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日本語AIでPubMedを検索

歯科医師情報サイトTOP / PubMed論文検索

日本語AIでPubMedを検索

PubMedの提供する医学論文データベースを日本語で検索できます。AI(Deep Learning)を活用した機械翻訳エンジンにより、精度高く日本語へ翻訳された論文をご参照いただけます。
対象期間    ～ 

2020年07月 みんなが読んでいる論文

放射線治療中の骨エッジの自動検出に基づく電子ポータルイメージングデバイス画像の新しいレジストレーションアルゴリズム

A new registration algorithm of electronic portal imaging devices images based on the automatic detection of bone edges during radiotherapy.
  • Cheng Chen
  • Chaoyan Wu
  • Yahua Zhong
  • Conghua Xie
  • Yunfeng Zhou
  • Hui Liu
  • Jun Zhang
  • Jiuling Sheng
  • Dazheng Jiang
  • Hongli Zhao
  • Haijun Yu
  • Sci Rep.2020 Jun;10(1):10253. 10.1038/s41598-020-67331-9. doi: 10.1038/s41598-020-67331-9.Epub 2020-06-24.

韓国における多遺伝子標的配列決定法による遺伝性球状細胞症の分子診断：浸透圧脆弱性検査とのマッチングと球状細胞の存在

Molecular diagnosis of hereditary spherocytosis by multi-gene target sequencing in Korea: matching with osmotic fragility test and presence of spherocyte.
  • Hyoung Soo Choi
  • Qute Choi
  • Jung-Ah Kim
  • Kyong Ok Im
  • Si Nae Park
  • Yoomi Park
  • Hee Young Shin
  • Hyoung Jin Kang
  • Hoon Kook
  • Seon Young Kim
  • Soo-Jeong Kim
  • Inho Kim
  • Ji Yoon Kim
  • Hawk Kim
  • Kyung Duk Park
  • Kyung Bae Park
  • Meerim Park
  • Sang Kyu Park
  • Eun Sil Park
  • Jeong-A Park
  • Jun Eun Park
  • Ji Kyoung Park
  • Hee Jo Baek
  • Jeong Ho Seo
  • Ye Jee Shim
  • Hyo Seop Ahn
  • Keon Hee Yoo
  • Hoi Soo Yoon
  • Young-Woong Won
  • Kun Soo Lee
  • Kwang Chul Lee
  • Mee Jeong Lee
  • Sun Ah Lee
  • Jun Ah Lee
  • Jae Min Lee
  • Jae Hee Lee
  • Ji Won Lee
  • Young Tak Lim
  • Hyun Joo Jung
  • Hee Won Chueh
  • Eun Jin Choi
  • Hye Lim Jung
  • Ju Han Kim
  • Dong Soon Lee
  • Orphanet J Rare Dis.2019 05;14(1):114. 10.1186/s13023-019-1070-0. doi: 10.1186/s13023-019-1070-0.Epub 2019-05-23.

アルコールで活性化されたヒトおよびマウス肝細胞の一次培養肝細胞は、遺伝子発現プロファイルの類似性を共有する

Primary Alcohol-Activated Human and Mouse Hepatic Stellate Cells Share Similarities in Gene-Expression Profiles.
  • Xiao Liu
  • Sara Brin Rosenthal
  • Nairika Meshgin
  • Jacopo Baglieri
  • Sami G Musallam
  • Karin Diggle
  • Kevin Lam
  • Raymond Wu
  • Stephanie Q Pan
  • Yibu Chen
  • Ken Dorko
  • Sharon Presnell
  • Chris Benner
  • Mojgan Hosseini
  • Hidekazu Tsukamoto
  • David Brenner
  • Tatiana Kisseleva
  • Hepatol Commun.2020 Apr;4(4):606-626. HEP41483. doi: 10.1002/hep4.1483.Epub 2020-02-06.

