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日本語AIでPubMedを検索

歯科医師情報サイトTOP / PubMed論文検索

日本語AIでPubMedを検索

PubMedの提供する医学論文データベースを日本語で検索できます。AI(Deep Learning)を活用した機械翻訳エンジンにより、精度高く日本語へ翻訳された論文をご参照いただけます。
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2020年07月 みんなが読んでいる論文

ディープラーニングシステムがバレット食道患者の新生物を内視鏡医よりも高い精度で検出する多段階トレーニングとベンチマークを用いた検証研究

Deep-Learning System Detects Neoplasia in Patients With Barrett's Esophagus With Higher Accuracy Than Endoscopists in a Multistep Training and Validation Study With Benchmarking.
  • Albert J de Groof
  • Maarten R Struyvenberg
  • Joost van der Putten
  • Fons van der Sommen
  • Kiki N Fockens
  • Wouter L Curvers
  • Sveta Zinger
  • Roos E Pouw
  • Emmanuel Coron
  • Francisco Baldaque-Silva
  • Oliver Pech
  • Bas Weusten
  • Alexander Meining
  • Horst Neuhaus
  • Raf Bisschops
  • John Dent
  • Erik J Schoon
  • Peter H de With
  • Jacques J Bergman
  • Gastroenterology.2020 03;158(4):915-929.e4. S0016-5085(19)41586-2. doi: 10.1053/j.gastro.2019.11.030.Epub 2019-11-22.

小児肥満の減量のための専門家による行動介入を対人主導。系統的レビューとメタアナリシス

Layperson-Led vs Professional-Led Behavioral Interventions for Weight Loss in Pediatric Obesity: A Systematic Review and Meta-analysis.
  • Jonathan McGavock
  • Bhupendrasinh F Chauhan
  • Rasheda Rabbani
  • Sofia Dias
  • Nika Klaprat
  • Sara Boissoneault
  • Justin Lys
  • Aleksandra K Wierzbowski
  • Mohammad Nazmus Sakib
  • Ryan Zarychanski
  • Ahmed M Abou-Setta
  • JAMA Netw Open.2020 Jul;3(7):e2010364. 2768235. doi: 10.1001/jamanetworkopen.2020.10364.Epub 2020-07-01.

マダニ媒介フラビウイルスが毒蜘蛛の正体であるスフィンゴミエリン酵素（SMase）を阻害してスフィンゴミエリン脂質レベルを上昇させ、マダニの生存に寄与していることを明らかにした

Tick-Borne Flavivirus Inhibits Sphingomyelinase (SMase), a Venomous Spider Ortholog to Increase Sphingomyelin Lipid Levels for Its Survival in Ticks.
  • Pravesh Regmi
  • Supreet Khanal
  • Girish Neelakanta
  • Hameeda Sultana
  • Front Cell Infect Microbiol.2020;10:244. doi: 10.3389/fcimb.2020.00244.Epub 2020-06-12.

フェザーエッジまたは面取りをした歯肉下歯肉前処理をした前オールセラミッククラウン周辺の歯周安定性の二重センター横断的解析

Dual-Center Cross-Sectional Analysis of Periodontal Stability Around Anterior All-Ceramic Crowns with a Feather-Edge or Chamfer Subgingival Preparation.
  • Gianluca Paniz
  • Maciej Zarow
  • Jose Nart
  • Marta Peña
  • Gabriele Coltro
  • Christiano Tomasi
  • Eriberto Bressan
  • Int J Periodontics Restorative Dent.2020 Jukt/Aug;40(4):499-507. doi: 10.11607/prd.4500.

一般的に絶滅の危機に瀕しているカラデニア（ラン科）の同種の真菌類が関与する特定の菌根群集：保全への意味合い

Specific mycorrhizal associations involving the same fungal taxa in common and threatened Caladenia (Orchidaceae): implications for conservation.
  • Noushka Reiter
  • Ryan D Phillips
  • Nigel D Swarts
  • Magali Wright
  • Gareth Holmes
  • Frances C Sussmilch
  • Belinda J Davis
  • Michael R Whitehead
  • Celeste C Linde
  • Ann. Bot..2020 Jun;mcaa116. doi: 10.1093/aob/mcaa116.Epub 2020-06-24.

メデトミジンの筋肉内投与によるイヌの腹部血管系およびエンハンスメントダイナミックコンピュータ断層撮影法を用いた肝実質イメージングに対する鎮静効果

Effects of Sedation by Intramuscular Administration of Medetomidine on Canine Abdominal Vascular System and Hepatic Parenchyma Imaging Using Enhancement Dynamic Computed Tomography.
  • Kenji Kutara
  • Teppei Kanda
  • Noritaka Maeta
  • Yohei Mochizuki
  • Yoshiki Itoh
  • Fumiko Ono
  • Taketoshi Asanuma
  • Vet Sci.2020 Jul;7(3). E91. doi: 10.3390/vetsci7030091.Epub 2020-07-13.

メチシリン耐性黄色ブドウ球菌に感染した患者におけるパントンバレンチンロイコシジン遺伝子の有病率と敗血症リスクとの関連

Prevalence and association of Panton-Valentine Leukocidin gene with the risk of sepsis in patients infected with Methicillin Resistant Staphylococcus aureus.
  • Noor Ilham Ahmad
  • Chan Yean Yean
  • Phiaw Chong Foo
  • Amira Wahida Mohamad Safiee
  • Siti Asma' Hassan
  • J Infect Public Health.2020 Jul;S1876-0341(20)30528-1. doi: 10.1016/j.jiph.2020.06.018.Epub 2020-07-08.

遺伝子組換え大豆MON87751×MON87701×MON87708×MON89788の食品および飼料用途への評価、規則(EC) No 1829/2003(出願EFSA-GMO-NL-2016-128)に基づく

Assessment of genetically modified soybean MON 87751 × MON 87701 × MON 87708 × MON 89788 for food and feed uses, under Regulation (EC) No 1829/2003 (application EFSA-GMO-NL-2016-128).
  • Hanspeter Naegeli
  • Jean-Louis Bresson
  • Tamas Dalmay
  • Ian Crawford Dewhurst
  • Michelle M Epstein
  • Leslie George Firbank
  • Philippe Guerche
  • Jan Hejatko
  • Francisco Javier Moreno
  • Ewen Mullins
  • Fabien Nogué
  • Nils Rostoks
  • Jose Juan Sánchez Serrano
  • Giovanni Savoini
  • Eve Veromann
  • Fabio Veronesi
  • Fernando Álvarez
  • Michele Ardizzone
  • Giacomo De Sanctis
  • Yann Devos
  • Antonio Fernandez Dumont
  • Andrea Gennaro
  • Jose Ángel Gómez Ruiz
  • Anna Lanzoni
  • Franco Maria Neri
  • Nikoletta Papadopoulou
  • Konstantinos Paraskevopoulos
  • Tommaso Raffaello
  • EFSA J.2019 Nov;17(11):e05847. EFS25847. doi: 10.2903/j.efsa.2019.5847.Epub 2019-11-11.

酸素とグルコース欠乏にさらされた海馬スライスにおけるグアノシン神経保護作用は、ATPレベル、乳酸放出とグルタミン酸の取り込み障害を回復します。一酸化窒素の関与

Guanosine Neuroprotective Action in Hippocampal Slices Subjected to Oxygen and Glucose Deprivation Restores ATP Levels, Lactate Release and Glutamate Uptake Impairment: Involvement of Nitric Oxide.
  • Daniel Tonial Thomaz
  • Rafaela Rafognatto Andreguetti
  • Luisa Bandeira Binder
  • Débora da Luz Scheffer
  • Alisson Willms Corrêa
  • Fátima Regina Mena Barreto Silva
  • Carla Inês Tasca
  • Neurochem. Res..2020 Jul;10.1007/s11064-020-03083-2. doi: 10.1007/s11064-020-03083-2.Epub 2020-07-14.

赤道ギニア・ビオコ島の分離株中のスルファドキシン-ピリメタミン（SP）に対する耐性に関連する分子マーカーの傾向：2011-2017

Trends in Molecular Markers Associated with Resistance to Sulfadoxine-Pyrimethamine (SP) Among Isolates on Bioko Island, Equatorial Guinea: 2011-2017.
  • Li-Yun Lin
  • Jian Li
  • Hui-Ying Huang
  • Xue-Yan Liang
  • Ting-Ting Jiang
  • Jiang-Tao Chen
  • Carlos Salas Ehapo
  • Urbano Monsuy Eyi
  • Yu-Zhong Zheng
  • Guang-Cai Zha
  • Dong-De Xie
  • Yu-Ling Wang
  • Wei-Zhong Chen
  • Xiang-Zhi Liu
  • Min Lin
  • Infect Drug Resist.2020;13:1203-1212. 236898. doi: 10.2147/IDR.S236898.Epub 2020-04-28.

ブラジルの半乾燥地域の熱帯林（Caatinga）の季節的に乾燥した2つの対照的な地域における地表面放射量とエネルギーバランスの季節的変動

Seasonal variation of surface radiation and energy balances over two contrasting areas of the seasonally dry tropical forest (Caatinga) in the Brazilian semi-arid.
  • Camilla K Borges
  • Carlos A C Dos Santos
  • Rayonil G Carneiro
  • Lindenberg L da Silva
  • Gabriel de Oliveira
  • Denis Mariano
  • Madson T Silva
  • Bernardo B da Silva
  • Bergson G Bezerra
  • Aldrin M Perez-Marin
  • Salomão de S Medeiros
  • Environ Monit Assess.2020 Jul;192(8):524. 10.1007/s10661-020-08484-y. doi: 10.1007/s10661-020-08484-y.Epub 2020-07-16.

血栓溶解療法後の女性の予後は男性に比べて悪い。アジアの急性期脳卒中登録を対象とした個別患者データプール研究

Worse prognosis in women, compared with men, after thrombolysis: An individual patient data pooling study of Asian acute stroke registries.
  • Xia Wang
  • Cheryl Carcel
  • Ruigang Wang
  • Jingwei Li
  • Hee-Joon Bae
  • Yilong Wang
  • Anxin Wang
  • Yongjun Wang
  • Kazunori Toyoda
  • Yi Sui
  • Tsong-Hai Lee
  • Jose C Navarro
  • Mu-Chien Sun
  • Craig S Anderson
  • Vijay Sharma
  • Else C Sandset
  • Mark Woodward
  • Int J Stroke.2020 Jul;:1747493020938307. doi: 10.1177/1747493020938307.Epub 2020-07-08.

バレット食道における早期新生物の分類のための深層主成分符号化法と体積レーザー内視鏡検査

Deep principal dimension encoding for the classification of early neoplasia in Barrett's Esophagus with volumetric laser endomicroscopy.
  • Joost van der Putten
  • Maarten Struyvenberg
  • Jeroen de Groof
  • Thom Scheeve
  • Wouter Curvers
  • Erik Schoon
  • Jacques J G H M Bergman
  • Peter H N de With
  • Fons van der Sommen
  • Comput Med Imaging Graph.2020 Mar;80:101701. S0895-6111(20)30004-5. doi: 10.1016/j.compmedimag.2020.101701.Epub 2020-01-24.

プライマリケアの医師とセカンダリケアの医師では、クロスレベルの臨床調整の経験と認識が異なるのか？カタルーニャ州の国民医療システム（スペイン）における横断的研究の結果

Do primary and secondary care doctors have a different experience and perception of cross-level clinical coordination? Results of a cross-sectional study in the Catalan National Health System (Spain).
  • Laura Esteve-Matalí
  • Ingrid Vargas
  • Elvira Sánchez
  • Isabel Ramon
  • Pere Plaja
  • María-Luisa Vázquez
  • BMC Fam Pract.2020 Jul;21(1):135. 10.1186/s12875-020-01207-9. doi: 10.1186/s12875-020-01207-9.Epub 2020-07-08.

インターフェロンγ-およびリポ多糖刺激馬の末梢血単核細胞による腫瘍壊死因子αの産生に対するポリ（ADP-リボース）ポリメラーゼ阻害剤のin vitro効果

In vitro effects of poly(ADP-ribose) polymerase inhibitors on the production of tumor necrosis factor-α by interferon- γ - and lipopolysaccharide-stimulated peripheral blood mononuclear cells of horses.
  • Cristina Cacciolatti
  • Mirella L Meyer-Ficca
  • Louise L Southwood
  • Ralph G Meyer
  • Luigi Bertolotti
  • Laura Zarucco
  • Am. J. Vet. Res..2019 Jul;80(7):663-669. doi: 10.2460/ajvr.80.7.663.

セリンヒドロキシメチルトランスフェラーゼの変異は、大豆の可溶性 NSF 付着タンパク質および発病関連タンパク質との相互作用に影響を与える

Mutations at the Serine Hydroxymethyltransferase Impact its Interaction with a Soluble NSF Attachment Protein and a Pathogenesis-Related Protein in Soybean.
  • Naoufal Lakhssassi
  • Sarbottam Piya
  • Dounya Knizia
  • Abdelhalim El Baze
  • Mallory A Cullen
  • Jonas Meksem
  • Aicha Lakhssassi
  • Tarek Hewezi
  • Khalid Meksem
  • Vaccines (Basel).2020 Jun;8(3). E349. doi: 10.3390/vaccines8030349.Epub 2020-06-30.

デクスメデトミジンはオートファジーα2-AR/AMPK/mTOR経路を強化し、NLRP3インフラマソームの活性化を抑制し、リポ多糖類誘発性急性腎障害を軽減します

Dexmedetomidine Enhances Autophagy α2-AR/AMPK/mTOR Pathway to Inhibit the Activation of NLRP3 Inflammasome and Subsequently Alleviates Lipopolysaccharide-Induced Acute Kidney Injury.
  • Tianyuan Yang
  • Xiujing Feng
  • Yuan Zhao
  • Haiyang Zhang
  • Hailin Cui
  • Mian Wei
  • Haotian Yang
  • Honggang Fan
  • Front Pharmacol.2020;11:790. doi: 10.3389/fphar.2020.00790.Epub 2020-06-24.

性は肝性脳症における腸内微生物組成・機能の違いと関連している

Sex is associated with differences in gut microbial composition and function in hepatic encephalopathy.
  • Krishnakant Saboo
  • Amirhossein Shamsaddini
  • Mihir V Iyer
  • Chang Hu
  • Andrew Fagan
  • Edith A Gavis
  • Melanie B White
  • Michael Fuchs
  • Douglas M Heuman
  • Masoumeh Sikaroodi
  • Ravishankar K Iyer
  • Patrick M Gillevet
  • Jasmohan S Bajaj
  • J. Hepatol..2020 Jul;S0168-8278(20)30457-8. doi: 10.1016/j.jhep.2020.06.046.Epub 2020-07-14.

著者訂正。アディポネクチンはT-カドヘリンと結合して筋肉の再生を促進する

Author Correction: Adiponectin promotes muscle regeneration through binding to T-cadherin.
  • Yoshimitsu Tanaka
  • Shunbun Kita
  • Hitoshi Nishizawa
  • Shiro Fukuda
  • Yuya Fujishima
  • Yoshinari Obata
  • Hirofumi Nagao
  • Shigeki Masuda
  • Yuto Nakamura
  • Yuri Shimizu
  • Ryohei Mineo
  • Tomoaki Natsukawa
  • Tohru Funahashi
  • Barbara Ranscht
  • So-Ichiro Fukada
  • Norikazu Maeda
  • Iichiro Shimomura
  • Sci Rep.2020 Jul;10(1):12219. 10.1038/s41598-020-66545-1. doi: 10.1038/s41598-020-66545-1.Epub 2020-07-17.

TGF-βはHDAC6を介して一次繊毛の短縮と歪みを介してヒト骨芽細胞の力学的感覚を損なう

TGF-β impairs mechanosensation of human osteoblasts via HDAC6-mediated shortening and distortion of primary cilia.
  • Sabrina Ehnert
  • Vrinda Sreekumar
  • Romina H Aspera-Werz
  • Sahar O Sajadian
  • Elke Wintermeyer
  • Gunther H Sandmann
  • Christian Bahrs
  • Jan G Hengstler
  • Patricio Godoy
  • Andreas K Nussler
  • J. Mol. Med..2017 06;95(6):653-663. 10.1007/s00109-017-1526-4. doi: 10.1007/s00109-017-1526-4.Epub 2017-03-07.

子宮内成長制限は、ヒト臍帯静脈における一酸化窒素/環状GMP緩和経路の性特異的変化と関連している

Intrauterine growth restriction is associated with sex-specific alterations in the nitric oxide/cyclic GMP relaxing pathway in the human umbilical vein.
  • Manon Beaumann
  • Flavien Delhaes
  • Steeve Menétrey
  • Sébastien Joye
  • Yvan Vial
  • David Baud
  • Jacquier Goetschmann Magaly
  • Jean-François Tolsa
  • Anne-Christine Peyter
  • Placenta.2020 04;93:83-93. S0143-4004(20)30062-X. doi: 10.1016/j.placenta.2020.02.014.Epub 2020-02-25.

肥培地および無肥培地で培養したススキのファイトレメディエーションポテンシャルと生理応答（英文

Phytoremediation potential and physiological response of Miscanthus × giganteus cultivated on fertilized and non-fertilized flotation tailings.
  • Gordana Andrejić
  • Jasmina Šinžar-Sekulić
  • Milijana Prica
  • Željko Dželetović
  • Tamara Rakić
  • Environ Sci Pollut Res Int.2019 Nov;26(33):34658-34669. 10.1007/s11356-019-06543-7. doi: 10.1007/s11356-019-06543-7.Epub 2019-10-25.

非狭窄性急性小腸閉塞に対するガストロフィン腸管挿管または長管挿管を用いた経鼻胃管挿管による初回管理：多施設無作為化比較試験

The first management using intubation of a nasogastric tube with Gastrografin enterography or long tube for non-strangulated acute small bowel obstruction: a multicenter, randomized controlled trial.
  • Takahito Katano
  • Takaya Shimura
  • Hirotada Nishie
  • Tomohiro Iwai
  • Keisuke Itoh
  • Masahide Ebi
  • Yusuke Mizuno
  • Shozo Togawa
  • Shunsuke Shibata
  • Tomonori Yamada
  • Takashi Mizushima
  • Yusuke Inagaki
  • Mika Kitagawa
  • Yu Nojiri
  • Yoshito Tanaka
  • Yasuyuki Okamoto
  • Miyuki Sugiura
  • Sho Matoya
  • Yoshihito Nagura
  • Yuki Inagaki
  • Hiroki Koguchi
  • Satoshi Ono
  • Keiji Ozeki
  • Noriyuki Hayashi
  • Shuji Takiguchi
  • Hiromi Kataoka
  • J. Gastroenterol..2020 Jul;10.1007/s00535-020-01708-5. doi: 10.1007/s00535-020-01708-5.Epub 2020-07-15.

PKGとAktの活性化はラメルテオン誘発前処理による心保護に必要であり、mKCaチャネルの上流に位置している

Activation of PKG and Akt Is Required for Cardioprotection by Ramelteon-Induced Preconditioning and Is Located Upstream of mKCa-Channels.
  • Carolin Torregroza
  • Osameh Jalajel
  • Annika Raupach
  • Katharina Feige
  • Sebastian Bunte
  • André Heinen
  • Alexander Mathes
  • Markus W Hollmann
  • Ragnar Huhn
  • Martin Stroethoff
  • Int J Mol Sci.2020 Apr;21(7). E2585. doi: 10.3390/ijms21072585.Epub 2020-04-08.

マラリア撲滅に向けたカーボベルデ集団におけるグルコース-6-リン酸デヒドロゲナーゼ欠損症の有病率

The prevalence of glucose-6-phosphate dehydrogenase deficiency in the Cape Verdean population in the context of malaria elimination.
  • Adilson José DePina
  • Cecílio Mendes Pires
  • Alex Jailson Barbosa Andrade
  • Abdoulaye Kane Dia
  • António Lima Moreira
  • Maria Celina Moreira Ferreira
  • Artur Jorge Correia
  • Ousmane Faye
  • Ibrahima Seck
  • El Hadji Amadou Niang
  • PLoS ONE.2020;15(3):e0229574. PONE-D-19-10520. doi: 10.1371/journal.pone.0229574.Epub 2020-03-16.

テルミサルタンの高可動性グループボックス1およびグリコーゲン合成酵素キナーゼ-3β/核因子-κB経路の阻害を通じた敗血症誘発性心筋障害における有益な役割を探る

Exploring the beneficial role of telmisartan in sepsis-induced myocardial injury through inhibition of high-mobility group box 1 and glycogen synthase kinase-3β/nuclear factor-κB pathway.
  • Yan Jin
  • Hong Wang
  • Jing Li
  • Minyan Dang
  • Wenzhi Zhang
  • Yan Lei
  • Hao Zhao
  • Korean J. Physiol. Pharmacol..2020 Jul;24(4):311-317. kjpp.2020.24.4.311. doi: 10.4196/kjpp.2020.24.4.311.

フランスの医療保険データベースを使用して、潜在的な薬物-薬物相互作用への曝露の有病率を推定した

Use of the French healthcare insurance database to estimate the prevalence of exposure to potential drug-drug interactions.
  • Cécile Souty
  • Titouan Launay
  • Olivier Steichen
  • Cécile Conte
  • Clément Turbelin
  • Marianne Sarazin
  • Ana-Maria Vilcu
  • Louise Rossignol
  • Thierry Blanchon
  • Maryse Lapeyre-Mestre
  • Thomas Hanslik
  • Eur. J. Clin. Pharmacol..2020 Jul;10.1007/s00228-020-02952-7. doi: 10.1007/s00228-020-02952-7.Epub 2020-07-07.

