赤色複合菌、感染根管内細菌の検出と臨床症状との関連性

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J Family Med Prim Care.2020 Apr;9(4):1915-1920. JFMPC-9-1915. doi: 10.4103/jfmpc.jfmpc_1177_19.Epub 2020-04-30.

赤色複合菌、感染根管内細菌の検出と臨床症状との関連性

Detection of Red complex bacteria, , and in infected root canals and their association with clinical signs and symptoms.

Sonia Tiwari
Sudhanshu Saxena
Aarti Kumari
Silpi Chatterjee
Adreet Hazra
Alok Ratan Choudhary

PMID: 32670940 PMCID: PMC7346963. DOI: 10.4103/jfmpc.jfmpc_1177_19.

抄録

狙い目:

本研究の目的は，ポリメラーゼ連鎖反応（PCR）を用いて，歯内療法の臨床症状や徴候と , , , , , , , , , の存在との関連を調べることであった．

Aim: This study aimed to investigate the association between endodontic clinical signs and symptoms and the presence of , and employing polymerase chain reaction (PCR).

材料と方法:

原発性歯髄壊死性歯髄感染症60例から微生物サンプルを採取した．サンプルから抽出したDNAを種特異的プライマーを用いて歯内病原体の分析を行った．

Materials and Methods: Microbial samples were obtained from 60 cases with necrotic pulp with primary teeth infections. DNA extracted from samples were analyzed for endodontic pathogens by using species-specific primers.

結果:

痛みと腫脹を伴う症状のある15本の歯で検出された．疼痛と腫脹の臨床所見との関連においても統計学的に有意な関連が認められた．( < 0.05).赤色複合細菌は、徴候や症状の存在と統計的に有意な関連を示さなかった。

Results: were detected in 15 symptomatic teeth associated with periapical lesions. were found in 16 symptomatic teeth associated with pain and swelling. was detected in 9 teeth which were associated with pain, 2 with tenderness on percussion, and 15 with periapical lesions. Statistically significant associations were found between as well as in relation to clinical findings of pain and swelling. ( < 0.05). Red complex bacteria showed no statistical significant association with the presence of signs and symptoms.

結論:

の有病率が高く，これらの細菌と感染歯髄および歯周病との関連性が示唆された．

Conclusion: Prevalence of , , and suggested association of these bacteria with symptomatic infected pulp and periradicular diseases.