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日本語AIでPubMedを検索

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日本語AIでPubMedを検索

PubMedの提供する医学論文データベースを日本語で検索できます。AI(Deep Learning)を活用した機械翻訳エンジンにより、精度高く日本語へ翻訳された論文をご参照いただけます。
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2020年07月 みんなが読んでいる論文

環境的に現実的な濃度の赤色分散染料（DR 60、DR 73およびDR 78）がゼブラフィッシュ（Danio rerio）の初期のライフステージの生化学的プロファイルに影響を与えた

Red disperse dyes (DR 60, DR 73 and DR 78) at environmentally realistic concentrations impact biochemical profile of early life stages of zebrafish (Danio rerio).
  • Gabriela Meireles
  • Michiel A Daam
  • Ana Letícia Madeira Sanches
  • Maria V B Zanoni
  • Amadeu M V M Soares
  • Carlos Gravato
  • Danielle P de Oliveira
  • Chem. Biol. Interact..2018 Aug;292:94-100. S0009-2797(18)30307-7. doi: 10.1016/j.cbi.2018.07.007.Epub 2018-07-10.

オンコセルカ症に関連したてんかんと結節性発作を持つ人は、認知機能障害とオンコセルカ・ボルビュラス感染症のレベルが高い、より重度のてんかんを持っています

Persons with onchocerciasis-associated epilepsy and nodding seizures have a more severe form of epilepsy with more cognitive impairment and higher levels of Onchocerca volvulus infection.
  • Gasim Abd-Elfarag
  • Jane Y Carter
  • Stephen Raimon
  • Wilson Sebit
  • Abozer Suliman
  • Joseph Nelson Siewe Fodjo
  • Peter Claver Olore
  • Kai Puok Biel
  • Morrish Ojok
  • Makoy Yibi Logora
  • Robert Colebunders
  • Epileptic Disord.2020 Jun;22(3):301-308. epd.2020.1164. doi: 10.1684/epd.2020.1164.

監督者のサービス効果を向上させるための患者報告アウトカム尺度の使用：児童精神保健におけるアウトカム尺度を使用するための研修後の監督者の態度と自己効力感の混合法評価

Using patient-reported outcome measures to improve service effectiveness for supervisors: a mixed-methods evaluation of supervisors' attitudes and self-efficacy after training to use outcome measures in child mental health.
  • Mary Fullerton
  • Julian Edbrooke-Childs
  • Duncan Law
  • Kate Martin
  • Isabelle Whelan
  • Miranda Wolpert
  • Child Adolesc Ment Health.2018 Feb;23(1):34-40. doi: 10.1111/camh.12206.Epub 2017-01-24.

アトピー性新生児におけるバリア機能障害の研究」（BABY）：デンマークの前向き出生コホート研究のプロトコール

'Barrier dysfunction in Atopic newBorns studY' (BABY): protocol of a Danish prospective birth cohort study.
  • Trine Gerner
  • Anne-Sofie Halling
  • Maria Rasmussen Rinnov
  • Nina Haarup Ravn
  • Mette Hjorslev Knudgaard
  • Charlotte Menné Bonefeld
  • Caroline Ewertsen
  • Simon Trautner
  • Ivone Jakaša
  • Sanja Kezic
  • Lone Skov
  • Jacob P Thyssen
  • BMJ Open.2020 Jul;10(7):e033801. bmjopen-2019-033801. doi: 10.1136/bmjopen-2019-033801.Epub 2020-07-12.

シリコンフォトニクス干渉計プラットフォーム上にCMOSプラズモニック変換器を用いた超高感度屈折率センサー

Ultra-sensitive refractive index sensor using CMOS plasmonic transducers on silicon photonic interferometric platform.
  • A Manolis
  • E Chatzianagnostou
  • G Dabos
  • D Ketzaki
  • B Chmielak
  • A L Giesecke
  • C Porschatis
  • P J Cegielski
  • S Suckow
  • L Markey
  • J-C Weeber
  • A Dereux
  • S Schrittwieser
  • R Heer
  • N Pleros
  • D Tsiokos
  • Opt Express.2020 Jul;28(14):20992-21001. 433138. doi: 10.1364/OE.383435.

ヘルスリテラシー、デジタルヘルスリテラシー、およびがん医療におけるデジタルヘルス技術の実施：戦略的アプローチの必要性

Health literacy, digital health literacy, and the implementation of digital health technologies in cancer care: the need for a strategic approach.
  • Emma Kemp
  • Joshua Trigg
  • Lisa Beatty
  • Chris Christensen
  • Haryana M Dhillon
  • Anthony Maeder
  • Patricia A H Williams
  • Bogda Koczwara
  • Health Promot J Austr.2020 Jul;doi: 10.1002/hpja.387.Epub 2020-07-18.

PSA-MIP受容体の結合親和性を利用したPSAのセンシングに向けた分子インプリントポリマーのキャビティ上での前立腺特異的抗原捕捉に基づく信頼性の高いバイオ分析法の開発新規バイオセンサー

Development of a reliable bioanalytical method based on prostate specific antigen trapping on the cavity of molecular imprinted polymer towards sensing of PSA using binding affinity of PSA-MIP receptor: A novel biosensor.
  • Leila Abbasy
  • Arezoo Mohammadzadeh
  • Mohammad Hasanzadeh
  • Nasrin Razmi
  • J Pharm Biomed Anal.2020 Jun;188:113447. S0731-7085(20)31333-9. doi: 10.1016/j.jpba.2020.113447.Epub 2020-06-26.

太平洋産カキ Crassostrea gigas の新規腫瘍壊死因子は、リゾチームと一酸化窒素の合成を誘発することで抗菌反応を媒介している

A novel tumor necrosis factor in the Pacific oyster Crassostrea gigas mediates the antibacterial response by triggering the synthesis of lysozyme and nitric oxide.
  • Yan Zheng
  • Zhaoqun Liu
  • Lingling Wang
  • Meijia Li
  • Yukun Zhang
  • Yanan Zong
  • Yinan Li
  • Linsheng Song
  • Fish Shellfish Immunol..2020 Mar;98:334-341. S1050-4648(19)31212-4. doi: 10.1016/j.fsi.2019.12.073.Epub 2019-12-24.

末梢血拡大における光顕微鏡法およびNested polymerase chain reaction（Nested PCR）法によるマラリアの検出とイラン南東部における18S rRNA遺伝子によるPlasmodium種の遺伝的多様性の調査を行った

Detection of malaria with light microscopy and Nested polymerase chain reaction (Nested PCR) methods in peripheral blood expansions and investigation of the genetic diversity of Plasmodium species by 18S rRNA gene in Southeast of Iran.
  • Ahmad Taghdiri
  • Pooya Ghasemi Nejad Almani
  • Iraj Sharifi
  • Mohammad Ali Mohammadi
  • Samira Salari
  • Microb. Pathog..2019 Dec;137:103782. S0882-4010(19)31107-6. doi: 10.1016/j.micpath.2019.103782.Epub 2019-10-07.

ビタミンD3はTRPC6とカルシウム・センシング・レセプターのアップレギュレーションに対抗することで、早期前立腺腫瘍のカルシウム誘発性進行を抑制する

Vitamin D3 Prevents Calcium-Induced Progression of Early-Stage Prostate Tumors by Counteracting TRPC6 and Calcium Sensing Receptor Upregulation.
  • Sophie Bernichtein
  • Natascha Pigat
  • Nicolas Barry Delongchamps
  • Florence Boutillon
  • Virginie Verkarre
  • Philippe Camparo
  • Edouard Reyes-Gomez
  • Arnaud Méjean
  • Stéphane M Oudard
  • Eve M Lepicard
  • Mélanie Viltard
  • Jean-Claude Souberbielle
  • Gérard Friedlander
  • Thierry Capiod
  • Vincent Goffin
  • Cancer Res..2017 01;77(2):355-365. 0008-5472.CAN-16-0687. doi: 10.1158/0008-5472.CAN-16-0687.Epub 2016-11-22.

ドコサヘキサエン酸（DHA）は、血管新生遺伝子やマイクロRNAの細胞内およびエクソソーム発現をダウンレギュレーションすることで、乳がん細胞のプロ血管新生作用を抑制します

Docosahexaenoic acid (DHA) inhibits pro-angiogenic effects of breast cancer cells via down-regulating cellular and exosomal expression of angiogenic genes and microRNAs.
  • Cynthia Aslan
  • Sepideh Maralbashi
  • Houman Kahroba
  • Milad Asadi
  • Mohammad Sadegh Soltani
  • Mahsa Javadian
  • Dariush Shanehbandi
  • Behzad Baradaran
  • Masood Darabi
  • Tohid Kazemi
  • Life Sci..2020 Jul;:118094. S0024-3205(20)30845-6. doi: 10.1016/j.lfs.2020.118094.Epub 2020-07-13.

腸内ファージ-細菌関連のメタゲノムデータは、病原体に対するファージ治療法の開発を支援する

Metagenome Data on Intestinal Phage-Bacteria Associations Aids the Development of Phage Therapy against Pathobionts.
  • Kosuke Fujimoto
  • Yasumasa Kimura
  • Masaki Shimohigoshi
  • Takeshi Satoh
  • Shintaro Sato
  • Georg Tremmel
  • Miho Uematsu
  • Yunosuke Kawaguchi
  • Yuki Usui
  • Yoshiko Nakano
  • Tetsuya Hayashi
  • Koji Kashima
  • Yoshikazu Yuki
  • Kiyoshi Yamaguchi
  • Yoichi Furukawa
  • Masanori Kakuta
  • Yutaka Akiyama
  • Rui Yamaguchi
  • Sheila E Crowe
  • Peter B Ernst
  • Satoru Miyano
  • Hiroshi Kiyono
  • Seiya Imoto
  • Satoshi Uematsu
  • Cell Host Microbe.2020 Jul;S1931-3128(20)30344-9. doi: 10.1016/j.chom.2020.06.005.Epub 2020-07-03.

アミロイド軽鎖（AL）アミロイドーシス患者における抗体可変遺伝子レパートリー破壊の多様なパターン

Diverse patterns of antibody variable gene repertoire disruption in patients with amyloid light chain (AL) amyloidosis.
  • Elaine C Chen
  • Samuel Rubinstein
  • Cinque Soto
  • Robin G Bombardi
  • Samuel B Day
  • Luke Myers
  • Alexey Zaytsev
  • Mahsa Majedi
  • R Frank Cornell
  • James E Crowe
  • PLoS ONE.2020;15(7):e0235713. PONE-D-20-09222. doi: 10.1371/journal.pone.0235713.Epub 2020-07-07.

(+)-リモネン・エポキシドの非臨床毒性と神経疾患に対する生理薬理学的特性

Non-clinical toxicity of (+)-limonene epoxide and its physio-pharmacological properties on neurological disorders.
  • Antonia Amanda Cardoso de Almeida
  • José Roberto de Oliveira Ferreira
  • Rusbene Bruno Fonseca de Carvalho
  • Marcia Dos Santos Rizzo
  • Luciano da Silva Lopes
  • Dalton Dittz
  • João Marcelo de Castro E Souza
  • Paulo Michel Pinheiro Ferreira
  • Naunyn Schmiedebergs Arch. Pharmacol..2020 Jul;10.1007/s00210-020-01943-w. doi: 10.1007/s00210-020-01943-w.Epub 2020-07-11.

生理的に関連性のある食品システムからのグルテン消化のプロテオミクスモデル。セリアック病に関与する小麦からの免疫原性ペプチドの消化に焦点を当てています

Proteomic modelling of gluten digestion from a physiologically relevant food system: A focus on the digestion of immunogenic peptides from wheat implicated in celiac disease.
  • Olivia Ogilvie
  • Sarah Roberts
  • Kevin Sutton
  • Laura Domigan
  • Nigel Larsen
  • Juliet Gerrard
  • Nicholas Demarais
  • Food Chem.2020 Jul;333:127466. S0308-8146(20)31328-5. doi: 10.1016/j.foodchem.2020.127466.Epub 2020-07-05.

癌に関連した静脈閉塞の血管内治療。ステント単独とステントと線状放射性シードストランドを併用した場合の有効性の比較

Endovascular Treatment of Cancer-Associated Venous Obstruction: Comparison of Efficacy Between Stent Alone and Stent Combined With Linear Radioactive Seeds Strand.
  • Bei Wu
  • Guowen Yin
  • Xu He
  • Guoping Chen
  • Boxiang Zhao
  • Jinhua Song
  • Jianping Gu
  • Vasc Endovascular Surg.2020 Jul;:1538574420939747. doi: 10.1177/1538574420939747.Epub 2020-07-17.

組換えヒト骨形態形成蛋白質-7と骨原性培地の併用は、ナノハイドロキシアパタイト/コラーゲン/ポリ（L-ラクチド）上に播種したヒト臍帯間葉系幹細胞の骨再生に理想的な相乗効果をもたらさない可能性があることが示唆された

Combined use of recombinant human bone morphogenetic protein-7 and osteogenic media may have no ideal synergistic effect on bone regeneration of human umbilical cord mesenchymal stem cells seeded on nano-hydroxyapatite/collagen/poly (L-lactide).
  • Lingling E
  • Tao Cheng
  • Chuanjie Li
  • Rong Zhang
  • Shuo Zhang
  • Hongchen Liu
  • Wenjie Zheng
  • Stem Cells Dev..2020 Jul;doi: 10.1089/scd.2020.0066.Epub 2020-07-16.

アフリカ先住民コホートにおけるエクソンORF15のデノボアセンブリーベース解析は、標準的な次世代シークエンシング（NGS）データ解析パイプラインの限界を克服する

De Novo Assembly-Based Analysis of Exon ORF15 in an Indigenous African Cohort Overcomes Limitations of a Standard Next-Generation Sequencing (NGS) Data Analysis Pipeline.
  • Jordi Maggi
  • Lisa Roberts
  • Samuel Koller
  • George Rebello
  • Wolfgang Berger
  • Rajkumar Ramesar
  • Genes (Basel).2020 Jul;11(7). E800. doi: 10.3390/genes11070800.Epub 2020-07-15.

2 型糖尿病患者に対するメトホルミンの個別化治療における 19 種類のファーマコゲノミクスバイオマーカーの適合性の評価

Evaluation of the suitability of 19 pharmacogenomics biomarkers for individualized metformin therapy for type 2 diabetes patients.
  • Lettilia Xhakaza
  • Zainonesa Abrahams-October
  • Brendon Pearce
  • Charity Mandisa Masilela
  • Oladele Vincent Adeniyi
  • Rabia Johnson
  • Joven Jebio Ongole
  • Mongi Benjeddou
  • Drug Metab Pers Ther.2020 Jun;35(2). /j/dmdi.2020.35.issue-2/dmpt-2020-0111/dmpt-2020-0111.xml. doi: 10.1515/dmpt-2020-0111.Epub 2020-06-30.

Plasmodium vivax Malariaは、ヨーロッパから駆除された原虫のレンズを通して見たマラリアです

Plasmodium vivax Malaria Viewed through the Lens of an Eradicated European Strain.
  • Lucy van Dorp
  • Pere Gelabert
  • Adrien Rieux
  • Marc de Manuel
  • Toni de-Dios
  • Shyam Gopalakrishnan
  • Christian Carøe
  • Marcela Sandoval-Velasco
  • Rosa Fregel
  • Iñigo Olalde
  • Raül Escosa
  • Carles Aranda
  • Silvie Huijben
  • Ivo Mueller
  • Tomàs Marquès-Bonet
  • François Balloux
  • M Thomas P Gilbert
  • Carles Lalueza-Fox
  • Mol. Biol. Evol..2020 03;37(3):773-785. 5614438. doi: 10.1093/molbev/msz264.

複数のプラスミドベクターが、中国の小売野菜から分離された拡張スペクトラム-β-ラクタマーゼ産生株の伝播を媒介する

Multiple Plasmid Vectors Mediate the Spread of in Extended-Spectrum-β-Lactamase-Producing Isolates from Retail Vegetables in China.
  • Luchao Lv
  • Xiuyu Huang
  • Jing Wang
  • Ying Huang
  • Xun Gao
  • Yiyun Liu
  • Qiaoli Zhou
  • Qianhui Zhang
  • Jun Yang
  • Jian-Ying Guo
  • Jian-Hua Liu
  • mSphere.2020 Jul;5(4). e00507-20. doi: 10.1128/mSphere.00507-20.Epub 2020-07-15.

本研究では、塩ストレス下でのソルガムやヒマワリのシュート乾物生産量を増加させることを目的としている

Different methods of silicon application attenuate salt stress in sorghum and sunflower by modifying the antioxidative defense mechanism.
  • Alexander Calero Hurtado
  • Denise Aparecida Chiconato
  • Renato de Mello Prado
  • Gilmar da Silveira Sousa Junior
  • Priscila Lupino Gratão
  • Guilherme Felisberto
  • Dilier Olivera Viciedo
  • Durvalina Maria Mathias Dos Santos
  • Ecotoxicol. Environ. Saf..2020 Jul;203:110964. S0147-6513(20)30803-4. doi: 10.1016/j.ecoenv.2020.110964.Epub 2020-07-15.

トレンティーノ・アルト・アディジェ地方（北イタリア）の林業労働者における E 型肝炎ウイルスの血清有病率

Seroprevalence of Hepatitis E Virus in Forestry Workers from Trentino-Alto Adige Region (Northern Italy).
  • Marina Monini
  • Fabio Ostanello
  • Alessandra Dominicis
  • Valentina Tagliapietra
  • Gabriele Vaccari
  • Annapaola Rizzoli
  • Claudia M Trombetta
  • Emanuele Montomoli
  • Ilaria Di Bartolo
  • Pathogens.2020 Jul;9(7). E568. doi: 10.3390/pathogens9070568.Epub 2020-07-14.

心不全患者の特徴と転帰を研究するための多国籍登録。グローバルうっ血性心不全（G-CHF）レジストリ

A multinational registry to study the characteristics and outcomes of heart failure patients: The global congestive heart failure (G-CHF) registry.
  • Philip Joseph
  • Hisham Dokainish
  • Tara McCready
  • Andrzej Budaj
  • Ambuj Roy
  • Georg Ertl
  • Juan Esteban Gomez-Mesa
  • Darryl Leong
  • Justin Ezekowitz
  • Camilla Hage
  • Fernando Lanas
  • Aldo P Maggioni
  • Karen Sliwa
  • Jun Zhu
  • Jean Rouleau
  • Kumar Balasubramanian
  • Salim Yusuf
  • Am. Heart J..2020 Jun;227:56-63. S0002-8703(20)30180-0. doi: 10.1016/j.ahj.2020.06.002.Epub 2020-06-06.

エクストラバージンオリーブオイルまたはヒマワリオイルを用いた高脂肪食後に得られたヒトトリグリセリドリッチリポ蛋白質で処理された内皮細胞のmiRNA/標的遺伝子プロファイル

miRNA/Target Gene Profile of Endothelial Cells Treated with Human Triglyceride-Rich Lipoproteins Obtained after a High-Fat Meal with Extra-Virgin Olive Oil or Sunflower Oil.
  • Concepción Santiago-Fernandez
  • Flores Martin-Reyes
  • Rocío Bautista
  • Mónica Tome
  • Josefa Gómez-Maldonado
  • Carolina Gutierrez-Repiso
  • Francisco J Tinahones
  • Eduardo Garcia-Fuentes
  • Lourdes Garrido-Sánchez
  • Mol Nutr Food Res.2020 Jul;:e2000221. doi: 10.1002/mnfr.202000221.Epub 2020-07-14.

2例の切除腫瘍（NET G1, NET G2）の吸引塗抹を用いた十二指腸ガストリノーマの悪性化の可能性を細胞病理学的に評価した。症例報告

Cytopathological evaluation of potential malignancy of duodenal gastrinoma using aspiration smears from two patients' resected tumors (NET G1, NET G2): A case report.
  • Hirotaka Noda
  • Kazuyoshi Masuda
  • Masami Kanbara
  • Hiromi Maeda
  • Tadao K Kobayashi
  • Chikao Yutani
  • Mol Clin Oncol.2020 Jun;12(6):592-596. MCO-0-0-2030. doi: 10.3892/mco.2020.2030.Epub 2020-04-10.