エストロゲン欠乏症における骨芽細胞と骨細胞のミネラル化とプロステオブラストの副次的シグナル伝達の変化を明らかにする新しい3次元骨芽細胞・骨細胞モデルの開発

A Novel 3D Osteoblast and Osteocyte Model Revealing Changes in Mineralization and Pro-osteoclastogenic Paracrine Signaling During Estrogen Deficiency.
  • Syeda Masooma Naqvi
  • Juan Alberto Panadero Pérez
  • Vatsal Kumar
  • Anneke S K Verbruggen
  • Laoise M McNamara
  • Front Bioeng Biotechnol.2020;8:601. doi: 10.3389/fbioe.2020.00601.Epub 2020-06-10.

グローバルCndp1ノックアウトにより、マウスの腎内カルノシンおよびアンセリン濃度が年齢および性別に応じて選択的に増加することを明らかにした

A Global Cndp1-Knock-Out Selectively Increases Renal Carnosine and Anserine Concentrations in an Age- and Gender-Specific Manner in Mice.
  • Tim Weigand
  • Florian Colbatzky
  • Tilman Pfeffer
  • Sven F Garbade
  • Kristina Klingbeil
  • Florian Colbatzky
  • Michael Becker
  • Johanna Zemva
  • Ruben Bulkescher
  • Robin Schürfeld
  • Christian Thiel
  • Nadine Volk
  • David Reuss
  • Georg F Hoffmann
  • Marc Freichel
  • Markus Hecker
  • Tanja Poth
  • Thomas Fleming
  • Gernot Poschet
  • Claus P Schmitt
  • Verena Peters
  • Int J Mol Sci.2020 Jul;21(14). E4887. doi: 10.3390/ijms21144887.Epub 2020-07-10.

HIV陽性妊婦におけるラミブジン、ジドブジン、ロピナビル、リトナビル血漿中濃度の評価患者の安全性向上のための薬物モニタリングアプリケーション

Assessment of lamivudine, zidovudine, lopinavir, and ritonavir plasma levels in HIV-positive pregnant women: Drug monitoring application to improve patient safety.
  • Jessica Hernández-Pineda
  • Helgi Helene Jung-Cook
  • Norah Lucky Katende-Kyenda
  • Norma Galindo-Sevilla
  • Mauricio Domínguez-Castro
  • José Romo-Yañéz
  • Alicia Ramírez-Ramírez
  • Claudine Irles
  • Ricardo Figueroa-Damián
  • Medicine (Baltimore).2020 May;99(22):e20487. 00005792-202005290-00104. doi: 10.1097/MD.0000000000020487.

ウルグアイの牛から採取されたロタウイルスAの系統解析により、一般的な遺伝子型と非一般的な遺伝子型が循環していることが明らかになり、種間伝播が示唆された

Phylogenetic Analyses of Rotavirus A from Cattle in Uruguay Reveal the Circulation of Common and Uncommon Genotypes and Suggest Interspecies Transmission.
  • Matías Castells
  • Rubén Darío Caffarena
  • María Laura Casaux
  • Carlos Schild
  • Samuel Miño
  • Felipe Castells
  • Daniel Castells
  • Matías Victoria
  • Franklin Riet-Correa
  • Federico Giannitti
  • Viviana Parreño
  • Rodney Colina
  • Pathogens.2020 Jul;9(7). E570. doi: 10.3390/pathogens9070570.Epub 2020-07-14.

高地の畑地で栽培されたイネにおけるセレンの毒性。μ-XRF法を用いた種子生理応答と栄養分布の解析

Selenium toxicity in upland field-grown rice: Seed physiology responses and nutrient distribution using the μ-XRF technique.
  • André Rodrigues Dos Reis
  • Eduardo Henrique Marcandalli Boleta
  • Charline Zaratin Alves
  • Mayara Fávero Cotrim
  • Julierme Zimmer Barbosa
  • Vinícius Martins Silva
  • Rafael Lawandovski Porto
  • Maria Gabriela Dantas Bereta Lanza
  • José Lavres
  • Marcos Henrique Feresin Gomes
  • Hudson Wallace Pereira de Carvalho
  • Ecotoxicol. Environ. Saf..2020 Mar;190:110147. S0147-6513(19)31478-2. doi: 10.1016/j.ecoenv.2019.110147.Epub 2020-01-07.

BDE-209の経口曝露は、B16-F10細胞を接種したC57BL/6マウスにおけるメラノーマの転移性拡大を調節する

Oral exposure to BDE-209 modulates metastatic spread of melanoma in C57BL/6 mice inoculated with B16-F10 cells.
  • Patricia Manuitt Brito
  • Stellee Marcela Petris Biscaia
  • Tugstenio Lima de Souza
  • Amandia Batscheuer Ramos
  • Joelma Leão-Buchir
  • Aliciane de Almeida Roque
  • Daniel de Lima Bellan
  • Edvaldo da Silva Trindade
  • Francisco Filipak Neto
  • Ciro Alberto de Oliveira Ribeiro
  • Chemosphere.2020 Jul;260:127556. S0045-6535(20)31751-3. doi: 10.1016/j.chemosphere.2020.127556.Epub 2020-07-10.

口蓋上皮におけるトランスフォーミング成長因子ベータおよびソニックヘッジホッグシグナル伝達は、軟口蓋発生期の口蓋間葉におけるテナシン-Cの発現を制御する

Transforming Growth Factor-Beta and Sonic Hedgehog Signaling in Palatal Epithelium Regulate Tenascin-C Expression in Palatal Mesenchyme During Soft Palate Development.
  • Shirabe Ohki
  • Kyoko Oka
  • Kayoko Ogata
  • Shigeru Okuhara
  • Mihoko Rikitake
  • Masako Toda-Nakamura
  • Shougo Tamura
  • Masao Ozaki
  • Sachiko Iseki
  • Takayoshi Sakai
  • Front Physiol.2020;11:532. doi: 10.3389/fphys.2020.00532.Epub 2020-06-04.

精神病を有する双極性障害、統合失調症、統合感情障害を有する双極性障害、精神病を有しない双極性障害、統合失調症、統合感情障害を有する双極性障害の間で、抑制性コントロールと一般認知能力の障害のパターンを区別することができる

Distinguishing patterns of impairment on inhibitory control and general cognitive ability among bipolar with and without psychosis, schizophrenia, and schizoaffective disorder.
  • Milena Y Gotra
  • Scot K Hill
  • Elliot S Gershon
  • Carol A Tamminga
  • Elena I Ivleva
  • Godfrey D Pearlson
  • Matcheri S Keshavan
  • Brett A Clementz
  • Jennifer E McDowell
  • Peter F Buckley
  • John A Sweeney
  • Sarah K Keedy
  • Schizophr. Res..2020 Jul;S0920-9964(20)30385-6. doi: 10.1016/j.schres.2020.06.033.Epub 2020-07-13.

F2-アミノ-4-((2-((3-フルオロベンジル)オキシ)ベンジル)(2-((3-(フルオロメチル)ベンジル)オキシ)ベンジル)アミノ)ブタン酸の放射性合成、in vitroおよび予備的生物学的評価を行った

Radiosynthesis, in vitro and preliminary biological evaluation of [ F]2-amino-4-((2-((3-fluorobenzyl)oxy)benzyl)(2-((3-(fluoromethyl)benzyl)oxy)benzyl)amino)butanoic acid, a novel alanine serine cysteine transporter 2 inhibitor-based positron emission tomography tracer.
  • Tristan Baguet
  • Jakob Bouton
  • Jonas Janssens
  • Glenn Pauwelyn
  • Jeroen Verhoeven
  • Benedicte Descamps
  • Serge Van Calenbergh
  • Christian Vanhove
  • Filip De Vos
  • J Labelled Comp Radiopharm.2020 May;doi: 10.1002/jlcr.3863.Epub 2020-05-30.

EU域外種の害虫分類

Pest categorisation of non-EU spp.
  • Claude Bragard
  • Katharina Dehnen-Schmutz
  • Francesco Di Serio
  • Paolo Gonthier
  • Marie-Agnès Jacques
  • Josep Anton Jaques Miret
  • Annemarie Fejer Justesen
  • Alan MacLeod
  • Christer Sven Magnusson
  • Juan A Navas-Cortes
  • Stephen Parnell
  • Roel Potting
  • Philippe Lucien Reignault
  • Hans-Hermann Thulke
  • Wopke Van der Werf
  • Antonio Vicent Civera
  • Jonathan Yuen
  • Lucia Zappalà
  • Jean-Claude Grégoire
  • Virág Kertész
  • Panagiotis Milonas
  • EFSA J.2019 Oct;17(10):e05856. EFS25856. doi: 10.2903/j.efsa.2019.5856.Epub 2019-10-31.

2016年から2017年までのミシガン州メディケイド拡大登録者の健康状態の変化の検討

Examination of Changes in Health Status Among Michigan Medicaid Expansion Enrollees From 2016 to 2017.
  • Minal R Patel
  • Renuka Tipirneni
  • Edith C Kieffer
  • Jeffrey T Kullgren
  • John Z Ayanian
  • Tammy Chang
  • Erica Solway
  • Erin Beathard
  • Matthias Kirch
  • Sunghee Lee
  • Sarah Clark
  • Jennifer Skillicorn
  • Zachary Rowe
  • Susan D Goold
  • JAMA Netw Open.2020 Jul;3(7):e208776. 2768102. doi: 10.1001/jamanetworkopen.2020.8776.Epub 2020-07-01.

個々の宿主の胃食道粘膜におけるテトラサイクリンに対する感受性と耐性の低下に関連する分離株の16S単一変異のリアルタイムPCR検出

Real-time PCR detection of a 16S single mutation of isolates associated with reduced susceptibility and resistance to tetracycline in the gastroesophageal mucosa of individual hosts.
  • Monica Contreras
  • Lucie Benejat
  • Heisser Mujica
  • Jessy Peña
  • María-Alexandra García-Amado
  • Fabian Michelangeli
  • Philippe Lehours
  • J. Med. Microbiol..2019 Sep;68(9):1287-1291. doi: 10.1099/jmm.0.001051.

マイクロメートルサイズのナノポーラス粒子への整列セルロースナノ結晶のトップダウンアセンブリに利用される植物細胞壁のネイティブ構造

Native Structure of the Plant Cell Wall Utilized for Top-Down Assembly of Aligned Cellulose Nanocrystals into Micrometer-Sized Nanoporous Particles.
  • Panagiotis Spiliopoulos
  • Iina Solala
  • Timo Pääkkönen
  • Jani Seitsonen
  • Bas van Bochove
  • Jukka V Seppälä
  • Eero Kontturi
  • Macromol Rapid Commun.2020 Jul;:e2000201. doi: 10.1002/marc.202000201.Epub 2020-07-01.

炭酸脱水酵素阻害剤アセタゾラミドは、A20/BalbCマウスB細胞リンパ腫におけるCHOP治療応答を増強し、エフェクターT細胞浸潤を刺激する

Carbonic Anhydrase Inhibitor Acetazolamide Enhances CHOP Treatment Response and Stimulates Effector T-Cell Infiltration in A20/BalbC Murine B-Cell Lymphoma.
  • Gábor Méhes
  • Orsolya Matolay
  • Lívia Beke
  • Marianna Czenke
  • Róbert Pórszász
  • Edit Mikó
  • Péter Bai
  • Ervin Berényi
  • György Trencsényi
  • Int J Mol Sci.2020 Jul;21(14). E5001. doi: 10.3390/ijms21145001.Epub 2020-07-15.

エチル2-(2)-2-(2-クロロベンジルイデン)-3-オキソ-3,4-ジヒドロ-2,4-ベンゾ-チアジン-4-イルアセテートの結晶構造、ヒルシュフェルト表面分析および相互作用エネルギー、DFTおよび抗菌活性の研究

Crystal structure, Hirshfeld surface analysis and inter-action energy, DFT and anti-bacterial activity studies of ethyl 2-[(2)-2-(2-chloro-benzyl-idene)-3-oxo-3,4-di-hydro-2-1,4-benzo-thia-zin-4-yl]acetate.
  • Ghizlane Sebbar
  • Ellouz Mohamed
  • Tuncer Hökelek
  • Joel T Mague
  • Nada Kheira Sebbar
  • El Mokhtar Essassi
  • Bouchra Belkadi
  • Acta Crystallogr E Crystallogr Commun.2020 May;76(Pt 5):629-636. lh5950. doi: 10.1107/S2056989020004119.Epub 2020-04-07.

トリプルネガティブ乳癌の特異的標的化および局所治療のための標的治療薬としての LHRH 抱合薬

LHRH-Conjugated Drugs as Targeted Therapeutic Agents for the Specific Targeting and Localized Treatment of Triple Negative Breast Cancer.
  • J D Obayemi
  • A A Salifu
  • S C Eluu
  • V O Uzonwanne
  • S M Jusu
  • C C Nwazojie
  • C E Onyekanne
  • O Ojelabi
  • L Payne
  • C M Moore
  • J A King
  • W O Soboyejo
  • Sci Rep.2020 May;10(1):8212. 10.1038/s41598-020-64979-1. doi: 10.1038/s41598-020-64979-1.Epub 2020-05-19.

技術的留意事項：アトラスベースのセグメンテーションによるバルク密度の割り当てを用いた前立腺のMRIのみに基づく効率的かつ正確な治療計画

Technical note: Efficient and accurate MRI-only based treatment planning of the prostate using bulk density assignment through atlas-based segmentation.
  • Hazel Mhairi McCallum
  • Sebastian Andersson
  • Jonathan James Wyatt
  • Neil Richmond
  • Christopher Paul Walker
  • Stina Svensson
  • Med Phys.2020 Jul;doi: 10.1002/mp.14406.Epub 2020-07-18.

ショートコミュニケーション。伝統的および直接酸性化技術を用いて製造された高水分モッツァレラの官能特性と揮発性有機化合物プロファイル

Short communication: Sensory characteristics and volatile organic compound profile of high-moisture mozzarella made by traditional and direct acidification technology.
  • G Natrella
  • M Faccia
  • J M Lorenzo
  • P De Palo
  • G Gambacorta
  • J. Dairy Sci..2020 Mar;103(3):2089-2097. S0022-0302(20)30019-9. doi: 10.3168/jds.2019-17059.Epub 2020-01-15.

発達する髄膜の単細胞トランスクリプトーム解析により、髄膜線維芽細胞の多様性と機能が明らかになった

Single-Cell Transcriptomic Analyses of the Developing Meninges Reveal Meningeal Fibroblast Diversity and Function.
  • John DeSisto
  • Rebecca O'Rourke
  • Hannah E Jones
  • Bradley Pawlikowski
  • Alexandra D Malek
  • Stephanie Bonney
  • Fabien Guimiot
  • Kenneth L Jones
  • Julie A Siegenthaler
  • Dev. Cell.2020 Jul;54(1):43-59.e4. S1534-5807(20)30459-7. doi: 10.1016/j.devcel.2020.06.009.

重症化した頭蓋顔面多形性線維性異形成症の外科的管理における段階的凍結手術と三次元CT一体型ナビゲーションシステムの役割

The Role of Staged Cryosurgery and Three-Dimensional Computed Tomography Integrated Navigation System in the Surgical Management of Severe Involvement of Craniofacial Polyostotic Fibrous Dysplasia.
  • Kemalettin Yildiz
  • Tolga Turan Dündar
  • Anas Abdallah
  • Turan Mehdizade
  • Ethem Güneren
  • Halil Ibrahim Canter
  • J Craniofac Surg.2020 Jun;31(4):1006-1009. 00001665-202006000-00028. doi: 10.1097/SCS.0000000000006348.

1000 個のタンパク質の定量的な平面配列のスクリーニングにより、ループス腎炎の新規な尿中タンパク質バイオマーカーが明らかになった

Quantitative planar array screen of 1000 proteins uncovers novel urinary protein biomarkers of lupus nephritis.
  • Kamala Vanarsa
  • Sanam Soomro
  • Ting Zhang
  • Briony Strachan
  • Claudia Pedroza
  • Malavika Nidhi
  • Pietro Cicalese
  • Christopher Gidley
  • Shobha Dasari
  • Shree Mohan
  • Nathan Thai
  • Van Thi Thanh Truong
  • Nicole Jordan
  • Ramesh Saxena
  • Chaim Putterman
  • Michelle Petri
  • Chandra Mohan
  • Ann. Rheum. Dis..2020 Jul;annrheumdis-2019-216312. doi: 10.1136/annrheumdis-2019-216312.Epub 2020-07-10.

固体脂質微粒子（SLM）の液体分散液中の薬物-脂質相互作用と活性物質分布の評価のための分析技術

Analytical Techniques for the Assessment of Drug-Lipid Interactions and the Active Substance Distribution in Liquid Dispersions of Solid Lipid Microparticles (SLM) Produced de novo and Reconstituted from Spray-Dried Powders.
  • Eliza Wolska
  • Małgorzata Sznitowska
  • Katarzyna Krzemińska
  • Maria Ferreira Monteiro
  • Pharmaceutics.2020 Jul;12(7). E664. doi: 10.3390/pharmaceutics12070664.Epub 2020-07-15.

細胞壁損傷シグナル伝達ネットワークの拡張は、転写因子Rlm1とSko1によって構成されている

An expanded cell wall damage signaling network is comprised of the transcription factors Rlm1 and Sko1 in Candida albicans.
  • Marienela Y Heredia
  • Mélanie A C Ikeh
  • Deepika Gunasekaran
  • Karen A Conrad
  • Sviatlana Filimonava
  • Dawn H Marotta
  • Clarissa J Nobile
  • Jason M Rauceo
  • PLoS Genet..2020 Jul;16(7):e1008908. PGENETICS-D-20-00595. doi: 10.1371/journal.pgen.1008908.Epub 2020-07-08.

ヒトパピローマウイルス16型E7はEGFR/PI3K/AKT1/NRF2シグナル伝達経路を促進し、口腔癌細胞のPIR/NF-κB活性化に寄与している

Human Papillomavirus 16 E7 Promotes EGFR/PI3K/AKT1/NRF2 Signaling Pathway Contributing to PIR/NF-κB Activation in Oral Cancer Cells.
  • Diego Carrillo-Beltrán
  • Juan P Muñoz
  • Nahir Guerrero-Vásquez
  • Rancés Blanco
  • Oscar León
  • Vanesca de Souza Lino
  • Julio C Tapia
  • Edio Maldonado
  • Karen Dubois-Camacho
  • Marcela A Hermoso
  • Alejandro H Corvalán
  • Gloria M Calaf
  • Enrique Boccardo
  • Francisco Aguayo
  • Cancers (Basel).2020 Jul;12(7). E1904. doi: 10.3390/cancers12071904.Epub 2020-07-15.

新規に製造した減感作剤、クロルヘキシジンおよびグルマのコンポジットと象牙質との接着強度および接着寿命に対するin vitro比較評価

In Vitro Comparative Evaluation of Newly Produced Desensitizer, Chlorhexidine and Gluma on Bond Strength and Bond Longevity of Composite to Dentin.
  • Reza Davalloo
  • Seyedeh Maryam Tavangar
  • Heshmatollah Ebrahimi
  • Farideh Darabi
  • Shima Mahmoudi
  • J Dent (Shiraz).2020 Jun;21(2):111-118. JDS-21-2. doi: 10.30476/DENTJODS.2019.77756.0.

μ-カルパインの過剰な量と活性は、慢性B細胞性白血病細胞のアポトーシス機構に影響を与え、疾患の経過に影響を与えます

Excessive amount and activity of μ-calpain affects apoptotic machinery in chronic B-cell leukemia cells and influences the course of the disease.
  • Paulina Łopatniuk
  • Zofia Puchalska
  • Andrzej Mital
  • Anna Mikosik
  • Joanna Frąckowiak
  • Andrzej Hellmann
  • Agnieszka Daca
  • Ewa Bryl
  • Tamas Fulop
  • Jacek M Witkowski
  • Acta Biochim. Pol..2020 Jun;67(2):247-257. 5226. doi: 10.18388/abp.2020_5226.

NF-κB シグナル伝達経路の強力な阻害剤であるバイカリンは、乳がん細胞のドセタキセルに対する化学感受性を高め、 腫瘍の増殖と転移の両方を抑制することを明らかにした

Baicalin, a Potent Inhibitor of NF-κB Signaling Pathway, Enhances Chemosensitivity of Breast Cancer Cells to Docetaxel and Inhibits Tumor Growth and Metastasis Both and .
  • Anqi Zeng
  • Xin Liang
  • Shaomi Zhu
  • Chi Liu
  • Xiaohong Luo
  • Qinxiu Zhang
  • Linjiang Song
  • Front Pharmacol.2020;11:879. doi: 10.3389/fphar.2020.00879.Epub 2020-06-17.

カダベリック模擬腫瘍モデルでナビゲーション支援下の筋骨格系腫瘍切除術を計画する場合、皮膚フィデューシャルは骨フィデューシャルと比較して登録が可能か？

Are Skin Fiducials Comparable to Bone Fiducials for Registration When Planning Navigation-assisted Musculoskeletal Tumor Resections in a Cadaveric Simulated Tumor Model?
  • Rodolfo Zamora
  • Stephanie E Punt
  • Claudia Christman-Skieller
  • Cengiz Yildirim
  • John C Shapton
  • Ernest U Conrad
  • Clin. Orthop. Relat. Res..2019 Dec;477(12):2692-2701. 00003086-201912000-00018. doi: 10.1097/CORR.0000000000000924.

