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日本語AIでPubMedを検索

日本語AIでPubMedを検索

PubMedの提供する医学論文データベースを日本語で検索できます。AI(Deep Learning)を活用した機械翻訳エンジンにより、精度高く日本語へ翻訳された論文をご参照いただけます。

2020年07月 みんなが読んでいる論文

白黒ピクセル2値化ヒストグラムソフトを用いた光コヒーレンス・トモグラフィー血管造影:2つの手術手技における黄斑部穴の治癒を評価するための新手技

Optical coherence tomography angiography using the black-and-white pixel binarization histogram software: a new technique for evaluating healing of macular holes in two surgical techniques.
  • Oswaldo Ferreira Moura Brasil
  • Mariana Kawamuro
  • Denise Pardini Marinho
  • Bruna Trench Maia
  • Murilo Ubukata Polizelli
  • Gabriel Pipolo
  • Natalia Trench Maia
  • Rodrigo Dompieri
  • Natasha Ferreira Santos da Cruz
  • Mauricio Maia
  • Int J Retina Vitreous.2020;6:25. 229. doi: 10.1186/s40942-020-00229-w.Epub 2020-07-01.

血小板に富む血漿やシルデナフィルを外用することで、炎症性サイトカインやコラーゲン/TGF-β1経路を調節することで、ラットの創傷治癒を促進し、より良い修復が可能になります

Platelet-rich plasma and/or sildenafil topical applications accelerate and better repair wound healing in rats through regulation of proinflammatory cytokines and collagen/TGF-β1 pathway.
  • Shereen B Gad
  • Mona H Hafez
  • Yasser S El-Sayed
  • Environ Sci Pollut Res Int.2020 Jul;10.1007/s11356-020-10042-5. doi: 10.1007/s11356-020-10042-5.Epub 2020-07-15.

人工知能と肺がん治療の決定:集学的腫瘍委員会の勧告との一致

Artificial intelligence and lung cancer treatment decision: agreement with recommendation of multidisciplinary tumor board.
  • Min-Seok Kim
  • Ha-Young Park
  • Bo-Gun Kho
  • Cheol-Kyu Park
  • In-Jae Oh
  • Young-Chul Kim
  • Seok Kim
  • Ju-Sik Yun
  • Sang-Yun Song
  • Kook-Joo Na
  • Jae-Uk Jeong
  • Mee Sun Yoon
  • Sung-Ja Ahn
  • Su Woong Yoo
  • Sae-Ryung Kang
  • Seong Young Kwon
  • Hee-Seung Bom
  • Woo-Youl Jang
  • In-Young Kim
  • Jong-Eun Lee
  • Won-Gi Jeong
  • Yun-Hyeon Kim
  • Taebum Lee
  • Yoo-Duk Choi
  • Transl Lung Cancer Res.2020 Jun;9(3):507-514. tlcr-09-03-507. doi: 10.21037/tlcr.2020.04.11.

致死例におけるチクングニヤウイルス抗原の臨床的特徴,病理組織学的特徴,組織免疫局在化.

Clinical characteristics, histopathology, and tissue immunolocalization of chikungunya virus antigen in fatal cases.
  • Tyler M Sharp
  • M Kelly Keating
  • Wun-Ju Shieh
  • Julu Bhatnagar
  • Brigid C Bollweg
  • Rebecca Levine
  • Dianna M Blau
  • Jose V Torres
  • Aidsa Rivera
  • Janice Perez-Padilla
  • Jorge Munoz-Jordan
  • Dario Sanabria
  • Marc Fischer
  • Brenda Rivera Garcia
  • Kay M Tomashek
  • Sherif R Zaki
  • Clin. Infect. Dis..2020 Jul;ciaa837. doi: 10.1093/cid/ciaa837.Epub 2020-07-02.

成人がん生存者における化学療法誘発性末梢神経障害の予防と管理。ASCOガイドラインの更新

Prevention and Management of Chemotherapy-Induced Peripheral Neuropathy in Survivors of Adult Cancers: ASCO Guideline Update.
  • Charles L Loprinzi
  • Christina Lacchetti
  • Jonathan Bleeker
  • Guido Cavaletti
  • Cynthia Chauhan
  • Daniel L Hertz
  • Mark R Kelley
  • Antoinette Lavino
  • Maryam B Lustberg
  • Judith A Paice
  • Bryan P Schneider
  • Ellen M Lavoie Smith
  • Mary Lou Smith
  • Thomas J Smith
  • Nina Wagner-Johnston
  • Dawn L Hershman
  • J. Clin. Oncol..2020 Jul;:JCO2001399. doi: 10.1200/JCO.20.01399.Epub 2020-07-14.

台湾の分解性肝硬変患者における漢方薬使用による全死亡率の低下

Decreased overall mortality rate with Chinese herbal medicine usage in patients with decompensated liver cirrhosis in Taiwan.
  • Fuu-Jen Tsai
  • Pei-Yuu Yang
  • Chao-Jung Chen
  • Ju-Pi Li
  • Te-Mao Li
  • Jian-Shiun Chiou
  • Chi-Fung Cheng
  • Po-Heng Chuang
  • Ting-Hsu Lin
  • Chiu-Chu Liao
  • Shao-Mei Huang
  • Bo Ban
  • Wen-Miin Liang
  • Ying-Ju Lin
  • BMC Complement Med Ther.2020 Jul;20(1):221. 10.1186/s12906-020-03010-6. doi: 10.1186/s12906-020-03010-6.Epub 2020-07-14.

多解像度階層型共役ニューラルネットワークを用いたスライド画像におけるDecidual Vasculopathy Identification in Whole Slide Images Using Multi-Resolution Hierarchical Convolutional Neural Networks

Decidual Vasculopathy Identification in Whole Slide Images Using Multi-Resolution Hierarchical Convolutional Neural Networks.
  • Daniel Clymer
  • Stefan Kostadinov
  • Janet Catov
  • Lauren Skvarca
  • Liron Pantanowitz
  • Jonathan Cagan
  • Philip LeDuc
  • Am. J. Pathol..2020 Jul;S0002-9440(20)30337-0. doi: 10.1016/j.ajpath.2020.06.014.Epub 2020-07-14.

肝硬変患者とCOVID-19単独患者との死亡リスクの比較:多施設マッチドコホート

Comparison of mortality risk in patients with cirrhosis and COVID-19 compared with patients with cirrhosis alone and COVID-19 alone: multicentre matched cohort.
  • Jasmohan S Bajaj
  • Guadalupe Garcia-Tsao
  • Scott Biggins
  • Patrick S Kamath
  • Florence Wong
  • Sara McGeorge
  • Jawaid Shaw
  • Meredith Pearson
  • Micheal Chew
  • Andrew Fagan
  • Randolph de la Rosa Rodriguez
  • Janelle Worthington
  • Amy Olofson
  • Vanessa Weir
  • Calvin Trisolini
  • Sarah Dwyer
  • K Rajender Reddy
  • Gut.2020 Jul;gutjnl-2020-322118. doi: 10.1136/gutjnl-2020-322118.Epub 2020-07-13.

インプラント周囲炎の2つの非外科的治療法の短期比較。臼歯周囲炎の臨床的および微生物学的転帰を2因子無作為化比較試験で検討した

Short-term comparison of two non-surgical treatments modalities of peri-implantitis. Clinical and microbiological outcomes in a two-factorial randomised controlled trial.
  • Mauro Merli
  • Francesco Bernardelli
  • Erica Giulianelli
  • Francesco Carinci
  • Giorgia Mariotti
  • Marco Merli
  • Giovanpaolo Pini-Prato
  • Michele Nieri
  • J. Clin. Periodontol..2020 Jul;doi: 10.1111/jcpe.13345.Epub 2020-07-17.

CARMA試験。早期乳児抗レトロウイルス療法のタイミングによる12年後のHIV-1 DNA総量への影響

The CARMA Study: Early Infant Antiretroviral Therapy-Timing Impacts on Total HIV-1 DNA Quantitation 12 Years Later.
  • Caroline Foster
  • Sara Domínguez-Rodríguez
  • Alfredo Tagarro
  • Triantafylia Gkouleli
  • Judith Heaney
  • Sarah Watters
  • Alasdair Bamford
  • Katy Fidler
  • Marisa Navarro
  • Anita De Rossi
  • Paolo Palma
  • Eleni Nastouli
  • Paolo Rossi
  • Carlo Giaquinto
  • Pablo Rojo
  • J Pediatric Infect Dis Soc.2020 Jul;piaa071. doi: 10.1093/jpids/piaa071.Epub 2020-07-17.

COVID-19パンデミック時の肺がん放射線治療に関する実践勧告。ESTRO-ASTROのコンセンサス・ステートメント

Practice Recommendations for Lung Cancer Radiotherapy During the COVID-19 Pandemic: An ESTRO-ASTRO Consensus Statement.
  • Matthias Guckenberger
  • Claus Belka
  • Andrea Bezjak
  • Jeffrey Bradley
  • Megan E Daly
  • Dirk DeRuysscher
  • Rafal Dziadziuszko
  • Corinne Faivre-Finn
  • Michael Flentje
  • Elizabeth Gore
  • Kristin A Higgins
  • Puneeth Iyengar
  • Brian D Kavanagh
  • Sameera Kumar
  • Cecile Le Pechoux
  • Yolande Lievens
  • Karin Lindberg
  • Fiona McDonald
  • Sara Ramella
  • Ramesh Rengan
  • Umberto Ricardi
  • Andreas Rimner
  • George B Rodrigues
  • Steven E Schild
  • Suresh Senan
  • Charles B Simone
  • Ben J Slotman
  • Martin Stuschke
  • Greg Videtic
  • Joachim Widder
  • Sue S Yom
  • David Palma
  • Int. J. Radiat. Oncol. Biol. Phys..2020 07;107(4):631-640. S0360-3016(20)31136-6. doi: 10.1016/j.ijrobp.2020.05.012.

膵臓癌の治療における免疫チェックポイント阻害薬との合理的な併用のための放射線療法の免疫調節的役割の検討

Interrogating the immune-modulating roles of radiation therapy for a rational combination with immune-checkpoint inhibitors in treating pancreatic cancer.
  • Kenji Fujiwara
  • May Tun Saung
  • Hao Jing
  • Brian Herbst
  • MacKenzie Zarecki
  • Stephen Muth
  • Annie Wu
  • Elaine Bigelow
  • Linda Chen
  • Keyu Li
  • Neolle Jurcak
  • Alex B Blair
  • Ding Ding
  • Michael Wichroski
  • Jordan Blum
  • Nathan Cheadle
  • Jennifer Koenitzer
  • Lei Zheng
  • J Immunother Cancer.2020 Jul;8(2). e000351. doi: 10.1136/jitc-2019-000351.

血球貪食性リンパ組織球症はBartonella henselae感染症と関連しており,複数の感受性遺伝子を有する患者では,血球貪食性リンパ組織球症はBartonella henselae感染症と関連していると考えられた.

Hemophagocytic lymphohistiocytosis is associated with Bartonella henselae infection in a patient with multiple susceptibility genes.
  • Tianjun Yang
  • Qing Mei
  • Lei Zhang
  • Zhendong Chen
  • Chunyan Zhu
  • Xiaowei Fang
  • Shike Geng
  • Aijun Pan
  • Ann. Clin. Microbiol. Antimicrob..2020 Jun;19(1):28. 10.1186/s12941-020-00370-2. doi: 10.1186/s12941-020-00370-2.Epub 2020-06-09.

ヒト誘導多能性幹細胞由来の心筋細胞を用いた二次性鉄過負荷心筋症のモデル化

Modeling Secondary Iron Overload Cardiomyopathy with Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes.
  • June-Wha Rhee
  • Hyoju Yi
  • Dilip Thomas
  • Chi Keung Lam
  • Nadjet Belbachir
  • Lei Tian
  • Xulei Qin
  • Jessica Malisa
  • Edward Lau
  • David T Paik
  • Youngkyun Kim
  • Beatrice SeungHye Choi
  • Nazish Sayed
  • Karim Sallam
  • Ronglih Liao
  • Joseph C Wu
  • Cell Rep.2020 Jul;32(2):107886. S2211-1247(20)30867-6. doi: 10.1016/j.celrep.2020.107886.

十文字Cドメイン含有タンパク質5のダウンレギュレーションは、口腔癌PDTXモデルにおけるシリビニンの増殖を抑制することがわかった

Downregulation of Jumonji-C domain-containing protein 5 inhibits proliferation by silibinin in the oral cancer PDTX model.
  • Cheng-Yu Yang
  • Chang-Huei Tsao
  • Cheng-Chih Hsieh
  • Chih-Kung Lin
  • Chun-Shu Lin
  • Yu-Hsuan Li
  • Wei-Chin Chang
  • Jen-Chen Cheng
  • Gu-Jiun Lin
  • Huey-Kang Sytwu
  • Yin-Lai Wang
  • Yuan-Wu Chen
  • PLoS ONE.2020;15(7):e0236101. PONE-D-20-00360. doi: 10.1371/journal.pone.0236101.Epub 2020-07-17.

高齢者(75歳以上)の前治療歴のない進行非扁平上皮非小細胞肺がん患者に対するドセタキセル+ベバシズマブまたはペメトレキセド+ベバシズマブのオープンラベル、多施設共同、無作為化第II相試験。TORG1323

Open-label, multicenter, randomized phase II study on docetaxel plus bevacizumab or pemetrexed plus bevacizumab for treatment of elderly (aged ≥75 years) patients with previously untreated advanced non-squamous non-small cell lung cancer: TORG1323.
  • Toshiyuki Kozuki
  • Naoyuki Nogami
  • Osamu Hataji
  • Yoshio Tsunezuka
  • Nobuhiko Seki
  • Toshiyuki Harada
  • Nobukazu Fujimoto
  • Akihiro Bessho
  • Kei Takamura
  • Kazuhisa Takahashi
  • Miyako Satouchi
  • Terufumi Kato
  • Takehito Shukuya
  • Natsumi Yamashita
  • Hiroaki Okamoto
  • Tetsu Shinkai
  • Transl Lung Cancer Res.2020 Jun;9(3):459-470. tlcr-09-03-459. doi: 10.21037/tlcr.2020.03.29.

全身性エリテマトーデス患者における3学期半ばの羊水中のプロテオミクスバイオマーカーと妊娠の有害な転帰との関連

Proteomic biomarkers in mid-trimester amniotic fluid associated with adverse pregnancy outcomes in patients with systemic lupus erythematosus.
  • Hae Sun Jeon
  • Seung Mi Lee
  • Young Mi Jung
  • Sohee Oh
  • Jin Kyun Park
  • Eun Bong Lee
  • Chan-Wook Park
  • Joong Shin Park
  • Dohyun Han
  • Jong Kwan Jun
  • PLoS ONE.2020;15(7):e0235838. PONE-D-20-04136. doi: 10.1371/journal.pone.0235838.Epub 2020-07-17.

Endurant Stent Graft System Post Approval Study(ENGAGE PAS)からの血管内腹部大動脈瘤修復の指標とフォローアップ費用

Index and follow-up costs of endovascular abdominal aortic aneurysm repair from the Endurant Stent Graft System Post Approval Study (ENGAGE PAS).
  • Chun Li
  • Sarah E Deery
  • Eric L Eisenstein
  • Zhi Ven Fong
  • Kirsten Dansey
  • Linda Davidson-Ray
  • Betsy O'Neal
  • Marc L Schermerhorn
  • J. Vasc. Surg..2020 Jan;S0741-5214(19)32780-6. doi: 10.1016/j.jvs.2019.11.028.Epub 2020-01-18.

COVID-19パンデミック期間中の成人における布製フェイスカバー使用と関連する要因-米国、2020年4月および5月

Factors Associated with Cloth Face Covering Use Among Adults During the COVID-19 Pandemic - United States, April and May 2020.
  • Kiva A Fisher
  • John P Barile
  • Rebecca J Guerin
  • Kayla L Vanden Esschert
  • Alexiss Jeffers
  • Lin H Tian
  • Amanda Garcia-Williams
  • Brian Gurbaxani
  • William W Thompson
  • Christine E Prue
  • MMWR Morb. Mortal. Wkly. Rep..2020 Jul;69(28):933-937. doi: 10.15585/mmwr.mm6928e3.Epub 2020-07-17.

口腔リハビリテーションのためのコンピュータパンタグラフィックトレーシング、突出性咬合器記録、3D-CBCT画像技術を用いた矢状コンディラー誘導角の評価

Evaluation of sagittal condylar guidance angles using computerized pantographic tracings, protrusive interocclusal records, and 3D-CBCT imaging techniques for oral rehabilitation.
  • T A Naqash
  • S Chaturvedi
  • A Yaqoob
  • S Saquib
  • M K Addas
  • M Alfarsi
  • Niger J Clin Pract.2020 Apr;23(4):550-554. NigerJClinPract_2020_23_4_550_281931. doi: 10.4103/njcp.njcp_544_19.

SARSおよびMERSコロナウイルスパパイン様プロテアーゼのプロトン共役コンフォーメーションダイナミクスの評価。ブロードスペクトラム抗ウイルス剤の設計への示唆

Assessment of Proton-Coupled Conformational Dynamics of SARS and MERS Coronavirus Papain-like Proteases: Implication for Designing Broad-Spectrum Antiviral Inhibitors.
  • Jack A Henderson
  • Neha Verma
  • Jana Shen
  • bioRxiv.2020 Jul;2020.06.30.181305. doi: 10.1101/2020.06.30.181305.Epub 2020-07-01.

ミトコンドリアのエネルギー代謝に関連する遺伝子多型は、線維筋痛症のリスクを増加させる

A genetic polymorphism that is associated with mitochondrial energy metabolism increases risk of fibromyalgia.
  • Miranda Al van Tilburg
  • Marc Parisien
  • Richard G Boles
  • Gillian L Drury
  • Julian Smith-Voudouris
  • Vivek Verma
  • Samar Khoury
  • Anne-Julie Chabot-Doré
  • Andrea G Nackley
  • Shad B Smith
  • William E Whitehead
  • Denniz A Zolnoun
  • Gary D Slade
  • Inna Tchivileva
  • William Maixner
  • Luda Diatchenko
  • Pain.2020 Jul;doi: 10.1097/j.pain.0000000000001996.Epub 2020-07-10.

筋浸潤性膀胱癌におけるネオアジュバント化学療法や導入化学療法の最終治療サイクルの前にコンピュータ断層撮影を行っても、病理組織学的転帰を予測することはできず、単一施設のレトロスペクティブ予後調査の結果を反映したものではない

Computerized tomography before the final treatment cycle of neoadjuvant chemotherapy or induction chemotherapy in muscle-invasive urinary bladder cancer, cannot predict pathoanatomical outcomes and does not reflect prognosis-results of a single centre retrospective prognostic study.
  • Haben Mogos
  • Elisabeth Eriksson
  • Johan Styrke
  • Amir Sherif
  • Transl Androl Urol.2020 Jun;9(3):1062-1072. tau-09-03-1062. doi: 10.21037/tau-19-872.

γ-トコフェロールとアスコルビン酸を含むγ-トコフェロールリッチ混合物の新しい組み合わせは、マウスのチロシン硝化関連男性不妊症のケースで生殖能力を回復します

A Novel Combination of γ-Tocopherol-Rich Mixture of Tocopherols and Ascorbic Acid Restores Fertility in Cases of Tyrosine Nitration-Associated Male Infertility in Mice.
  • Eleonora Scarlata
  • Maria C Fernandez
  • Cristian O'Flaherty
  • Antioxidants (Basel).2020 Jul;9(7). E613. doi: 10.3390/antiox9070613.Epub 2020-07-13.

死後7テスラMRIによる白質肥大の検出.画像と組織学的相関関係のボクセル単位での集学的比較

Post-mortem 7 Tesla MRI detection of white matter hyperintensities: A multidisciplinary voxel-wise comparison of imaging and histological correlates.
  • Austyn D Roseborough
  • Kristopher D Langdon
  • Robert Hammond
  • Lauren E Cipriano
  • Stephen H Pasternak
  • Shawn N Whitehead
  • Ali R Khan
  • Neuroimage Clin.2020 Jul;27:102340. S2213-1582(20)30177-7. doi: 10.1016/j.nicl.2020.102340.Epub 2020-07-06.

重層的なプロテオミクス解析により、キナーゼ複合体に対する癌変異の構成と機能的効果が明らかになった

Multi-layered proteomic analyses decode compositional and functional effects of cancer mutations on kinase complexes.
  • Martin Mehnert
  • Rodolfo Ciuffa
  • Fabian Frommelt
  • Federico Uliana
  • Audrey van Drogen
  • Kilian Ruminski
  • Matthias Gstaiger
  • Ruedi Aebersold
  • Nat Commun.2020 Jul;11(1):3563. 10.1038/s41467-020-17387-y. doi: 10.1038/s41467-020-17387-y.Epub 2020-07-16.

酵母ベースのAβ1-15ワクチンは強い免疫原性を示し、アルツハイマー病トランスジェニックマウスの神経病理と認知機能の障害を軽減します

Yeast-Based Aβ1-15 Vaccine Elicits Strong Immunogenicity and Attenuates Neuropathology and Cognitive Deficits in Alzheimer's Disease Transgenic Mice.
  • Dong-Qun Liu
  • Shuai Lu
  • Lun Zhang
  • Ya-Ru Huang
  • Mei Ji
  • Xiao-Ying Sun
  • Xiao-Ge Liu
  • Rui-Tian Liu
  • Vaccines (Basel).2020 Jul;8(3). E351. doi: 10.3390/vaccines8030351.Epub 2020-07-01.

低リスクの非del(5q)骨髄異形成症候群患者におけるレナリドミドに対する反応に及ぼす体細胞変異の影響

Impact of somatic mutations on response to lenalidomide in lower-risk non-del(5q) myelodysplastic syndromes patients.
  • Valeria Santini
  • Pierre Fenaux
  • Aristoteles Giagounidis
  • Uwe Platzbecker
  • Alan F List
  • Torsten Haferlach
  • Jim Zhong
  • Chengqing Wu
  • Konstantinos Mavrommatis
  • C L Beach
  • Kyle J MacBeth
  • Antonio Almeida
  • Leukemia.2020 Jul;10.1038/s41375-020-0961-3. doi: 10.1038/s41375-020-0961-3.Epub 2020-07-13.

