gremião
  • Drug Deliv Transl Res.2020 Jul;10.1007/s13346-020-00824-2. doi: 10.1007/s13346-020-00824-2.Epub 2020-07-18.

分解性ホモ対マルチブロックコポリマーとその（ミクロ）構造を確立された生体材料と比較したin vivo生体適合性の研究

In vivo biocompatibility study of degradable homo- versus multiblock copolymers and their (micro)structure compared to an established biomaterial.
  • Tobias Haase
  • Robert Klopfleisch
  • Annalena Krost
  • Tilman Sauter
  • Karl Kratz
  • Jan Peter
  • Friedrich Jung
  • Andreas Lendlein
  • Dietlind Zohlnhöfer
  • Constantin Rüder
  • Clin. Hemorheol. Microcirc..2020 Jan;CH190748. doi: 10.3233/CH-190748.Epub 2020-01-04.

酸性スフィンゴミエリン酵素欠乏症における生化学的および画像化パラメータ。バイオマーカーとしての潜在的有用性

Biochemical and imaging parameters in acid sphingomyelinase deficiency: Potential utility as biomarkers.
  • Eline C B Eskes
  • Barbara Sjouke
  • Frédéric M Vaz
  • Susan M I Goorden
  • André B P van Kuilenburg
  • Johannes M F G Aerts
  • Carla E M Hollak
  • Mol. Genet. Metab..2020 05;130(1):16-26. S1096-7192(20)30052-4. doi: 10.1016/j.ymgme.2020.02.002.Epub 2020-02-12.

胃癌のイメージングおよび血管新生治療のためのTGM2を標的とした新規二重機能プローブとしてGX1ダイマーを再標識しました

Re-labeled GX1 dimer as a novel dual-functional probe targeting TGM2 for imaging and antiangiogenic therapy of gastric cancer.
  • Jipeng Yin
  • Bo Xin
  • Xiaoli Hui
  • Na Chai
  • Liping Yao
  • Hao Hu
  • Bing Xu
  • Wenhui Ma
  • Mingru Zhang
  • Jing Wang
  • Yongzhan Nie
  • Guangqing Zhou
  • Guanliang Wang
  • Liusheng Chen
  • Hongbing Lu
  • Kaichun Wu
  • Eur J Pharm Biopharm.2020 Jul;S0939-6411(20)30218-6. doi: 10.1016/j.ejpb.2020.07.015.Epub 2020-07-16.

MANα1-2MAN装飾リポソームは、BoHV-1に対するDNAワクチンで誘導される免疫原性を向上させる

MANα1-2MAN decorated liposomes enhance the immunogenicity induced by a DNA vaccine against BoHV-1.
  • Claudia Alejandra Kornuta
  • Juan Esteban Bidart
  • Ivana Soria
  • Mariela Gammella
  • Valeria Quattrocchi
  • Juan Sebastián Pappalardo
  • Stefano Salmaso
  • Vladimir Petrovich Torchilin
  • Felipe Cheuquepán Valenzuela
  • Yanina Hecker
  • Dadin Prando Moore
  • Patricia Inés Zamorano
  • Cecilia Ana Langellotti
  • Transbound Emerg Dis.2020 Jul;doi: 10.1111/tbed.13718.Epub 2020-07-09.

品質を高く保つ：マラリア迅速診断検査の品質管理におけるロット検査の利点

Keep the quality high: the benefits of lot testing for the quality control of malaria rapid diagnostic tests.
  • Sandra Incardona
  • David Bell
  • Ana Campillo
  • Jane Cunningham
  • Frederic Ariey
  • Thierry Fandeur
  • Jennifer Luchavez
  • Christian Anthony Luna
  • Didier Ménard
  • Sina Nhem
  • Johanna Beulah Sornillo
  • Benoit Witkowski
  • Zachary Katz
  • Sabine Dittrich
  • Xavier C Ding
  • Malar. J..2020 Jul;19(1):247. 10.1186/s12936-020-03324-3. doi: 10.1186/s12936-020-03324-3.Epub 2020-07-13.

新規ナトリウム利尿ペプチド受容体/グアニルシクラーゼA選択的アゴニストは、ヒト糸球体黄体細胞株におけるアンジオテンシンIIおよびフォルスコリン誘発アルドステロン合成を阻害する

Novel natriuretic peptide receptor/guanylyl cyclase A-selective agonist inhibits angiotensin II- and forskolin-evoked aldosterone synthesis in a human zona glomerulosa cell line.
  • L J Olson
  • D G Lowe
  • J G Drewett
  • Mol. Pharmacol..1996 Aug;50(2):430-5.

植物ホルモンタンパク質ネットワークによる広範なシグナル統合

Extensive signal integration by the phytohormone protein network.
  • Melina Altmann
  • Stefan Altmann
  • Patricia A Rodriguez
  • Benjamin Weller
  • Lena Elorduy Vergara
  • Julius Palme
  • Nora Marín-de la Rosa
  • Mayra Sauer
  • Marion Wenig
  • José Antonio Villaécija-Aguilar
  • Jennifer Sales
  • Chung-Wen Lin
  • Ramakrishnan Pandiarajan
  • Veronika Young
  • Alexandra Strobel
  • Lisa Gross
  • Samy Carbonnel
  • Karl G Kugler
  • Antoni Garcia-Molina
  • George W Bassel
  • Claudia Falter
  • Klaus F X Mayer
  • Caroline Gutjahr
  • A Corina Vlot
  • Erwin Grill
  • Pascal Falter-Braun
  • Nature.2020 07;583(7815):271-276. 10.1038/s41586-020-2460-0. doi: 10.1038/s41586-020-2460-0.Epub 2020-07-01.

マクロファージ遊走阻害因子の阻害は、急性膵炎の妊娠ラットにおける甲状腺機能障害を予防する

Inhibition of macrophage migration inhibitory factor prevents thyroid dysfunction in pregnant rats with acute pancreatitis.
  • Ying Chen
  • Chen-Yang Wang
  • Liang Zhao
  • Yu-Pu Hong
  • Xiao-Yi Zhang
  • Fang-Chao Mei
  • Yu Zhou
  • Wen-Yi Guo
  • Qiao Shi
  • Kai-Liang Zhao
  • Chen Chen
  • Jia Yu
  • Wei-Xing Wang
  • Int. Immunopharmacol..2020 Jul;87:106771. S1567-5769(19)33038-3. doi: 10.1016/j.intimp.2020.106771.Epub 2020-07-16.

ポリダチンによる SIRT1 活性化は、実験的糖尿病性神経障害における酸化的損傷を緩和し、ミトコンドリアの生合成を促進する

SIRT1 Activation by Polydatin Alleviates Oxidative Damage and Elevates Mitochondrial Biogenesis in Experimental Diabetic Neuropathy.
  • Preethi Bheereddy
  • Veera Ganesh Yerra
  • Anil Kumar Kalvala
  • Bhoomika Sherkhane
  • Ashutosh Kumar
  • Cell. Mol. Neurobiol..2020 Jul;10.1007/s10571-020-00923-1. doi: 10.1007/s10571-020-00923-1.Epub 2020-07-18.

水銀をナノモルレベルで選択的に検出・定量するためのAg-セルロースナノコンポジットの調製と光触媒性能の評価

Preparation of Ag-cellulose nanocomposite for the selective detection and quantification of mercury at nanomolar level and the evaluation of its photocatalytic performance.
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  • Asad Syed
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ラットの前頭前野前庭皮質におけるFos発現ニューロンアンサンブルはコカイン探索をコードしているが、ラットでは食物探索をコードしていない

Fos-expressing neuronal ensemble in rat ventromedial prefrontal cortex encodes cocaine seeking but not food seeking in rats.
  • Louisa Kane
  • Marco Venniro
  • Richard Quintana-Feliciano
  • Rajtarun Madangopal
  • F Javier Rubio
  • Jennifer M Bossert
  • Daniele Caprioli
  • Yavin Shaham
  • Bruce T Hope
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  • Addict Biol.2020 Jul;:e12943. doi: 10.1111/adb.12943.Epub 2020-07-19.

腎カルシウムおよびリン酸塩処理におけるアンドロゲンの作用。ビスフォスフォネート治療と低カルシウム食の効果

Androgen action on renal calcium and phosphate handling: Effects of bisphosphonate treatment and low calcium diet.
  • Rougin Khalil
  • Ioannis Simitsidellis
  • Na Ri Kim
  • Ferran Jardi
  • Dieter Schollaert
  • Ludo Deboel
  • Philippa Saunders
  • Geert Carmeliet
  • Frank Claessens
  • Dirk Vanderschueren
  • Brigitte Decallonne
  • Mol. Cell. Endocrinol..2020 Jun;514:110891. S0303-7207(20)30191-X. doi: 10.1016/j.mce.2020.110891.Epub 2020-06-10.

大気汚染と気候が都市の樹木の成長に果たす役割

The role of air pollution and climate on the growth of urban trees.
  • Giuliano Maselli Locosselli
  • Evelyn Pereira de Camargo
  • Tiana Carla Lopes Moreira
  • Enzo Todesco
  • Maria de Fátima Andrade
  • Carmen Diva Saldiva de André
  • Paulo Afonso de André
  • Julio M Singer
  • Luciana Schwandner Ferreira
  • Paulo Hilário Nascimento Saldiva
  • Marcos Silveira Buckeridge
  • Sci. Total Environ..2019 May;666:652-661. S0048-9697(19)30789-2. doi: 10.1016/j.scitotenv.2019.02.291.Epub 2019-02-19.

エンロフロキサシン投与前後のヤギ持続性乳房炎から分離された黄色ブドウ球菌のプロファイル

Profiles of Staphyloccocus aureus isolated from goat persistent mastitis before and after treatment with enrofloxacin.
  • Magna Coroa Lima
  • Mariana de Barros
  • Thalita Moreira Scatamburlo
  • Richard Costa Polveiro
  • Laís Karolyne de Castro
  • Samuel Henrique Sales Guimarães
  • Sanely Lourenço da Costa
  • Mateus Matiuzzi da Costa
  • Maria Aparecida Scatamburlo Moreira
  • BMC Microbiol..2020 May;20(1):127. 10.1186/s12866-020-01793-9. doi: 10.1186/s12866-020-01793-9.Epub 2020-05-24.

炎症性腸疾患患者における腸外症状。ENEIDA登録に基づく研究

Extraintestinal Manifestations in Patients with Inflammatory Bowel Disease: Study Based on the ENEIDA Registry.
  • Alicia Algaba
  • Iván Guerra
  • Elena Ricart
  • Eva Iglesias
  • Miriam Mañosa
  • Javier P Gisbert
  • Jordi Guardiola
  • Miguel Mínguez
  • Beatriz Castro
  • Ruth de Francisco
  • Pilar Nos
  • Federico Bertoletti
  • Francisco Mesonero
  • Jesús Barrio
  • María Dolores Martín-Arranz
  • Xavier Calvet
  • Santiago García-López
  • Beatriz Sicilia
  • Gillermo Alcaín
  • María Esteve
  • Lucía Márquez
  • Marta Piqueras
  • Laura Jiménez
  • José L Perez-Calle
  • Luis Bujanda
  • Mariana García-Sepulcre
  • Alejandra Fernández
  • Irene Moraleja
  • Rufo Humberto Lorente
  • Orlando García-Bosch
  • Ana Lambán
  • Isabel Blázquez
  • Esther Rodríguez
  • José M Huguet
  • Alfredo J Lucendo
  • Pedro Almela
  • David Busquets
  • Patricia Ramírez de la Piscina
  • Marcela Pérez
  • Eugeni Domenech
  • Fernando Bermejo
  • Dig. Dis. Sci..2020 Jul;10.1007/s10620-020-06424-x. doi: 10.1007/s10620-020-06424-x.Epub 2020-07-15.

顎関節人工関節の同心1本針穿刺術と従来の2本針穿刺術の比較研究とコルチコステロイド注射を併用した顎関節人工関節の研究

A Comparative Study Between Concentric Single-Needle Puncture Technique and Conventional 2-Needle Technique for Temporomandibular Joint Arthrocentesis Plus Corticosteroid Injections.
  • Amit Kumar
  • Amit Gupta
  • Rajarshi Ghosh
  • Rajeev Pandey
  • Sanjeev Kumar
  • Craniomaxillofac Trauma Reconstr.2020 Jun;13(2):99-104. 10.1177_1943387520911826. doi: 10.1177/1943387520911826.Epub 2020-03-17.

中国の地域保健センターにおけるスクリーニングによって明らかになった心房細動の検出率と治療ギャップ（AF-CATCH）。プロスペクティブな多施設共同研究

Detection rate and treatment gap for atrial fibrillation identified through screening in community health centers in China (AF-CATCH): A prospective multicenter study.
  • Yi Chen
  • Qi-Fang Huang
  • Chang-Sheng Sheng
  • Wei Zhang
  • Shuai Shao
  • Dian Wang
  • Yi-Bang Cheng
  • Ying Wang
  • Qian-Hui Guo
  • Dong-Yan Zhang
  • Yan Li
  • Nicole Lowres
  • Ben Freedman
  • Ji-Guang Wang
  • PLoS Med..2020 Jul;17(7):e1003146. PMEDICINE-D-19-04467. doi: 10.1371/journal.pmed.1003146.Epub 2020-07-16.

酸素によるヘモグロビンS繊維形成のアロステリック制御と鎌状赤血球病の病態との関係

Allosteric control of hemoglobin S fiber formation by oxygen and its relation to the pathophysiology of sickle cell disease.
  • Eric R Henry
  • Troy Cellmer
  • Emily B Dunkelberger
  • Belhu Metaferia
  • James Hofrichter
  • Quan Li
  • David Ostrowski
  • Rodolfo Ghirlando
  • John M Louis
  • Stéphane Moutereau
  • Frédéric Galactéros
  • Swee Lay Thein
  • Pablo Bartolucci
  • William A Eaton
  • Proc. Natl. Acad. Sci. U.S.A..2020 Jun;117(26):15018-15027. 1922004117. doi: 10.1073/pnas.1922004117.Epub 2020-06-11.

一過性中大脳動脈閉塞ラットモデルにおけるフルオキセチンのHIF-1α-Netrin/VEGFカスケード、血管新生および神経保護への影響

Effect of fluoxetine on HIF-1α- Netrin/VEGF cascade, angiogenesis and neuroprotection in a rat model of transient middle cerebral artery occlusion.
  • Qimin Hu
  • Lan Liu
  • Li Zhou
  • Haiyan Lu
  • Jiayi Wang
  • Xiangyan Chen
  • Qiaoshu Wang
  • Exp. Neurol..2020 Jul;329:113312. S0014-4886(20)30143-6. doi: 10.1016/j.expneurol.2020.113312.Epub 2020-04-12.

拡張スペクトラムβ-ラクタマーゼ(ESBL)/カルバペナマーゼ産生グラム陰性菌のプランクトン細胞およびバイオフィルム細胞に対する精油のin vitro活性

In Vitro Activity of Essential Oils Against Planktonic and Biofilm Cells of Extended-Spectrum β-Lactamase (ESBL)/Carbapenamase-Producing Gram-Negative Bacteria Involved in Human Nosocomial Infections.
  • Ramona Iseppi
  • Alessandro Di Cerbo
  • Piero Aloisi
  • Mattia Manelli
  • Veronica Pellesi
  • Cinzia Provenzano
  • Stefania Camellini
  • Patrizia Messi
  • Carla Sabia
  • Antibiotics (Basel).2020 May;9(5). E272. doi: 10.3390/antibiotics9050272.Epub 2020-05-25.

片側鼠径ヘルニア修復予定患者における対側鼡径部管理のための手術戦略。国際的なWebベースのSurveymonkeyアンケート。鼠径ヘルニア修復中の対側鼡径部管理の戦略

Surgical Strategy for Contralateral Groin Management in Patients Scheduled for Unilateral Inguinal Hernia Repair: An International Web-Based Surveymonkey Questionnaire: Strategy for Contralateral Groin Management during Inguinal Hernia Repair.
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  • A de Beaux
  • A Montgomery
  • J Macario Faylona
  • A Carbonell
  • T Bisgaard
  • Scand J Surg.2020 Jul;:1457496920938600. doi: 10.1177/1457496920938600.Epub 2020-07-08.

ニコチン誘発性副腎β-アレスチン1のアップレギュレーションは、タバコに関連した高アルドステロン症を媒介して心機能障害を引き起こす

Nicotine-induced adrenal beta-arrestin1 upregulation mediates tobacco-related hyperaldosteronism leading to cardiac dysfunction.
  • Natalie Cora
  • Jennifer Ghandour
  • Celina Marie Pollard
  • Victoria Lynn Desimine
  • Krysten Elaine Ferraino
  • Janelle Marie Pereyra
  • Rachel Valiente
  • Anastasios Lymperopoulos
  • World J Cardiol.2020 May;12(5):192-202. doi: 10.4330/wjc.v12.i5.192.

インド・チェンナイの都市部における移民建設労働者の間でのたばこ予防・禁煙支援サービスへのアクセスにおける社会的決定要因

Social determinants in access to tobacco prevention and cessation support services among migrant construction workers in Urban Chennai, India.
  • Sree Sucharitha Tirukkovalluri
  • Balaji Arumugam
  • N Gunasekharan
  • E Suganya
  • T Akhshaya Ponsuba
  • Divyadharshini S
  • J Family Med Prim Care.2020 Apr;9(4):1991-1998. JFMPC-9-1991. doi: 10.4103/jfmpc.jfmpc_1072_19.Epub 2020-04-30.

緑内障治療におけるジェネリックと先発品のプロスタグランジンアナログの評価。システマティックレビューとメタアナリシス

Evaluation of Generic versus Original Prostaglandin Analogues in the Treatment of Glaucoma: A Systematic Review and Meta-Analysis.
  • Alvilda T Steensberg
  • Olivia O Müllertz
  • Gianni Virgili
  • Augusto Azuara-Blanco
  • Miriam Kolko
  • Ophthalmol Glaucoma.2020 Jan - Feb;3(1):51-59. S2589-4196(19)30303-5. doi: 10.1016/j.ogla.2019.10.002.Epub 2019-11-02.