アムバチニブ誘導体であるN-(2H-1,3-ベンゾジオキソール-5-イル)-4-{チエノ3,2-dピリミジン-4-イル}ピペラジン-1-カルボキサミドは、グルコース飢餓下でミトコンドリアを阻害し、腫瘍細胞を死滅させる

The Amuvatinib Derivative, N-(2H-1,3-Benzodioxol-5-yl)-4-{thieno[3,2-d]pyrimidin-4-yl}piperazine-1-carboxamide, Inhibits Mitochondria and Kills Tumor Cells under Glucose Starvation.
  • Ran Marciano
  • Hila Ben David
  • Barak Akabayov
  • Barak Rotblat
  • Int J Mol Sci.2020 Feb;21(3). E1041. doi: 10.3390/ijms21031041.Epub 2020-02-04.

後根神経節における小胞体ストレスは大導電性カリウムチャネルを制御し、多発性硬化症モデルにおける疼痛に寄与している

Endoplasmic reticulum stress in the dorsal root ganglia regulates large-conductance potassium channels and contributes to pain in a model of multiple sclerosis.
  • Muhammad Saad Yousuf
  • Samira Samtleben
  • Shawn M Lamothe
  • Timothy N Friedman
  • Ana Catuneanu
  • Kevin Thorburn
  • Mansi Desai
  • Gustavo Tenorio
  • Geert J Schenk
  • Klaus Ballanyi
  • Harley T Kurata
  • Thomas Simmen
  • Bradley J Kerr
  • FASEB J..2020 Jul;doi: 10.1096/fj.202001163R.Epub 2020-07-17.

インスリン投与によるラットにおける2型糖尿病誘発性大動脈超構造変化の抑制：血管障害バイオマーカーとの関連

Suppression of type 2 diabetes mellitus-induced aortic ultrastructural alterations in rats by insulin: an association of vascular injury biomarkers.
  • Norah M Alzamil
  • Amal F Dawood
  • Peter W Hewett
  • Ismaeel Bin-Jaliah
  • Abdullah S Assiri
  • Dina H Abdel Kader
  • Refaat A Eid
  • Mohamed A Haidara
  • Bahjat Al-Ani
  • Ultrastruct Pathol.2020 Jun;:1-8. doi: 10.1080/01913123.2020.1780362.Epub 2020-06-13.

ドミナント側椎骨動脈を包囲する頭蓋椎体接合部の硬膜外腫瘍に対するコイル塞栓術を用いた全摘出術の成功例．

[Successful Total Resection with Preceding Arterial Coil Embolization of Intradural Extramedullary Tumor at Craniovertebral Junction Encasing Dominant-side Vertebral Artery].
  • Ryota Tatezawa
  • Motoyuki Iwasaki
  • Kazutoshi Hida
  • Toshiya Osanai
  • Masahito Kawabori
  • Rena Morita
  • Tomohiro Yamauchi
  • Yoshimasa Niiya
  • Koji Furukawa
  • Takeo Abumiya
  • Shoji Mabuchi
  • No Shinkei Geka.2020 Jun;48(6):509-514. 1436204220. doi: 10.11477/mf.1436204220.

スタティックを STAT3 阻害剤としてナノ構造脂質担体（NLC）に配合することで、メラノーマ癌細胞におけるドキソルビシンの有効性を向上させることができた

Formulation of Stattic as STAT3 inhibitor in nanostructured lipid carriers (NLCs) enhances efficacy of doxorubicin in melanoma cancer cells.
  • Jamal Mohammadian
  • Shiva Mahmoudi
  • Pirouz Pourmohammad
  • Mohammad Pirouzpanah
  • Fatemeh Salehnia
  • Nazila Fathi Maroufi
  • Nasser Samadi
  • Mehdi Sabzichi
  • Naunyn Schmiedebergs Arch. Pharmacol..2020 Jul;10.1007/s00210-020-01942-x. doi: 10.1007/s00210-020-01942-x.Epub 2020-07-11.

一次放射線治療後の局所再発前立腺がんに対する凍結手術と一次アンドロゲン遮断療法の比較。傾向をマッチさせた生存率の解析

Cryosurgery Versus Primary Androgen Deprivation Therapy for Locally Recurrent Prostate Cancer After Primary Radiotherapy: A Propensity-Matched Survival Analysis.
  • Glenn Bauman
  • Keyue Ding
  • Joseph Chin
  • Shiva Nair
  • Alessandra Iaboni
  • Juanita Crook
  • Laurence Klotz
  • David Dearnaley
  • Eric Horwitz
  • Christopher O'Callaghan
  • Cureus.2020 May;12(5):e7983. doi: 10.7759/cureus.7983.Epub 2020-05-06.

スリランカにおけるマイコバクテリウム結核とマイコバクテリウム・レプラエの共存：症例シリーズ

Coexistence of mycobacterial infections - Mycobacterium tuberculosis and Mycobacterium leprae - in Sri Lanka: a case series.
  • B S D P Keragala
  • H M M T B Herath
  • G H D C Janapriya
  • S Vanitha
  • Thanushah Balendran
  • Thavarajah Janani
  • T S Keragala
  • C N Gunasekera
  • J Med Case Rep.2020 Jul;14(1):101. 10.1186/s13256-020-02413-w. doi: 10.1186/s13256-020-02413-w.Epub 2020-07-16.

MYCによるMEIS1のダウンレギュレーションは、HOXB13の発現とAR活性の上昇を介して前立腺癌の発生を媒介しています

MEIS1 down-regulation by MYC mediates prostate cancer development through elevated HOXB13 expression and AR activity.
  • Nichelle C Whitlock
  • Shana Y Trostel
  • Scott Wilkinson
  • Nicholas T Terrigino
  • S Thomas Hennigan
  • Ross Lake
  • Nicole V Carrabba
  • Rayann Atway
  • Elizabeth D Walton
  • Berkley E Gryder
  • Brian J Capaldo
  • Huihui Ye
  • Adam G Sowalsky
  • Oncogene.2020 Jul;10.1038/s41388-020-01389-7. doi: 10.1038/s41388-020-01389-7.Epub 2020-07-17.

アルファルファ（Medicago sativa L.）の結節した根では、塩分濃度と洪水の両方のストレス下で一酸化窒素の産生がエネルギー状態の維持に関与している

Nitric oxide production is involved in maintaining energy state in Alfalfa (Medicago sativa L.) nodulated roots under both salinity and flooding.
  • Fatma Aridhi
  • Hajer Sghaier
  • Allyzée Gaitanaros
  • Ayda Khadri
  • Samira Aschi-Smiti
  • Renaud Brouquisse
  • Planta.2020 Jul;252(2):22. 10.1007/s00425-020-03422-1. doi: 10.1007/s00425-020-03422-1.Epub 2020-07-16.

エスモロールは、ブタの出血性ショックモデルにおける大動脈の蘇生的血管内バルーン閉塞術（REBOA）によって誘発される心筋損傷を軽減する

Esmolol reduces myocardial injury induced by resuscitative endovascular balloon occlusion of the aorta (REBOA) in a porcine model of hemorrhagic shock.
  • Guillaume L Hoareau
  • Carl A Beyer
  • Connor M Caples
  • Marguerite W Spruce
  • Zachary Gilbert
  • J Kevin Grayson
  • Lucas P Neff
  • Timothy K Williams
  • M Austin Johnson
  • Injury.2020 Jul;S0020-1383(20)30564-7. doi: 10.1016/j.injury.2020.07.005.Epub 2020-07-03.

一次PCI時の難治性冠動脈無血流STEMI患者に対するエピネフリン冠動脈内投与の有効性と安全性：RESTORE観察研究

Efficacy and safety of intracoronary epinephrine versus conventional treatments alone in STEMI patients with refractory coronary no-reflow during primary PCI: The RESTORE observational study.
  • Eliano P Navarese
  • Lara Frediani
  • David E Kandzari
  • Gianluca Caiazzo
  • Angela Marella Cenname
  • Bernardo Cortese
  • Tommaso Piva
  • Andi Muçaj
  • Carlo Tumscitz
  • Francesco Paparoni
  • Claudio Larosa
  • Teodoro Bisceglia
  • Mila Menozzi
  • Paul A Gurbel
  • Jacek Kubica
  • Catheter Cardiovasc Interv.2020 Jul;doi: 10.1002/ccd.29113.Epub 2020-07-17.

高インスリン血症は、INS/IRS-1/PI3-K/Aktシグナル伝達経路を介してOLETFラットのIGTステージで腎臓病を引き起こすことができます

Hyperinsulinemia Can Cause Kidney Disease in the IGT Stage of OLETF Rats via the INS/IRS-1/PI3-K/Akt Signaling Pathway.
  • Yi Zhang
  • Shaohua Yang
  • Xiao Cui
  • Juhong Yang
  • Miaoyan Zheng
  • Junya Jia
  • Fei Han
  • Xiaoyun Yang
  • Jingyu Wang
  • Zhenhong Guo
  • Bai Chang
  • Baocheng Chang
  • J Diabetes Res.2019;2019:4709715. doi: 10.1155/2019/4709715.Epub 2019-10-13.

中等度から重度の大うつ病性障害におけるスコポラミン増強の筋肉内投与の効果：無作為化二重盲検プラセボ対照試験

The effects of intramuscular administration of scopolamine augmentation in moderate to severe major depressive disorder: a randomized, double-blind, placebo-controlled trial.
  • Jingjing Zhou
  • Jian Yang
  • Xuequan Zhu
  • Tarek Zghoul
  • Lei Feng
  • Runsen Chen
  • Gang Wang
  • Ther Adv Psychopharmacol.2020;10:2045125320938556. 10.1177_2045125320938556. doi: 10.1177/2045125320938556.Epub 2020-07-01.

多価金属カチオン製剤やポリカチオンポリマー製剤との同時投与により、キレートを介したラルテグラビルの吸収が阻害される

Concurrent administration with multivalent metal cation preparations or polycationic polymer preparations inhibits the absorption of raltegravir via its chelation.
  • Yuki Enoki
  • Norihiro Suzuki
  • Motoyasu Ito
  • Eri Uchiyama
  • Nagomi Kishi
  • Chihiro Ito
  • Yuki Kitahiro
  • Kazuki Sakamoto
  • Kazuaki Taguchi
  • Yuta Yokoyama
  • Junko Kizu
  • Kazuaki Matsumoto
  • J. Pharm. Pharmacol..2020 Jul;doi: 10.1111/jphp.13330.Epub 2020-07-13.

関節鏡下肩関節手術に対するインタースカラセンブロック、前上腕神経ブロック、後上腕神経ブロックの呼吸・鎮痛効果を比較した無作為化比較試験

Randomized, controlled trial comparing respiratory and analgesic effects of interscalene block, anterior suprascapular, and posterior suprascapular nerve block for arthroscopic shoulder surgeries.
  • Yean Chin Lim
  • Zhao Kun Koo
  • Vivian W Ho
  • See Seong Chang
  • Shivani Manohara
  • Qian Jun Tong
  • Korean J Anesthesiol.2020 Jul;kja.20141. doi: 10.4097/kja.20141.Epub 2020-07-16.

コモンボトルノーズイルカ（Tursiops truncatus）におけるモノフィラメントラインの絡み合いの事例研究：絡み合い、絡み合いが外れ、その後の死亡

A case study of monofilament line entanglement in a common bottlenose dolphin (Tursiops truncatus): entanglement, disentanglement, and subsequent death.
  • Wendy Marks
  • Steve Burton
  • Elizabeth Stratton
  • Eric Zolman
  • George Biedenbach
  • Annie Page-Karjian
  • BMC Vet. Res..2020 Jun;16(1):223. 10.1186/s12917-020-02436-x. doi: 10.1186/s12917-020-02436-x.Epub 2020-06-30.

KIT経路のアップレギュレーションは急性骨髄性白血病におけるダサチニブの有効性を予測する

KIT pathway upregulation predicts dasatinib efficacy in acute myeloid leukemia.
  • Disha Malani
  • Bhagwan Yadav
  • Ashwini Kumar
  • Swapnil Potdar
  • Mika Kontro
  • Matti Kankainen
  • Komal K Javarappa
  • Kimmo Porkka
  • Maija Wolf
  • Tero Aittokallio
  • Krister Wennerberg
  • Caroline A Heckman
  • Astrid Murumägi
  • Olli Kallioniemi
  • Leukemia.2020 Jul;10.1038/s41375-020-0978-7. doi: 10.1038/s41375-020-0978-7.Epub 2020-07-17.

ボディイメージは、新米母親の体重増加の抑うつ効果を媒介し、特にすでに肥満状態にある女性の場合：ノルウェー母子コホート研究からの証拠

Body image mediates the depressive effects of weight gain in new mothers, particularly for women already obese: evidence from the Norwegian Mother and Child Cohort Study.
  • Seung-Yong Han
  • Alexandra A Brewis
  • Amber Wutich
  • BMC Public Health.2016 07;16:664. 10.1186/s12889-016-3363-8. doi: 10.1186/s12889-016-3363-8.Epub 2016-07-29.

ポリフェノールの免疫調節機能：がん免疫における意味合い

The immunoregulatory function of polyphenols: implications in cancer immunity.
  • José Tarcísio Giffoni de Carvalho
  • Debora Da Silva Baldivia
  • David Tsuyoshi Hiramatsu de Castro
  • Helder Freitas Dos Santos
  • Cintia Miranda Dos Santos
  • Alex Santos Oliveira
  • Tamaeh Monteiro Alfredo
  • Kellen Natalice Vilharva
  • Kely de Picoli Souza
  • Edson Lucas Dos Santos
  • J. Nutr. Biochem..2020 May;85:108428. S0955-2863(20)30460-5. doi: 10.1016/j.jnutbio.2020.108428.Epub 2020-05-26.

男性の健康に関するトピックに焦点を当てた、ターゲットを絞ったエビデンスに基づいたインターネット・ストリーミング・ビデオ介入の人気と世界的なリーチ

Popularity and worldwide reach of targeted, evidence-based internet streaming video interventions focused on men's health topics.
  • Kassandra E Zaila
  • Vadim Osadchiy
  • Ashley S Anderson
  • Sriram V Eleswarapu
  • Jesse N Mills
  • Transl Androl Urol.2020 Jun;9(3):1374-1381. tau-09-03-1374. doi: 10.21037/tau-20-580.

体重減少ダイエットで肥満とプレ更年期女性の体重減少なしでアナンダミドと2-AGの空腹時レベルを減少させるホエイプロテインサプリメント

Whey protein supplementation reducing fasting levels of anandamide and 2-AG without weight loss in pre-menopausal women with obesity on a weight-loss diet.
  • Fatemeh Haidari
  • Vahideh Aghamohammadi
  • Majid Mohammadshahi
  • Kambiz Ahmadi-Angali
  • Mohammad Asghari-Jafarabadi
  • Trials.2020 Jul;21(1):657. 10.1186/s13063-020-04586-7. doi: 10.1186/s13063-020-04586-7.Epub 2020-07-17.

また、BR 欠損変異体の比較リン酸化プロテオーム解析により、GhSK13 が綿繊維の発育を制御する上で重要な役割を果たしていることが明らかになりました

Comparative phosphoproteomic analysis of BR-defective mutant reveals a key role of GhSK13 in regulating cotton fiber development.
  • Lingling Wang
  • Han Cheng
  • Fangjie Xiong
  • Shuya Ma
  • Lei Zheng
  • Yun Song
  • Kexuan Deng
  • Huanhuan Wu
  • Fuguang Li
  • Zuoren Yang
  • Sci China Life Sci.2020 Jul;10.1007/s11427-020-1728-9. doi: 10.1007/s11427-020-1728-9.Epub 2020-07-03.

極端な高尿酸血症は、透析患者の感染症関連死の危険因子である：多施設プロスペクティブコホート研究

Extreme hyperuricemia is a risk factor for infection-related deaths in incident dialysis patients: a multicenter prospective cohort study.
  • Hiroyuki Yoshida
  • Daijo Inaguma
  • Eri Koshi-Ito
  • Soshiro Ogata
  • Akimitsu Kitagawa
  • Kazuo Takahashi
  • Shigehisa Koide
  • Hiroki Hayashi
  • Midori Hasegawa
  • Yukio Yuzawa
  • Naotake Tsuboi
  • Ren Fail.2020 Nov;42(1):646-655. doi: 10.1080/0886022X.2020.1788582.

制御された薬物送達のための温度感受性生体適合性構造としての磁気的に活性なpNIPAMナノシステム

Magnetically active pNIPAM nanosystems as temperature-sensitive biocompatible structures for controlled drug delivery.
  • Beatriz Garcia-Pinel
  • Alicia Ortega-Rodríguez
  • Cristina Porras-Alcalá
  • Laura Cabeza
  • Rafael Contreras-Cáceres
  • Raul Ortiz
  • Amelia Díaz
  • Ana Moscoso
  • Francisco Sarabia
  • José Prados
  • Juan M López-Romero
  • Consolación Melguizo
  • Artif Cells Nanomed Biotechnol.2020 Dec;48(1):1022-1035. doi: 10.1080/21691401.2020.1773488.

セルロースナノファイバー基板上に不均一に集積されたフレキシブルマイクロ波増幅器

Heterogeneously integrated flexible microwave amplifiers on a cellulose nanofibril substrate.
  • Huilong Zhang
  • Jinghao Li
  • Dong Liu
  • Seunghwan Min
  • Tzu-Hsuan Chang
  • Kanglin Xiong
  • Sung Hyun Park
  • Jisoo Kim
  • Yei Hwan Jung
  • Jeongpil Park
  • Juhwan Lee
  • Jung Han
  • Linda Katehi
  • Zhiyong Cai
  • Shaoqin Gong
  • Zhenqiang Ma
  • Nat Commun.2020 Jun;11(1):3118. 10.1038/s41467-020-16957-4. doi: 10.1038/s41467-020-16957-4.Epub 2020-06-19.

側方筋膜裂断裂はACL損傷によく見られる。600人の連続した患者の関節鏡下断裂パターンに基づく分類システム

Lateral Meniscal Oblique Radial Tears Are Common With ACL Injury: A Classification System Based on Arthroscopic Tear Patterns in 600 Consecutive Patients.
  • Aaron J Krych
  • Matthew D LaPrade
  • Corey S Cook
  • Devin Leland
  • Lucas K Keyt
  • Michael J Stuart
  • Patrick A Smith
  • Orthop J Sports Med.2020 May;8(5):2325967120921737. 10.1177_2325967120921737. doi: 10.1177/2325967120921737.Epub 2020-05-19.

地理的に異なる種類のプロポリスとブラックコットンウッド樹脂の口腔内連鎖球菌、膣内微生物、植物病原性フザリウム種に対するフェノール組成と生物学的活性

Phenolic composition and biological activities of geographically different type of propolis and black cottonwood resins against oral streptococci, vaginal microbiota and phytopathogenic Fusarium species.
  • P Ristivojević
  • T Stević
  • M Starović
  • S Pavlović
  • M M Özcan
  • T Berić
  • I Dimkić
  • J. Appl. Microbiol..2020 Aug;129(2):296-310. doi: 10.1111/jam.14633.Epub 2020-03-22.

SARS-CoV-2の不活化ワクチン候補の開発

Development of an inactivated vaccine candidate for SARS-CoV-2.
  • Qiang Gao
  • Linlin Bao
  • Haiyan Mao
  • Lin Wang
  • Kangwei Xu
  • Minnan Yang
  • Yajing Li
  • Ling Zhu
  • Nan Wang
  • Zhe Lv
  • Hong Gao
  • Xiaoqin Ge
  • Biao Kan
  • Yaling Hu
  • Jiangning Liu
  • Fang Cai
  • Deyu Jiang
  • Yanhui Yin
  • Chengfeng Qin
  • Jing Li
  • Xuejie Gong
  • Xiuyu Lou
  • Wen Shi
  • Dongdong Wu
  • Hengming Zhang
  • Lang Zhu
  • Wei Deng
  • Yurong Li
  • Jinxing Lu
  • Changgui Li
  • Xiangxi Wang
  • Weidong Yin
  • Yanjun Zhang
  • Chuan Qin
  • Science.2020 07;369(6499):77-81. science.abc1932. doi: 10.1126/science.abc1932.Epub 2020-05-06.

ミトコンドリアORFansの多様性は、淡水イガイ科（Bivalvia: Unionida）の間でミトコンドリアの二重一親遺伝の仕組みが異なる可能性を示唆している

Variability of mitochondrial ORFans hints at possible differences in the system of doubly uniparental inheritance of mitochondria among families of freshwater mussels (Bivalvia: Unionida).
  • Davide Guerra
  • Manuel Lopes-Lima
  • Elsa Froufe
  • Han Ming Gan
  • Paz Ondina
  • Rafaela Amaro
  • Michael W Klunzinger
  • Claudia Callil
  • Vincent Prié
  • Arthur E Bogan
  • Donald T Stewart
  • Sophie Breton
  • BMC Evol. Biol..2019 12;19(1):229. 10.1186/s12862-019-1554-5. doi: 10.1186/s12862-019-1554-5.Epub 2019-12-19.