Nudix hydrolase遺伝子ファミリーにおける機能の多様化が、Rosa x wichuranaのセスキテルペン生合成を促進している

Functional diversification in the Nudix hydrolase gene family drives sesquiterpene biosynthesis in Rosa x wichurana.
  • Pulu Sun
  • Clément Dégut
  • Stéphane Réty
  • Jean-Claude Caissard
  • Laurence Hibrand-Saint Oyant
  • Aurélie Bony
  • Saretta N Paramita
  • Corentin Conart
  • Jean-Louis Magnard
  • Julien Jeauffre
  • Ahmed M Abd-El-Haliem
  • Jordan Marie-Magdelaine
  • Tatiana Thouroude
  • Raymonde Baltenweck
  • Carine Tisné
  • Fabrice Foucher
  • Michel Haring
  • Philippe Hugueney
  • Robert C Schuurink
  • Sylvie Baudino
  • Plant J..2020 Jul;doi: 10.1111/tpj.14916.Epub 2020-07-08.

Sumatriptanはラットにおけるニトラルギー伝達と5-HT受容体を介して、リチウム-ピロカルピンによって誘発された状態てんかんの重症度を低下させる。薬理学的根拠に基づいたエビデンス

Sumatriptan Reduces Severity of Status Epilepticus Induced by Lithium-Pilocarpine Through Nitrergic Transmission and 5-HT Receptors in Rats: A Pharmacological-Based Evidence.
  • Faezeh Eslami
  • Nastaran Rahimi
  • Aysa Ostovaneh
  • Mehdi Ghasemi
  • Pegah Dejban
  • Ata Abbasi
  • Ahmad Reza Dehpour
  • Fundam Clin Pharmacol.2020 Jul;doi: 10.1111/fcp.12590.Epub 2020-07-13.

フリードライヒ失調症患者を対象とした(+)-エピカテキンの安全性と有効性。第2相、非盲検、プロスペクティブ試験

Safety and Efficacy of (+)-Epicatechin in Subjects with Friedreich's Ataxia: A Phase II, Open-Label, Prospective Study.
  • M Yasir Qureshi
  • Marc C Patterson
  • Vicki Clark
  • Jonathan N Johnson
  • Margaret A Moutvic
  • Sherilyn W Driscoll
  • Jennifer L Kemppainen
  • John Huston
  • Jeff R Anderson
  • Andrew D Badley
  • Peter J Tebben
  • Philip Wackel
  • Devin Oglesbee
  • James Glockner
  • George Schreiner
  • Sundeep Dugar
  • Jillienne C Touchette
  • Ralitza H Gavrilova
  • J. Inherit. Metab. Dis..2020 Jul;doi: 10.1002/jimd.12285.Epub 2020-07-16.

膵臓神経内分泌腫瘍のサーベイランスと医学的管理に関する北米神経内分泌腫瘍学会のコンセンサスガイドライン

The North American Neuroendocrine Tumor Society Consensus Guidelines for Surveillance and Medical Management of Pancreatic Neuroendocrine Tumors.
  • Thorvardur R Halfdanarson
  • Jonathan R Strosberg
  • Laura Tang
  • Andrew M Bellizzi
  • Emily K Bergsland
  • Thomas M OʼDorisio
  • Daniel M Halperin
  • Lauren Fishbein
  • Jennifer Eads
  • Thomas A Hope
  • Simron Singh
  • Riad Salem
  • David C Metz
  • Boris G Naraev
  • Diane L Reidy-Lagunes
  • James R Howe
  • Rodney F Pommier
  • Yusuf Menda
  • Jennifer A Chan
  • Pancreas.2020 Aug;49(7):863-881. 00006676-202008000-00001. doi: 10.1097/MPA.0000000000001597.

乳酸菌のケラチノサイトに対する創傷治癒、抗炎症、抗病原性、プロテオミクス効果を探る

Exploring the wound healing, anti-inflammatory, anti-pathogenic and proteomic effects of lactic acid bacteria on keratinocytes.
  • Jessica Brandi
  • Samuele Cheri
  • Marcello Manfredi
  • Claudia Di Carlo
  • Virginia Vita Vanella
  • Federica Federici
  • Eleonora Bombiero
  • Alda Bazaj
  • Eleonora Rizzi
  • Laura Manna
  • Giuseppe Cornaglia
  • Umberto Marini
  • Maria Teresa Valenti
  • Emilio Marengo
  • Daniela Cecconi
  • Sci Rep.2020 Jul;10(1):11572. 10.1038/s41598-020-68483-4. doi: 10.1038/s41598-020-68483-4.Epub 2020-07-14.

システマティックレビューの検索ツールとして完全なPICOモデルを使用すると、いくつかのPICO要素の検索結果の再現性が低くなることがわかった

Using the full PICO model as a search tool for systematic reviews resulted in lower recall for some PICO elements.
  • Tove Faber Frandsen
  • Michael Friberg Bruun Nielsen
  • Christina Louise Lindhardt
  • Mette Brandt Eriksen
  • J Clin Epidemiol.2020 Jul;S0895-4356(20)30569-2. doi: 10.1016/j.jclinepi.2020.07.005.Epub 2020-07-14.

難治性そう痒症の治療に対する経鼻的ブトルファノールレスキュー療法。ジョンズ・ホプキンスかゆみクリニックの症例シリーズ

Intranasal Butorphanol Rescue Therapy for the Treatment of Intractable Pruritus: A Case Series from the Johns Hopkins Itch Clinic.
  • Raveena Khanna
  • Christina D Kwon
  • Sagar P Patel
  • Micah Belzberg
  • Kyle A Williams
  • Ramona Khanna
  • Emily Boozalis
  • Shawn G Kwatra
  • J. Am. Acad. Dermatol..2020 Jul;S0190-9622(20)32181-2. doi: 10.1016/j.jaad.2020.07.017.Epub 2020-07-14.

上咽頭がん生存者における性的満足度。率と決定因子

Sexual satisfaction in nasopharyngeal carcinoma survivors: Rates and determinants.
  • Lachlan McDowell
  • Nathaniel So
  • Sareh Keshavarzi
  • Wei Xu
  • Kathy Rock
  • Biu Chan
  • John Waldron
  • Lori J Bernstein
  • Shao Hui Huang
  • Meredith Giuliani
  • Andrew Hope
  • Brian O'Sullivan
  • Scott V Bratman
  • John Cho
  • John Kim
  • Raymond Jang
  • Andrew Bayley
  • Jolie Ringash
  • Oral Oncol..2020 Jul;109:104865. S1368-8375(20)30301-8. doi: 10.1016/j.oraloncology.2020.104865.Epub 2020-07-14.

HIVに感染した成人の結核に対する系統的または試験的な治療

Systematic or Test-Guided Treatment for Tuberculosis in HIV-Infected Adults.
  • François-Xavier Blanc
  • Anani D Badje
  • Maryline Bonnet
  • Delphine Gabillard
  • Eugène Messou
  • Conrad Muzoora
  • Sovannarith Samreth
  • Bang D Nguyen
  • Laurence Borand
  • Anaïs Domergue
  • Delphine Rapoud
  • Naome Natukunda
  • Sopheak Thai
  • Sylvain Juchet
  • Serge P Eholié
  • Stephen D Lawn
  • Serge K Domoua
  • Xavier Anglaret
  • Didier Laureillard
  • N. Engl. J. Med..2020 06;382(25):2397-2410. doi: 10.1056/NEJMoa1910708.

包括的な凝固・線溶機能に基づくセプシス関連播種性血管内凝固の病理学的解明

A Pathological Clarification of Sepsis-Associated Disseminated Intravascular Coagulation Based on Comprehensive Coagulation and Fibrinolysis Function.
  • Tomoko Onishi
  • Keiji Nogami
  • Takashi Ishihara
  • Satoki Inoue
  • Masahiko Kawaguchi
  • Kenji Nishio
  • Hidetada Fukushima
  • Hiroshi Kobayashi
  • Itsuto Amano
  • Toshiya Nishikubo
  • Masaharu Yamasaki
  • Masato Kasahara
  • Midori Shima
  • Thromb. Haemost..2020 Jul;doi: 10.1055/s-0040-1713890.Epub 2020-07-17.

膀胱癌を尿中で非侵襲的に検出するための新しい無細胞単一分子ユニークプライマー拡張リセケンシング(cf-SUPER)技術

A novel cell-free single-molecule unique primer extension resequencing (cf-SUPER) technology for bladder cancer non-invasive detection in urine.
  • Cheng Zhao
  • Yi Pan
  • Yinhuai Wang
  • Yuanwei Li
  • Weiqing Han
  • Li Lu
  • Wei Tang
  • Pei Li
  • Zhenyu Ou
  • Mengda Zhang
  • Zhuang Xiong
  • Ran Xu
  • Qiang Lu
  • Zhenzhou Xu
  • Lin Qi
  • Long Wang
  • Genming Xu
  • Transl Androl Urol.2020 Jun;9(3):1222-1231. tau-09-03-1222. doi: 10.21037/tau-19-774.

インフルエンザウイルス由来の核タンパク質抗原ペプチドをカプセル化したアポフェリチン-ヘマグルチニン・コンジュゲートワクチンは、強化された交差防御をもたらします

An apoferritin-haemagglutinin conjugate vaccine with encapsulated nucleoprotein antigen peptide from influenza virus confers enhanced cross protection.
  • Jiangxue Wei
  • Zhengjun Li
  • Yanli Yang
  • Guanghui Ma
  • Zhiguo Su
  • Songping Zhang
  • Bioconjug. Chem..2020 Jul;doi: 10.1021/acs.bioconjchem.0c00308.Epub 2020-07-17.

多発性硬化症患者と非多発性硬化症患者の認知能力の変化を評価するためのSDTテストと言語流暢性テストの検出可能な最小変化とは?

What Are the Minimal Detectable Changes in SDMT and Verbal Fluency Tests for Assessing Changes in Cognitive Performance in Persons with Multiple Sclerosis and Non-Multiple Sclerosis Controls?
  • Eloi Magnin
  • Yoshimasa Sagawa
  • Thierry Moulin
  • Pierre Decavel
  • Eur. Neurol..2020 Jul;:1-8. 000508607. doi: 10.1159/000508607.Epub 2020-07-07.

ミトコンドリアを標的とした酸化還元GFPは、光力学的治療中に細胞死の決定を分岐させながら、ミトコンドリア酸化の時間と用量に依存した発症と進行を明らかにする

Mitochondria targeted redox GFP reveals time and dose dependent onset and progression of mitochondrial oxidation with diverging cell death decisions during photodynamic therapy.
  • Pramod Darvin
  • Aneesh Chandrasekharan
  • Shankara Narayanan Varadarajan
  • Leena Chandrasekhar
  • Roshan Thomas Maliakkal
  • John Sam S M
  • Shine Varghese Jancy
  • T R Santhoshkumar
  • Photodiagnosis Photodyn Ther.2020 Jul;:101921. S1572-1000(20)30275-1. doi: 10.1016/j.pdpdt.2020.101921.Epub 2020-07-14.

PRRT2イタリア人患者における臨床スペクトルと遺伝子型-フェノタイプの相関

Clinical spectrum and genotype-phenotype correlations in PRRT2 Italian patients.
  • Ganna Balagura
  • Antonella Riva
  • Francesca Marchese
  • Michele Iacomino
  • Francesca Madia
  • Thea Giacomini
  • Maria Margherita Mancardi
  • Elisabetta Amadori
  • Maria Stella Vari
  • Vincenzo Salpietro
  • Angelo Russo
  • Tullio Messana
  • Aglaia Vignoli
  • Valentina Chiesa
  • Lucio Giordano
  • Patrizia Accorsi
  • Lorella Caffi
  • Alessandro Orsini
  • Alice Bonuccelli
  • Margherita Santucci
  • Marilena Vecchi
  • Francesca Vanadia
  • Giuseppe Milito
  • Carlo Fusco
  • Giovanni Cricchiutti
  • Marilisa Carpentieri
  • Lucia Margari
  • Alberto Spalice
  • Francesca Beccaria
  • Fabio Benfenati
  • Federico Zara
  • Pasquale Striano
  • Eur. J. Paediatr. Neurol..2020 Jun;S1090-3798(20)30113-6. doi: 10.1016/j.ejpn.2020.06.005.Epub 2020-06-23.

mTOR 経路を持続的に活性化した新規ヒト骨肉腫細胞株 COS-33 の開発と特性評価

Development and characterization of the novel human osteosarcoma cell line COS-33 with sustained activation of the mTOR pathway.
  • Ashley VanCleave
  • Mykayla Palmer
  • Fang Fang
  • Haydee Torres
  • Tania Rodezno
  • Qilin Li
  • Kirby Fuglsby
  • Claire Evans
  • Yohannes Afeworki
  • Alan Ross
  • Pulivarthi Rao
  • Patricia Leiferman
  • Siyuan Zheng
  • Peter Houghton
  • Jianning Tao
  • Oncotarget.2020 Jul;11(27):2597-2610. 27611. doi: 10.18632/oncotarget.27611.Epub 2020-07-07.

1次元および3次元多核スピンクロスオーバーFe(II)ウレアトリアゾール高分子鎖の振動特性と鎖内協調性の定量化

Vibrational properties of 1D- and 3D polynuclear spin crossover Fe(II) urea-triazoles polymer chains and quantification of intrachain cooperativity.
  • Juliusz Adam Wolny
  • Tim Hochdörffer
  • Sakshath Sadashivaiah
  • Hendrik Auerbach
  • Kevin Jenni
  • Lena Scherthan
  • Li Ai-Min
  • Hans-Christian Wille
  • Eva Rentschler
  • Volker Schünemann
  • Christian Gero Dominik von Malotki
  • J Phys Condens Matter.2020 Jul;doi: 10.1088/1361-648X/aba71d.Epub 2020-07-17.

活性化された好中球を用いた培養後の再生への取り組みについては、様々な情報源から得られたMSCのサイトカイン動態から確認されています

Cytokine physiognomies of MSCs from varied sources confirm the regenerative commitment post-coculture with activated neutrophils.
  • Ahmed Al-Hakami
  • Saad Qaddah Alqhatani
  • Sharaz Shaik
  • Saaed Mohammed Jalfan
  • Mohammed Saad Abu Dhammam
  • Wejdan Asiri
  • Abdullah Misfer Alkahtani
  • Anantharam Devaraj
  • Harish C Chandramoorthy
  • J. Cell. Physiol..2020 May;doi: 10.1002/jcp.29713.Epub 2020-05-09.

ニコチンアミド-ストレプトゾトシンによる糖尿病性腎症に対するCombretum micranthum G. Donの腎保護効果.In-vivoおよびIn-silico実験

Nephroprotective effect of Combretum micranthum G. Don in nicotinamide-streptozotocin induced diabetic nephropathy in rats: In-vivo and In-silico experiments.
  • Mabozou Kpemissi
  • Adrian-Valentin PotÂrniche
  • Povi Lawson-Evi
  • Kossi Metowogo
  • Mamatchi Melila
  • Pare Dramane
  • Marian Taulescu
  • Vivek Chandramohan
  • Doddamavattur Shivalingaiah Suhas
  • Tumbadi Adinarayanashetty Puneeth
  • Vijaya Kumar S
  • Laurian Vlase
  • Sanda Andrei
  • Kwashie Eklu-Gadegbeku
  • Bogdan Sevastre
  • Veeresh P Veerapur
  • J Ethnopharmacol.2020 Jul;:113133. S0378-8741(20)33014-2. doi: 10.1016/j.jep.2020.113133.Epub 2020-07-13.

リアルタイムコヒーレントMIMO受信機を用いた48kmの少数モードファイバ上での弱結合10モード分割多重伝送を実現する

Weakly coupled 10-mode-division multiplexed transmission over 48-km few-mode fibers with real-time coherent MIMO receivers.
  • Shohei Beppu
  • Koji Igarashi
  • Masahiro Kikuta
  • Daiki Soma
  • Tomoyuki Nagai
  • Yasuo Saito
  • Hidenori Takahashi
  • Takehiro Tsuritani
  • Itsuro Morita
  • Masatoshi Suzuki
  • Opt Express.2020 Jun;28(13):19655-19668. 432788. doi: 10.1364/OE.395415.

COVID-19パンデミック時の呼吸器症状を持つ患者の早期管理のための肺超音波検査

Lung ultrasonography for early management of patients with respiratory symptoms during COVID-19 pandemic.
  • Andrea Smargiassi
  • Gino Soldati
  • Alberto Borghetti
  • Giancarlo Scoppettuolo
  • Enrica Tamburrini
  • Antonia Carla Testa
  • Francesca Moro
  • Luigi Natale
  • Anna Rita Larici
  • Danilo Buonsenso
  • Piero Valentini
  • Gaetano Draisci
  • Bruno Antonio Zanfini
  • Maurizio Pompili
  • Giovanni Scambia
  • Antonio Lanzone
  • Francesco Franceschi
  • Gian Ludovico Rapaccini
  • Antonio Gasbarrini
  • Paolo Giorgini
  • Luca Richeldi
  • Libertario Demi
  • Riccardo Inchingolo
  • J Ultrasound.2020 Jul;10.1007/s40477-020-00501-7. doi: 10.1007/s40477-020-00501-7.Epub 2020-07-07.

ルキソリチニブで治療された非定型慢性骨髄性白血病における好中球顆粒球の欠陥遊走と形態異常

Defective migration and dysmorphology of neutrophil granulocytes in atypical chronic myeloid leukemia treated with ruxolitinib.
  • Lea Bornemann
  • Marc Schuster
  • Saskia Schmitz
  • Charlyn Sobczak
  • Clara Bessen
  • Simon F Merz
  • Karl-Heinz Jöckel
  • Thomas Haverkamp
  • Matthias Gunzer
  • Joachim R Göthert
  • BMC Cancer.2020 Jul;20(1):650. 10.1186/s12885-020-07130-7. doi: 10.1186/s12885-020-07130-7.Epub 2020-07-13.

胸部照射および化学療法を受けた被験者と古典的心血管系リスク因子を持たない被験者における心臓虚血のリスク因子としての胸部放射線療法

Thoracic Radiotherapy As A Risk Factor For Heart Ischemia In Subjects Treated With Chest Irradiation And Chemotherapy And Without Classic Cardiovascular RISK Factors.
  • Paola Vallerio
  • Alessandro Maloberti
  • Matteo Palazzini
  • Lucia Occhi
  • Alessio Peretti
  • Stefano Nava
  • Francesco Soriano
  • Francesco Musca
  • Benedetta DE Chiara
  • Oriana Belli
  • Antonella Moreo
  • Irma Bisceglia
  • Chiara Lestuzzi
  • Cristina Giannattasio
  • Radiother Oncol.2020 Jul;S0167-8140(20)30397-2. doi: 10.1016/j.radonc.2020.07.004.Epub 2020-07-14.

西アフリカの自然発酵穀物および乳製品から分離したサッカロミセス・セレビシエとクルイベロミセス・マルキシアヌスのプロバイオティクスの潜在能力

Probiotic potential of Saccharomycescerevisiae and Kluyveromycesmarxianusisolated fromWest Africanspontaneously fermentedcereal and milk products.
  • Grace Adzo Motey
  • Pernille Greve Johansen
  • James Owusu-Kwarteng
  • Linda Aurelia Ofori
  • Kwasi Obiri-Danso
  • Henrik Siegumfeldt
  • Nadja Larsen
  • Lene Jespersen
  • Yeast.2020 Jul;doi: 10.1002/yea.3513.Epub 2020-07-17.

ピペリジン誘導体によるヒトリンパ系フィラリア寄生虫のインビトロアポトーシス効果とチミジン反転試験

In vitro apoptotic effect on human lymphatic filarial parasite by piperidine derivatives and thymidine reversal study.
  • Priyanka S Bhoj
  • Sahitya Rao
  • Sandeep P Bahekar
  • Nikita R Agrawal
  • Namdev S Togre
  • Richa Sharma
  • Kalyan Goswami
  • Hemant S Chandak
  • Mandakini B Patil
  • Parasitol. Res..2020 Jan;119(1):165-175. 10.1007/s00436-019-06492-7. doi: 10.1007/s00436-019-06492-7.Epub 2019-12-05.

中等度の心血管リスクを有する2型糖尿病患者におけるメトホルミン治療の追加療法:全国規模の研究

Add-on therapy in metformin-treated patients with type 2 diabetes at moderate cardiovascular risk: a nationwide study.
  • David Thein
  • Mia Nielsen Christiansen
  • Ulrik Madvig Mogensen
  • Johan Skov Bundgaard
  • Rasmus Rørth
  • Christian Madelaire
  • Emil Loldrup Fosbøl
  • Morten Schou
  • Christian Torp-Pedersen
  • Gunnar Gislason
  • Lars Køber
  • Søren Lund Kristensen
  • Cardiovasc Diabetol.2020 Jul;19(1):107. 10.1186/s12933-020-01078-5. doi: 10.1186/s12933-020-01078-5.Epub 2020-07-06.

ADAMTS13とVWF活性は、aTTP患者における個別化されたカプラシズマブ治療の指針となる

ADAMTS13 and VWF activities guide individualized caplacizumab treatment in patients with aTTP.
  • Linus A Völker
  • Jessica Kaufeld
  • Wolfgang Miesbach
  • Sebastian Brähler
  • Martin Reinhardt
  • Lucas Kühne
  • Anja Mühlfeld
  • Adrian Schreiber
  • Jens Gaedeke
  • Markus Tölle
  • Wolfram J Jabs
  • Fedai Özcan
  • Silke Markau
  • Matthias Girndt
  • Frederic Bauer
  • Timm H Westhoff
  • Helmut Felten
  • Martin Hausberg
  • Marcus Brand
  • Jens Gerth
  • Markus Bieringer
  • Martin Bommer
  • Stefan Zschiedrich
  • Johanna Schneider
  • Saban Elitok
  • Alexander Gawlik
  • Anja Gäckler
  • Andreas Kribben
  • Vedat Schwenger
  • Ulf Schoenermarck
  • Maximilian Roeder
  • Jörg Radermacher
  • Jörn Bramstedt
  • Anke Morgner
  • Regina Herbst
  • Ana Harth
  • Sebastian A Potthoff
  • Charis von Auer
  • Ralph Wendt
  • Hildegard Christ
  • Paul T Brinkkoetter
  • Jan Menne
  • Blood Adv.2020 Jul;4(13):3093-3101. 461269. doi: 10.1182/bloodadvances.2020001987.