マトリックス剛性は、機械的に応答するEPHA2/LYN複合体を介して上皮-間葉系可塑性と腫瘍転移を制御している

Matrix Rigidity Controls Epithelial-Mesenchymal Plasticity and Tumor Metastasis via a Mechanoresponsive EPHA2/LYN Complex.
  • Laurent Fattet
  • Hae-Yun Jung
  • Mike W Matsumoto
  • Brandon E Aubol
  • Aditya Kumar
  • Joseph A Adams
  • Albert C Chen
  • Robert L Sah
  • Adam J Engler
  • Elena B Pasquale
  • Jing Yang
  • Dev. Cell.2020 Jun;S1534-5807(20)30420-2. doi: 10.1016/j.devcel.2020.05.031.Epub 2020-06-12.

上部尿路尿管癌の最終病理における病期と悪性度の予測における尿管鏡下生検の診断精度：システマティックレビューとメタアナリシス

Diagnostic accuracy of ureteroscopic biopsy in predicting stage and grade at final pathology in upper tract urothelial carcinoma: Systematic review and meta-analysis.
  • José Daniel Subiela
  • Angelo Territo
  • Asier Mercadé
  • Josep Balañà
  • Julia Aumatell
  • Julio Calderon
  • Andrea Gallioli
  • Daniel A González-Padilla
  • Josep Maria Gaya
  • Joan Palou
  • Alberto Breda
  • Eur J Surg Oncol.2020 Jul;S0748-7983(20)30548-5. doi: 10.1016/j.ejso.2020.06.024.Epub 2020-07-04.

誘導膜法により減少した骨移植片の吸収と体積変化に影響を与える因子.40人の患者における120回の連続CTスキャンの分析

Bone-Graft Resorption Reduced by the Induced Membrane Technique and Factors Affecting Volumetric Changes: An Analysis of 120 Serial Computed Tomographic Scans in 40 Patients.
  • Jae-Woo Cho
  • William T Kent
  • Chang-Wug Oh
  • Beom-Soo Kim
  • Won-Tae Cho
  • Jong-Keon Oh
  • J Bone Joint Surg Am.2020 Jul;102(14):1269-1278. 00004623-202007150-00017. doi: 10.2106/JBJS.19.00804.

患者由来間葉系間葉系間葉系細胞をTGFB1に曝露することで、小児急性巨核芽細胞性白血病モデルにおける線維化誘導が可能となった

Exposure of patient-derived mesenchymal stromal cells to TGFB1 supports fibrosis induction in a pediatric acute megakaryoblastic leukemia model.
  • Theresa Hack
  • Stefanie Bertram
  • Helen Blair
  • Verena Borger
  • Guntram Busche
  • Lora Denson
  • Enrico Fruth
  • Bernd Giebel
  • Olaf Heidenreich
  • Ludger Klein-Hitpass
  • Laxmikanth Kollipara
  • Stephanie Sendker
  • Albert Sickmann
  • Christiane Walter
  • Nils von Neuhoff
  • Helmut Hanenberg
  • Dirk Reinhardt
  • Markus Schneider
  • Mareike Rasche
  • Mol. Cancer Res..2020 Jul;molcanres.0091.2020. doi: 10.1158/1541-7786.MCR-20-0091.Epub 2020-07-08.

高悪性度狭窄症と高ホモシステイン血症を呈する頭蓋内狭窄症と高ホモシステイン血症が急性虚血性脳卒中に伴う皮質くも膜下出血を呈する若年男性

Intracranial High-Grade Stenosis and Hyperhomocysteinemia Presenting as Cortical Subarachnoid Hemorrhage Concomitant with Acute Ischemic Stroke in a Young Man.
  • Weiwei Qin
  • Weizheng Xie
  • Mingrong Xia
  • Robert Chunhua Zhao
  • Jiewen Zhang
  • Am J Case Rep.2020 Jun;21:e920606. 920606. doi: 10.12659/AJCR.920606.Epub 2020-06-24.

インドにおける小児 ICU 院内カンジダ症患者の特徴、転帰および死亡率の危険因子：多施設プロスペクティブ研究

Characteristics, outcome and risk factors for mortality of pediatric patients with ICU-acquired candidemia in India: a multicenter prospective study.
  • Arunaloke Chakrabarti
  • Prashant Sood
  • Shivaprakash M Rudramurthy
  • Sharon Chen
  • T Joseph Jillwin
  • Ranganathan Iyer
  • Ajanta Sharma
  • B N Harish
  • Indranil Roy
  • Anupma J Kindo
  • Deepinder Chhina
  • Jayanthi Savio
  • Deepak Mendiratta
  • Malini Capoor
  • Shukla Das
  • Anita Arora
  • Jagdish Chander
  • Immaculata Xess
  • B Appalaraju
  • Ujjwayini Ray
  • Ratna Rao
  • Vandana Kalwaje Eshwara
  • Sangeeta Joshi
  • Atul Patel
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  • Mycoses.2020 Jul;doi: 10.1111/myc.13145.Epub 2020-07-17.

上腕骨近位部骨折後遺症に対する治療後の低関節置換術生存率。北欧の関節形成術レジスター協会による3,245例の肩置換術

Low arthroplasty survival after treatment for proximal humerus fracture sequelae: 3,245 shoulder replacements from the Nordic Arthroplasty Register Association.
  • Ditte Unbehaun
  • Sigrid Rasmussen
  • Randi Hole
  • Anne Marie Fenstad
  • Björn Salomonsson
  • Yilmaz Demir
  • Steen Lund Jensen
  • Stig Brorson
  • Ville Äärimaa
  • Inger Mechlenburg
  • Jeppe Vejlgaard Rasmussen
  • Acta Orthop.2020 Jul;:1-6. doi: 10.1080/17453674.2020.1793548.Epub 2020-07-17.

p38マイトジェン活性化プロテインキナーゼが心臓のチャンバー特異的な周産期成長を制御している

p38 mitogen-activated protein kinase regulates chamber specific perinatal growth in heart.
  • Tomohiro Yokota
  • Jin Li
  • Jijun Huang
  • Zhaojun Xiong
  • Qing Zhang
  • Tracey W Chan
  • Yichen Ding
  • Christoph D Rau
  • Kevin Sung
  • Shuxun Ren
  • Rajan P Kulkarni
  • Tzung Hsiai
  • Xinshu Xiao
  • Marlin Touma
  • Susumu Minamisawa
  • Yibin Wang
  • J. Clin. Invest..2020 Jun;135859. doi: 10.1172/JCI135859.Epub 2020-06-23.

サイトカイニンは一酸化窒素を介してNostoc muscorumのサイパーメトリン毒性を緩和する。エキソ多糖の分泌制御、PS II光化学、活性酸素種の恒常性

Cytokinin alleviates cypermethrin toxicity in Nostoc muscorum by involving nitric oxide: Regulation of exopolysaccharides secretion, PS II photochemistry and reactive oxygen species homeostasis.
  • Santwana Tiwari
  • Nidhi Verma
  • Sheo Mohan Prasad
  • Vijay Pratap Singh
  • Chemosphere.2020 Jun;259:127356. S0045-6535(20)31549-6. doi: 10.1016/j.chemosphere.2020.127356.Epub 2020-06-14.

揮発性テルペノイド、ノルイソプレノイド、ベンゾイドは、コルヴィーナのブドウとワインの微細な規模のブドウ園のセグメンテーションのマーカーとして使用されています

Volatile terpenoids, norisoprenoids and benzenoids as markers of fine scale vineyard segmentation for Corvina grapes and wines.
  • Davide Slaghenaufi
  • Stefano Guardini
  • Riccardo Tedeschi
  • Maurizio Ugliano
  • Food Res. Int..2019 11;125:108507. S0963-9969(19)30378-3. doi: 10.1016/j.foodres.2019.108507.Epub 2019-06-24.

AKR1C2は、PI3K/AKTシグナル伝達経路を活性化することにより、食道扁平上皮癌の標的となる癌遺伝子として機能していることが明らかになった

AKR1C2 acts as a targetable oncogene in esophageal squamous cell carcinoma via activating PI3K/AKT signaling pathway.
  • Zhan-Fei Zhang
  • Tie-Jun Huang
  • Xin-Ke Zhang
  • Yu-Jie Xie
  • Si-Ting Lin
  • Fei-Fei Luo
  • Dong-Fang Meng
  • Hao Hu
  • Jing Wang
  • Li-Xia Peng
  • Chao-Nan Qian
  • Chao Cheng
  • Bi-Jun Huang
  • J. Cell. Mol. Med..2020 Jul;doi: 10.1111/jcmm.15604.Epub 2020-07-17.

ファビピラビル（T-705）のクリミア・コンゴ出血熱ウイルス感染症に対する効果

Efficacy of favipiravir (T-705) against Crimean-Congo hemorrhagic fever virus infection in cynomolgus macaques.
  • David W Hawman
  • Elaine Haddock
  • Kimberly Meade-White
  • Glenn Nardone
  • Friederike Feldmann
  • Patrick W Hanley
  • Jamie Lovaglio
  • Dana Scott
  • Takashi Komeno
  • Nozomi Nakajima
  • Yousuke Furuta
  • Brian B Gowen
  • Heinz Feldmann
  • Antiviral Res..2020 Jul;:104858. S0166-3542(20)30272-2. doi: 10.1016/j.antiviral.2020.104858.Epub 2020-07-06.

定期的なインスリン静注は、高品質の心臓 F-FDG PET 画像を得るための効率的かつ安全な方法である：非盲検、単施設、無作為化比較前向き試験

Intravenous regular insulin is an efficient and safe procedure for obtaining high-quality cardiac F-FDG PET images: an open-label, single-center, randomized controlled prospective trial.
  • Yang Chun Chen
  • Qing Qing Wang
  • Yue Hui Wang
  • Hui Lin Zhuo
  • Ruo Zhu Dai
  • J Nucl Cardiol.2020 Jun;10.1007/s12350-020-02219-9. doi: 10.1007/s12350-020-02219-9.Epub 2020-06-12.

経食道心エコーにおける催眠術。小児循環器科・先天性心疾患病棟での経験

[Hypnosis in transesophageal echocardiography. The experience in a Pediatric Cardiology and Congenital Heart Disease Unit].
  • Sabrina Montis
  • Danilo Sirigu
  • Andrea Marini
  • Alberto Lai
  • Piergiorgio Setti
  • Marco Camboni
  • Giovanni Carlo Mura
  • Michela Congia
  • Donatella Manca
  • Enrica Marini
  • Assunta Merola
  • Laura Orrù
  • Federica Scano
  • Ramona Stara
  • Monica Urru
  • Roberto Tumbarello
  • G Ital Cardiol (Rome).2019 Nov;20(11):651-657. doi: 10.1714/3254.32226.

2020年マーク・コベントリー賞。微生物由来の経口抗生物質は、慢性感染症に対する2期再置換人工股関節または膝関節形成術後のさらなる感染による失敗率を減少させる：最低2年間の多施設無作為化比較試験

2020 Mark Coventry Award: Microorganism-directed oral antibiotics reduce the rate of failure due to further infection after two-stage revision hip or knee arthroplasty for chronic infection: a multicentre randomized controlled trial at a minimum of two years.
  • JaeWon Yang
  • Javad Parvizi
  • Erik N Hansen
  • Chris N Culvern
  • John C Segreti
  • Timothy Tan
  • Curtis W Hartman
  • Scott M Sporer
  • Craig J Della Valle
  • Bone Joint J.2020 Jun;102-B(6_Supple_A):3-9. doi: 10.1302/0301-620X.102B6.BJJ-2019-1596.R1.

乾燥高温下で太陽光に曝露されたブドウ果実における揮発性化合物のメタボロームおよびトランスクリプトームの変化

Modulation of volatile compound metabolome and transcriptome in grape berries exposed to sunlight under dry-hot climate.
  • Lei He
  • Xiao-Qing Xu
  • Yu Wang
  • Wei-Kai Chen
  • Run-Ze Sun
  • Guo Cheng
  • Bin Liu
  • Wu Chen
  • Chang-Qing Duan
  • Jun Wang
  • Qiu-Hong Pan
  • BMC Plant Biol..2020 Feb;20(1):59. 10.1186/s12870-020-2268-y. doi: 10.1186/s12870-020-2268-y.Epub 2020-02-04.

薬物関連顎骨壊死症（MRONJ）の再建術後の組換えヒト骨形態形成蛋白質2/吸収性コラーゲンスポンジ（rhBMP-2/ACS）の再生効果

Regenerative effect of recombinant human bone morphogenetic protein-2/absorbable collagen sponge (rhBMP-2/ACS) after sequestrectomy of medication-related osteonecrosis of the jaw (MRONJ).
  • Song-Hee Min
  • No-Eul Kang
  • Seung-Il Song
  • Jeong-Keun Lee
  • J Korean Assoc Oral Maxillofac Surg.2020 Jun;46(3):191-196. jkaoms.2020.46.3.191. doi: 10.5125/jkaoms.2020.46.3.191.

多発性硬化症患者における 1 日 1 回および 2 回の経口疾患修飾薬への実際のアドヒアランスと持続性：システマティックレビューおよびメタアナリシス

Real-world adherence to, and persistence with, once- and twice-daily oral disease-modifying drugs in patients with multiple sclerosis: a systematic review and meta-analysis.
  • Jacqueline A Nicholas
  • Natalie C Edwards
  • Roger A Edwards
  • Anna Dellarole
  • Megan Grosso
  • Amy L Phillips
  • BMC Neurol.2020 Jul;20(1):281. 10.1186/s12883-020-01830-0. doi: 10.1186/s12883-020-01830-0.Epub 2020-07-14.

脳波における高振幅の高速活動：β-プロペラ蛋白質関連神経変性症（BPAN）の小児における早期診断マーカー

High-amplitude fast activity in EEG: An early diagnostic marker in children with beta-propeller protein-associated neurodegeneration (BPAN).
  • Hiroyuki Kidokoro
  • Hiroyuki Yamamoto
  • Tetsuo Kubota
  • Mitsuo Motobayashi
  • Yusaku Miyamoto
  • Tomohiko Nakata
  • Kyoko Takano
  • Naoko Shiba
  • Yu Okai
  • Masaharu Tanaka
  • Yoko Sakaguchi
  • Yuki Maki
  • Masahiro Kawaguchi
  • Takeshi Suzuki
  • Kazuhiro Muramatsu
  • Jun Natsume
  • Clin Neurophysiol.2020 Jun;131(9):2100-2104. S1388-2457(20)30371-0. doi: 10.1016/j.clinph.2020.06.006.Epub 2020-06-25.

BANCR発現レベルの上昇は、BRAFV600E突然変異の存在に応じて甲状腺乳頭がんの進行に異なる影響を及ぼす

Elevated BANCR expression levels have different effects on papillary thyroid carcinoma progression depending on the presence of the BRAFV600E mutation.
  • Stefana Stojanović
  • Sonja Šelemetjev
  • Ilona Đorić
  • Jelena Rončević
  • Jelena Janković Miljuš
  • Vladan Živaljević
  • Tijana Išić Denčić
  • Eur J Surg Oncol.2020 Jun;S0748-7983(20)30502-3. doi: 10.1016/j.ejso.2020.05.027.Epub 2020-06-18.

ウィルソン病による遅発性急性肝不全をプラスマフェレーシスと血液濾過で管理し、死亡ドナー肝移植の橋渡しに成功した症例報告と文献レビュー

Late-onset acute liver failure due to Wilson's disease managed by plasmapheresis and hemodiafiltration successfully serving as a bridge for deceased donor liver transplantation: a case report and literature review.
  • Akira Sukezaki
  • Po-Sung Chu
  • Masahiro Shinoda
  • Taizo Hibi
  • Nobuhito Taniki
  • Aya Yoshida
  • Miho Kawaida
  • Shutarou Hori
  • Rei Morikawa
  • Arata Kurokouchi
  • Shu Wakino
  • Kaori Kameyama
  • Hideaki Obara
  • Yuko Kitagawa
  • Hidetsugu Saito
  • Takanori Kanai
  • Nobuhiro Nakamoto
  • Clin J Gastroenterol.2020 Jul;10.1007/s12328-020-01175-8. doi: 10.1007/s12328-020-01175-8.Epub 2020-07-08.

慢性的なヒ素曝露は、雄性マウスの精子形成過程における精子のアクロソームと鞭毛形成の超微細構造と主要タンパク質の発現を損なうことで、精子の運動性を低下させた

Chronic arsenic exposure lowered sperm motility via impairing ultra-microstructure and key proteins expressions of sperm acrosome and flagellum formation during spermiogenesis in male mice.
  • Yongli Han
  • Chen Liang
  • Yuxiang Yu
  • Ram Kumar Manthari
  • Chenkai Cheng
  • Yanjia Tan
  • Xiang Li
  • Xiaolin Tian
  • Weixiang Fu
  • Jie Yang
  • Wei Yang
  • Yin Xing
  • Jundong Wang
  • Jianhai Zhang
  • Sci. Total Environ..2020 Sep;734:139233. S0048-9697(20)32750-9. doi: 10.1016/j.scitotenv.2020.139233.Epub 2020-05-19.

健康な閉経後女性を対象とした新規経口選択的エストロゲン受容体低下剤エラセストラントの薬物動態および薬力学的試験

Pharmacokinetic and Pharmacodynamic Studies of Elacestrant, A Novel Oral Selective Estrogen Receptor Degrader, in Healthy Post-Menopausal Women.
  • Maureen G Conlan
  • Erik F J de Vries
  • Awjm Glaudemans
  • Yamei Wang
  • Steven Troy
  • Eur J Drug Metab Pharmacokinet.2020 Jul;10.1007/s13318-020-00635-3. doi: 10.1007/s13318-020-00635-3.Epub 2020-07-13.

小児膀胱前立腺横紋筋肉腫に対するパルスドーズレートブラキセラピー。コンプライアンスと初期の臨床結果

Pulsed-dose rate brachytherapy for pediatric bladder prostate rhabdomyosarcoma: Compliance and early clinical results.
  • Cyrus Chargari
  • Hélène Martelli
  • Florent Guérin
  • Warren Bacorro
  • Guénolée de Lambert
  • Alexandre Escande
  • Véronique Minard-Colin
  • Isabelle Dumas
  • Eric Deutsch
  • Christine Haie-Meder
  • Radiother Oncol.2017 08;124(2):285-290. S0167-8140(17)32469-6. doi: 10.1016/j.radonc.2017.07.010.Epub 2017-07-28.

上顎におけるAll-on-4コンセプトを用いた4本インプラント維持型オーバーデンチャーとインプラント支持型固定補綴物の患者満足度、QOL、限界骨量の観点からの比較：2年間のレトロスペクティブ研究

Comparison of four-implant-retained overdentures and implant-supported fixed prostheses using the All-on-4 concept in the maxilla in terms of patient satisfaction, quality of life, and marginal bone loss: a 2-year retrospective study.
  • Emre Mumcu
  • Suleyman Cagatay Dayan
  • Emrah Genceli
  • Onur Geckili
  • Quintessence Int.2020;51(5):388-396. 44368. doi: 10.3290/j.qi.a44368.

カリウム摂取量の増加がレニン-アンジオテンシン-アルドステロン系および皮下抵抗性動脈に及ぼす影響：無作為化クロスオーバー試験

Effect of increased potassium intake on the renin-angiotensin-aldosterone system and subcutaneous resistance arteries: a randomized crossover study.
  • Rasmus Dreier
  • Bahareh Abdolalizadeh
  • Camilla L Asferg
  • Lisbet R Hölmich
  • Niels H Buus
  • Julie L Forman
  • Ulrik B Andersen
  • Martin Egfjord
  • Majid Sheykhzade
  • Jørgen L Jeppesen
  • Nephrol. Dial. Transplant..2020 Jun;gfaa114. doi: 10.1093/ndt/gfaa114.Epub 2020-06-29.

大伏在静脈移植による門脈再建における先天性門脈欠乏に対するリビングドナー肝移植術

Living donor liver transplantation for congenital absence of portal vein in portal venous reconstruction with a great saphenous vein graft.
  • Peilin Li
  • Masaaki Hidaka
  • Takashi Hamada
  • Satoshi Ikeda
  • Shinichiro Ono
  • Yasuhiro Maruya
  • Tota Kugiyama
  • Takanobu Hara
  • Tomoko Yoshimoto
  • Tomohiko Adachi
  • Takayuki Tanaka
  • Takayuki Miyoshi
  • Shunsuke Murakami
  • Yu Huang
  • Kengo Kanetaka
  • Susumu Eguchi
  • Surg Case Rep.2020 Jun;6(1):153. 10.1186/s40792-020-00916-8. doi: 10.1186/s40792-020-00916-8.Epub 2020-06-29.