機械学習予測モデルを利用した簡易デジタル睡眠問診票が、一般的な睡眠障害を特定します

Brief digital sleep questionnaire powered by machine learning prediction models identifies common sleep disorders.
  • Alan R Schwartz
  • Mairav Cohen-Zion
  • Luu V Pham
  • Amit Gal
  • Mudiaga Sowho
  • Francis P Sgambati
  • Tracy Klopfer
  • Michelle A Guzman
  • Erin M Hawks
  • Tamar Etzioni
  • Laura Glasner
  • Eran Druckman
  • Giora Pillar
  • Sleep Med..2020 Jul;71:66-76. S1389-9457(20)30117-9. doi: 10.1016/j.sleep.2020.03.005.Epub 2020-03-23.

コイヘルペスウイルス病の発生。南チロル-イタリアにおけるサーベイランスプログラム実施のためのインプット

Koi herpesvirus disease outbreak: Input for the implementation of a surveillance program in South Tyrol - Italy.
  • Stefano Colorio
  • Anna Toffan
  • Eva Lewisch
  • Manuela Dalla Pozza
  • Ernst Stifter
  • Andreas Pircher
  • Andreas Meraner
  • Astrid Bettini
  • Alexander Tavella
  • Prev. Vet. Med..2020 Jul;181:105089. S0167-5877(20)30193-8. doi: 10.1016/j.prevetmed.2020.105089.Epub 2020-07-06.

患者が報告したフレアの頻度は、全身性エリテマトーデスにおける生活の質の低下および家族の役割機能の低下と関連している

Patient-reported flare frequency is associated with diminished quality of life and family role functioning in systemic lupus erythematosus.
  • Patricia Katz
  • George J Wan
  • Paola Daly
  • Lauren Topf
  • Erin Connolly-Strong
  • Ryan Bostic
  • Michael L Reed
  • Qual Life Res.2020 Jul;10.1007/s11136-020-02572-9. doi: 10.1007/s11136-020-02572-9.Epub 2020-07-18.

酢酸-CoAリガーゼのフラグメンテーションは、NDP形成性アシル-CoA合成酵素スーパーファミリータンパク質のドメイン再配列の歴史を理解する手がかりを与えてくれる

Fragmentation of acetate-CoA ligase gives a clue to understand domain rearrangement history of NDP-forming acyl-CoA synthetase superfamily proteins.
  • Yoko Chiba
  • Mariko Shitara
  • Ken Takai
  • Biosci. Biotechnol. Biochem..2020 Jun;:1-9. doi: 10.1080/09168451.2020.1779581.Epub 2020-06-14.

フルターム低出生体重児は、免疫系と臓器の成長に関連するハイメチル化DNAが異なる：フルターム正常出生体重児との比較

Full-term low birth weight infants have differentially hypermethylated DNA related to immune system and organ growth: a comparison with full-term normal birth weight infants.
  • Ikuyo Hayashi
  • Ken Yamaguchi
  • Masahiro Sumitomo
  • Kenji Takakura
  • Narumi Nagai
  • Naoki Sakane
  • BMC Res Notes.2020 Apr;13(1):199. 10.1186/s13104-020-04961-2. doi: 10.1186/s13104-020-04961-2.Epub 2020-04-03.

思春期の若者のメンタルヘルスを改善するための関係性に焦点を当てた携帯電話アプリケーションの無作為化比較試験

A randomised controlled trial of a relationship-focussed mobile phone application for improving adolescents' mental health.
  • Bridianne O'Dea
  • Jin Han
  • Philip J Batterham
  • Melinda R Achilles
  • Alison L Calear
  • Aliza Werner-Seidler
  • Belinda Parker
  • Fiona Shand
  • Helen Christensen
  • J Child Psychol Psychiatry.2020 Jul;doi: 10.1111/jcpp.13294.Epub 2020-07-19.