深い学習によって変更される教授学習ベースの最適化の下のプレハブの建物のプロジェクトのためのリスク管理システムそして理性的な意思決定

Risk management system and intelligent decision-making for prefabricated building project under deep learning modified teaching-learning-based optimization.
  • Huazan Liu
  • Yukang He
  • Qichao Hu
  • Jianfei Guo
  • Lan Luo
  • PLoS ONE.2020;15(7):e0235980. PONE-D-20-09483. doi: 10.1371/journal.pone.0235980.Epub 2020-07-17.

光ファイバ通信のための小型で効率的なOバンドビスマス添加リン酸塩ファイバ増幅器

Compact and efficient O-band bismuth-doped phosphosilicate fiber amplifier for fiber-optic communications.
  • Sergei V Firstov
  • Aleksandr M Khegai
  • Alexander V Kharakhordin
  • Sergey V Alyshev
  • Elena G Firstova
  • Yan J Ososkov
  • Mikhail A Melkumov
  • Lyudmila D Iskhakova
  • Elena B Evlampieva
  • Alexey S Lobanov
  • Mikhail V Yashkov
  • Alexey N Guryanov
  • Sci Rep.2020 Jul;10(1):11347. 10.1038/s41598-020-68243-4. doi: 10.1038/s41598-020-68243-4.Epub 2020-07-09.

ペルー、アンカシュ地方の農村部で発生する新しい病原体、Bartonella ancashensisの全ゲノム解析

Whole-Genome Analysis of Bartonella ancashensis, a Novel Pathogen Causing Verruga Peruana, Rural Ancash Region, Peru.
  • Kristin E Mullins
  • Jun Hang
  • Robert J Clifford
  • Fatma Onmus-Leone
  • Yu Yang
  • Ju Jiang
  • Mariana Leguia
  • Matthew R Kasper
  • Ciro Maguina
  • Emil P Lesho
  • Richard G Jarman
  • Allen Richards
  • David Blazes
  • Emerging Infect. Dis..2017 03;23(3):430-438. doi: 10.3201/eid2303.161476.

農家および食肉処理場従事者の糞便レジストームおよびマイクロバイオームの記述と決定因子。メタゲノムワイドな横断的研究

Description and determinants of the faecal resistome and microbiome of farmers and slaughterhouse workers: A metagenome-wide cross-sectional study.
  • Liese Van Gompel
  • Roosmarijn E C Luiken
  • Rasmus B Hansen
  • Patrick Munk
  • Martijn Bouwknegt
  • Lourens Heres
  • Gerdit D Greve
  • Peter Scherpenisse
  • Betty G M Jongerius-Gortemaker
  • Monique H G Tersteeg-Zijderveld
  • Silvia García-Cobos
  • Wietske Dohmen
  • Alejandro Dorado-García
  • Jaap A Wagenaar
  • Bert A P Urlings
  • Frank M Aarestrup
  • Dik J Mevius
  • Dick J J Heederik
  • Heike Schmitt
  • Alex Bossers
  • Lidwien A M Smit
  • Environ Int.2020 Jul;143:105939. S0160-4120(20)31894-8. doi: 10.1016/j.envint.2020.105939.Epub 2020-07-14.

コロナウイルス病アウトブレイク時の接触者追跡、韓国、2020年

Contact Tracing during Coronavirus Disease Outbreak, South Korea, 2020.
  • Young Joon Park
  • Young June Choe
  • Ok Park
  • Shin Young Park
  • Young-Man Kim
  • Jieun Kim
  • Sanghui Kweon
  • Yeonhee Woo
  • Jin Gwack
  • Seong Sun Kim
  • Jin Lee
  • Junghee Hyun
  • Boyeong Ryu
  • Yoon Suk Jang
  • Hwami Kim
  • Seung Hwan Shin
  • Seonju Yi
  • Sangeun Lee
  • Hee Kyoung Kim
  • Hyeyoung Lee
  • Yeowon Jin
  • Eunmi Park
  • Seung Woo Choi
  • Miyoung Kim
  • Jeongsuk Song
  • Si Won Choi
  • Dongwook Kim
  • Byoung-Hak Jeon
  • Hyosoon Yoo
  • Eun Kyeong Jeong
  • Emerging Infect. Dis..2020 Jul;26(10). doi: 10.3201/eid2610.201315.Epub 2020-07-16.

NMDARアンタゴニストの長期使用は、一酸化窒素還元誘導GABA作動性阻害を介して神経障害性疼痛における鎮痛耐性を開発する

Prolonged Use of NMDAR Antagonist Develops Analgesic Tolerance in Neuropathic Pain via Nitric Oxide Reduction-Induced GABAergic Disinhibition.
  • Jun Li
  • Lin Zhang
  • Chu Xu
  • Yu-Hui Lin
  • Yu Zhang
  • Hai-Yin Wu
  • Lei Chang
  • Ying-Dong Zhang
  • Chun-Xia Luo
  • Fei Li
  • Dong-Ya Zhu
  • Neurotherapeutics.2020 Jul;10.1007/s13311-020-00883-w. doi: 10.1007/s13311-020-00883-w.Epub 2020-07-06.

調節性ペプチドとシステムバイオロジー。トランスレーショナル、リバーストランスレーショナル神経内分泌学の新時代

Regulatory peptides and systems biology: A new era of translational and reverse-translational neuroendocrinology.
  • Lee E Eiden
  • Andrew L Gundlach
  • Valery Grinevich
  • Mary R Lee
  • André S Mecawi
  • Duan Chen
  • Ruud M Buijs
  • Vito S Hernandez
  • Germán Fajardo-Dolci
  • Limei Zhang
  • J. Neuroendocrinol..2020 May;32(5):e12844. doi: 10.1111/jne.12844.Epub 2020-04-19.

システマティックレビューでは、未熟な永久歯における一回訪問再灌流歯内療法による治療が重要な利益をもたらすという十分なエビデンスは得られていない

Systematic review does not provide sufficient evidence that there are important benefits from single-visit revascularization endodontic procedures in immature permanent teeth.
  • Romina Brignardello-Petersen
  • J Am Dent Assoc.2020 07;151(7):e55. S0002-8177(20)30074-X. doi: 10.1016/j.adaj.2020.01.028.Epub 2020-05-05.

慢性脳卒中生存者におけるロボットバランスおよびコアスタビリティトレーニング後の動的安定性および体幹制御の改善。パイロット研究

Dynamic Stability and Trunk Control Improvements Following Robotic Balance and Core Stability Training in Chronic Stroke Survivors: A Pilot Study.
  • Alice De Luca
  • Valentina Squeri
  • Laura M Barone
  • Honorè Vernetti Mansin
  • Serena Ricci
  • Ivano Pisu
  • Cinzia Cassiano
  • Cristina Capra
  • Carmelo Lentino
  • Lorenzo De Michieli
  • Carlo A Sanfilippo
  • Jody A Saglia
  • Giovanni A Checchia
  • Front Neurol.2020;11:494. doi: 10.3389/fneur.2020.00494.Epub 2020-06-17.

メタボリックシンドロームを持つ成人のグルコース制御と脂質代謝に対するタラ蛋白加水分解物の低用量のサプリメント。無作為化二重盲検試験

Supplementation with Low Doses of a Cod Protein Hydrolysate on Glucose Regulation and Lipid Metabolism in Adults with Metabolic Syndrome: A Randomized, Double-Blind Study.
  • Caroline Jensen
  • Hanna Fjeldheim Dale
  • Trygve Hausken
  • Jan Gunnar Hatlebakk
  • Ingeborg Brønstad
  • Gülen Arslan Lied
  • Dag Arne Lihaug Hoff
  • Nutrients.2020 Jul;12(7). E1991. doi: 10.3390/nu12071991.Epub 2020-07-04.

クロージング・ザ・ギャップ:適応性のあるレーザー応答性銅(II)および感度の高い銀(I)錯体における3つの異性体、-ジテトラゾリメタン配位子の合成とその配位能力

Closing the Gap: Synthesis of Three Isomeric ,-Ditetrazolymethane Ligands and Their Coordination Proficiency in Adaptable Laser Responsive Copper(II) and Sensitive Silver(I) Complexes.
  • Maximilian H H Wurzenberger
  • Vanessa Braun
  • Marcus Lommel
  • Thomas M Klapötke
  • Jörg Stierstorfer
  • Inorg Chem.2020 Jul;doi: 10.1021/acs.inorgchem.0c01403.Epub 2020-07-13.

シミュレーションに基づく教育介入の前後における医療従事者の認知的負荷とPPEの着用・脱着におけるパフォーマンス、およびCOVID-19パンデミック時のバイオセーフティへの影響

Cognitive load and performance of health care professionals in donning and doffing PPE before and after a simulation-based educational intervention and its implications during the COVID-19 pandemic for biosafety.
  • Diego Andrés Díaz-Guio
  • Alejandra Ricardo-Zapata
  • Jeniffer Ospina-Velez
  • Gabriel Gómez-Candamil
  • Santiago Mora-Martinez
  • Alfonso J Rodriguez-Morales
  • Infez Med.2020 Jun;28(suppl 1):111-117.

テノフォビル含有抗レトロウイルス剤併用療法の導入に伴うHIV/B型肝炎ウイルス感染症における全死因死亡リスクおよび肝関連死亡リスクの低下

Decreased All-Cause and Liver-Related Mortality Risk in HIV/Hepatitis B Virus Coinfection Coinciding With the Introduction of Tenofovir-Containing Combination Antiretroviral Therapy.
  • Berend J van Welzen
  • Colette Smit
  • Anders Boyd
  • Faydra I Lieveld
  • Tania Mudrikova
  • Peter Reiss
  • Annemarie E Brouwer
  • Andy I M Hoepelman
  • Joop E Arends
  • Open Forum Infect Dis.2020 Jul;7(7):ofaa226. ofaa226. doi: 10.1093/ofid/ofaa226.Epub 2020-06-25.

世界中のシャープシューターは同じEPG波形を生成するのか?昆虫の種類に応じて、その種類が異なることがわかっていますが、このような違いはありません

Do Sharpshooters From Around the World Produce the Same EPG Waveforms? Comparison of Waveform Libraries From Xylella fastidiosa (Xanthomonadales: Xanthomonadaceae) Vectors Kolla paulula (Hemiptera: Cicadellidae) From Taiwan and Graphocephala atropunctata From California.
  • Elaine A Backus
  • Hsien-Tzung Shih
  • J. Insect Sci..2020 Jul;20(4). 7. doi: 10.1093/jisesa/ieaa056.

ラットの歯の漂白による歯髄損傷を最小限に抑えるための生理活性ガラスセラミックを含む実験用ゲル

Experimental gel containing bioactive glass-ceramic to minimize the pulp damage caused by dental bleaching in rats.
  • Marina Carminatti
  • Francine Benetti
  • Renato Luiz Siqueira
  • Edgar Dutra Zanotto
  • André Luiz Fraga Briso
  • Antônio Hernandes Chaves-Neto
  • Luciano Tavares Angelo Cintra
  • J Appl Oral Sci.2020;28:e20190384. S1678-77572020000100449. doi: 10.1590/1678-7757-2019-0384.Epub 2020-06-08.

von Willebrand Factorは、強力なP2Y12拮抗薬で治療されたACS患者の死亡率を予測し、Aptamer BT200によってEx Vivoで阻害される

von Willebrand Factor Predicts Mortality in ACS Patients Treated with Potent P2Y12 Antagonists and is Inhibited by Aptamer BT200 Ex Vivo.
  • Katarina D Kovacevic
  • Bernd Jilma
  • Shuhao Zhu
  • James C Gilbert
  • Max-Paul Winter
  • Aurel Toma
  • Christian Hengstenberg
  • Irene Lang
  • Jacek Kubica
  • Jolanta M Siller-Matula
  • Thromb. Haemost..2020 Jul;doi: 10.1055/s-0040-1713888.Epub 2020-07-17.

24時間シフトなしの研修医スケジュールが患者の安全性に及ぼす影響

Effect on Patient Safety of a Resident Physician Schedule without 24-Hour Shifts.
  • Christopher P Landrigan
  • Shadab A Rahman
  • Jason P Sullivan
  • Eric Vittinghoff
  • Laura K Barger
  • Amy L Sanderson
  • Kenneth P Wright
  • Conor S O'Brien
  • Salim Qadri
  • Melissa A St Hilaire
  • Ann C Halbower
  • Jeffrey L Segar
  • John K McGuire
  • Michael V Vitiello
  • Horacio O de la Iglesia
  • Sue E Poynter
  • Pearl L Yu
  • Phyllis C Zee
  • Steven W Lockley
  • Katie L Stone
  • Charles A Czeisler
  • N. Engl. J. Med..2020 06;382(26):2514-2523. doi: 10.1056/NEJMoa1900669.

スリランカの三次医療施設に通う子どもたちにおける片頭痛、注意欠陥多動性障害、スクリーンタイム:それらは関連しているか?

Migraine, attention deficit hyperactivity disorder and screen time in children attending a Sri Lankan tertiary care facility: are they associated?
  • Udena Ruwindu Attygalle
  • Gemunu Hewawitharana
  • Champa Jayalakshmie Wijesinghe
  • BMC Neurol.2020 Jul;20(1):275. 10.1186/s12883-020-01855-5. doi: 10.1186/s12883-020-01855-5.Epub 2020-07-08.

2'-デオキシ-2'-β-フルオロ-4'-アジドシチジン(FNC)のHIV-1予防効果が長期間持続する抗レトロウイルス薬としての有効性のメカニズムを明らかにした

Mechanistic insight into antiretroviral potency of 2'-deoxy-2'-β-fluoro-4'-azidocytidine (FNC) with a long-lasting effect on HIV-1 prevention.
  • Li Sun
  • Youmei Peng
  • Wenquan Yu
  • Yan Zhang
  • Lan Liang
  • Chuanjun Song
  • Jiao Hou
  • Yan Qiao
  • Qingduan Wang
  • Jingyu Chen
  • Mengli Wu
  • Dongwei Zhang
  • Ertong Li
  • Zhifu Han
  • Qingxia Zhao
  • Xia Jin
  • Bailing Zhang
  • Zhiwei Huang
  • Jijie Chai
  • Jian-Hua Wang
  • Junbiao Chang
  • J. Med. Chem..2020 Jul;doi: 10.1021/acs.jmedchem.0c00940.Epub 2020-07-17.

不顕性糖尿病関連心筋症における心臓の収縮期および拡張期機能に対する心臓の形状、微小循環、組織特性の複合効果

The combined effects of cardiac geometry, microcirculation, and tissue characteristics on cardiac systolic and diastolic function in subclinical diabetes mellitus-related cardiomyopathy.
  • Li Jiang
  • Jin Wang
  • Xi Liu
  • Zhen-Lin Li
  • Chun-Chao Xia
  • Lin-Jun Xie
  • Yue Gao
  • Meng-Ting Shen
  • Pei-Lun Han
  • Ying-Kun Guo
  • Zhi-Gang Yang
  • Int. J. Cardiol..2020 Jul;S0167-5273(20)33461-6. doi: 10.1016/j.ijcard.2020.07.013.Epub 2020-07-14.

HER2 陽性転移性乳癌および脳転移患者におけるトラスツズマブ・エムタンシン(T-DM1):単群第 IIIb 相臨床試験 KAMILLA のコホート 1 の探索的最終解析

Trastuzumab emtansine (T-DM1) in patients with HER2-positive metastatic breast cancer and brain metastases: exploratory final analysis of cohort 1 from KAMILLA, a single-arm phase IIIb clinical trial.
  • F Montemurro
  • S Delaloge
  • C H Barrios
  • R Wuerstlein
  • A Anton
  • E Brain
  • T Hatschek
  • C M Kelly
  • C Peña-Murillo
  • M Yilmaz
  • M Donica
  • P Ellis
  • Ann. Oncol..2020 Jul;S0923-7534(20)39930-0. doi: 10.1016/j.annonc.2020.06.020.Epub 2020-07-04.

滑膜細胞を標的とした治療は、関節炎の逆転においてTNF阻害との相乗効果を発揮します

Synoviocyte-targeted therapy synergizes with TNF inhibition in arthritis reversal.
  • Mattias N D Svensson
  • Martina Zoccheddu
  • Shen Yang
  • Gyrid Nygaard
  • Christian Secchi
  • Karen M Doody
  • Kamil Slowikowski
  • Fumitaka Mizoguchi
  • Frances Humby
  • Rebecca Hands
  • Eugenio Santelli
  • Cristiano Sacchetti
  • Kuninobu Wakabayashi
  • Dennis J Wu
  • Christopher Barback
  • Rizi Ai
  • Wei Wang
  • Gary P Sims
  • Piotr Mydel
  • Tsuyoshi Kasama
  • David L Boyle
  • Francesco Galimi
  • David Vera
  • Michel L Tremblay
  • Soumya Raychaudhuri
  • Michael B Brenner
  • Gary S Firestein
  • Costantino Pitzalis
  • Anna-Karin H Ekwall
  • Stephanie M Stanford
  • Nunzio Bottini
  • Sci Adv.2020 Jun;6(26):eaba4353. aba4353. doi: 10.1126/sciadv.aba4353.Epub 2020-06-26.

非治癒的内視鏡的粘膜下層剥離術後の早期胃癌の予後には、高リスクの併存疾患が影響している:レトロスペクティブ研究

High-risk comorbidity influences prognosis in early gastric cancer after non-curative endoscopic submucosal dissection: a retrospective study.
  • Naoto Iwai
  • Osamu Dohi
  • Yuji Naito
  • Yutaka Inada
  • Ken Inoue
  • Tetsuya Okayama
  • Naohisa Yoshida
  • Kazuhiro Katada
  • Kazuhiro Kamada
  • Kazuhiko Uchiyama
  • Takeshi Ishikawa
  • Tomohisa Takagi
  • Hideyuki Konishi
  • Yoshito Itoh
  • Dig Dis.2020 Jul;000510115. doi: 10.1159/000510115.Epub 2020-07-14.

3種類の異なるナノコンポジットと複合材料/エナメルおよび複合材料/セメント界面の表面粗さに及ぼす仕上げおよび研磨順序の影響

The Effect of Finishing and Polishing Sequences on The Surface Roughness of Three Different Nanocomposites and Composite/Enamel and Composite/Cementum Interfaces.
  • Ksenia Babina
  • Maria Polyakova
  • Inna Sokhova
  • Vladlena Doroshina
  • Marianna Arakelyan
  • Nina Novozhilova
  • Nanomaterials (Basel).2020 Jul;10(7). E1339. doi: 10.3390/nano10071339.Epub 2020-07-09.

GLP-1/GLP-1R シグナルは、フォークヘッドボックスタンパクO1リン酸化部位の修飾により、卵巣PCOS関連顆粒膜細胞の増殖と抗アポトーシスを制御している

GLP-1/GLP-1R Signaling Regulates Ovarian PCOS-Associated Granulosa Cells Proliferation and Antiapoptosis by Modification of Forkhead Box Protein O1 Phosphorylation Sites.
  • Zhihua Sun
  • Peiyi Li
  • Xiao Wang
  • Shuchang Lai
  • Hong Qiu
  • Zhi Chen
  • Shidi Hu
  • Jie Yao
  • Jie Shen
  • Int J Endocrinol.2020;2020:1484321. doi: 10.1155/2020/1484321.Epub 2020-06-19.

敷設鶏の卵のパフォーマンス、卵の質、血清および卵黄脂質、抗酸化状態、鉄蓄積に対する無機鉄と有機鉄の置き換えの効果

Effects of Replacing Inorganic with Organic Iron on Performance, Egg Quality, Serum and Egg Yolk Lipids, Antioxidant Status, and Iron Accumulation in Eggs of Laying Hens.
  • Sima Sarlak
  • Sayed Ali Tabeidian
  • Majid Toghyani
  • Amir Davar Foroozandeh Shahraki
  • Mohammad Goli
  • Mahmood Habibian
  • Biol Trace Elem Res.2020 Jul;10.1007/s12011-020-02284-8. doi: 10.1007/s12011-020-02284-8.Epub 2020-07-14.

炭水化物幼虫抗原(CarLA)に対する唾液抗体と健康状態およびオンタリオ州の放牧条件下でのヒツジの消化管線虫寄生との相関

Correlation of salivary antibody to carbohydrate larval antigen (CarLA) with health and gastrointestinal nematode parasitism in sheep under Ontario grazing conditions.
  • Emma A Borkowski
  • Jacob Avula
  • Niel A Karrow
  • Paula I Menzies
  • William Sears
  • Elizabeth M Redman
  • Brandon N Lillie
  • John S Gilleard
  • Andrew S Peregrine
  • Vet. Parasitol..2020 Jul;283:109183. S0304-4017(20)30163-1. doi: 10.1016/j.vetpar.2020.109183.Epub 2020-07-07.

持続的な外傷後頭痛:偏頭痛ループかどうか?前臨床のエビデンス

Persistent post-traumatic headache: a migrainous loop or not? The preclinical evidence.
  • Silvia Benemei
  • Alejandro Labastida-Ramírez
  • Ekaterina Abramova
  • Nicoletta Brunelli
  • Edoardo Caronna
  • Paola Diana
  • Roman Gapeshin
  • Maxi Dana Hofacker
  • Ilaria Maestrini
  • Enrique Martínez Pías
  • Petr Mikulenka
  • Olga Tikhonova
  • Paolo Martelletti
  • Antoinette MaassenVanDenBrink
  • J Headache Pain.2020 Jul;21(1):90. 10.1186/s10194-020-01135-0. doi: 10.1186/s10194-020-01135-0.Epub 2020-07-14.

ラテンアメリカから分離された MRSA 単離株における不均一なバンコマイシン中間耐性の検出

Detection of heterogeneous vancomycin intermediate resistance in MRSA isolates from Latin America.
  • Betsy E Castro
  • Maritza Berrio
  • Monica L Vargas
  • Lina P Carvajal
  • Lina V Millan
  • Rafael Rios
  • Angie K Hernandez
  • Sandra Rincon
  • Paola Cubides
  • Erika Forero
  • An Dinh
  • Carlos Seas
  • Jose M Munita
  • Cesar A Arias
  • Jinnethe Reyes
  • Lorena Diaz
  • J. Antimicrob. Chemother..2020 Jun;dkaa221. doi: 10.1093/jac/dkaa221.Epub 2020-06-20.