SIOPE - 高精度放射線治療のための頭蓋骨ターゲットボリューム描出に関する脳腫瘍グループのコンセンサスガイドライン

SIOPE - Brain tumor group consensus guideline on craniospinal target volume delineation for high-precision radiotherapy.
  • Thankamma Ajithkumar
  • Gail Horan
  • Laetitia Padovani
  • Nicky Thorp
  • Beate Timmermann
  • Claire Alapetite
  • Lorenza Gandola
  • Monica Ramos
  • Karen Van Beek
  • Melissa Christiaens
  • Yasmin Lassen-Ramshad
  • Henriette Magelssen
  • Kristina Nilsson
  • Frank Saran
  • Barbara Rombi
  • Rolf Kortmann
  • Geert O Janssens
  • Radiother Oncol.2018 08;128(2):192-197. S0167-8140(18)30204-4. doi: 10.1016/j.radonc.2018.04.016.Epub 2018-05-02.

クエン酸塩蓄積症の診断には、単独での総カルシウム比はもはや有効ではない!この比率の有用性を強化するために、どのような追加パラメータを検討すべきか？

Total-to-ionized calcium ratio, taken alone, is no longer valid to diagnose citrate accumulation! What additional parameters should we consider to strengthen the utility of this ratio?
  • Patrick M Honore
  • Thomas Rimmelé
  • J Crit Care.2020 Jul;59:172-175. S0883-9441(20)30595-5. doi: 10.1016/j.jcrc.2020.06.009.Epub 2020-07-04.

輸入ネクタリンの木から新たなルテウイルスが検出された。入国後検疫におけるメタゲノミクスの導入を提案するためのケーススタディ

Detection of a New Luteovirus in Imported Nectarine Trees: A Case Study to Propose Adoption of Metagenomics in Post-Entry Quarantine.
  • Sudeep Bag
  • Maher Al Rwahnih
  • Ashley Li
  • Asaul Gonzalez
  • Adib Rowhani
  • Jerry K Uyemoto
  • Mysore R Sudarshana
  • Phytopathology.2015 Jun;105(6):840-6. doi: 10.1094/PHYTO-09-14-0262-R.Epub 2015-05-29.

生物学的および合成標的治療を受けたリウマチ性疾患患者におけるCOVID-19の臨床的特徴と転帰

Clinical features and outcomes of COVID-19 in patients with rheumatic diseases treated with biological and synthetic targeted therapies.
  • Carlos Sanchez-Piedra
  • Cesar Diaz-Torne
  • Javier Manero
  • José M Pego-Reigosa
  • Íñigo Rúa-Figueroa
  • Miguel A Gonzalez-Gay
  • Juan Gomez-Reino
  • Jose M Alvaro-Gracia
  • Ann. Rheum. Dis..2020 07;79(7):988-990. annrheumdis-2020-217948. doi: 10.1136/annrheumdis-2020-217948.Epub 2020-06-05.

腎移植臓器移植患者に対するビタミンK：血管硬化の調査（ViKTORIES）：無作為化比較試験の研究根拠とプロトコール

Vitamin K for kidney transplant organ recipients: investigating vessel stiffness (ViKTORIES): study rationale and protocol of a randomised controlled trial.
  • Jennifer Susan Lees
  • Kenneth Mangion
  • Elaine Rutherford
  • Miles D Witham
  • Rosemary Woodward
  • Giles Roditi
  • Tracey Hopkins
  • Katriona Brooksbank
  • Alan G Jardine
  • Patrick B Mark
  • Open Heart.2020 Jul;7(2). e001070. doi: 10.1136/openhrt-2019-001070.

Δ9-テトラヒドロカンナビノール（THC）ポストブドウ球菌性腸毒素B曝露の投与は、急性呼吸窮迫症候群と毒性からマウスを保護する

Administration of Δ9-Tetrahydrocannabinol (THC) Post-Staphylococcal Enterotoxin B Exposure Protects Mice From Acute Respiratory Distress Syndrome and Toxicity.
  • Amira Mohammed
  • Hasan Alghetaa
  • Muthanna Sultan
  • Narendra P Singh
  • Prakash Nagarkatti
  • Mitzi Nagarkatti
  • Front Pharmacol.2020;11:893. doi: 10.3389/fphar.2020.00893.Epub 2020-06-16.

標準的な接線放射線場では、乳腺内リンパ節への付随的なカバレッジは得られない

Standard Tangential Radiation Fields Do Not Provide Incidental Coverage to the Internal Mammary Nodes.
  • Gokoulakrichenane Loganadane
  • Megan Kassick
  • Benjamin H Kann
  • Melissa R Young
  • Christin A Knowlton
  • Suzanne B Evans
  • Susan A Higgins
  • Yazid Belkacemi
  • Mary Potenziani
  • Nicholas Saltmarsh
  • Lynn D Wilson
  • Meena S Moran
  • Pract Radiat Oncol.2020 Jan - Feb;10(1):21-28. S1879-8500(19)30226-7. doi: 10.1016/j.prro.2019.07.014.Epub 2019-08-05.

ゾレドロン酸逐次投与は、3年未満のデノスマブ治療の中止によるデメリットを回避できる可能性がある

Zoledronic acid sequential therapy could avoid disadvantages due to the discontinuation of less than 3-year denosumab treatment.
  • Hideomi Kondo
  • Nobukazu Okimoto
  • Toru Yoshioka
  • Shojiro Akahoshi
  • Yoshifumi Fuse
  • Takayuki Ogawa
  • Yuichi Okazaki
  • Yuji Katae
  • Manabu Tsukamoto
  • Yoshiaki Yamanaka
  • Makoto Kawasaki
  • Akinori Sakai
  • J. Bone Miner. Metab..2020 Jul;10.1007/s00774-020-01126-w. doi: 10.1007/s00774-020-01126-w.Epub 2020-07-12.

ジャガイモのアピラーゼの阻害に植物由来のカルコンのスクリーニング。健康における潜在的なタンパク質バイオテクノロジーのアプリケーション

Screening of plant derived chalcones on the inhibition of potato apyrase: Potential protein biotechnological applications in health.
  • Priscila Silva Grijó Farani
  • Danielle Gomes Marconato
  • Nayara Braga Emídio
  • Vinícius R D Pereira
  • Ismael J Alves Junior
  • Lígia S da Silveira
  • Mara R C Couri
  • Eveline Gomes Vasconcelos
  • William Castro Borges
  • Ademar Alves Silva Filho
  • Priscila de Faria-Pinto
  • Int. J. Biol. Macromol..2020 Jul;S0141-8130(20)33829-0. doi: 10.1016/j.ijbiomac.2020.07.081.Epub 2020-07-11.

集団遺伝学を用いて、大環状ラクトン抵抗性の状態と地域の両方に基づいてDirofilaria immitisの関連性を検討する

Using population genetics to examine relationships of Dirofilaria immitis based on both macrocyclic lactone-resistance status and geography.
  • Julie Sanchez
  • Guha Dharmarajan
  • Melissa M George
  • Cassan Pulaski
  • Adrian J Wolstenholme
  • John S Gilleard
  • Ray M Kaplan
  • Vet. Parasitol..2020 May;283:109125. S0304-4017(20)30105-9. doi: 10.1016/j.vetpar.2020.109125.Epub 2020-05-23.

前十字靭帯再建時のハムストリング自家移植のAllograft Augmentation of Hamstring Autograft Results in Equivalent Outcomes to Autograft Alone

Allograft Augmentation of Hamstring Autograft in Anterior Cruciate Ligament Reconstruction Results in Equivalent Outcomes to Autograft Alone.
  • Allison J Rao
  • David M Macknet
  • Casey R Stuhlman
  • Nicholas C Yeatts
  • David P Trofa
  • Susan M Odum
  • Bryan M Saltzman
  • James E Fleischli
  • Arthroscopy.2020 Jul;S0749-8063(20)30603-4. doi: 10.1016/j.arthro.2020.07.010.Epub 2020-07-14.

高尿酸血症を有する5/6腎摘出術モデルにおけるキサンチンオキシダーゼ阻害薬フェブキソスタットの心腎保護効果

Cardio-renal protective effect of the xanthine oxidase inhibitor febuxostat in the 5/6 nephrectomy model with hyperuricemia.
  • Hiroki Omizo
  • Yoshifuru Tamura
  • Chikayuki Morimoto
  • Masaki Ueno
  • Yuto Hayama
  • Emiko Kuribayashi-Okuma
  • Shunya Uchida
  • Shigeru Shibata
  • Sci Rep.2020 Jun;10(1):9326. 10.1038/s41598-020-65706-6. doi: 10.1038/s41598-020-65706-6.Epub 2020-06-09.

柑橘類の木におけるクロステロウイルス、バッドナウイルス、マンダリウイルスと黄龍ビン菌の同時検出のためのマルチプレックスポリメラーゼ連鎖反応法の開発（英文

Development of multiplex polymerase chain reaction assay for simultaneous detection of clostero-, badna- and mandari-viruses along with huanglongbing bacterium in citrus trees.
  • Ram Prasnna Meena
  • V K Baranwal
  • J. Virol. Methods.2016 09;235:58-64. S0166-0934(16)30251-8. doi: 10.1016/j.jviromet.2016.05.012.Epub 2016-05-18.

FZD10 抗体共役リポソームをベースとした制御された 5-FU 投与の大腸がん In vitro モデルでの有効性

Effectiveness of a Controlled 5-FU Delivery Based on FZD10 Antibody-Conjugated Liposomes in Colorectal Cancer In vitro Models.
  • Maria Principia Scavo
  • Annalisa Cutrignelli
  • Nicoletta Depalo
  • Elisabetta Fanizza
  • Valentino Laquintana
  • Giampietro Gasparini
  • Gianluigi Giannelli
  • Nunzio Denora
  • Pharmaceutics.2020 Jul;12(7). E650. doi: 10.3390/pharmaceutics12070650.Epub 2020-07-10.

免疫療法を受けた進行Nsclcにおける治療効果と生存率の予測因子としてのF-FDGペットパラメータとラジオミクス特徴の解析

F-FDG Pet Parameters and Radiomics Features Analysis in Advanced Nsclc Treated with Immunotherapy as Predictors of Therapy Response and Survival.
  • Giulia Polverari
  • Francesco Ceci
  • Valentina Bertaglia
  • Maria Lucia Reale
  • Osvaldo Rampado
  • Elena Gallio
  • Roberto Passera
  • Virginia Liberini
  • Paola Scapoli
  • Vincenzo Arena
  • Manuela Racca
  • Andrea Veltri
  • Silvia Novello
  • Désirée Deandreis
  • Cancers (Basel).2020 May;12(5). E1163. doi: 10.3390/cancers12051163.Epub 2020-05-05.

第9肋間静脈と第10肋間静脈を介したアジーゴス静脈への超音波ガイド下二重中心静脈アクセス

Ultrasound-guided double central venous access for azygos vein via the ninth and tenth intercostal veins.
  • Koichiro Yoshimaru
  • Toshiharu Matsuura
  • Yasuyuki Uchida
  • Keisuke Kajihara
  • Yukihiro Toriigahara
  • Yuki Kawano
  • Takuya Kondo
  • Yoshiaki Takahashi
  • Wakato Matsuoka
  • Noriyuki Kaku
  • Jun Maki
  • Tomoaki Taguchi
  • J Vasc Access.2020 Jun;:1129729820937133. doi: 10.1177/1129729820937133.Epub 2020-06-30.

近位部に多孔質コーティングを施したセメントレスの湾曲したショートステムの肩甲骨プロテーゼ：臨床的な相関関係を伴う2～5年後の放射線学的追跡調査でのイングロウ特性

Cementless curved short stem shoulder prostheses with a proximal porous coating: ingrowth properties at 2-5 years of radiological follow-up with clinical correlation.
  • Benjamin D Kleim
  • Christina Garving
  • Ulrich H Brunner
  • J Shoulder Elbow Surg.2020 Jun;S1058-2746(20)30236-6. doi: 10.1016/j.jse.2020.02.025.Epub 2020-06-09.

ブラジル・リオデジャネイロの献血者における抗SARS-CoV-2の血清有病率

Seroprevalence of anti-SARS-CoV-2 among blood donors in Rio de Janeiro, Brazil.
  • Luiz Amorim Filho
  • Célia Landmann Szwarcwald
  • Sheila de Oliveira Garcia Mateos
  • Antonio Carlos Monteiro Ponce de Leon
  • Roberto de Andrade Medronho
  • Valdiléa Gonçalves Veloso
  • Josiane Iole França Lopes
  • Luis Cristovão de Moraes Sobrino Porto
  • Alexandre Chieppe
  • Guilherme Loureiro Werneck
  • Rev Saude Publica.2020;54:69. S0034-89102020000100251. doi: 10.11606/s1518-8787.2020054002643.Epub 2020-07-06.

末梢性T細胞リンパ腫における自己幹細胞移植：血液CD34細胞のより良い動員は生存率の改善と関連している

Autologous stem cell transplantation in peripheral T-cell lymphoma: better mobilization of blood CD34 cells is associated with improved survival.
  • Anu Partanen
  • Antti Turunen
  • Jaakko Valtola
  • Marja Pyörälä
  • Kaija Vasala
  • Outi Kuittinen
  • Hanne Kuitunen
  • Karri Penttilä
  • Taru Kuittinen
  • Pentti Mäntymaa
  • Jukka Pelkonen
  • Ville Varmavuo
  • Esa Jantunen
  • Leuk. Lymphoma.2020 Jul;:1-3. doi: 10.1080/10428194.2020.1789629.Epub 2020-07-10.

グルタミン拮抗薬JHU-083は海馬の異常なグルタミナーゼ活性を正常化し、APOE4マウスの認知機能を改善する

Glutamine Antagonist JHU-083 Normalizes Aberrant Hippocampal Glutaminase Activity and Improves Cognition in APOE4 Mice.
  • Kristen R Hollinger
  • Xiaolei Zhu
  • Elizabeth S Khoury
  • Ajit G Thomas
  • Kevin Liaw
  • Carolyn Tallon
  • Ying Wu
  • Eva Prchalova
  • Atsushi Kamiya
  • Camilo Rojas
  • Sujatha Kannan
  • Barbara S Slusher
  • J. Alzheimers Dis..2020 Jul;JAD190588. doi: 10.3233/JAD-190588.Epub 2020-07-16.

製薬分野における溶融堆積モデリング（FDM）3Dプリンティングのエスカレーションについてのグラフィカルなレビュー

A graphical review on the escalation of fused deposition modeling (FDM) 3D printing in the pharmaceutical field.
  • Alice Melocchi
  • Marco Uboldi
  • Matteo Cerea
  • Anastasia Foppoli
  • Alessandra Maroni
  • Saliha Moutaharrik
  • Luca Palugan
  • Lucia Zema
  • Andrea Gazzaniga
  • J Pharm Sci.2020 Jul;S0022-3549(20)30377-4. doi: 10.1016/j.xphs.2020.07.011.Epub 2020-07-14.

顔面にきびを持つ被験者を対象としたクラスコテロン0.1%、0.5%、および1%の外用クリームを評価する第2b相、無作為化、二重盲検、車両対照、用量エスカレーション試験

A Phase 2b, Randomized, Double-Blind Vehicle Controlled, Dose Escalation Study Evaluating Clascoterone 0.1%, 0.5%, and 1% Topical Cream in Subjects With Facial Acne
  • Alessandro Mazzetti
  • Luigi Moro
  • Mara Gerloni
  • Martina Cartwright
  • J Drugs Dermatol.2019 Jun;18(6):570. S1545961619P0570X.

異なるタイプの病院で働く理学療法士・作業療法士におけるバーンアウト症候群と業務関連ストレス。どのグループが最も脆弱なのか？

Burnout Syndrome and Work-Related Stress in Physical and Occupational Therapists Working in Different Types of Hospitals: Which Group Is the Most Vulnerable?
  • Ju-Hyun Kim
  • Ae-Ryoung Kim
  • Myung-Gwan Kim
  • Chul-Hyun Kim
  • Ki-Hoon Lee
  • Donghwi Park
  • Jong-Moon Hwang
  • Int J Environ Res Public Health.2020 Jul;17(14). E5001. doi: 10.3390/ijerph17145001.Epub 2020-07-11.

生分解性ポリブチレンサクシネート及び非生分解性ポリ塩化ビニルマイクロプラスチックのアナモックス汚泥への影響性能評価,抑制効果,メタゲノム解析

Influence of biodegradable polybutylene succinate and non-biodegradable polyvinyl chloride microplastics on anammox sludge: Performance evaluation, suppression effect and metagenomic analysis.
  • Linqin Tang
  • Chengyuan Su
  • Yu Chen
  • Yunchuan Xian
  • Xinyue Hui
  • Ziyu Ye
  • Menglin Chen
  • Fenghua Zhu
  • He Zhong
  • J. Hazard. Mater..2020 Jun;401:123337. S0304-3894(20)31326-1. doi: 10.1016/j.jhazmat.2020.123337.Epub 2020-06-30.

スリランカにおける長い沈黙の後のメリオイドーシス：診断における環境的危険性とジレンマ、回復と13年間の長期追跡調査：症例報告

Melioidosis after a long silence in Sri Lanka: an environmental hazard and dilemma in diagnosis, with recovery and longitudinal follow-up for 13 years: a case report.
  • Manoji M K Pathirage
  • Senanayake A M Kularatne
  • Kosala G Weerakoon
  • J Med Case Rep.2020 Apr;14(1):50. 10.1186/s13256-020-02372-2. doi: 10.1186/s13256-020-02372-2.Epub 2020-04-18.

アデノウイルスベクターを用いた腫瘍新生血管新生へのターゲティングにより、播種性新生物病変に対する有効ながん遺伝子治療を実現する

Targeting Tumor Neoangiogenesis via Targeted Adenoviral Vector to Achieve Effective Cancer Gene Therapy for Disseminated Neoplastic Disease.
  • Myungeun Lee
  • Zhi Hong Lu
  • Jie Li
  • Elena A Kashentseva
  • Igor P Dmitriev
  • Samir A Mendonca
  • David T Curiel
  • Mol. Cancer Ther..2020 03;19(3):966-971. 1535-7163.MCT-19-0768. doi: 10.1158/1535-7163.MCT-19-0768.Epub 2020-01-06.

Agents Intervening against Delirium in the Intensive Care Unit Trial（AID-ICU試験）。詳細な統計解析計画

The Agents Intervening against Delirium in the Intensive Care Unit Trial (AID-ICU trial): A detailed statistical analysis plan.
  • Nina Andersen-Ranberg
  • Lone M Poulsen
  • Anders Perner
  • Jørn Wetterslev
  • Ole Mathiesen
  • Camilla B Mortensen
  • Stine Estrup
  • Bjørn H Ebdrup
  • Johanna Hästbacka
  • Giuseppe Citerio
  • Jesus Caballero
  • Matthew P G Morgan
  • Marie Oxenbøll-Collet
  • Sven-Olaf Weber
  • Anne Sofie Andreasen
  • Morten H Bestle
  • Helle B S Pedersen
  • Louise G Nielsen
  • Bülent Uslu
  • Troels B Jensen
  • Carsten Thee
  • Nilanjan Dey
  • Theis Lange
  • Acta Anaesthesiol Scand.2020 Jun;doi: 10.1111/aas.13661.Epub 2020-06-27.

近接-指数関数的ハイブリダイゼーション連鎖反応(PEHCR)とその応用による生細胞上の膜タンパク質-タンパク質相互作用の非破壊分析

A proximity-exponential hybridization chain reaction (PEHCR) and its application for nondestructive analysis of membrane protein-protein interactions on living cells.
  • Dongsheng Mao
  • Tianshu Chen
  • Xiaohao Liu
  • Lingjie Ren
  • Chang Feng
  • Guifang Chen
  • Anal. Chim. Acta.2020 Aug;1125:8-18. S0003-2670(20)30559-6. doi: 10.1016/j.aca.2020.05.024.Epub 2020-05-14.

うつ病リスクのある家族におけるうつ病症状の予測。後方脳波αと宗教・スピリチュアリティの相互関係

Predicting Depression Symptoms in Families at Risk for Depression: Interrelations of Posterior EEG Alpha and Religion/Spirituality.
  • Lidia Y X Panier
  • Gerard E Bruder
  • Connie Svob
  • Priya Wickramaratne
  • Marc J Gameroff
  • Myrna M Weissman
  • Craig E Tenke
  • Jürgen Kayser
  • J Affect Disord.2020 Sep;274:969-976. S0165-0327(20)30233-0. doi: 10.1016/j.jad.2020.05.084.Epub 2020-05-27.