ドキシサイクリン系高分子ナノ粒子の合成と抗腫瘍活性.固形エルリッヒ癌における腫瘍アポトーシスへの影響

Synthesis and Antitumor Activity of Doxycycline Polymeric Nanoparticles: Effect on Tumor Apoptosis in Solid Ehrlich Carcinoma.
  • Ahmed R Gardouh
  • Mohammed A Attia
  • Eman T Enan
  • Alaaeldeen M Elbahaie
  • Rania A Fouad
  • Mohamed El-Shafey
  • Amal M Youssef
  • Suliman Y Alomar
  • Zinab Abd-Elhady Ali
  • Sawsan A Zaitone
  • Mona K E Qushawy
  • Molecules.2020 Jul;25(14). E3230. doi: 10.3390/molecules25143230.Epub 2020-07-15.

同種造血幹細胞移植後に多発性硬化症様の再発性再発性脳脊髄炎を発症した1例と発表された文献のレビュー

A Case of Multiple Sclerosis-Like Relapsing Remitting Encephalomyelitis Following Allogeneic Hematopoietic Stem Cell Transplantation and a Review of the Published Literature.
  • Joyutpal Das
  • Atta Gill
  • Christine Lo
  • Natalie Chan-Lam
  • Siân Price
  • Stephen B Wharton
  • Helen Jessop
  • Basil Sharrack
  • John A Snowden
  • Front Immunol.2020;11:668. doi: 10.3389/fimmu.2020.00668.Epub 2020-05-05.

インフルエンザに感染すると、内在性ビフィドバクテリウム・アニマリスの腸内集団が拡大し、マウスを感染から保護します

Influenza infection elicits an expansion of gut population of endogenous Bifidobacterium animalis which protects mice against infection.
  • Qiang Zhang
  • Jin Hu
  • Jia-Wu Feng
  • Xiao-Tong Hu
  • Ting Wang
  • Wen-Xiao Gong
  • Kun Huang
  • Yi-Xiong Guo
  • Zhong Zou
  • Xian Lin
  • Run Zhou
  • Yu-Qi Yuan
  • An-Ding Zhang
  • Hong Wei
  • Gang Cao
  • Chen Liu
  • Ling-Ling Chen
  • Mei-Lin Jin
  • Genome Biol..2020 04;21(1):99. 10.1186/s13059-020-02007-1. doi: 10.1186/s13059-020-02007-1.Epub 2020-04-28.

2型糖尿病治療のための新規腎ナトリウム依存性グルコースコトランスポーター2（SGLT2）阻害剤としての6-デオキシO-スピロケタールC-アリルグルコシドの設計、合成、生物学的評価

Design, synthesis and biological evaluation of 6-deoxy O-spiroketal C-arylglucosides as novel renal sodium-dependent glucose cotransporter 2 (SGLT2) inhibitors for the treatment of type 2 diabetes.
  • Yibing Wang
  • Yang Lou
  • Jiang Wang
  • Dan Li
  • Hui Chen
  • Tiannan Zheng
  • Chunmei Xia
  • Xiaohan Song
  • Tiancheng Dong
  • Jingya Li
  • Jia Li
  • Hong Liu
  • Eur J Med Chem.2019 Oct;180:398-416. S0223-5234(19)30653-1. doi: 10.1016/j.ejmech.2019.07.032.Epub 2019-07-10.

Thermomyces lanuginosus由来リパーゼの新しいキトサンベースのヘテロ機能性支持体上での固定化の改善。混合イオン交換と疎水性相互作用

Improved immobilization of lipase from Thermomyces lanuginosus on a new chitosan-based heterofunctional support: Mixed ion exchange plus hydrophobic interactions.
  • Nicole S Okura
  • Guilherme J Sabi
  • Marcela C Crivellenti
  • Raphael A B Gomes
  • Roberto Fernandez-Lafuente
  • Adriano A Mendes
  • Int. J. Biol. Macromol..2020 Jul;163:550-561. S0141-8130(20)33766-1. doi: 10.1016/j.ijbiomac.2020.07.021.Epub 2020-07-06.

記述輸入された重症マラリア原虫の成人における急性呼吸窮迫症候群（ARDS）：ポルトガルの第三療養病院における10年間の研究

Descriptive Acute Respiratory Distress Syndrome (ARDS) in adults with imported severe Plasmodium falciparum malaria: A 10 year-study in a Portuguese tertiary care hospital.
  • Luísa Graça
  • Isabel Gomes Abreu
  • Ana Sofia Santos
  • Luís Graça
  • Paulo Figueiredo Dias
  • Maria Lurdes Santos
  • PLoS ONE.2020;15(7):e0235437. PONE-D-20-02362. doi: 10.1371/journal.pone.0235437.Epub 2020-07-09.

限局性腎腫瘤に対する腎部分切除術後の周術期成績および手術マージンに及ぼす切除術の影響。プロスペクティブな多施設共同研究

Impact of Resection Technique on Perioperative Outcomes and Surgical Margins after Partial Nephrectomy for Localized Renal Masses: A Prospective Multicenter Study.
  • Andrea Minervini
  • Riccardo Campi
  • Brian R Lane
  • Ottavio De Cobelli
  • Francesco Sanguedolce
  • Georgios Hatzichristodoulou
  • Alessandro Antonelli
  • Sabrina Noyes
  • Andrea Mari
  • Oscar Rodriguez-Faba
  • Frank X Keeley
  • Johan Langenhuijsen
  • Gennaro Musi
  • Tobias Klatte
  • Marco Roscigno
  • Bulent Akdogan
  • Maria Furlan
  • Nihat Karakoyunlu
  • Martin Marszalek
  • Umberto Capitanio
  • Alessandro Volpe
  • Sabine Brookman-May
  • Jürgen E Gschwend
  • Marc C Smaldone
  • Robert G Uzzo
  • Marco Carini
  • Alexander Kutikov
  • J. Urol..2020 03;203(3):496-504. doi: 10.1097/JU.0000000000000591.Epub 2019-10-14.

TRPV1チャネルの活性化は、ポッドサイトにおける小胞体とミトコンドリアの接触を阻害することにより、糖尿病性腎症に拮抗する

Activation of TRPV1 channel antagonizes diabetic nephropathy through inhibiting endoplasmic reticulum-mitochondria contact in podocytes.
  • Xiao Wei
  • Xing Wei
  • Zongshi Lu
  • Li Li
  • Yingru Hu
  • Fang Sun
  • Yanli Jiang
  • Huan Ma
  • Hongting Zheng
  • Gangyi Yang
  • Daoyan Liu
  • Peng Gao
  • Zhiming Zhu
  • Metab. Clin. Exp..2020 04;105:154182. S0026-0495(20)30046-9. doi: 10.1016/j.metabol.2020.154182.Epub 2020-02-13.

非侵襲的な線維化マーカーであるFibrosis-4指数は、大腸がん肝転移に対する肝切除術後の生存率を予測する

Fibrosis-4 Index, a Noninvasive Fibrosis Marker, Predicts Survival Outcomes After Hepatectomy for Colorectal Cancer Liver Metastases.
  • Takahiko Akiyama
  • Yuji Miyamoto
  • Katsunori Imai
  • Yoichi Yamashita
  • Daichi Nomoto
  • Nobuya Daitoku
  • Yuki Sakamoto
  • Yuki Kiyozumi
  • Ryuma Tokunaga
  • Kojiro Eto
  • Kazuto Harada
  • Yukiharu Hiyoshi
  • Masaaki Iwatsuki
  • Yohei Nagai
  • Shiro Iwagami
  • Yoshifumi Baba
  • Naoya Yoshida
  • Hideo Baba
  • Ann. Surg. Oncol..2020 Jul;10.1245/s10434-020-08828-5. doi: 10.1245/s10434-020-08828-5.Epub 2020-07-09.

チロシンキナーゼ阻害薬は、転移性胃腸間質腫瘍患者の生存成績を有意に改善した：多施設コホート研究

Tyrosine kinase inhibitors significantly improved survival outcomes in patients with metastatic gastrointestinal stromal tumour: a multi-institutional cohort study.
  • A Deruchie Tan
  • K Willemsma
  • A MacNeill
  • K DeVries
  • A Srikanthan
  • C McGahan
  • T Hamilton
  • H Li
  • C D Blanke
  • C E Simmons
  • Curr Oncol.2020 Jun;27(3):e276-e282. conc-27-e276. doi: 10.3747/co.27.5869.Epub 2020-06-01.

間葉系上皮性卵巣癌細胞におけるLY75の抑制は、同所性異種移植マウスモデルにおいて、腫瘍の発生、広がりおよび治療抵抗性の向上と関連した安定なハイブリッドEOC細胞表現型を生成する

LY75 Suppression in Mesenchymal Epithelial Ovarian Cancer Cells Generates a Stable Hybrid EOC Cellular Phenotype, Associated with Enhanced Tumor Initiation, Spreading and Resistance to Treatment in Orthotopic Xenograft Mouse Model.
  • Sadia Mehdi
  • Elizabeth Macdonald
  • Kristianne Galpin
  • David A Landry
  • Galaxia Rodriguez
  • Barbara Vanderhyden
  • Dimcho Bachvarov
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Dientamoeba fragilis治療においてパロマイシンはメトロニダゾールよりも優れている

Paromomycin is superior to metronidazole in Dientamoeba fragilis treatment.
  • Ander Burgaña
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  • Stanislav Zlatanov Yordanov
  • Rabee Kazan
  • A Mauricio Pérez Ortiz
  • Cristina Castillo Ramos
  • Christian Garavito Hernández
  • Miriam Molina Rivero
  • Alessandra Queiroga Gonçalves
  • Emma Padilla
  • Josefa Pérez
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アザチオプリン、塩酸クロニジン、クロピドグレル二硫酸塩、塩酸エタンブトール、グリセオフルビン、塩酸ヒドラジン、ニトロフラントインおよびチオグアニン経口懸濁液の安定性

Stability of Azathioprine, Clonidine Hydrochloride, Clopidogrel Bisulfate, Ethambutol Hydrochloride, Griseofulvin, Hydralazine Hydrochloride, Nitrofurantoin, and Thioguanine Oral Suspensions Compounded with SyrSpend SF pH4.
  • Hudson Polonini
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  • Carolina Neves Cunha
  • Anderson de Oliveira Ferreira
  • Korina Anagnostou
  • Eli Dijkers
  • Int J Pharm Compd.2020 May-Jun;24(3):252-262.

乳酸脱水素酵素と軽度のCOVID-19患者の悪化感受性：多施設非ステッド症例対照研究

Lactate dehydrogenase and susceptibility to deterioration of mild COVID-19 patients: a multicenter nested case-control study.
  • Jichan Shi
  • Yang Li
  • Xian Zhou
  • Qiran Zhang
  • Xinchun Ye
  • Zhengxing Wu
  • Xiangao Jiang
  • Hongying Yu
  • Lingyun Shao
  • Jing-Wen Ai
  • Haocheng Zhang
  • Bin Xu
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  • Wenhong Zhang
  • BMC Med.2020 06;18(1):168. 10.1186/s12916-020-01633-7. doi: 10.1186/s12916-020-01633-7.Epub 2020-06-03.

生理活性キナクリンと銀のハイブリッドナノ粒子による口腔癌幹細胞の細胞毒性と血管新生阻害の強化」の訂正。癌細胞の細胞毒性の増強：塩基切開修復カスケードの示唆」の訂正

Correction to "Enhancement of Cytotoxicity and Inhibition of Angiogenesis in Oral Cancer Stem Cells by a Hybrid Nanoparticle of Bioactive Quinacrine and Silver: Implication of Base Excision Repair Cascade".
  • Shakti Ranjan Satapathy
  • Sumit Siddharth
  • Dipon Das
  • Anmada Nayak
  • Chanakya Nath Kundu
  • Mol. Pharm..2020 Jul;doi: 10.1021/acs.molpharmaceut.0c00706.Epub 2020-07-17.

ホスホグルコムターゼ 1 欠損症（PGM1-CDG）の国際的コンセンサスガイドライン：診断、フォローアップおよび管理

International consensus guidelines for phosphoglucomutase 1 deficiency (PGM1-CDG): diagnosis, follow-up and management.
  • Ruqaiah Altassan
  • Silvia Radenkovic
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  • Rita Barone
  • Sandra Brasil
  • Anna Cechova
  • David Coman
  • Sarah Donoghue
  • Kristina Falkenstein
  • Vanessa Ferreira
  • Carlos Ferreira
  • Agata Fiumara
  • Rita Francsico
  • Hudson Freeze
  • Stephanie Grunewald
  • Tomas Honzik
  • Jaak Jaeken
  • Donna Krasnewich
  • Christina Lam
  • Joy Lee
  • Dirk Lefeber
  • Dorinda Marques-da-Silva
  • Carlota Pascoal
  • Dulce Quelhas
  • Kimiyo M Raymond
  • Daisy Rymen
  • Malgorzata Seroczynska
  • Mercedes Serrano
  • Jolanta Sykut-Cegielska
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  • Paula Videira
  • Nicol Voermans
  • Peter Witters
  • Eva Morava
  • J. Inherit. Metab. Dis..2020 Jul;doi: 10.1002/jimd.12286.Epub 2020-07-18.

経皮的経皮的経皮的血管形成術後の表在性大腿動脈裂孔の評価：カラーコードされたsummation画像と単色デジタルサブトラクション血管造影

Evaluation of superficial femoral artery-lesions after percutaneous transluminal angioplasty: color-coded summation images vs. monochromatic digital subtraction angiography.
  • Anne Marie Augustin
  • Irina Thein
  • Nicole Rickert
  • Thorsten Klink
  • Thorsten Alexander Bley
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四面体DNAナノ構造体をベースとした多機能複合体の設計、作製、およびドラッグデリバリーおよび生物医学的治療への応用

Design, fabrication and applications of tetrahedral DNA nanostructure-based multifunctional complexes in drug delivery and biomedical treatment.
  • Tao Zhang
  • Taoran Tian
  • Ronghui Zhou
  • Songhang Li
  • Wenjuan Ma
  • Yuxin Zhang
  • Nanxin Liu
  • Sirong Shi
  • Qianshun Li
  • Xueping Xie
  • Yichen Ge
  • Mengting Liu
  • Qi Zhang
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  • Xiaoxiao Cai
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ジンバブエにおける多剤耐性およびリファンピシン耐性結核の治療成績：2010年から2015年の間に治療を開始した患者のコホート解析

Treatment outcomes of multi drug resistant and rifampicin resistant Tuberculosis in Zimbabwe: A cohort analysis of patients initiated on treatment during 2010 to 2015.
  • Ronnie Matambo
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  • Pruthu Thekkur
  • Charles Sandy
  • Sungano Mharakurwa
  • Talent Makoni
  • Ronald Ncube
  • Kelvin Charambira
  • Christopher Zishiri
  • Mkhokheli Ngwenya
  • Saziso Nyathi
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  • Elliot Chikaka
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多剤耐性結核患者における体格指数の変化のプロファイルの違い：レトロスペクティブコホート研究

Different profiles of body mass index variation among patients with multidrug-resistant tuberculosis: a retrospective cohort study.
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  • Boubacar Djelo Diallo
  • Lansana Mady Camara
  • Lucrèce Ahouéfa Nadège Kounoudji
  • Boubacar Bah
  • Fulgence N'Zabintawali
  • Miguel Carlos-Bolumbu
  • Mamadou Hassimiou Diallo
  • Oumou Younoussa Sow
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RECIST 1.1、irRC、iRECIST基準に基づく半自動ソフトウェアによる免疫療法の奏効評価：主観的評価との比較

Response evaluation for immunotherapy through semi-automatic software based on RECIST 1.1, irRC, and iRECIST criteria: comparison with subjective assessment.
  • Ying-Chieh Lai
  • Wen-Cheng Chang
  • Chun-Bing Chen
  • Chi-Liang Wang
  • Yu-Fen Lin
  • Ming-Mo Ho
  • Chi-Yuan Cheng
  • Pei-Wei Huang
  • Chao-Wei Hsu
  • Gigin Lin
  • Acta Radiol.2020 Jul;61(7):983-991. doi: 10.1177/0284185119887588.Epub 2019-11-18.

高齢の非小細胞肺がん患者におけるプラチナ製剤ベースの化学療法。現実の世界で何を期待すべきか

Platinum-Based Chemotherapy in Older Patients with Non-Small Cell Lung Cancer: What to Expect in the Real World.
  • Giacomo Pelizzari
  • Francesco Cortiula
  • Marco Giavarra
  • Michele Bartoletti
  • Camilla Lisanti
  • Vanessa Buoro
  • Monica Cattaneo
  • Ciro Rossetto
  • Simona Rizzato
  • Fabio Puglisi
  • Marianna Macerelli
  • Gianpiero Fasola
  • Alessandro Follador
  • Drugs Aging.2020 Jul;10.1007/s40266-020-00785-8. doi: 10.1007/s40266-020-00785-8.Epub 2020-07-17.

発達期Wntシグナル伝達経路エフェクターβ-カテニン/TCFは、脂質代謝を調節する性ホルモンエストラジオールの肝機能を媒介している

The developmental Wnt signaling pathway effector β-catenin/TCF mediates hepatic functions of the sex hormone estradiol in regulating lipid metabolism.
  • Lili Tian
  • Weijuan Shao
  • Wilfred Ip
  • Zhuolun Song
  • Yasaman Badakhshi
  • Tianru Jin
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新興汚染物質除去のための代替バイオプロセスに関するレビュー

A review on alternative bioprocesses for removal of emerging contaminants.
  • Aline Viancelli
  • William Michelon
  • Paula Rogovski
  • Rafael Dorighello Cadamuro
  • Estêvão Brasiliense de Souza
  • Gislaine Fongaro
  • Aline Frumi Camargo
  • Fábio Sptiza Stefanski
  • Bruno Venturin
  • Thamarys Scapini
  • Charline Bonatto
  • Karina Paula Preczeski
  • Natalia Klanovicz
  • Débora de Oliveira
  • Helen Treichel
  • Bioprocess Biosyst Eng.2020 Jul;10.1007/s00449-020-02410-9. doi: 10.1007/s00449-020-02410-9.Epub 2020-07-17.

PTSD治療のためのMDMA支援心理療法の長期追跡調査結果：6つの第2相試験の縦断的プール解析

Long-term follow-up outcomes of MDMA-assisted psychotherapy for treatment of PTSD: a longitudinal pooled analysis of six phase 2 trials.
  • Lisa Jerome
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  • Julie B Wang
  • Scott Hamilton
  • Berra Yazar-Klosinski
  • Amy Emerson
  • Michael C Mithoefer
  • Rick Doblin
  • Psychopharmacology (Berl.).2020 Aug;237(8):2485-2497. 10.1007/s00213-020-05548-2. doi: 10.1007/s00213-020-05548-2.Epub 2020-06-04.

ヨーロッパ産ガラスウナギ(Anguilla anguilla)の行動とエネルギー関連遺伝子の転写反応にメチル水銀の新たな知見を得た

New insights into methylmercury induced behavioral and energy-related gene transcriptional responses in European glass eel (Anguilla anguilla).
  • Hengtong Liu
  • Amaia Lamarins
  • Jacques Labonne
  • Mathilde Monperrus
  • Pascale Coste
  • Emmanuel Huchet
  • Jacques Rives
  • Iban Seiliez
  • Valérie Bolliet
  • Chemosphere.2020 Sep;255:127020. S0045-6535(20)31213-3. doi: 10.1016/j.chemosphere.2020.127020.Epub 2020-05-10.

新生児のセボフルラン曝露は、その後のセボフルラン曝露の副作用に対する脆弱性の窓を広げ、デシタビン感受性機序を介して海馬の形態を変化させる

Neonatal exposure to sevoflurane expands the window of vulnerability to adverse effects of subsequent exposure to sevoflurane and alters hippocampal morphology via decitabine-sensitive mechanisms.
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  • Lei Lei
  • Ling-Sha Ju
  • Ning Xu
  • Timothy E Morey
  • Nikolaus Gravenstein
  • Jianjun Yang
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早期ホルモン陽性乳癌の女性における手術選択とその後の患者報告満足度の転帰との関係における人種差

Racial differences in the relationship between surgical choice and subsequent patient-reported satisfaction outcomes among women with early-stage hormone-positive breast cancer.
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  • Alexander N Slade
  • Arnethea L Sutton
  • Kandace P McGuire
  • Vanessa Sheppard
  • Breast Cancer Res. Treat..2020 Jul;10.1007/s10549-020-05784-2. doi: 10.1007/s10549-020-05784-2.Epub 2020-07-16.

p32/C1QBPは、ミトコンドリアの機能不全やアポトーシスに関連するミトコンドリアの連結性を維持するために、OMA1依存性のタンパク質分解処理を制御しています

p32/C1QBP regulates OMA1-dependent proteolytic processing of OPA1 to maintain mitochondrial connectivity related to mitochondrial dysfunction and apoptosis.
  • Solhee Noh
  • Sophors Phorl
  • Rema Naskar
  • Kakada Oeum
  • Yuri Seo
  • Eunjung Kim
  • Hee-Seok Kweon
  • Joo-Yong Lee
  • Sci Rep.2020 Jun;10(1):10618. 10.1038/s41598-020-67457-w. doi: 10.1038/s41598-020-67457-w.Epub 2020-06-30.