ブラジル南部の大学教育病院の出生前診療所で治療を受けた急性トキソプラズマ症が疑われる妊婦を対象としたプロスペクティブ評価

Prospective evalution of pregnant women with suspected acute toxoplasmosis treated in a reference prenatal care clinic at a university teaching hospital in Southern Brazil.
  • Fernanda Ferreira Evangelista
  • Francini Martini Mantelo
  • Keller Karla de Lima
  • Ariella Andrade Marchioro
  • Lucimara Fátima Beletini
  • Amanda Hinobu de Souza
  • Priscila Laet Santana
  • Cristiane de Oliveira Riedo
  • Lourenço Tsunetomi Higa
  • Ana Lúcia Falavigna Guilherme
  • Rev. Inst. Med. Trop. Sao Paulo.2020;62:e46. S0036-46652020000100224. doi: 10.1590/s1678-9946202062046.Epub 2020-07-13.

幼い子供や母親のビリビリ症をなくすための迅速で信頼性の高いイージーユーズダイアグノロジー。freeBILyプロジェクトの紹介

Fast and reliable easy-to-use-diagnostics for eliminating bilharzia in young children and mothers: An introduction to the freeBILy project.
  • Pytsje T Hoekstra
  • Norbert G Schwarz
  • Ayola A Adegnika
  • Mala Rakoto Andrianarivelo
  • Paul L A M Corstjens
  • Rivo A Rakotoarivelo
  • Raphaël Rakotozandrindrainy
  • Elisa Sicuri
  • Andrea Kreidenweiss
  • Govert J van Dam
  • Acta Trop..2020 Jul;:105631. S0001-706X(20)30111-X. doi: 10.1016/j.actatropica.2020.105631.Epub 2020-07-14.

ミトコンドリアを標的としたコエンザイムQペプトイドは、スーパーオキシドジスムターゼを誘導し、植物細胞の塩ストレスを緩和する

A mitochondria-targeted coenzyme Q peptoid induces superoxide dismutase and alleviates salinity stress in plant cells.
  • Kinfemichael Geressu Asfaw
  • Qiong Liu
  • Xiaolu Xu
  • Christina Manz
  • Sabine Purper
  • Rose Eghbalian
  • Stephan W Münch
  • Ilona Wehl
  • Stefan Bräse
  • Elisabeth Eiche
  • Bettina Hause
  • Ivan Bogeski
  • Ute Schepers
  • Michael Riemann
  • Peter Nick
  • Sci Rep.2020 Jul;10(1):11563. 10.1038/s41598-020-68491-4. doi: 10.1038/s41598-020-68491-4.Epub 2020-07-14.

3次元有限要素モデルを用いたバルクフィルフローレジンの収縮とファイバーブラッググレーティング測定によるキャリブレーション

Bulk Fill flow resin contraction using 3D finite element model and calibration by Fiber Bragg Grating measurement.
  • Claudio Antunes Junior
  • Emílio Graciliano Ferreira Mercuri
  • Ana Paula Gebert de Oliveira Franco
  • Manoella Costa
  • Leandro Zen Karam
  • Hypolito José Kalinowski
  • Osnara Maria Mongruel Gomes
  • Comput Methods Biomech Biomed Engin.2020 Jul;:1-11. doi: 10.1080/10255842.2020.1789607.Epub 2020-07-13.

高脂肪食/ストレプトゾトシン誘発糖尿病ラットにおけるアルテミシア抽出物の肝障害に対するメトホルミンと比較した保護効果

Protective effects of Artemisia judaica extract compared to metformin against hepatorenal injury in high-fat diet/streptozotocine-induced diabetic rats.
  • Gadah Albasher
  • Mona Alwahaibi
  • Mohamed M Abdel-Daim
  • Saad Alkahtani
  • Rafa Almeer
  • Environ Sci Pollut Res Int.2020 Jul;10.1007/s11356-020-09997-2. doi: 10.1007/s11356-020-09997-2.Epub 2020-07-14.

チェコ共和国における大腸がん検診の経験:早期発見と臨床転帰の改善

The experience with colorectal cancer screening in the Czech Republic: the detection at earlier stages and improved clinical outcomes.
  • J Kral
  • V Kojecky
  • M Stepan
  • M Vladarova
  • O Zela
  • J Knot
  • M Jakovljevic
  • Z Kralova
  • R Buresova
  • T Grega
  • D Bauman
  • J Kotyza
  • R Stepanova
  • T Hucl
  • P Vodicka
  • L Vodickova
  • J Spicak
  • Public Health.2020 Jul;185:153-158. S0033-3506(20)30183-9. doi: 10.1016/j.puhe.2020.05.021.Epub 2020-07-04.

重くドープされたPbSコロイダル量子ドットからの赤外電気通信帯域における単一励起子利得と刺激された発光

Single-Exciton Gain and Stimulated Emission across the Infrared Telecom Band from Robust Heavily-doped PbS Colloidal Quantum Dots.
  • Sotirios Christodoulou
  • Iñigo Ramiro
  • Andreas Othonos
  • Alberto Figueroba
  • Mariona Dalmases
  • Onur Ozdemir
  • Santanu Pradhan
  • Grigorios Itskos
  • Gerasimos Konstantatos
  • Nano Lett..2020 Jul;doi: 10.1021/acs.nanolett.0c01859.Epub 2020-07-14.

インターロイキン-35の前処理は、炎症、アポトーシス、線維化反応を抑制することで、リポ多糖類誘発性心臓障害を減衰させる

Interleukin-35 pretreatment attenuates lipopolysaccharide-induced heart injury by inhibition of inflammation, apoptosis and fibrotic reactions.
  • Huan Hu
  • Yang Fu
  • Meng Li
  • Huasong Xia
  • Yue Liu
  • Xiaopei Sun
  • Yang Hu
  • Fulin Song
  • Xiaoshu Cheng
  • Ping Li
  • Yanqing Wu
  • Int. Immunopharmacol..2020 Jul;86:106725. S1567-5769(20)30694-9. doi: 10.1016/j.intimp.2020.106725.Epub 2020-07-14.

慢性閉塞性肺疾患増悪時の抗生物質処方のためのプロカルシトニン。システマティックレビュー、メタアナリシス、臨床的観点からの検討

Procalcitonin for Antibiotic Prescription in Chronic Obstructive Pulmonary Disease Exacerbations: Systematic Review, Meta-Analysis, and Clinical Perspective.
  • Ken Chen
  • Katherine A Pleasants
  • Roy A Pleasants
  • Tatsiana Beiko
  • Ronald G Washburn
  • Zhiheng Yu
  • Suodi Zhai
  • M Bradley Drummond
  • Pulm Ther.2020 Jul;10.1007/s41030-020-00123-8. doi: 10.1007/s41030-020-00123-8.Epub 2020-07-16.

要旨:重篤なメチシリン耐性黄色ブドウ球菌感染症に対するバンコマイシンの治療的モニタリング.米国保健システム薬剤師会、米国感染症学会、小児感染症学会、感染症薬剤師会の改訂コンセンサスガイドラインとレビュー

Executive Summary: Therapeutic Monitoring of Vancomycin for Serious Methicillin-Resistant Staphylococcus aureus Infections: A Revised Consensus Guideline and Review of the American Society of Health-System Pharmacists, the Infectious Diseases Society of America, the Pediatric Infectious Diseases Society, and the Society of Infectious Diseases Pharmacists.
  • Michael J Rybak
  • Jennifer Le
  • Thomas Lodise
  • Donald Levine
  • John Bradley
  • Catherine Liu
  • Bruce Mueller
  • Manjunath Pai
  • Annie Wong-Beringer
  • John C Rotschafer
  • Keith Rodvold
  • Holly D Maples
  • Benjamin M Lomaestro
  • J Pediatric Infect Dis Soc.2020 07;9(3):281-284. 5871024. doi: 10.1093/jpids/piaa057.

LAMA、LABA、およびICSにナイーブなCOPD患者における第一ラインの維持治療としてのチオトロピウム/オロダテロールと比較した有効性。4つの臨床試験のプール解析

Efficacy of Tiotropium/Olodaterol Compared with Tiotropium as a First-Line Maintenance Treatment in Patients with COPD Who Are Naïve to LAMA, LABA and ICS: Pooled Analysis of Four Clinical Trials.
  • Roland Buhl
  • Alberto de la Hoz
  • Wenqiong Xue
  • Dave Singh
  • Gary T Ferguson
  • Adv Ther.2020 Jul;10.1007/s12325-020-01411-0. doi: 10.1007/s12325-020-01411-0.Epub 2020-07-15.

去勢抵抗性前立腺癌が急速に進行した後、骨盤リンパ節転移を伴う肥大化した前立腺癌の管理に成功した:文献のレビューを含む症例報告

Successful management of prostate cancer with bulky pelvic lymph node metastases after rapid development of castration-resistant prostate cancer: a case report with review of the literature.
  • Lixin Mai
  • Yonghong Li
  • Ping Yang
  • Zitong Zhang
  • Jianhua Wu
  • Fangjian Zhou
  • Yang Liu
  • Liru He
  • Transl Androl Urol.2020 Jun;9(3):1428-1436. tau-09-03-1428. doi: 10.21037/tau-20-725.

高気圧酸素を用いた健康な高齢者の認知機能強化:無作為化比較試験

Cognitive enhancement of healthy older adults using hyperbaric oxygen: a randomized controlled trial.
  • Hadanny Amir
  • Daniel-Kotovsky Malka
  • Suzin Gil
  • Boussi-Gross Rahav
  • Catalogna Merav
  • Dagan Kobi
  • Hachmo Yafit
  • Abu Hamed Ramzia
  • Sasson Efrat
  • Fishlev Gregory
  • Lang Erez
  • Polak Nir
  • Doenyas Keren
  • Friedman Mony
  • Tal Sigal
  • Zemel Yonatan
  • Bechor Yair
  • Efrati Shai
  • Aging (Albany NY).2020 Jun;12. 103571. doi: 10.18632/aging.103571.Epub 2020-06-26.

MUTZ-3由来のランゲルハンス細胞を組み込んだ再建ヒト皮膚で試験したチタン塩は、感作性というよりはむしろ刺激性を示しています

Titanium salts tested in reconstructed human skin with integrated MUTZ-3 derived Langerhans cells show an irritant rather than a sensitizing potential.
  • Charlotte T Rodrigues Neves
  • Sander W Spiekstra
  • Niels P J de Graaf
  • Thomas Rustemeyer
  • Albert J Feilzer
  • Cees J Kleverlaan
  • Susan Gibbs
  • Contact Derm..2020 Jul;doi: 10.1111/cod.13666.Epub 2020-07-16.

新血管性加齢黄斑変性症の治療を受けている中国人患者の健康関連QOLの予測因子:プロスペクティブな縦断的研究

Predictors of health-related quality of life in Chinese patients receiving treatment for neovascular age-related macular degeneration: a prospective longitudinal study.
  • Wei Bian
  • Junli Wan
  • Mingqiong Tan
  • Jun Su
  • Yi Yuan
  • Zonghua Wang
  • Shiying Li
  • BMC Ophthalmol.2020 Jul;20(1):291. 10.1186/s12886-020-01561-3. doi: 10.1186/s12886-020-01561-3.Epub 2020-07-16.

PROMIS 身体機能は効果の大きさが小さく、レガシー股関節特異的な患者報告のアウトカム対策よりも反応性が低い

PROMIS Physical Function Has a Lower Effect Size and is Less Responsive than Legacy Hip Specific Patient Reported Outcomes Measures Following Arthroscopic Hip Surgery.
  • Benedict U Nwachuwu
  • Jonathan Rasio
  • Edward C Beck
  • Kelechi R Okoroha
  • Spencer W Sullivan
  • Eric C Makhni
  • Shane J Nho
  • Arthroscopy.2020 Jul;S0749-8063(20)30601-0. doi: 10.1016/j.arthro.2020.07.008.Epub 2020-07-14.

早期生活の金属曝露は、退行性自閉症スペクトラム障害を持つ子供の細胞の生体エネルギーを異常に調節する

Early life metal exposure dysregulates cellular bioenergetics in children with regressive autism spectrum disorder.
  • Richard E Frye
  • Janet Cakir
  • Shannon Rose
  • Leanna Delhey
  • Sirish C Bennuri
  • Marie Tippett
  • Raymond F Palmer
  • Christine Austin
  • Paul Curtin
  • Manish Arora
  • Transl Psychiatry.2020 Jul;10(1):223. 10.1038/s41398-020-00905-3. doi: 10.1038/s41398-020-00905-3.Epub 2020-07-07.

糖尿病性創傷の多面的な病態生理の管理を目的としたグリコーゲン合成酵素キナーゼ-3β阻害薬としてのロシグリタゾンの仮説検証。糖尿病性創傷の多面的病態管理:インシリコ試験

Hypothesis validation of rosiglitazone a potential inhibitor against glycogen synthase kinase-3β, for the management of multifaceted pathophysiology of the diabetic wound: An insilico study.
  • Tajuddin Mohammed
  • Bharat Kumar Reddy Sanapalli
  • Sayyada Saleha Momina
  • Rakesh Kumar Jat
  • Nagakanyaka Devi Paladugu
  • Med. Hypotheses.2020 Jun;144:109990. S0306-9877(20)30544-2. doi: 10.1016/j.mehy.2020.109990.Epub 2020-06-13.

高インスリン血症は、アンジオポエチン-2の発現と放出の増加を介して内皮の炎症を促進する

Hyperinsulinemia promotes endothelial inflammation via increased expression and release of Angiopoietin-2.
  • Shivam Chandel
  • Anuradha Sathis
  • Monalisa Dhar
  • Hemant Giri
  • Abel Arul Nathan
  • Sai Kiran Reddy Samawar
  • Akshari Gupta
  • Jayashree Gopal
  • Ranjani Harish
  • Viswanathan Mohan
  • Madhulika Dixit
  • Atherosclerosis.2020 Jul;307:1-10. S0021-9150(20)30323-3. doi: 10.1016/j.atherosclerosis.2020.06.016.Epub 2020-07-05.

現代における濾胞性リンパ腫:生存率、治療成績、高リスクサブグループの同定

Follicular lymphoma in the modern era: survival, treatment outcomes, and identification of high-risk subgroups.
  • Connie L Batlevi
  • Fushen Sha
  • Anna Alperovich
  • Ai Ni
  • Katy Smith
  • Zhitao Ying
  • Jacob D Soumerai
  • Philip C Caron
  • Lorenzo Falchi
  • Audrey Hamilton
  • Paul A Hamlin
  • Steven M Horwitz
  • Erel Joffe
  • Anita Kumar
  • Matthew J Matasar
  • Alison J Moskowitz
  • Craig H Moskowitz
  • Ariela Noy
  • Colette Owens
  • Lia M Palomba
  • David Straus
  • Gottfried von Keudell
  • Andrew D Zelenetz
  • Venkatraman E Seshan
  • Anas Younes
  • Blood Cancer J.2020 Jul;10(7):74. 10.1038/s41408-020-00340-z. doi: 10.1038/s41408-020-00340-z.Epub 2020-07-17.

珍しい原発部位を含む副腎外傍神経節腫における68Ga-DOTANOCポジトロン断層撮影・コンピュータ断層撮影および131I-meta-ヨードベンジルグアニジン単光子放出型コンピュータ断層撮影・コンピュータ断層撮影の前向きな評価と現在のシナリオにおける診断上の役割を明らかにした

Prospective evaluation of 68Ga-DOTANOC positron emission tomography/computed tomography and 131I-meta-iodobenzylguanidine single-photon emission computed tomography/computed tomography in extra-adrenal paragangliomas, including uncommon primary sites and to define their diagnostic roles in current scenario.
  • Saurabh Arora
  • Rakesh Kumar
  • Averilicia Passah
  • Madhavi Tripathi
  • Sandeep Agarwala
  • Rajesh Khadgawat
  • Chandrasekhar Bal
  • Nucl Med Commun.2019 Dec;40(12):1230-1242. doi: 10.1097/MNM.0000000000001096.

構造に基づく仮想スクリーニング、分子動力学、密度汎関数理論研究を通じた新規コロナウイルス2019の潜在的阻害剤の計算科学的検討

Computational investigation of potential inhibitors of novel coronavirus 2019 through structure-based virtual screening, molecular dynamics and density functional theory studies.
  • Shashank Shekhar Mishra
  • Shashi Ranjan
  • Chandra Shekhar Sharma
  • Hemendra Pratap Singh
  • Sourav Kalra
  • Neeraj Kumar
  • J. Biomol. Struct. Dyn..2020 Jul;:1-13. doi: 10.1080/07391102.2020.1791957.Epub 2020-07-15.

ラットにおける四塩化炭素誘発性酸化ストレス及び遺伝子毒性に対するシリマリンナノ粒子の作製、特性評価及び生物学的評価

Fabrication, characterization and biological evaluation of silymarin nanoparticles against carbon tetrachloride-induced oxidative stress and genotoxicity in rats.
  • Mohamed H A Aboshanab
  • Mohamed A El-Nabarawi
  • Mahmoud H Teaima
  • Aziza A El-Nekeety
  • Sekena H Abdel-Aziem
  • Nabila S Hassan
  • Mosaad A Abdel-Wahhab
  • Int J Pharm.2020 Jul;:119639. S0378-5173(20)30623-2. doi: 10.1016/j.ijpharm.2020.119639.Epub 2020-07-13.

ガラパゴス海イグアナのプロテオミクスは、大腿腺タンパク質の機能と免疫システムを結びつけている

Proteomics of Galápagos marine iguanas links function of femoral gland proteins to the immune system.
  • Frederik Tellkamp
  • Franziska Lang
  • Alejandro Ibáñez Ricoma
  • Lena Abraham
  • Galo Quezada
  • Stefan Günther
  • Mario Looso
  • Fabian Jannik Tann
  • Daniela Müller
  • Franz Cemic
  • Jürgen Hemberger
  • Sebastian Steinfartz
  • Marcus Krüger
  • Mol. Cell Proteomics.2020 Jun;mcp.RA120.001947. doi: 10.1074/mcp.RA120.001947.Epub 2020-06-24.

頸椎横動脈を吻合した中鎖骨再石灰化性骨非ユニオンの治療に対する大腿骨内側コンダイル血管化骨移植術

Medial Femoral Condyle Vascularized Bone Graft for Treatment of Midshaft Clavicle Recalcitrant Nonunion With Use of the Transverse Cervical Artery as an Anastomosis.
  • Christopher M Belyea
  • Jefferson L Lansford
  • Joseph B Golden
  • Emily H Shin
  • Rey D L Gumboc
  • J Am Acad Orthop Surg Glob Res Rev.2020 Jun;4(6). e19.00049. doi: 10.5435/JAAOSGlobal-D-19-00049.Epub 2020-06-01.

小児がん生存者における散発性甲状腺がんと比較した小児がん生存者における後続の甲状腺がんの発現と転帰:全国一致調査

Presentation and outcome of subsequent thyroid cancer among childhood cancer survivors compared to sporadic thyroid cancer: a matched national study.
  • Sarah C Clement
  • Chantal A Lebbink
  • Mariëlle S Klein Hesselink
  • Jop C Teepen
  • Thera P Links
  • Cecile M Ronckers
  • Hanneke M van Santen
  • Eur. J. Endocrinol..2020 Aug;183(2):169-180. EJE-20-0153. doi: 10.1530/EJE-20-0153.

FUS変異体ヒト運動ニューロンのプロテオミクス解析から、3'UTR結合を介して細胞骨格や他のALS関連タンパク質の制御が変化していることが明らかになった

Proteomics analysis of FUS mutant human motoneurons reveals altered regulation of cytoskeleton and other ALS-linked proteins via 3'UTR binding.
  • Maria Giovanna Garone
  • Vincenzo Alfano
  • Beatrice Salvatori
  • Clarissa Braccia
  • Giovanna Peruzzi
  • Alessio Colantoni
  • Irene Bozzoni
  • Andrea Armirotti
  • Alessandro Rosa
  • Sci Rep.2020 Jul;10(1):11827. 10.1038/s41598-020-68794-6. doi: 10.1038/s41598-020-68794-6.Epub 2020-07-16.

筋萎縮性側索硬化症におけるアストロサイトを介したオートファジーの過剰活性化と運動ニューロン機能の低下のメカニズムを明らかにした

Mechanistic Insights of Astrocyte-Mediated Hyperactive Autophagy and Loss of Motor Neuron Function in SOD1 Linked Amyotrophic Lateral Sclerosis.
  • Chetan Singh Rajpurohit
  • Vivek Kumar
  • Arquimedes Cheffer
  • Danyllo Oliveira
  • Henning Ulrich
  • Oswaldo Keith Okamoto
  • Mayana Zatz
  • Uzair Ahmad Ansari
  • Vinay Kumar Khanna
  • Aditya Bhushan Pant
  • Mol. Neurobiol..2020 Jul;10.1007/s12035-020-02006-0. doi: 10.1007/s12035-020-02006-0.Epub 2020-07-16.

大規模培養コレクションからの海洋従属栄養細菌の多様性と分布

Diversity and distribution of marine heterotrophic bacteria from a large culture collection.
  • Isabel Sanz-Sáez
  • Guillem Salazar
  • Pablo Sánchez
  • Elena Lara
  • Marta Royo-Llonch
  • Elisabet L Sà
  • Teresa Lucena
  • María J Pujalte
  • Dolors Vaqué
  • Carlos M Duarte
  • Josep M Gasol
  • Carlos Pedrós-Alió
  • Olga Sánchez
  • Silvia G Acinas
  • BMC Microbiol..2020 Jul;20(1):207. 10.1186/s12866-020-01884-7. doi: 10.1186/s12866-020-01884-7.Epub 2020-07-13.

Fcγ受容体媒介ファゴサイトーシス経路の遺伝子における新規遺伝子変異が非小細胞肺癌の生存を予測することを明らかにした

Novel genetic variants in genes of the Fc gamma receptor-mediated phagocytosis pathway predict non-small cell lung cancer survival.
  • Danwen Qian
  • Hongliang Liu
  • Lingling Zhao
  • Xiaomeng Wang
  • Sheng Luo
  • Patricia G Moorman
  • Edward F Patz
  • Li Su
  • Sipeng Shen
  • David C Christiani
  • Qingyi Wei
  • Transl Lung Cancer Res.2020 Jun;9(3):575-586. tlcr-09-03-575. doi: 10.21037/tlcr-19-318.