ミトコンドリアペプチダーゼPITRM1の機能喪失は、ヒトの脳内オルガノイドにおいて、タンパク質毒性ストレスとアルツハイマー病様の病態を誘導することが明らかになった

Loss of function of the mitochondrial peptidase PITRM1 induces proteotoxic stress and Alzheimer's disease-like pathology in human cerebral organoids.
  • María José Pérez
  • Dina Ivanyuk
  • Vasiliki Panagiotakopoulou
  • Gabriele Di Napoli
  • Stefanie Kalb
  • Dario Brunetti
  • Rawaa Al-Shaana
  • Stephan A Kaeser
  • Sabine Anne-Kristin Fraschka
  • Mathias Jucker
  • Massimo Zeviani
  • Carlo Viscomi
  • Michela Deleidi
  • Mol. Psychiatry.2020 Jul;10.1038/s41380-020-0807-4. doi: 10.1038/s41380-020-0807-4.Epub 2020-07-07.

ヒト気道上皮細胞培養におけるSARS-CoV-2およびマウスにおける複数のコロナウイルスを阻害する経口生物学的に利用可能な広汎な抗ウイルス剤です

An orally bioavailable broad-spectrum antiviral inhibits SARS-CoV-2 in human airway epithelial cell cultures and multiple coronaviruses in mice.
  • Timothy P Sheahan
  • Amy C Sims
  • Shuntai Zhou
  • Rachel L Graham
  • Andrea J Pruijssers
  • Maria L Agostini
  • Sarah R Leist
  • Alexandra Schäfer
  • Kenneth H Dinnon
  • Laura J Stevens
  • James D Chappell
  • Xiaotao Lu
  • Tia M Hughes
  • Amelia S George
  • Collin S Hill
  • Stephanie A Montgomery
  • Ariane J Brown
  • Gregory R Bluemling
  • Michael G Natchus
  • Manohar Saindane
  • Alexander A Kolykhalov
  • George Painter
  • Jennifer Harcourt
  • Azaibi Tamin
  • Natalie J Thornburg
  • Ronald Swanstrom
  • Mark R Denison
  • Ralph S Baric
  • Sci Transl Med.2020 04;12(541). eabb5883. doi: 10.1126/scitranslmed.abb5883.Epub 2020-04-06.

非選択的エンドセリン受容体拮抗薬であるボセンタンは、マウスの肺高血圧症を改善する骨髄由来細胞の動態を調節する

A non-selective endothelin receptor antagonist bosentan modulates kinetics of bone marrow-derived cells in ameliorating pulmonary hypertension in mice.
  • Taichi Kato
  • Yoshihide Mitani
  • Masahiro Masuya
  • Junko Maruyama
  • Hirofumi Sawada
  • Hiroyuki Ohashi
  • Yukiko Ikeyama
  • Shoichiro Otsuki
  • Noriko Yodoya
  • Tsutomu Shinohara
  • Eri Miyata
  • Erquan Zhang
  • Naoyuki Katayama
  • Hideto Shimpo
  • Kazuo Maruyama
  • Yoshihiro Komada
  • Masahiro Hirayama
  • Pulm Circ.2020 Apr-Jun;10(2):2045894020919355. 10.1177_2045894020919355. doi: 10.1177/2045894020919355.Epub 2020-05-14.

大気/液界面(ALI)曝露システムを用いた工業用VOCの触媒酸化除去による排出物のin vitro毒物学的評価

In vitro toxicological evaluation of emissions from catalytic oxidation removal of industrial VOCs by air/liquid interface (ALI) exposure system in repeated mode.
  • Clémence Méausoone
  • Rebecca El Khawaja
  • Gauthier Tremolet
  • Stéphane Siffert
  • Renaud Cousin
  • Fabrice Cazier
  • Sylvain Billet
  • Dominique Courcot
  • Yann Landkocz
  • Toxicol In Vitro.2019 Aug;58:110-117. S0887-2333(18)30782-3. doi: 10.1016/j.tiv.2019.03.030.Epub 2019-03-22.