トリパノソーマにおけるミトコンドリアRNA処理のレクシスと文法

Lexis and Grammar of Mitochondrial RNA Processing in Trypanosomes.
  • Inna Aphasizheva
  • Juan Alfonzo
  • Jason Carnes
  • Igor Cestari
  • Jorge Cruz-Reyes
  • H Ulrich Göringer
  • Stephen Hajduk
  • Julius Lukeš
  • Susan Madison-Antenucci
  • Dmitri A Maslov
  • Suzanne M McDermott
  • Torsten Ochsenreiter
  • Laurie K Read
  • Reza Salavati
  • Achim Schnaufer
  • André Schneider
  • Larry Simpson
  • Kenneth Stuart
  • Vyacheslav Yurchenko
  • Z Hong Zhou
  • Alena Zíková
  • Liye Zhang
  • Sara Zimmer
  • Ruslan Aphasizhev
  • Trends Parasitol..2020 Apr;36(4):337-355. S1471-4922(20)30016-7. doi: 10.1016/j.pt.2020.01.006.Epub 2020-02-28.

ベトナムのフルーツコウモリから分離された新規アルファヘルペスウイルスの特性評価

Characterization of a novel alphaherpesvirus isolated from the fruit bat , in Viet Nam.
  • Takuya Inagaki
  • Souichi Yamada
  • Hikaru Fujii
  • Tomoki Yoshikawa
  • Miho Shibamura
  • Shizuko Harada
  • Shuetsu Fukushi
  • Mai Quynh Le
  • Co Thach Nguyen
  • Thi Thu Thuy Nguyen
  • Thanh Thuy Nguyen
  • Thanh Thuy Nguyen
  • Van Tay Quach
  • Vu Dinh Thong
  • Kazuki Mori
  • Michihito Sasaki
  • Agus Setiyono
  • Ekowati Handharyani
  • Haruko Takeyama
  • Futoshi Hasebe
  • Masayuki Saijo
  • J. Virol..2020 Jul;JVI.00673-20. doi: 10.1128/JVI.00673-20.Epub 2020-07-15.

軟部組織肉腫の肝臓への転移。病院ベースのがん登録からの歴史的コホート研究

Metastases of soft tissue sarcoma to the liver: A Historical Cohort Study from a Hospital-based Cancer Registry.
  • Masanori Okamoto
  • Masatake Matsuoka
  • Tamotsu Soma
  • Ryuta Arai
  • Hidenori Kato
  • Toru Harabayashi
  • Hirohumi Adachi
  • Toshiki Shinohara
  • Tamotsu Sagawa
  • Noriaki Nishiyama
  • Toshikazu Nambu
  • Wataru Sakai
  • Hiroaki Suzuki
  • Hiroyuki Kato
  • Hiroaki Hiraga
  • Cancer Med.2020 Jul;doi: 10.1002/cam4.3304.Epub 2020-07-10.

心血管磁気共鳴画像上の右室機能の低下は、ファロー四徴症の子宮胎盤機能障害と関連している

Reduced right ventricular function on cardiovascular magnetic resonance imaging is associated with uteroplacental impairment in tetralogy of Fallot.
  • Anne S Siegmund
  • Tineke P Willems
  • Petronella G Pieper
  • Caterina M Bilardo
  • Thomas M Gorter
  • Berto J Bouma
  • Monique R M Jongbloed
  • Gertjan Tj Sieswerda
  • Jolien W Roos-Hesselink
  • Arie P J van Dijk
  • Dirk J van Veldhuisen
  • Michael G Dickinson
  • J Cardiovasc Magn Reson.2020 Jul;22(1):52. 10.1186/s12968-020-00645-9. doi: 10.1186/s12968-020-00645-9.Epub 2020-07-16.

非小児結節性大腸病変に対する水中内視鏡的粘膜切除術。将来性のあるシングルアームの研究

UNDERWATER ENDOSCOPIC MUCOSAL RESECTION FOR NON-PEDUNCULATED COLORECTAL LESIONS. A PROSPECTIVE SINGLE-ARM STUDY.
  • Luciano Lenz
  • Bruno Martins
  • Fabio Shiguehisa Kawaguti
  • Alexandre Tellian
  • Caterina Maria Pia Simoni Pennachi
  • Mauricio Sorbello
  • Carla Gusmon
  • Gustavo Andrade de Paulo
  • Ricardo Uemura
  • Sebastian Geiger
  • Marcelo Simas de Lima
  • Adriana Safatle-Ribeiro
  • Elisa Baba
  • Claudio Lyoiti Hashimoto
  • Fauze Maluf-Filho
  • Ulysses Ribeiro
  • Arq Gastroenterol.2020 Apr-Jun;57(2):193-197. S0004-28032020000200193. doi: 10.1590/S0004-2803.202000000-37.

α-リノレン酸は、ツイスト1発現を減衰させ、ツイスト1介在性上皮間葉転換を抑制することで、ヒトトリプルネガティブ乳がん細胞の遊走を阻害する

α-Linolenic acid inhibits the migration of human triple-negative breast cancer cells by attenuating twist1 expression and suppressing twist1-mediated epithelial-mesenchymal transition.
  • Shih-Chung Wang
  • Hai-Lun Sun
  • Yi-Hsuan Hsu
  • Shu-Hui Liu
  • Chong-Kuei Lii
  • Chia-Han Tsai
  • Kai-Li Liu
  • Chin-Shiu Huang
  • Chien-Chun Li
  • Biochem. Pharmacol..2020 Jul;:114152. S0006-2952(20)30388-9. doi: 10.1016/j.bcp.2020.114152.Epub 2020-07-14.

CpGをコーティングしたプルシアンブルーナノ粒子をベースとした光熱療法と抗CTLA-4免疫チェックポイント遮断を組み合わせることで、神経芽腫に対する強力な休薬効果が誘発された

CpG-coated Prussian blue nanoparticles-based photothermal therapy combined with anti-CTLA-4 immune checkpoint blockade triggers a robust abscopal effect against neuroblastoma.
  • Juliana Cano-Mejia
  • Anshi Shukla
  • Debbie K Ledezma
  • Erica Palmer
  • Alejandro Villagra
  • Rohan Fernandes
  • Transl Oncol.2020 Jul;13(10):100823. S1936-5233(20)30315-6. doi: 10.1016/j.tranon.2020.100823.Epub 2020-07-08.

殺乳酸菌Lactobacillus casei DK128のTヘルパー1型免疫応答の増強に対するアジュバント効果と正常マウスおよびCD4欠損マウスにおけるインフルエンザワクチン接種の有効性について検討した

Adjuvant effects of killed Lactobacillus casei DK128 on enhancing T helper type 1 immune responses and the efficacy of influenza vaccination in normal and CD4-deficient mice.
  • Yu-Jin Jung
  • Ki-Hye Kim
  • Eun-Ju Ko
  • Youri Lee
  • Min-Chul Kim
  • Young-Tae Lee
  • Cheol-Hyun Kim
  • Subbiah Jeeva
  • Bo Ryoung Park
  • Sang-Moo Kang
  • Vaccine.2020 Jul;S0264-410X(20)30878-1. doi: 10.1016/j.vaccine.2020.06.075.Epub 2020-07-13.

勃起不全高齢ラットを対象としたロサルタン投与による体細胞のアポトーシスと酸化ストレスの抑制による勃起機能の回復

Restoration of erectile function by suppression of corporal apoptosis and oxidative stress with losartan in aged rats with erectile dysfunction.
  • Yi Wang
  • Yamin Wang
  • Rong Cong
  • Ye Tian
  • Chen Chen
  • Yichun Wang
  • Qijie Zhang
  • Xiang Zhou
  • Chengjian Ji
  • Xianghu Meng
  • Ninghong Song
  • Andrology.2020 May;8(3):769-779. doi: 10.1111/andr.12757.Epub 2020-02-03.

大規模ゲノムアソシエーション解析により、複数の圃場環境下で縞さび病抵抗性を付与する原因遺伝子候補を同定した

A large-scale genomic association analysis identifies the candidate causal genes conferring stripe rust resistance under multiple field environments.
  • Jianhui Wu
  • Rui Yu
  • Haiying Wang
  • Cai'e Zhou
  • Shuo Huang
  • Hanxuan Jiao
  • Shizhou Yu
  • Xiaojun Nie
  • Qilin Wang
  • Shengjie Liu
  • Song Weining
  • R P Singh
  • Sridhar Bhavani
  • Zhensheng Kang
  • Dejun Han
  • Qingdong Zeng
  • Plant Biotechnol. J..2020 Jul;doi: 10.1111/pbi.13452.Epub 2020-07-17.

世界的な脳神経外科の不公平に対処するための研究文献と医療システムレベルの取り組みとの間の結束： スコーピングレビュー

Cohesion between Research Literature and Health System Level Efforts to Address Global Neurosurgical Inequity: a scoping review.
  • Edward I Ham
  • Jeongyoon Kim
  • Ulrick Sidney
  • Jean Wilguens Lartigue
  • Saksham Gupta
  • Ignatius N Esene
  • Kee B Park
  • World Neurosurg.2020 Jul;S1878-8750(20)31515-1. doi: 10.1016/j.wneu.2020.06.237.Epub 2020-07-13.

米国の民間保険者集団における原発性副甲状腺機能亢進症の未治療。手術ガイドラインの拡大にもかかわらず、副甲状腺摘出術の利用率が低下している

Undertreatment of primary hyperparathyroidism in a privately insured US population: Decreasing utilization of parathyroidectomy despite expanding surgical guidelines.
  • Carolyn D Seib
  • Tong Meng
  • Insoo Suh
  • Robin M Cisco
  • Dana T Lin
  • Arden M Morris
  • Amber W Trickey
  • Electron Kebebew
  • Surgery.2020 Jul;S0039-6060(20)30289-0. doi: 10.1016/j.surg.2020.04.066.Epub 2020-07-09.

アリサルタン・イソプロキシルは本態性高血圧患者の内皮機能と血管障害を改善する。本態性高血圧症患者におけるアリサルタン・イソプロキシルの血管内皮機能改善効果：単施設、オープンラベル、無作為化対照試験

Allisartan Isoproxil Improves Endothelial Function and Vascular Damage in Patients with Essential Hypertension: A Single-Center, Open-Label, Randomized Controlled Trial.
  • Gaoxing Zhang
  • Yongqiang Fan
  • Yumin Qiu
  • Zhe Zhou
  • Jianning Zhang
  • Zhichao Wang
  • Yuanya Liu
  • Xing Liu
  • Jun Tao
  • Adv Ther.2020 Aug;37(8):3551-3561. 10.1007/s12325-020-01413-y. doi: 10.1007/s12325-020-01413-y.Epub 2020-06-24.

大メコン亜地域における抗マラリア薬耐性の分子疫学：観察研究

Molecular epidemiology of resistance to antimalarial drugs in the Greater Mekong subregion: an observational study.
  • Mallika Imwong
  • Mehul Dhorda
  • Kyaw Myo Tun
  • Aung Myint Thu
  • Aung Pyae Phyo
  • Stephane Proux
  • Kanokon Suwannasin
  • Chanon Kunasol
  • Suttipat Srisutham
  • Jureeporn Duanguppama
  • Ranitha Vongpromek
  • Cholrawee Promnarate
  • Aungkana Saejeng
  • Nardlada Khantikul
  • Rungniran Sugaram
  • Supinya Thanapongpichat
  • Nongyao Sawangjaroen
  • Kreepol Sutawong
  • Kay Thwe Han
  • Ye Htut
  • Khin Linn
  • Aye Aye Win
  • Tin M Hlaing
  • Rob W van der Pluijm
  • Mayfong Mayxay
  • Tiengkham Pongvongsa
  • Koukeo Phommasone
  • Rupam Tripura
  • Thomas J Peto
  • Lorenz von Seidlein
  • Chea Nguon
  • Dysoley Lek
  • Xin Hui S Chan
  • Huy Rekol
  • Rithea Leang
  • Cheah Huch
  • Dominic P Kwiatkowski
  • Olivo Miotto
  • Elizabeth A Ashley
  • Myat Phone Kyaw
  • Sasithon Pukrittayakamee
  • Nicholas P J Day
  • Arjen M Dondorp
  • Frank M Smithuis
  • Francois H Nosten
  • Nicholas J White
  • Lancet Infect Dis.2020 Jul;S1473-3099(20)30228-0. doi: 10.1016/S1473-3099(20)30228-0.Epub 2020-07-14.

進行膵癌患者に対するナブパクリタキセル＋ゲムシタビン療法後のセカンドライン化学療法におけるS-1の有効性

Efficacy of S-1 in second-line chemotherapy after nab-paclitaxel plus gemcitabine for patients with advanced pancreatic cancer.
  • Kiyotsugu Iede
  • Terumasa Yamada
  • Ryo Kato
  • Masami Ueda
  • Yujiro Tsuda
  • Shinsuke Nakashima
  • Katsuya Ohta
  • Jin Matsuyama
  • Masakazu Ikenaga
  • Shusei Tominaga
  • Cancer Rep (Hoboken).2020 Apr;3(2):e1215. doi: 10.1002/cnr2.1215.Epub 2019-08-28.

シデナムコリアの基底性神経節脳炎の自己抗体バイオマーカーおよび溶連菌感染症に関連する小児自己免疫性神経精神疾患

Autoantibody Biomarkers for Basal Ganglia Encephalitis in Sydenham Chorea and Pediatric Autoimmune Neuropsychiatric Disorder Associated With Streptococcal Infections.
  • Jennifer L Chain
  • Kathy Alvarez
  • Adita Mascaro-Blanco
  • Sean Reim
  • Rebecca Bentley
  • Rebecca Hommer
  • Paul Grant
  • James F Leckman
  • Ivana Kawikova
  • Kyle Williams
  • Julie A Stoner
  • Susan E Swedo
  • Madeleine W Cunningham
  • Front Psychiatry.2020;11:564. doi: 10.3389/fpsyt.2020.00564.Epub 2020-06-24.

また、メタロチオネインの誘導時間の延長は、高齢化したトランスジェニック線虫におけるAßおよびα-シヌクレインの毒性に対抗する

Prolongation of metallothionein induction combats Aß and α-synuclein toxicity in aged transgenic Caenorhabditis elegans.
  • Dagmar Pretsch
  • Judith Maria Rollinger
  • Axel Schmid
  • Miroslav Genov
  • Teresa Wöhrer
  • Liselotte Krenn
  • Mark Moloney
  • Ameya Kasture
  • Thomas Hummel
  • Alexander Pretsch
  • Sci Rep.2020 Jul;10(1):11707. 10.1038/s41598-020-68561-7. doi: 10.1038/s41598-020-68561-7.Epub 2020-07-16.

抗生物質は進行大腸癌患者におけるオキサリプラチンベースの治療効果を改善するが、イリノテカンベースの治療効果は改善しない

Antibiotics Improve the Treatment Efficacy of Oxaliplatin-Based but Not Irinotecan-Based Therapy in Advanced Colorectal Cancer Patients.
  • Hiroo Imai
  • Ken Saijo
  • Keigo Komine
  • Yuya Yoshida
  • Keiju Sasaki
  • Asako Suzuki
  • Kota Ouchi
  • Masahiro Takahashi
  • Shin Takahashi
  • Hidekazu Shirota
  • Masanobu Takahashi
  • Chikashi Ishioka
  • J Oncol.2020;2020:1701326. doi: 10.1155/2020/1701326.Epub 2020-06-17.

I期の透明細胞腎細胞がんにおけるマイクロRNAプロファイルは、転移性疾患への進行を予測する

MicroRNA profile in stage I clear cell renal cell carcinoma predicts progression to metastatic disease.
  • Matthew J Moynihan
  • Travis B Sullivan
  • Eric Burks
  • Jared Schober
  • Marc Calabrese
  • Ariel Fredrick
  • Thomas Kalantzakos
  • Joshua Warrick
  • David Canes
  • Jay D Raman
  • Kimberly Rieger-Christ
  • Urol. Oncol..2020 Jun;S1078-1439(20)30210-6. doi: 10.1016/j.urolonc.2020.05.006.Epub 2020-06-10.

鈍目鯛（Megalobrama amblycephala）の肝細胞に対する酵母加水分解物の抗酸化能と免疫調節効果の評価

Evaluation of antioxidant capacity and immunomodulatory effects of yeast hydrolysates for hepatocytes of blunt snout bream (Megalobrama amblycephala).
  • Samad Rahimnejad
  • Xiang-Yang Yuan
  • Wen-Bin Liu
  • Guang-Zhen Jiang
  • Xiu-Fei Cao
  • Yong-Jun Dai
  • Cong-Cong Wang
  • Hesham Eed Desouky
  • Fish Shellfish Immunol..2020 Jun;S1050-4648(20)30441-1. doi: 10.1016/j.fsi.2020.06.019.Epub 2020-06-12.

抗血小板療法選択のためにジェノタイピングされた患者におけるCYP2C19遺伝子型データの再利用可能性の程度を評価する

Evaluating the extent of reusability of CYP2C19 genotype data among patients genotyped for antiplatelet therapy selection.
  • Amber L Beitelshees
  • James M Stevenson
  • Nihal El Rouby
  • Chrisly Dillon
  • Philip E Empey
  • Elliot M Fielstein
  • Julie A Johnson
  • Nita A Limdi
  • Henry H Ong
  • Francesco Franchi
  • Dominick P Angiolillo
  • Joshua F Peterson
  • Marc B Rosenman
  • Todd C Skaar
  • Sony Tuteja
  • Larisa H Cavallari
  • Genet. Med..2020 Jul;10.1038/s41436-020-0894-2. doi: 10.1038/s41436-020-0894-2.Epub 2020-07-17.

低用量の抗生物質の予防は，1 歳未満の尿路性器管奇形の小児における腸内マイクロバイオームの安定性に大きな影響を与えない．

Low-dose antibiotic prophylaxis has no significant impact on the stability of the intestinal microbiome in children with urogenital tract malformations under 1 year of age.
  • C Strasser
  • W Spindelboeck
  • K Kashofer
  • J Oswald
  • B Haid
  • J Pediatr Urol.2020 Jun;S1477-5131(20)30335-1. doi: 10.1016/j.jpurol.2020.05.165.Epub 2020-06-01.

フェナントリジン類似体の発見：ΔFosBホモ二量体およびΔFosB/JunDヘテロ二量体へのDNAの結合を阻害する新規な化学プローブとしてのフェナントリジン類似体の発見

Discovery of phenanthridine analogues as novel chemical probes disrupting the binding of DNA to ΔFosB homodimers and ΔFosB/JunD heterodimers.
  • Yi Li
  • Zhiqing Liu
  • Galina Aglyamova
  • Jianping Chen
  • Haiying Chen
  • Mukund Bhandari
  • Mark A White
  • Gabrielle Rudenko
  • Jia Zhou
  • Bioorg. Med. Chem. Lett..2020 Aug;30(16):127300. S0960-894X(20)30411-X. doi: 10.1016/j.bmcl.2020.127300.Epub 2020-06-06.

ゲムシタビンを含む第一選択療法に失敗した膵臓がん患者を対象に、5-フルオロウラシルおよびオキサリプラチンをベースとした第二選択療法で治療した場合の全生存期間を検討したメタアナリシス：パフォーマンスステータスの影響および他のレジメンとの比較

Meta-analysis examining overall survival in patients with pancreatic cancer treated with second-line 5-fluorouracil and oxaliplatin-based therapy after failing first-line gemcitabine-containing therapy: effect of performance status and comparison with other regimens.
  • Zev A Wainberg
  • Kynan Feeney
  • Myung Ah Lee
  • Andrés Muñoz
  • Antonio Cubillo Gracián
  • Sara Lonardi
  • Baek-Yeol Ryoo
  • Annie Hung
  • Yong Lin
  • Johanna Bendell
  • J Randolph Hecht
  • BMC Cancer.2020 Jul;20(1):633. 10.1186/s12885-020-07110-x. doi: 10.1186/s12885-020-07110-x.Epub 2020-07-08.