脳腫瘍患者における分子腫瘍バイオマーカー検出における液体生検の役割

The Role of Liquid Biopsies in Detecting Molecular Tumor Biomarkers in Brain Cancer Patients.
  • Heena Sareen
  • Celine Garrett
  • David Lynch
  • Branka Powter
  • Daniel Brungs
  • Adam Cooper
  • Joseph Po
  • Eng-Siew Koh
  • Joey Yusof Vessey
  • Simon McKechnie
  • Renata Bazina
  • Mark Sheridan
  • James van Gelder
  • Balsam Darwish
  • Mathias Jaeger
  • Tara L Roberts
  • Paul De Souza
  • Therese M Becker
  • Cancers (Basel).2020 Jul;12(7). E1831. doi: 10.3390/cancers12071831.Epub 2020-07-08.

筋萎縮性側索硬化症モデルのhSOD1マウスにおける高度糖化最終生成物(RAGE)受容体の欠失は、炎症を抑制し、生存期間を延長する

Absence of Receptor for Advanced Glycation End Product (RAGE) Reduces Inflammation and Extends Survival in the hSOD1 Mouse Model of Amyotrophic Lateral Sclerosis.
  • John D Lee
  • Tanya S McDonald
  • Jenny N T Fung
  • Trent M Woodruff
  • Mol. Neurobiol..2020 Jul;10.1007/s12035-020-02019-9. doi: 10.1007/s12035-020-02019-9.Epub 2020-07-16.

プラスミドpCRT01の生体内での作製とその利用による産業廃棄物で効率的に生育するカロテノイド産生パラコッカス株の構築

In vivo creation of plasmid pCRT01 and its use for the construction of carotenoid-producing Paracoccus spp. strains that grow efficiently on industrial wastes.
  • Anna Maj
  • Lukasz Dziewit
  • Lukasz Drewniak
  • Maciej Garstka
  • Tomasz Krucon
  • Katarzyna Piatkowska
  • Katarzyna Gieczewska
  • Jakub Czarnecki
  • Ewa Furmanczyk
  • Robert Lasek
  • Jadwiga Baj
  • Dariusz Bartosik
  • Microb. Cell Fact..2020 Jul;19(1):141. 10.1186/s12934-020-01396-z. doi: 10.1186/s12934-020-01396-z.Epub 2020-07-13.

筋萎縮性側索硬化症における運動誘発電位:下部運動ニューロン表現型における不顕性UMNの関与を検出するための潜在的な意味合い

Motor-evoked potentials in amyotrophic lateral sclerosis: potential implications in detecting subclinical UMN involvement in lower motor neuron phenotype.
  • Stefano Zoccolella
  • Antonella Mastronardi
  • Antonio Scarafino
  • Giovanni Iliceto
  • Eustachio D'Errico
  • Angela Fraddosio
  • Irene Tempesta
  • Antonella Morea
  • Gaspare Scaglione
  • Alessandro Introna
  • Isabella Laura Simone
  • J. Neurol..2020 Jul;10.1007/s00415-020-10073-5. doi: 10.1007/s00415-020-10073-5.Epub 2020-07-16.

骨髄異形成症候群患者が安全に輸血を見送ることができる最低ヘモグロビン値のコンセンサス

Consensus minimum hemoglobin level above which patients with myelodysplastic syndromes can safely forgo transfusions.
  • Anna M Tanasijevic
  • Anna Revette
  • Heidi D Klepin
  • Amer Zeidan
  • Danielle Townsley
  • Courtney D DiNardo
  • Marie Sebert
  • Amy E DeZern
  • Richard M Stone
  • Emily S Magnavita
  • Richard Chen
  • Mikkael A Sekeres
  • Gregory A Abel
  • Leuk. Lymphoma.2020 Jul;:1-5. doi: 10.1080/10428194.2020.1791854.Epub 2020-07-15.

骨髄異形成症候群から二次性急性骨髄性白血病への進行に伴うコヘシン複合体とRasシグナル伝達変異の共起

Co-occurrence of cohesin complex and Ras signaling mutations during progression from myelodysplastic syndromes to secondary acute myeloid leukemia.
  • Marta Martín-Izquierdo
  • María Abáigar
  • Jesús M Hernández-Sánchez
  • David Tamborero
  • Félix López-Cadenas
  • Fernando Ramos
  • Eva Lumbreras
  • Andrés Madinaveitia-Ochoa
  • Marta Megido
  • Jorge Labrador
  • Javier Sánchez-Real
  • Carmen Olivier
  • Julio Dávila
  • Carlos Aguilar
  • Juan N Rodríguez
  • Guillermo Martín-Nuñez
  • Sandra Santos-Mínguez
  • Cristina Miguel-García
  • Rocío Benito
  • María Díez-Campelo
  • Jesús M Hernández-Rivas
  • Haematologica.2020 Jul;haematol.2020.248807. doi: 10.3324/haematol.2020.248807.Epub 2020-07-16.

エピジェネティックドラッグライブラリーのスクリーニングにより、4-((ヒドロキシアミノ)カルボニル)--(2-ヒドロキシエチル)--フェニルベンゼンアセトアミドがチロシナーゼ活性を阻害してメラニン合成を抑制することを明らかにした

Screening of an Epigenetic Drug Library Identifies 4-((hydroxyamino)carbonyl)--(2-hydroxyethyl)--Phenyl-Benzeneacetamide that Reduces Melanin Synthesis by Inhibiting Tyrosinase Activity Independently of Epigenetic Mechanisms.
  • Hyerim Song
  • Yun Jeong Hwang
  • Jae Won Ha
  • Yong Chool Boo
  • Int J Mol Sci.2020 Jun;21(13). E4589. doi: 10.3390/ijms21134589.Epub 2020-06-28.

新規のGa-mCXCL12 PETトレーサーを用いた急性心筋梗塞マウスモデルにおける心臓CXCR4発現の分子イメージング

Molecular imaging of cardiac CXCR4 expression in a mouse model of acute myocardial infarction using a novel Ga-mCXCL12 PET tracer.
  • Mathias Johannes Zacherl
  • Andrei Todica
  • Carmen Wängler
  • Ralf Schirrmacher
  • Mohammad Ali Hajebrahimi
  • Joachim Pircher
  • Xiang Li
  • Simon Lindner
  • Matthias Brendel
  • Peter Bartenstein
  • Steffen Massberg
  • Stefan Brunner
  • Sebastian Lehner
  • Marcus Hacker
  • Bruno C Huber
  • J Nucl Cardiol.2020 Jul;10.1007/s12350-020-02262-6. doi: 10.1007/s12350-020-02262-6.Epub 2020-07-16.

活動性難治性関節リウマチにおける生物学的製剤と二重濾過プラスマフェレーシスの有効性と安全性。レトロスペクティブコホート研究

Efficacy and safety of dual filtration plasmapheresis combined with biological agents in active refractory rheumatod arthritis: A retrospective cohort study.
  • Yida Xing
  • Shouquan Wang
  • Changyan Liu
  • Hongjiang Wang
  • Mingli Zhao
  • Bo Jin
  • Xiaodan Kong
  • Medicine (Baltimore).2020 Jul;99(28):e20966. 00005792-202007100-00050. doi: 10.1097/MD.0000000000020966.

血清中抗スタフィロコッカス抗体の測定により、人工股関節感染症に対する術前吸引の陽性予測値が増加する

Measurement of Serum Anti-staphylococcal Antibodies Increases Positive Predictive Value of Preoperative Aspiration for Hip Prosthetic Joint Infection.
  • Thomas Bauer
  • Simon Marmor
  • Idir Ghout
  • Elsa Salomon
  • Faten El Sayed
  • Beate Heym
  • Jacques Ropers
  • Martin Rottman
  • Jean-Louis Gaillard
  • Anne-Laure Roux
  • Clin. Orthop. Relat. Res..2020 Jun;doi: 10.1097/CORR.0000000000001392.Epub 2020-06-30.

市販シュノーケルマスクのエアロゾル化汚染物質およびSARS-CoV2に対する個人防護装置としての保護レベル、呼吸安全性および実用性の評価

Evaluation of Protection Level, Respiratory Safety, and Practical Aspects of Commercially Available Snorkel Masks as Personal Protection Devices Against Aerosolized Contaminants and SARS-CoV2.
  • Peter Germonpre
  • Dirk Van Rompaey
  • Costantino Balestra
  • Int J Environ Res Public Health.2020 Jun;17(12). E4347. doi: 10.3390/ijerph17124347.Epub 2020-06-19.

HER2陽性の転移性乳がん患者を対象としたネラチニブ+カペシタビンとラパチニブ+カペシタビンの比較。第III相NALA試験

Neratinib Plus Capecitabine Versus Lapatinib Plus Capecitabine in HER2-Positive Metastatic Breast Cancer Previously Treated With ≥ 2 HER2-Directed Regimens: Phase III NALA Trial.
  • Cristina Saura
  • Mafalda Oliveira
  • Yin-Hsun Feng
  • Ming-Shen Dai
  • Shang-Wen Chen
  • Sara A Hurvitz
  • Sung-Bae Kim
  • Beverly Moy
  • Suzette Delaloge
  • William Gradishar
  • Norikazu Masuda
  • Marketa Palacova
  • Maureen E Trudeau
  • Johanna Mattson
  • Yoon Sim Yap
  • Ming-Feng Hou
  • Michelino De Laurentiis
  • Yu-Min Yeh
  • Hong-Tai Chang
  • Thomas Yau
  • Hans Wildiers
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  • Daniele Fagnani
  • Yen-Shen Lu
  • John Crown
  • Johnson Lin
  • Masato Takahashi
  • Toshimi Takano
  • Miki Yamaguchi
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  • Bin Yao
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  • Richard Bryce
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磁性Mg-Fe/LDHインターカレート活性炭複合体による廃水からの硝酸塩・リン酸塩除去.磁性Mg-Fe/LDHインターカレート活性炭複合体の挙動とメカニズムの解明

Magnetic Mg-Fe/LDH Intercalated Activated Carbon Composites for Nitrate and Phosphate Removal from Wastewater: Insight into Behavior and Mechanisms.
  • Omar Alagha
  • Mohammad Saood Manzar
  • Mukarram Zubair
  • Ismail Anil
  • Nuhu Dalhat Mu'azu
  • Aleem Qureshi
  • Nanomaterials (Basel).2020 Jul;10(7). E1361. doi: 10.3390/nano10071361.Epub 2020-07-12.

食品接触材料に使用されるフタル酸ジ-ブチル(DBP)、フタル酸ブチルベンジル(BBP)、フタル酸ビス(2-エチルヘキシル)(DEHP)、フタル酸ジ-イソノニル(DINP)およびフタル酸ジ-イソデシル(DIDP)のリスク評価の更新

Update of the risk assessment of di-butylphthalate (DBP), butyl-benzyl-phthalate (BBP), bis(2-ethylhexyl)phthalate (DEHP), di-isononylphthalate (DINP) and di-isodecylphthalate (DIDP) for use in food contact materials.
  • Vittorio Silano
  • José Manuel Barat Baviera
  • Claudia Bolognesi
  • Andrew Chesson
  • Pier Sandro Cocconcelli
  • Riccardo Crebelli
  • David Michael Gott
  • Konrad Grob
  • Evgenia Lampi
  • Alicja Mortensen
  • Gilles Rivière
  • Inger-Lise Steffensen
  • Christina Tlustos
  • Henk Van Loveren
  • Laurence Vernis
  • Holger Zorn
  • Jean-Pierre Cravedi
  • Cristina Fortes
  • Maria de Fatima Tavares Poças
  • Ine Waalkens-Berendsen
  • Detlef Wölfle
  • Davide Arcella
  • Claudia Cascio
  • Anna F Castoldi
  • Katharina Volk
  • Laurence Castle
  • EFSA J.2019 Dec;17(12):e05838. EFS25838. doi: 10.2903/j.efsa.2019.5838.Epub 2019-12-11.

メラノコルチン-4受容体の活性化は、エタノールへの早期曝露とそれに続く成人期の自発的アルコール摂取によって誘発される神経炎症を抑制することを動物モデルで示した。BDNFが鍵となるメディエーターか?

Activation of Melanocortin-4 Receptor Inhibits Both Neuroinflammation Induced by Early Exposure to Ethanol and Subsequent Voluntary Alcohol Intake in Adulthood in Animal Models: Is BDNF the Key Mediator?
  • Osvaldo Flores-Bastías
  • Alfredo Adriasola-Carrasco
  • Eduardo Karahanian
  • Front Cell Neurosci.2020;14:5. doi: 10.3389/fncel.2020.00005.Epub 2020-01-28.

AJCC/TNM病期分類システムの第7版および第8版に従った甲状腺乳頭癌患者における放射性ヨード治療の生存率への影響:SEERに基づく研究

The impact of radioactive iodine treatment on survival among papillary thyroid cancer patients according to the 7th and 8th editions of the AJCC/TNM staging system: a SEER-based study.
  • Xiangxiang Liu
  • Yaguang Fan
  • Yuanchao Liu
  • Xianghui He
  • Xiangqian Zheng
  • Jian Tan
  • Qiang Jia
  • Zhaowei Meng
  • Updates Surg.2020 Apr;10.1007/s13304-020-00773-y. doi: 10.1007/s13304-020-00773-y.Epub 2020-04-27.

コルチコステロン誘発慢性ストレスモデルにおける小胞体ストレスの調節を介したボルリノスタットによる認知機能の改善

Cognitive improvement by vorinostat through modulation of endoplasmic reticulum stress in a corticosterone-induced chronic stress model in mice.
  • Athira K V
  • Rajaram Mohanrao Madhana
  • Akhilesh Kumar Bais
  • Vijay Bahadur Singh
  • Arpit Malik
  • Swapnil Sinha
  • Mangala Lahkar
  • Pramod Kumar
  • Dr Pavan Kumar Samudrala
  • ACS Chem Neurosci.2020 Jul;doi: 10.1021/acschemneuro.0c00315.Epub 2020-07-16.

新しい機能性アッセイを用いた移植レシピエントおよび健康なコントロールにおける抗HCMV細胞媒介免疫応答の評価

Assessing Anti-HCMV Cell Mediated Immune Responses in Transplant Recipients and Healthy Controls Using a Novel Functional Assay.
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  • Sarah E Jackson
  • Eleanor Y Lim
  • George X Sedikides
  • Emma L Davies
  • Claire Atkinson
  • Megan McIntosh
  • Ester B M Remmerswaal
  • Georgina Okecha
  • Frederike J Bemelman
  • Richard J Stanton
  • Matthew Reeves
  • Mark R Wills
  • Front Cell Infect Microbiol.2020;10:275. doi: 10.3389/fcimb.2020.00275.Epub 2020-06-26.

精神科看護師の間でCRSCEベースのデスケーショントレーニングプログラムの有効性を評価する:クラスター無作為化比較試験のための研究プロトコル

Evaluating the effectiveness of a CRSCE-based de-escalation training program among psychiatric nurses: a study protocol for a cluster randomized controlled trial.
  • Junrong Ye
  • Aixiang Xiao
  • Chen Wang
  • Zhichun Xia
  • Lin Yu
  • Sijue Li
  • Jiankui Lin
  • Yao Liao
  • Yu Xu
  • Yun Lei Zhang
  • BMC Health Serv Res.2020 Jul;20(1):642. 10.1186/s12913-020-05506-w. doi: 10.1186/s12913-020-05506-w.Epub 2020-07-10.

局所進行直腸癌におけるネオアジュバント放射線治療の線量エスカレーション:最新の治療アプローチとアウトカムのシステマティックレビューとメタアナリシス

Neoadjuvant Radiotherapy Dose Escalation in Locally Advanced Rectal Cancer: a Systematic Review and Meta-analysis of Modern Treatment Approaches and Outcomes.
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  • J Elks
  • D Vignarajah
  • J Lagopoulos
  • M Min
  • Clin Oncol (R Coll Radiol).2020 Jul;S0936-6555(20)30242-9. doi: 10.1016/j.clon.2020.06.008.Epub 2020-07-12.

リハビリテーションへの入所の適切性:デルファイ法の適用による一連の基準と規則の定義

Appropriateness of admission to rehabilitation: definition of a set of criteria and rules through the application of the Delphi method.
  • Andrea Merlo
  • Francesca Rodà
  • Davide Carnevali
  • Niccolò Principi
  • Ludovico Grimoldi
  • Francesco Auxilia
  • Francesco Lombardi
  • Maurizio Maini
  • Rodolfo Brianti
  • Silvana Castaldi
  • Eur J Phys Rehabil Med.2020 Jul;S1973-9087.20.06148-1. doi: 10.23736/S1973-9087.20.06148-1.Epub 2020-07-15.

Mini-Organo.腫瘍学的スクリーニングと薬剤開発のための高速ハイスループット3D培養有機型アッセイ

The Mini-Organo: A rapid high-throughput 3D coculture organotypic assay for oncology screening and drug development.
  • Jessica L Chitty
  • Joanna N Skhinas
  • Elysse C Filipe
  • Shan Wang
  • Carmen Rodriguez Cupello
  • Rhiannon D Grant
  • Michelle Yam
  • Michael Papanicolaou
  • Gretel Major
  • Anaiis Zaratzian
  • Andrew M Da Silva
  • Michael Tayao
  • Claire Vennin
  • Paul Timpson
  • Chris D Madsen
  • Thomas R Cox
  • Cancer Rep (Hoboken).2020 Feb;3(1):e1209. doi: 10.1002/cnr2.1209.Epub 2019-08-01.

FOLFIRINOX後の進行膵臓癌に対するセカンドライン治療としてのジェムシタビン、ドセタキセル、カペシタビン、シスプラチンの安全性と有効性

Safety and Efficacy of Gemcitabine, Docetaxel, Capecitabine, Cisplatin as Second-line Therapy for Advanced Pancreatic Cancer After FOLFIRINOX.
  • Jean-David Fumet
  • Julie Vincent
  • Leila Bengrine
  • Audrey Hennequin
  • Laura Granconato
  • Remi Palmier
  • FranÇois Ghiringhelli
  • Anticancer Res..2020 Jul;40(7):4011-4015. 40/7/4011. doi: 10.21873/anticanres.14395.

プロスタグランジンアナログで治療された緑内障患者のメイボミアン腺形態に対する3%ジカフォソールの保護効果:12ヶ月間の追跡調査

The protective effect of 3% diquafosol on meibomian gland morphology in glaucoma patients treated with prostaglandin analogs: a 12-month follow-up study.
  • Yue Guo
  • Jun Young Ha
  • He Long Piao
  • Mi Sun Sung
  • Sang Woo Park
  • BMC Ophthalmol.2020 Jul;20(1):277. 10.1186/s12886-020-01550-6. doi: 10.1186/s12886-020-01550-6.Epub 2020-07-10.

心原性ショック患者の臨床像、管理、リスク層別化:性別は重要か?

Clinical picture, management and risk stratification in patients with cardiogenic shock: does gender matter?
  • Elena Collado-Lledó
  • Isaac Llaó
  • Mercedes Rivas-Lasarte
  • Victor González-Fernández
  • Francisco J Noriega
  • Francisco José Hernández-Perez
  • Oriol Alegre
  • Alessandro Sionis
  • Rosa M Lidón
  • Ana Viana-Tejedor
  • Javier Segovia-Cubero
  • Albert Ariza-Solé
  • BMC Cardiovasc Disord.2020 Apr;20(1):189. 10.1186/s12872-020-01467-4. doi: 10.1186/s12872-020-01467-4.Epub 2020-04-21.

免疫能力のある患者および免疫不全患者の末梢血を含む臨床検体中のBartonella henselae DNAの3つの入れ子増幅法による検出

Detection of Bartonella henselae DNA in clinical samples including peripheral blood of immune competent and immune compromised patients by three nested amplifications.
  • Karina Hatamoto Kawasato
  • Léa Campos de Oliveira
  • Paulo Eduardo Neves Ferreira Velho
  • Lidia Yamamoto
  • Gilda Maria Barbaro Del Negro
  • Thelma Suely Okay
  • Rev. Inst. Med. Trop. Sao Paulo.2013 Jan-Feb;55(1):1-6. S0036-46652013000100001. doi: 10.1590/s0036-46652013000100001.

ヒト初代NK細胞のCD38欠失は、ダラツムマブ誘発性フラトリシドを除去し、そのエフェクター活性を高める

CD38 deletion of human primary NK cells eliminates daratumumab-induced fratricide and boosts their effector activity.
  • Meisam Naeimi Kararoudi
  • Yuya Nagai
  • Ezgi Elmas
  • Marcelo de Souza Fernandes Pereira
  • Syed Abbas Ali
  • Philip Hollingsworth Imus
  • Darren Wethington
  • Ivan Borrello
  • Dean Anthony Lee
  • Gabriel Ghiaur
  • Blood.2020 Jun;blood.2020006200. doi: 10.1182/blood.2020006200.Epub 2020-06-20.

SARS-CoV-2分子検出の国際的な外部品質評価とCOVID-19パンデミック時の臨床検査室準備に関する調査、2020年4月/5月

International external quality assessment for SARS-CoV-2 molecular detection and survey on clinical laboratory preparedness during the COVID-19 pandemic, April/May 2020.
  • Veerle Matheeussen
  • Victor M Corman
  • Oliver Donoso Mantke
  • Elaine McCulloch
  • Christine Lammens
  • Herman Goossens
  • Daniela Niemeyer
  • Paul S Wallace
  • Paul Klapper
  • Hubert Gm Niesters
  • Christian Drosten
  • Margareta Ieven
  • Euro Surveill..2020 07;25(27). doi: 10.2807/1560-7917.ES.2020.25.27.2001223.

生涯のライブウェイトとライブウェイトの変化、および前回のボディコンディションスコア記録を用いたニワのボディコンディションスコアの予測

Predicting Ewe Body Condition Score Using Lifetime Liveweight and Liveweight Change, and Previous Body Condition Score Record.
  • Jimmy Semakula
  • Rene Anne Corner-Thomas
  • Stephen Todd Morris
  • Hugh Thomas Blair
  • Paul Richard Kenyon
  • Animals (Basel).2020 Jul;10(7). E1182. doi: 10.3390/ani10071182.Epub 2020-07-13.