手術不能な慢性血栓塞栓性肺高血圧症に対するバルーン肺血管形成術：英国での経験

Balloon pulmonary angioplasty for inoperable chronic thromboembolic pulmonary hypertension: the UK experience.
  • Stephen P Hoole
  • John G Coghlan
  • John E Cannon
  • Dolores Taboada
  • Mark Toshner
  • Karen Sheares
  • Andrew John Fletcher
  • Guillermo Martinez
  • Alessandro Ruggiero
  • Nicholas Screaton
  • David Jenkins
  • Joanna Pepke-Zaba
  • Open Heart.2020;7(1):e001144. openhrt-2019-001144. doi: 10.1136/openhrt-2019-001144.Epub 2020-02-27.

胚性幹細胞由来心筋細胞における成熟心室サブタイプの優位性が生体内で増加している

Increased predominance of the matured ventricular subtype in embryonic stem cell-derived cardiomyocytes in vivo.
  • Hajime Ichimura
  • Shin Kadota
  • Toshihide Kashihara
  • Mitsuhiko Yamada
  • Kuniaki Ito
  • Hideki Kobayashi
  • Yuki Tanaka
  • Naoko Shiba
  • Shinichiro Chuma
  • Shugo Tohyama
  • Tatsuichiro Seto
  • Kenji Okada
  • Koichiro Kuwahara
  • Yuji Shiba
  • Sci Rep.2020 Jul;10(1):11883. 10.1038/s41598-020-68373-9. doi: 10.1038/s41598-020-68373-9.Epub 2020-07-17.

資源が限られた環境下で、初期の臨床的特徴と検査的特徴を用いて、重症化リスクの高いデング熱患者を同定すること

Identification of dengue patients with high risk of severe disease, using early clinical and laboratory features, in a resource-limited setting.
  • Madunil A Niriella
  • Isurujith K Liyanage
  • Arundathi Udeshika
  • Kasun V Liyanapathirana
  • Arjuna P De Silva
  • Hithnadura J de Silva
  • Arch. Virol..2020 Jul;10.1007/s00705-020-04720-5. doi: 10.1007/s00705-020-04720-5.Epub 2020-07-02.

ジカの時代における希望と信頼：ブラジルにおける流行の最前線にいる介護者と医療従事者の見解

Hope and trust in times of Zika: the views of caregivers and healthcare workers at the forefront of the epidemic in Brazil.
  • Clarissa Simas
  • Loveday Penn-Kekana
  • Hannah Kuper
  • Tereza Maciel Lyra
  • Maria Elisabeth Lopes Moreira
  • Maria do Socorro Veloso de Albuquerque
  • Thália Velho Barreto de Araújo
  • Ana Paula Lopes de Melo
  • Corina Helena Figueira Mendes
  • Martha Cristina Nunes Moreira
  • Marcos Antonio Ferreira do Nascimento
  • Camila Pimentel
  • Marcia Pinto
  • Sandra Valongueiro
  • Heidi Larson
  • Health Policy Plan.2020 Jul;czaa042. doi: 10.1093/heapol/czaa042.Epub 2020-07-18.

ミエリンオリゴデンドロサイト糖鎖抗体関連視神経炎の臨床的特徴の白人とアジア系人種間での違い

Differences in Clinical Features of Myelin Oligodendrocyte Glycoprotein Antibody-Associated Optic Neuritis in White and Asian Race.
  • Tanyatuth Padungkiatsagul
  • John J Chen
  • Panitha Jindahra
  • Tetsuya Akaishi
  • Toshiyuki Takahashi
  • Ichiro Nakashima
  • Takayuki Takeshita
  • Heather E Moss
  • Am. J. Ophthalmol..2020 Jul;S0002-9394(20)30359-7. doi: 10.1016/j.ajo.2020.07.008.Epub 2020-07-15.

PARP酵素のターゲットエンゲージメントを研究するためのインビトロおよび細胞プローブ

In Vitro and Cellular Probes to Study PARP Enzyme Target Engagement.
  • Tim J Wigle
  • Danielle J Blackwell
  • Laurie B Schenkel
  • Yue Ren
  • W David Church
  • Hetvi J Desai
  • Kerren K Swinger
  • Andrew G Santospago
  • Christina R Majer
  • Alvin Z Lu
  • Mario Niepel
  • Nicholas R Perl
  • Melissa M Vasbinder
  • Heike Keilhack
  • Kevin W Kuntz
  • Cell Chem Biol.2020 Jul;27(7):877-887.e14. S2451-9456(20)30232-4. doi: 10.1016/j.chembiol.2020.06.009.

転移性去勢抵抗性前立腺がんの男性における双極性アンドロゲン療法の多施設共同オープンラベル第II相試験（RESTORE）。アビラテロン投与後とエンザルツアミド投与後のコホートの比較

A Multicohort Open-label Phase II Trial of Bipolar Androgen Therapy in Men with Metastatic Castration-resistant Prostate Cancer (RESTORE): A Comparison of Post-abiraterone Versus Post-enzalutamide Cohorts.
  • Mark C Markowski
  • Hao Wang
  • Rana Sullivan
  • Irina Rifkind
  • Victoria Sinibaldi
  • Michael T Schweizer
  • Benjamin A Teply
  • Nduku Ngomba
  • Wei Fu
  • Michael A Carducci
  • Channing J Paller
  • Catherine H Marshall
  • Mario A Eisenberger
  • Jun Luo
  • Emmanuel S Antonarakis
  • Samuel R Denmeade
  • Eur. Urol..2020 Jul;S0302-2838(20)30471-1. doi: 10.1016/j.eururo.2020.06.042.Epub 2020-07-02.

COVID-19感染症における止血プロファイル

Hemostasis profile in COVID-19 infection.
  • Fernando Barroso Duarte
  • Rosângela Pinheiro Gonçalves Machado
  • Romélia Pinheiro Gonçalves Lemes
  • Isabella Araújo Duarte
  • Beatrice Araújo Duarte
  • Clarissa Maria Gonçalves Machado
  • João Vitor Araújo Duarte
  • Samuel Gonçalves Machado da Rocha
  • Anna Thawanny Gadelha Moura
  • Rosangela de Albuquerque Ribeiro Rodrigues Holanda
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ベトナムの気候変動と健康の脆弱性と適応評価、2018年

Vietnam Climate Change and Health Vulnerability and Adaptation Assessment, 2018.
  • Tran Thi Tuyet Hanh
  • Le Thi Thanh Huong
  • Nguyen Thi Lien Huong
  • Tran Nu Quy Linh
  • Nguyen Huu Quyen
  • Nguyen Thi Trang Nhung
  • Kristie Ebi
  • Nguyen Dinh Cuong
  • Ha Van Nhu
  • Tran Mai Kien
  • Simon Hales
  • Do Manh Cuong
  • Nguyen Thi Thi Tho
  • Luu Quoc Toan
  • Nguyen Ngoc Bich
  • Hoang Van Minh
  • Environ Health Insights.2020;14:1178630220924658. 10.1177_1178630220924658. doi: 10.1177/1178630220924658.Epub 2020-06-22.

水でろ過した赤外線Aおよび可視光（wIRA/VIS）治療は、包接結膜炎のモルモットモデルにおけるクラミジア・キャビア誘発性眼炎症および感染負荷を減少させる

Water-filtered Infrared A and visible light (wIRA/VIS) treatment reduces Chlamydia caviae-induced ocular inflammation and infectious load in a Guinea pig model of inclusion conjunctivitis.
  • Aleksandra Inic-Kanada
  • Marijana Stojanovic
  • Radmila Miljkovic
  • Elisabeth Stein
  • Ana Filipovic
  • Antonia Frohns
  • Nadja Zöller
  • Jasmin Kuratli
  • Talin Barisani-Asenbauer
  • Nicole Borel
  • J. Photochem. Photobiol. B, Biol..2020 Jul;209:111953. S1011-1344(20)30403-6. doi: 10.1016/j.jphotobiol.2020.111953.Epub 2020-07-05.

東南アジアの低中所得国の動物病院が直面するバイオセーフティとバイオセキュリティの課題。タイの事例研究

Biosafety and Biosecurity Challenges Facing Veterinary Diagnostic Laboratories in Lower-Middle Income Countries in Southeast Asia: A Case Study of Thailand.
  • Jarunee Siengsanan-Lamont
  • Somjai Kamolsiripichaiporn
  • Soiratchaneekorn Ruanchaimun
  • Tuangthong Patchimasiri
  • Banjong Jongrakwattana
  • Stuart D Blacksell
  • Appl Biosaf.2019 Dec;24(4):220-230. 10.1177_1535676019869771. doi: 10.1177/1535676019869771.Epub 2019-08-19.

リポ多糖類誘発性急性肺障害は、マウスモデルにおける微小管形成センター（RanBPM）分子発現とミトコンドリア介在性アポトーシスシグナル伝達経路のRan-Binding Proteinの増加と関連している

Lipopolysaccharide-Induced Acute Lung Injury Is Associated with Increased Ran-Binding Protein in Microtubule-Organizing Center (RanBPM) Molecule Expression and Mitochondria-Mediated Apoptosis Signaling Pathway in a Mouse Model.
  • Xiaojing Lv
  • Xiaomin Lu
  • Jiping Zhu
  • Qian Wang
  • Med. Sci. Monit..2020 Jul;26:e923172. 923172. doi: 10.12659/MSM.923172.Epub 2020-07-18.

リツキシマブによる維持療法中に多発性血管炎を伴う肉芽腫症とインフルエンザ肺炎を併発した症例で、偽陰性検査を繰り返した結果、COVID-19の診断が遅れた

Repeated false-negative tests delayed diagnosis of COVID-19 in a case with granulomatosis with polyangiitis under maintenance therapy with rituximab and concomitant influenza pneumonia.
  • Samy Hakroush
  • Jonas Franz
  • Jörg Larsen
  • Peter Korsten
  • Martin Sebastian Winkler
  • Björn Tampe
  • Ann. Rheum. Dis..2020 Jul;annrheumdis-2020-218491. doi: 10.1136/annrheumdis-2020-218491.Epub 2020-07-15.

α2Aアドレナリン受容体欠損症は、急性呼吸窮迫症候群におけるノルエピネフリンレベルの上昇と肺胞マクロファージ活性化の阻害により、リポ多糖類誘発性肺障害を減衰させる

Alpha2A-adrenoceptor deficiency attenuates lipopolysaccharide-induced lung injury by increasing norepinephrine levels and inhibiting alveolar macrophage activation in acute respiratory distress syndrome.
  • Zhukai Cong
  • Dan Li
  • Xiangpeng Lv
  • Cui Yang
  • Qiang Zhang
  • Changyi Wu
  • Zongyu Wang
  • Xi Zhu
  • Clin. Sci..2020 Jul;CS20200586. doi: 10.1042/CS20200586.Epub 2020-07-09.

死細胞のファゴサイトーシスの障害によって引き起こされる組織損傷。肺炎におけるγδT細胞の病因に関与するこれまでにない副作用

Tissue Damage Caused by Impaired Phagocytosis of Dead Cells: A Previously Unrecognized Adverse Effect Contributing to the Pathogenesis of γδ T Cells in Pneumonia.
  • Chiaki Kajiwara
  • Soichiro Kimura
  • Yuriko Tanaka
  • Yoshikiyo Akasaka
  • Yoshikazu Ishii
  • Kazuhiro Tateda
  • Immunohorizons.2020 Jul;4(7):402-414. 4/7/402. doi: 10.4049/immunohorizons.2000054.Epub 2020-07-14.

鉄の鎖のUBC-HCT：アル・マルキらによる「鉄の過負荷はDelayed EngraftmentとAssociated with Delayed Engraftment and Increased Non-Relapse Mortality in Recipients of Umbilical Cord Blood Hematopoietic Cell Transplantation」へのコメント 2020

Chains of Iron in UBC-HCT: Comment on "Iron Overload is Associated with Delayed Engraftment and Increased Non-Relapse Mortality in Recipients of Umbilical Cord Blood Hematopoietic Cell Transplantation" by Al Malki et al. 2020.
  • Mary Ann Knovich
  • Biol. Blood Marrow Transplant..2020 Jul;S1083-8791(20)30441-9. doi: 10.1016/j.bbmt.2020.07.012.Epub 2020-07-15.

薬物ナイーブ」パーキンソン病患者におけるBDNFレベルと黒質変性。I-123-FP-CIT SPECTを用いた"in vivo"研究

BDNF levels and nigrostriatal degeneration in "drug naïve" Parkinson's disease patients. An "in vivo" study using I-123-FP-CIT SPECT.
  • J Hernández-Vara
  • N Sáez-Francàs
  • C Lorenzo-Bosquet
  • M Corominas-Roso
  • G Cuberas-Borròs
  • S Lucas-Del Pozo
  • S Carter
  • M Armengol-Bellapart
  • J Castell-Conesa
  • Parkinsonism Relat. Disord..2020 Jul;78:31-35. S1353-8020(20)30214-5. doi: 10.1016/j.parkreldis.2020.06.037.Epub 2020-07-04.

蝸牛難聴および聴覚神経障害スペクトラム障害における強度の差を評価する客観的尺度としての音響変化複素数の有用性

Utility of Acoustic Change Complex as an Objective Tool to Evaluate Difference Limen for Intensity in Cochlear Hearing Loss and Auditory Neuropathy Spectrum Disorder.
  • Prawin Kumar
  • Himanshu Kumar Sanju
  • Reesha Oovattil Hussain
  • Mechiyanda Kaverappa Ganapathy
  • Niraj Kumar Singh
  • Am J Audiol.2020 Jul;:1-9. doi: 10.1044/2020_AJA-19-00084.Epub 2020-07-06.

ノルウェーの未就学児集団における精神衛生上の問題のスクリーニング。年齢および段階別質問票の検証。Social-emotional（ASQ:SE）

Screening for mental health problems in a Norwegian preschool population. A validation of the ages and stages questionnaire: Social-emotional (ASQ:SE).
  • Kenneth Stensen
  • Frode Stenseng
  • Stian Lydersen
  • Marianne Suzanne de Wolff
  • Jan Wallander
  • May Britt Drugli
  • Child Adolesc Ment Health.2018 Nov;23(4):368-375. doi: 10.1111/camh.12257.Epub 2018-01-25.

スリランカにおける鎌状赤血球症：臨床的・分子的基盤と疾患の重症度に関する未解明の疑問

Sickle cell disease in Sri Lanka: clinical and molecular basis and the unanswered questions about disease severity.
  • Thamal Darshana
  • Dayananda Bandara
  • Upul Nawarathne
  • Udaya de Silva
  • Yasinta Costa
  • Kalavitigoda Pushpakumara
  • Sumithra Pathirage
  • Seuwandi Basnayake
  • Chamila Epa
  • Pradeepa Dilrukshi
  • Maheshaka Wijayawardena
  • Angela A Anthony
  • Rexan Rodrigo
  • Aresha Manamperi
  • Frances Smith
  • Angela Allen
  • Stephan Menzel
  • David Rees
  • Anuja Premawardhena
  • Orphanet J Rare Dis.2020 Jul;15(1):177. 10.1186/s13023-020-01458-w. doi: 10.1186/s13023-020-01458-w.Epub 2020-07-06.

進行性非扁平上皮非EGFR変異非小細胞肺癌に対する維持療法としてペメトレキセド対エルロチニブを投与された患者のQOLの無作為化第3相オープンラベル試験

Randomized phase 3 open label study of quality of life of patients on Pemetrexed versus Erlotinib as maintenance therapy for advanced non squamous non EGFR mutated non small cell lung cancer.
  • Vijay Patil
  • Amit Joshi
  • Vanita Noronha
  • Vivek Agarwala
  • Anuradha Chougule
  • Sadhana Kanan
  • Atanu Bhattacharjee
  • Arun Chandrasekharan
  • Nikhil Pande
  • Vijai Simha
  • Supriya Goud
  • Sucheta More
  • Rajiv Kumar
  • Abhishek Mahajan
  • Amit Janu
  • Nilendu Purandare
  • Kumar Prabhash
  • Oncotarget.2019 Oct;10(59):6297-6307. 27214. doi: 10.18632/oncotarget.27214.Epub 2019-10-29.

ニューヨーク市でのCOVID-19サージ時の心臓集中治療室と心臓集中治療医

The cardiac intensive care unit and the cardiac intensivist during the COVID-19 surge in New York City.
  • D Edmund Anstey
  • Raymond Givens
  • Kevin Clerkin
  • Justin Fried
  • Nellie Kalcheva
  • Deepa Kumaraiah
  • Amirali Masoumi
  • Daniel O'Connor
  • Gregg F Rosner
  • Lauren Wasson
  • Jeffrey Hammond
  • Ajay J Kirtane
  • Nir Uriel
  • Allan Schwartz
  • LeRoy E Rabbani
  • Marwah Abdalla
  • Am. Heart J..2020 Jul;227:74-81. S0002-8703(20)30198-8. doi: 10.1016/j.ahj.2020.06.018.Epub 2020-07-03.

湿地植物Alisma orientaleによるパーフルオロオクタン酸およびパーフルオロオクタンスルホン酸の取り込み機構、細胞内分布および取り込み過程（英文

Uptake mechanism, subcellular distribution, and uptake process of perfluorooctanoic acid and perfluorooctane sulfonic acid by wetland plant Alisma orientale.
  • Tuan-Tuan Wang
  • Guang-Guo Ying
  • Liang-Ying He
  • You-Sheng Liu
  • Jian-Liang Zhao
  • Sci. Total Environ..2020 Sep;733:139383. S0048-9697(20)32900-4. doi: 10.1016/j.scitotenv.2020.139383.Epub 2020-05-13.

聴覚障害を持つ思春期の生徒の学校関与に対するビデオガイド付き教育介入の効果。保健体育教育への示唆

Effect of video-guided educational intervention on school engagement of adolescent students with hearing impairment: Implications for health and physical education.
  • Uche D Asogwa
  • Theresa Onyema Ofoegbu
  • Chimaobi Samuel Ogbonna
  • Michael Eskay
  • Ngozi O Obiyo
  • Godfrey C Nji
  • Oliver Rotachukwu Ngwoke
  • Chiedu Eseadi
  • Christian Iheanacho Agboti
  • Chinedozie Uwakwe
  • Benedict C Eze
  • Medicine (Baltimore).2020 Jun;99(23):e20643. 00005792-202006050-00088. doi: 10.1097/MD.0000000000020643.

鼻と副鼻腔に影響を及ぼす抗好中球細胞質抗体関連血管炎における手術の役割。システマティックレビュー

The role of surgery in antineutrophil cytoplasmic antibody-associated vasculitides affecting the nose and sinuses: A systematic review.
  • Alfonso Luca Pendolino
  • Samit Unadkat
  • Henry Zhang
  • Monica Pendolino
  • Gerolamo Bianchi
  • Premjit S Randhawa
  • Peter J Andrews
  • SAGE Open Med.2020;8:2050312120936731. 10.1177_2050312120936731. doi: 10.1177/2050312120936731.Epub 2020-07-01.

光力学的抗菌化学療法（PACT）のためのBSAナノ粒子担持メチレンブルー。光力学的抗菌化学療法(PACT)用BSAナノ粒子担持メチレンブルーによる成長とバイオフィルム形成への影響

BSA nanoparticles loaded-methylene blue for Photodynamic Antimicrobial Chemotherapy (PACT): Effect on both growth and biofilm formation by .
  • Jéssica Aparecida Ribeiro Ambrósio
  • Bruna Cristina Dos Santos Pinto
  • Bruna Graziele Marques da Silva
  • Juliene Cristina da Silva Passos
  • Milton Beltrame Junior
  • Maricilia Silva Costa
  • Andreza Ribeiro Simioni
  • J Biomater Sci Polym Ed.2020 Jul;:1-14. doi: 10.1080/09205063.2020.1795461.Epub 2020-07-11.

外用アンホテリシンBナノエマルジョンの開発、特性評価、および抗リーシュマニア活性

Development, characterization, and anti-leishmanial activity of topical amphotericin B nanoemulsions.
  • Ana Paula Dos Santos Matos
  • Deise Cristina Drummond Xavier Paes Lopes
  • Maria Luíza Honório Peixoto
  • Veronica da Silva Cardoso
  • Alane Beatriz Vermelho
  • Ralph Santos-Oliveira
  • Alessandra Lifsitch Viçosa
  • Carla Holandino
  • Eduardo Ricci-Júnior
  • Drug Deliv Transl Res.2020 Jul;10.1007/s13346-020-00821-5. doi: 10.1007/s13346-020-00821-5.Epub 2020-07-16.

神経原性下部尿路機能障害患者におけるナフトピジルの有効性と安全性。8週間のアクティブ対照、層別無作為化、二重盲検、二重ダミー、並行群、非劣性、多施設共同デザイン

Efficacy and Safety of Naftopidil in Patients With Neurogenic Lower Urinary Tract Dysfunction: An 8-Week, Active-Controlled, Stratified-Randomized, Double-Blind, Double-Dummy, Parallel Group, Noninferiority, Multicenter Design.
  • Hyun Hwan Sung
  • Myung-Soo Choo
  • Joon Chul Kim
  • Jang Hwan Kim
  • Kyu-Sung Lee
  • Int Neurourol J.2020 Jun;24(2):163-171. inj.1938198.099. doi: 10.5213/inj.1938198.099.Epub 2020-06-30.