磁性グラフェン酸化物分散固相抽出法をベースとしたポータブルイオンモビリティースペクトロメトリーによる唾液・尿中の5種類の抗過敏症薬の定量のための迅速かつ簡便なアプローチをご紹介します

A fast and simple approach for the quantification of five anti-hypersensitivity drugs in saliva and urine by portable ion mobility spectrometry based on magnetic graphene oxide dispersive solid phase extraction.
  • Yixuan Cui
  • Di Liu
  • Mengqiang Zhao
  • Junmei Li
  • Yuke Yang
  • Mengjiao Li
  • Jinglin Gao
  • Ye Jiang
  • J Pharm Biomed Anal.2020 Jun;189:113414. S0731-7085(20)31300-5. doi: 10.1016/j.jpba.2020.113414.Epub 2020-06-10.

新規ヘテロ接合性ABCG8変異とSLC4A2多型による肝内胆石症とウルソデオキシコール酸下での良好な成績．

Intrahepatic Cholestasis Owing to a Novel Heterozygous ABCG8 Mutation and SLC4A2 Polymorphism With Favorable Outcome Under Ursodeoxycholic Acid.
  • Dragos Ciocan
  • Cosmin Sebastian Voican
  • Véronique Barbu
  • Christophe Corpechot
  • Dominique Rainteau
  • Sophie Prevot
  • Amandine Lebrun
  • Gabriel Perlemuter
  • Am. J. Gastroenterol..2019 09;114(9):1556-1559. doi: 10.14309/ajg.0000000000000328.

分光技術とケモメトリクスを組み合わせることで、違法と疑われる抗菌薬の迅速な現場での特性評価が可能になります

Spectroscopic techniques combined with chemometrics for fast on-site characterization of suspected illegal antimicrobials.
  • Yaxin Tie
  • Céline Duchateau
  • Shana Van de Steene
  • Corenthin Mees
  • Kris De Braekeleer
  • Thomas De Beer
  • Erwin Adams
  • Eric Deconinck
  • Talanta.2020 Sep;217:121026. S0039-9140(20)30317-9. doi: 10.1016/j.talanta.2020.121026.Epub 2020-04-18.

高い分散能力と生物地理学的断絶が、世界的に分布する岩礁棲息性カルシファイヤーの遺伝的多様性を形成している

High dispersal capacity and biogeographic breaks shape the genetic diversity of a globally distributed reef-dwelling calcifier.
  • Martina Prazeres
  • Raphaël Morard
  • T Edward Roberts
  • Steve S Doo
  • Jamaluddin Jompa
  • Christiane Schmidt
  • Marleen Stuhr
  • Willem Renema
  • Michal Kucera
  • Ecol Evol.2020 Jun;10(12):5976-5989. ECE36335. doi: 10.1002/ece3.6335.Epub 2020-05-14.

動的結腸モデル（DCM）。ポジトロンイメージング技術を用いて特徴づけられたヒト近位大腸のCine-MRIを用いた生体関連インビトロモデル

Dynamic Colon Model (DCM): A Cine-MRI Informed Biorelevant In Vitro Model of the Human Proximal Large Intestine Characterized by Positron Imaging Techniques.
  • Konstantinos Stamatopoulos
  • Sharad Karandikar
  • Mark Goldstein
  • Connor O'Farrell
  • Luca Marciani
  • Sarah Sulaiman
  • Caroline L Hoad
  • Mark J H Simmons
  • Hannah K Batchelor
  • Pharmaceutics.2020 Jul;12(7). E659. doi: 10.3390/pharmaceutics12070659.Epub 2020-07-13.