若い子牛のルーメンマイクロバイオータの反復接種は、ルーメン原核微生物叢を一貫して有意に変調させないが、下痢を減少させる

Repeated Inoculation of Young Calves With Rumen Microbiota Does Not Significantly Modulate the Rumen Prokaryotic Microbiota Consistently but Decreases Diarrhea.
  • Dengpan Bu
  • Xin Zhang
  • Lu Ma
  • Tansol Park
  • Lingling Wang
  • Mengzhi Wang
  • Jianchu Xu
  • Zhongtang Yu
  • Front Microbiol.2020;11:1403. doi: 10.3389/fmicb.2020.01403.Epub 2020-06-24.

食道および食道胃接合部の腺癌における有害病理学的分類は、解剖学的サブタイプによらず、生存率とネオアジュバント療法への反応に影響を与える

Adverse Biology in Adenocarcinoma of the Esophagus and Esophagogastric Junction Impacts Survival and Response to Neoadjuvant Therapy Independent of Anatomic Subtype.
  • Noel E Donlon
  • Jessie A Elliott
  • Claire L Donohoe
  • Conor F Murphy
  • Tim Nugent
  • Brendan Moran
  • Sinead King
  • Narayanasamy Ravi
  • John V Reynolds
  • Ann. Surg..2020 Jul;doi: 10.1097/SLA.0000000000004184.Epub 2020-07-09.

ノルエピネフリントランスポーター由来のホーミングペプチドは、神経芽腫細胞への薬物送達ナノ粒子の迅速なエンドサイトーシスを可能にする

Norepinephrine transporter-derived homing peptides enable rapid endocytosis of drug delivery nanovehicles into neuroblastoma cells.
  • Yazan Haddad
  • Marketa Charousova
  • Hana Zivotska
  • Zbynek Splichal
  • Miguel Angel Merlos Rodrigo
  • Hana Michalkova
  • Sona Krizkova
  • Barbora Tesarova
  • Lukas Richtera
  • Petr Vitek
  • Kamila Stokowa-Soltys
  • David Hynek
  • Vedran Milosavljevic
  • Simona Rex
  • Zbynek Heger
  • J Nanobiotechnology.2020 Jul;18(1):95. 10.1186/s12951-020-00654-x. doi: 10.1186/s12951-020-00654-x.Epub 2020-07-13.

ヒトにおけるSARS-CoV-2感染後の血清学的分析のための迅速ゲルカード凝集アッセイ

Rapid Gel Card Agglutination Assays for Serological Analysis Following SARS-CoV-2 Infection in Humans.
  • Diana Alves
  • Rodrigo Curvello
  • Edward Henderson
  • Vidhishri Kesarwani
  • Julia A Walker
  • Samuel C Leguizamon
  • Heather McLiesh
  • Vikram Singh Raghuwanshi
  • Hajar Samadian
  • Erica M Wood
  • Zoe K McQuilten
  • Maryza Graham
  • Megan Wieringa
  • Tony M Korman
  • Timothy F Scott
  • Mark M Banaszak Holl
  • Gil Garnier
  • Simon R Corrie
  • ACS Sens.2020 Jul;doi: 10.1021/acssensors.0c01050.Epub 2020-07-16.

ウルトラナノ結晶ダイヤモンド電極を用いた網膜刺激のin vivoでの実現可能性

In vivo feasibility of epiretinal stimulation using ultrananocrystalline diamond electrodes.
  • Mohit N Shivdasani
  • Mihailo Evans
  • Owen Burns
  • Jonathan Yeoh
  • Penelope J Allen
  • David Nayagam
  • Joel Villalobos
  • Carla J Abbott
  • Chi D Luu
  • Nicholas L Opie
  • Anu Sabu
  • Alexia L Saunders
  • Michelle McPhedran
  • Lisa Cardamone
  • Ceara McGowan
  • Vanessa Maxim
  • Richard A Williams
  • Kate Fox
  • Rosemary Cicione
  • David J Garrett
  • Arman Ahnood
  • Kumaravelu Ganesan
  • Hamish Meffin
  • Anthony N Burkitt
  • Steven Prawer
  • Chris E Williams
  • Robert K Shepherd
  • J Neural Eng.2020 Jul;doi: 10.1088/1741-2552/aba560.Epub 2020-07-13.

高解像度コーンビームCTを用いた歯内療法的に修復された根管支柱の有無にかかわらず、歯内療法的に修復された歯の骨折の評価

Assessment of fractures in endodontically treated teeth restored with and without root canal posts using high-resolution cone beam computed tomography.
  • David Aristizabal-Elejalde
  • Luis-Ernesto Arriola-Guillén
  • Aron Aliaga-Del Castillo
  • Gustavo-Armando Ruíz-Mora
  • Yalil-Augusto Rodríguez-Cárdenas
  • J Clin Exp Dent.2020 Jun;12(6):e547-e554. 56854. doi: 10.4317/jced.56854.Epub 2020-06-01.

種からの化合物の最初の報告オリブ由来のトリテルペノイド(Malvaceae)のトリテルペノイド

First report of compounds from an species: Triterpenoids from Oliv. (Malvaceae).
  • Jules H Peyeino
  • Hermine L Maza Djomkam
  • Sidonie Beatrice Kenmogne
  • Moses Kiprotich Langat
  • Sani Mohammed Isyaka
  • Willifred Dongmo Tekapi Tsopgni
  • Jean Duplex Wansi
  • Alain Francois Kamdem Waffo
  • Nobert Sewald
  • Juliette Catherine Vardamides
  • Nat. Prod. Res..2020 Jun;:1-3. doi: 10.1080/14786419.2020.1782408.Epub 2020-06-29.

新規チロシナーゼ阻害剤およびフリーラジカルスカベンジャーとしての1,2,3-トリアゾール結合型5-ベンジリデン(チオ)バルビツール酸塩の開発

1,2,3-Triazole-linked 5-benzylidene (thio)barbiturates as novel tyrosinase inhibitors and free-radical scavengers.
  • Sara Ranjbar
  • Parisa-Sadat Shahvaran
  • Najmeh Edraki
  • Mahsima Khoshneviszadeh
  • Mahdieh Darroudi
  • Yaghoub Sarrafi
  • Mahshid Hamzehloueian
  • Mehdi Khoshneviszadeh
  • Arch. Pharm. (Weinheim).2020 Jul;:e2000058. doi: 10.1002/ardp.202000058.Epub 2020-07-08.

メタノール/(水)エタノール中での酸触媒によるα-O-4アリールエーテル結合開裂:有機溶媒前処理中のリグニンモデル化合物の脱重合を理解する

Acid-catalysed α-O-4 aryl-ether bond cleavage in methanol/(aqueous) ethanol: understanding depolymerisation of a lignin model compound during organosolv pretreatment.
  • Edita Jasiukaitytė-Grojzdek
  • Matej Huš
  • Miha Grilc
  • Blaž Likozar
  • Sci Rep.2020 Jul;10(1):11037. 10.1038/s41598-020-67787-9. doi: 10.1038/s41598-020-67787-9.Epub 2020-07-06.

放射線治療後のグリオーママクロファージ集団の動的変化は、抵抗性を克服するための戦略としてCSF-1R阻害を明らかにした

Dynamic changes in glioma macrophage populations after radiotherapy reveal CSF-1R inhibition as a strategy to overcome resistance.
  • Leila Akkari
  • Robert L Bowman
  • Jeremy Tessier
  • Florian Klemm
  • Shanna M Handgraaf
  • Marnix de Groot
  • Daniela F Quail
  • Lucie Tillard
  • Jules Gadiot
  • Jason T Huse
  • Dieta Brandsma
  • Johan Westerga
  • Colin Watts
  • Johanna A Joyce
  • Sci Transl Med.2020 Jul;12(552). eaaw7843. doi: 10.1126/scitranslmed.aaw7843.

ムピロシン,フシジン酸および/またはレタパムリン抵抗性を有するメチシリン耐性黄色ブドウ球菌の有病率と分子解析

Prevalence and molecular characterization of methicillin-resistant Staphylococcus aureus with mupirocin, fusidic acid and/or retapamulin resistance.
  • Wenjing Chen
  • Chunyan He
  • Han Yang
  • Wen Shu
  • Zelin Cui
  • Rong Tang
  • Chuanling Zhang
  • Qingzhong Liu
  • BMC Microbiol..2020 Jun;20(1):183. 10.1186/s12866-020-01862-z. doi: 10.1186/s12866-020-01862-z.Epub 2020-06-29.

α-リノレン酸を豊富に含む亜麻仁油がラットの性ステロイドホルモン-微生物-炎症軸を介して多嚢胞性卵巣症候群に有益な効果を発揮する

Dietary α-Linolenic Acid-Rich Flaxseed Oil Exerts Beneficial Effects on Polycystic Ovary Syndrome Through Sex Steroid Hormones-Microbiota-Inflammation Axis in Rats.
  • Ting Wang
  • Liping Sha
  • Yiwei Li
  • Lili Zhu
  • Zhen Wang
  • Ke Li
  • Haixia Lu
  • Ting Bao
  • Li Guo
  • Xiaoxia Zhang
  • Hao Wang
  • Front Endocrinol (Lausanne).2020;11:284. doi: 10.3389/fendo.2020.00284.Epub 2020-05-27.

抗IL-5受容体モノクローナル抗体ベンラリズマブを用いた好酸球性慢性鼻副鼻腔炎および好酸球性中耳炎の治療に成功した。症例報告

Successful treatment of eosinophilic chronic rhinosinusitis and eosinophilic otitis media using the anti-IL-5 receptor monoclonal antibody benralizumab: A case report.
  • Hiroki Kagoshima
  • Ryusuke Hori
  • Tsuyoshi Kojima
  • Yusuke Okanoue
  • Atsushi Taguchi
  • Hirotaka Yamamoto
  • Koki Hasebe
  • Kazuhiko Shoji
  • Respir Med Case Rep.2020;30:101135. S2213-0071(20)30192-1. doi: 10.1016/j.rmcr.2020.101135.Epub 2020-06-17.

還元型グラフェン酸化物複合負極材で効果的に内包された亜鉛フェライトを合成し、高速度リチウムイオン貯蔵用負極材として開発した

Synthesis of a zinc ferrite effectively encapsulated by reduced graphene oxide composite anode material for high-rate lithium ion storage.
  • Qingke Tan
  • Chao Wang
  • Yangdi Cao
  • Xuehua Liu
  • Haijie Cao
  • Guanglei Wu
  • Binghui Xu
  • J Colloid Interface Sci.2020 Jul;579:723-732. S0021-9797(20)30882-1. doi: 10.1016/j.jcis.2020.07.004.Epub 2020-07-05.

COVID-19との闘いにおけるナチュラルキラー細胞のユニークな自然記憶細胞集団に焦点を当てる。サイトメガロウイルス曝露のユビキティを利用する

Focusing On A Unique Innate Memory Cell Population Of Natural Killer Cells In The Fight Against COVID-19: Harnessing The Ubiquity Of Cytomegalovirus Exposure.
  • Sarita Rani Jaiswal
  • Pankaj Malhotra
  • Dipendra K Mitra
  • Suparno Chakrabarti
  • Mediterr J Hematol Infect Dis.2020;12(1):e2020047. mjhid-12-1-e2020047. doi: 10.4084/MJHID.2020.047.Epub 2020-07-01.

マルチモダリティ画像ガイド精密放射線研究プラットフォーム。X線、生物発光、蛍光トモグラフィーと放射線治療を統合したもの

A Multi-modality Image-guided Precision Radiation Research Platform: Integrating X-ray, Bioluminescence and Fluorescence Tomography with Radiotherapy.
  • Junwei Shi
  • Keying Xu
  • Amir Keyvanloo
  • Thirupandiyur S Udayakumar
  • Fei Yang
  • Yidong Yang
  • Int. J. Radiat. Oncol. Biol. Phys..2020 Jun;S0360-3016(20)31310-9. doi: 10.1016/j.ijrobp.2020.06.023.Epub 2020-06-22.

IL10RA は NPM1-ALK 陽性の未分化大細胞リンパ腫におけるクリゾチニブ感受性を調節する

IL10RA Modulates Crizotinib Sensitivity in NPM1-ALK-positive Anaplastic Large Cell Lymphoma.
  • Nina Prokoph
  • Nicola Anna Probst
  • Liam Changwoo Lee
  • Jack Michael Monahan
  • Jamie David Matthews
  • Huan-Chang Liang
  • Klaas Bahnsen
  • Ivonne A Montes-Mojarro
  • Elif Karaca Atabay
  • Geeta Geeta Sharma
  • Vikas Malik
  • Hugo Larose
  • Sorcha Denise Forde
  • Stephen Paul Ducray
  • Cosimo Lobello
  • Qi Wang
  • Shi-Lu Luan
  • Sarka Pospisilova
  • Carlo B Gambacorti-Passerini
  • Amos Burke
  • Shahid Pervez
  • Andishe Attarbaschi
  • Andrea Janikova
  • Helene Pacquement
  • Judith Landman-Parker
  • Anne Lambilliotte
  • Gudrun Schleiermacher
  • Wolfram Klapper
  • Ralf Jauch
  • Wilhelm Woessmann
  • Gilles Vassal
  • Lukas Kenner
  • Olaf Merkel
  • Luca Mologni
  • Roberto Chiarle
  • Laurence Brugieres
  • Birgit Geoerger
  • Isaia Barbieri
  • Suzanne D Turner
  • Blood.2020 Jun;blood.2019003793. doi: 10.1182/blood.2019003793.Epub 2020-06-23.

脳神経外科用細胞外小胞からの小RNAのディープシークエンシングにより、miR-486-3pが神経膠芽腫と低悪性度の星細胞腫患者を区別する循環バイオマーカーとして実証された

Deep Sequencing of Small RNAs from Neurosurgical Extracellular Vesicles Substantiates miR-486-3p as a Circulating Biomarker that Distinguishes Glioblastoma from Lower-Grade Astrocytoma Patients.
  • Susannah Hallal
  • Saeideh Ebrahim Khani
  • Heng Wei
  • Maggie Yuk Ting Lee
  • Hao-Wen Sim
  • Joanne Sy
  • Brindha Shivalingam
  • Michael E Buckland
  • Kimberley L Alexander-Kaufman
  • Int J Mol Sci.2020 Jul;21(14). E4954. doi: 10.3390/ijms21144954.Epub 2020-07-13.

ブラジルにおける偶発的な胆振性カルキノーマに関する考察.

BRAZILIAN CONSENSUS ON INCIDENTAL GALLBLADDER CARCINOMA.
  • Felipe Jose F Coimbra
  • Orlando Jorge M Torres
  • Ruslan Alikhanov
  • Anil Agarwal
  • Patrick Pessaux
  • Eduardo de Souza M Fernandes
  • Claudemiro Quireze-Junior
  • Raphael Leonardo C Araujo
  • André Luis Godoy
  • Fabio Luis Waechter
  • Alexandre Prado de Resende
  • Marcio Fernando Boff
  • Gustavo Rego Coelho
  • Marcelo Bruno de Rezende
  • Marcelo Moura Linhares
  • Marcos Belotto
  • Jose Maria A Moraes-Junior
  • Paulo Cezar G Amaral
  • Rinaldo Danesi Pinto
  • Tercio Genzini
  • Agnaldo Soares Lima
  • Heber Salvador C Ribeiro
  • Eduardo José Ramos
  • Marciano Anghinoni
  • Lucio Lucas Pereira
  • Marcelo Enne
  • Adriano Sampaio
  • André Luis Montagnini
  • Alessandro Diniz
  • Victor Hugo Fonseca de Jesus
  • Bhawna Sirohi
  • Shailesh V Shrikhande
  • Renata D Alpino Peixoto
  • Antonio Nocchi Kalil
  • Nicolas Jarufe
  • Martin Smith
  • Paulo Herman
  • Arq Bras Cir Dig.2020 Jul;33(1):e1496. S0102-67202020000100306. doi: 10.1590/0102-672020190001e1496.

家族性ALSにおけるアデノ随伴ウイルスおよびマイクロRNAによる抑制

Suppression with Adeno-Associated Virus and MicroRNA in Familial ALS.
  • Christian Mueller
  • James D Berry
  • Diane M McKenna-Yasek
  • Gwladys Gernoux
  • Margaret A Owegi
  • Lindsay M Pothier
  • Catherine L Douthwright
  • Dario Gelevski
  • Sarah D Luppino
  • Meghan Blackwood
  • Nicholas S Wightman
  • Derek H Oakley
  • Matthew P Frosch
  • Terrence R Flotte
  • Merit E Cudkowicz
  • Robert H Brown
  • N. Engl. J. Med..2020 07;383(2):151-158. doi: 10.1056/NEJMoa2005056.

Millet and Debevec reへの反応:Patricianらによる「The Effect of an Expiratory Resistance Mask With Dead Space on Sleep, Acute Mountain Sickness, Cognition, and Ventilatory Acclimatization in Normobaric Hypoxia」と「Global REACH 2018.デッドスペース付き呼気抵抗性マスクの睡眠・急性高山病に対する影響と低気圧低酸素への急性曝露時の換気順応」(Carrら)

Response to Millet and Debevec re: "The Effect of an Expiratory Resistance Mask With Dead Space on Sleep, Acute Mountain Sickness, Cognition, and Ventilatory Acclimatization in Normobaric Hypoxia," by Patrician et al. and "Global REACH 2018: The Effect of an Expiratory Resistance Mask with Dead Space on Sleep and Acute Mountain Sickness During Acute Exposure to Hypobaric Hypoxia" by Carr et al.
  • Alexander Patrician
  • Jay Carr
  • Philip N Ainslie
  • High Alt. Med. Biol..2020 Jul;doi: 10.1089/ham.2020.0111.Epub 2020-07-13.

フィルター付き空気介入は、PM2.5曝露後の成人雄雌ラットにおいて、炎症と視床下部-下垂体-副腎軸の活性化を減少させることが示された

Filtered air intervention reduces inflammation and hypothalamus-pituitary-adrenal axis activation in adult male and female rats after PM 2.5 exposure.
  • Cuiying Liu
  • Jian Yang
  • Longfei Guan
  • Yuequan Zhu
  • Xiaokun Geng
  • Environ Sci Pollut Res Int.2020 Jun;10.1007/s11356-020-09564-9. doi: 10.1007/s11356-020-09564-9.Epub 2020-06-27.

TMPRSS2阻害剤候補のコンピュータ支援スクリーニング:ファーマコフォアモデリング、分子ドッキング、分子動力学シミュレーションの組み合わせ

Computer-aided screening for potential TMPRSS2 inhibitors: a combination of pharmacophore modeling, molecular docking and molecular dynamics simulation approaches.
  • Mukhtar Oluwaseun Idris
  • Abeeb Abiodun Yekeen
  • Oluwaseun Suleiman Alakanse
  • Olanrewaju Ayodeji Durojaye
  • J. Biomol. Struct. Dyn..2020 Jul;:1-19. doi: 10.1080/07391102.2020.1792346.Epub 2020-07-16.

III期非小細胞肺癌に対する化学放射線併用療法の有望な治療スケジュール.数理解析を用いた従来の分画に代わるもの.

The Promising Treatment Schedule of Concurrent Chemoradiotherapy for Stage III Non-small Cell Lung Cancer: Alternative for Conventional Fractionation Using Mathematical Analysis.
  • Yoshihiro Ueda
  • Osamu Suzuki
  • Shingo Ohira
  • Masashi Yagi
  • Iori Sumida
  • Kentaro Wada
  • Shoki Inui
  • Masaru Isono
  • Masayoshi Miyazaki
  • Kazuhiko Ogawa
  • Teruki Teshima
  • Anticancer Res..2020 Jul;40(7):4095-4104. 40/7/4095. doi: 10.21873/anticanres.14408.

カフェインの摂取と有酸素運動を組み合わせることで、訓練を受けた人の注意力や精神運動能力の向上につながるのでしょうか?

Can caffeine intake combined with aerobic exercise lead to improvement in attentional and psychomotor performance in trained individuals?
  • Sergio Machado
  • Alberto Souza Sá Filho
  • Carlos Campos
  • Carolina Cavalcante de Paula
  • Fabyana Bernardes
  • Eric Murillo-Rodriguez
  • Geraldo A Maranhão Neto
  • Eduardo Lattari
  • IBRO Rep.2020 Jun;8:76-81. S2451-8301(20)30003-0. doi: 10.1016/j.ibror.2020.01.002.Epub 2020-02-13.

エッセンシャルオイルを配合した歯磨き粉のインビトロでの抗菌・抗バイオフィルム活性

In vitro anticariogenic and antibiofilm activities of toothpastes formulated with essential oils.
  • Isabela de Oliveira Carvalho
  • Gislaine Aparecida Purgato
  • Mayra Soares Píccolo
  • Virgínia Ramos Pizziolo
  • Rafael Ribeiro Coelho
  • Gaspar Diaz-Muñoz
  • Marisa Alves Nogueira Diaz
  • Arch. Oral Biol..2020 Jul;117:104834. S0003-9969(20)30212-0. doi: 10.1016/j.archoralbio.2020.104834.Epub 2020-07-09.

液体クロマトグラフィーと高分解能タンデム質量分析法を結合させた液体クロマトグラフィーによるEscherichia coli、Pseudomonas putidaおよびPseudomonas taiwanensisからの脂質Aの同定と構造的特徴付け

Identification and structural characterization of lipid A from Escherichia coli, Pseudomonas putida and Pseudomonas taiwanensis by liquid chromatography coupled to high resolution-tandem mass spectrometry.
  • Matti Froning
  • Patrick O Helmer
  • Heiko Hayen
  • Rapid Commun. Mass Spectrom..2020 Jul;:e8897. doi: 10.1002/rcm.8897.Epub 2020-07-16.

バックスプライシングによるトランスクリプトアイソフォーム(円形化RNA)は生物学的に関連する経路に影響を与え、NMIBC患者の層別化のための追加情報を提供します

Back-Splicing Transcript Isoforms (Circular RNAs) Affect Biologically Relevant Pathways and Offer an Additional Layer of Information to Stratify NMIBC Patients.
  • Anshita Goel
  • Douglas G Ward
  • Naheema S Gordon
  • Ben Abbotts
  • Maurice P Zeegers
  • K K Cheng
  • Nicholas D James
  • Richard T Bryan
  • Roland Arnold
  • Front Oncol.2020;10:812. doi: 10.3389/fonc.2020.00812.Epub 2020-05-22.