水耕栽培培地中のパーフルオロオクタンスルホン酸とパーフルオロオクタンスルホン酸の複合曝露によるレタス根の代謝制御（英文

Metabolic regulations in lettuce root under combined exposure to perfluorooctanoic acid and perfluorooctane sulfonate in hydroponic media.
  • Pengyang Li
  • Zhiyong Xiao
  • Jiang Sun
  • Xihui Oyang
  • Xiaocan Xie
  • Zhifang Li
  • Xiujun Tian
  • Jiuyi Li
  • Sci. Total Environ..2020 Jul;726:138382. S0048-9697(20)31895-7. doi: 10.1016/j.scitotenv.2020.138382.Epub 2020-04-14.

イラン・ケルマン州バグヒン地域の熱水性ヘマタイト-バライト-ガレナ鉱脈周辺の土壌における重金属の地球化学的・環境的ベースラインの評価

Assessing the geochemical and environmental baseline of heavy metals in soils around hydrothermal hematite-barite-galena veins in Baghin area, Kerman, Iran.
  • Arezoo Alizadeh-Kouskuie
  • Habibeh Atapour
  • Farah Rahmani
  • Environ Geochem Health.2020 Jul;10.1007/s10653-020-00660-w. doi: 10.1007/s10653-020-00660-w.Epub 2020-07-16.

ブラジルにおけるリターナブル20Lパックの製造期間に応じた天然ミネラルウォーターの微生物学的品質の評価

Assessment of the microbiological quality of natural mineral waters according to the manufacturing time of 20 L returnable packs in Brazil.
  • Isabelle da Silva Luz
  • Luiza Vasconcellos
  • Valéria de Mello Medeiros
  • Catia Aparecida Chaia Miranda
  • Carla de Oliveira Rosas
  • Márcia Maria Araújo Pimenta
  • Fernando César Ferreira
  • Célia Maria Carvalho Pereira Araújo Romão
  • Marcelo Luiz Lima Brandão
  • Marize Pereira Miagostovich
  • FEMS Microbiol. Lett..2020 Jul;fnaa120. doi: 10.1093/femsle/fnaa120.Epub 2020-07-17.

腎機能と全転帰に焦点を当てた一般集団および糖尿病患者における可溶性高度糖化最終産物受容体（sRAGE）の役割を明らかにする

The role of soluble receptor for advanced glycation end-products (sRAGE) in the general population and patients with diabetes mellitus with a focus on renal function and overall outcome.
  • Mieke Steenbeke
  • Sander De Bruyne
  • Marc De Buyzere
  • Bruno Lapauw
  • Reinhart Speeckaert
  • Mirko Petrovic
  • Joris R Delanghe
  • Marijn M Speeckaert
  • Crit Rev Clin Lab Sci.2020 Jul;:1-18. doi: 10.1080/10408363.2020.1791045.Epub 2020-07-15.

カリフォルニア州サンフランシスコの安定しない収容女性における過剰摂取リスクへの対応：複数の物質の潜在的なフェンタニル汚染の検討

Addressing overdose risk among unstably housed women in San Francisco, California: an examination of potential fentanyl contamination of multiple substances.
  • Meredith C Meacham
  • Kara L Lynch
  • Phillip O Coffin
  • Amanda Wade
  • Eliza Wheeler
  • Elise D Riley
  • Harm Reduct J.2020 Mar;17(1):17. 10.1186/s12954-020-00361-8. doi: 10.1186/s12954-020-00361-8.Epub 2020-03-10.

ホジキンリンパ腫患者におけるPolymerase Chain Reactionに基づく診断を活用した場合の肺炎の発生率、臨床症状、転帰

Incidence, clinical presentation, and outcomes of pneumonia when utilizing Polymerase Chain Reaction-based diagnosis in patients with Hodgkin lymphoma.
  • Jason N Barreto
  • Carrie A Thompson
  • Patrick M Wieruszewski
  • Amanda G Pawlenty
  • Kristin C Mara
  • Ashley L Potter
  • Pritish K Tosh
  • Andrew H Limper
  • Leuk. Lymphoma.2020 Jul;:1-8. doi: 10.1080/10428194.2020.1786561.Epub 2020-07-05.

チタンを陽極として用いた水系媒体からの六価クロムの電気化学的除去。チタンを陽極として用いた水系媒体からの六価クロムの電気化学的除去：六価クロムの間接的な電気化学的還元と三価クロムのin-situ析出を同時に行った

Electrochemical Cr(VI) removal from aqueous media using titanium as anode: Simultaneous indirect electrochemical reduction of Cr(VI) and in-situ precipitation of Cr(III).
  • Fubing Yao
  • Maocong Jia
  • Qi Yang
  • Kun Luo
  • Fei Chen
  • Yu Zhong
  • Li He
  • Zhoujie Pi
  • Kunjie Hou
  • Dongbo Wang
  • Xiaoming Li
  • Chemosphere.2020 Jul;260:127537. S0045-6535(20)31731-8. doi: 10.1016/j.chemosphere.2020.127537.Epub 2020-07-05.

前立腺癌に対するシクロオキシゲナーゼ-2阻害薬とI-ブラキセラピーの併用の生化学的コントロール。非盲検対照無作為化試験のポストホック解析

Biochemical control of the combination of cyclooxygenase-2 inhibitor and I-brachytherapy for prostate cancer: Post hoc analysis of an open-label controlled randomized trial.
  • Yasushi Nakai
  • Nobumichi Tanaka
  • Isao Asakawa
  • Satoshi Anai
  • Makito Miyake
  • Yosuke Morizawa
  • Shunta Hori
  • Takuya Owari
  • Tomomi Fujii
  • Chiho Ohbayashi
  • Kaori Yamaki
  • Masatoshi Hasegawa
  • Kiyohide Fujimoto
  • Int. J. Urol..2020 Jun;doi: 10.1111/iju.14294.Epub 2020-06-26.

α1アドレナリン受容体拮抗薬のシナプス後感度に対する効果の違い。ラットの腰仙骨脊髄からの実質性ゼラチノサ下層神経細胞のシナプス後電流抑制のためのスライスパッチクランプ法を使用しています

Differential Effects of Alpha 1-Adrenoceptor Antagonists on the Postsynaptic Sensitivity: Using Slice Patch-Clamp Technique for Inhibitory Postsynaptic Current in Substantia Gelatinosa Neurons From Lumbosacral Spinal Cord in Rats.
  • Daisuke Uta
  • Tsuyoshi Hattori
  • Megumu Yoshimura
  • Int Neurourol J.2020 Jun;24(2):127-134. inj.1938248.124. doi: 10.5213/inj.1938248.124.Epub 2020-06-30.

ストイキオメトリー制御されたMoxW1-xTe2ナノウィスカー。白金を含まない色素増感太陽電池のための新しい電極触媒

Stoichiometry-Controlled MoxW1-xTe2 Nanowhiskers: A Novel Electrocatalyst for Pt-free Dye-Sensitized Solar Cells.
  • Roshan Jesus Mathew
  • Chuan-Pei Lee
  • Chi-Ang Tseng
  • Pradyumna Kumar Chand
  • Yi-June Huang
  • Han-Ting Chen
  • Kuo-Chuan Ho
  • Aswin Kumar Anbalagan
  • Chih-Hao Lee
  • Yit-Tsong Chen
  • ACS Appl Mater Interfaces.2020 Jul;doi: 10.1021/acsami.0c07075.Epub 2020-07-13.

藻類の細胞外マトリックスには、カラギーナンと呼ばれる硫酸化ガラクトンが含まれていることがわかった

To gel or not to gel: differential expression of carrageenan-related genes between the gametophyte and tetasporophyte life cycle stages of the red alga Chondrus crispus.
  • Agnieszka P Lipinska
  • Jonas Collén
  • Stacy A Krueger-Hadfield
  • Theo Mora
  • Elizabeth Ficko-Blean
  • Sci Rep.2020 Jul;10(1):11498. 10.1038/s41598-020-67728-6. doi: 10.1038/s41598-020-67728-6.Epub 2020-07-13.

高齢化を成功させる礎としての成人のワクチン接種：帯状疱疹ワクチン接種の事例。欧州高齢化学際評議会（EICA）の専門家によるフォーカスグループ

Adult vaccination as the cornerstone of successful ageing: the case of herpes zoster vaccination. A European Interdisciplinary Council on Ageing (EICA) expert focus group.
  • Fiona Ecarnot
  • Roberto Bernabei
  • Giovanni Gabutti
  • Sandro Giuffrida
  • Jean-Pierre Michel
  • Giovanni Rezza
  • Stefania Maggi
  • Aging Clin Exp Res.2019 Mar;31(3):301-307. 10.1007/s40520-019-01154-1. doi: 10.1007/s40520-019-01154-1.Epub 2019-02-25.

腸管神経系が腸管バリア機能と微生物相に与える影響を明らかにするため、直腸介在性直腸介在性低カンジオン症の子豚モデルを用いて、産後の発育に及ぼす影響を検討した

A piglet model of iatrogenic rectosigmoid hypoganglionosis reveals the impact of the enteric nervous system on gut barrier function and microbiota postnatal development.
  • Alexis Pierre Arnaud
  • Juliette Hascoet
  • Pauline Berneau
  • Francis LeGouevec
  • Julien Georges
  • Gwenaelle Randuineau
  • Michèle Formal
  • Sébastien Henno
  • Gaelle Boudry
  • J. Pediatr. Surg..2020 Jun;S0022-3468(20)30438-3. doi: 10.1016/j.jpedsurg.2020.06.018.Epub 2020-06-20.

ホロコンデンシンの低温電子顕微鏡構造から、サブユニットのフリップフロップ機構が明らかになった

Cryo-EM structures of holo condensin reveal a subunit flip-flop mechanism.
  • Byung-Gil Lee
  • Fabian Merkel
  • Matteo Allegretti
  • Markus Hassler
  • Christopher Cawood
  • Léa Lecomte
  • Francis J O'Reilly
  • Ludwig R Sinn
  • Pilar Gutierrez-Escribano
  • Marc Kschonsak
  • Sol Bravo
  • Takanori Nakane
  • Juri Rappsilber
  • Luis Aragon
  • Martin Beck
  • Jan Löwe
  • Christian H Haering
  • Nat. Struct. Mol. Biol..2020 Jul;10.1038/s41594-020-0457-x. doi: 10.1038/s41594-020-0457-x.Epub 2020-07-13.

クローン性および抗原特異的応答は、卵巣癌における腫瘍浸潤T細胞の予後効果を形成する

Clonality and antigen-specific responses shape the prognostic effects of tumor-infiltrating T cells in ovarian cancer.
  • Takemasa Tsuji
  • Kevin H Eng
  • Junko Matsuzaki
  • Sebastiano Battaglia
  • J Brian Szender
  • Anthony Miliotto
  • Sacha Gnjatic
  • Wiam Bshara
  • Carl D Morrison
  • Shashikant Lele
  • Ryan O Emerson
  • Jianmin Wang
  • Song Liu
  • Harlan Robins
  • Amit A Lugade
  • Kunle Odunsi
  • Oncotarget.2020 Jul;11(27):2669-2683. 27666. doi: 10.18632/oncotarget.27666.Epub 2020-07-07.

アフラトキシンM1-ウシα-ラクトアルブミン複合体形成の分光学的研究と分子モデル化

Spectroscopic studies and molecular modelling of the aflatoxin M1-bovine α-lactalbumin complex formation.
  • Carlos Jiménez-Pérez
  • Salvador R Tello-Solís
  • Carlos Z Gómez-Castro
  • Sergio Alatorre-Santamaría
  • Lorena Gómez-Ruiz
  • Gabriela Rodríguez-Serrano
  • Julián Cruz-Borbolla
  • Mariano García-Garibay
  • Alma Cruz-Guerrero
  • J. Photochem. Photobiol. B, Biol..2020 Jul;209:111957. S1011-1344(20)30407-3. doi: 10.1016/j.jphotobiol.2020.111957.Epub 2020-07-10.

硫化工学で設計された CoO の強化されたペルオキシダーゼ模倣機能と静電凝集を組み合わせた新しいアルカリホスファターゼ活性センシング戦略

A novel alkaline phosphatase activity sensing strategy combining enhanced peroxidase-mimetic feature of sulfuration-engineered CoO with electrostatic aggregation.
  • Hongwei Song
  • Xiangheng Niu
  • Kun Ye
  • Linjie Wang
  • Yuhu Xu
  • Yinxian Peng
  • Anal Bioanal Chem.2020 Jul;10.1007/s00216-020-02815-1. doi: 10.1007/s00216-020-02815-1.Epub 2020-07-16.

脳血管疾患イメージング病変の有病率と不均一性

Prevalence and Heterogeneity of Cerebrovascular Disease Imaging Lesions.
  • Jonathan Graff-Radford
  • Jeremiah A Aakre
  • David S Knopman
  • Christopher G Schwarz
  • Kelly D Flemming
  • Alejandro A Rabinstein
  • Jeffrey L Gunter
  • Chadwick P Ward
  • Samantha M Zuk
  • A J Spychalla
  • Gregory M Preboske
  • Ronald C Petersen
  • Kejal Kantarci
  • John Huston
  • Clifford R Jack
  • Michelle M Mielke
  • Prashanthi Vemuri
  • Mayo Clin. Proc..2020 Jun;95(6):1195-1205. S0025-6196(20)30086-0. doi: 10.1016/j.mayocp.2020.01.028.

味覚受容体遺伝子多型とう蝕との関連

Association of taste receptor gene polymorphisms with dental caries.
  • Juliana Arid
  • Lívia Azeredo Alves Antunes
  • Luiza Foltran de Azevedo Koch
  • Silvane Silva Evangelista
  • Katia Regina Felizardo Vasconcelos
  • João Armando Brancher
  • Marilisa Carneiro Leão Gabardo
  • Ana Julia Milani
  • André Luiz Tannus Dutra
  • Leonardo Santos Antunes
  • Alexandre Rezende Vieira
  • Juliana Feltrin-Souza
  • Erika Calvano KÜchler
  • Braz Oral Res.2020;34:e055. S1806-83242020000100243. doi: 10.1590/1807-3107bor-2020.vol34.0055.Epub 2020-06-19.

マイコバクテリアのtRNA修飾を標的とした新しいクラスの阻害剤の断片的発見

Fragment-based discovery of a new class of inhibitors targeting mycobacterial tRNA modification.
  • Sherine E Thomas
  • Andrew J Whitehouse
  • Karen Brown
  • Sophie Burbaud
  • Juan M Belardinelli
  • Jasper Sangen
  • Ramanuj Lahiri
  • Mark Daben J Libardo
  • Pooja Gupta
  • Sony Malhotra
  • Helena I M Boshoff
  • Mary Jackson
  • Chris Abell
  • Anthony G Coyne
  • Tom L Blundell
  • Rodrigo Andres Floto
  • Vítor Mendes
  • Nucleic Acids Res..2020 Jun;gkaa539. doi: 10.1093/nar/gkaa539.Epub 2020-06-30.

セロトニン作動性およびGABA作動性経路の寄与を持つ有望なキノリン含有セレンの抗不安作用。マウスにおける不安に関連するパラメータの変調

The anxiolytic effect of a promising quinoline containing selenium with the contribution of the serotonergic and GABAergic pathways: Modulation of parameters associated with anxiety in mice.
  • Jaini J Paltian
  • Angélica S Dos Reis
  • Renata L de Oliveira
  • Caren A R da Fonseca
  • William B Domingues
  • Eduardo N Dellagostin
  • Vinícius F Campos
  • Roberta Kruger
  • Diego Alves
  • Cristiane Luchese
  • Ethel A Wilhelm
  • Behav. Brain Res..2020 Jul;393:112797. S0166-4328(20)30496-4. doi: 10.1016/j.bbr.2020.112797.Epub 2020-07-07.

バイオミメティックハイドロキシアパタイト配合歯磨き粉の毎日の使用と象牙質知覚過敏、歯の滑らかさ、歯のホワイトニング、歯肉出血、爽快感への主観的影響

Daily Application of a Toothpaste with Biomimetic Hydroxyapatite and Its Subjective Impact on Dentin Hypersensitivity, Tooth Smoothness, Tooth Whitening, Gum Bleeding, and Feeling of Freshness.
  • Sonja Steinert
  • Kai Zwanzig
  • Helga Doenges
  • Joern Kuchenbecker
  • Frederic Meyer
  • Joachim Enax
  • Biomimetics (Basel).2020 Apr;5(2). E17. doi: 10.3390/biomimetics5020017.Epub 2020-04-28.

LPS/TLR2免疫軸によって制御されるマイクロRNAは、急性レプトスピラ症の診断のためのボナイドバイオマーカーとして

MicroRNAs Regulated by the LPS/TLR2 Immune Axis as Bona Fide Biomarkers for Diagnosis of Acute Leptospirosis.
  • Charles Solomon Akino Mercy
  • Natarajaseenivasan Suriya Muthukumaran
  • Prema Velusamy
  • Palanisamy Bothammal
  • Krishnamoorthi Sumaiya
  • Perumal Saranya
  • Dianne Langford
  • Santhanam Shanmughapriya
  • Kalimuthusamy Natarajaseenivasan
  • mSphere.2020 Jul;5(4). e00409-20. doi: 10.1128/mSphere.00409-20.Epub 2020-07-15.

FGF15/19-TFEB制御ループが肝コレステロールと胆汁酸のホメオスタシスを制御していることが明らかになった

An FGF15/19-TFEB regulatory loop controls hepatic cholesterol and bile acid homeostasis.
  • Yifeng Wang
  • Sumedha Gunewardena
  • Feng Li
  • David J Matye
  • Cheng Chen
  • Xiaojuan Chao
  • Taeyoon Jung
  • Yuxia Zhang
  • Maciej Czerwiński
  • Hong-Min Ni
  • Wen-Xing Ding
  • Tiangang Li
  • Nat Commun.2020 Jul;11(1):3612. 10.1038/s41467-020-17363-6. doi: 10.1038/s41467-020-17363-6.Epub 2020-07-17.

RNAseq 解析により、NaCl ストレス下で栽培されたキャノーラ（L.）の選択的イオンの摂取量に差が生じる主要なイオントランスポーターの発現変化が明らかになった

RNAseq Analysis Reveals Altered Expression of Key Ion Transporters Causing Differential Uptake of Selective Ions in Canola ( L.) Grown under NaCl Stress.
  • Mobina Ulfat
  • Habib-Ur-Rehman Athar
  • Zaheerud-Din Khan
  • Hazem M Kalaji
  • Plants (Basel).2020 Jul;9(7). E891. doi: 10.3390/plants9070891.Epub 2020-07-14.

エチオピアにおけるPlasmodium vivaxの共蔓性のレベルが異なる環境下でのPlasmodium falciparum PfcrtおよびPfmdr1対立遺伝子の有病率

Prevalence of Plasmodium falciparum Pfcrt and Pfmdr1 alleles in settings with different levels of Plasmodium vivax co-endemicity in Ethiopia.
  • Elifaged Hailemeskel
  • Temesgen Menberu
  • Girma Shumie
  • Sinknesh Behaksra
  • Wakweya Chali
  • Migbaru Keffale
  • Mulualem Belachew
  • Getasew Shitaye
  • Hussien Mohammed
  • Daniel Abebe
  • Temesgen Ashine
  • Chris Drakeley
  • Hassen Mamo
  • Beyene Petros
  • Teun Bousema
  • Fitsum G Tadesse
  • Endalamaw Gadisa
  • Int J Parasitol Drugs Drug Resist.2019 12;11:8-12. S2211-3207(19)30065-X. doi: 10.1016/j.ijpddr.2019.09.002.Epub 2019-09-09.

テストステロンはアンドロゲンおよびエストロゲン受容体の活性化を介してin vitroで線維芽細胞増殖を増加させます

Testosterone Increases Fibroblast Proliferation in vitro Through Androgen and Estrogen Receptor Activation.
  • Luis Carlos Leal Santana
  • Luis Carlos Spolidorio
  • Jonleno Coutinho Paiva Pitombo
  • Fernanda Gonçalves Basso
  • Gabriel Guidio Guarenghi
  • Rodolfo Coelho Prates
  • João Paulo Steffens
  • J Int Acad Periodontol.2020 Jul;22(3):146-155. 22-3-2020-129. Epub 2020-07-01.

ミエロイド細胞におけるBmal1欠損は動脈硬化性病変の発生を抑制し、高脂血症マウスにおける腹部大動脈瘤形成を抑制する

Bmal1 Deletion in Myeloid Cells Attenuates Atherosclerotic Lesion Development and Restrains Abdominal Aortic Aneurysm Formation in Hyperlipidemic Mice.
  • Guangrui Yang
  • Jiayang Zhang
  • Tingting Jiang
  • James Monslow
  • Soon Yew Tang
  • Leslie Todd
  • Ellen Puré
  • Lihong Chen
  • Garret A FitzGerald
  • Arterioscler. Thromb. Vasc. Biol..2020 06;40(6):1523-1532. doi: 10.1161/ATVBAHA.120.314318.Epub 2020-04-23.

画像解析を用いた懸濁物質濃度の連続モニタリングと機械学習による固有の相関関係の導出

Continuous monitoring of suspended sediment concentrations using image analytics and deriving inherent correlations by machine learning.
  • Mohammad Ali Ghorbani
  • Rahman Khatibi
  • Vijay P Singh
  • Ercan Kahya
  • Heikki Ruskeepää
  • Mandeep Kaur Saggi
  • Bellie Sivakumar
  • Sungwon Kim
  • Farzin Salmasi
  • Mahsa Hasanpour Kashani
  • Saeed Samadianfard
  • Mahmood Shahabi
  • Rasoul Jani
  • Sci Rep.2020 May;10(1):8589. 10.1038/s41598-020-64707-9. doi: 10.1038/s41598-020-64707-9.Epub 2020-05-22.