発酵黒大麦は、マウスの腸内マイクロバイオームを制御し、抗酸化活性を介して食用油煙による肺障害を改善します

Fermented black barley ameliorates lung injury induced by cooking oil fumes via antioxidant activity and regulation of the intestinal microbiome in mice.
  • Xinwen Ding
  • Li Yang
  • Qi Guan
  • Hui Zeng
  • Chenwei Song
  • Jiayi Wu
  • Lihua Song
  • Ecotoxicol. Environ. Saf..2020 Jun;195:110473. S0147-6513(20)30312-2. doi: 10.1016/j.ecoenv.2020.110473.Epub 2020-03-18.

臨床的に遺伝的変異を解釈するためのホモロジーモデリングを利用した統合的な機械学習アプローチの使用。CACNA1Fを例に挙げる

Using an integrative machine learning approach utilising homology modelling to clinically interpret genetic variants: CACNA1F as an exemplar.
  • Shalaw R Sallah
  • Panagiotis I Sergouniotis
  • Stephanie Barton
  • Simon Ramsden
  • Rachel L Taylor
  • Amro Safadi
  • Mitra Kabir
  • Jamie M Ellingford
  • Nick Lench
  • Simon C Lovell
  • Graeme C M Black
  • Eur. J. Hum. Genet..2020 Apr;10.1038/s41431-020-0623-y. doi: 10.1038/s41431-020-0623-y.Epub 2020-04-20.

スターガルト病における動的固定試験中の固定安定性に対する注意力の影響

The Effect of Attention on Fixation Stability during Dynamic Fixation Testing in Stargardt Disease.
  • Etienne M Schönbach
  • Rupert W Strauss
  • Mohamed I Ahmed
  • Jessica L Janes
  • Artur V Cideciyan
  • David G Birch
  • Janet S Sunness
  • Eberhart Zrenner
  • Michael S Ip
  • Xiangrong Kong
  • SriniVas R Sadda
  • Hendrik P N Scholl
  • Am. J. Ophthalmol..2020 May;S0002-9394(20)30230-0. doi: 10.1016/j.ajo.2020.05.002.Epub 2020-05-10.

食事性果糖は微生物由来のアセテートを介して肝臓のリポジェネシスを養う

Dietary fructose feeds hepatic lipogenesis via microbiota-derived acetate.
  • Steven Zhao
  • Cholsoon Jang
  • Joyce Liu
  • Kahealani Uehara
  • Michael Gilbert
  • Luke Izzo
  • Xianfeng Zeng
  • Sophie Trefely
  • Sully Fernandez
  • Alessandro Carrer
  • Katelyn D Miller
  • Zachary T Schug
  • Nathaniel W Snyder
  • Terence P Gade
  • Paul M Titchenell
  • Joshua D Rabinowitz
  • Kathryn E Wellen
  • Nature.2020 03;579(7800):586-591. 10.1038/s41586-020-2101-7. doi: 10.1038/s41586-020-2101-7.Epub 2020-03-18.

Re.Shen etal.未治療眼における常染色体劣性スターガルト病の自然史：研究と個人レベルのデータのシステマティックレビューとメタアナリシス（Ophthalmology.2019;126:1288-1296）

Re: Shen et al.: Natural history of autosomal recessive Stargardt disease in untreated eyes: a systematic review and meta-analysis of study and individual level data (Ophthalmology. 2019;126:1288-1296).
  • Xiangrong Kong
  • Rupert W Strauss
  • Beatriz Munoz
  • Sheila West
  • Janet Cheetham
  • Hendrik P N Scholl
  • Ophthalmology.2020 May;127(5):e28-e29. S0161-6420(20)30087-7. doi: 10.1016/j.ophtha.2020.01.044.

肝細胞癌後のC型肝炎患者に対する直接作用型抗ウイルス治療の臨床成績はインターフェロン治療と同等である

Clinical outcomes of direct-acting antiviral treatments for hepatitis C patients after hepatocellular carcinoma are equivalent to interferon treatment.
  • Yuki Tahata
  • Ryotaro Sakamori
  • Ayako Urabe
  • Ryoko Yamada
  • Kazuyoshi Ohkawa
  • Naoki Hiramatsu
  • Hideki Hagiwara
  • Masahide Oshita
  • Yasuharu Imai
  • Takahiro Kodama
  • Hayato Hikita
  • Tomohide Tatsumi
  • Tetsuo Takehara
  • Hepatol. Res..2020 Jul;doi: 10.1111/hepr.13547.Epub 2020-07-17.

超変異型実験グリオーマにおける免疫チェックポイント遮断に対する反応の不均一性

Heterogeneity of response to immune checkpoint blockade in hypermutated experimental gliomas.
  • Katrin Aslan
  • Verena Turco
  • Jens Blobner
  • Jana K Sonner
  • Anna Rita Liuzzi
  • Nicolás Gonzalo Núñez
  • Donatella De Feo
  • Philipp Kickingereder
  • Manuel Fischer
  • Ed Green
  • Ahmed Sadik
  • Mirco Friedrich
  • Khwab Sanghvi
  • Michael Kilian
  • Frederik Cichon
  • Lara Wolf
  • Kristine Jähne
  • Anna von Landenberg
  • Lukas Bunse
  • Felix Sahm
  • Daniel Schrimpf
  • Jochen Meyer
  • Allen Alexander
  • Gianluca Brugnara
  • Ralph Röth
  • Kira Pfleiderer
  • Beate Niesler
  • Andreas von Deimling
  • Christiane Opitz
  • Michael O Breckwoldt
  • Sabine Heiland
  • Martin Bendszus
  • Wolfgang Wick
  • Burkhard Becher
  • Michael Platten
  • Nat Commun.2020 02;11(1):931. 10.1038/s41467-020-14642-0. doi: 10.1038/s41467-020-14642-0.Epub 2020-02-18.

circ_0001946は、miR-641/CCND1経路を制御することで、ox-LDL刺激を受けた血管平滑筋細胞の増殖を促進し、アポトーシスを抑制することが示唆された

Circ_0001946 facilitates the proliferation and represses apoptosis of ox-LDL-stimulated Vascular Smooth Muscle Cells via regulating miR-641/CCND1 pathway.
  • Xin-Yong Cai
  • Liang Shao
  • Hong-Min Zhu
  • Yu-Liang Zhan
  • Yun-Xia Wang
  • Wei-Ling Tu
  • Lang Hong
  • Shu Wang
  • Gene.2020 Jul;:144953. S0378-1119(20)30622-3. doi: 10.1016/j.gene.2020.144953.Epub 2020-07-16.

培養塩分がソイルレスシステムで商業的に生産されたSalicornia ramosissimaの栄養組成、抗酸化能および微生物の品質に及ぼす影響

Influence of cultivation salinity in the nutritional composition, antioxidant capacity and microbial quality of Salicornia ramosissima commercially produced in soilless systems.
  • Alexandre R Lima
  • Viana Castañeda-Loaiza
  • Miguel Salazar
  • Carla Nunes
  • Célia Quintas
  • Florinda Gama
  • Maribela Pestana
  • Pedro J Correia
  • Tamára Santos
  • João Varela
  • Luísa Barreira
  • Food Chem.2020 Jul;333:127525. S0308-8146(20)31387-X. doi: 10.1016/j.foodchem.2020.127525.Epub 2020-07-10.

円周方向内視鏡的粘膜下層剥離後の食道狭窄予防のためのポリグリコール酸移植と一時的なステント留置による食道粘膜の自己組織化

Autologous esophageal mucosa with polyglycolic acid transplantation and temporary stent implantation for the prevention of esophageal stenosis after circumferential endoscopic submucosal dissection.
  • Yong Liu
  • Zhengqi Li
  • Lizhou Dou
  • Yueming Zhang
  • Guiqi Wang
  • VideoGIE.2020 Jun;5(6):230-232. S2468-4481(20)30032-1. doi: 10.1016/j.vgie.2020.02.004.Epub 2020-03-20.

脂肪組織の成長を促進するための3Dプリント可能な生体吸収性組織工学チャンバーの設計の根拠

Rationale for the design of 3D-printable bioresorbable tissue-engineering chambers to promote the growth of adipose tissue.
  • Pierre Faglin
  • Marion Gradwohl
  • César Depoortere
  • Nicolas Germain
  • Anne-Sophie Drucbert
  • Stéphanie Brun
  • Claire Nahon
  • Salim Dekiouk
  • Alexandre Rech
  • Nathalie Azaroual
  • Patrice Maboudou
  • Julien Payen
  • Pierre-Marie Danzé
  • Pierre Guerreschi
  • Philippe Marchetti
  • Sci Rep.2020 Jul;10(1):11779. 10.1038/s41598-020-68776-8. doi: 10.1038/s41598-020-68776-8.Epub 2020-07-16.

IQGAP1による足場タンパク質CBP間の相互作用は、遺伝子発現と細胞骨格活性の間のインターフェースを提供する

Interaction between the scaffold proteins CBP by IQGAP1 provides an interface between gene expression and cytoskeletal activity.
  • Simone Kosol
  • Sara Contreras-Martos
  • Alessandro Piai
  • Mihaly Varadi
  • Tamas Lazar
  • Angela Bekesi
  • Pierre Lebrun
  • Isabella C Felli
  • Roberta Pierattelli
  • Peter Tompa
  • Sci Rep.2020 Apr;10(1):5753. 10.1038/s41598-020-62069-w. doi: 10.1038/s41598-020-62069-w.Epub 2020-04-01.

オフィオポゴニンDはストレプトゾトシン誘発糖尿病性腎症ラットの酸化ストレスと炎症反応を抑制することで腎機能を改善する

Ophiopogonin D of Ophiopogon japonicus ameliorates renal function by suppressing oxidative stress and inflammatory response in streptozotocin-induced diabetic nephropathy rats.
  • Yanhong Qiao
  • Haiyan Jiao
  • Feng Wang
  • Huimin Niu
  • Braz. J. Med. Biol. Res..2020;53(7):e9628. S0100-879X2020000700604. doi: 10.1590/1414-431X20209628.Epub 2020-06-03.

特定のgyrA遺伝子変異は，中国北京から分離されたMycobacterium tuberculosis分離株における不一致レボフロキサシン耐性の高い有病率と相関していた

Specific gyrA gene mutations correlate with high prevalence of discordant levofloxacin resistance in Mycobacterium tuberculosis isolates from Beijing, China.
  • Fengmin Huo
  • Yifeng Ma
  • Shanshan Li
  • Yi Xue
  • Yuanyuan Shang
  • Lingling Dong
  • Yunxu Li
  • Yu Pang
  • J Mol Diagn.2020 Jun;S1525-1578(20)30373-1. doi: 10.1016/j.jmoldx.2020.06.010.Epub 2020-06-30.

胃内視鏡的粘膜下層剥離後の遅発性出血のリスクに対する抗凝固薬の影響：多施設共同レトロスペクティブ研究

Influence of anticoagulants on the risk of delayed bleeding after gastric endoscopic submucosal dissection: a multicenter retrospective study.
  • Hideomi Tomida
  • Toshiyuki Yoshio
  • Kimihiro Igarashi
  • Yoshinori Morita
  • Ichiro Oda
  • Takuya Inoue
  • Takuto Hikichi
  • Tetsuya Sumiyoshi
  • Hisashi Doyama
  • Yosuke Tsuji
  • Jun Nishikawa
  • Waku Hatta
  • Tatsuya Mikami
  • Mikitaka Iguchi
  • Kazuki Sumiyama
  • Katsumi Yamamoto
  • Kazuya Kitamura
  • Shiko Kuribayashi
  • Atsushi Yanagitani
  • Toshio Uraoka
  • Tomoyuki Yada
  • Kenkei Hasatani
  • Koichiro Kawaguchi
  • Tomoki Fujita
  • Tsutomu Nishida
  • Yoichi Hiasa
  • Mitsuhiro Fujishiro
  • Gastric Cancer.2020 Jul;10.1007/s10120-020-01105-0. doi: 10.1007/s10120-020-01105-0.Epub 2020-07-18.

BPIFB4 の長寿関連バリアントは、ハンチントン病マウスモデルにおいて、CXCR4 を介した線条体-ミクログリアのクロストークを改善し、病気の進行を抑制する

The longevity-associated variant of BPIFB4 improves a CXCR4-mediated striatum-microglia crosstalk preventing disease progression in a mouse model of Huntington's disease.
  • Alba Di Pardo
  • Elena Ciaglia
  • Monica Cattaneo
  • Anna Maciag
  • Francesco Montella
  • Valentina Lopardo
  • Anna Ferrario
  • Francesco Villa
  • Michele Madonna
  • Enrico Amico
  • Albino Carrizzo
  • Antonio Damato
  • Giuseppe Pepe
  • Federico Marracino
  • Alberto Auricchio
  • Carmine Vecchione
  • Vittorio Maglione
  • Annibale A Puca
  • Cell Death Dis.2020 Jul;11(7):546. 10.1038/s41419-020-02754-w. doi: 10.1038/s41419-020-02754-w.Epub 2020-07-18.

ヒト歯髄幹細胞を用いた異種移植モデルでの下顎骨欠損部の再構築-臨床、放射線学的、組織学的評価

Critical-sized mandibular defect reconstruction using human dental pulp stem cells in a xenograft model-clinical, radiological, and histological evaluation.
  • Juan G Gutiérrez-Quintero
  • Juan Y Durán Riveros
  • Carlos A Martínez Valbuena
  • Sofía Pedraza Alonso
  • J C Munévar
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  • Oral Maxillofac Surg.2020 Jul;10.1007/s10006-020-00862-7. doi: 10.1007/s10006-020-00862-7.Epub 2020-07-10.

C 型肝炎ウイルスによるロングノンコーディング RNA HULC のアップレギュレーションとウイルス複製の制御

Upregulation of the Long Non-Coding RNA HULC by Hepatitis C Virus and its Regulation of Viral Replication.
  • Juria Kitabayashi
  • Takayoshi Shirasaki
  • Tetsuro Shimakami
  • Tomoaki Nishiyama
  • Christoph Welsch
  • Masaya Funaki
  • Kazuhisa Murai
  • Ariunaa Sumiyadorj
  • Hajime Takatori
  • Kazuya Kitamura
  • Kazunori Kawaguchi
  • Kuniaki Arai
  • Taro Yamashita
  • Yoshio Sakai
  • Tatsuya Yamashita
  • Eishiro Mizukoshi
  • Masao Honda
  • Shuichi Kaneko
  • J. Infect. Dis..2020 Jun;jiaa325. doi: 10.1093/infdis/jiaa325.Epub 2020-06-09.

Corrigendendum to "Dedifferentiated fat cells in polyglycolic acid-collagen nerve conduits promote rat facial nerve regeneration" Regen Ther 11 (2019) 240-248

Corrigendum to "Dedifferentiated fat cells in polyglycolic acid-collagen nerve conduits promote rat facial nerve regeneration" [Regen Ther 11 (2019) 240-248].
  • Hiroshi Fujimaki
  • Hajime Matsumine
  • Hironobu Osaki
  • Yoshifumi Ueta
  • Wataru Kamei
  • Mari Shimizu
  • Kazuki Hashimoto
  • Kaori Fujii
  • Tomohiko Kazama
  • Taro Matsumoto
  • Yosuke Niimi
  • Mariko Miyata
  • Hiroyuki Sakurai
  • Regen Ther.2020 Dec;15:35-43. S2352-3204(20)30043-2. doi: 10.1016/j.reth.2020.05.002.Epub 2020-06-10.

大腿骨コンドルの局所軟骨欠損におけるヒアルロナンとポリグリコール酸膜対微小骨折によるマトリックス強化骨髄刺激。多施設共同無作為化対照試験

Matrix-Augmented Bone Marrow Stimulation With a Polyglycolic Acid Membrane With Hyaluronan vs Microfracture in Local Cartilage Defects of the Femoral Condyles: A Multicenter Randomized Controlled Trial.
  • Johannes Glasbrenner
  • Wolf Petersen
  • Michael J Raschke
  • Matthias Steiger
  • René Verdonk
  • Claudio C Castelli
  • Giorgio Zappalà
  • Daniel Fritschy
  • Mirco Herbort
  • Orthop J Sports Med.2020 May;8(5):2325967120922938. 10.1177_2325967120922938. doi: 10.1177/2325967120922938.Epub 2020-05-29.

抗下垂体および抗視床下部自己抗体と炎症および外傷性脳損傷を持つ男性における持続的な性腺機能低下症との関連

Anti-Pituitary and Anti-Hypothalamus Autoantibody Associations with Inflammation and Persistent Hypogonadotropic Hypogonadism in Men with Traumatic Brain Injury.
  • Sushupta M Vijapur
  • Zhihui Yang
  • David J Barton
  • Leah Vaughan
  • Nabil Awan
  • Raj G Kumar
  • Byung-Mo Oh
  • Sarah L Berga
  • Kevin K Wang
  • Amy K Wagner
  • J. Neurotrauma.2020 Jul;37(14):1609-1626. doi: 10.1089/neu.2019.6780.Epub 2020-04-13.

生きたブタの内視鏡下粘膜下解離潰瘍に対するポリグリコール酸シートの貼付におけるエンベロープ法の有効性

Efficacy of the Envelope Method in Applying Polyglycolic Acid Sheets to Post-Endoscopic Submucosal Dissection Ulcers in Living Pigs.
  • Hiroya Sakaguchi
  • Toshitatsu Takao
  • Yoshitaka Takegawa
  • Yuki Koga
  • Kazunori Yamanaka
  • Masataka Sagata
  • Shinwa Tanaka
  • Yoshinori Morita
  • Takashi Toyonaga
  • Yuzo Kodama
  • Clin Endosc.2020 Jul;ce.2020.014. doi: 10.5946/ce.2020.014.Epub 2020-07-16.

5つのETSファミリーメンバー、ELF-1、ETV-4、ETV-3L、ETS-1、およびETS-2は、ヒト白血球関連免疫グロブリン様受容体-1遺伝子の基本的なプロモーター活性をアップレギュレートする

Five ETS family members, ELF-1, ETV-4, ETV-3L, ETS-1, and ETS-2 upregulate human leukocyte-associated immunoglobulin-like receptor-1 gene basic promoter activity.
  • Qizhi Cao
  • Shude Yang
  • Qing Lv
  • Yan Liu
  • Li Li
  • Xiaojie Wu
  • Guiwu Qu
  • Xiaoli He
  • Xiaoshu Zhang
  • Shuqin Sun
  • Boqing Li
  • Jing An
  • Tao Hu
  • Jiangnan Xue
  • Aging (Albany NY).2018 Jun;10(6):1390-1401. 101475. doi: 10.18632/aging.101475.