有毒ミクロシスティスは塩化物の増加に対するミジンコの耐性を低下させ、低塩化物は有毒ミクロシスティスによるミジンコへの害を緩和する

Toxic microcystis reduces tolerance of daphnia to increased chloride, and low chloride alleviates the harm of toxic microcystis to daphnia.
  • Yurou Li
  • Yuying Zhu
  • Lili Ma
  • Jing Huang
  • Yunfei Sun
  • Lu Zhang
  • Kai Lyu
  • Zhou Yang
  • Chemosphere.2020 Jul;260:127594. S0045-6535(20)31789-6. doi: 10.1016/j.chemosphere.2020.127594.Epub 2020-07-11.

また、ヘパラン硫酸をcRGDリガンドとBMP2と共固定化したバイオミメティックプラットフォームは、BMP2を介した骨形成分化を促進することを明らかにしました

Heparan sulfate co-immobilized with cRGD ligands and BMP2 on biomimetic platforms promotes BMP2-mediated osteogenic differentiation.
  • Julius Sefkow-Werner
  • Paul Machillot
  • Adria Sales
  • Elaine Castro-Ramirez
  • Melissa Degardin
  • Didier Boturyn
  • Elisabetta Ada Cavalcanti-Adam
  • Corinne Albiges-Rizo
  • Catherine Picart
  • Elisa Migliorini
  • Acta Biomater.2020 Jul;S1742-7061(20)30400-1. doi: 10.1016/j.actbio.2020.07.015.Epub 2020-07-13.

Ocimum gratissimum L.の精油と発光ダイオード（LED）ライトとの関連付けによる抗生物質耐性の変調

Modulation of antibiotic resistance by the essential oil of Ocimum gratissimum L. in association with light-emitting diodes (LED) lights.
  • Maria Karollyna do N Silva Leandro
  • Janaína E Rocha
  • Camila F Bezerra
  • Priscilla R Freitas
  • Jessica Horana F Feitosa
  • Viviane B Bezerra
  • Rizelle de O Barros
  • Livia Maria G Leandro
  • José Junior Dos S Aguiar
  • Paulo S Pereira
  • Marcela Christofoli
  • Jaime Ribeiro-Filho
  • Marcello Iriti
  • Henrique Douglas M Coutinho
  • Edinardo Fagner F Matias
  • Z. Naturforsch., C, J. Biosci..2020 Jul;/j/znc.ahead-of-print/znc-2020-0034/znc-2020-0034.xml. doi: 10.1515/znc-2020-0034.Epub 2020-07-06.

境界線および局所的に進行した切除不能膵癌に対する5-フルオロウラシル、ロイコボリン、イリノテカン、オキサリプラチンの導入後、手術と放射線治療の併用を行った単施設での経験

A Single-Institution Experience of Induction 5-Fluorouracil, Leucovorin, Irinotecan, and Oxaliplatin Followed by Surgery Versus Consolidative Radiation for Borderline and Locally Advanced Unresectable Pancreatic Cancer.
  • Michael Cecchini
  • Joseph A Miccio
  • Jay Pahade
  • Jill Lacy
  • Ronald R Salem
  • Skyler B Johnson
  • Adriana Blakaj
  • Stacey Stein
  • Jeremy S Kortmansky
  • Kimberly L Johung
  • Pancreas.2020 Aug;49(7):904-911. doi: 10.1097/MPA.0000000000001592.

中国の農村地域である玄威と福源における固体燃料燃焼による外気汚染の特性化

Characterization of outdoor air pollution from solid fuel combustion in Xuanwei and Fuyuan, a rural region of China.
  • Wei Hu
  • George Downward
  • Jason Y Y Wong
  • Boris Reiss
  • Nathaniel Rothman
  • Lützen Portengen
  • Jihua Li
  • Rena R Jones
  • Yunchao Huang
  • Kaiyun Yang
  • Ying Chen
  • Jun Xu
  • Jun He
  • Bryan Bassig
  • Wei Jie Seow
  • H Dean Hosgood
  • Linlin Zhang
  • Guoping Wu
  • Fusheng Wei
  • Roel Vermeulen
  • Qing Lan
  • Sci Rep.2020 Jul;10(1):11335. 10.1038/s41598-020-68229-2. doi: 10.1038/s41598-020-68229-2.Epub 2020-07-09.

原生動物である Paramecium caudatum と Ceriodaphnia silvestrii に対するカルボフランとジウロンの個別毒性と混合毒性

Individual and mixture toxicity of carbofuran and diuron to the protozoan Paramecium caudatum and the cladoceran Ceriodaphnia silvestrii.
  • Adrislaine S Mansano
  • Raquel A Moreira
  • Hugo C Dornfeld
  • Emanuela C Freitas
  • Eny M Vieira
  • Michiel A Daam
  • Odete Rocha
  • Mirna H R Seleghim
  • Ecotoxicol. Environ. Saf..2020 Sep;201:110829. S0147-6513(20)30668-0. doi: 10.1016/j.ecoenv.2020.110829.Epub 2020-06-09.

予後因子は KRAS 変異状態によって異なる。大腸肝転移に対する肝切除術後の予後グループを定義するための分類と回帰木モデル

Prognostic factors differ according to KRAS mutational status: A classification and regression tree model to define prognostic groups after hepatectomy for colorectal liver metastasis.
  • Amika Moro
  • Rittal Mehta
  • Diamantis I Tsilimigras
  • Kota Sahara
  • Anghela Z Paredes
  • Fabio Bagante
  • Alfredo Guglielmi
  • Sorin Alexandrescu
  • George A Poultsides
  • Kazunari Sasaki
  • Federico N Aucejo
  • Timothy M Pawlik
  • Surgery.2020 Jul;S0039-6060(20)30303-2. doi: 10.1016/j.surg.2020.05.019.Epub 2020-07-13.

血清キマーゼレベルは、入院している小児患者の重篤なデング熱の警告徴候および臨床的体液蓄積と相関していた

Serum chymase levels correlate with severe dengue warning signs and clinical fluid accumulation in hospitalized pediatric patients.
  • Abhay P S Rathore
  • Manouri Senanayake
  • Arjuna Salinda Athapathu
  • Sunethra Gunasena
  • Irantha Karunaratna
  • Wei Yee Leong
  • Ting Lim
  • Chinmay Kumar Mantri
  • Annelies Wilder-Smith
  • Ashley L St John
  • Sci Rep.2020 Jul;10(1):11856. 10.1038/s41598-020-68844-z. doi: 10.1038/s41598-020-68844-z.Epub 2020-07-16.

Trypanosoma brucei brucei由来のメタクラスパーゼ-2（MCA2）を標的としたリガンドの検証と、トリパノソーマ・コンゴレンセ由来のMCA5への応用の可能性を示した

Validation of ligands targeting metacaspase-2 (MCA2) from Trypanosoma brucei brucei and their application to MCA5 from T. congolense as possible trypanocides.
  • L E-A Eyssen
  • Theresa Ht Coetzer
  • J. Mol. Graph. Model..2020 Jun;97:107579. S1093-3263(19)30913-1. doi: 10.1016/j.jmgm.2020.107579.Epub 2020-03-06.

PU.1とSpi-Bを欠損したマウスにおけるヤヌスキナーゼ変異は、活性酸素誘起DNA損傷を介してB細胞白血病を駆動する

Janus Kinase mutations in mice lacking PU.1 and Spi-B drive B cell leukemia through reactive oxygen species-induced DNA damage.
  • Michelle Lim
  • Carolina R Batista
  • Bruno R de Oliveira
  • Rachel Creighton
  • Jacob Ferguson
  • Kurt Clemmer
  • Devon Knight
  • James Iansavitchous
  • Danish Mahmood
  • Mariano Avino
  • Rodney P DeKoter
  • Mol. Cell. Biol..2020 Jul;MCB.00189-20. doi: 10.1128/MCB.00189-20.Epub 2020-07-06.

ミエリンオリゴデンドロサイト糖タンパク質抗体と中枢神経系脱髄性疾患：トルコの第三次医療機関の経験

Myelin oligodendrocyte glycoprotein antibody associated central nervous system demyelinating disease: a tertiary center experience from Turkey.
  • Berin Inan
  • Rahsan Gocmen
  • Atay Vural
  • Ayse Ilksen Colpak
  • Edgar Meinl
  • Rana Karabudak
  • Asli Tuncer
  • Mult Scler Relat Disord.2020 Jul;44:102376. S2211-0348(20)30451-X. doi: 10.1016/j.msard.2020.102376.Epub 2020-07-04.

小児急性リンパ性白血病治療における6-チオグアニンの臨床的有効性と安全性。システマティックレビューとメタアナリシスのためのプロトコル

Clinical efficacy and safety of 6-thioguanine in the treatment of childhood acute lymphoblastic leukemia: A protocol for systematic review and meta-analysis.
  • Liang Chen
  • Huai-Xiu Yan
  • Xiao-Wei Liu
  • Wen-Xin Chen
  • Medicine (Baltimore).2020 May;99(18):e20082. 00005792-202005010-00054. doi: 10.1097/MD.0000000000020082.

イソニアジド誘発性肝障害におけるサイクリンG1、CAT-1、STAT3標的遺伝子の制御におけるMicroRNA-122、-125b、-106bのメチル化の関与

Involvement of methylation of MicroRNA-122, -125b and -106b in regulation of Cyclin G1, CAT-1 and STAT3 target genes in isoniazid-induced liver injury.
  • Yuhong Li
  • Qi Ren
  • Lingyan Zhu
  • Yingshu Li
  • Jinfeng Li
  • Yiyang Zhang
  • Guoying Zheng
  • Tiesheng Han
  • Shufeng Sun
  • Fumin Feng
  • BMC Pharmacol Toxicol.2018 03;19(1):11. 10.1186/s40360-018-0201-x. doi: 10.1186/s40360-018-0201-x.Epub 2018-03-20.

2014年欧州心臓病学会ガイドラインを用いた日本人の植込み型除細動器装着肥大型心筋症患者における治療法の予測

Predicting therapies in Japanese hypertrophic cardiomyopathy patients with an implantable cardioverter-defibrillator using the 2014 European Society of Cardiology guidelines.
  • Miyo Nakano
  • Yusuke Kondo
  • Masahiro Nakano
  • Takatsugu Kajiyama
  • Kazuo Miyazawa
  • Tomohiko Hayashi
  • Ryo Ito
  • Haruhiro Takahira
  • Yoshio Kobayashi
  • Heart Vessels.2020 Jul;10.1007/s00380-020-01668-z. doi: 10.1007/s00380-020-01668-z.Epub 2020-07-15.

強化された上室性頻拍識別器を用いた不適切な植え込み型除細動器治療の削減：ReduceIT試験

Reduction of inappropriate implantable cardioverter-defibrillator therapies using enhanced supraventricular tachycardia discriminators: the ReduceIT study.
  • Johann Christoph Geller
  • Armin Wöhrle
  • Mathias Busch
  • Albrecht Elsässer
  • Thomas Kleemann
  • Frank Birkenhauer
  • Peter Bramlage
  • Christian Veltmann
  • J Interv Card Electrophysiol.2020 Jul;10.1007/s10840-020-00816-9. doi: 10.1007/s10840-020-00816-9.Epub 2020-07-14.

COVID-19をはじめとする高伝染性患者のヘリコプターと固定翼航空救急車による搬送：スイスの航空救難レーガのナラティブレビューと経験

Transport of COVID-19 and other highly contagious patients by helicopter and fixed-wing air ambulance: a narrative review and experience of the Swiss air rescue Rega.
  • Roland Albrecht
  • Jürgen Knapp
  • Lorenz Theiler
  • Marcus Eder
  • Urs Pietsch
  • Scand J Trauma Resusc Emerg Med.2020 May;28(1):40. 10.1186/s13049-020-00734-9. doi: 10.1186/s13049-020-00734-9.Epub 2020-05-14.

前立腺癌微小環境における腫瘍関連マクロファージの増加は、インドネシアの患者コホートにおける患者の生存とアンドロゲン剥奪療法への反応を予測した

Increased tumor-associated macrophages in the prostate cancer microenvironment predicted patients' survival and responses to androgen deprivation therapies in Indonesian patients cohort.
  • Prahara Yuri
  • Katsumi Shigemura
  • Koichi Kitagawa
  • Exsa Hadibrata
  • Muhammad Risan
  • Andy Zulfiqqar
  • Indrawarman Soeroharjo
  • Ahmad Z Hendri
  • Raden Danarto
  • Aya Ishii
  • Saya Yamasaki
  • Yongmin Yan
  • Didik S Heriyanto
  • Masato Fujisawa
  • Prostate Int.2020 Jun;8(2):62-69. S2287-8882(20)30001-5. doi: 10.1016/j.prnil.2019.12.001.Epub 2020-02-10.

免疫不全に関連するワクチン由来のポリオウイルスに関する最新情報-世界各国、2018年7月～2019年12月

Update on Immunodeficiency-Associated Vaccine-Derived Polioviruses - Worldwide, July 2018-December 2019.
  • Grace Macklin
  • Ousmane M Diop
  • Asghar Humayun
  • Shohreh Shahmahmoodi
  • Zeinab A El-Sayed
  • Henda Triki
  • Gloria Rey
  • Tigran Avagyan
  • Varja Grabovac
  • Jaume Jorba
  • Noha Farag
  • Ondrej Mach
  • MMWR Morb. Mortal. Wkly. Rep..2020 Jul;69(28):913-917. doi: 10.15585/mmwr.mm6928a4.Epub 2020-07-17.

ヒト-感染症の臨床的・免疫学的特徴、新しい洞察 ホンジュラス、中米

Clinical and Immunological Features of Human -Infection, Novel Insights Honduras, Central America.
  • Wilfredo Sosa-Ochoa
  • Concepción Zúniga
  • Luis Fernando Chaves
  • Gabriela Venicia Araujo Flores
  • Carmen Maria Sandoval Pacheco
  • Vania Lúcia Ribeiro da Matta
  • Carlos Eduardo Pereira Corbett
  • Fernando Tobias Silveira
  • Marcia Dalastra Laurenti
  • Pathogens.2020 Jul;9(7). E554. doi: 10.3390/pathogens9070554.Epub 2020-07-10.

固定部分入れ歯を支持するアバットメントの有無にかかわらず、インプラント周囲の骨応答と軟組織の変化。3年間の前向き無作為化対照研究の結果

Bone Response and Soft Tissue Changes Around Implants With/Without Abutments Supporting Fixed Partial Dentures: Results From a 3-Year, Prospective, Randomized, Controlled Study.
  • Catharina Göthberg
  • Ulrika André
  • Kerstin Gröndahl
  • Peter Thomsen
  • Christer Slotte
  • Clin Implant Dent Relat Res.2016 Apr;18(2):309-22. doi: 10.1111/cid.12315.Epub 2015-03-19.

子宮頸管の成熟化に対するフォーリーとプロスタグランジンの併用とフォーリーとオキシトシンの併用：ネットワークメタアナリシス

Combination of Foley and prostaglandins versus Foley and oxytocin for cervical ripening: a network meta-analysis.
  • Lauren Orr
  • Keith Reisinger-Kindle
  • Amrita Roy
  • Lisa Levine
  • Katherine Connolly
  • Paul Visintainer
  • Corina N Schoen
  • Am. J. Obstet. Gynecol..2020 May;S0002-9378(20)30531-7. doi: 10.1016/j.ajog.2020.05.007.Epub 2020-05-07.

ガラクトース欠損IgA1特異的モノクローナル抗体を用いた腎病理学的解析は、原発性IgA腎症と二次性IgA腎症を鑑別するための強力なツールである

Renal pathological analysis using galactose-deficient IgA1-specific monoclonal antibody is a strong tool for differentiation of primary IgA nephropathy from secondary IgA nephropathy.
  • Mingfeng Lee
  • Hitoshi Suzuki
  • Rina Kato
  • Yusuke Fukao
  • Maiko Nakayama
  • Toshiki Kano
  • Yuko Makita
  • Yusuke Suzuki
  • CEN Case Rep.2020 Jul;10.1007/s13730-020-00508-3. doi: 10.1007/s13730-020-00508-3.Epub 2020-07-16.

前立腺癌リンパ節転移の検出のための横断的画像診断技術の比較：批判的レビュー

Comparison of cross-sectional imaging techniques for the detection of prostate cancer lymph node metastasis: a critical review.
  • Amir H Lebastchi
  • Nikhil Gupta
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  • Morand Piert
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  • Michael A Ahdoot
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  • Jonathan B Bloom
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ハウスダストダニは、侵害受容体-マスト細胞群を活性化し、2型皮膚炎症を促進する

House dust mites activate nociceptor-mast cell clusters to drive type 2 skin inflammation.
  • Nadine Serhan
  • Lilian Basso
  • Riccardo Sibilano
  • Camille Petitfils
  • James Meixiong
  • Chrystelle Bonnart
  • Laurent L Reber
  • Thomas Marichal
  • Philipp Starkl
  • Nicolas Cenac
  • Xinzhong Dong
  • Mindy Tsai
  • Stephen J Galli
  • Nicolas Gaudenzio
  • Nat. Immunol..2019 11;20(11):1435-1443. 10.1038/s41590-019-0493-z. doi: 10.1038/s41590-019-0493-z.Epub 2019-10-07.

レクチン経路へのMASP1の追加-ハンセン病関連パズル：遺伝子多型とタンパク質レベルからのヒント

Adding MASP1 to the lectin pathway-Leprosy association puzzle: Hints from gene polymorphisms and protein levels.
  • Hellen Weinschutz Mendes
  • Angelica Beate Winter Boldt
  • Ewalda von Rosen Seeling Stahlke
  • Jens Christian Jensenius
  • Steffen Thiel
  • Iara J Taborda Messias-Reason
  • PLoS Negl Trop Dis.2020 04;14(4):e0007534. PNTD-D-19-00912. doi: 10.1371/journal.pntd.0007534.Epub 2020-04-02.

エンザルタミドのみで進行した転移性去勢抵抗性前立腺がんの男性を対象に、エンザルタミドとペンブロリズマブを併用した第II相単群試験

A phase II single-arm study of pembrolizumab with enzalutamide in men with metastatic castration-resistant prostate cancer progressing on enzalutamide alone.
  • Julie N Graff
  • Tomasz M Beer
  • Joshi J Alumkal
  • Rachel E Slottke
  • William L Redmond
  • George V Thomas
  • Reid F Thompson
  • Mary A Wood
  • Yoshinobu Koguchi
  • Yiyi Chen
  • Emile Latour
  • Raymond C Bergan
  • Charles G Drake
  • Amy E Moran
  • J Immunother Cancer.2020 Jul;8(2). e000642. doi: 10.1136/jitc-2020-000642.

過剰なクロムへの出生前暴露は、胎児前ラットのセルトリ細胞におけるアンドロゲンと卵胞刺激ホルモン受容体の発現を調節する転写因子を減衰させる

Prenatal exposure to excess chromium attenuates transcription factors regulating expression of androgen and follicle stimulating hormone receptors in Sertoli cells of prepuberal rats.
  • Navaneethabalakrishnan Shobana
  • Mani Kathiresh Kumar
  • Ajit Kumar Navin
  • Mohammad Abdulkader Akbarsha
  • Mariajoseph Michael Aruldhas
  • Chem. Biol. Interact..2020 Jul;:109188. S0009-2797(19)32015-0. doi: 10.1016/j.cbi.2020.109188.Epub 2020-07-14.

新規非免疫抑制性フィンゴリモド誘導体であるOSU-2Sの犬における薬物動態と忍容性、およびマウスおよびラットのデータとの比較

Pharmacokinetics and Tolerability of the Novel Non-immunosuppressive Fingolimod Derivative, OSU-2S, in Dogs and Comparisons with Data in Mice and Rats.
  • Zhiliang Xie
  • Min Chen
  • Swagata Goswami
  • Rajes Mani
  • Dasheng Wang
  • Samuel K Kulp
  • Chris C Coss
  • Larry J Schaaf
  • Fengyu Cui
  • John C Byrd
  • Ryan N Jennings
  • Karsten K Schober
  • Carrie Freed
  • Stephanie Lewis
  • Raphael Malbrue
  • Natarajan Muthusamy
  • Chad Bennett
  • William C Kisseberth
  • Mitch A Phelps
  • AAPS J.2020 Jul;22(4):92. 10.1208/s12248-020-00474-9. doi: 10.1208/s12248-020-00474-9.Epub 2020-07-16.