Ex vivoで拡張された自己脂肪組織由来の間質細胞は、豊胸手術における脂肪移植片の保持力の向上を確実にします。無作為化比較臨床試験

Ex vivo-expanded autologous adipose tissue-derived stromal cells ensure enhanced fat graft retention in breast augmentation: A randomized controlled clinical trial.
  • Stig-Frederik T Kølle
  • Dominik Duscher
  • Mikkel Taudorf
  • Anne Fischer-Nielsen
  • Jesper D Svalgaard
  • Lea Munthe-Fog
  • Bo Jønsson
  • Peter B Selvig
  • Frederik P Mamsen
  • Adam J Katz
  • Stem Cells Transl Med.2020 Jul;doi: 10.1002/sctm.20-0081.Epub 2020-07-08.

ビフィズス菌は、シナプス形成とミクログリア機能を促進することで、生後の発生期に宿主の神経回路を形成している

Bifidobacteria shape host neural circuits during postnatal development by promoting synapse formation and microglial function.
  • Berkley Luck
  • Melinda A Engevik
  • Bhanu Priya Ganesh
  • Elizabeth P Lackey
  • Tao Lin
  • Miriam Balderas
  • Angela Major
  • Jessica Runge
  • Ruth Ann Luna
  • Roy V Sillitoe
  • James Versalovic
  • Sci Rep.2020 May;10(1):7737. 10.1038/s41598-020-64173-3. doi: 10.1038/s41598-020-64173-3.Epub 2020-05-08.

胃癌に対する手術安全性と機能的利益における幽門温存術と遠位胃切除術の比較：システマティックレビューとメタアナリシス

A comparison between pylorus-preserving and distal gastrectomy in surgical safety and functional benefit with gastric cancer: a systematic review and meta-analysis.
  • Xinyu Mao
  • Xinlei Xu
  • Hua Zhu
  • Chunpeng Ji
  • Xu Lu
  • Baolin Wang
  • World J Surg Oncol.2020 Jul;18(1):160. 10.1186/s12957-020-01910-y. doi: 10.1186/s12957-020-01910-y.Epub 2020-07-08.

株ＤＸＬ由来の食品酵素エンド-１，４-β-キシラナーゼおよびβ-グルカナーゼの安全性評価

Safety evaluation of the food enzyme endo-1,4-β-xylanase and β-glucanase from strain DXL.
  • Vittorio Silano
  • José Manuel Barat Baviera
  • Claudia Bolognesi
  • Pier Sandro Cocconcelli
  • Riccardo Crebelli
  • David Michael Gott
  • Konrad Grob
  • Evgenia Lampi
  • Alicja Mortensen
  • Gilles Rivière
  • Inger-Lise Steffensen
  • Christina Tlustos
  • Henk Van Loveren
  • Laurence Vernis
  • Holger Zorn
  • Boet Glandorf
  • Lieve Herman
  • Francesca Marcon
  • André Penninks
  • Andrew Smith
  • Margarita Aguilera-Gomez
  • Magdalena Andryszkiewicz
  • Davide Arcella
  • Ana Gomes
  • Natália Kovalkovičová
  • Yi Liu
  • Joaquim Maia
  • Claudia Roncancio Peña
  • Andrew Chesson
  • EFSA J.2020 Jan;18(1):e05975. EFS25975. doi: 10.2903/j.efsa.2020.5975.Epub 2020-01-10.

COVID-19パンデミック後の学術放射線科におけるオペレーショナル・ラジオロジー・リカバリー。正常化に向けての動き

Operational Radiology Recovery in Academic Radiology Departments After the COVID-19 Pandemic: Moving Toward Normalcy.
  • Daniel S Siegal
  • Brooke Wessman
  • Jessica Zadorozny
  • Josie Palazzolo
  • Alysia Montana
  • James V Rawson
  • Alexander Norbash
  • Manuel L Brown
  • J Am Coll Radiol.2020 Jul;S1546-1440(20)30748-1. doi: 10.1016/j.jacr.2020.07.004.Epub 2020-07-11.