-アヒル・テンブス・ウイルス RNA の非翻訳領域に存在する-作用配列や二次構造は、キャップに依存しない翻訳やウイルスの増殖に重要な役割を果たしていると考えられています

-acting sequences and secondary structures in untranslated regions of duck Tembusu virus RNA are important for cap-independent translation and viral proliferation.
  • Tao Wang
  • Andres Merits
  • Yuanyuan Wu
  • Mingshu Wang
  • Renyong Jia
  • Dekang Zhu
  • Mafeng Liu
  • Xinxin Zhao
  • Qiao Yang
  • Ying Wu
  • Shaqiu Zhang
  • Yunya Liu
  • Ling Zhang
  • Yanling Yu
  • Leichang Pan
  • Shun Chen
  • Anchun Cheng
  • J. Virol..2020 Jun;JVI.00906-20. doi: 10.1128/JVI.00906-20.Epub 2020-06-10.

妊娠中のコビド-19感染症の母体および周産期の転帰と薬理学的管理：システマティックレビュープロトコル

Maternal and perinatal outcomes and pharmacological management of Covid-19 infection in pregnancy: a systematic review protocol.
  • Binny Thomas
  • Abdulrouf Pallivalapila
  • Wessam El Kassem
  • Asma Tarannum
  • Fatema Al Hail
  • Mohammed Rijims
  • Hussain Parappil
  • Arabo Ibrahim Bayo
  • Shamsa Ahmad
  • Zachariah Nazar
  • Derek Stewart
  • Moza Al Hail
  • Syst Rev.2020 Jul;9(1):161. 10.1186/s13643-020-01418-2. doi: 10.1186/s13643-020-01418-2.Epub 2020-07-18.

ニコチンアミドおよびその代謝物であるN1-メチルニコチンアミドは、多嚢胞性卵巣症候群のラットモデルにおける脂肪組織および卵巣組織の内分泌異常および代謝異常を緩和する

Nicotinamide and its metabolite N1-Methylnicotinamide alleviate endocrine and metabolic abnormalities in adipose and ovarian tissues in rat model of Polycystic Ovary Syndrome.
  • Hamid Reza Nejabati
  • Nasser Samadi
  • Vahideh Shahnazi
  • Aynaz Mihanfar
  • Amir Fattahi
  • Zeinab Latifi
  • Zahra Bahrami-Asl
  • Leila Roshangar
  • Mohammad Nouri
  • Chem. Biol. Interact..2020 Jun;324:109093. S0009-2797(19)31895-2. doi: 10.1016/j.cbi.2020.109093.Epub 2020-04-13.

大気汚染が呼吸器健康治療を受けた学生の教育達成度に与える影響。断面データ連携研究

Impact of air pollution on educational attainment for respiratory health treated students: A cross sectional data linkage study.
  • Amy Mizen
  • Jane Lyons
  • Ai Milojevic
  • Ruth Doherty
  • Paul Wilkinson
  • David Carruthers
  • Ashley Akbari
  • Iain Lake
  • Gwyneth A Davies
  • Mohammad Al Sallakh
  • Richard Fry
  • Lorraine Dearden
  • Sarah E Rodgers
  • Health Place.2020 May;63:102355. S1353-8292(20)30036-8. doi: 10.1016/j.healthplace.2020.102355.Epub 2020-05-12.

副鼻腔の解剖学的変化：慢性鼻副鼻腔炎との関係と重症度への影響-コンピュータ断層撮影を用いた解剖学的・臨床的研究-

Sinonasal anatomical variations: their relationship with chronic rhinosinusitis and effect on the severity of disease-a computerized tomography assisted anatomical and clinical study.
  • Ahmet Kaygusuz
  • Mehmet Haksever
  • Davut Akduman
  • Sündüs Aslan
  • Zeynep Sayar
  • Indian J Otolaryngol Head Neck Surg.2014 Sep;66(3):260-6. 678. doi: 10.1007/s12070-013-0678-y.Epub 2013-10-15.

脳海綿体奇形患者におけるMGC4607/CCM2およびKRIT1/CCM1内の複合的な病原性変異の第一報

First Report of Concomitant Pathogenic Mutations Within MGC4607/CCM2 and KRIT1/CCM1 in a Familiar Cerebral Cavernous Malformation Patient.
  • Gustavo da Fontoura Galvão
  • Elielson Veloso da Silva
  • Fabrícia Lima Fontes-Dantas Pharm
  • Ricardo Castro de Oliveira Filho
  • Soniza Alves-Leon
  • Jorge Marcondes de Souza
  • World Neurosurg.2020 Jun;S1878-8750(20)31438-8. doi: 10.1016/j.wneu.2020.06.170.Epub 2020-06-29.

ジエチレントリアミンペンタ酢酸を介在させた層状二重水酸化物によるMn(II)の効率的吸着とその機構解明」へのコメントJ. Environ.Sci. 85, 56-65"にコメントがあります

Comments on "Efficient adsorption of Mn(II) by layered double hydroxides intercalated with diethylenetriaminepentaacetic acid and the mechanistic study. J. Environ. Sci. 85, 56-65".
  • Xueyong Zhou
  • J Environ Sci (China).2020 04;90:409-410. S1001-0742(20)30015-2. doi: 10.1016/j.jes.2020.01.015.Epub 2020-01-31.

皮膚における紫外線曝露の表皮ゲノムマーカーの非侵襲的評価

Non-invasive assessment of epidermal genomic markers of UV exposure in skin.
  • Elnara Muradova
  • Nishit Patel
  • Brittney Sell
  • Bruna B Bittencourt
  • Sandra S Ojeda
  • Charles H Adelmann
  • Ling Cen
  • Chia-Ho Cheng
  • Jianjun Shen
  • Christel M Davis
  • Erik A Ehli
  • Justin Y Newberg
  • Basil Cherpelis
  • Michael A Black
  • Michael B Mann
  • Samir Mitragotri
  • Kenneth Y Tsai
  • J. Invest. Dermatol..2020 Jun;S0022-202X(20)31657-2. doi: 10.1016/j.jid.2020.05.093.Epub 2020-06-15.

気候変動が花粉やカビのアレルゲンによって誘発される呼吸器アレルギーや喘息に与える影響

The effects of climate change on respiratory allergy and asthma induced by pollen and mold allergens.
  • Gennaro D'Amato
  • Herberto Jose Chong-Neto
  • Olga Patricia Monge Ortega
  • Carolina Vitale
  • Ignacio Ansotegui
  • Nelson Rosario
  • Tari Haathela
  • Carmen Galan
  • Ruby Pawankar
  • Margarita Murrieta
  • Lorenzo Cecchi
  • Christian Bergmann
  • Erminia Ridolo
  • German Ramon
  • Sandra Gonzalez Diaz
  • Maria D'Amato
  • Isabella Annesi-Maesano
  • Allergy.2020 Jun;doi: 10.1111/all.14476.Epub 2020-06-26.

イソフラン-レミフェンタニル麻酔の併用により，重度のてんかんおよび知的障害を有する小児における安静時fMRIが可能となった．

Combined Isoflurane-Remifentanil Anaesthesia Permits Resting-State fMRI in Children with Severe Epilepsy and Intellectual Disability.
  • Aaron E L Warren
  • Andrew Davidson
  • Simon J Vogrin
  • A Simon Harvey
  • Catherine Bailey
  • Linda J Dalic
  • David F Abbott
  • John S Archer
  • Brain Topogr.2020 Jul;10.1007/s10548-020-00782-5. doi: 10.1007/s10548-020-00782-5.Epub 2020-07-04.

インド北東部アッサム州からの高負荷環境での感染者と健康な人との接触における末梢血中のCD4 TH細胞の調節サブセットの頻度

Frequencies of regulatory subsets of CD4 TH cells in peripheral blood in -Infected individuals and healthy contacts in a high-burden setting from Assam, Northeast India.
  • Lahari Saikia
  • Trinayan Deka
  • Pranjal Deori
  • Rasmi Roy
  • Md Ezaz Hussain
  • Reema Nath
  • Indian J Med Microbiol.2019 Jul-Sep;37(3):370-375. IndianJMedMicrobiol_2019_37_3_370_277062. doi: 10.4103/ijmm.IJMM_18_439.

分娩中の女性におけるP-糖タンパク質のキラル識別。フルオキセチンの母体-胎児フェキソフェナジン薬物動態への影響

Chiral Discrimination of P-glycoprotein in Parturient Women: Effect of Fluoxetine on Maternal-Fetal Fexofenadine Pharmacokinetics.
  • Leonardo Pinto
  • Fernanda de Lima Moreira
  • Glauco Henrique Balthazar Nardotto
  • Ricardo Carvalho Cavalli
  • Elaine Christine Dantas Moisés
  • Geraldo Duarte
  • Vera Lucia Lanchote
  • Pharm. Res..2020 Jun;37(7):131. 10.1007/s11095-020-02854-4. doi: 10.1007/s11095-020-02854-4.Epub 2020-06-17.

イラン種複合血液分離株の分子疫学、臨床特性、抗真菌感受性プロファイル、抗真菌抵抗性の分子機構の評価

Evaluation of Molecular Epidemiology, Clinical Characteristics, Antifungal Susceptibility Profiles, and Molecular Mechanisms of Antifungal Resistance of Iranian Species Complex Blood Isolates.
  • Amir Arastehfar
  • Farnaz Daneshnia
  • Mohammad Javad Najafzadeh
  • Ferry Hagen
  • Shahram Mahmoudi
  • Mohammadreza Salehi
  • Hossein Zarrinfar
  • Zahra Namvar
  • Zahra Zareshahrabadi
  • Sadegh Khodavaisy
  • Kamiar Zomorodian
  • Weihua Pan
  • Bart Theelen
  • Markus Kostrzewa
  • Teun Boekhout
  • Cornelia Lass-Flörl
  • Front Cell Infect Microbiol.2020;10:206. doi: 10.3389/fcimb.2020.00206.Epub 2020-05-21.

GIPCで制御されたIGFBP-3は、β1インテグリン経路を介して、inVitroでは造血幹細胞の移行を促進し、inVivoでは門脈高血圧症を促進する

GIPC-Regulated IGFBP-3 Promotes HSC Migration In Vitro and Portal Hypertension In Vivo Through a β1-Integrin Pathway.
  • Usman Yaqoob
  • Fanghong Luo
  • Thomas Greuter
  • Nidhi Jalan Sakrikar
  • Tejasav S Sehrawat
  • Jianwen Lu
  • Xiao Hu
  • Jinhang Gao
  • Enis Kostallari
  • Jingbiao Chen
  • Juan Pablo Arab
  • Sheng Cao
  • Vijay H Shah
  • Cell Mol Gastroenterol Hepatol.2020 May;S2352-345X(20)30075-8. doi: 10.1016/j.jcmgh.2020.05.005.Epub 2020-05-22.

トルコ東地中海地域の皮膚リーシュマニア症流行地域におけるサンドフライ相と媒介種の検出のための昆虫学的調査（トルコ・メルシン県）．

Entomological Survey for the Detection of Sand Fly Fauna and Vector Species in the Cutaneous Leishmaniasis Endemic Area in East Mediterranean Region of Turkey, Mersin Province.
  • M Emin Limoncu
  • I Cüneyt Balcıoğlu
  • Seray Töz
  • Samiye Demir
  • Hakan Kavur
  • Mehmet Karakuş
  • Aslı Tetik Vardarlı
  • Yusuf Özbel
  • J. Med. Entomol..2020 May;tjaa089. doi: 10.1093/jme/tjaa089.Epub 2020-05-29.

ヒトアンジオテンシノーゲンのレニン切断部位に近い2つのアミノ酸は、マウスの血圧と動脈硬化に影響を与えない

Two Amino Acids Proximate to the Renin Cleavage Site of Human Angiotensinogen Do Not Affect Blood Pressure and Atherosclerosis in Mice.
  • Chia-Hua Wu
  • Congqing Wu
  • Deborah A Howatt
  • Jessica J Moorleghen
  • Lisa A Cassis
  • Alan Daugherty
  • Hong S Lu
  • Arterioscler. Thromb. Vasc. Biol..2020 Jul;:ATVBAHA120314048. doi: 10.1161/ATVBAHA.120.314048.Epub 2020-07-09.

てんかん性多発性病変が優先的に関与している神経ネットワークを、病変ネットワークマッピング解析により同定した

Identification of neural networks preferentially engaged by epileptogenic mass lesions through lesion network mapping analysis.
  • Alireza M Mansouri
  • Jürgen Germann
  • Alexandre Boutet
  • Gavin J B Elias
  • Karim Mithani
  • Clement T Chow
  • Brij Karmur
  • George M Ibrahim
  • Mary Pat McAndrews
  • Andres M Lozano
  • Gelareh Zadeh
  • Taufik A Valiante
  • Sci Rep.2020 Jul;10(1):10989. 10.1038/s41598-020-67626-x. doi: 10.1038/s41598-020-67626-x.Epub 2020-07-03.

生細胞におけるニコチン性アセチルコリン受容体活性化に対する薬物効果をモニタリングするためのイオン選択的カーボンナノチューブ電界効果トランジスタ

Ion-Selective Carbon Nanotube Field-Effect Transistors for Monitoring Drug Effects on Nicotinic Acetylcholine Receptor Activation in Live Cells.
  • Youngtak Cho
  • Viet Anh Pham Ba
  • Jin-Young Jeong
  • Yoonji Choi
  • Seunghun Hong
  • Sensors (Basel).2020 Jun;20(13). E3680. doi: 10.3390/s20133680.Epub 2020-06-30.

食餌性オレウロペインとそのアシル誘導体は、正準および非正準のNLRP3 inflammasomes経路を介して、プリスタン誘発SLEマウスの腹膜マクロファージの炎症反応を改善した

Dietary oleuropein and its acyl derivative ameliorate inflammatory response in peritoneal macrophages from pristane-induced SLE mice via canonical and noncanonical NLRP3 inflammasomes pathway.
  • M L Castejón
  • T Montoya
  • C Alarcón-de-la-Lastra
  • A González-Benjumea
  • M V Vázquez-Román
  • M Sánchez-Hidalgo
  • Food Funct.2020 Jul;doi: 10.1039/d0fo00235f.Epub 2020-07-13.

専門家によるセグメンテーションラベルと放射線医学的特徴を備えたがんゲノムアトラス神経膠腫MRIコレクションを進化させる

Advancing The Cancer Genome Atlas glioma MRI collections with expert segmentation labels and radiomic features.
  • Spyridon Bakas
  • Hamed Akbari
  • Aristeidis Sotiras
  • Michel Bilello
  • Martin Rozycki
  • Justin S Kirby
  • John B Freymann
  • Keyvan Farahani
  • Christos Davatzikos
  • Sci Data.2017 09;4:170117. sdata2017117. doi: 10.1038/sdata.2017.117.Epub 2017-09-05.

RET融合陽性の非定型肺カルチノイド患者における選択的RET阻害薬セルペルカチニブ（LOXO-292）の効果

Response to the Selective RET Inhibitor Selpercatinib (LOXO-292) in a Patient With RET Fusion-positive Atypical Lung Carcinoid.
  • Elizabeth M Kander
  • Manisha H Shah
  • Ye Zhou
  • Ashima Goyal
  • Joshua D Palmer
  • Dwight H Owen
  • Konstantin Shilo
  • Gopal Patel
  • Raju R Raval
  • Javier Gonzalez
  • Michele Nguyen
  • Elizabeth Olek
  • Jennifer Kherani
  • S Michael Rothenberg
  • Bhavana Konda
  • Clin Lung Cancer.2020 Jun;S1525-7304(20)30205-9. doi: 10.1016/j.cllc.2020.06.011.Epub 2020-06-18.

AML 由来の細胞外小胞上のパルミトイル化タンパク質は、TLR2/Akt/mTOR シグナルを介して骨髄由来の抑制細胞の分化を促進する

Palmitoylated proteins on AML-derived extracellular vesicles promote myeloid-derived suppressor cell differentiation via TLR2/Akt/mTOR signaling.
  • Sehmus Tohumeken
  • Rebecca Baur
  • Martin Böttcher
  • Andrej Stoll
  • Romy Loschinski
  • Konstantinos Panagiotidis
  • Martina Braun
  • Domenica Saul
  • Simon Völkl
  • Andreas S Baur
  • Heiko Bruns
  • Andreas Mackensen
  • Regina Jitschin
  • Dimitrios Mougiakakos
  • Cancer Res..2020 Jun;canres.0024.2020. doi: 10.1158/0008-5472.CAN-20-0024.Epub 2020-06-30.

トリアミノトリアジン-アクリジン結合体を用いたT:Tミスマッチを標的とする構造的基盤は、CTGリピートDNAにおけるU字型の頭部間四接合を誘導する

Structural Basis for Targeting T:T Mismatch with Triaminotriazine-Acridine Conjugate Induces a U-Shaped Head-to-Head Four-Way Junction in CTG Repeat DNA.
  • Ching-Ming Chien
  • Pei-Ching Wu
  • Roshan Satange
  • Cheng-Chung Chang
  • Zi-Lun Lai
  • Lauren D Hagler
  • Steven C Zimmerman
  • Ming-Hon Hou
  • J. Am. Chem. Soc..2020 Jun;142(25):11165-11172. doi: 10.1021/jacs.0c03591.Epub 2020-06-16.

発作性運動誘発性ジスキネジア（PED）を有するシェットランドシープドッグにおけるミトコンドリアPCK2ミスセンス変異

Mitochondrial PCK2 Missense Variant in Shetland Sheepdogs with Paroxysmal Exercise-Induced Dyskinesia (PED).
  • Jasmin Nessler
  • Petra Hug
  • Paul J J Mandigers
  • Peter A J Leegwater
  • Vidhya Jagannathan
  • Anibh M Das
  • Marco Rosati
  • Kaspar Matiasek
  • Adrian C Sewell
  • Marion Kornberg
  • Marina Hoffmann
  • Petra Wolf
  • Andrea Fischer
  • Andrea Tipold
  • Tosso Leeb
  • Genes (Basel).2020 Jul;11(7). E774. doi: 10.3390/genes11070774.Epub 2020-07-09.