グリーソンスコアリングスケールの深層を行く前立腺の組織学的グレーディングとクリブリフォームパターン検出のためのエンドツーエンドの自動システム

Going deeper through the Gleason scoring scale: An automatic end-to-end system for histology prostate grading and cribriform pattern detection.
  • Julio Silva-Rodríguez
  • Adrián Colomer
  • María A Sales
  • Rafael Molina
  • Valery Naranjo
  • Comput Methods Programs Biomed.2020 Jul;195:105637. S0169-2607(20)31470-X. doi: 10.1016/j.cmpb.2020.105637.Epub 2020-07-04.

乾癬性関節炎患者における仙腸炎の有病率とMRI上の急性および構造変化

Prevalence of sacroiliitis and acute and structural changes on MRI in patients with psoriatic arthritis.
  • Marcio Vale Braga
  • Samily Cordeiro de Oliveira
  • Antonio Helder Costa Vasconcelos
  • Jailson Rodrigues Lopes
  • Carlos Leite de Macedo Filho
  • Lysiane Maria Adeodato Ramos
  • Carlos Ewerton Maia Rodrigues
  • Sci Rep.2020 Jul;10(1):11580. 10.1038/s41598-020-68456-7. doi: 10.1038/s41598-020-68456-7.Epub 2020-07-14.

膀胱の尿路上皮がんに対する根治的膀胱摘出術を受けた患者における周術期のグルココルチコイドとがん転移および生存率との関連。単施設レトロスペクティブ研究

Association between perioperative glucocorticoids and cancer metastasis and survival in patients undergoing radical cystectomy for urothelial carcinoma of the bladder: A single-center retrospective study.
  • Shiyu Mao
  • Yuan Wu
  • Ruiliang Wang
  • Yadong Guo
  • Jing Yuan
  • Wentao Zhang
  • Junfeng Zhang
  • Yang Yan
  • Xudong Yao
  • Investig Clin Urol.2020 Jul;61(4):382-389. doi: 10.4111/icu.2020.61.4.382.Epub 2020-05-18.

クルクミン前処理ヒト脂肪由来幹細胞と血小板豊富な血漿を共同移植することで、糖尿病ラットの創傷治癒が改善されることを示した

Curcumin preconditioned human adipose derived stem cells co-transplanted with platelet rich plasma improve wound healing in diabetic rats.
  • Hafiz Ghufran
  • Azra Mehmood
  • Maryam Azam
  • Hira Butt
  • Amna Ramzan
  • Muhammad Amin Yousaf
  • Asim Ejaz
  • Moazzam N Tarar
  • Sheikh Riazuddin
  • Life Sci..2020 Jul;:118091. S0024-3205(20)30842-0. doi: 10.1016/j.lfs.2020.118091.Epub 2020-07-12.

COVID-19入院患者の死亡率予測における心臓バイオマーカーの再定義

Redefining cardiac biomarkers in predicting mortality of inpatients with COVID-19.
  • Juan-Juan Qin
  • Xu Cheng
  • Feng Zhou
  • Fang Lei
  • Gauri Akolkar
  • Jingjing Cai
  • Xiao-Jing Zhang
  • Alice Blet
  • Jing Xie
  • Peng Zhang
  • Ye-Mao Liu
  • Zizhen Huang
  • Ling-Ping Zhao
  • Lijin Lin
  • Meng Xia
  • Ming-Ming Chen
  • Xiaohui Song
  • Liangjie Bai
  • Ze Chen
  • Xingyuan Zhang
  • Da Xiang
  • Jing Chen
  • Qingbo Xu
  • Xin-Liang Ma
  • Rhian M Touyz
  • Chen Gao
  • Haitao Wang
  • Liming Liu
  • Weiming Mao
  • Pengcheng Luo
  • Youqin Yan
  • Ping Ye
  • Manhua Chen
  • Guohua Chen
  • Lihua Zhu
  • Zhi-Gang She
  • Xiaodong Huang
  • Yufeng Yuan
  • Bing-Hong Zhang
  • Yibin Wang
  • Peter P Liu
  • Hongliang Li
  • Hypertension.2020 Jul;doi: 10.1161/HYPERTENSIONAHA.120.15528.Epub 2020-07-14.

hUMSC移植は、AMPK/mTORシグナル伝達経路を介してtheca間質細胞のオートファジーを阻害することにより、POIラットの卵巣機能を回復させる

hUMSC transplantation restores ovarian function in POI rats by inhibiting autophagy of theca-interstitial cells via the AMPK/mTOR signaling pathway.
  • Xueyan Lu
  • Hongchu Bao
  • Linlu Cui
  • Wenqian Zhu
  • Lianshuang Zhang
  • Zheng Xu
  • Xuejing Man
  • Yongli Chu
  • Qiang Fu
  • Hongqin Zhang
  • Stem Cell Res Ther.2020 Jul;11(1):268. 10.1186/s13287-020-01784-7. doi: 10.1186/s13287-020-01784-7.Epub 2020-07-03.

睡眠時間および睡眠の質と一般的な身体的および精神的障害との独立および複合的な関連。多民族集団ベースの研究からの結果

Independent and combined associations of sleep duration and sleep quality with common physical and mental disorders: Results from a multi-ethnic population-based study.
  • Lee Seng Esmond Seow
  • Xiao Wei Tan
  • Siow Ann Chong
  • Janhavi Ajit Vaingankar
  • Edimansyah Abdin
  • Saleha Shafie
  • Boon Yiang Chua
  • Derrick Heng
  • Mythily Subramaniam
  • PLoS ONE.2020;15(7):e0235816. PONE-D-19-31356. doi: 10.1371/journal.pone.0235816.Epub 2020-07-16.

ブラジル公衆衛生協会(ABRASCO)における健康における大衆教育とそのテーマ別グループの視点

Perspectives of Popular Education in Health and its Thematic Group at the Brazilian Association of Public Health (ABRASCO).
  • Luanda de Oliveira Lima
  • Maria Rocineide Ferreira da Silva
  • Pedro José Santos Carneiro Cruz
  • Renata Pekelman
  • Vanderleia Laodete Pulga
  • Vera Lúcia de Azevedo Dantas
  • Cien Saude Colet.2020 Jul;25(7):2737. S1413-81232020000702737. doi: 10.1590/1413-81232020257.26122020.

落葉大臼歯臼歯の歯髄移植術の臨床成績とレントゲン撮影成績に及ぼすLASER治療の効果。システマティックレビューとメタアナリシス

Effect of LASER therapy Vs conventional techniques on clinical and radiographic outcomes of deciduous molar pulpotomy: A systematic review and meta-analysis.
  • Vennila Chandran
  • Venkitachalam Ramanarayanan
  • Medhini Menon
  • Balagopal Varma
  • Vinita Sanjeevan
  • J Clin Exp Dent.2020 Jun;12(6):e588-e596. 56436. doi: 10.4317/jced.56436.Epub 2020-06-01.

高精度侵襲FFR、低コスト侵襲iFR、または非侵襲CFR?患者固有の計算モデルに基づく冠動脈狭窄の最適評価.

High Precision Invasive FFR, Low-Cost Invasive iFR, Or Non-Invasive CFR?: Optimum Assessment of Coronary Artery Stenosis Based on the Patient-Specific Computational Models.
  • Farshad Tajeddini
  • Mohammad Reza Nikmaneshi
  • Bahar Firoozabadi
  • Hossein Ali Pakravan
  • Seyed Hossein Ahmadi Tafti
  • Hossein Afshin
  • Int J Numer Method Biomed Eng.2020 Jul;:e3382. doi: 10.1002/cnm.3382.Epub 2020-07-04.

カザフスタン西部アクトベ地域における2009年から2018年までの胃がん。発生率、傾向、5年生存率

Gastric Cancer in Aktobe Region of Western Kazakhstan from 2009 to 2018: Incidence Rates, Trends, and Five-Year Survival.
  • Saule K Balmagambetova
  • Yerbol Z Bekmukhambetov
  • Anar B Tulyaeva
  • Yerbolat M Iztleuov
  • Gaziza A Smagulova
  • Arip K Koyshybaev
  • Olzhas N Urazayev
  • Saganaj T Djussembekov
  • Valeriy V Begunov
  • Irakli Kokhreidze
  • Asian Pac. J. Cancer Prev..2020 Jun;21(6):1645-1652. 89113. doi: 10.31557/APJCP.2020.21.6.1645.Epub 2020-06-01.

経カテーテル大動脈弁置換術後のナトリウム利尿ペプチドレベルとその後の臨床成績との関連

Association of Natriuretic Peptide Levels After Transcatheter Aortic Valve Replacement With Subsequent Clinical Outcomes.
  • Jared M O'Leary
  • Marie-Annick Clavel
  • Shmuel Chen
  • Kashish Goel
  • Brian O'Neill
  • Sammy Elmariah
  • Aaron Crowley
  • Maria C Alu
  • Vinod H Thourani
  • Martin B Leon
  • Philippe Pibarot
  • Brian R Lindman
  • JAMA Cardiol.2020 Jul;2768443. doi: 10.1001/jamacardio.2020.2614.Epub 2020-07-15.

COVID-19患者における向精神薬の安全性:エビデンスレビューと実践的勧告

Safety of psychotropic medications in people with COVID-19: evidence review and practical recommendations.
  • Giovanni Ostuzzi
  • Davide Papola
  • Chiara Gastaldon
  • Georgios Schoretsanitis
  • Federico Bertolini
  • Francesco Amaddeo
  • Alessandro Cuomo
  • Robin Emsley
  • Andrea Fagiolini
  • Giuseppe Imperadore
  • Taishiro Kishimoto
  • Giulia Michencigh
  • Michela Nosé
  • Marianna Purgato
  • Dursun Serdar
  • Brendon Stubbs
  • David Taylor
  • Graham Thornicroft
  • Philip B Ward
  • Christoph Hiemke
  • Christoph U Correll
  • Corrado Barbui
  • BMC Med.2020 07;18(1):215. 10.1186/s12916-020-01685-9. doi: 10.1186/s12916-020-01685-9.Epub 2020-07-15.

非重症閉塞性肺疾患患者における仮面性心不全と動的ハイパーインフレ、自律神経機能障害および運動検査パラメータとの関連

The link between dynamic hyperinflation, autonomic dysfunction and exercise testing parameters with masked heart failure in patients with non-severe obstructive pulmonary disease.
  • Radostina Vl Cherneva
  • Stefan Veselinov Denchev
  • Zheina Vl Cherneva
  • J Basic Clin Physiol Pharmacol.2020 Jul;/j/jbcpp.ahead-of-print/jbcpp-2019-0311/jbcpp-2019-0311.xml. doi: 10.1515/jbcpp-2019-0311.Epub 2020-07-13.

食品添加物としてのベンジルアルコール(E1519)の再評価

Re-evaluation of benzyl alcohol (E 1519) as food additive.
  • Maged Younes
  • Gabriele Aquilina
  • Laurence Castle
  • Karl-Heinz Engel
  • Paul Fowler
  • Peter Fürst
  • Rainer Gürtler
  • Ursula Gundert-Remy
  • Trine Husøy
  • Wim Mennes
  • Peter Moldeus
  • Agneta Oskarsson
  • Romina Shah
  • Ine Waalkens-Berendsen
  • Detlef Wölfle
  • Polly Boon
  • Riccardo Crebelli
  • Alessandro Di Domenico
  • Metka Filipič
  • Alicja Mortensen
  • Henk Van Loveren
  • Ruud Woutersen
  • Petra Gergelova
  • Alessandra Giarola
  • Federica Lodi
  • Maria Jose Frutos Fernandez
  • EFSA J.2019 Oct;17(10):e05876. EFS25876. doi: 10.2903/j.efsa.2019.5876.Epub 2019-10-30.

2020年3月12日~13日のCEPI/BC会議に向けたコンセンサスまとめ報告書。COVID-19ワクチンによる疾患増強リスクの評価

Consensus summary report for CEPI/BC March 12-13, 2020 meeting: Assessment of risk of disease enhancement with COVID-19 vaccines.
  • Paul-Henri Lambert
  • Donna M Ambrosino
  • Svein R Andersen
  • Ralph S Baric
  • Steven B Black
  • Robert T Chen
  • Cornelia L Dekker
  • Arnaud M Didierlaurent
  • Barney S Graham
  • Samantha D Martin
  • Deborah C Molrine
  • Stanley Perlman
  • Philip A Picard-Fraser
  • Andrew J Pollard
  • Chuan Qin
  • Kanta Subbarao
  • Jakob P Cramer
  • Vaccine.2020 06;38(31):4783-4791. S0264-410X(20)30709-X. doi: 10.1016/j.vaccine.2020.05.064.Epub 2020-05-25.

授乳初期の栄養失調は、雄性ラットの弧状・傍室経路と視床下部におけるCARTとα-MSHの食欲不振分子の発現機構に影響を与えます

Malnourishment during early lactation disrupts the ontogenetic distribution of the CART and α-MSH anorexigenic molecules in the arcuate/paraventricular pathway and lateral hypothalamus in male rats.
  • Michael L M Rocha
  • Priscilla P Fernandes
  • Frank Tenório
  • Alex C Manhães
  • Penha C Barradas
  • Brain Res..2020 Sep;1743:146906. S0006-8993(20)30262-6. doi: 10.1016/j.brainres.2020.146906.Epub 2020-05-27.

寄生原虫由来の二機能性クリプトスポリジウムホミニスTS-DHFRのTSダイマー界面を標的とした解析X線を用いて、新規なTSアロステリック阻害剤を同定しました

Targeting the TS dimer interface in bifunctional Cryptosporidium hominis TS-DHFR from parasitic protozoa: Virtual screening identifies novel TS allosteric inhibitors.
  • Victor G Ruiz
  • Daniel J Czyzyk
  • Vidya P Kumar
  • William L Jorgensen
  • Karen S Anderson
  • Bioorg. Med. Chem. Lett..2020 Aug;30(16):127292. S0960-894X(20)30402-9. doi: 10.1016/j.bmcl.2020.127292.Epub 2020-05-30.

ニュージャージー州水胞性口内炎ウイルスのマトリックスタンパク質(M51R)における単一のアミノ酸置換は、培養ポルシンマクロファージにおける複製に障害を与え、ブタにおける有意な減衰をもたらした

A Single Amino Acid Substitution in the Matrix Protein (M51R) of Vesicular Stomatitis New Jersey Virus Impairs Replication in Cultured Porcine Macrophages and Results in Significant Attenuation in Pigs.
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腸管透過性とIgAは心血管系炎症と連動した免疫性血管炎を誘発する

Intestinal Permeability and IgA Provoke Immune Vasculitis Linked to Cardiovascular Inflammation.
  • Magali Noval Rivas
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  • Thacyana T Carvalho
  • Amanda Abolhesn
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ブラジルの三次病院の集中治療室におけるKPC産生菌の特性評価

Characterization of KPC-Producing in an Intensive Care Unit of a Brazilian Tertiary Hospital.
  • Roumayne L Ferreira
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  • Marcelo Silva Folhas Damas
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  • Fabiana R de Góes
  • Emeline Boni Campanini
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  • Maria-Cristina da Silva Pranchevicius
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軽度の子宮内膜炎を有する乳牛のセファピリンによる人工授精後の子宮内治療に関するフィールド試験

Field trial on the post-insemination intrauterine treatment of dairy cows with mild endometritis with cephapirin.
  • Roland Schlegl
  • Marc Drillich
  • Panagiotis Ballas
  • Ulrike Reinländer
  • Michael Iwersen
  • Walter Baumgartner
  • Monika Ehling-Schulz
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  • Theriogenology.2020 Jun;156:20-26. S0093-691X(20)30375-7. doi: 10.1016/j.theriogenology.2020.06.024.Epub 2020-06-29.

口腔内液中のブタの生殖呼吸器症候群ウイルス、ブタのサーコウイルス2およびE型肝炎ウイルスの分子検出と糞便および血清中の検出との比較

Molecular detection of porcine reproductive and respiratory syndrome virus, porcine circovirus 2 and hepatitis E virus in oral fluid compared to their detection in faeces and serum.
  • Jan Plut
  • Urska Jamnikar-Ciglenecki
  • Marina Stukelj
  • BMC Vet. Res..2020 May;16(1):164. 10.1186/s12917-020-02378-4. doi: 10.1186/s12917-020-02378-4.Epub 2020-05-27.

hsa_circ_0026827 miR-188-3pをスポンギングすることでBeclin1とRUNX1シグナル伝達経路を介してヒト歯髄幹細胞の骨芽細胞分化を促進する

hsa_circ_0026827 Promotes Osteoblast Differentiation of Human Dental Pulp Stem Cells Through the Beclin1 and RUNX1 Signaling Pathways by Sponging miR-188-3p.
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  • Jing Pan
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  • Zhao Yang
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  • Yueting Lin
  • Jiang Tao
  • Front Cell Dev Biol.2020;8:470. doi: 10.3389/fcell.2020.00470.Epub 2020-06-26.

シアノバクテリアフラボダイロンの導入による電子シンクの追加提供が、様々な光強度下での植物の成長を向上させる

Providing an Additional Electron Sink by the Introduction of Cyanobacterial Flavodiirons Enhances Growth of Under Various Light Intensities.
  • Suresh Tula
  • Fahimeh Shahinnia
  • Michael Melzer
  • Twan Rutten
  • Rodrigo Gómez
  • Anabella F Lodeyro
  • Nicolaus von Wirén
  • Néstor Carrillo
  • Mohammad R Hajirezaei
  • Front Plant Sci.2020;11:902. doi: 10.3389/fpls.2020.00902.Epub 2020-06-25.

SCAMP1-TV2をサイレンシングすると、PUM2との相互作用により、INSM1のmRNA分解が促進され、乳がん細胞の悪性生物学的行動が抑制された

Silencing SCAMP1-TV2 Inhibited the Malignant Biological Behaviors of Breast Cancer Cells by Interaction With PUM2 to Facilitate INSM1 mRNA Degradation.
  • Wei Tao
  • Jun Ma
  • Jian Zheng
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  • Yunhui Liu
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  • Front Oncol.2020;10:613. doi: 10.3389/fonc.2020.00613.Epub 2020-05-27.

Disabled homolog 2 は、腫瘍関連マクロファージの転移促進活性を制御している

The Disabled homolog 2 controls pro-metastatic activity of tumor-associated macrophages.
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  • Rosalinda Trovato
  • Francesca Hofer
  • Vincenzo Ingangi
  • Francesco DE Sanctis
  • Stefano Ugel
  • Stefania Cane
  • Anna Simonelli
  • Alessia Lamolinara
  • Manuela Iezzi
  • Matteo Fassan
  • Massimo Rugge
  • Federico Boschi
  • Giulia Borile
  • Thomas Eisenhaure
  • Siranush Sarkizova
  • David Lieb
  • Nir Hacohen
  • Luca Azzolin
  • Stefano Piccolo
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  • Cancer Discov.2020 Jul;CD-20-0036. doi: 10.1158/2159-8290.CD-20-0036.Epub 2020-07-10.

AJCC/UICC病期分類は開発途上国の頭頸部がんにもまだ適切か?

Is AJCC/UICC Staging Still Appropriate for Head and Neck Cancers in Developing Countries?
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  • Julie Wetter
  • Jeffrey Otiti
  • Joyce Aswani
  • Anna Konney
  • Evelyne Diom
  • Kenneth Baidoo
  • Paul Onakoya
  • Rajab Mugabo
  • Patrick Noah
  • Victor Mashamba
  • Innocent Kundiona
  • Chege Macharia
  • Mohammed Garba Mainasara
  • Melesse Gebeyehu
  • Mesele Bogale
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  • Getachew Beza Melesse
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  • OTO Open.2020 Jul-Sep;4(3):2473974X20938313. 10.1177_2473974X20938313. doi: 10.1177/2473974X20938313.Epub 2020-07-06.

SARS-CoV-2 (COVID-19)の構造と進化のダイナモーム。進化とヒトゲノムへの洞察

SARS-CoV-2 (COVID-19) structural and evolutionary dynamicome: Insights into functional evolution and human genomics.
  • Ruchir Gupta
  • Jacob Charron
  • Cynthia L Stenger
  • Jared Painter
  • Hunter Steward
  • Taylor W Cook
  • William Faber
  • Austin Frisch
  • Eric Lind
  • Jacob Bauss
  • Xiaopeng Li
  • Olivia Sirpilla
  • Xavier Soehnlen
  • Adam Underwood
  • David Hinds
  • Michele Morris
  • Neil Lamb
  • Joseph A Carcillo
  • Caleb P Bupp
  • Bruce D Uhal
  • Surender Rajasekaran
  • Jeremy W Prokop
  • J. Biol. Chem..2020 Jun;jbc.RA120.014873. doi: 10.1074/jbc.RA120.014873.Epub 2020-06-25.

景観の多様性と食生活の多様性の概念的なつながり.学際的研究のためのロードマップ

Conceptual Links between Landscape Diversity and Diet Diversity: A Roadmap for Transdisciplinary Research.
  • Sarah E Gergel
  • Bronwen Powell
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  • Bioscience.2020 Jul;70(6):563-575. biaa048. doi: 10.1093/biosci/biaa048.Epub 2020-06-24.

細胞追跡のためのZr標識T細胞の検出限界:臨床PET/CTおよびPET/MRIを用いたin vitroイメージングアプローチ

Detection limit of Zr-labeled T cells for cellular tracking: an in vitro imaging approach using clinical PET/CT and PET/MRI.
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  • Roido Manavaki
  • Bala Attili
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  • Nick Bird
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  • Neel Patel
  • Bristi Basu
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  • Franklin I Aigbirhio
  • Joanne L Jones
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  • EJNMMI Res.2020 Jul;10(1):82. 10.1186/s13550-020-00667-5. doi: 10.1186/s13550-020-00667-5.Epub 2020-07-14.