可溶性ヒトプログラムされた細胞死タンパク質-1の産生：CD4+T細胞の細胞毒性と腫瘍細胞のアポトーシスのための天然のサポーター

Producing Soluble Human Programmed Cell Death Protein-1: A Natural Supporter for CD4+T Cell Cytotoxicity and Tumor Cells Apoptosis.
  • Samane Mohammadzadeh
  • Hossein Khanahmad
  • Nafiseh Esmaeil
  • Nahid Eskandari
  • Ilnaz Rahimmanesh
  • Abbas Rezaei
  • Alireza Andalib
  • Iran. J. Biotechnol..2019 Dec;17(4):e2104. IJB-17-4. doi: 10.30498/IJB.2019.85180.Epub 2019-12-01.

脱コロニー化ではなく疾患予防-多剤耐性菌をコロニー化した患者における糞便性微生物叢移植のモデル

Disease prevention not decolonization - a model for fecal microbiota transplantation in patients colonized with multidrug-resistant organisms.
  • Rohma Ghani
  • Benjamin H Mullish
  • Julie A K McDonald
  • Anan Ghazy
  • Horace R T Williams
  • Eimear T Brannigan
  • Siddharth Mookerjee
  • Giovanni Satta
  • Mark Gilchrist
  • Neill Duncan
  • Richard Corbett
  • Andrew J Innes
  • Jiří Pavlů
  • Mark R Thursz
  • Frances Davies
  • Julian R Marchesi
  • Clin. Infect. Dis..2020 Jul;ciaa948. doi: 10.1093/cid/ciaa948.Epub 2020-07-18.

Ni(II), Cu(II), Co(II)を用いた二次元MOFの効率的な酸素発生電極触媒としての性能.触媒性能とMOFの構造とレドックスカップリングのポテンシャルの合理化

2D- MOFs with Ni(II), Cu(II) and Co(II) as Efficient Oxygen Evolution Electrocatalysts: Rationalization of Catalytic Performance vs Structure of the MOFs and Potential of the Redox Couples.
  • Anindita Goswami
  • Debanjali Ghosh
  • Vladimir V Chernyshev
  • Avishek Dey
  • Debabrata Pradhan
  • Kumar Biradha
  • ACS Appl Mater Interfaces.2020 Jul;doi: 10.1021/acsami.0c07268.Epub 2020-07-07.

COVID-19患者の詳細な免疫プロファイリングにより、治療上の意味を持つ異なる免疫型が明らかになった

Deep immune profiling of COVID-19 patients reveals distinct immunotypes with therapeutic implications.
  • Divij Mathew
  • Josephine R Giles
  • Amy E Baxter
  • Derek A Oldridge
  • Allison R Greenplate
  • Jennifer E Wu
  • Cécile Alanio
  • Leticia Kuri-Cervantes
  • M Betina Pampena
  • Kurt D'Andrea
  • Sasikanth Manne
  • Zeyu Chen
  • Yinghui Jane Huang
  • John P Reilly
  • Ariel R Weisman
  • Caroline A G Ittner
  • Oliva Kuthuru
  • Jeanette Dougherty
  • Kito Nzingha
  • Nicholas Han
  • Justin Kim
  • Ajinkya Pattekar
  • Eileen C Goodwin
  • Elizabeth M Anderson
  • Madison E Weirick
  • Sigrid Gouma
  • Claudia P Arevalo
  • Marcus J Bolton
  • Fang Chen
  • Simon F Lacey
  • Holly Ramage
  • Sara Cherry
  • Scott E Hensley
  • Sokratis A Apostolidis
  • Alexander C Huang
  • Laura A Vella
  • Michael R Betts
  • Nuala J Meyer
  • E John Wherry
  • Science.2020 Jul;eabc8511. doi: 10.1126/science.abc8511.Epub 2020-07-15.

膵管腺癌における(プロ)レニン受容体に対するモノクローナル抗体の抗増殖効果

Antiproliferative effects of monoclonal antibodies against (pro)renin receptor in pancreatic ductal adenocarcinoma.
  • Asadur Rahman
  • Makoto Matsuyama
  • Akio Ebihara
  • Yuki Shibayama
  • Arif Ul Hasan
  • Hironori Nakagami
  • Fumiaki Suzuki
  • Jiao Sun
  • Tomoe Kobayashi
  • Hiroki Hayashi
  • Daisuke Nakano
  • Hideki Kobara
  • Tsutomu Masaki
  • Akira Nishiyama
  • Mol. Cancer Ther..2020 Jul;molcanther.0228.2019. doi: 10.1158/1535-7163.MCT-19-0228.Epub 2020-07-15.

自己免疫CD8 T細胞の炎症性プロファイルはLDHA活性の増加と好気性解糖に依存している

Proinflammatory profile of autoimmune CD8 T cells relies on increased LDHA activity and aerobic glycolysis.
  • M Margarida Souto-Carneiro
  • Karel D Klika
  • Mónica T Abreu
  • André P Meyer
  • Rainer Saffrich
  • Roger Sandhoff
  • Richard Jennemann
  • Franziska V Kraus
  • Lars-Oliver Tykocinski
  • Volker Eckstein
  • Lina Carvalho
  • Mark Kriegsmann
  • Thomas Giese
  • Hanns-Martin Lorenz
  • Rui A Carvalho
  • 2020 Jun;doi: 10.1002/art.41420.Epub 2020-06-30.

メキシコの高齢者におけるCOVID-19の重症度および致死率に対する構造的健康決定要因および併存疾患の不平等な影響。時系列的な加齢を超えた考察

Unequal impact of structural health determinants and comorbidity on COVID-19 severity and lethality in older Mexican adults: Considerations beyond chronological aging.
  • Omar Yaxmehen Bello-Chavolla
  • Armando González-Díaz
  • Neftali Eduardo Antonio-Villa
  • Carlos A Fermín-Martínez
  • Alejandro Márquez-Salinas
  • Arsenio Vargas-Vázquez
  • Jessica Paola Bahena-López
  • Carmen García-Peña
  • Carlos A Aguilar-Salinas
  • Luis Miguel Gutiérrez-Robledo
  • J. Gerontol. A Biol. Sci. Med. Sci..2020 Jun;glaa163. doi: 10.1093/gerona/glaa163.Epub 2020-06-29.

ビフィドバクテリウム・アドレセンティスとラクトバチルス・ラムノサスは、腸内細菌叢に依存する異なる経路の調節を通じて、高脂肪・高コレステロール食によって誘導される非アルコール性脂肪性肝疾患を緩和することが示された

Bifidobacterium adolescentis and Lactobacillus rhamnosus alleviate non-alcoholic fatty liver disease induced by a high-fat, high-cholesterol diet through modulation of different gut microbiota-dependent pathways.
  • Gang Wang
  • Ting Jiao
  • Yue Xu
  • Daozheng Li
  • Qian Si
  • Jianfeng Hao
  • Jianxin Zhao
  • Hao Zhang
  • Wei Chen
  • Food Funct.2020 Jun;doi: 10.1039/c9fo02905b.Epub 2020-06-23.

吸入損傷が疑われる成人患者における自由対制限的挿管基準の予測適用可能性-レトロスペクティブ・コホート研究

The predictive applicability of liberal versus restrictive intubation criteria in adult patients with suspected inhalation injury - a retrospective cohort study.
  • Minesh Chotalia
  • Christine Pirrone
  • Thomas Mangham
  • Barbara Torlinska
  • Randeep Mullhi
  • Kaye England
  • Tomasz Torlinski
  • J Burn Care Res.2020 Jun;iraa092. doi: 10.1093/jbcr/iraa092.Epub 2020-06-06.

イメージング質量分析法は、ラットモデルにおける肝性温熱虚血と再灌流中のジヒドロキシコリン酸のタウリン抱合体の変化を明らかにします

Imaging Mass Spectrometry Reveals the Changes in the Taurine Conjugates of Dihydroxycholanoic Acid During Hepatic Warm Ischemia and Reperfusion in a Rat Model.
  • Kengo Shibata
  • Takahiro Hayasaka
  • Satsuki Hashimoto
  • Kohei Umemoto
  • Takahisa Ishikawa
  • Sodai Sakamoto
  • Koichi Kato
  • Shingo Shimada
  • Norio Kawamura
  • Kenji Wakayama
  • Nozomi Kobayashi
  • Yuka Hama
  • Moto Fukai
  • Tsuyoshi Shimamura
  • Akinobu Taketomi
  • Transplant. Proc..2020 Jun;S0041-1345(19)31739-7. doi: 10.1016/j.transproceed.2020.01.169.Epub 2020-06-30.

鳥類および魚類におけるアリール炭化水素受容体の低活性アゴニストへの曝露による早期ライフステージ死亡率の予測。種を超えた定量的副作用経路のアプローチ

Predicting Early Life Stage Mortality in Birds and Fishes from Exposure to Low Potency Agonists of the Aryl Hydrocarbon Receptor: A Cross-species Quantitative Adverse Outcome Pathway Approach.
  • Jon A Doering
  • Justin Dubiel
  • Steve Wiseman
  • Environ. Toxicol. Chem..2020 Jul;doi: 10.1002/etc.4816.Epub 2020-07-10.

インドネシアにおけるwMel Wolbachiaの規模での放流を用いたデング熱の制御の費用対効果：モデリング研究

The cost-effectiveness of controlling dengue in Indonesia using wMel Wolbachia released at scale: a modelling study.
  • Oliver J Brady
  • Dinar D Kharisma
  • Nandyan N Wilastonegoro
  • Kathleen M O'Reilly
  • Emilie Hendrickx
  • Leonardo S Bastos
  • Laith Yakob
  • Donald S Shepard
  • BMC Med.2020 Jul;18(1):186. 10.1186/s12916-020-01638-2. doi: 10.1186/s12916-020-01638-2.Epub 2020-07-09.

市中肺炎で入院した小児および成人におけるパラインフルエンザウイルス1～3型感染

Parainfluenza Virus Types 1-3 Infections Among Children and Adults Hospitalized with Community-Acquired Pneumonia.
  • Leigh M Howard
  • Kathryn M Edwards
  • Yuwei Zhu
  • Derek J Williams
  • Wesley H Self
  • Seema Jain
  • Krow Ampofo
  • Andrew T Pavia
  • Sandra R Arnold
  • Jonathan A McCullers
  • Evan J Anderson
  • Richard G Wunderink
  • Carlos G Grijalva
  • Clin. Infect. Dis..2020 Jul;ciaa973. doi: 10.1093/cid/ciaa973.Epub 2020-07-18.

幹細胞多能性遺伝子Klf4とOct4は、末期の動脈硬化性病変の発症に重要な複雑なSMC表現型の変化を制御している

The Stem Cell Pluripotency Genes Klf4 and Oct4 Regulate Complex SMC Phenotypic Changes Critical in Late-Stage Atherosclerotic Lesion Pathogenesis.
  • Gabriel F Alencar
  • Katherine M Owsiany
  • Santosh K
  • Katyayani Sukhavasi
  • Giuseppe Mocci
  • Anh Nguyen
  • Corey M Williams
  • Sohel Shamsuzzaman
  • Michal Mokry
  • Christopher A Henderson
  • Ryan Haskins
  • Richard A Baylis
  • Aloke V Finn
  • Coleen A McNamara
  • Eli R Zunder
  • Vamsidhar Venkata
  • Gerard Pasterkamp
  • Johan Björkegren
  • Stefan Bekiranov
  • Gary K Owens
  • Circulation.2020 Jul;doi: 10.1161/CIRCULATIONAHA.120.046672.Epub 2020-07-17.

トランスフェモラル大動脈弁置換術または外科的大動脈弁置換術後の大動脈弁狭窄症患者における右室機能のメタアナリシス

Meta-analysis of right ventricular function in patients with aortic stenosis after transfemoral aortic valve replacement or surgical aortic valve replacement.
  • Yunshan Cao
  • Vikas Singh
  • Aqian Wang
  • Liyan Zhang
  • Tingting He
  • Hongling Su
  • Rong Wei
  • Yichao Duan
  • Kaiyu Jiang
  • Wenyu Wu
  • Yan Huang
  • Sammy Elmariah
  • Guanming Qi
  • Xin Su
  • Yan Zhang
  • Min Zhang
  • Ther Adv Chronic Dis.2020;11:2040622320933775. 10.1177_2040622320933775. doi: 10.1177/2040622320933775.Epub 2020-07-03.

細菌性アミロイドcurliのin vivo合成は、S. Typhimurium感染時の関節炎症に寄与する

In vivo synthesis of bacterial amyloid curli contributes to joint inflammation during S. Typhimurium infection.
  • Amanda L Miller
  • J Alex Pasternak
  • Nicole J Medeiros
  • Lauren K Nicastro
  • Sarah A Tursi
  • Elizabeth G Hansen
  • Ryan Krochak
  • Akosiererem S Sokaribo
  • Keith D MacKenzie
  • Melissa B Palmer
  • Dakoda J Herman
  • Nikole L Watson
  • Yi Zhang
  • Heather L Wilson
  • R Paul Wilson
  • Aaron P White
  • Çagla Tükel
  • PLoS Pathog..2020 Jul;16(7):e1008591. PPATHOGENS-D-20-00087. doi: 10.1371/journal.ppat.1008591.Epub 2020-07-09.

化学療法誘発性末梢神経障害に対する鍼治療の有効性。A pilot, Randomized, Assessor-Blinded, Controlled Trial

Effectiveness of Acupuncture Treatment on Chemotherapy-Induced Peripheral Neuropathy: A Pilot, Randomized, Assessor-Blinded, Controlled Trial.
  • Somayeh Iravani
  • Amir Hooman Kazemi Motlagh
  • Seyede Zahra Emami Razavi
  • Farhad Shahi
  • Jing Wang
  • Li Hou
  • Wenjun Sun
  • Mohammad Reza Afshari Fard
  • Mahdi Aghili
  • Mehrdad Karimi
  • Hossein Rezaeizadeh
  • Baixiao Zhao
  • Pain Res Manag.2020;2020:2504674. doi: 10.1155/2020/2504674.Epub 2020-06-29.

大腸癌細胞におけるプログラムされた死のリガンド2（PD-L2）の発現を増加させるが、4-1BBリガンドの発現は増加させない

Increasing the expression of programmed death ligand 2 (PD-L2) but not 4-1BB ligand in colorectal cancer cells.
  • Parastoo Shakerin
  • Bijan Sedighi Moghadam
  • Kaveh Baghaei
  • Zahra Safaei Naraghi
  • Kambiz Kamyab Hesari
  • Hamid Asadzadeh Aghdaei
  • Raheleh Shokouhi Shoormasti
  • Mohammad Sadegh Fazeli
  • Maryam Nourizadeh
  • Mol. Biol. Rep..2020 Jul;10.1007/s11033-020-05289-7. doi: 10.1007/s11033-020-05289-7.Epub 2020-07-13.

口腔液中の17種類の乱用薬物の定量のための新しいLC-MS/MS確認法と実試料への適用

A new LC-MS/MS confirmation method for the determination of 17 drugs of abuse in oral fluid and its application to real samples.
  • Elisa Bassotti
  • Giuseppe Maria Merone
  • Annachiara D'Urso
  • Fabio Savini
  • Marcello Locatelli
  • Angela Tartaglia
  • Paolo Dossetto
  • Cristian D'Ovidio
  • Ugo de Grazia
  • Forensic Sci. Int..2020 Jul;312:110330. S0379-0738(20)30192-4. doi: 10.1016/j.forsciint.2020.110330.Epub 2020-05-12.

酸化ストレス、損傷と不十分な抗酸化防御が強化され、水不足ストレスと熱ストレスの組み合わせでの不十分な回復に向けて貢献している（Bathua）のいずれかのストレスだけではなく、どちらかのストレスに比べて

Enhanced oxidative stress, damage and inadequate antioxidant defense contributes towards insufficient recovery in water deficit stress and heat stress combination compared to either stresses alone in (Bathua).
  • Vimal Kumar Semwal
  • Renu Khanna-Chopra
  • Physiol Mol Biol Plants.2020 Jul;26(7):1331-1339. 821. doi: 10.1007/s12298-020-00821-2.Epub 2020-06-10.

単一粒子低温電子顕微鏡によるGPCRシグナル伝達複合体の構造研究のための"プラグアンドプレイ"フィデューシャルマークの開発

Development of "Plug and Play" Fiducial Marks for Structural Studies of GPCR Signaling Complexes by Single-Particle Cryo-EM.
  • Przemyslaw Dutka
  • Somnath Mukherjee
  • Xiang Gao
  • Yanyong Kang
  • Parker W de Waal
  • Lei Wang
  • Youwen Zhuang
  • Karsten Melcher
  • Cheng Zhang
  • H Eric Xu
  • Anthony A Kossiakoff
  • Structure.2019 12;27(12):1862-1874.e7. S0969-2126(19)30345-4. doi: 10.1016/j.str.2019.10.004.Epub 2019-10-25.

感染前の腸内細菌叢の組成がニワトリのサルモネラのスーパー型およびローシェダー型の表現型を決定する

Gut microbiota composition before infection determines the Salmonella super- and low-shedder phenotypes in chicken.
  • Florent Kempf
  • Pierrette Menanteau
  • Ivan Rychlik
  • Tereza Kubasová
  • Jérôme Trotereau
  • Isabelle Virlogeux-Payant
  • Samantha Schaeffer
  • Catherine Schouler
  • Rosanna Drumo
  • Edouard Guitton
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  • Microb Biotechnol.2020 Jul;doi: 10.1111/1751-7915.13621.Epub 2020-07-08.

血小板活性化と血小板依存性単球凝集体形成は，重症COVID-19患者における組織因子発現の引き金となる．

Platelet activation and platelet-monocyte aggregates formation trigger tissue factor expression in severe COVID-19 patients.
  • Eugenio Damaceno Hottz
  • Isaclaudia G Azevedo-Quintanilha
  • Lohanna Palhinha
  • Lívia Teixeira
  • Ester A Barreto
  • Camila R R Pão
  • Cássia Righy
  • Sérgio Franco
  • Thiago Moreno L Souza
  • Pedro Kurtz
  • Fernando Augusto Bozza
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  • Blood.2020 Jul;blood.2020007252. doi: 10.1182/blood.2020007252.Epub 2020-07-17.

可逆的かつ選択的なDNMT1阻害剤による胎児ヘモグロビンのin vitroおよびin vivo誘導

In vitro and in vivo induction of fetal hemoglobin with a reversible and selective DNMT1 inhibitor.
  • Aidan G Gilmartin
  • Arthur Groy
  • Elizabeth R Gore
  • Charity Atkins
  • Edward R Long
  • Monica N Montoute
  • Zining Wu
  • Wendy Halsey
  • Dean E McNulty
  • Daniela Ennulat
  • Lourdes Rueda
  • Melissa Pappalardi
  • Ryan G Kruger
  • Michael T McCabe
  • Ali Raoof
  • Roger Butlin
  • Alexandra Stowell
  • Mark Cockerill
  • Ian Waddell
  • Donald Ogilvie
  • Juan Luengo
  • Allan Jordan
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  • Haematologica.2020 Jun;haematol.2020.248658. doi: 10.3324/haematol.2020.248658.Epub 2020-06-25.

ブラジル北東部の4つの環境的に異なる地域でのアオイサギ（Diptera: Culicidae）の排卵動態に及ぼす気象変数の影響

The influence of meteorological variables on the oviposition dynamics of Aedes aegypti (Diptera: Culicidae) in four environmentally distinct areas in northeast Brazil.
  • Isabella Cristina da Silva Santos
  • Cynthia Braga
  • Wayner Vieira de Souza
  • André Luiz Sá de Oliveira
  • Lêda Narcisa Regis
  • Mem. Inst. Oswaldo Cruz.2020;115:e200046. S0074-02762020000100326. doi: 10.1590/0074-02760200046.Epub 2020-07-10.

開発中の巨大都市の影響を受けた熱帯河川河口域の堆積物の堆積物学的・地球化学的データ

Sedimentological and geochemical data in bed sediments from a tropical river-estuary system impacted by a developing megacity, Ho Chi Minh City - Vietnam.
  • David Noncent
  • Emilie Strady
  • Julien Némery
  • Nguyen Thanh-Nho
  • Hervé Denis
  • Brice Mourier
  • Marc Babut
  • Truong An Nguyen
  • Thi Ngoc Tuyet Nguyen
  • Cyril Marchand
  • Marc Desmet
  • Anh Tu Tran
  • Joanne Aimé
  • Nicolas Gratiot
  • Quoc Tuc Dinh
  • Phuoc Dan Nguyen
  • Data Brief.2020 Aug;31:105938. S2352-3409(20)30832-5. doi: 10.1016/j.dib.2020.105938.Epub 2020-06-27.

デングウイルスおよびノロウイルスのRNA依存性RNAポリメラーゼにおける新規アロステリック部位を標的とした広汎なウイルス阻害剤の同定

Identification of a Broad-Spectrum Viral Inhibitor Targeting a Novel Allosteric Site in the RNA-Dependent RNA Polymerases of Dengue Virus and Norovirus.
  • Dongrong Yi
  • Quanjie Li
  • Lili Pang
  • Yujia Wang
  • Yongxin Zhang
  • Zhaojun Duan
  • Chen Liang
  • Shan Cen
  • Front Microbiol.2020;11:1440. doi: 10.3389/fmicb.2020.01440.Epub 2020-06-25.