COVID-19パンデミック時の神経筋疾患患者における身体活動の有意な減少：検疫の長期的な影響

Significant reduction of physical activity in patients with neuromuscular disease during COVID-19 pandemic: the long-term consequences of quarantine.
  • Vincenzo Di Stefano
  • Giuseppe Battaglia
  • Valerio Giustino
  • Andrea Gagliardo
  • Michele D'Aleo
  • Ottavio Giannini
  • Antonio Palma
  • Filippo Brighina
  • J. Neurol..2020 Jul;10.1007/s00415-020-10064-6. doi: 10.1007/s00415-020-10064-6.Epub 2020-07-13.

新生児における体外膜酸素化によるフェノバルビタールのクリアランスの急激な増加。パイロット的レトロスペクティブ集団薬物動態解析

Rapid Increase in Clearance of Phenobarbital in Neonates on Extracorporeal Membrane Oxygenation: A Pilot Retrospective Population Pharmacokinetic Analysis.
  • Danica Michaličková
  • Pavla Pokorná
  • Dick Tibboel
  • Ondřej Slanař
  • Catherijne A J Knibbe
  • Elke H J Krekels
  • Pediatr Crit Care Med.2020 Jun;doi: 10.1097/PCC.0000000000002402.Epub 2020-06-26.

水素化物生成-原子吸光分析法による分析に先立ち、サンプルマトリックスから低レベルのヒ素とアンチモンを分離・予備濃縮するための、革新的で実用的な深層共晶溶媒ベースのボルテックスアシストマイクロ抽出手順

Innovative and practical deep eutectic solvent based vortex assisted microextraction procedure for separation and preconcentration of low levels of arsenic and antimony from sample matrix prior to analysis by hydride generation-atomic absorption spectrometry.
  • Nail Altunay
  • Adil Elik
  • Ramazan Gürkan
  • Food Chem.2019 Sep;293:378-386. S0308-8146(19)30814-3. doi: 10.1016/j.foodchem.2019.05.019.Epub 2019-05-04.

三叉神経血管系における制御神経ペプチドとしてのオキシトシン。オキシトシンとオキシトシン受容体の局在、発現、機能

Oxytocin as a regulatory neuropeptide in the trigeminovascular system: Localization, expression and function of oxytocin and oxytocin receptors.
  • Karin Warfvinge
  • Diana N Krause
  • Aida Maddahi
  • Anne-Sofie Grell
  • Jacob Ca Edvinsson
  • Kristian A Haanes
  • Lars Edvinsson
  • Cephalalgia.2020 Jun;:333102420929027. doi: 10.1177/0333102420929027.Epub 2020-06-02.

全エクソームシークエンシングによるTelangiectasiaの患者からの2つの新規遺伝子変異の同定

Identification of Two Novel Mutations in the Gene from Patients with Ataxia-Telangiectasia by Whole Exome Sequencing.
  • Masoud Heidari
  • Morteza Soleyman-Nejad
  • Mohammad H Taskhiri
  • Javad Shahpouri
  • Alireza Isazadeh
  • Roghayyeh Ahangari
  • Ali R Mohamadi
  • Masoumeh Ebrahimi
  • Hadi Karimi
  • Manzar Bolhassani
  • Zahra Karimi
  • Mansour Heidari
  • Curr. Genomics.2019 Nov;20(7):531-534. CG-20-531. doi: 10.2174/1389202920666191107153734.

エクソーム送達されたシンデカン-1は、FAK/p190RhoGAP/RhoA/ROCK/NF-κBシグナル伝達軸と糖鎖増強を介して急性肺損傷を救済します

Exosome-delivered syndecan-1 rescues acute lung injury via a FAK/p190RhoGAP/RhoA/ROCK/NF-κB signaling axis and glycocalyx enhancement.
  • Chuankai Zhang
  • Feng Guo
  • Mengling Chang
  • Zengding Zhou
  • Lei Yi
  • Chengjin Gao
  • Xiaoqin Huang
  • Jingning Huan
  • Exp. Cell Res..2019 11;384(1):111596. S0014-4827(19)30453-7. doi: 10.1016/j.yexcr.2019.111596.Epub 2019-09-02.

アストロサイトアンフォールドタンパク応答が非細胞自律神経変性を引き起こす特異的な反応性状態を誘導する

Astrocyte Unfolded Protein Response Induces a Specific Reactivity State that Causes Non-Cell-Autonomous Neuronal Degeneration.
  • Heather L Smith
  • Oliver J Freeman
  • Adrian J Butcher
  • Staffan Holmqvist
  • Ibrahim Humoud
  • Tobias Schätzl
  • Daniel T Hughes
  • Nicholas C Verity
  • Dean P Swinden
  • Joseph Hayes
  • Lis de Weerd
  • David H Rowitch
  • Robin J M Franklin
  • Giovanna R Mallucci
  • Neuron.2020 03;105(5):855-866.e5. S0896-6273(19)31056-6. doi: 10.1016/j.neuron.2019.12.014.Epub 2020-01-07.

遺伝性フィブリノゲンAα鎖アミロイドーシスにおける臓器移植．フランス人患者の症例シリーズ

Organ Transplantation in Hereditary Fibrinogen A α-Chain Amyloidosis: A Case Series of French Patients.
  • Lara Meyer
  • Marc Ulrich
  • Didier Ducloux
  • Valérie Garrigue
  • Cécile Vigneau
  • Dominique Nochy
  • Guillaume Bobrie
  • Sophie Ferlicot
  • Magalie Colombat
  • Jean-Jacques Boffa
  • Karine Clabault
  • Jeannette Mansour
  • Christiane Mousson
  • Raymond Azar
  • Jean-Louis Bacri
  • Antoine Dürrbach
  • Christian Duvic
  • Khalil El Karoui
  • Maxime Hoffmann
  • Arnaud Lionet
  • Victor Panescu
  • Emmanuelle Plaisier
  • Anderson Ratsimbazafy
  • Dominique Guerrot
  • Laurence Vrigneaud
  • Sophie Valleix
  • Hélène François
  • Am. J. Kidney Dis..2020 Jul;S0272-6386(20)30638-7. doi: 10.1053/j.ajkd.2020.02.445.Epub 2020-07-10.

DNA メチル化バイオマーカーの分析を介した大腸がん検診のための便 DNA 前処理プロトコルの系統的評価

A systematic evaluation of stool DNA preparation protocols for colorectal cancer screening via analysis of DNA methylation biomarkers.
  • Shengnan Jin
  • Qian Ye
  • Yanping Hong
  • Wenqing Dai
  • Chengliang Zhang
  • Weihao Liu
  • Ying Guo
  • Dewen Zhu
  • Zhengzheng Zhang
  • Shiliang Chen
  • Yourong Wang
  • Dandan Li
  • Wen Ma
  • Zhengquan Yang
  • Jinlei Li
  • Zhihai Zheng
  • Ju Luan
  • Xiaoli Wu
  • Feizhao Jiang
  • Chang Xu
  • Chunming Ding
  • Clin. Chem. Lab. Med..2020 Jul;/j/cclm.ahead-of-print/cclm-2020-0300/cclm-2020-0300.xml. doi: 10.1515/cclm-2020-0300.Epub 2020-07-16.

フェンタニルは、オピオイド受容体に依存しないRasおよびSTAT5経路の抑制を介して、急性骨髄性白血病の分化細胞およびコミットされた前駆細胞を抑制します

Fentanyl inhibits acute myeloid leukemia differentiated cells and committed progenitors via opioid receptor-independent suppression of Ras and STAT5 pathways.
  • Shuangbo Dai
  • Xiaoqing Zhang
  • Peng Zhang
  • Xuesong Zheng
  • Qiying Pang
  • Fundam Clin Pharmacol.2020 Jun;doi: 10.1111/fcp.12581.Epub 2020-06-21.

予測モデル開発のための臨床医の手引き：去勢抵抗性前立腺癌患者の実データを用いた症例検討

A clinician's guide for developing a prediction model: a case study using real-world data of patients with castration-resistant prostate cancer.
  • Kevin M Veen
  • Isabel B de Angst
  • Mostafa M Mokhles
  • Hans M Westgeest
  • Malou Kuppen
  • Carin A Uyl-de Groot
  • Winald R Gerritsen
  • Paul J M Kil
  • Johanna J M Takkenberg
  • J. Cancer Res. Clin. Oncol..2020 Aug;146(8):2067-2075. 10.1007/s00432-020-03286-8. doi: 10.1007/s00432-020-03286-8.Epub 2020-06-17.

急性骨髄性白血病の導入療法におけるダウノルビシン対イダルビシンとシタラビンの併用療法の有効性と安全性。無作為化臨床試験のメタアナリシス

The efficacy and safety of daunorubicin versus idarubicin combined with cytarabine for induction therapy in acute myeloid leukemia: A meta-analysis of randomized clinical trials.
  • Hanyu Wang
  • Xueting Xiao
  • Qirong Xiao
  • Yanhong Lu
  • Yong Wu
  • Medicine (Baltimore).2020 Jun;99(24):e20094. 00005792-202006120-00004. doi: 10.1097/MD.0000000000020094.

転移性メラノーマ患者にニボルマブを投与した場合の腫瘍溶解症候群

Tumor lysis syndrome in a patient with metastatic melanoma treated with nivolumab.
  • Saiho Sugimoto
  • Takeshi Terashima
  • Tatsuya Yamashita
  • Noriho Iida
  • Masaaki Kitahara
  • Yuji Hodo
  • Tetsuro Shimakami
  • Hajime Takatori
  • Kuniaki Arai
  • Kazunori Kawaguchi
  • Kazuya Kitamura
  • Taro Yamashita
  • Yoshio Sakai
  • Yukihiro Shirota
  • Katsuaki Sato
  • Eishiro Mizukoshi
  • Masao Honda
  • Kenichi Harada
  • Shuichi Kaneko
  • Clin J Gastroenterol.2020 Jun;10.1007/s12328-020-01164-x. doi: 10.1007/s12328-020-01164-x.Epub 2020-06-27.

肝細胞におけるBcl-xLの発現を調節するインターフェロン-γの分泌を介して、1型自然リンパ球が急性肝障害からマウスを保護する

Type 1 Innate Lymphoid Cells Protect Mice from Acute Liver Injury via Interferon-γ Secretion for Upregulating Bcl-xL Expression in Hepatocytes.
  • Tsukasa Nabekura
  • Luke Riggan
  • Andrew D Hildreth
  • Timothy E O'Sullivan
  • Akira Shibuya
  • Immunity.2020 01;52(1):96-108.e9. S1074-7613(19)30462-5. doi: 10.1016/j.immuni.2019.11.004.Epub 2019-12-03.

インビトロデータから薬物-薬物相互作用や遺伝子型による薬物動態効果を定量的に予測する精度は？CYP2D6とCYP2C19基質を例に網羅的に解析

How precise is quantitative prediction of pharmacokinetic effects due to drug-drug interactions and genotype from in vitro data? A comprehensive analysis on the example CYP2D6 and CYP2C19 substrates.
  • Christof Dücker
  • Jürgen Brockmöller
  • Pharmacol. Ther..2020 Jul;:107629. S0163-7258(20)30159-5. doi: 10.1016/j.pharmthera.2020.107629.Epub 2020-07-16.

歯周骨内欠損の治療における自家骨移植による白血球・血小板リッチフィブリンによる歯周再生 vs 自家骨移植によるエナメル質マトリックス誘導体による歯周再生．無作為化非劣性試験

Periodontal regeneration by leukocyte and platelet-rich fibrin with autogenous bone graft versus enamel matrix derivative with autogenous bone graft in the treatment of periodontal intrabony defects: A randomized non-inferiority trial.
  • Michele Paolantonio
  • Marcella Di Tullio
  • Marta Giraudi
  • Luigi Romano
  • Lorenzo Secondi
  • Giulia Paolantonio
  • Filippo Graziani
  • Andrea Pilloni
  • Paolo De Ninis
  • Beatrice Femminella
  • J. Periodontol..2020 Apr;doi: 10.1002/JPER.19-0533.Epub 2020-04-15.

心筋細胞のホメオドメイン間相互作用型プロテインキナーゼ2は、細胞外シグナル制御キナーゼシグナルを介して心臓の基本機能を維持している

Cardiomyocyte Homeodomain-Interacting Protein Kinase 2 Maintains Basal Cardiac Function via Extracellular Signal-Regulated Kinase Signaling.
  • Yuanjun Guo
  • Jennifer Y Sui
  • Kyungsoo Kim
  • Zhentao Zhang
  • Xiaoyan A Qu
  • Young-Jae Nam
  • Robert N Willette
  • Joey V Barnett
  • Bjorn C Knollmann
  • Thomas Force
  • Hind Lal
  • Circulation.2019 11;140(22):1820-1833. doi: 10.1161/CIRCULATIONAHA.119.040740.Epub 2019-10-04.

前臨床動物モデルにおける抗がん剤としての低分子量ヘパリンの有効性と安全性に関するシステマティックレビュー

A systematic review on the efficacy and safety of low molecular weight heparin as an anticancer therapeutic in preclinical animal models.
  • David Ripsman
  • Dean A Fergusson
  • Joshua Montroy
  • Rebecca C Auer
  • Johnny W Huang
  • Aditi Dobriyal
  • Neil Wesch
  • Marc Carrier
  • Manoj M Lalu
  • Thromb. Res..2020 Jul;195:103-113. S0049-3848(20)30299-1. doi: 10.1016/j.thromres.2020.07.008.Epub 2020-07-08.

ASXL1における腫瘍由来の新形質変異は、BAP1-ASXL1-FOXK1/K2転写ネットワークを損なう

Tumor-derived neomorphic mutations in ASXL1 impairs the BAP1-ASXL1-FOXK1/K2 transcription network.
  • Yu-Kun Xia
  • Yi-Rong Zeng
  • Meng-Li Zhang
  • Peng Liu
  • Fang Liu
  • Hao Zhang
  • Chen-Xi He
  • Yi-Ping Sun
  • Jin-Ye Zhang
  • Cheng Zhang
  • Lei Song
  • Chen Ding
  • Yu-Jie Tang
  • Zhen Yang
  • Chen Yang
  • Pu Wang
  • Kun-Liang Guan
  • Yue Xiong
  • Dan Ye
  • Protein Cell.2020 Jul;10.1007/s13238-020-00754-2. doi: 10.1007/s13238-020-00754-2.Epub 2020-07-18.

CAPS関連Nlrp3対立遺伝子のSlc6a3依存性発現は、加齢マウスにおいて進行性の行動異常と神経炎症をもたらすことが示された

Slc6a3-dependent expression of a CAPS-associated Nlrp3 allele results in progressive behavioral abnormalities and neuroinflammation in aging mice.
  • Katharine M von Herrmann
  • Faith L Anderson
  • Eileen M Martinez
  • Alison L Young
  • Matthew C Havrda
  • J Neuroinflammation.2020 Jul;17(1):213. 10.1186/s12974-020-01866-6. doi: 10.1186/s12974-020-01866-6.Epub 2020-07-17.

原発性高悪性度限局性骨肉腫患者における術前MAP化学療法後の化学療法誘発壊死がイベントフリーおよび全生存期間に及ぼす影響

Impact of chemotherapy-induced necrosis on event-free and overall survival after preoperative MAP chemotherapy in patients with primary high-grade localized osteosarcoma.
  • Yusuke Tsuda
  • Kim Tsoi
  • Michael C Parry
  • Jonathan D Stevenson
  • Tomohiro Fujiwara
  • Vaiyapuri Sumathi
  • Lee M Jeys
  • Bone Joint J.2020 Jun;102-B(6):795-803. doi: 10.1302/0301-620X.102B6.BJJ-2019-1307.R1.

内側限界膜フラップ法を用いて、心不全性末期血管拡張性腫瘍に続発した巨大な全肥厚性黄斑部の閉鎖に成功した

SUCCESSFUL CLOSURE OF A LARGE FULL-THICKNESS MACULAR HOLE SECONDARY TO AN IDIOPATHIC RETINAL VASOPROLIFERATIVE TUMOR USING THE INVERTED INTERNAL LIMITING MEMBRANE FLAP TECHNIQUE.
  • Christelle Grondin
  • Umberto Lorenzi
  • Laurence Beral
  • Sarah Morane
  • Tremeur Guillaumie
  • Thierry David
  • Retin Cases Brief Rep.2020 Jul;doi: 10.1097/ICB.0000000000001015.Epub 2020-07-08.

中国人のゲイ、バイセクシャル、その他、過去1年間に性行為を行ったことのある男性と性行為を行ったことのある男性におけるPrEPの使用率と使用意欲

Uptake and willingness to use PrEP among Chinese gay, bisexual and other men who have sex with men with experience of sexualized drug use in the past year.
  • Zixin Wang
  • Phoenix K H Mo
  • Mary Ip
  • Yuan Fang
  • Joseph T F Lau
  • BMC Infect. Dis..2020 Apr;20(1):299. 10.1186/s12879-020-05024-4. doi: 10.1186/s12879-020-05024-4.Epub 2020-04-22.

ファントムと患者固有の受容基準を用いた治療薬ペア間の空間的一致の評価。Tc-MAA SPECT/Y-Microsphere PETへの応用

Assessing Spatial Concordance Between Theranostic Pairs Using Phantom and Patient-Specific Acceptance Criteria: Application to Tc-MAA SPECT/Y-Microsphere PET.
  • Justin K Mikell
  • Bill S Majdalany
  • Dawn Owen
  • Kelly C Paradis
  • Yuni K Dewaraja
  • Int. J. Radiat. Oncol. Biol. Phys..2019 08;104(5):1133-1140. S0360-3016(19)30633-9. doi: 10.1016/j.ijrobp.2019.04.012.Epub 2019-04-22.