軽度のコビド-19 を有する成人の早期治療に対するヒドロキシクロロキン。無作為化比較試験

Hydroxychloroquine for Early Treatment of Adults with Mild Covid-19: A Randomized-Controlled Trial.
  • Oriol Mitjà
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  • Núria Riera-Martí
  • Carla A Pérez
  • Clara Suñer
  • Pep Laporte
  • Pol Admella
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  • Mireia Clua
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  • Jordi Casabona
  • Gabriel Cuatrecasas
  • Paz Cañadas
  • Aleix Elizalde-Torrent
  • Robert Fabregat
  • Magí Farré
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  • Gemma Flores-Mateo
  • Esteve Muntada
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  • Silvia Narejos
  • Aroa N Gil-Ortega
  • Nuria Prat
  • Jordi Puig
  • Carles Quiñones
  • Juliana Reyes-Ureña
  • Ferran Ramírez-Viaplana
  • Lidia Ruiz
  • Eva Riveira-Muñoz
  • Alba Sierra
  • César Velasco
  • Rosa Maria Vivanco-Hidalgo
  • Alexis Sentís
  • Camila G-Beiras
  • Bonaventura Clotet
  • Martí Vall-Mayans
  • Clin. Infect. Dis..2020 Jul;ciaa1009. doi: 10.1093/cid/ciaa1009.Epub 2020-07-16.

酵素処理されたトマト植物からのリグノセルロース系繊維。酵素処理されたトマト植物からのリグノセルロース系繊維:特性評価と板紙製造への応用

Lignocellulosic fibres from enzyme-treated tomato plants: Characterisation and application in paperboard manufacturing.
  • Clelia Covino
  • Angela Sorrentino
  • Prospero Di Pierro
  • Graziana Roscigno
  • Anna PiaVece
  • Paolo Masi
  • Int. J. Biol. Macromol..2020 Jun;S0141-8130(20)33519-4. doi: 10.1016/j.ijbiomac.2020.06.077.Epub 2020-06-11.

空間領域解析は、大腸がんの再発リスクを予測し、関連する腫瘍微小環境ネットワークを推定する

Spatial domain analysis predicts risk of colorectal cancer recurrence and infers associated tumor microenvironment networks.
  • Shikhar Uttam
  • Andrew M Stern
  • Christopher J Sevinsky
  • Samantha Furman
  • Filippo Pullara
  • Daniel Spagnolo
  • Luong Nguyen
  • Albert Gough
  • Fiona Ginty
  • D Lansing Taylor
  • S Chakra Chennubhotla
  • Nat Commun.2020 Jul;11(1):3515. 10.1038/s41467-020-17083-x. doi: 10.1038/s41467-020-17083-x.Epub 2020-07-14.

血糖代謝異常患者のメタボリックシンドロームに対するジンリダ顆粒の効果を評価する無作為化臨床試験の基礎とデザイン

Basis and Design of a Randomized Clinical Trial to Evaluate the Effect of Jinlida Granules on Metabolic Syndrome in Patients With Abnormal Glucose Metabolism.
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  • Shuolong Han
  • Liping Chang
  • Huailin Gao
  • Yiru Zhao
  • Shenghui Zhao
  • Xuedong An
  • Guangyao Song
  • Chunli Piao
  • Fengmei Lian
  • Tong Xiao-Lin
  • Zhenhua Jia
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認知トレーニングの効果を検証するためには、認知トレーニングの効果を検証することが重要であり、そのためには、認知トレーニングの効果を検証することが重要である。認知トレーニングのための6つの患者と軽度の脳損傷を持つ患者のための臨床医から提供された認知トレーニングに続く神経イメージングと神経心理学的アウトカム

Neuroimaging and Neuropsychological Outcomes Following Clinician-Delivered Cognitive Training for Six Patients With Mild Brain Injury: A Multiple Case Study.
  • Amy Lawson Moore
  • Dick M Carpenter
  • Randolph L James
  • Terissa Michele Miller
  • Jeffrey J Moore
  • Elizabeth A Disbrow
  • Christina R Ledbetter
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Discoidin Domain Receptor 1 (DDR1)シグナルの標的化とβ-integrinとのクロストークが、コラーゲンタイプ1の結合に伴う乳がん化学増感の鍵となることが明らかになった

Targeting Discoidin Domain Receptor 1 (DDR1) Signaling and Its Crosstalk with β-integrin Emerges as a Key Factor for Breast Cancer Chemosensitization upon Collagen Type 1 Binding.
  • Fabian Baltes
  • Julia Caspers
  • Svenja Henze
  • Martin Schlesinger
  • Gerd Bendas
  • Int J Mol Sci.2020 Jul;21(14). E4956. doi: 10.3390/ijms21144956.Epub 2020-07-13.

マヌカ蜂蜜をベースにしたゲルとプロポリスのエッセンシャルオイルの犬種に対する抗菌剤としての体外での有効性

In Vitro Efficacy of Essential Oils from and , Manuka Honey-based Gel, and Propolis as Antibacterial Agents Against Canine Strains.
  • Gabriele Meroni
  • Elena Cardin
  • Charlotte Rendina
  • Valentina Rafaela Herrera Millar
  • Joel Fernando Soares Filipe
  • Piera Anna Martino
  • Antibiotics (Basel).2020 Jun;9(6). E344. doi: 10.3390/antibiotics9060344.Epub 2020-06-19.

アルゼンチンでは、混血個体の詳細なゲノム解析により、これまで認識されていなかった遺伝的先祖の構成要素が明らかになった

Fine-scale genomic analyses of admixed individuals reveal unrecognized genetic ancestry components in Argentina.
  • Pierre Luisi
  • Angelina García
  • Juan Manuel Berros
  • Josefina M B Motti
  • Darío A Demarchi
  • Emma Alfaro
  • Eliana Aquilano
  • Carina Argüelles
  • Sergio Avena
  • Graciela Bailliet
  • Julieta Beltramo
  • Claudio M Bravi
  • Mariela Cuello
  • Cristina Dejean
  • José Edgardo Dipierri
  • Laura S Jurado Medina
  • José Luis Lanata
  • Marina Muzzio
  • María Laura Parolin
  • Maia Pauro
  • Paula B Paz Sepúlveda
  • Daniela Rodríguez Golpe
  • María Rita Santos
  • Marisol Schwab
  • Natalia Silvero
  • Jeremias Zubrzycki
  • Virginia Ramallo
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Fusarium verticillioides 感染に対する 2 種類のトウモロコシ交配種の抵抗性の基礎レベルに関する生理学的および生化学的な洞察

Physiological and biochemical insights into the basal level of resistance of two maize hybrids in response to Fusarium verticillioides infection.
  • Isaias S Cacique
  • Luiz F C C Pinto
  • Carlos E Aucique-Pérez
  • João A Wordell Filho
  • Fabrício A Rodrigues
  • Plant Physiol. Biochem..2020 May;152:194-210. S0981-9428(20)30205-9. doi: 10.1016/j.plaphy.2020.04.036.Epub 2020-05-11.

小児散発性悪性末梢神経鞘腫瘍におけるリアルタイム治療指導のための患者由来の同所性異種移植モデルの使用

Use of patient derived orthotopic xenograft models for real-time therapy guidance in a pediatric sporadic malignant peripheral nerve sheath tumor.
  • Juana Fernández-Rodríguez
  • Andrés Morales La Madrid
  • Bernat Gel
  • Alicia Castañeda Heredia
  • Héctor Salvador
  • María Martínez-Iniesta
  • Catia Moutinho
  • Jordi Morata
  • Holger Heyn
  • Ignacio Blanco
  • Edgar Creus-Bachiller
  • Gabriel Capella
  • Lourdes Farré
  • August Vidal
  • Francisco Soldado
  • Lucas Krauel
  • Mariona Suñol
  • Eduard Serra
  • Alberto Villanueva
  • Conxi Lázaro
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Clinical Cancer Advances 2020.米国臨床腫瘍学会からのがんに対する進歩に関する年次報告書

Clinical Cancer Advances 2020: Annual Report on Progress Against Cancer From the American Society of Clinical Oncology.
  • Merry Jennifer Markham
  • Kerri Wachter
  • Neeraj Agarwal
  • Monica M Bertagnolli
  • Susan Marina Chang
  • William Dale
  • Catherine S M Diefenbach
  • Carlos Rodriguez-Galindo
  • Daniel J George
  • Timothy D Gilligan
  • R Donald Harvey
  • Melissa L Johnson
  • Randall J Kimple
  • Miriam A Knoll
  • Noelle LoConte
  • Robert G Maki
  • Jane Lowe Meisel
  • Jeffrey A Meyerhardt
  • Nathan A Pennell
  • Gabrielle B Rocque
  • Michael S Sabel
  • Richard L Schilsky
  • Bryan James Schneider
  • William D Tap
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北米におけるミトコンドリア疾患。NAMDC レジストリの分析

Mitochondrial diseases in North America: An analysis of the NAMDC Registry.
  • Emanuele Barca
  • Yuelin Long
  • Victoria Cooley
  • Robert Schoenaker
  • Valentina Emmanuele
  • Salvatore DiMauro
  • Bruce H Cohen
  • Amel Karaa
  • Georgirene D Vladutiu
  • Richard Haas
  • Johan L K Van Hove
  • Fernando Scaglia
  • Sumit Parikh
  • Jirair K Bedoyan
  • Susanne D DeBrosse
  • Ralitza H Gavrilova
  • Russell P Saneto
  • Gregory M Enns
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  • Jaya Ganesh
  • Austin Larson
  • Zarazuela Zolkipli-Cunningham
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  • Amy C Goldstein
  • Mark Tarnopolsky
  • Andrea Gropman
  • Kathryn Camp
  • Danuta Krotoski
  • Kristin Engelstad
  • Xiomara Q Rosales
  • Joshua Kriger
  • Johnston Grier
  • Richard Buchsbaum
  • John L P Thompson
  • Michio Hirano
  • Neurol Genet.2020 Apr;6(2):e402. NG2019011163. doi: 10.1212/NXG.0000000000000402.Epub 2020-03-02.

人体安全性評価のための新しいアプローチ手法(NAM)の評価フレームワーク

An evaluation framework for new approach methodologies (NAMs) for human health safety assessment.
  • Stanley T Parish
  • Michael Aschner
  • Warren Casey
  • Marco Corvaro
  • Michelle R Embry
  • Suzanne Fitzpatrick
  • Darren Kidd
  • Nicole C Kleinstreuer
  • Beatriz Silva Lima
  • Raja S Settivari
  • Douglas C Wolf
  • Daiju Yamazaki
  • Alan Boobis
  • Regul. Toxicol. Pharmacol..2020 Apr;112:104592. S0273-2300(20)30018-0. doi: 10.1016/j.yrtph.2020.104592.Epub 2020-02-01.

ミツバチコロニーにおける寄生虫の多様性に関する縦断的解析:新分類、混合感染の高頻度、季節的変動パターン

Longitudinal analysis on parasite diversity in honeybee colonies: new taxa, high frequency of mixed infections and seasonal patterns of variation.
  • Carolina Bartolomé
  • María Buendía-Abad
  • María Benito
  • Beatriz Sobrino
  • Jorge Amigo
  • Angel Carracedo
  • Raquel Martín-Hernández
  • Mariano Higes
  • Xulio Maside
  • Sci Rep.2020 Jun;10(1):10454. 10.1038/s41598-020-67183-3. doi: 10.1038/s41598-020-67183-3.Epub 2020-06-26.

毎日の起伏のあるピリオダイゼーションは、非ピリオド化トレーニングよりもHIV患者の最大筋力、有酸素運動能力、およびTCD4+細胞数に効果的である

Daily Undulating Periodization Is More Effective Than Nonperiodized Training on Maximal Strength, Aerobic Capacity, and TCD4+ Cell Count in People Living With HIV.
  • Vitor Lopes Soares
  • Weverton Fonseca Soares
  • Hugo Ribeiro Zanetti
  • Fernando Freitas Neves
  • Mário Leon Silva-Vergara
  • Edmar Lacerda Mendes
  • J Strength Cond Res.2020 Jun;doi: 10.1519/JSC.0000000000003675.Epub 2020-06-24.

母体分離は長期的な酸化ストレスの変化を誘導し、雄性Baldb/cJマウスの不安様行動を増加させる

Maternal separation induces long-term oxidative stress alterations and increases anxiety-like behavior of male Balb/cJ mice.
  • Luiza Martins Costa Malcon
  • Luis Eduardo Wearick-Silva
  • Aline Zaparte
  • Rodrigo Orso
  • Carolina Luft
  • Saulo Gantes Tractenberg
  • Márcio Vinicius Fagundes Donadio
  • Jarbas Rodrigues de Oliveira
  • Rodrigo Grassi-Oliveira
  • Exp Brain Res.2020 Jul;10.1007/s00221-020-05859-y. doi: 10.1007/s00221-020-05859-y.Epub 2020-07-12.

アジアクローン病・大腸炎機構およびアジア太平洋消化器病学会のアジアにおける炎症性腸疾患の医学的管理とモニタリングのための実践勧告

Asian Organization for Crohn's and Colitis and Asia Pacific Association of Gastroenterology Practice Recommendations for Medical Management and Monitoring of Inflammatory Bowel Disease in Asia.
  • Zhihua Ran
  • Kaichun Wu
  • Katsuyoshi Matsuoka
  • Yoon Tae Jeen
  • Shu Chen Wei
  • Vineet Ahuja
  • Minhu Chen
  • Pin-Jin Hu
  • Akira Andoh
  • Hyo Jong Kim
  • Suk-Kyun Yang
  • Mamoru Watanabe
  • Siew Chien Ng
  • Toshifumi Hibi
  • Ida Normiha Hilmi
  • Yasuo Suzuki
  • Dong Soo Han
  • Wai Keung Leung
  • Jose Sollano
  • Choon Jin Ooi
  • Jiaming Qian
  • J. Gastroenterol. Hepatol..2020 Jul;doi: 10.1111/jgh.15185.Epub 2020-07-16.

セレブロン欠失は、ARPE-19細胞における5'-アデノシン一リン酸活性化プロテインキナーゼ/ヘムオキシゲナーゼ-1活性化を介してリポ多糖類誘導性炎症性サイトカインを改善する

Cereblon Deletion Ameliorates Lipopolysaccharide-induced Proinflammatory Cytokines through 5'-Adenosine Monophosphate-Activated Protein Kinase/Heme Oxygenase-1 Activation in ARPE-19 Cells.
  • Yun Kyu Kim
  • Soo Chul Chae
  • Hun Ji Yang
  • Da Eun An
  • Sion Lee
  • Myeong Gu Yeo
  • Kyung Jin Lee
  • Immune Netw.2020 Jun;20(3):e26. 2020200307. doi: 10.4110/in.2020.20.e26.Epub 2020-06-25.

ウラン鉱滓からのウラン放出に及ぼす粒子径効果に関する重要な知見と示唆を得た。地球化学的及び鉱物学的側面からの考察

Critical insight and indication on particle size effects towards uranium release from uranium mill tailings: Geochemical and mineralogical aspects.
  • Meiling Yin
  • Daniel C W Tsang
  • Jing Sun
  • Jin Wang
  • Jianying Shang
  • Fa Fang
  • Yang Wu
  • Juan Liu
  • Gang Song
  • Tangfu Xiao
  • Diyun Chen
  • Chemosphere.2020 Jul;250:126315. S0045-6535(20)30508-7. doi: 10.1016/j.chemosphere.2020.126315.Epub 2020-02-26.

重症COVID-19患者の後期病理組織学的特徴。侵襲性アスペルギルス症の証拠を伴わない異なる表現型、1 症例シリーズ

Late histopathologic characteristics of critically ill COVID-19 patients: Different phenotypes without evidence of invasive aspergillosis, a case series.
  • Antine W Flikweert
  • Marco J J H Grootenboers
  • David C Y Yick
  • Arthur W F du Mée
  • Nardo J M van der Meer
  • Thijs C D Rettig
  • Merijn K M Kant
  • J Crit Care.2020 Jul;59:149-155. S0883-9441(20)30603-1. doi: 10.1016/j.jcrc.2020.07.002.Epub 2020-07-08.

超臨界状態の CO が薬物-ポリマー系の特性、溶解性、ビカルタミド含有錠の特性にどのような影響を与えるか?

How Does the CO in Supercritical State Affect the Properties of Drug-Polymer Systems, Dissolution Performance and Characteristics of Tablets Containing Bicalutamide?
  • Agata Antosik-Rogóż
  • Joanna Szafraniec-Szczęsny
  • Krzysztof Chmiel
  • Justyna Knapik-Kowalczuk
  • Mateusz Kurek
  • Karolina Gawlak
  • Vittorio P Danesi
  • Marian Paluch
  • Renata Jachowicz
  • Materials (Basel).2020 Jun;13(12). E2848. doi: 10.3390/ma13122848.Epub 2020-06-25.

安定した腎移植患者では,タクロリムスのトラフ値が6 ng/mLを超えても,1年後には必要とされない可能性がある

Tacrolimus trough levels higher than 6 ng/mL might not be required after a year in stable kidney transplant recipients.
  • Hee-Yeon Jung
  • Min Young Seo
  • Yena Jeon
  • Kyu Ha Huh
  • Jae Berm Park
  • Cheol Woong Jung
  • Sik Lee
  • Seung-Yeup Han
  • Han Ro
  • Jaeseok Yang
  • Curie Ahn
  • Ji-Young Choi
  • Jang-Hee Cho
  • Sun-Hee Park
  • Yong-Lim Kim
  • Chan-Duck Kim
  • PLoS ONE.2020;15(7):e0235418. PONE-D-20-13868. doi: 10.1371/journal.pone.0235418.Epub 2020-07-02.

軽度から中等度の開放角緑内障患者における白内障手術時の2つのTrabecular Microbypass Stentのカナダでの費用対効果の分析

A Canadian Cost-Utility Analysis of 2 Trabecular Microbypass Stents at Time of Cataract Surgery in Patients with Mild to Moderate Open-Angle Glaucoma.
  • Iqbal Ike K Ahmed
  • Dominik W Podbielski
  • Vardhaman Patel
  • Heather Falvey
  • Judith Murray
  • Marc Botteman
  • Ron Goeree
  • Ophthalmol Glaucoma.2020 Mar - Apr;3(2):103-113. S2589-4196(19)30350-3. doi: 10.1016/j.ogla.2019.11.009.Epub 2019-11-30.

重症コロナウイルス疾患2019(COVID-19)の治療における神煌顆粒の有効性と安全性:非盲検無作為化比較臨床試験の試験計画書

Shenhuang granule in the treatment of severe coronavirus disease 2019 (COVID-19): study protocol for an open-label randomized controlled clinical trial.
  • Bangjiang Fang
  • Wen Zhang
  • Xinxin Wu
  • Tingrong Huang
  • Huacheng Li
  • You Zheng
  • Jinhua Che
  • Shuting Sun
  • Chao Jiang
  • Shuang Zhou
  • Jun Feng
  • Trials.2020 Jun;21(1):568. 10.1186/s13063-020-04498-6. doi: 10.1186/s13063-020-04498-6.Epub 2020-06-24.

エストロゲン欠乏とストレプトゾトシン誘発糖尿病が雌ラットの歯周組織に及ぼす影響

Effects of estrogen deficiency followed by streptozotocin-induced diabetes on periodontal tissues of female rats.
  • Gisela Rodrigues da Silva Sasso
  • Rinaldo Florencio-Silva
  • Caio Cesar Navarrete da Fonseca
  • Luana Carvalho Cezar
  • Adriana Aparecida Ferraz Carbonel
  • Cristiane Damas Gil
  • Manuel de Jesus Simões
  • Manoel João Batista Castello Girão
  • J. Mol. Histol..2020 Jun;10.1007/s10735-020-09885-6. doi: 10.1007/s10735-020-09885-6.Epub 2020-06-03.

2005年から2019年までのポーランド小児白血病・リンパ腫研究グループにおけるダウン症の骨髄性白血病における治療成績のレトロスペクティブ分析

Retrospective Analysis of the Treatment Outcome in Myeloid Leukemia of Down Syndrome in Polish Pediatric Leukemia and Lymphoma Study Group From 2005 to 2019.
  • Malgorzata Czogala
  • Katarzyna Pawinska-Wasikowska
  • Teofila Ksiazek
  • Barbara Sikorska-Fic
  • Michal Matysiak
  • Jolanta Skalska-Sadowska
  • Jacek Wachowiak
  • Anna Rodziewicz-Konarska
  • Alicja Chybicka
  • Katarzyna Myszynska-Roslan
  • Maryna Krawczuk-Rybak
  • Dominik Grabowski
  • Jerzy Kowalczyk
  • Lucyna Maciejka-Kemblowska
  • Elzbieta Adamkiewicz-Drozynska
  • Katarzyna Bobeff
  • Wojciech Mlynarski
  • Renata Tomaszewska
  • Tomasz Szczepanski
  • Joanna Pohorecka
  • Agnieszka Chodala-Grzywacz
  • Grazyna Karolczyk
  • Agnieszka Mizia-Malarz
  • Katarzyna Mycko
  • Wanda Badowska
  • Karolina Zielezinska
  • Tomasz Urasinski
  • Magdalena Nykiel
  • Mariola Woszczyk
  • Malgorzata Ciebiera
  • Radosław Chaber
  • Szymon Skoczen
  • Walentyna Balwierz
  • Front Pediatr.2020;8:277. doi: 10.3389/fped.2020.00277.Epub 2020-06-19.

RIFM香料成分安全性評価、2-メチル酪酸ヘキシル、CAS登録番号10032-15-2

RIFM fragrance ingredient safety assessment, hexyl 2-methylbutyrate, CAS Registry Number 10032-15-2.
  • A M Api
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  • M A Cancellieri
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  • M Date
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  • M Na
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  • A Patel
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  • T W Schultz
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  • Y Thakkar
  • Y Tokura
  • S Tsang
  • Food Chem. Toxicol..2020 Jul;:111463. S0278-6915(20)30353-7. doi: 10.1016/j.fct.2020.111463.Epub 2020-07-05.

TEM プロービング、AFM ナノメカニカルマッピング、理論計算により明らかになった TiC MXene ナノシートのヤング率と引張強さ

Young's Modulus and Tensile Strength of TiC MXene Nanosheets As Revealed by TEM Probing, AFM Nanomechanical Mapping, and Theoretical Calculations.
  • Konstantin L Firestein
  • Joel E von Treifeldt
  • Dmitry G Kvashnin
  • Joseph F S Fernando
  • Chao Zhang
  • Alexander G Kvashnin
  • Evgeny V Podryabinkin
  • Alexander V Shapeev
  • Dumindu P Siriwardena
  • Pavel B Sorokin
  • Dmitri Golberg
  • Nano Lett..2020 Jul;doi: 10.1021/acs.nanolett.0c01861.Epub 2020-07-13.