塩分ストレス因子である塩化ナトリウムの塩化物に対する致死的および亜致死的影響

Lethal and sublethal effects of the saline stressor sodium chloride on Chironomus xanthus and Girardia tigrina.
  • Aline Silvestre Pereira Dornelas
  • Renato Almeida Sarmento
  • Grasiele Soares Cavallini
  • Rone da Silva Barbosa
  • Mayane Marques Vieira
  • Althiéris de Souza Saraiva
  • Maria D Bordalo
  • Amadeu M V M Soares
  • João L T Pestana
  • Environ Sci Pollut Res Int.2020 Jun;10.1007/s11356-020-09556-9. doi: 10.1007/s11356-020-09556-9.Epub 2020-06-16.

出生前のフタル酸ジ-（2-エチルヘキシル）フタル酸塩の母体暴露は、位相および性別に依存した方法で成体マウスの子孫の空間記憶に障害を与える

Prenatal di-(2-ethylhexyl) phthalate maternal exposure impairs the spatial memory of adult mouse offspring in a phase- and gender-dependent manner.
  • Ling-Li Zhao
  • Ru Shen
  • Cong-Cong Sun
  • Shan-Yu Zhang
  • Bo Wang
  • Mei-Fang Sun
  • De-Xiang Xu
  • Environ Sci Pollut Res Int.2020 Aug;27(22):28267-28275. 10.1007/s11356-020-09181-6. doi: 10.1007/s11356-020-09181-6.Epub 2020-05-15.

再発・転移性皮膚扁平上皮がんに対するペンブロリズマブ単剤療法：シングルアーム第II相試験（KEYNOTE-629）

Pembrolizumab Monotherapy for Recurrent or Metastatic Cutaneous Squamous Cell Carcinoma: A Single-Arm Phase II Trial (KEYNOTE-629).
  • Jean-Jacques Grob
  • Rene Gonzalez
  • Nicole Basset-Seguin
  • Olga Vornicova
  • Jacob Schachter
  • Abhishek Joshi
  • Nicolas Meyer
  • Florent Grange
  • Josep M Piulats
  • Jessica R Bauman
  • Pingye Zhang
  • Burak Gumuscu
  • Ramona F Swaby
  • Brett G M Hughes
  • J. Clin. Oncol..2020 Jul;:JCO1903054. doi: 10.1200/JCO.19.03054.Epub 2020-07-16.

鎖骨股関節骨折患者に対する中長大腿骨近位釘の臨床成績。70 歳以上の日本人患者コホートにおける予備調査

Clinical Outcome of Mid-Length Proximal Femoral Nail for Patients With Trochanteric Hip Fractures: Preliminary Investigation in a Japanese Cohort of Patients More Than 70 Years Old.
  • Tomohiro Matsumura
  • Tsuneari Takahashi
  • Mitsuharu Nakashima
  • Yoshiya Nibe
  • Katsushi Takeshita
  • Geriatr Orthop Surg Rehabil.2020;11:2151459320936444. 10.1177_2151459320936444. doi: 10.1177/2151459320936444.Epub 2020-06-24.

硝酸還元酵素遺伝子napCの自発的な変異は、異なる気候の地域で環境に優しい低NOを放出するアルファルファ根粒菌の出現を駆動する

Spontaneous Mutations in the Nitrate Reductase Gene napC Drive the Emergence of Eco-friendly Low-NO-Emitting Alfalfa Rhizobia in Regions with Different Climates.
  • Silvina Brambilla
  • Gabriela Soto
  • Ariel Odorizzi
  • Valeria Arolfo
  • Wayne McCormick
  • Emiliano Primo
  • Walter Giordano
  • Cintia Jozefkowicz
  • Nicolás Ayub
  • Microb. Ecol..2020 May;79(4):1044-1053. 10.1007/s00248-019-01473-w. doi: 10.1007/s00248-019-01473-w.Epub 2019-12-11.

トラマドールとタペンタドールの臨床用量の反復投与は、ウィスターラットの肝臓と腎毒性効果を引き起こす

Repeated Administration of Clinical Doses of Tramadol and Tapentadol Causes Hepato- and Nephrotoxic Effects in Wistar Rats.
  • Joana Barbosa
  • Juliana Faria
  • Fernanda Garcez
  • Sandra Leal
  • Luís Pedro Afonso
  • Ana Vanessa Nascimento
  • Roxana Moreira
  • Odília Queirós
  • Félix Carvalho
  • Ricardo Jorge Dinis-Oliveira
  • Pharmaceuticals (Basel).2020 Jul;13(7). E149. doi: 10.3390/ph13070149.Epub 2020-07-10.

小麦のオーキシン受容体TIR1がFusarium graminearumに対する防御をネガティブに制御していることが、メタボローム-トランスクリプトームと機能的特性の統合的解析により明らかになった

Integrated metabolo-transcriptomics and functional characterization reveals that the wheat auxin receptor TIR1 negatively regulates defense against Fusarium graminearum.
  • Peisen Su
  • Lanfei Zhao
  • Wen Li
  • Jinxiao Zhao
  • Jun Yan
  • Xin Ma
  • Anfei Li
  • Hongwei Wang
  • Lingrang Kong
  • J Integr Plant Biol.2020 Jul;doi: 10.1111/jipb.12992.Epub 2020-07-17.

以前に移植した経カテーテル肺弁の機能障害に対する経カテーテル再インターベンション後の転帰

Outcomes After Transcatheter Reintervention for Dysfunction of a Previously Implanted Transcatheter Pulmonary Valve.
  • Shabana Shahanavaz
  • Felix Berger
  • Thomas K Jones
  • Jacqueline Kreutzer
  • Julie A Vincent
  • Andreas Eicken
  • Lisa Bergersen
  • Jonathan J Rome
  • Evan Zahn
  • Lars Søndergaard
  • John P Cheatham
  • Shicheng Weng
  • David Balzer
  • Doff McElhinney
  • JACC Cardiovasc Interv.2020 Jul;13(13):1529-1540. S1936-8798(20)30823-2. doi: 10.1016/j.jcin.2020.03.035.

第一世代と最新世代のバイオセラミックシーラーのエンテロコッカス・フェカリスの除去に対する抗菌活性.腸球菌フェカリスの除去に対する第一世代と最新世代のバイオセラミックシーラーの抗菌活性: An

Antibacterial activity of first and latest generation bioceramic sealers on the elimination of enterococcus faecalis: An .
  • G Gallusi
  • V Campanella
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  • J. Biol. Regul. Homeost. Agents.2020 May-Jun;34(3 Suppl. 1):73-79. 9.

選択的レーザー溶融法で作製した頸部インプラントの圧縮軸荷重実験と数値シミュレーションの比較．

A Comparison of Experimental Compressive Axial Loading Testing with a Numerical Simulation of Topologically Optimized Cervical Implants Made by Selective Laser Melting.
  • Marek Schnitzer
  • Radovan Hudák
  • Peter Sedlačko
  • Viktória Rajťuková
  • Alena Findrik Balogová
  • Jozef Živčák
  • Tomáš Kula
  • Jozef Bocko
  • Miroslav Džupon
  • Gabriela Ižaríková
  • Michal Karásek
  • Vladimír Filip
  • Eleonóra Ivančová
  • Matej Šajty
  • Peter Szedlák
  • Andrej Somoš
  • J. Biotechnol..2020 Jul;S0168-1656(20)30185-1. doi: 10.1016/j.jbiotec.2020.07.010.Epub 2020-07-13.

安定した白斑患者における吸引水ぶくれ表皮移植後の炎症性色素沈着の予防に対する創傷被覆生体材料の有効性：in vitro生物活性調査を伴う評価者盲検対照臨床試験

Efficacy of a wound-dressing biomaterial on prevention of postinflammatory hyperpigmentation after suction blister epidermal grafting in stable vitiligo patients: a controlled assessor-blinded clinical study with in vitro bioactivity investigation.
  • Ziqi Liu
  • Min Jiang
  • Juemin Zhao
  • Qianqian Wang
  • Chengfeng Zhang
  • Min Gao
  • Ming Gu
  • Leihong Xiang
  • Arch. Dermatol. Res..2020 Feb;10.1007/s00403-020-02049-2. doi: 10.1007/s00403-020-02049-2.Epub 2020-02-27.

中国南東部の家禽および下痢患者から分離された種の分子特性と抗生物質耐性プロファイル 2017-2019

Molecular Characterization and Antibiotic Resistant Profiles of Species Isolated From Poultry and Diarrheal Patients in Southeastern China 2017-2019.
  • Leyi Zhang
  • Yi Li
  • Yongqiang Shao
  • Yuqin Hu
  • Huihuang Lou
  • Xiaonan Chen
  • Yuejin Wu
  • Lingling Mei
  • Biao Zhou
  • Xibin Zhang
  • Wenwu Yao
  • Lei Fang
  • Yanjun Zhang
  • Front Microbiol.2020;11:1244. doi: 10.3389/fmicb.2020.01244.Epub 2020-06-23.

エタノール滴下粉砕法.酸化カドミウムナノ粒子触媒を用いた1,3Dジオキソログ1ベンゾピラン-6-カルボン酸およびピリドピリミジン-7-カルボン酸の合成

Ethanol-Drop Grinding Approach: Cadmium Oxide Nanoparticles Catalyzed Synthesis of [1,3]Dioxolo[g][1]benzopyran-6-carboxylic Acids and Pyrido[d]pyrimidine-7-carboxylic Acids.
  • Saman Dahi-Azar
  • Shahrzad Abdolmohammadi
  • Javad Mokhtari
  • Comb. Chem. High Throughput Screen..2020 Jul;CCHTS-EPUB-108093. doi: 10.2174/1386207323666200712145041.Epub 2020-07-12.

β-エレメンは、7,12-ジメチルベンズ(a)アントラセン/12-O-テトラデカノイルフェノール-13-アセテート誘発皮膚発癌を抑制し、マウス皮膚モデルにおける NF-κB 関連シグナル伝達イベントを抑制します

β-Elemene inhibits 7,12-dimethylbenz(a)anthracene/12-O-tetradecanoylphorbol-13-acetate-induced skin tumorigenesis through suppression of NF-κB-associated signaling events in the mouse skin model.
  • Xing Hu
  • Liang Wang
  • Lili Zhang
  • Tao Zhang
  • J. Biochem. Mol. Toxicol..2020 Jul;:e22550. doi: 10.1002/jbt.22550.Epub 2020-07-14.

セレクトフルオでの１，２-ジヒドロピリジンの求電子的フッ素化によるフッ素化３，６-ジヒドロピリジンおよび２-（フルオロメチル）ピリジンの合成

Synthesis of Fluorinated 3,6-Dihydropyridines and 2-(Fluoromethyl)pyridines by Electrophilic Fluorination of 1,2-Dihydropyridines with Selectfluor.
  • Nadiia V Pikun
  • Arkadij Sobolev
  • Aiva Plotniece
  • Martins Rucins
  • Brigita Vigante
  • Marina Petrova
  • Ruslan Muhamadejev
  • Karlis Pajuste
  • Yuriy G Shermolovich
  • Molecules.2020 Jul;25(14). E3143. doi: 10.3390/molecules25143143.Epub 2020-07-09.

非対称型スーパーキャパシタデバイス用電池型正極としてのコバルトタングステン二セレン担持ニッケルフォーム：構造特性と容量特性に関する様々なMWSe（M=Ni, Cu, Zn, Mn）との比較

Cobalt-tungsten diselenide-supported nickel foam as a battery-type positive electrode for an asymmetric supercapacitor device: comparison with various MWSe (M = Ni, Cu, Zn, and Mn) on the structural and capacitance characteristics.
  • Mani Sakthivel
  • Settu Ramki
  • Shen-Ming Chen
  • Kuo-Chuan Ho
  • Nanoscale.2020 Jul;doi: 10.1039/d0nr02990d.Epub 2020-07-17.

ICU 患者における Covid-19 感染時の鉄代謝およびリンパ球の特徴：観察的コホート研究

Iron metabolism and lymphocyte characterisation during Covid-19 infection in ICU patients: an observational cohort study.
  • Giuliano Bolondi
  • Emanuele Russo
  • Emiliano Gamberini
  • Alessandro Circelli
  • Manlio Cosimo Claudio Meca
  • Etrusca Brogi
  • Lorenzo Viola
  • Luca Bissoni
  • Venerino Poletti
  • Vanni Agnoletti
  • World J Emerg Surg.2020 06;15(1):41. 10.1186/s13017-020-00323-2. doi: 10.1186/s13017-020-00323-2.Epub 2020-06-30.

ヒドロクロロチアジドを使用しているオーストラリアの高齢者における口唇扁平上皮癌および皮膚黒色腫のリスク：集団ベースの症例対照研究

Risk of squamous cell carcinoma of the lip and cutaneous melanoma in older Australians using hydrochlorothiazide: a population-based case-control study.
  • Benjamin Daniels
  • Sallie-Anne Pearson
  • Claire M Vajdic
  • Anton Pottegård
  • Nicholas A Buckley
  • Helga Zoega
  • Basic Clin. Pharmacol. Toxicol..2020 Jul;doi: 10.1111/bcpt.13463.Epub 2020-07-01.

トルコ産ヴァレリアナ・アリアリフォリアの化学組成と抗酸化力、細胞毒性、殺虫力

Chemical composition and antioxidant, cytotoxic, and insecticidal potential of Valeriana alliariifolia in Turkey.
  • Burcu Sen-Utsukarci
  • Turgut Taskin
  • Fatih Goger
  • Nurhayat Tabanca
  • Alden S Estep
  • Sonja M Kessler
  • Ozlem Akbal-Dagistan
  • Hilal Bardakci
  • Mine Kurkcuoglu
  • James Becnel
  • Alexandra Kiemer
  • Afife Mat
  • Arh Hig Rada Toksikol.2019 Sep;70(3):207-218. aiht-2019-70-3273. doi: 10.2478/aiht-2019-70-3273.

局所進行非小細胞肺癌患者における手術後誘導化学放射線療法の有用性と予後の改善

Feasibility and prognostic benefit of induction chemoradiotherapy followed by surgery in patients with locally advanced non-small cell lung cancer.
  • Masayuki Tanahashi
  • Hiroshi Niwa
  • Haruhiro Yukiue
  • Eriko Suzuki
  • Naoko Yoshii
  • Takuya Watanabe
  • Yasunori Kaminuma
  • Kensuke Chiba
  • Hiroyuki Tsuchida
  • Shogo Yobita
  • J Thorac Dis.2020 May;12(5):2644-2653. jtd-12-05-2644. doi: 10.21037/jtd.2020.03.17.

実践におけるイノベーション弁証法的行動療法-思春期の感情的問題解決のためのスキルトレーニング（DBT STEPS-A）：アイルランドの初等教育後の学校でのパイロット実施の評価

Innovations in Practice: Dialectical behaviour therapy - skills training for emotional problem solving for adolescents (DBT STEPS-A): evaluation of a pilot implementation in Irish post-primary schools.
  • Daniel Flynn
  • Mary Joyce
  • Mareike Weihrauch
  • Paul Corcoran
  • Child Adolesc Ment Health.2018 Nov;23(4):376-380. doi: 10.1111/camh.12284.Epub 2018-06-13.

比較トキシコゲノミクスデータベースを活用して、環境衛生に関する知識のギャップを埋める：大気汚染に起因する心血管疾患のテストケース

Leveraging the Comparative Toxicogenomics Database to fill in knowledge gaps for environmental health: a test case for air pollution-induced cardiovascular disease.
  • Allan Peter Davis
  • Thomas C Wiegers
  • Cynthia J Grondin
  • Robin J Johnson
  • Daniela Sciaky
  • Jolene Wiegers
  • Carolyn J Mattingly
  • Toxicol. Sci..2020 Jul;kfaa113. doi: 10.1093/toxsci/kfaa113.Epub 2020-07-14.

食道がんの手術を受けた患者における治癒の失敗：手術を受けた病院が治癒の見込みに影響を与える：全国規模のコホート研究

Failure to Cure in Patients Undergoing Surgery for Esophageal Carcinoma: Hospital of Surgery Influences Prospects for Cure: A Nation-wide Cohort Study.
  • Daan M Voeten
  • Leonie R van der Werf
  • Bas P L Wijnhoven
  • Richard van Hillegersberg
  • Mark I van Berge Henegouwen
  • Ann. Surg..2020 Jul;doi: 10.1097/SLA.0000000000004178.Epub 2020-07-09.

子宮筋腫と関連した有機リン酸エステル、フタル酸エステル、および代替可塑剤への曝露

Exposure to organophosphate esters, phthalates, and alternative plasticizers in association with uterine fibroids.
  • Gowoon Lee
  • Sunmi Kim
  • Michiel Bastiaensen
  • Govindan Malarvannan
  • Giulia Poma
  • Noelia Caballero Casero
  • Celine Gys
  • Adrian Covaci
  • Sunggyu Lee
  • Jae-Eun Lim
  • Sori Mok
  • Hyo-Bang Moon
  • Gyuyeon Choi
  • Kyungho Choi
  • Environ. Res..2020 Jul;189:109874. S0013-9351(20)30769-6. doi: 10.1016/j.envres.2020.109874.Epub 2020-07-09.

低用量の一酸化窒素合成酵素阻害薬L-NAMEをラットに投与すると，持続的な血液量の増加と塩化ナトリウムコトランスポーター活性に伴う塩分感受性が誘導される．

Low dose L-NAME induces salt sensitivity associated with sustained increased blood volume and sodium-chloride cotransporter activity in rodents.
  • Conghui Wang
  • Fumiko Kawakami-Mori
  • Lei Kang
  • Nobuhiro Ayuzawa
  • Sayoko Ogura
  • Suang Suang Koid
  • Latapati Reheman
  • Alimila Yeerbolati
  • Beibei Liu
  • Yutaka Yatomi
  • Xiangmei Chen
  • Toshiro Fujita
  • Tatsuo Shimosawa
  • Kidney Int..2020 Jun;S0085-2538(20)30703-1. doi: 10.1016/j.kint.2020.05.050.Epub 2020-06-24.

癌における部位特異的変異のモデル化と解析により、既知のホットスポットと推定される新規のホットスポットが同定され、文脈に基づく配列に起因するバイアスが検出される

Modeling and analysis of site-specific mutations in cancer identifies known plus putative novel hotspots and bias due to contextual sequences.
  • Victor Trevino
  • Comput Struct Biotechnol J.2020;18:1664-1675. S2001-0370(20)30311-1. doi: 10.1016/j.csbj.2020.06.022.Epub 2020-06-20.

ゲンタマイシン含有コラーゲンインプラントと血管外科手術における鼡径部創傷感染症。プロスペクティブ無作為化対照多施設試験

Gentamicin Containing Collagen Implants and Groin Wound Infections in Vascular Surgery: A Prospective Randomised Controlled Multicentre Trial.
  • Lina F Wübbeke
  • Bjorn Telgenkamp
  • Tiemen van Boxtel
  • Lars J J Bolt
  • Sabrina Houthoofd
  • Patrick W H E Vriens
  • Lee H Bouwman
  • Barend M E Mees
  • Jan Willem H C Daemen
  • Eur J Vasc Endovasc Surg.2020 04;59(4):635-641. S1078-5884(20)30055-1. doi: 10.1016/j.ejvs.2020.01.010.Epub 2020-02-21.