Tenascin-Cは、ヒト乳癌において、インテグリンαvβ1/TGF-β/SMADシグナル軸を介して、線維芽細胞の表現型を高収縮性の筋線維芽細胞へと誘導する

Tenascin-C induces phenotypic changes in fibroblasts to myofibroblasts with high contractility through the integrin αvβ1/TGF-β/SMAD signaling axis in human breast cancer.
  • Daisuke Katoh
  • Yuji Kozuka
  • Aya Noro
  • Tomoko Ogawa
  • Kyoko Imanaka-Yoshida
  • Toshimichi Yoshida
  • Am. J. Pathol..2020 Jul;S0002-9440(20)30329-1. doi: 10.1016/j.ajpath.2020.06.008.Epub 2020-07-07.

Tillandsia aguascalentensis Gardner, 1984 (Poales: Bromeliaceae)のフィトテルマタの中のDisparalona hamata (Birge, 1879) (Cladocera: Chydoridae)の記録

A record of Disparalona hamata (Birge, 1879) (Cladocera: Chydoridae) in phytotelmata of Tillandsia aguascalentensis Gardner, 1984 (Poales: Bromeliaceae).
  • Anna N Neretina
  • Petr G Garibian
  • Martín Romero
  • Demetria M Mondragón
  • Marcelo Silva-Briano
  • Zootaxa.2019 Mar;4567(2):zootaxa.4567.2.7. zootaxa.4567.2.7. doi: 10.11646/zootaxa.4567.2.7.Epub 2019-03-15.

心筋梗塞は、自然免疫のリプログラミングを介して乳がんを加速させる

Myocardial infarction accelerates breast cancer via innate immune reprogramming.
  • Graeme J Koelwyn
  • Alexandra A C Newman
  • Milessa S Afonso
  • Coen van Solingen
  • Emma M Corr
  • Emily J Brown
  • Kathleen B Albers
  • Naoko Yamaguchi
  • Deven Narke
  • Martin Schlegel
  • Monika Sharma
  • Lianne C Shanley
  • Tessa J Barrett
  • Karishma Rahman
  • Valeria Mezzano
  • Edward A Fisher
  • David S Park
  • Jonathan D Newman
  • Daniela F Quail
  • Erik R Nelson
  • Bette J Caan
  • Lee W Jones
  • Kathryn J Moore
  • Nat. Med..2020 Jul;10.1038/s41591-020-0964-7. doi: 10.1038/s41591-020-0964-7.Epub 2020-07-13.

VPAC2受容体の活性化は、PKA依存性のメカニズムにより、マウス皮質ニューロンの軸索伸長を阻害し、樹状突起形成を減少させる

Activation of the VPAC2 Receptor Impairs Axon Outgrowth and Decreases Dendritic Arborization in Mouse Cortical Neurons by a PKA-Dependent Mechanism.
  • Shuto Takeuchi
  • Takuya Kawanai
  • Ryosuke Yamauchi
  • Lu Chen
  • Tatsunori Miyaoka
  • Mei Yamada
  • Satoshi Asano
  • Atsuko Hayata-Takano
  • Takanobu Nakazawa
  • Koji Yano
  • Naotaka Horiguchi
  • Shinsaku Nakagawa
  • Kazuhiro Takuma
  • James A Waschek
  • Hitoshi Hashimoto
  • Yukio Ago
  • Front Neurosci.2020;14:521. doi: 10.3389/fnins.2020.00521.Epub 2020-06-04.

竜眼パルプ由来多糖類の発酵過程における生化学的特性とプレバイオティクス活性の動的変化に関する研究

Dynamic variation in biochemical properties and prebiotic activities of polysaccharides from longan pulp during fermentation process.
  • Fei Huang
  • Ruiyue Hong
  • Ruifen Zhang
  • Lihong Dong
  • Yajuan Bai
  • Lei Liu
  • Xuchao Jia
  • Guangjin Wang
  • Mingwei Zhang
  • Int. J. Biol. Macromol..2019 Jul;132:915-921. S0141-8130(19)30314-9. doi: 10.1016/j.ijbiomac.2019.04.032.Epub 2019-04-05.

多血症ウイルスに対するルキソリチニブ治療の実際の成績

Real-World Outcomes of Ruxolitinib Treatment for Polycythemia Vera.
  • Alexander Coltoff
  • Ruben Mesa
  • Jason Gotlib
  • Jessica Shulman
  • Raajit K Rampal
  • Olivia Siwoski
  • Abdulraheem Yacoub
  • Alison Moliterno
  • Anna Yang
  • Evan Braunstein
  • Aaron T Gerds
  • Gabriela S Hobbs
  • Elliott F Winton
  • Swati Goel
  • Martha Wadleigh
  • Douglas Tremblay
  • Erin Moshier
  • John Mascarenhas
  • Clin Lymphoma Myeloma Leuk.2020 May;S2152-2650(20)30265-2. doi: 10.1016/j.clml.2020.05.019.Epub 2020-05-29.

口腔外胚葉からの複数の下垂体前駆体様袋の形成は、ヘッジホッグシグナル欠損鳥類胚において異所性水晶体の発生を引き起こす

The formation of multiple pituitary pouches from the oral ectoderm causes ectopic lens development in hedgehog signaling-defective avian embryos.
  • Yuki Taira
  • Yuya Ikuta
  • Sachiko Inamori
  • Mitsuo Nunome
  • Mikiharu Nakano
  • Takayuki Suzuki
  • Yoichi Matsuda
  • Masaoki Tsudzuki
  • Machiko Teramoto
  • Hideaki Iida
  • Hisato Kondoh
  • Dev. Dyn..2020 Jul;doi: 10.1002/dvdy.222.Epub 2020-07-07.

ホモアンテセッサーの歯のプロテオーム

The dental proteome of Homo antecessor.
  • Frido Welker
  • Jazmín Ramos-Madrigal
  • Petra Gutenbrunner
  • Meaghan Mackie
  • Shivani Tiwary
  • Rosa Rakownikow Jersie-Christensen
  • Cristina Chiva
  • Marc R Dickinson
  • Martin Kuhlwilm
  • Marc de Manuel
  • Pere Gelabert
  • María Martinón-Torres
  • Ann Margvelashvili
  • Juan Luis Arsuaga
  • Eudald Carbonell
  • Tomas Marques-Bonet
  • Kirsty Penkman
  • Eduard Sabidó
  • Jürgen Cox
  • Jesper V Olsen
  • David Lordkipanidze
  • Fernando Racimo
  • Carles Lalueza-Fox
  • José María Bermúdez de Castro
  • Eske Willerslev
  • Enrico Cappellini
  • Nature.2020 04;580(7802):235-238. 10.1038/s41586-020-2153-8. doi: 10.1038/s41586-020-2153-8.Epub 2020-04-01.

小型哺乳類が保有する外来寄生虫群集におけるゼータ多様性のパターンを、3つの階層スケール、すなわち、分類子不変性とスケール依存性で示した

Patterns of zeta diversity in ectoparasite communities harboured by small mammals at three hierarchical scales: taxon-invariance and scale-dependence.
  • Boris R Krasnov
  • Maxim V Vinarski
  • Natalia P Korallo-Vinarskaya
  • Irina S Khokhlova
  • Oecologia.2020 Apr;192(4):1057-1071. 10.1007/s00442-020-04641-9. doi: 10.1007/s00442-020-04641-9.Epub 2020-04-04.

抗凝固剤ナファモスタットは、細胞融合アッセイシステムにおけるSARS-CoV-2 Sタンパク質媒介の融合を強力に阻害し、細胞型依存性のウイルス感染をin vitroで抑制する

The Anticoagulant Nafamostat Potently Inhibits SARS-CoV-2 S Protein-Mediated Fusion in a Cell Fusion Assay System and Viral Infection In Vitro in a Cell-Type-Dependent Manner.
  • Mizuki Yamamoto
  • Maki Kiso
  • Yuko Sakai-Tagawa
  • Kiyoko Iwatsuki-Horimoto
  • Masaki Imai
  • Makoto Takeda
  • Noriko Kinoshita
  • Norio Ohmagari
  • Jin Gohda
  • Kentaro Semba
  • Zene Matsuda
  • Yasushi Kawaguchi
  • Yoshihiro Kawaoka
  • Jun-Ichiro Inoue
  • Viruses.2020 06;12(6). E629. doi: 10.3390/v12060629.Epub 2020-06-10.

Corrigendendum to "Ambient particulate matter triggers dysfunction of subcellular structures and endothelial cell apoptosis through disruption of redox equilibrium and calcium homeostasis" J. Hazard.Mater.394 (2020) 122439

Corrigendum to "Ambient particulate matter triggers dysfunction of subcellular structures and endothelial cell apoptosis through disruption of redox equilibrium and calcium homeostasis" [J. Hazard. Mater. 394 (2020) 122439].
  • Yan Wang
  • Tianshu Wu
  • Tang Meng
  • J. Hazard. Mater..2020 Jul;402:123316. S0304-3894(20)31305-4. doi: 10.1016/j.jhazmat.2020.123316.Epub 2020-07-16.

骨粗鬆症腰椎におけるポリメチルメタクリレートの容量の異なるセメント注入式ペディクルスクリューの影響：3D有限要素法による解析

Influence of cement-augmented pedicle screws with different volumes of polymethylmethacrylate in osteoporotic lumbar vertebrae over the adjacent segments: a 3D finite element analysis.
  • Hui-Zhi Guo
  • Shun-Cong Zhang
  • Dan-Qing Guo
  • Yan-Huai Ma
  • Kai Yuan
  • Yong-Xian Li
  • Jian-Cheng Peng
  • Jing-Lan Li
  • De Liang
  • Yong-Chao Tang
  • BMC Musculoskelet Disord.2020 Jul;21(1):460. 10.1186/s12891-020-03498-6. doi: 10.1186/s12891-020-03498-6.Epub 2020-07-13.

著者訂正。メルケル細胞ポリオマウイルスは、形質転換および腫瘍形成を調節するために、非カノニカルBAFのLSD1介在性遮断を活性化する

Author Correction: Merkel cell polyomavirus activates LSD1-mediated blockade of non-canonical BAF to regulate transformation and tumorigenesis.
  • Donglim Esther Park
  • Jingwei Cheng
  • John P McGrath
  • Matthew Y Lim
  • Camille Cushman
  • Selene K Swanson
  • Michelle L Tillgren
  • Joao A Paulo
  • Prafulla C Gokhale
  • Laurence Florens
  • Michael P Washburn
  • Patrick Trojer
  • James A DeCaprio
  • Nat. Cell Biol..2020 Jun;22(6):752. 10.1038/s41556-020-0533-9. doi: 10.1038/s41556-020-0533-9.

アロエベラ（Aloe barbadensis Miller）ジュース処理のための熱音波化の適用。機能性および主な生理活性多糖類への影響

Application of thermosonication for Aloe vera (Aloe barbadensis Miller) juice processing: Impact on the functional properties and the main bioactive polysaccharides.
  • Guadalupe Alvarado-Morales
  • Rafael Minjares-Fuentes
  • Juan Carlos Contreras-Esquivel
  • Julio Montañez
  • Jorge Armando Meza-Velázquez
  • Antoni Femenia
  • Ultrason Sonochem.2019 Sep;56:125-133. S1350-4177(19)30259-7. doi: 10.1016/j.ultsonch.2019.03.030.Epub 2019-03-30.

2次元キラルハイブリッド有機無機ペロブスカイトにおけるキラリティ誘起スピン選択性を介した光誘起磁性の光磁気検出

Magneto-Optical Detection of Photoinduced Magnetism via Chirality Induced Spin Selectivity in 2D Chiral Hybrid Organic-Inorganic Perovskites.
  • Zhengjie Huang
  • Brian P Bloom
  • Xiaojuan Ni
  • Zheni Nikolaeva Georgieva
  • Melissa Marciesky
  • Eric Vetter
  • Feng Liu
  • David H Waldeck
  • Dali Sun
  • ACS Nano.2020 Jul;doi: 10.1021/acsnano.0c04017.Epub 2020-07-17.

海水系排水を処理する従属栄養性硝化・好気性脱窒同時処理(SHNAD)プロセスにおける汚染物質除去機構とアンピシリンストレスに対する遺伝的応答の解明

Deciphering pollutants removal mechanisms and genetic responses to ampicillin stress in simultaneous heterotrophic nitrification and aerobic denitrification (SHNAD) process treating seawater-based wastewater.
  • Haoming Wang
  • Jin Li
  • Bo Wang
  • Guanghao Chen
  • Bioresour. Technol..2020 Jul;315:123827. S0960-8524(20)31099-3. doi: 10.1016/j.biortech.2020.123827.Epub 2020-07-13.

シアログリコプロテイン受容体陽性腫瘍のPETイメージングを目的としたフッ素18標識N-アセチルガラクトサミン誘導体FFPGalNAcの合成と生物学的評価

Radiosynthesis and biological evaluation of fluorine-18 labeled N-acetylgalactosamine derivative [F]FPGalNAc for PET imaging of asialoglycoprotein receptor-positive tumors.
  • Penghui Sun
  • Yanjiang Han
  • Yun Zhu
  • Kongzhen Hu
  • Shun Huang
  • Jianer Tan
  • Meng Wang
  • Hubing Wu
  • Ganghua Tang
  • Nucl. Med. Biol..2020 Jun;88-89:1-9. S0969-8051(20)30057-3. doi: 10.1016/j.nucmedbio.2020.06.003.Epub 2020-06-15.

リンパ増殖性新生物に対するCAR T細胞療法の登場。研究を臨床に統合する

The Advent of CAR T-Cell Therapy for Lymphoproliferative Neoplasms: Integrating Research Into Clinical Practice.
  • Marco Cerrano
  • Marco Ruella
  • Miguel-Angel Perales
  • Candida Vitale
  • Danilo Giuseppe Faraci
  • Luisa Giaccone
  • Marta Coscia
  • Molly Maloy
  • Miriam Sanchez-Escamilla
  • Hesham Elsabah
  • Afraa Fadul
  • Enrico Maffini
  • Gianfranco Pittari
  • Benedetto Bruno
  • Front Immunol.2020;11:888. doi: 10.3389/fimmu.2020.00888.Epub 2020-05-12.

解説。学校の排除を減らすための措置を取る：親と子のエイボン縦断的研究（ALSPAC）から学校からの排除に関連して子供と思春期のメンタルヘルスの軌跡 - Tejerina-Arrealら（2020）の解説

Commentary: Taking steps to reduce school exclusions: child and adolescent mental health trajectories in relation to exclusion from school from The Avon Longitudinal Study of Parents and Children (ALSPAC) - a commentary on Tejerina-Arreal et al. (2020).
  • Rona Tutt
  • Child Adolesc Ment Health.2020 Jul;doi: 10.1111/camh.12395.Epub 2020-07-19.

セネガルのメディナ・グーナス（ゲディアウェイ）におけるアジア起源のデングウイルス血清型I型の循環をモバイルラボが明らかにした

Mobile Laboratory Reveals the Circulation of Dengue Virus Serotype I of Asian Origin in Medina Gounass (Guediawaye), Senegal.
  • Idrissa Dieng
  • Boris Gildas Hedible
  • Moussa Moïse Diagne
  • Ahmed Abd El Wahed
  • Cheikh Tidiane Diagne
  • Cheikh Fall
  • Vicent Richard
  • Muriel Vray
  • Manfred Weidmann
  • Ousmane Faye
  • Amadou Alpha Sall
  • Oumar Faye
  • Diagnostics (Basel).2020 Jun;10(6). E408. doi: 10.3390/diagnostics10060408.Epub 2020-06-16.

肺がん、子宮頸がん、頭頸部がんの病理診断の同時発生率を比較するための扁平上皮がん抗原レベルを検出する2つの方法の技術的および臨床的性能

Technical and Clinical Performance of Two Methods to Detect Squamous Cell Carcinoma Antigen Levels for Comparing Pathological Diagnosis Coincidence Rates in Lung, Cervical, and Head and Neck Cancers.
  • Yanming Liu
  • Yue Cao
  • Shan He
  • Wencan Cai
  • Clin. Lab..2020 Jul;66(7). doi: 10.7754/Clin.Lab.2019.190912.

日本都市のプライマリケア病院におけるカルバペネマーゼ産生性Enterobacteralesの糞便担持と分子疫学的特徴

Fecal carriage and molecular epidemiologic characteristics of carbapenemase-producing Enterobacterales in primary care hospital in a Japanese city.
  • Yuki Ohno
  • Akihiro Nakamura
  • Eriko Hashimoto
  • Nobuyoshi Noguchi
  • Gaku Matsumoto
  • Saori Fukuda
  • Noriyuki Abe
  • Shuji Matsuo
  • Masaru Komatsu
  • J. Infect. Chemother..2020 May;S1341-321X(20)30136-7. doi: 10.1016/j.jiac.2020.04.012.Epub 2020-05-30.

夏季温暖化が雌雄のポピュラス・カサヤナの成長、光合成、水分状態に及ぼす影響：性差のある干ばつや暑さに対する耐性を示唆している

Effect of summer warming on growth, photosynthesis and water status in female and male Populus cathayana: implications for sex-specific drought and heat tolerances.
  • Junyan Liu
  • Rong Zhang
  • Xiao Xu
  • Joshua C Fowler
  • Tom E X Miller
  • Tingfa Dong
  • Tree Physiol..2020 May;tpaa069. doi: 10.1093/treephys/tpaa069.Epub 2020-05-30.

ベゴモウイルスの核シャトル蛋白質と相互作用する免疫ハブ。宿主の輸送活動を乗っ取り、相容れない機能を抑制する

A Begomovirus Nuclear Shuttle Protein-Interacting Immune Hub: Hijacking Host Transport Activities and Suppressing Incompatible Functions.
  • Laura G C Martins
  • Gabriel A S Raimundo
  • Nathalia G A Ribeiro
  • Jose Cleydson F Silva
  • Nívea C Euclydes
  • Virgilio A P Loriato
  • Christiane E M Duarte
  • Elizabeth P B Fontes
  • Front Plant Sci.2020;11:398. doi: 10.3389/fpls.2020.00398.Epub 2020-04-08.