ベルベリンはLKB1-AMPK-TORC2シグナル伝達経路を介してストレプトゾトシン誘発糖尿病ラットの骨格筋および脂肪組織におけるグルコネオジェネシスを阻害する

Berberine Inhibits Gluconeogenesis in Skeletal Muscles and Adipose Tissues in Streptozotocin-induced Diabetic Rats via LKB1-AMPK-TORC2 Signaling Pathway.
  • Xiao-Hu Xu
  • Qian Hu
  • Li-Shan Zhou
  • Li-Jun Xu
  • Xin Zou
  • Fu-Er Lu
  • Ping Yi
  • Curr Med Sci.2020 Jun;40(3):530-538. 10.1007/s11596-020-2210-4. doi: 10.1007/s11596-020-2210-4.Epub 2020-07-17.

試験プロトコル：リタイアメントビレッジの高齢者。有害な転帰を回避するように設計された多職種による発明の調査および無作為化試験

Study protocol: older people in retirement villages. A survey and randomised trial of a multi-disciplinary invention designed to avoid adverse outcomes.
  • K Peri
  • J B Broad
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  • M Boyd
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  • BMC Geriatr.2020 Jul;20(1):247. 10.1186/s12877-020-01640-6. doi: 10.1186/s12877-020-01640-6.Epub 2020-07-17.

前例のないスイッチング耐久性により、スピンクロスオーバー膜を用いた高分解能表面温度マッピングが可能となる

Unprecedented switching endurance affords for high-resolution surface temperature mapping using a spin-crossover film.
  • Karl Ridier
  • Alin-Ciprian Bas
  • Yuteng Zhang
  • Lucie Routaboul
  • Lionel Salmon
  • Gábor Molnár
  • Christian Bergaud
  • Azzedine Bousseksou
  • Nat Commun.2020 Jul;11(1):3611. 10.1038/s41467-020-17362-7. doi: 10.1038/s41467-020-17362-7.Epub 2020-07-17.

骨肉腫患者における術前化学療法効果の予測のための三相造影MRI：(99m)Tc-MIBIシンチグラフィとの比較

Triple-phase contrast-enhanced MRI for the prediction of preoperative chemotherapeutic effect in patients with osteosarcoma: comparison with (99m)Tc-MIBI scintigraphy.
  • Hiroshi Wakabayashi
  • Junko Saito
  • Junichi Taki
  • Nanako Hashimoto
  • Hiroyuki Tsuchiya
  • Toshifumi Gabata
  • Seigo Kinuya
  • Skeletal Radiol..2016 Jan;45(1):87-95. 10.1007/s00256-015-2250-1. doi: 10.1007/s00256-015-2250-1.Epub 2015-09-18.

うつ病のためのインターネットを利用した混合型心理療法へのプライマリケア患者の紹介の障壁と促進要因。一般開業医の見解の混合法研究

Barriers and facilitators for referrals of primary care patients to blended internet-based psychotherapy for depression: A mixed methods study of general practitioners' views.
  • Ingrid Titzler
  • Matthias Berking
  • Sandra Schlicker
  • Heleen Riper
  • David Daniel Ebert
  • JMIR Ment Health.2020 Jul;doi: 10.2196/18642.Epub 2020-07-09.

癌細胞におけるプロテアソームターンオーバー促進によるプロテアソーム障害下での細胞保護を促進するO-GlcNAcylationの増強

Enhanced O-GlcNAcylation Mediates Cytoprotection under Proteasome Impairment by Promoting Proteasome Turnover in Cancer Cells.
  • Eiichi Hashimoto
  • Shota Okuno
  • Shoshiro Hirayama
  • Yoshiyuki Arata
  • Tsuyoshi Goto
  • Hidetaka Kosako
  • Jun Hamazaki
  • Shigeo Murata
  • iScience.2020 Jun;23(7):101299. S2589-0042(20)30486-7. doi: 10.1016/j.isci.2020.101299.Epub 2020-06-24.

ウガンダのコレラが発生しやすい地域の表流水源（湖、河川、灌漑用水路、池）と湧水からの飲料水と生活用水の水質：重要な物理化学的パラメータの分析

The quality of drinking and domestic water from the surface water sources (lakes, rivers, irrigation canals and ponds) and springs in cholera prone communities of Uganda: an analysis of vital physicochemical parameters.
  • Godfrey Bwire
  • David A Sack
  • Atek Kagirita
  • Tonny Obala
  • Amanda K Debes
  • Malathi Ram
  • Henry Komakech
  • Christine Marie George
  • Christopher Garimoi Orach
  • BMC Public Health.2020 Jul;20(1):1128. 10.1186/s12889-020-09186-3. doi: 10.1186/s12889-020-09186-3.Epub 2020-07-17.

また、オプランティア・ミルパ・アルタ由来の多糖類は、酸化ストレスを低減し、Nrf2発現をアップレギュレートすることにより、アルロキサン誘発性のINS-1細胞のアポトーシスを緩和することが明らかになった

Polysaccharides from Opuntia milpa alta alleviate alloxan-induced INS-1 cells apoptosis via reducing oxidative stress and upregulating Nrf2 expression.
  • Weiling Li
  • Kuan Lin
  • Mei Zhou
  • Qi Xiong
  • Chaoying Li
  • Qin Ru
  • Nutr Res.2020 May;77:108-118. S0271-5317(19)30583-4. doi: 10.1016/j.nutres.2020.02.004.Epub 2020-02-06.

4-{2,2-ジクロロ-1-()-(4-フルオロ-フェニル)ジアセン-イルテン-イル},-ジメチルアニリンの結晶構造とヒルシュフェルト表面解析

Crystal structure and Hirshfeld surface analysis of 4-{2,2-di-chloro-1-[()-(4-fluoro-phen-yl)diazen-yl]ethen-yl}-,-di-methyl-aniline.
  • Kadriye Özkaraca
  • Mehmet Akkurt
  • Namiq Q Shikhaliyev
  • Ulviyya F Askerova
  • Gulnar T Suleymanova
  • Irada M Shikhaliyeva
  • Ajaya Bhattarai
  • Acta Crystallogr E Crystallogr Commun.2020 Jun;76(Pt 6):811-815. vm2232. doi: 10.1107/S2056989020006106.Epub 2020-05-06.

脊椎動物学的研究: 広範囲にわたる遺伝子ツリーの不一致とプラスチッド遺伝子の進化速度不均一性との関連

Plastome phylogenomic study of Gentianeae (Gentianaceae): widespread gene tree discordance and its association with evolutionary rate heterogeneity of plastid genes.
  • Xu Zhang
  • Yanxia Sun
  • Jacob B Landis
  • Zhenyu Lv
  • Jun Shen
  • Huajie Zhang
  • Nan Lin
  • Lijuan Li
  • Jiao Sun
  • Tao Deng
  • Hang Sun
  • Hengchang Wang
  • BMC Plant Biol..2020 Jul;20(1):340. 10.1186/s12870-020-02518-w. doi: 10.1186/s12870-020-02518-w.Epub 2020-07-17.

ノルエピネフリントランスポーターを標的としたTcTcTc(CO)(HO)シンセソンを介して調製したImIBGのTcアナログの合成と評価

Synthesis and evaluation of Tc-analogues of [I]mIBG prepared via [Tc][Tc(CO)(HO)] synthon for targeting norepinephrine transporter.
  • Soumen Das
  • Navin Sakhare
  • Anupam Mathur
  • Madhava B Mallia
  • Shubhangi Mirapurkar
  • M Sheela
  • H D Sarma
  • S S Sachdev
  • Ashutosh Dash
  • Nucl. Med. Biol..2019 Jan - Feb;68-69:49-57. S0969-8051(18)30249-X. doi: 10.1016/j.nucmedbio.2019.01.001.Epub 2019-01-18.

エンパグリフロジンで治療された2型糖尿病患者における多因子性の重症高血糖性糖尿病性ケトアシドーシス：症例報告と文献レビュー

Severe euglycemic diabetic ketoacidosis of multifactorial etiology in a type 2 diabetic patient treated with empagliflozin: case report and literature review.
  • Erasmia Sampani
  • Pantelis Sarafidis
  • Chrysostomos Dimitriadis
  • Efstratios Kasimatis
  • Dimitra Daikidou
  • Konstantinos Bantis
  • Alexios Papanikolaou
  • Aikaterini Papagianni
  • BMC Nephrol.2020 Jul;21(1):276. 10.1186/s12882-020-01930-6. doi: 10.1186/s12882-020-01930-6.Epub 2020-07-15.

母乳で育てられた早産児の気管支肺異形成フリー生存率に母親のドコサヘキサエン酸のサプリメントの効果。無作為化臨床試験

Effect of Maternal Docosahexaenoic Acid Supplementation on Bronchopulmonary Dysplasia-Free Survival in Breastfed Preterm Infants: A Randomized Clinical Trial.
  • Isabelle Marc
  • Bruno Piedboeuf
  • Thierry Lacaze-Masmonteil
  • William Fraser
  • Benoît Mâsse
  • Ibrahim Mohamed
  • Mosarrat Qureshi
  • Jehier Afifi
  • Brigitte Lemyre
  • Georges Caouette
  • Julie Bartholomew
  • Anne Monique Nuyt
  • Pierre Julien
  • Anne Synnes
  • Michel Lucas
  • Thérèse Perreault
  • Lannae Strueby
  • Zenon Cieslak
  • Kamran Yusuf
  • Gustavo Pelligra
  • Edith Massé
  • Bodil Larsen
  • Cecilia de Cabo
  • Chelsea Ruth
  • Faiza Khurshid
  • Pascal M Lavoie
  • JAMA.2020 07;324(2):157-167. 2768134. doi: 10.1001/jama.2020.8896.

潜在的なフレーバー培養物。Lactobacillus harbinensis M1は、2,3-ブタンジオンとアセトインの高産生により、発酵豆乳のオルガノレプティックな品質を向上させる

A potential flavor culture: Lactobacillus harbinensis M1 improves the organoleptic quality of fermented soymilk by high production of 2,3-butanedione and acetoin.
  • Yin Zheng
  • Yongtao Fei
  • Yue Yang
  • Zekun Jin
  • Baoning Yu
  • Li Li
  • Food Microbiol..2020 Oct;91:103540. S0740-0020(20)30129-5. doi: 10.1016/j.fm.2020.103540.Epub 2020-05-03.

個別化された治療予測は、無作為化試験において、集団平均的なアプローチと比較して転帰を改善することができるか？大うつ病の急性期治療の実用的メガトリアールにおける多変量予測モデルの開発と検証

Can personalized treatment prediction improve the outcomes, compared with the group average approach, in a randomized trial? Developing and validating a multivariable prediction model in a pragmatic megatrial of acute treatment for major depression.
  • Toshi A Furukawa
  • Thomas P A Debray
  • Tatsuo Akechi
  • Mitsuhiko Yamada
  • Tadashi Kato
  • Michael Seo
  • Orestis Efthimiou
  • J Affect Disord.2020 Sep;274:690-697. S0165-0327(20)30097-5. doi: 10.1016/j.jad.2020.05.141.Epub 2020-05-30.

ナノメディシンと脂質ベースの薬物送達システムにおける残留溶媒：プロセスをよりよく理解するためのケーススタディ

Residual Solvents in Nanomedicine and Lipid-Based Drug Delivery Systems: a Case Study to Better Understand Processes.
  • Amrita Dikpati
  • Farzad Mohammadi
  • Karine Greffard
  • Caroline Quéant
  • Philippe Arnaud
  • Guillaume Bastiat
  • Iwona Rudkowska
  • Nicolas Bertrand
  • Pharm. Res..2020 Jul;37(8):149. 10.1007/s11095-020-02877-x. doi: 10.1007/s11095-020-02877-x.Epub 2020-07-17.

イブプロフェンではなくメタミゾールはセルトラリンの血漿中濃度を低下させる - 疼痛とうつ病・不安障害の同時治療への示唆

Metamizole but not Ibuprofen reduces the plasma concentration of sertraline - Implications for the concurrent treatment of pain and depression/anxiety disorders.
  • Arnim Johannes Gaebler
  • Georgios Schoretsanitis
  • Nagia Ben Omar
  • Ekkehard Haen
  • Katharina Endres
  • Christoph Hiemke
  • Michael Paulzen
  • Br J Clin Pharmacol.2020 Jul;doi: 10.1111/bcp.14471.Epub 2020-07-11.

メトホルミンの同定と妥当性の検証 トール様受容体経路を標的とすることでPM誘発マクロファージの細胞毒性を防御する

Identification and validation of metformin protects against PM-induced macrophages cytotoxicity by targeting toll like receptor pathway.
  • Yanfeng Shi
  • Josevata Werelagi Batibawa
  • Modibo Maiga
  • Baiyang Sun
  • Yang Li
  • Junchao Duan
  • Zhiwei Sun
  • Chemosphere.2020 Jul;251:126526. S0045-6535(20)30719-0. doi: 10.1016/j.chemosphere.2020.126526.Epub 2020-03-27.

高リスクの難治性神経芽腫に対するI-metaiodobenzylguanidine（I-mIBG）とtopotecanによる線量評価に基づく高活性療法

Dosimetry-based high-activity therapy with I-metaiodobenzylguanidine (I-mIBG) and topotecan for the treatment of high-risk refractory neuroblastoma.
  • Jose Genolla
  • Trinidad Rodriguez
  • Pablo Minguez
  • Ricardo Lopez-Almaraz
  • Veronica Llorens
  • Aizpea Echebarria
  • Eur. J. Nucl. Med. Mol. Imaging.2019 Jul;46(7):1567-1575. 10.1007/s00259-019-04291-x. doi: 10.1007/s00259-019-04291-x.Epub 2019-03-05.

シンバスタチン負荷高分子ミセルは、進行性慢性肝疾患の前臨床モデルにおいて、従来のスタチンよりも有効性が高く、毒性が低いことが示された

Simvastatin-loaded polymeric micelles are more effective and less toxic than conventional statins in a pre-clinical model of advanced chronic liver disease.
  • Diana Hide
  • Mar Gil
  • Fernanda Andrade
  • Diana Rafael
  • Imma Raurell
  • Miren Bravo
  • Aurora Barberá
  • Jordi Gracia-Sancho
  • Víctor Vargas
  • Salvador Augustin
  • Joan Genescà
  • Simo Schwartz
  • Maria Martell
  • Nanomedicine.2020 Jul;:102267. S1549-9634(20)30121-0. doi: 10.1016/j.nano.2020.102267.Epub 2020-07-15.

多糖類を豊富に含むヒドロゲル製剤と光生物学的調節を組み合わせることで、マウスの皮膚における紫外線誘発性光損傷を修復します

Polysaccharide-rich hydrogel formulation combined with photobiomodulation repairs UV-induced photodamage in mice skin.
  • Lia Mara Grosso Neves
  • Nivaldo Antonio Parizotto
  • Carla Roberta Tim
  • Elaine Medeiros Floriano
  • Renata F Vianna Lopez
  • Tiago Venâncio
  • João Batista Fernandes
  • Marcia Regina Cominetti
  • Wound Repair Regen.2020 Jun;doi: 10.1111/wrr.12826.Epub 2020-06-26.

スイカにおけるキュウリグリーンモットルモザイクウイルス感染に対応した長鎖ノンコーディングRNAと環状RNAのゲノムワイドな同定により、ceRNAネットワークが明らかになった

Genome-wide identification of long non-coding RNAs and circular RNAs reveal their ceRNA networks in response to cucumber green mottle mosaic virus infection in watermelon.
  • Yuyan Sun
  • Huiqing Zhang
  • Min Fan
  • Yanjun He
  • Pingan Guo
  • Arch. Virol..2020 May;165(5):1177-1190. 10.1007/s00705-020-04589-4. doi: 10.1007/s00705-020-04589-4.Epub 2020-03-30.

COVID-19パンデミック初期における泌尿器科における外科的・腫瘍学的臨床実践の世界的変化

Global change of surgical and oncological clinical practice in urology during early COVID-19 pandemic.
  • Robert Dotzauer
  • Katharina Böhm
  • Maximilian Peter Brandt
  • Peter Sparwasser
  • Maximilian Haack
  • Sebastian Karl Frees
  • Mohamed Mostafa Kamal
  • René Mager
  • Wolfgang Jäger
  • Thomas Höfner
  • Igor Tsaur
  • Axel Haferkamp
  • Hendrik Borgmann
  • World J Urol.2020 Jul;10.1007/s00345-020-03333-6. doi: 10.1007/s00345-020-03333-6.Epub 2020-07-04.

院内感染性とフルオロキノロン系抗菌薬，テトラサイクリン系抗菌薬，トリメトプリム-スルファメトキサゾール系抗菌薬への感受性が明らかになった

Comparative genomics and antimicrobial resistance profiling of isolates reveals nosocomial transmission and susceptibility to fluoroquinolones, tetracyclines and trimethoprim-sulfamethoxazole.
  • Delaney Burnard
  • Letitia Gore
  • Andrew Henderson
  • Ama Ranasinghe
  • Haakon Bergh
  • Kyra Cottrell
  • Derek S Sarovich
  • Erin P Price
  • David L Paterson
  • Patrick N A Harris
  • J. Clin. Microbiol..2020 Jun;JCM.00730-20. doi: 10.1128/JCM.00730-20.Epub 2020-06-24.

出版社の訂正。発達段階に特異的な分布とMblk-1、ミツバチの脳内でのエクシステロイドシグナル伝達に関与する転写因子のリン酸化

Publisher Correction: Developmental stage-specific distribution and phosphorylation of Mblk-1, a transcription factor involved in ecdysteroid-signaling in the honey bee brain.
  • Hitomi Kumagai
  • Takekazu Kunieda
  • Korefumi Nakamura
  • Yasuhiro Matsumura
  • Manami Namiki
  • Hiroki Kohno
  • Takeo Kubo
  • Sci Rep.2020 Jul;10(1):11577. 10.1038/s41598-020-68540-y. doi: 10.1038/s41598-020-68540-y.Epub 2020-07-09.

ユーラシアの大草原を越えた137の古代ヒトゲノム

137 ancient human genomes from across the Eurasian steppes.
  • Peter de Barros Damgaard
  • Nina Marchi
  • Simon Rasmussen
  • Michaël Peyrot
  • Gabriel Renaud
  • Thorfinn Korneliussen
  • J Víctor Moreno-Mayar
  • Mikkel Winther Pedersen
  • Amy Goldberg
  • Emma Usmanova
  • Nurbol Baimukhanov
  • Valeriy Loman
  • Lotte Hedeager
  • Anders Gorm Pedersen
  • Kasper Nielsen
  • Gennady Afanasiev
  • Kunbolot Akmatov
  • Almaz Aldashev
  • Ashyk Alpaslan
  • Gabit Baimbetov
  • Vladimir I Bazaliiskii
  • Arman Beisenov
  • Bazartseren Boldbaatar
  • Bazartseren Boldgiv
  • Choduraa Dorzhu
  • Sturla Ellingvag
  • Diimaajav Erdenebaatar
  • Rana Dajani
  • Evgeniy Dmitriev
  • Valeriy Evdokimov
  • Karin M Frei
  • Andrey Gromov
  • Alexander Goryachev
  • Hakon Hakonarson
  • Tatyana Hegay
  • Zaruhi Khachatryan
  • Ruslan Khaskhanov
  • Egor Kitov
  • Alina Kolbina
  • Tabaldiev Kubatbek
  • Alexey Kukushkin
  • Igor Kukushkin
  • Nina Lau
  • Ashot Margaryan
  • Inga Merkyte
  • Ilya V Mertz
  • Viktor K Mertz
  • Enkhbayar Mijiddorj
  • Vyacheslav Moiyesev
  • Gulmira Mukhtarova
  • Bekmukhanbet Nurmukhanbetov
  • Z Orozbekova
  • Irina Panyushkina
  • Karol Pieta
  • Václav Smrčka
  • Irina Shevnina
  • Andrey Logvin
  • Karl-Göran Sjögren
  • Tereza Štolcová
  • Angela M Taravella
  • Kadicha Tashbaeva
  • Alexander Tkachev
  • Turaly Tulegenov
  • Dmitriy Voyakin
  • Levon Yepiskoposyan
  • Sainbileg Undrakhbold
  • Victor Varfolomeev
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複製適合性小胞性口内炎ウイルスワクチンベクターは SARS-CoV-2 が媒介する病原体から保護します

Replication-competent vesicular stomatitis virus vaccine vector protects against SARS-CoV-2-mediated pathogenesis.
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原発運動野および皮質脊髄路の近くに位置する高悪性度グリオーマの放射線治療計画へのBOLD-fMRIおよびDTIの統合

Integration of BOLD-fMRI and DTI into radiation treatment planning for high-grade gliomas located near the primary motor cortexes and corticospinal tracts.
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Pre-initiation and elongation structures of full-length La Crosse virus polymerase reveal functionally important conformational changes.
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また、p62/SQSTM1 の分解阻害と転写活性化による蓄積は、NF-κB 活性化を介したシリカナノ粒子誘起気道炎症に重要な役割を果たしていることが示唆された

p62/SQSTM1 accumulation due to degradation inhibition and transcriptional activation plays a critical role in silica nanoparticle-induced airway inflammation via NF-κB activation.
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エチオピアにおけるPlasmodium vivax Duffy Binding Proteinの頻発とその疫学的意義

Frequent expansion of Plasmodium vivax Duffy Binding Protein in Ethiopia and its epidemiological significance.
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