PHD3の損失は、骨格筋の運動能力と脂肪酸化を促進する

PHD3 Loss Promotes Exercise Capacity and Fat Oxidation in Skeletal Muscle.
  • Haejin Yoon
  • Jessica B Spinelli
  • Elma Zaganjor
  • Samantha J Wong
  • Natalie J German
  • Elizabeth C Randall
  • Afsah Dean
  • Allen Clermont
  • Joao A Paulo
  • Daniel Garcia
  • Hao Li
  • Olivia Rombold
  • Nathalie Y R Agar
  • Laurie J Goodyear
  • Reuben J Shaw
  • Steven P Gygi
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Measurement of differential cross sections and charge ratios for -channel single top quark production in proton-proton collisions at .
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  • F Pandolfi
  • R Paramatti
  • C Quaranta
  • S Rahatlou
  • C Rovelli
  • F Santanastasio
  • L Soffi
  • N Amapane
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  • M Arneodo
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  • A Cappati
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  • E Migliore
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  • L Pacher
  • N Pastrone
  • M Pelliccioni
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  • A Romero
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  • A Staiano
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  • G B Yu
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  • V Dudenas
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  • Z Zolkapli
  • J F Benitez
  • A Castaneda Hernandez
  • J A Murillo Quijada
  • L Valencia Palomo
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  • E De La Cruz-Burelo
  • I Heredia-De La Cruz
  • R Lopez-Fernandez
  • A Sanchez-Hernandez
  • S Carrillo Moreno
  • C Oropeza Barrera
  • M Ramirez-Garcia
  • F Vazquez Valencia
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  • I Pedraza
  • H A Salazar Ibarguen
  • C Uribe Estrada
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  • V Matveev
  • P Moisenz
  • V Palichik
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肝細胞がんの病理組織学的悪性度を予測するには、TACE後の体積機能的MR指標の変化が必要か？

Does the change in volumetric functional MR metrics post-TACE predict histopathologic grading of hepatocellular carcinoma?
  • Sanaz Ameli
  • Mohammadreza Shaghaghi
  • Mounes Aliyari Ghasabeh
  • Pallavi Pandey
  • Bita Hazhirkarzar
  • Roya Rezvani Habibabadi
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非レトロウイルス性内在性ウイルスエレメントは、アデスアエギプティ卵巣におけるコグネートウイルス複製を制限する

Non-retroviral Endogenous Viral Element Limits Cognate Virus Replication in Aedes aegypti Ovaries.
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  • Artem Baidaliuk
  • Pascal Miesen
  • Lionel Frangeul
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アーモンド、ドライブドウ、ドライクランベリーの摂取が持久力運動パフォーマンス、回復力、精神運動速度に及ぼす影響：無作為化比較試験のプロトコール

Effects of almond, dried grape and dried cranberry consumption on endurance exercise performance, recovery and psychomotor speed: protocol of a randomised controlled trial.
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  • Alison M Hill
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  • BMJ Open Sport Exerc Med.2019;5(1):e000560. bmjsem-2019-000560. doi: 10.1136/bmjsem-2019-000560.Epub 2019-08-07.

MLPAとDNAインデックスは小児B細胞性急性リンパ芽球性白血病の分子診断を改善する

MLPA and DNA index improve the molecular diagnosis of childhood B-cell acute lymphoblastic leukemia.
  • Chih-Hsiang Yu
  • Tze-Kang Lin
  • Shiann-Tarng Jou
  • Chien-Yu Lin
  • Kai-Hsin Lin
  • Meng-Yao Lu
  • Shu-Huey Chen
  • Chao-Neng Cheng
  • Kang-Hsi Wu
  • Shih-Chung Wang
  • Hsiu-Hao Chang
  • Meng-Ju Li
  • Yu-Ling Ni
  • Yi-Ning Su
  • Dong-Tsamn Lin
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  • Sci Rep.2020 Jul;10(1):11501. 10.1038/s41598-020-68311-9. doi: 10.1038/s41598-020-68311-9.Epub 2020-07-13.

ミャンマーの無症候性感染症における薬剤耐性マーカーと関連した遺伝的変異

Genetic Variations Associated with Drug Resistance Markers in Asymptomatic Infections in Myanmar.
  • Yan Zhao
  • Ziling Liu
  • Myat Thu Soe
  • Lin Wang
  • Than Naing Soe
  • Huanping Wei
  • Aye Than
  • Pyae Linn Aung
  • Yuling Li
  • Xuexing Zhang
  • Yubing Hu
  • Haichao Wei
  • Yangminghui Zhang
  • Jessica Burgess
  • Faiza A Siddiqui
  • Lynette Menezes
  • Qinghui Wang
  • Myat Phone Kyaw
  • Yaming Cao
  • Liwang Cui
  • Genes (Basel).2019 09;10(9). E692. doi: 10.3390/genes10090692.Epub 2019-09-09.

遺伝性びまん性胃癌の内視鏡サーベイランスにおける生検のマッピングにおけるシングルバイトとダブルバイトの比較：単施設無作為化試験

Single-bite versus double-bite technique for mapping biopsies during endoscopic surveillance for hereditary diffuse gastric cancer: a single-center, randomized trial.
  • Apostolos Pappas
  • Wei Keith Tan
  • William Waldock
  • Susan Richardson
  • Monika Tripathi
  • Wladyslaw Januszewicz
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  • Endoscopy.2020 Jul;doi: 10.1055/a-1201-3125.Epub 2020-07-17.

ECOG-ACRIN Cancer Research Group Trial E3311における口咽頭癌に対する経口腔手術を用いた新しい外科医の資格認定と品質保証プロセス

A novel surgeon credentialing and quality assurance process using transoral surgery for oropharyngeal cancer in ECOG-ACRIN Cancer Research Group Trial E3311.
  • Robert L Ferris
  • Yael Flamand
  • F Christopher Holsinger
  • Gregory S Weinstein
  • Harry Quon
  • Ranee Mehra
  • Joaquin J Garcia
  • Michael L Hinni
  • Neil D Gross
  • Erich M Sturgis
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  • Eduardo Méndez
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  • Michael E Kupferman
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  • Benjamin L Judson
  • Jeremy Richmon
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  • Rodrigo Bayon
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  • Enver Ozer
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  • Wayne M Koch
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  • Shuli Li
  • Elin R Sigurdson
  • Barbara Burtness
  • Oral Oncol..2020 Jul;110:104797. S1368-8375(20)30233-5. doi: 10.1016/j.oraloncology.2020.104797.Epub 2020-07-14.

ピラカンサ属の生物活性と健康増進効果：ファイトケミカルの可能性に迫る鍵となるアプローチ

Biological activities and health-promoting effects of Pyracantha genus: a key approach to the phytochemical's potential.
  • Javad Sharifi-Rad
  • Yasaman Taheri
  • Seyed Abdulmajid Ayatollahi
  • Nima Naderi
  • Nanjangud Venaktesh Anil Kumar
  • Niranjan Koirala
  • Sujan Khadka
  • Natallia Karazhan
  • Md Shahinozzaman
  • Surjit Sen
  • Krishnendu Acharya
  • Abhijit Dey
  • Miquel Martorell
  • Natália Martins
  • Cell. Mol. Biol. (Noisy-le-grand).2020 Jun;66(4):20-27. Epub 2020-06-25.

エピネフリンおよびノルエピネフリンの薬理学的血清濃度は、カンジダ・アルビカンスの成長速度、形態形成、ストレス耐性、および病原性に影響を与えない

Pharmacological serum concentrations of epinephrine and norepinephrine do not affect growth rate, morphogenesis, stress tolerance, and virulence of Candida albicans.
  • Sebastian Wurster
  • Sebastian Lyos
  • Nathaniel D Albert
  • Dimitrios P Kontoyiannis
  • Med. Mycol..2020 Jul;myaa060. doi: 10.1093/mmy/myaa060.Epub 2020-07-17.

健康な人を対象としたストレス誘発型メンタルタスク中の心拍変動特性のモニタリングを目的とした耳たぶに装着したワイヤレスBluetooth光電式センサの検証

Validation of a Wireless Bluetooth Photoplethysmography Sensor Used on the Earlobe for Monitoring Heart Rate Variability Features during a Stress-Inducing Mental Task in Healthy Individuals.
  • Bruno Correia
  • Nuno Dias
  • Patrício Costa
  • José Miguel Pêgo
  • Sensors (Basel).2020 Jul;20(14). E3905. doi: 10.3390/s20143905.Epub 2020-07-13.

成人胸膜感染症患者におけるRAPID臨床リスク予測スコアのプロスペクティブな検証：PILOT試験

Prospective validation of the RAPID clinical risk prediction score in adult patients with pleural infection: the PILOT study.
  • John P Corcoran
  • Ioannis Psallidas
  • Stephen Gerry
  • Francesco Piccolo
  • Coenraad F Koegelenberg
  • Tarek Saba
  • Cyrus Daneshvar
  • Ian Fairbairn
  • Richard Heinink
  • Alex West
  • Andrew E Stanton
  • Jayne Holme
  • Jack A Kastelik
  • Henry Steer
  • Nicola J Downer
  • Mohammed Haris
  • Emma H Baker
  • Caroline F Everett
  • Justin Pepperell
  • Thomas Bewick
  • Lonny Yarmus
  • Fabien Maldonado
  • Burhan Khan
  • Alan Hart-Thomas
  • Georgina Hands
  • Geoffrey Warwick
  • Duneesha De Fonseka
  • Maged Hassan
  • Mohammed Munavvar
  • Anur Guhan
  • Mitra Shahidi
  • Zara Pogson
  • Lee Dowson
  • Natalia D Popowicz
  • Judith Saba
  • Neil R Ward
  • Rob J Hallifax
  • Melissa Dobson
  • Rachel Shaw
  • Emma L Hedley
  • Assunta Sabia
  • Barbara Robinson
  • Gary S Collins
  • Helen E Davies
  • Ly-Mee Yu
  • Robert F Miller
  • Nick A Maskell
  • Najib M Rahman
  • Eur. Respir. J..2020 Jul;2000130. doi: 10.1183/13993003.00130-2020.Epub 2020-07-16.

周産期うつ病のスクリーニング結果が陽性の女性への紹介の取り込みと取り込みを高めるための介入の有効性：システマティックレビューとメタアナリシス

Uptake of referrals for women with positive perinatal depression screening results and the effectiveness of interventions to increase uptake: a systematic review and meta-analysis.
  • W Q Xue
  • K K Cheng
  • D Xu
  • X Jin
  • W J Gong
  • Epidemiol Psychiatr Sci.2020 Jul;29:e143. S2045796020000554. doi: 10.1017/S2045796020000554.Epub 2020-07-17.

スースーティフロントドスピネテール（Synallaxis frontalis Aves: Furnariidae）の多型。常染色体マクロ染色体のペリセントリックインバージョンによる染色体再配列の証拠

Polymorphism of Sooty-fronted Spinetail (Synallaxis frontalis Aves: Furnariidae): Evidence of chromosomal rearrangements by pericentric inversion in autosomal macrochromosomes.
  • Marcelo Santos de Souza
  • Suziane Alves Barcellos
  • Alice Lemos Costa
  • Rafael Kretschmer
  • Analía Del Valle Garnero
  • Ricardo José Gunski
  • Genet. Mol. Biol..2019 Jan-Mar;42(1):62-67. S1415-47572019000100062. doi: 10.1590/1678-4685-GMB-2018-0039.Epub 2019-03-11.

北アメリカ北東部の条件で栽培された「ハニークリスプ」リンゴの木に対する排除網の列カバーの影響。光合成と果実の品質への影響

Impact of Exclusion Netting Row Covers on 'Honeycrisp' Apple Trees Grown under Northeastern North American Conditions: Effects on Photosynthesis and Fruit Quality.
  • Gérald Chouinard
  • Jonathan Veilleux
  • Francine Pelletier
  • Mikael Larose
  • Vincent Philion
  • Valentin Joubert
  • Daniel Cormier
  • Insects.2019 Jul;10(7). E214. doi: 10.3390/insects10070214.Epub 2019-07-19.

5-ヒドロキシトリプタミントランスポーター遺伝子連結プロモーター領域多型と生涯早漏の感受性との関連性：1,604人の被験者を対象としたメタアナリシス

Association between 5-hydroxytryptamine transporter gene-linked promoter region polymorphism and the susceptibility of lifelong premature ejaculation: a meta-analysis involving 1,604 subjects.
  • Kechong Zhou
  • Yuxuan Song
  • Yi Lu
  • Yongjiao Yang
  • Xiao Wang
  • Kang Liu
  • Xiaoqiang Liu
  • Transl Androl Urol.2020 Jun;9(3):1394-1404. tau-09-03-1394. doi: 10.21037/tau.2020.03.39.

自然に発生するネコパルボウイルス感染症を持つ猫におけるクラスA CpGオリゴデオキシヌクレオチドによる治療。プロスペクティブ研究

Treatment with Class A CpG Oligodeoxynucleotides in Cats with Naturally Occurring Feline Parvovirus Infection: A Prospective Study.
  • Filippo Ferri
  • Federico Porporato
  • Francesco Rossi
  • Daniela Enache
  • Carolina Callegari
  • Gabriele Gerardi
  • Luigi M Coppola
  • Barbara Contiero
  • Chiara Crinò
  • Neda Ranjbar Kohan
  • Marina L Meli
  • Hans Lutz
  • Regina Hofmann-Lehmann
  • Eric Zini
  • Viruses.2020 Jun;12(6). E640. doi: 10.3390/v12060640.Epub 2020-06-12.

アジアでHIVとともに生きる乳児、小児、青年の標準化された死因を決定する

Determining standardized causes of death of infants, children, and adolescents living with HIV in Asia.
  • Annette H Sohn
  • Pagakrong Lumbiganon
  • Nia Kurniati
  • Keswadee Lapphra
  • Matthew Law
  • Viet C Do
  • Lam Van Nguyen
  • Khanh H Truong
  • Dewi K Wati
  • Pradthana Ounchanum
  • Thanyawee Puthanakit
  • Tavitiya Sudjaritruk
  • Penh S Ly
  • Nik K N Yusoff
  • Sieu M Fong
  • Thahira J Mohamed
  • Revathy Nallusamy
  • Nagalingaswaran Kumarasamy
  • Azar Kariminia
  • AIDS.2020 Aug;34(10):1527-1537. doi: 10.1097/QAD.0000000000002583.

エピガロカテキン-3-ガレート（EGCG）は、酸化ストレスと小胞体ストレスを抑制することで、メチルパラチオンによって誘発された細胞質の変形から卵母細胞を保護します

Epigallocatechin-3-gallate (EGCG) protects the oocytes from methyl parathion-induced cytoplasmic deformities by suppressing oxidative and endoplasmic reticulum stress.
  • Shweta Hegde
  • Keerthana Karunakar Poojary
  • Rhea Rasquinha
  • Daphne Norma Crasta
  • Divya Gopalan
  • Srinivas Mutalik
  • Sazada Siddiqui
  • Satish Kumar Adiga
  • Guruprasad Kalthur
  • Pestic Biochem Physiol.2020 Jul;167:104588. S0048-3575(20)30083-3. doi: 10.1016/j.pestbp.2020.104588.Epub 2020-04-20.

アピゲニンは、ラット心筋細胞におけるミトコンドリア/リソソソーム損傷と酸化ストレスの低減を介してリン化アルミニウム誘導細胞障害を抑制する

Apigenin attenuates Aluminum phosphide-induced cytotoxicity via reducing mitochondrial/Lysosomal damages and oxidative stress in rat Cardiomyocytes.
  • Asal Jahedsani
  • Saleh Khezri
  • Mahsa Ahangari
  • Saba Bakhshii
  • Ahmad Salimi
  • Pestic Biochem Physiol.2020 Jul;167:104585. S0048-3575(20)30080-8. doi: 10.1016/j.pestbp.2020.104585.Epub 2020-04-19.

バイオ）フォトニクスのための近赤外蛍光シリケートナノシートの剥離

Exfoliated near infrared fluorescent silicate nanosheets for (bio)photonics.
  • Gabriele Selvaggio
  • Alexey Chizhik
  • Robert Nißler
  • Llyas Kuhlemann
  • Daniel Meyer
  • Loan Vuong
  • Helen Preiß
  • Niklas Herrmann
  • Florian A Mann
  • Zhiyi Lv
  • Tabea A Oswald
  • Alexander Spreinat
  • Luise Erpenbeck
  • Jörg Großhans
  • Volker Karius
  • Andreas Janshoff
  • Juan Pablo Giraldo
  • Sebastian Kruss
  • Nat Commun.2020 03;11(1):1495. 10.1038/s41467-020-15299-5. doi: 10.1038/s41467-020-15299-5.Epub 2020-03-20.

制御された薬物送達のためのソラフェニブを負荷した脂質ポリマーハイブリッドナノ粒子のマイクロ流体作製と特性評価

Microfluidic fabrication and characterization of Sorafenib-loaded lipid-polymer hybrid nanoparticles for controlled drug delivery.
  • Nayab Tahir
  • Asadullah Madni
  • Wei Li
  • Alexandra Correia
  • Muhammad Muzamil Khan
  • Muhammad Abdur Rahim
  • Hélder A Santos
  • Int J Pharm.2020 May;581:119275. S0378-5173(20)30259-3. doi: 10.1016/j.ijpharm.2020.119275.Epub 2020-03-27.

シミュレーションCTの使用は、thesevere急性呼吸器症候群コロナウイルス2pandemicの間にacoronavirus疾患2019screeningツールとして

The use of simulation-CT's as acoronavirus disease 2019screening tool during thesevere acute respiratory syndrome coronavirus 2pandemic.
  • Daan Nevens
  • Charlotte Billiet
  • Reinhilde Weytjens
  • Ines Joye
  • Melanie Machiels
  • Ann Vermylen
  • Ibrahim Chiari
  • Ward Bauwens
  • Peter Vemeulen
  • Luc Dirix
  • Philippe Huget
  • Dirk Verellen
  • Piet Dirix
  • Paul Meijnders
  • Radiother Oncol.2020 Jul;S0167-8140(20)30399-6. doi: 10.1016/j.radonc.2020.07.006.Epub 2020-07-14.

インドネシアのHIV/HCV感染者を対象とした肝硬変確認のためのAPRIとFIB-4の診断性能について検討した

Diagnostic performance of APRI and FIB-4 for confirming cirrhosis in Indonesian HIV/HCV co-infected patients.
  • Evy Yunihastuti
  • Bramantya Wicaksana
  • Andrian Wiraguna
  • Ainum Jhariah Hidayah
  • Fhadilla Amelia
  • Veritea Natali
  • Alvina Widhani
  • Andri Sanityoso Sulaiman
  • Juferdy Kurniawan
  • BMC Infect. Dis..2020 May;20(1):372. 10.1186/s12879-020-05069-5. doi: 10.1186/s12879-020-05069-5.Epub 2020-05-25.

治療困難なAIDS患者およびHIV感染者で致死性・障害性の高い日和見感染症を有する患者を対象とした精密診断・治療戦略のための研究

A study for precision diagnosing and treatment strategies in difficult-to-treat AIDS cases and HIV-infected patients with highly fatal or highly disabling opportunistic infections.
  • Yao Li
  • Yan-Ming Zeng
  • Yan-Qiu Lu
  • Yuan-Yuan Qin
  • Yao-Kai Chen
  • Medicine (Baltimore).2020 May;99(20):e20146. 00005792-202005150-00045. doi: 10.1097/MD.0000000000020146.

光生体調節療法はメチルプレドニゾロンに代わるものであり、衝撃を受けた第三大臼歯の除去後の痛み、腫れ、三叉神経症を軽減することができるか？

Can Photobiomodulation Therapy Be an Alternative to Methylprednisolone in Reducing Pain, Swelling, and Trismus After Removal of Impacted Third Molars?
  • Erkan Feslihan
  • Cennet Neslihan Eroğlu
  • Photobiomodul Photomed Laser Surg.2019 Nov;37(11):700-705. doi: 10.1089/photob.2019.4696.Epub 2019-10-07.

ウシの腱、ウシの皮膚、および魚の皮膚タイプIコラーゲンからの工学的組織のサブおよび超分子X線特性評価

Sub- and Supramolecular X-Ray Characterization of Engineered Tissues from Equine Tendon, Bovine Dermis, and Fish Skin Type-I Collagen.
  • Alberta Terzi
  • Nunzia Gallo
  • Simona Bettini
  • Teresa Sibillano
  • Davide Altamura
  • Marta Madaghiele
  • Liberato De Caro
  • Ludovico Valli
  • Luca Salvatore
  • Alessandro Sannino
  • Cinzia Giannini
  • Macromol Biosci.2020 May;20(5):e2000017. doi: 10.1002/mabi.202000017.Epub 2020-03-12.

アプタマーを用いた分離法を組み合わせた新規ラテラルフローバイオセンサーの開発.ハタの神経壊死ウイルスの迅速検出への応用

Development of a Novel Lateral Flow Biosensor Combined With Aptamer-Based Isolation: Application for Rapid Detection of Grouper Nervous Necrosis Virus.
  • Jiaxin Liu
  • Qiwei Qin
  • Xinyue Zhang
  • Chen Li
  • Yepin Yu
  • Xiaohong Huang
  • Omar Mukama
  • Lingwen Zeng
  • Shaowen Wang
  • Front Microbiol.2020;11:886. doi: 10.3389/fmicb.2020.00886.Epub 2020-05-19.