早産のリスクがある女性のための出生前コルチコステロイドの低対標準用量の新生児と母体のアウトカム。ランダム化対照試験のシステマティックレビュー

Neonatal and Maternal Outcomes of Lower Versus Standard Doses of Antenatal Corticosteroids for Women at Risk of Preterm Delivery: A Systematic Review of Randomized Controlled Trials.
  • Kiran Ninan
  • Frederick Morfaw
  • Kellie E Murphy
  • Joseph Beyene
  • Sarah D McDonald
  • J Obstet Gynaecol Can.2020 Mar;S1701-2163(20)30265-6. doi: 10.1016/j.jogc.2020.02.127.Epub 2020-03-26.

造血細胞移植後の骨の健康管理。米国移植・細胞治療学会による専門家パネルの意見

Bone Health Management After Hematopoietic Cell Transplantation: An Expert Panel Opinion from the American Society for Transplantation and Cellular Therapy.
  • Merav Bar
  • Susan M Ott
  • E Michael Lewiecki
  • Kyriakie Sarafoglou
  • Joy Y Wu
  • Matthew J Thompson
  • Jonathan J Vaux
  • David R Dean
  • Kenneth G Saag
  • Shahrukh K Hashmi
  • Yoshihiro Inamoto
  • Bhagirathbhai R Dholaria
  • Mohamed A Kharfan-Dabaja
  • Arnon Nagler
  • Cesar Rodriguez
  • Betty K Hamilton
  • Nina Shah
  • Mary E D Flowers
  • Bipin N Savani
  • Paul A Carpenter
  • Biol. Blood Marrow Transplant..2020 Jul;S1083-8791(20)30410-9. doi: 10.1016/j.bbmt.2020.07.001.Epub 2020-07-09.

株DP-Nzc36）由来の食品酵素セルラーゼの安全性評価

Safety evaluation of the food enzyme cellulase from (strain DP-Nzc36).
  • Vittorio Silano
  • José Manuel Barat Baviera
  • Claudia Bolognesi
  • Pier Sandro Cocconcelli
  • Riccardo Crebelli
  • David Michael Gott
  • Konrad Grob
  • Evgenia Lampi
  • Alicja Mortensen
  • Gilles Riviere
  • Inger-Lise Steffensen
  • Christina Tlustos
  • Henk van Loveren
  • Laurence Vernis
  • Holger Zorn
  • Lieve Herman
  • Francesca Marcon
  • Ana Gomes
  • Natália Kovalkovičová
  • Yi Liu
  • Joaquim Maia
  • Andrew Chesson
  • EFSA J.2019 Oct;17(10):e05839. EFS25839. doi: 10.2903/j.efsa.2019.5839.Epub 2019-10-18.

下顎後顎の即時または遅延咬合負荷型非スプリンティングインプラントのインプラント周囲骨の組織学的および組織形態学的評価--サルを対象とした実験的研究

Histologic and histomorphometric evaluation of peri-implant bone of immediate or delayed occlusal-loaded non-splinted implants in the posterior mandible--an experimental study in monkeys.
  • Rie Stokholm
  • Flemming Isidor
  • Jens R Nyengaard
  • Clin Oral Implants Res.2014 Nov;25(11):1311-1318. doi: 10.1111/clr.12274.Epub 2013-10-10.

オーストラリアの未処理排水からSARS-CoV-2の検出を初めて確認。COVID-19のコミュニティでの排水監視のための概念実証

First confirmed detection of SARS-CoV-2 in untreated wastewater in Australia: A proof of concept for the wastewater surveillance of COVID-19 in the community.
  • Warish Ahmed
  • Nicola Angel
  • Janette Edson
  • Kyle Bibby
  • Aaron Bivins
  • Jake W O'Brien
  • Phil M Choi
  • Masaaki Kitajima
  • Stuart L Simpson
  • Jiaying Li
  • Ben Tscharke
  • Rory Verhagen
  • Wendy J M Smith
  • Julian Zaugg
  • Leanne Dierens
  • Philip Hugenholtz
  • Kevin V Thomas
  • Jochen F Mueller
  • Sci. Total Environ..2020 Aug;728:138764. S0048-9697(20)32281-6. doi: 10.1016/j.scitotenv.2020.138764.Epub 2020-04-18.

駆出率が低下した心不全患者と健常対照者における末梢内皮機能の動的変化に対する経口トリグリセリド負荷の急性効果

Acute effects of oral triglyceride load on dynamic changes in peripheral endothelial function in heart failure patients with reduced ejection fraction and healthy controls.
  • Azadeh Shafieesabet
  • Nadja Scherbakov
  • Nicole Ebner
  • Anja Sandek
  • Stefanie Lokau
  • Stephan von Haehling
  • Stefan D Anker
  • Mitja Lainscak
  • Ulrich Laufs
  • Wolfram Doehner
  • Nutr Metab Cardiovasc Dis.2020 Jun;S0939-4753(20)30211-8. doi: 10.1016/j.numecd.2020.05.018.Epub 2020-06-02.

チオアセトアミド誘発性急性肝障害および高アンモニア血症に対するLactobacillus salivarius Li01の保護効果

Protective effect of Lactobacillus salivarius Li01 on thioacetamide-induced acute liver injury and hyperammonaemia.
  • Liya Yang
  • Xiaoyuan Bian
  • Wenrui Wu
  • Longxian Lv
  • Yating Li
  • Jianzhong Ye
  • Xianwan Jiang
  • Qing Wang
  • Ding Shi
  • Daiqiong Fang
  • Jingjing Wu
  • Kaicen Wang
  • Qiangqiang Wang
  • Jiafeng Xia
  • Jiaojiao Xie
  • Yanmeng Lu
  • Lanjuan Li
  • Microb Biotechnol.2020 Jul;doi: 10.1111/1751-7915.13629.Epub 2020-07-11.

前浸潤性肺腺癌のゲノムおよび免疫プロファイリング

Genomic and immune profiling of pre-invasive lung adenocarcinoma.
  • Haiquan Chen
  • Jian Carrot-Zhang
  • Yue Zhao
  • Haichuan Hu
  • Samuel S Freeman
  • Su Yu
  • Gavin Ha
  • Alison M Taylor
  • Ashton C Berger
  • Lindsay Westlake
  • Yuanting Zheng
  • Jiyang Zhang
  • Aruna Ramachandran
  • Qiang Zheng
  • Yunjian Pan
  • Difan Zheng
  • Shanbo Zheng
  • Chao Cheng
  • Muyu Kuang
  • Xiaoyan Zhou
  • Yang Zhang
  • Hang Li
  • Ting Ye
  • Yuan Ma
  • Zhendong Gao
  • Xiaoting Tao
  • Han Han
  • Jun Shang
  • Ying Yu
  • Ding Bao
  • Yechao Huang
  • Xiangnan Li
  • Yawei Zhang
  • Jiaqing Xiang
  • Yihua Sun
  • Yuan Li
  • Andrew D Cherniack
  • Joshua D Campbell
  • Leming Shi
  • Matthew Meyerson
  • Nat Commun.2019 11;10(1):5472. 10.1038/s41467-019-13460-3. doi: 10.1038/s41467-019-13460-3.Epub 2019-11-29.

原発性進行性失語症の進行性意味変異における初期の機能的MRI変化：縦断的な症例報告

Early functional MRI changes in a prodromal semantic variant of primary progressive aphasia: a longitudinal case report.
  • Elisa Canu
  • Valentina Bessi
  • Davide Calderaro
  • David Simoni
  • Veronica Castelnovo
  • Michela Leocadi
  • Sonia Padiglioni
  • Salvatore Mazzeo
  • Camilla Cividini
  • Benedetta Nacmias
  • Sandro Sorbi
  • Massimo Filippi
  • Federica Agosta
  • J. Neurol..2020 Jul;10.1007/s00415-020-10053-9. doi: 10.1007/s00415-020-10053-9.Epub 2020-07-10.

14CO2排泄量の多いブラインドループ症候群の空腸液から分離された細菌の脱結合能--呼気分析法と薄層クロマトグラフィーを用いて

The deconjugation ability of bacteria isolated from the jejunal fluids in the blind loop syndrome with high 14CO2 excretion--using the breath analysis technique and thin-layer chromatography.
  • K Shindo
  • R Yamazaki
  • T Mizuno
  • H Shionoiri
  • M Sugiyama
  • Life Sci..1989;45(24):2275-83. 0024-3205(89)90109-4. doi: 10.1016/0024-3205(89)90109-4.

コーンビームコンピュータ断層撮影法を用いた画像誘導型骨盤放射線治療のための固定化装置としての熱可塑性マスクとニーウェッジの比較

Comparison of thermoplastic masks and knee wedge as immobilization devices for image-guided pelvic radiation therapy using Cone Beam Computed Tomography.
  • Mridul Anand
  • Ankita Parikh
  • Sonal P Shah
  • Indian J Cancer.2020 Apr-Jun;57(2):182-186. IndianJournalofCancer_2020_57_2_182_284480. doi: 10.4103/ijc.IJC_602_18.

放射線誘発性肝損傷後の肝再生は、ゲッティンゲンミニブタのPETによる肝胆汁分泌量の増加と関連している

Hepatic regeneration following radiation-induced liver injury is associated with increased hepatobiliary secretion measured by PET in Göttingen minipigs.
  • Kristoffer Kjærgaard
  • Britta Weber
  • Aage Kristian Olsen Alstrup
  • Jørgen Breede Baltzer Petersen
  • Rune Hansen
  • Stephen Jacques Hamilton-Dutoit
  • Frank Viborg Mortensen
  • Michael Sørensen
  • Sci Rep.2020 Jul;10(1):10858. 10.1038/s41598-020-67609-y. doi: 10.1038/s41598-020-67609-y.Epub 2020-07-02.

返信します。コロナウイルス疾患2019（COVID-19）パンデミック時に構造的心臓病介入のために紹介された患者に対するトリアージの考慮事項。ACC/SCAIのコンセンサス・ステートメント

Reply: Triage Considerations for Patients Referred for Structural Heart Disease Intervention During the Coronavirus Disease 2019 (COVID-19) Pandemic: An ACC/SCAI Consensus Statement.
  • Pinak B Shah
  • Frederick G P Welt
  • Ehtisham Mahmud
  • Alistair Phillips
  • Saif Anwaruddin
  • JACC Cardiovasc Interv.2020 07;13(13):1607-1608. S1936-8798(20)31234-6. doi: 10.1016/j.jcin.2020.05.035.

アプタマーと5-フルオロウラシルのデュアルロードAgS量子ドットは、CA125抗原の近赤外フォトルミネッセンスターンオン検出のための高感度ラベルフリープローブとして使用されています

Aptamer and 5-fluorouracil dual-loading AgS quantum dots used as a sensitive label-free probe for near-infrared photoluminescence turn-on detection of CA125 antigen.
  • Hui Jin
  • Rijun Gui
  • Jun Gong
  • Wenxue Huang
  • Biosens Bioelectron.2017 Jun;92:378-384. S0956-5663(16)31135-6. doi: 10.1016/j.bios.2016.10.093.Epub 2016-11-02.

感染症の数理モデルを用いて公衆衛生政策に影響を与える。最近の進展と新たな課題

Influencing public health policy with data-informed mathematical models of infectious diseases: Recent developments and new challenges.
  • Amani Alahmadi
  • Sarah Belet
  • Andrew Black
  • Deborah Cromer
  • Jennifer A Flegg
  • Thomas House
  • Pavithra Jayasundara
  • Jonathan M Keith
  • James M McCaw
  • Robert Moss
  • Joshua V Ross
  • Freya M Shearer
  • Sai Thein Than Tun
  • James Walker
  • Lisa White
  • Jason M Whyte
  • Ada W C Yan
  • Alexander E Zarebski
  • Epidemics.2020 May;32:100393. S1755-4365(20)30020-7. doi: 10.1016/j.epidem.2020.100393.Epub 2020-05-17.

RONOZYMEWX（endo-1,4-β-キシラナーゼ）の産卵鶏用飼料添加物としての有効性

Efficacy of RONOZYMEWX (endo-1,4-β-xylanase) as a feed additive for laying hens.
  • Vasileios Bampidis
  • Giovanna Azimonti
  • Maria de Lourdes Bastos
  • Henrik Christensen
  • Birgit Dusemund
  • Maryline Kouba
  • Mojca Kos Durjava
  • Marta López-Alonso
  • Secundino López Puente
  • Francesca Marcon
  • Baltasar Mayo
  • Alena Pechová
  • Mariana Petkova
  • Fernando Ramos
  • Yolanda Sanz
  • Roberto Edoardo Villa
  • Ruud Woutersen
  • Jaume Galobart
  • Orsolya Holczknecht
  • Paola Manini
  • Elisa Pettenati
  • Fabiola Pizzo
  • Jordi Tarrés-Call
  • Montserrat Anguita
  • EFSA J.2019 Nov;17(11):e05919. EFS25919. doi: 10.2903/j.efsa.2019.5919.Epub 2019-11-28.

アロテトラプロイド綿花とその二倍体前駆体におけるヒストン脱アセチラーゼ（HDAC）遺伝子ファミリー。インシリコでの同定、分子解析、複数の生物学的ストレス、DNA損傷、植物ホルモン処理下での遺伝子発現解析

Histone Deacetylase (HDAC) Gene Family in Allotetraploid Cotton and Its Diploid Progenitors: In Silico Identification, Molecular Characterization, and Gene Expression Analysis under Multiple Abiotic Stresses, DNA Damage and Phytohormone Treatments.
  • Muhammad Imran
  • Sarfraz Shafiq
  • Muhammad Kashif Naeem
  • Emilie Widemann
  • Muhammad Zeeshan Munir
  • Kevin B Jensen
  • Richard R-C Wang
  • Int J Mol Sci.2020 Jan;21(1). E321. doi: 10.3390/ijms21010321.Epub 2020-01-03.

変形性膝関節症の治療におけるミャオ伝統技術のクロスボウ針治療の臨床的有効性評価：多施設無作為化比較試験

Clinical efficacy evaluation of a traditional Miao technique of crossbow needle therapy in the treatment of knee osteoarthritis: a multi-center randomized controlled trial.
  • Jing Fu
  • Hong-Cai Shang
  • Li-Ying Wang
  • Chen Zhao
  • Xiao-Fang Yang
  • Wei-Wei Guo
  • Chun-Xia Lu
  • Jin Cui
  • Yan-Ping Wang
  • Trials.2020 Jun;21(1):560. 10.1186/s13063-020-04508-7. doi: 10.1186/s13063-020-04508-7.Epub 2020-06-22.

干ばつと回復期のフローム滲出液タンパク質のプロファイリングは、トマトの血管系における生物学的ストレス応答を明らかにした

Phloem Exudate Protein Profiles during Drought and Recovery Reveal Abiotic Stress Responses in Tomato Vasculature.
  • Aaron J Ogden
  • Jishnu J Bhatt
  • Heather M Brewer
  • Jack Kintigh
  • Samwel M Kariuki
  • Sairam Rudrabhatla
  • Joshua N Adkins
  • Wayne R Curtis
  • Int J Mol Sci.2020 Jun;21(12). E4461. doi: 10.3390/ijms21124461.Epub 2020-06-23.

非転移性の去勢抵抗性前立腺がんにおけるエンザルタミドと生存率

Enzalutamide and Survival in Nonmetastatic, Castration-Resistant Prostate Cancer.
  • Cora N Sternberg
  • Karim Fizazi
  • Fred Saad
  • Neal D Shore
  • Ugo De Giorgi
  • David F Penson
  • Ubirajara Ferreira
  • Eleni Efstathiou
  • Katarzyna Madziarska
  • Michael P Kolinsky
  • Daniel I G Cubero
  • Bettina Noerby
  • Fabian Zohren
  • Xun Lin
  • Katharina Modelska
  • Jennifer Sugg
  • Joyce Steinberg
  • Maha Hussain
  • N. Engl. J. Med..2020 06;382(23):2197-2206. doi: 10.1056/NEJMoa2003892.Epub 2020-05-29.

LVAD支持による機械的心臓アンロード前後のヒト末期心不全におけるレニンアンジオテンシン系の変化

Alterations of the renin angiotensin system in human end-stage heart failure before and after mechanical cardiac unloading by LVAD support.
  • Rebecca Messmann
  • Alexander Dietl
  • Stefan Wagner
  • Oliver Domenig
  • Carsten Jungbauer
  • Andreas Luchner
  • Lars S Maier
  • Simon Schopka
  • Stephan Hirt
  • Christof Schmid
  • Christoph Birner
  • Mol. Cell. Biochem..2020 Jun;10.1007/s11010-020-03787-7. doi: 10.1007/s11010-020-03787-7.Epub 2020-06-20.

クロロキン抵抗性プラスモディウム・ファルシパルムの無性血期に及ぼす選択された地域の薬用植物の影響

Effect of selected local medicinal plants on the asexual blood stage of chloroquine resistant Plasmodium falciparum.
  • Mohd Ridzuan Mohd Abd Razak
  • Adlin Afzan
  • Rosnani Ali
  • Nur Fasihah Amir Jalaluddin
  • Mohd Isa Wasiman
  • Siti Habsah Shiekh Zahari
  • Noor Rain Abdullah
  • Zakiah Ismail
  • BMC Complement Altern Med.2014 Dec;14:492. 1472-6882-14-492. doi: 10.1186/1472-6882-14-492.Epub 2014-12-15.

フルオロピリミジン-2,4-ジヒドロキシ-5-イソプロピルベンズアミドのCRCおよびNSCLCがん細胞に対する抗腫瘍剤としての効果

Fluoropyrimidin-2,4-dihydroxy-5-isopropylbenzamides as antitumor agents against CRC and NSCLC cancer cells.
  • Wei-Cheng Wu
  • Yi-Min Liu
  • Yu-Hsuan Liao
  • Kai-Cheng Hsu
  • Ssu-Ting Lien
  • I-Chung Chen
  • Mei-Jung Lai
  • Yu-Hsuan Li
  • Shiow-Lin Pan
  • Mei-Chuan Chen
  • Jing-Ping Liou
  • Eur J Med Chem.2020 Jul;203:112540. S0223-5234(20)30512-2. doi: 10.1016/j.ejmech.2020.112540.Epub 2020-07-16.