局所進行乳癌におけるネオアジュバント化学放射線療法とパクリタキセルの併用による病理学的完全奏効率の研究

Study of pathological complete response rate with neoadjuvant concurrent chemoradiation with paclitaxel in locally advanced breast cancer.
  • Priya Iyer
  • Venkatraman Radhakrishnan
  • Ananthi Balasubramanian
  • V Sridevi
  • Arvind Krishnamurthy
  • Manikandan Dhanushkodi
  • Shirley Sundersingh
  • Selvaluxmy Ganesarajah
  • Indian J Cancer.2020 Jul;289209. doi: 10.4103/ijc.IJC_524_19.Epub 2020-07-08.

サルコイドーシスにおけるCA-125上昇を伴う大量心嚢液貯留と胸部リンパ節腫脹：1例の報告

Massive pericardial effusion causing cardiac tamponade accompanied by elevated CA-125 and thoracic lymphadenopathy in sarcoidosis: a case report.
  • Taalaibek Kudaiberdiev
  • Elmira Tukusheva
  • Zhanybek Gaibyldaev
  • Gulnaz Tursunbekova
  • Zhunus Kadyraliev
  • Irina Akhmedova
  • Nurjan Tulopbergenov
  • Emil Muraliev
  • Int J Surg Case Rep.2020 Jun;72:355-360. S2210-2612(20)30440-5. doi: 10.1016/j.ijscr.2020.06.037.Epub 2020-06-13.

ユーイング肉腫を含む難治性/再発固形癌の小児および青年を対象としたタラゾパリブとテモゾロミドの併用療法の第 1/2 相試験。A Children's Oncology Group フェーズ 1 コンソーシアム試験（ADVL1411）

Phase 1/2 trial of talazoparib in combination with temozolomide in children and adolescents with refractory/recurrent solid tumors including Ewing sarcoma: A Children's Oncology Group Phase 1 Consortium study (ADVL1411).
  • Eric S Schafer
  • Rachel E Rau
  • Stacey L Berg
  • Xiaowei Liu
  • Charles G Minard
  • Alexander J R Bishop
  • J Carolina Romero
  • M John Hicks
  • Marvin D Nelson
  • Stephan Voss
  • Joel M Reid
  • Elizabeth Fox
  • Brenda J Weigel
  • Susan M Blaney
  • Pediatr Blood Cancer.2020 02;67(2):e28073. doi: 10.1002/pbc.28073.Epub 2019-11-14.

BIONIKK：ナイーブ転移性腎癌を対象としたニボルマブとイピリムマブまたはVEGFRチロシンキナーゼ阻害剤（TKI）による第2相バイオマーカー主導治験

BIONIKK: A phase 2 biomarker driven trial with nivolumab and ipilimumab or VEGFR tyrosine kinase inhibitor (TKI) in naïve metastatic kidney cancer.
  • Nicolas Epaillard
  • Audrey Simonaggio
  • Reza Elaidi
  • Fouzia Azzouz
  • Elena Braychenko
  • Constance Thibault
  • Cheng-Ming Sun
  • Marco Moreira
  • Stéphane Oudard
  • Yann-Alexandre Vano
  • Bull Cancer.2020 Jun;107(5S):eS22-eS27. S0007-4551(20)30283-6. doi: 10.1016/S0007-4551(20)30283-6.

全血中の毒性学的に関連する汚染物質360種のバイオモニタリングのための分析法の検証と検証に関するサポートデータセット

Supporting dataset on the validation and verification of the analytical method for the biomonitoring of 360 toxicologically relevant pollutants in whole blood.
  • Cristian Rial-Berriel
  • Andrea Acosta-Dacal
  • Fernando González
  • Natalia Pastor-Tiburón
  • Manuel Zumbado
  • Octavio P Luzardo
  • Data Brief.2020 Aug;31:105878. S2352-3409(20)30772-1. doi: 10.1016/j.dib.2020.105878.Epub 2020-06-18.

熟成茶園における土壌病は、茶園における植物ポリフェノール蓄積の結果として微生物群集のシフトと関連している

Soil Sickness in Aged Tea Plantation Is Associated With a Shift in Microbial Communities as a Result of Plant Polyphenol Accumulation in the Tea Gardens.
  • Yasir Arafat
  • Israr Ud Din
  • Muhammad Tayyab
  • Yuhang Jiang
  • Ting Chen
  • Zhaoying Cai
  • Hanyu Zhao
  • Xiangmin Lin
  • Wenxiong Lin
  • Sheng Lin
  • Front Plant Sci.2020;11:601. doi: 10.3389/fpls.2020.00601.Epub 2020-05-28.

長い遺伝子間非プロテインコードRNA 01446は、ヒストンリジン特異的デメチラーゼLSD1と相互作用することにより、胃癌細胞の増殖と転移を促進する

Long intergenic non-protein-coding RNA 01446 facilitates the proliferation and metastasis of gastric cancer cells through interacting with the histone lysine-specific demethylase LSD1.
  • Yifan Lian
  • Changsheng Yan
  • Yikai Lian
  • Renzhi Yang
  • Qiongyun Chen
  • Dan Ma
  • Weibin Lian
  • Jingjing Liu
  • Chengyan Luo
  • Jianlin Ren
  • Hongzhi Xu
  • Cell Death Dis.2020 Jul;11(7):522. 10.1038/s41419-020-2729-0. doi: 10.1038/s41419-020-2729-0.Epub 2020-07-10.

急性先端膿瘍の疼痛コントロールにおけるコデイン系アセトアミノフェンの単離と関連性の比較：無作為化臨床試験

Comparison between isolated and associated with codeine acetaminophen in pain control of acute apical abscess: a randomized clinical trial.
  • Paula Barcellos da Silva
  • Aline Teixeira Mendes
  • Maria Beatriz Ferreira Cardoso
  • Ricardo Abreu da Rosa
  • Angela Longo do Nascimento
  • Jefferson Ricardo Pereira
  • Marcus Vinícius Reis Só
  • Clin Oral Investig.2020 Jul;10.1007/s00784-020-03374-6. doi: 10.1007/s00784-020-03374-6.Epub 2020-07-10.

共通の遺伝的感受性遺伝子座がPFAPA症候群、ベーチェット病、再発性無声性口内炎と関連しています

Common genetic susceptibility loci link PFAPA syndrome, Behçet's disease, and recurrent aphthous stomatitis.
  • Kalpana Manthiram
  • Silvia Preite
  • Fatma Dedeoglu
  • Selcan Demir
  • Seza Ozen
  • Kathryn M Edwards
  • Sivia Lapidus
  • Alexander E Katz
  • Henry M Feder
  • Maranda Lawton
  • Greg R Licameli
  • Peter F Wright
  • Julie Le
  • Karyl S Barron
  • Amanda K Ombrello
  • Beverly Barham
  • Tina Romeo
  • Anne Jones
  • Hemalatha Srinivasalu
  • Pamela A Mudd
  • Roberta L DeBiasi
  • Ahmet Gül
  • Gary S Marshall
  • Olcay Y Jones
  • Settara C Chandrasekharappa
  • Yuriy Stepanovskiy
  • Polly J Ferguson
  • Pamela L Schwartzberg
  • Elaine F Remmers
  • Daniel L Kastner
  • Proc. Natl. Acad. Sci. U.S.A..2020 Jun;117(25):14405-14411. 2002051117. doi: 10.1073/pnas.2002051117.Epub 2020-06-09.

血小板第4因子4は、Akt-PGC1α-TFAMシグナル伝達によるミトコンドリアの生合成を介してCD4 Tエフェクターメモリー細胞の応答を増強する

Platelet factor 4 enhances CD4 T effector memory cell responses via Akt-PGC1α-TFAM signaling-mediated mitochondrial biogenesis.
  • Shuai Tan
  • Shuijie Li
  • Yanan Min
  • Anton Gisterå
  • Noah Moruzzi
  • Junhao Zhang
  • Yang Sun
  • John Andersson
  • Rickard E Malmström
  • Miao Wang
  • Per-Olof Berggren
  • Susanne Schlisio
  • Wangjun Liao
  • Daniel F J Ketelhuth
  • Chunhong Ma
  • Nailin Li
  • J. Thromb. Haemost..2020 Jul;doi: 10.1111/jth.15005.Epub 2020-07-16.

経膣超音波検査卵子回収（TUGOR）のための麻酔薬としてのレミフェンタニルとプロポフォールの併用または非併用による妊娠と麻酔成績への影響。無作為化対照試験

Remifentanil with or without Propofol as Anesthesia Agents for Trans-Vaginal Ultrasonography Oocyte Retrieval (TUGOR) on Pregnancy and Anesthesia Outcomes: A Randomized Controlled Trial.
  • Simin Atashkhoei
  • Khadijeh Pouya
  • Parvin Hakimi
  • Raana Zakeri
  • Nasrin Soltanzadeh
  • Pouya Hatami-Marandi
  • Curr Clin Pharmacol.2020 Jun;CCP-EPUB-107593. doi: 10.2174/1574884715666200623161856.Epub 2020-06-23.

重症先天性心疾患を有する未熟児における先天性心臓手術のリスク調整区分と死亡率を新たに修正した

New modified version of the Risk Adjustment for Congenital Heart Surgery category and mortality in premature infants with critical congenital heart disease.
  • Young Mi Yoon
  • Seong Phil Bae
  • Yoon-Joo Kim
  • Jae Gun Kwak
  • Woong-Han Kim
  • Mi Kyoung Song
  • Seung Han Shin
  • Ee-Kyung Kim
  • Han-Suk Kim
  • Clin Exp Pediatr.2020 Jul;cep.2019.01522. doi: 10.3345/cep.2019.01522.Epub 2020-07-15.

S1PR4アブレーションは、CD8+ T細胞の増殖を介して腫瘍の増殖を抑制し、化学療法を改善する

S1PR4 ablation reduces tumor growth and improves chemotherapy via CD8+ T cell expansion.
  • Catherine Olesch
  • Evelyn Sirait-Fischer
  • Matthias Berkefeld
  • Annika F Fink
  • Rosa Martha Susen
  • Birgit Ritter
  • Birgitta E Michels
  • Dieter Steinhilber
  • Florian R Greten
  • Rajkumar Savai
  • Kazuhiko Takeda
  • Bernhard Brüne
  • Andreas Weigert
  • J. Clin. Invest..2020 Jul;136928. doi: 10.1172/JCI136928.Epub 2020-07-14.

アマゾン川流域（ペルー）に生息する6ツ葉のアマゾンウミガメPodocnemis sextuberculata（Pleurodira: Podocnemididae）に感染するカメブラッドフリューク（Platyhelminthes: Digenea: Schistosomatoidea）の新属と種について報告する

New Genus and Species of Turtle Blood Fluke (Platyhelminthes: Digenea: Schistosomatoidea) Infecting Six-Tubercled Amazon River Turtles, Podocnemis sextuberculata (Pleurodira: Podocnemididae) from the Amazon River Basin (Peru).
  • Haley R Dutton
  • Micah B Warren
  • Stephen A Bullard
  • J. Parasitol..2019 Oct;105(5):671-685. 420607. doi: 10.1645/19-68.

中国でのCOVID-19初発時の強制検疫の負の認知的・心理的相関

Negative cognitive and psychological correlates of mandatory quarantine during the initial COVID-19 outbreak in China.
  • Meiqi Xin
  • Sitong Luo
  • Rui She
  • Yanqiu Yu
  • Lijuan Li
  • Suhua Wang
  • Le Ma
  • Fangbiao Tao
  • Jianxin Zhang
  • Junfeng Zhao
  • Liping Li
  • Dongsheng Hu
  • Guohua Zhang
  • Jing Gu
  • Danhua Lin
  • Hongmei Wang
  • Yong Cai
  • Zhaofen Wang
  • Hua You
  • Guoqing Hu
  • Joseph Tak-Fai Lau
  • Am Psychol.2020 Jul-Aug;75(5):607-617. 2020-51214-002. doi: 10.1037/amp0000692.

デュルバルマブ、オラパリブ、パクリタキセルによる治療後のDSAP病変の苔癬状炎症。PDL-1阻害薬に関連した苔癬状の薬疹を模倣した診断上の落とし穴の可能性

Lichenoid inflammation of DSAP lesions following treatment with durvalumab, olaparib and paclitaxel: A potential diagnostic pitfall mimicking lichenoid drug eruptions associated with PDL-1 inhibitors.
  • Anastasia Shakhbazova
  • Brian Hinds
  • Amanda F Marsch
  • Dermatol. Online J..2020 Mar;26(3). 13030/qt7nf6c8hc. Epub 2020-03-15.

歯周病の有無にかかわらず子癇前症の妊婦の歯肉下および胎盤サンプルにおける微生物叢（ウイルスおよび細菌）の評価。横断的研究

Evaluation of Microflora (Viral and Bacterial) in Subgingival and Placental Samples of Pregnant Women with Preeclampsia with and without Periodontal Disease: A Cross-Sectional Study.
  • Swetha Tanneeru
  • Jaideep Mahendra
  • Mahaboob Vali Shaik
  • J Int Soc Prev Community Dent.2020 Mar-Apr;10(2):171-176. JISPCD-10-171. doi: 10.4103/jispcd.JISPCD_341_19.Epub 2020-03-10.

"リンゴは木から遠くに落ちていない" - 家族性高コレステロール血症を持つ子供の不顕性アテローム性動脈硬化症

"Apple does not fall far from the tree" - subclinical atherosclerosis in children with familial hypercholesterolemia.
  • Michał Podgórski
  • Katarzyna Szatko
  • Małgorzata Stańczyk
  • Monika Pawlak-Bratkowska
  • Agnieszka Konopka
  • Ewa Starostecka
  • Marcin Tkaczyk
  • Sebastian Góreczny
  • Lena Rutkowska
  • Agnieszka Gach
  • Maciej Łukaszewski
  • Piotr Grzelak
  • Maciej Banach
  • Lipids Health Dis.2020 Jul;19(1):169. 10.1186/s12944-020-01335-2. doi: 10.1186/s12944-020-01335-2.Epub 2020-07-14.

カメルーン中央部のヨーコの自然感染家畜におけるトリパノソーマ・コンゴレンセのジミナゼン酢酸耐性株の分子同定

Molecular identification of diminazene aceturate-resistant strains of Trypanosoma congolense in naturally infected domestic animals of Yoko in the centre region of Cameroon.
  • Estelle Mezajou Mewamba
  • Oumarou Farikou
  • Rolin Mitterran Ndefo Kamga
  • Melaine Eugenie Kemta Magang
  • Christopher Tume
  • Arnol Auvaker Zébazé Tiofack
  • Sophie Ravel
  • Gustave Simo
  • Vet Parasitol Reg Stud Reports.2020 Apr;20:100405. S2405-9390(19)30253-9. doi: 10.1016/j.vprsr.2020.100405.Epub 2020-03-28.

多発性硬化症患者の大集団におけるNabiximolsの中止率：18ヶ月の多施設共同研究

Nabiximols discontinuation rate in a large population of patients with multiple sclerosis: a 18-month multicentre study.
  • Clara Grazia Chisari
  • Claudio Solaro
  • Pasquale Annunziata
  • Roberto Bergamaschi
  • Assunta Bianco
  • Simona Bonavita
  • Vincenzo Brescia Morra
  • Roberto Bruno Bossio
  • Elisabetta Capello
  • Letizia Castelli
  • Paola Cavalla
  • Gianfranco Costantino
  • Diego Centonze
  • Salvatore Cottone
  • Maura Chiara Danni
  • Federica Esposito
  • Alberto Gajofatto
  • Claudio Gasperini
  • Angelica Guareschi
  • Roberta Lanzillo
  • Giacomo Lus
  • Giorgia Teresa Maniscalco
  • Manuela Matta
  • Damiano Paolicelli
  • Loredana Petrucci
  • Simona Pontecorvo
  • Isabella Righini
  • Marco Rovaris
  • Edoardo Sessa
  • Gabriella Spinicci
  • Daniele Spitaleri
  • Paola Valentino
  • Mauro Zaffaroni
  • Mario Zappia
  • Francesco Patti
  • J. Neurol. Neurosurg. Psychiatry.2020 Jul;jnnp-2019-322480. doi: 10.1136/jnnp-2019-322480.Epub 2020-07-13.

ステント支援コイル塞栓術時のNeuroform Atlasステントを用いた最適なステント可視化のためのヨード造影剤注入の最適濃度。実験に基づく症例検討

Optimum concentration of iodine contrast agent injection for best stent visualization using Neuroform Atlas stent during stent-assisted coil embolization: Case reviews based on experiments.
  • Shuta Aketa
  • Daisuke Wajima
  • Masayoshi Kiyomoto
  • Natsuhiko Izumi
  • Taiji Yonezawa
  • Surg Neurol Int.2020;11:170. SNI-11-170. doi: 10.25259/SNI_239_2020.Epub 2020-06-27.

淡水湖における植物プランクトン群集の豊富さ、バイオマス形成、構造に対するアレロパシー性ピコシアノバクテリウムsp.の重要性

The Importance of Allelopathic Picocyanobacterium sp. on the Abundance, Biomass Formation, and Structure of Phytoplankton Assemblages in Three Freshwater Lakes.
  • Iwona Bubak
  • Sylwia Śliwińska-Wilczewska
  • Paulina Głowacka
  • Agnieszka Szczerba
  • Katarzyna Możdżeń
  • Toxins (Basel).2020 Apr;12(4). E259. doi: 10.3390/toxins12040259.Epub 2020-04-16.

カンパラ、ウガンダのホスピタリティ会場での100％禁煙法に関連した知識、意見、コンプライアンス: カンパラからの横断的な結果

Knowledge, opinions and compliance related to the 100% smoke-free law in hospitality venues in Kampala, Uganda: cross-sectional results from the .
  • Shannon Gravely
  • Kellen Namusisi Nyamurungi
  • Steven Ndugwa Kabwama
  • Gabriel Okello
  • Lindsay Robertson
  • Kelvin Khow Chuan Heng
  • Achiri Elvis Ndikum
  • Adeniyi Samuel Oginni
  • Jean Christophe Rusatira
  • Socrates Kakoulides
  • Mark D Huffman
  • Salim Yusuf
  • Eduardo Bianco
  • BMJ Open.2018 01;8(1):e017601. bmjopen-2017-017601. doi: 10.1136/bmjopen-2017-017601.Epub 2018-01-05.

慢性閉塞性肺疾患の代謝シグネチャーのクロスオミクス統合的研究

A cross-omics integrative study of metabolic signatures of chronic obstructive pulmonary disease.
  • Ivana Prokić
  • Lies Lahousse
  • Maaike de Vries
  • Jun Liu
  • Marita Kalaoja
  • Judith M Vonk
  • Diana A van der Plaat
  • Cleo C van Diemen
  • Ashley van der Spek
  • Alexandra Zhernakova
  • Jingyuan Fu
  • Mohsen Ghanbari
  • Mika Ala-Korpela
  • Johannes Kettunen
  • Aki S Havulinna
  • Markus Perola
  • Veikko Salomaa
  • Lars Lind
  • Johan Ärnlöv
  • Bruno H C Stricker
  • Guy G Brusselle
  • H Marike Boezen
  • Cornelia M van Duijn
  • Najaf Amin
  • BMC Pulm Med.2020 Jul;20(1):193. 10.1186/s12890-020-01222-7. doi: 10.1186/s12890-020-01222-7.Epub 2020-07-16.

新しいSARS-CoV-2特異的抗体および中和アッセイは、COVID-19期の幅広い体液性免疫応答を明らかにした

Novel SARS-CoV-2 specific antibody and neutralization assays reveal wide range of humoral immune response during COVID-19.
  • Mikail Dogan
  • Lina Kozhaya
  • Lindsey Placek
  • Courtney Gunter
  • Mesut Yigit
  • Rachel Hardy
  • Matt Plassmeyer
  • Paige Coatney
  • Kimberleigh Lillard
  • Zaheer Bukhari
  • Michael Kleinberg
  • Chelsea Hayes
  • Moshe Arditi
  • Ellen Klapper
  • Noah Merin
  • Bruce T Liang
  • Raavi Gupta
  • Oral Alpan
  • Derya Unutmaz
  • medRxiv.2020 Jul;2020.07.07.20148106. doi: 10.1101/2020.07.07.20148106.Epub 2020-07-08.

免疫グロブリンM（IgM）多発性骨髄腫対Waldenströmマクログロブリン血症：診断上の課題と治療法の選択肢：2つの症例報告

Immunoglobulin M (IgM) multiple myeloma versus Waldenström macroglobulinemia: diagnostic challenges and therapeutic options: two case reports.
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