閉塞性睡眠時無呼吸症候群と持続的気道陽圧治療を受けた患者における25-ヒドロキシビタミンDレベル：簡単なレビュー

25-hydroxyvitamin D levels in patients with obstructive sleep apnea and continuous positive airway pressure treatment: a brief review.
  • Dimitra I Siachpazidou
  • Vasileios Stavrou
  • Spyridon Zouridis
  • Eudoxia Gogou
  • Nicholas-Tiberio Economou
  • Chaido Pastaka
  • Chrissi Hatzoglou
  • Konstantinos I Gourgoulianis
  • Sleep Sci.2020 Jan-Mar;13(1):78-83. doi: 10.5935/1984-0063.20190126.

SAMHD1は、ネララビンに対する急性リンパ芽球性白血病の系統特異的応答の重要な調節因子である

SAMHD1 is a key regulator of the lineage-specific response of acute lymphoblastic leukaemias to nelarabine.
  • Tamara Rothenburger
  • Katie-May McLaughlin
  • Tobias Herold
  • Constanze Schneider
  • Thomas Oellerich
  • Florian Rothweiler
  • Andrew Feber
  • Tim R Fenton
  • Mark N Wass
  • Oliver T Keppler
  • Martin Michaelis
  • Jindrich Cinatl
  • Commun Biol.2020 Jun;3(1):324. 10.1038/s42003-020-1052-8. doi: 10.1038/s42003-020-1052-8.Epub 2020-06-24.

タダラフィルは、雄性ラットにおけるNrf2/HO-1経路の活性化と酸化ストレスおよびアポトーシスの抑制を通じて、シスプラチン誘発性生殖毒性を緩和します

Tadalafil alleviates cisplatin-induced reproductive toxicity through the activation of the Nrf2/HO-1 pathway and the inhibition of oxidative stress and apoptosis in male rats.
  • Basel A Abdel-Wahab
  • Saad Ahmad Alkahtani
  • Ehab A M Elagab
  • Reprod. Toxicol..2020 Jul;96:165-174. S0890-6238(20)30174-X. doi: 10.1016/j.reprotox.2020.06.015.Epub 2020-07-01.

治療の可能性を持つHLA制限ヒトサイトメガロウイルス特異的抗体レパートリーの特性化

Characterization of an HLA-restricted and human cytomegalovirus-specific antibody repertoire with therapeutic potential.
  • Moritz Bewarder
  • Gerhard Held
  • Lorenz Thurner
  • Stephan Stilgenbauer
  • Sigrun Smola
  • Klaus-Dieter Preuss
  • Gabi Carbon
  • Birgit Bette
  • Konstantinos Christofyllakis
  • Joerg Thomas Bittenbring
  • Arne Felbel
  • Alexander Hasse
  • Niels Murawski
  • Dominic Kaddu-Mulindwa
  • Frank Neumann
  • Cancer Immunol. Immunother..2020 Aug;69(8):1535-1548. 10.1007/s00262-020-02564-1. doi: 10.1007/s00262-020-02564-1.Epub 2020-04-16.

再発・難治性急性骨髄性白血病における高用量シタラビンとミトキサントロンの役割の再評価

Reassessing the role of high dose cytarabine and mitoxantrone in relapsed/refractory acute myeloid leukemia.
  • Jonathan Canaani
  • Meital Nagar
  • Gabriel Heering
  • Chen Gefen
  • Ronit Yerushalmi
  • Noga Shem-Tov
  • Yulia Volchek
  • Drorit Merkel
  • Abraham Avigdor
  • Avichai Shimoni
  • Ninette Amariglio
  • Gidi Rechavi
  • Arnon Nagler
  • Oncotarget.2020 Jun;11(23):2233-2245. 27618. doi: 10.18632/oncotarget.27618.Epub 2020-06-09.

1,2,3-トリアゾリルメタンボロネート．セファロスポリナーゼに対するβ-ラクタマーゼ阻害剤の構造活性相関の研究

1,2,3-Triazolylmethaneboronate: A Structure Activity Relationship Study of a Class of β-Lactamase Inhibitors against Cephalosporinase.
  • Emilia Caselli
  • Francesco Fini
  • Maria Luisa Introvigne
  • Mattia Stucchi
  • Magdalena A Taracila
  • Erin R Fish
  • Kali A Smolen
  • Philip N Rather
  • Rachel A Powers
  • Bradley J Wallar
  • Robert A Bonomo
  • Fabio Prati
  • ACS Infect Dis.2020 Jul;6(7):1965-1975. doi: 10.1021/acsinfecdis.0c00254.Epub 2020-06-24.

p68とSTAT3のサイレンシングは相乗的にがんの進行を減少させる

Silencing of p68 and STAT3 synergistically diminishes cancer progression.
  • Vida Hashemi
  • Armin Ahmadi
  • Farinaz Malakotikhah
  • Mitra Ghasemi Chaleshtari
  • Mahdi Baghi Moornani
  • Ali Masjedi
  • Mozhdeh Sojoodi
  • Fatemeh Atyabi
  • Afshin Nikkhoo
  • Narges Rostami
  • Behzad Baradaran
  • Gholamreza Azizi
  • Bahman Yousefi
  • Ghasem Ghalamfarsa
  • Farhad Jadidi-Niaragh
  • Life Sci..2020 May;249:117499. S0024-3205(20)30247-2. doi: 10.1016/j.lfs.2020.117499.Epub 2020-03-03.

Ki-67発現と大腸癌の臨床病理学的特徴との関連。システマティックレビューおよびメタアナリシスのためのプロトコル

The association between Ki-67 expression and the clinical pathological characteristics of colorectal cancer: A protocol for a systematic review and meta-analysis.
  • Jing Li
  • Zhi-Ye Liu
  • Hai-Bo Yu
  • Xiu-Sheng Qu
  • Qing Xue
  • Hai-Tao Yu
  • Christina Weeks
  • Medicine (Baltimore).2020 May;99(21):e19996. 00005792-202005220-00019. doi: 10.1097/MD.0000000000019996.

寄生虫種の空間的・時間的変化と寄生虫-宿主相互作用：小型哺乳類に寄生するノミとガンマジッドダニの事例研究

Spatial and temporal turnover of parasite species and parasite-host interactions: a case study with fleas and gamasid mites parasitic on small mammals.
  • Boris R Krasnov
  • Natalia P Korallo-Vinarskaya
  • Maxim V Vinarski
  • Irina S Khokhlova
  • Parasitol. Res..2020 Jul;119(7):2093-2104. 10.1007/s00436-020-06726-z. doi: 10.1007/s00436-020-06726-z.Epub 2020-05-28.

キャッサバジュースの慢性摂取は、ラット黒質細胞の細胞ストレスを誘導する

Chronic consumption of cassava juice induces cellular stress in rat substantia nigra.
  • Christian de Jesús Rosas-Jarquín
  • Eduardo Rivadeneyra-Domínguez
  • Bertha Alicia León-Chávez
  • Rasajna Nadella
  • Aurora Del Carmen Sánchez-García
  • Daniel Rembao-Bojórquez
  • Juan Francisco Rodríguez-Landa
  • Daniel Hernandez-Baltazar
  • Iran J Basic Med Sci.2020 Jan;23(1):93-101. doi: 10.22038/IJBMS.2019.38460.9131.

プレドニゾロンと経口選択的非ステロイド性経口グルココルチコイド受容体モジュレーターAZD9567の抗炎症作用に対する等張用量の推定

Estimation of equipotent doses for anti-inflammatory effects of prednisolone and AZD9567, an oral selective non-steroidal glucocorticoid receptor modulator.
  • Joachim Almquist
  • Muhammad Waqas Sadiq
  • Ulf G Eriksson
  • Tove Hegelund Myrbäck
  • Susanne Prothon
  • Jacob Leander
  • CPT Pharmacometrics Syst Pharmacol.2020 Jun;doi: 10.1002/psp4.12536.Epub 2020-06-05.

ケトーシスを起こしやすい非定型糖尿病患者における軽度のケトアシドーシス危機の治療におけるキャピラリーケトンモニタリングの使用

Use of capillary ketones monitoring in treatment of mild ketotic crisis in people with ketosis-prone atypical diabetes.
  • Eugene Sobngwi
  • Christine Ghislaine G Ngo Ngai
  • Martine Etoa Etoga
  • Eric Lontchi-Yimagou
  • Armand Mbanya
  • Mesmin Dehayem
  • Jean-Claude Mbanya
  • J. Investig. Med..2020 Jul;jim-2019-001267. doi: 10.1136/jim-2019-001267.Epub 2020-07-14.

嚢胞性線維症とメキシコの子供たちのコホートから緑膿菌分離症は、慢性的な表現型への適応を示す

Pseudomonas aeruginosa Isolates From a Cohort of Mexican Children With Cystic Fibrosis Show Adaptation to a Chronic Phenotype.
  • Roberto Rosales-Reyes
  • Marian Rodríguez-Alvarado
  • José Luis Lezana-Fernández
  • Joselin Yleana Sánchez-Lozano
  • Catalina Gayosso-Vázquez
  • Ma Dolores Jarillo-Quijada
  • José Eduardo Toledano-Tableros
  • Martha Jimena Arredondo-Mercado
  • María Dolores Alcántar-Curiel
  • Nilton Lincopan
  • Jorge E Vidal
  • Ricardo Lascurain
  • Miguel A Valvano
  • José Ignacio Santos-Preciado
  • Pediatr. Infect. Dis. J..2020 May;doi: 10.1097/INF.0000000000002714.Epub 2020-05-20.

高脂肪食を与えたマウスの血漿脂質値および腸内マイクロバイオームに及ぼすLactobacillus plantararus Urumuma-SU4発酵青ヘチマの効果

Effects of Lactobacillus plantarum Uruma-SU4 fermented green loofah on plasma lipid levels and gut microbiome of high-fat diet fed mice.
  • Ayane Shikano
  • Takashi Kuda
  • Junna Shibayama
  • Ai Toyama
  • Yuka Ishida
  • Hajime Takahashi
  • Bon Kimura
  • Food Res. Int..2019 07;121:817-824. S0963-9969(18)31022-6. doi: 10.1016/j.foodres.2018.12.065.Epub 2019-01-06.

第3期でもTRAbの上昇がみられた；バセドウ病で放射性ヨード治療を受けた新生児甲状腺機能障害児の母親の症例

TRAb elevations occurred even in the third trimester; a case of a mother of a child with neonatal thyroid dysfunction, who received radioactive iodine therapy for Graves' disease.
  • Nami Suzuki
  • Ai Yoshihara
  • Jaeduk Yoshimura Noh
  • Kazuya Kinoshita
  • Junki Ohnishi
  • Maki Saito
  • Kiminori Sugino
  • Kochi Ito
  • Endocr. J..2020 Jun;doi: 10.1507/endocrj.EJ20-0039.Epub 2020-06-10.

中等度から重度の外傷性脳障害者における入院リハビリテーション後の意図しない中毒による二次的死亡率

Mortality Secondary to Unintentional Poisoning after Inpatient Rehabilitation among Individuals with Moderate to Severe Traumatic Brain Injury.
  • Flora M Hammond
  • Jessica Ketchum
  • Kristen Dams-O'Connor
  • John D Corrigan
  • Cate Miller
  • Juliet Haarbauer-Krupa
  • Mark Faul
  • Lance E Trexler
  • Cynthia Harrison-Felix
  • J. Neurotrauma.2020 Jul;doi: 10.1089/neu.2020.7038.Epub 2020-07-08.

C/EBPβとRUNX2の相互作用は、ヒトの腰部面関節変性症において軟骨細胞のアポトーシスを促進することを明らかにした

Interaction between C/EBPβ and RUNX2 promotes apoptosis of chondrocytes during human lumbar facet joint degeneration.
  • Jinlong Zhang
  • Jiawei Jiang
  • Guofeng Bao
  • Guanhua Xu
  • Lingling Wang
  • Jiajia Chen
  • Chu Chen
  • Chunshuai Wu
  • Pengfei Xue
  • Dawei Xu
  • Yuyu Sun
  • Zhiming Cui
  • J. Mol. Histol..2020 Aug;51(4):401-410. 10.1007/s10735-020-09891-8. doi: 10.1007/s10735-020-09891-8.Epub 2020-07-06.

ホスホジエステラーゼ9Aの阻害は、ハンチントン病をモデルとした野生型およびトランスジェニックラットにおけるコルチコ支柱伝達を促進する

Phosphodiesterase 9A Inhibition Facilitates Corticostriatal Transmission in Wild-Type and Transgenic Rats That Model Huntington's Disease.
  • Shreaya Chakroborty
  • Fredric P Manfredsson
  • Alexander M Dec
  • Peter W Campbell
  • Grace E Stutzmann
  • Vahri Beaumont
  • Anthony R West
  • Front Neurosci.2020;14:466. doi: 10.3389/fnins.2020.00466.Epub 2020-06-03.

腰部脊柱管狭窄症と股関節形成不全に関連した正中弓状靭帯症候群（ダンバー症候群）の専門家間管理：患者の視点

Interprofessional Management of Median Arcuate Ligament Syndrome (Dunbar Syndrome) Related to Lumbar Lordosis and Hip Dysplasia: A Patient's Perspective.
  • Sclinda Lea Janssen
  • Thomas Scholbach
  • Susan Jeno
  • Holte Laurie
  • Mandy Meyer
  • Colin Combs
  • Eur J Case Rep Intern Med.2020;7(7):001605. 1605-1-12722-1-10-20200415. doi: 10.12890/2020_001605.Epub 2020-04-16.

子宮頸癌の中等度リスクのある患者に対して、開腹子宮摘出術後の術後補助療法は必要か？

Is Adjuvant Therapy Necessary for Patients with Intermediate-Risk Cervical Cancer after Open Radical Hysterectomy?
  • Hideaki Yahata
  • Kenzo Sonoda
  • Shusaku Inoue
  • Nobuko Yasutake
  • Keisuke Kodama
  • Hiroshi Yagi
  • Masafumi Yasunaga
  • Tatsuhiro Ohgami
  • Ichiro Onoyama
  • Eisuke Kaneki
  • Kaoru Okugawa
  • Kazuo Asanoma
  • Kiyoko Kato
  • Oncology.2020 Jul;:1-6. 000508569. doi: 10.1159/000508569.Epub 2020-07-17.

加齢奇風湯の包括的なケミカルプロファイリングとネットワーク薬理学に基づくアルツハイマー病の解析

Comprehensive chemical profiling of Jia-Wei-Qi-Fu-Yin and its network pharmacology-based analysis on Alzheimer's disease.
  • Hai-Ming An
  • Da-Rong Huang
  • Hua Yang
  • Xin-Guang Liu
  • Jing Du
  • Yi Li
  • Chao-Ran Li
  • Han-Qing Pang
  • Run-Zhou Liu
  • Chao Peng
  • Ping Li
  • Wen Gao
  • J Pharm Biomed Anal.2020 Jul;189:113467. S0731-7085(20)31353-4. doi: 10.1016/j.jpba.2020.113467.Epub 2020-07-08.

食道扁平上皮癌の食生活や生存率と TGF-β1 および TGF-βR2 の発現の変化は、血液と比較して組織試料中の変化と関連している

Altered expression of TGF-β1 and TGF-βR2 in tissue samples compared to blood is associated with food habits and survival in esophageal squamous cell carcinoma.
  • Jayasree Talukdar
  • Kangkana Kataki
  • Eyashin Ali
  • Bikash Narayan Choudhury
  • Munindra Narayan Baruah
  • Mallika Bhattacharyya
  • Sahana Bhattacharjee
  • Subhash Medhi
  • Curr Probl Cancer.2020 Jul;:100617. S0147-0272(20)30104-5. doi: 10.1016/j.currproblcancer.2020.100617.Epub 2020-07-04.

中国の高齢者集団における日常生活活動における余暇活動と障害：中国縦断的健康長寿調査からのエビデンス

Leisure activities and disability in activities of daily living among the oldest-old Chinese population: evidence from the Chinese Longitudinal Healthy Longevity Study.
  • Zhi-Hao Li
  • Qing Chen
  • Virginia Byers Kraus
  • Dong Shen
  • Xi-Ru Zhang
  • Pei-Dong Zhang
  • Wen-Fang Zhong
  • Yue-Bin Lv
  • Qing-Mei Huang
  • Wei-Qi Song
  • Dong Wang
  • Xian-Bo Wu
  • Xiao-Ming Shi
  • Chen Mao
  • Aging (Albany NY).2020 Jun;12(11):10687-10703. 103287. doi: 10.18632/aging.103287.Epub 2020-06-12.

経皮的大腿骨アクセスを介した内枝アーチ内移植片の左総頸動脈上枝のAntegradeカテーテル治療のためのステアブルシースの使用

Use of a Steerable Sheath for Antegrade Catheterization of a Supra-Aortic Branch of an Inner-Branched Arch Endograft via a Percutaneous Femoral Access.
  • Alberto M Settembrini
  • Tilo Kölbel
  • Fiona Rohlffs
  • Ahmed Eleshra
  • E Sebastian Debus
  • Giuseppe Panuccio
  • J. Endovasc. Ther..2020 Jul;:1526602820939936. doi: 10.1177/1526602820939936.Epub 2020-07-07.

縦断的COVID-19プロファイリングでは、IL-1RAとIL-10は疾患の重症度と関連し、RANTESは軽症度と関連している

Longitudinal COVID-19 profiling associates IL-1RA and IL-10 with disease severity and RANTES with mild disease.
  • Yan Zhao
  • Ling Qin
  • Ping Zhang
  • Kang Li
  • Lianchun Liang
  • Jianping Sun
  • Bin Xu
  • Yanchao Dai
  • Xuemei Li
  • Chi Zhang
  • Yanchun Peng
  • Yingmei Feng
  • Ang Li
  • Zhongjie Hu
  • Haiping Xiang
  • Graham Ogg
  • Ling-Pei Ho
  • Andrew McMichael
  • Ronghua Jin
  • Julian C Knight
  • Tao Dong
  • Yonghong Zhang
  • JCI Insight.2020 07;5(13). 139834. doi: 10.1172/jci.insight.139834.Epub 2020-07-09.

過去45年間のGrijalva - Usumacinta川（メキシコ湾南部）の影響を受けた海域における人為的・自然的な影響

Anthropogenic and natural impacts in the marine area of influence of the Grijalva - Usumacinta River (Southern Gulf of Mexico) during the last 45 years.
  • M L Machain-Castillo
  • A C Ruiz-Fernández
  • R Alonso-Rodríguez
  • J A Sanchez-Cabeza
  • F R Gío-Argáez
  • A Rodríguez-Ramírez
  • R Villegas-Hernández
  • A I Mora-García
  • A P Fuentes-Sánchez
  • J G Cardoso-Mohedano
  • D U Hernández-Becerril
  • K Esqueda-Lara
  • S Santiago-Pérez
  • M A Gómez-Ponce
  • L H Pérez-Bernal
  • Mar. Pollut. Bull..2020 Jul;156:111245. S0025-326X(20)30363-5. doi: 10.1016/j.marpolbul.2020.111245.Epub 2020-05-27.

大動脈弁狭窄症と左室機能障害を有する小児におけるバルーン大動脈弁形成術の早期および中期的なアウトカムを第三次医療機関で実施した

Early and Intermediate-Term Outcome of Balloon Aortic Valvuloplasty in Children With Aortic Stenosis and Left Ventricular Dysfunction at Tertiary Care Hospital.
  • Ram Chand
  • Abdul Sattar Shaikh
  • Naresh Kumar
  • Hussain Korejo
  • Arshad Sohail
  • Veena Kumari
  • Asif A Khan
  • Najma Patel
  • Cureus.2020 May;12(5):e8321. doi: 10.7759/cureus.8321.Epub 2020-05-27.

性転換手術後の乳房インプラント関連未分化大細胞リンパ腫。トランスジェンダー患者集団における症状、管理、および成績のレビュー

Breast Implant-Associated Anaplastic Large Cell Lymphoma Following Gender Reassignment Surgery: A Review of Presentation, Management, and Outcomes in the Transgender Patient Population.
  • Shruti Zaveri
  • Alice Yao
  • Hank Schmidt
  • Eur J Breast Health.2020 Jul;16(3):162-166. ejbh-16-3-162. doi: 10.5152/ejbh.2020.5480.Epub 2020-07-01.

肥育用ニワトリ、産卵用に飼育されたニワトリ、および産卵点まで飼育された小型鳥類のための動物工学的飼料添加物としてのBiomin DC-Pの安全性と有効性

Safety and efficacy of Biomin DC-P as a zootechnical feed additive for chickens for fattening, chickens reared for laying and minor avian species to the point of lay.
  • Vasileios Bampidis
  • Giovanna Azimonti
  • Maria de Lourdes Bastos
  • Henrik Christensen
  • Birgit Dusemund
  • Maryline Kouba
  • Mojca Kos Durjava
  • Marta López-Alonso
  • Secundino López Puente
  • Francesca Marcon
  • Baltasar Mayo
  • Alena Pechová
  • Mariana Petkova
  • Fernando Ramos
  • Yolanda Sanz
  • Roberto Edoardo Villa
  • Ruud Woutersen
  • Andrew Chesson
  • Jürgen Gropp
  • Giovanna Martelli
  • Derek Renshaw
  • Gloria López-Gálvez
  • Alberto Mantovani
  • EFSA J.2019 Jun;17(6):e05724. EFS25724. doi: 10.2903/j.efsa.2019.5724.Epub 2019-06-11.

椎体高回復術を必要とする頸椎および上部胸椎の外傷性骨折や腫瘍性骨折に対する術中スキャナーとニューロナビゲーションの組み合わせは興味がある

The interest of intraoperative scanner coupled to neuronavigation in traumatic or oncologic fractures of the cervical and upper thoracic spine requiring vertebral body height restoring procedures.
  • Simona Mihaela Florea
  • Kaissar Farah
  • Mikael Meyer
  • Henry Dufour
  • Thomas Graillon
  • Stephan Fuentes
  • Neurochirurgie.2020 Jun;S0028-3770(20)30338-6. doi: 10.1016/j.neuchi.2020.03.005.Epub 2020-06-20.

インド小型マングース(Urva auropunctatus)の血液学的、生化学的及び病理組織学的機能に及ぼす環境暴露クロムの毒性影響を評価した

Evaluating toxicity impacts of environmental exposed chromium on small Indian mongoose (Urva auropunctatus) hematological, biochemical and histopathological functioning.
  • Shaista Andleeb
  • Zulfiqar Ahmad
  • Tariq Mahmood
  • Shenxu Bao
  • Abdullah Arif Saeed
  • Sunil Kumar Jha
  • Chemosphere.2020 Jul;259:127485. S0045-6535(20)31679-9. doi: 10.1016/j.chemosphere.2020.127485.Epub 2020-07-01.

GBA関連パーキンソン病。イタリアの大規模コホートにおけるジェノタイプ-フェノタイプ相関の解剖

GBA-Related Parkinson's Disease: Dissection of Genotype-Phenotype Correlates in a Large Italian Cohort.
  • Simona Petrucci
  • Monia Ginevrino
  • Ilaria Trezzi
  • Edoardo Monfrini
  • Lucia Ricciardi
  • Alberto Albanese
  • Micol Avenali
  • Paolo Barone
  • Anna Rita Bentivoglio
  • Vincenzo Bonifati
  • Francesco Bove
  • Laura Bonanni
  • Livia Brusa
  • Cristina Cereda
  • Giovanni Cossu
  • Chiara Criscuolo
  • Giovanna Dati
  • Anna De Rosa
  • Roberto Eleopra
  • Giovanni Fabbrini
  • Laura Fadda
  • Manuela Garbellini
  • Brigida Minafra
  • Marco Onofrj
  • Claudio Pacchetti
  • Ilaria Palmieri
  • Maria Teresa Pellecchia
  • Martina Petracca
  • Marina Picillo
  • Antonio Pisani
  • Annamaria Vallelunga
  • Roberta Zangaglia
  • Alessio Di Fonzo
  • Francesca Morgante
  • Enza Maria Valente
  • Mov. Disord..2020 Jul;doi: 10.1002/mds.28195.Epub 2020-07-13.

がん対策計画における災害に対するレジリエンスと適応能力の強化。プエルトリコから得られた教訓

Strengthening Resilience and Adaptive Capacity to Disasters in Cancer Control Plans: Lessons Learned from Puerto Rico.
  • Ana P Ortiz
  • William A Calo
  • Pablo Mendez-Lazaro
  • Sandra García-Camacho
  • Ana Mercado-Casillas
  • Jessica Cabrera-Márquez
  • Guillermo Tortolero-Luna
  • Cancer Epidemiol. Biomarkers Prev..2020 Jul;29(7):1290-1293. 1055-9965.EPI-19-1067. doi: 10.1158/1055-9965.EPI-19-1067.Epub 2020-04-21.

ダゲスタン鈍鼻毒蛇、（Dwigubsky, 1832）、毒。ベノミクス、抗毒薬、中和アッセイによる抗毒薬による致死・毒性毒活性の評価

Dagestan blunt-nosed viper, (Dwigubsky, 1832), venom. Venomics, antivenomics, and neutralization assays of the lethal and toxic venom activities by anti- and anti- antivenoms.
  • Davinia Pla
  • Sarai Quesada-Bernat
  • Yania Rodríguez
  • Andrés Sánchez
  • Mariángela Vargas
  • Mauren Villalta
  • Susana Mesén
  • Álvaro Segura
  • Denis O Mustafin
  • Yulia A Fomina
  • Ruslan I Al-Shekhadat
  • Juan J Calvete
  • Toxicon X.2020 Jun;6:100035. S2590-1710(20)30013-8. doi: 10.1016/j.toxcx.2020.100035.Epub 2020-04-20.

ベルガザイムP100（エンド-1,4-β-キシラナーゼ）の肥育用、観賞用鳥類、その他の成長中のSuidaeの飼料添加物としての安全性と有効性について

Safety and efficacy of Bergazym P100 (endo-1,4-β-xylanase) as a feed additive for other birds for fattening, ornamental birds and other growing Suidae.
  • Vasileios Bampidis
  • Giovanna Azimonti
  • Maria de Lourdes Bastos
  • Henrik Christensen
  • Birgit Dusemund
  • Maryline Kouba
  • Mojca Kos Durjava
  • Marta López-Alonso
  • Secundino López Puente
  • Francesca Marcon
  • Baltasar Mayo
  • Alena Pechová
  • Mariana Petkova
  • Fernando Ramos
  • Yolanda Sanz
  • Roberto Edoardo Villa
  • Ruud Woutersen
  • Montserrat Anguita
  • Jaume Galobart
  • Paola Manini
  • Fabiola Pizzo
  • Jordi Tarrés-Call
  • Elisa Pettenati
  • Orsolya Holczknecht
  • EFSA J.2019 Jul;17(7):e05781. EFS25781. doi: 10.2903/j.efsa.2019.5781.Epub 2019-07-24.

低強度パルス超音波による心臓拡張機能障害の改善-HFpEF の新規治療法の可能性

Low-intensity pulsed ultrasound ameliorates cardiac diastolic dysfunction in mice-A possible novel therapy for HFpEF.
  • Yuto Monma
  • Tomohiko Shindo
  • Kumiko Eguchi
  • Ryo Kurosawa
  • Yuta Kagaya
  • Yosuke Ikumi
  • Sadamitsu Ichijo
  • Takashi Nakata
  • Satoshi Miyata
  • Ayana Matsumoto
  • Haruka Sato
  • Masahito Miura
  • Hiroshi Kanai
  • Hiroaki Shimokawa
  • Cardiovasc. Res..2020 Jul;cvaa221. doi: 10.1093/cvr/cvaa221.Epub 2020-07-19.

Sepsis Deep Learning技術の日常診療への実世界での統合：実施研究

Real-World Integration of a Sepsis Deep Learning Technology Into Routine Clinical Care: Implementation Study.
  • Mark P Sendak
  • William Ratliff
  • Dina Sarro
  • Elizabeth Alderton
  • Joseph Futoma
  • Michael Gao
  • Marshall Nichols
  • Mike Revoir
  • Faraz Yashar
  • Corinne Miller
  • Kelly Kester
  • Sahil Sandhu
  • Kristin Corey
  • Nathan Brajer
  • Christelle Tan
  • Anthony Lin
  • Tres Brown
  • Susan Engelbosch
  • Kevin Anstrom
  • Madeleine Clare Elish
  • Katherine Heller
  • Rebecca Donohoe
  • Jason Theiling
  • Eric Poon
  • Suresh Balu
  • Armando Bedoya
  • Cara O'Brien
  • JMIR Med Inform.2020 Jul;8(7):e15182. v8i7e15182. doi: 10.2196/15182.Epub 2020-07-15.

先天性心疾患と肺動脈高血圧症を伴う先天性心疾患は、TACHYON（TAiwan congenital heart disease associated with pulmonarY arterial hypertension）レジストリからのアジアのコホート-initial report

Congenital heart disease with pulmonary artery hypertension in an Asian cohort-initial report from TACHYON (TAiwan congenital heart disease associated with pulmonarY arterial hypertension) registry.
  • Shuenn-Nan Chiu
  • Ken-Pen Weng
  • Ming-Chih Lin
  • Jieh-Neng Wang
  • Be-Tau Hwang
  • Zen-Kong Dai
  • Shan-Miao Lin
  • Jeng-Sheng Chang
  • I-Chun Lin
  • Mei-Hwan Wu
  • Chun-Wei Lu
  • Ming-Tai Lin
  • Chun-An Chen
  • Yu-Chuan Hua
  • Jing-Ming Wu
  • Jou-Kou Wang
  • Int. J. Cardiol..2020 Jun;S0167-5273(20)31301-2. doi: 10.1016/j.ijcard.2020.05.086.Epub 2020-06-06.

プロポリス誘導体である-(4-ブロモフェネチル)カフェアミドの酸化ストレス低減効果による紫外線A誘発皮膚アポトーシスと発癌からの保護

Protection against Ultraviolet A-Induced Skin Apoptosis and Carcinogenesis through the Oxidative Stress Reduction Effects of -(4-bromophenethyl) Caffeamide, A Propolis Derivative.
  • Yueh-Hsiung Kuo
  • Hung-Lung Chiang
  • Po-Yuan Wu
  • Yin Chu
  • Qiao-Xin Chang
  • Kuo-Ching Wen
  • Chien-Yih Lin
  • Hsiu-Mei Chiang
  • Antioxidants (Basel).2020 Apr;9(4). E335. doi: 10.3390/antiox9040335.Epub 2020-04-20.

シロアリ生態系から分離されたグラム陽性ポリ塩化ビフェニル分解細菌Rhodococcus erythropolis TA421の2,3-ジヒドロキシビフェニル1,2-ジオキシゲナーゼをコードする複数の遺伝子

Multiple genes encoding 2,3-dihydroxybiphenyl 1,2-dioxygenase in the gram-positive polychlorinated biphenyl-degrading bacterium Rhodococcus erythropolis TA421, isolated from a termite ecosystem.
  • M Maeda
  • S Y Chung
  • E Song
  • T Kudo
  • Appl. Environ. Microbiol..1995 Feb;61(2):549-55.

多剤耐性結核の治療における安全性と有効性のプロファイルが改善されたコンフォメーション拘束型オキサゾリジノンの発見

The Discovery of a Conformationally Constrained Oxazolidinone with Improved Safety and Efficacy Profiles for the Treatment of Multidrug-Resistant Tuberculosis.
  • Hongyi Zhao
  • Bin Wang
  • Lei Fu
  • Gang Li
  • Haijia Lu
  • Yuke Liu
  • Li Sheng
  • Yan Li
  • Baoxi Zhang
  • Yang Lu
  • Chen Ma
  • Haihong Huang
  • Dongfeng Zhang
  • Yu Lu
  • J. Med. Chem..2020 Jul;doi: 10.1021/acs.jmedchem.0c00500.Epub 2020-07-15.

TGF-β/SmadおよびJAK/STAT経路は、肝線維化に対するプロピレングリコールアルギン酸ナトリウム硫酸塩の抗線維化効果に関与している

TGF-β/Smad and JAK/STAT pathways are involved in the anti-fibrotic effects of propylene glycol alginate sodium sulphate on hepatic fibrosis.
  • Shizan Xu
  • Yuqing Mao
  • Jianye Wu
  • Jiao Feng
  • Jingjing Li
  • Liwei Wu
  • Qiang Yu
  • Yuting Zhou
  • Jie Zhang
  • Jiaojiao Chen
  • Jie Ji
  • Kan Chen
  • Fan Wang
  • Weiqi Dai
  • Xiaoming Fan
  • Chuanyong Guo
  • J. Cell. Mol. Med..2020 May;24(9):5224-5237. doi: 10.1111/jcmm.15175.Epub 2020-03-31.

キトサンをベースとした微粒子は、エラグ酸の結腸標的化およびプロアポトーシス活性を増強する

Chitosan-Based Microparticles Enhance Ellagic Acid's Colon Targeting and Proapoptotic Activity.
  • Nabil A Alhakamy
  • Osama A A Ahmed
  • Mallesh Kurakula
  • Giuseppe Caruso
  • Filippo Caraci
  • Hani Z Asfour
  • Anas Alfarsi
  • Basma G Eid
  • Amir I Mohamed
  • Nabil K Alruwaili
  • Wesam H Abdulaal
  • Usama A Fahmy
  • Hani A Alhadrami
  • Basmah M Eldakhakhny
  • Ashraf B Abdel-Naim
  • Pharmaceutics.2020 Jul;12(7). E652. doi: 10.3390/pharmaceutics12070652.Epub 2020-07-09.

Teratocarcinoma-derived growth factor-1（Cripto-1）は、より攻撃的な行動を示す上皮性歯原性病変で過剰発現している

Teratocarcinoma-derived growth factor-1 (Cripto-1) is overexpressed in epithelial odontogenic lesions displaying more aggressive behaviour.
  • Leorik Pereira da Silva
  • Mara Luana Batista Severo
  • Luiz Arthur Barbosa da Silva
  • Hébel Cavalcanti Galvão
  • Lélia Batista de Souza
  • Márcia Cristina da Costa Miguel
  • Oral Maxillofac Surg.2020 Jul;10.1007/s10006-020-00877-0. doi: 10.1007/s10006-020-00877-0.Epub 2020-07-05.

COVID-19 パンデミックが低所得国および中所得国における HIV、結核、マラリアに与える潜在的影響：モデル化研究

Potential impact of the COVID-19 pandemic on HIV, tuberculosis, and malaria in low-income and middle-income countries: a modelling study.
  • Alexandra B Hogan
  • Britta L Jewell
  • Ellie Sherrard-Smith
  • Juan F Vesga
  • Oliver J Watson
  • Charles Whittaker
  • Arran Hamlet
  • Jennifer A Smith
  • Peter Winskill
  • Robert Verity
  • Marc Baguelin
  • John A Lees
  • Lilith K Whittles
  • Kylie E C Ainslie
  • Samir Bhatt
  • Adhiratha Boonyasiri
  • Nicholas F Brazeau
  • Lorenzo Cattarino
  • Laura V Cooper
  • Helen Coupland
  • Gina Cuomo-Dannenburg
  • Amy Dighe
  • Bimandra A Djaafara
  • Christl A Donnelly
  • Jeff W Eaton
  • Sabine L van Elsland
  • Richard G FitzJohn
  • Han Fu
  • Katy A M Gaythorpe
  • William Green
  • David J Haw
  • Sarah Hayes
  • Wes Hinsley
  • Natsuko Imai
  • Daniel J Laydon
  • Tara D Mangal
  • Thomas A Mellan
  • Swapnil Mishra
  • Gemma Nedjati-Gilani
  • Kris V Parag
  • Hayley A Thompson
  • H Juliette T Unwin
  • Michaela A C Vollmer
  • Caroline E Walters
  • Haowei Wang
  • Yuanrong Wang
  • Xiaoyue Xi
  • Neil M Ferguson
  • Lucy C Okell
  • Thomas S Churcher
  • Nimalan Arinaminpathy
  • Azra C Ghani
  • Patrick G T Walker
  • Timothy B Hallett
  • Lancet Glob Health.2020 Jul;S2214-109X(20)30288-6. doi: 10.1016/S2214-109X(20)30288-6.Epub 2020-07-13.