伝統的なホメオパシー的に製造された金属（Cuprum metallicum）と植物（Gelsemium sempervirens）の医薬品とコントロールの核磁気共鳴特性の検証

Verification of Nuclear Magnetic Resonance Characterization of Traditional Homeopathically Manufactured Metal (Cuprum metallicum) and Plant (Gelsemium sempervirens) Medicines and Controls.
  • Michel Van Wassenhoven
  • Martine Goyens
  • Marc Henry
  • Jean Cumps
  • Philippe Devos
  • Homeopathy.2020 Jul;doi: 10.1055/s-0040-1710022.Epub 2020-07-02.

自己拡張型EvololutR弁を用いたTAVRにおける患者特定コンピュータシミュレーション

Patient-Specific Computer Simulation in TAVR With the Self-Expanding Evolut R Valve.
  • Nahid El Faquir
  • Ole De Backer
  • Johan Bosmans
  • Tanja Rudolph
  • Nicola Buzzatti
  • Gintautas Bieliauskas
  • Valerie Collas
  • Hendrik Wienemann
  • Davide Schiavi
  • Paul Cummins
  • Zouhair Rahhab
  • Herbert Kroon
  • Quinten Wolff
  • Mattie Lenzen
  • Joana Maria Ribeiro
  • Azeem Latib
  • Matti Adam
  • Lars Søndergaard
  • Ben Ren
  • Nicolas Van Mieghem
  • Peter de Jaegere
  • JACC Cardiovasc Interv.2020 Jul;S1936-8798(20)30959-6. doi: 10.1016/j.jcin.2020.04.018.Epub 2020-07-08.

ヒトのBDNF/TrkB変異体は海馬のシナプス形成を阻害し、神経行動異常と関連している

Human BDNF/TrkB variants impair hippocampal synaptogenesis and associate with neurobehavioural abnormalities.
  • Takuhiro Sonoyama
  • Lukas K J Stadler
  • Mingyan Zhu
  • Julia M Keogh
  • Elana Henning
  • Fuki Hisama
  • Peter Kirwan
  • Magdalena Jura
  • Beata K Blaszczyk
  • David C DeWitt
  • Bas Brouwers
  • Marko Hyvönen
  • Inês Barroso
  • Florian T Merkle
  • Suzanne M Appleyard
  • Gary A Wayman
  • I Sadaf Farooqi
  • Sci Rep.2020 Jun;10(1):9028. 10.1038/s41598-020-65531-x. doi: 10.1038/s41598-020-65531-x.Epub 2020-06-03.

常に再生可能な接触殺傷抗菌表面と抗バイオフィルムおよび無抽出特性を有するバイオミメティックな生分解性Ag@Auナノ粒子包埋尿管ステント

Biomimetic biodegradable Ag@Au nanoparticle-embedded ureteral stent with a constantly renewable contact-killing antimicrobial surface and antibiofilm and extraction-free properties.
  • Liheng Gao
  • Yiwei Wang
  • Yimeng Li
  • Mingxi Xu
  • Gang Sun
  • Ting Zou
  • Fujun Wang
  • Sijun Xu
  • Jun Da
  • Lu Wang
  • Acta Biomater.2020 Jul;S1742-7061(20)30411-6. doi: 10.1016/j.actbio.2020.07.025.Epub 2020-07-16.

コートジボワールにおける2007年から2016年までの急性弛緩性麻痺のサーベイランス。非ポリウイルス性エンテロウイルスの意義と疫学的プロファイル

[Surveillance of acute flaccid paralysis in Ivory Coast between 2007 and 2016: Significance and epidemiological profile of non-poliovirus enteroviruses].
  • Lepri Bernadin Nicaise Aka
  • Kouadio Daniel Ekra
  • Gnissan Henri Auguste Yao
  • Alfred Douba
  • Bangaman Christian Akani
  • Zakaria Keita
  • Serge Aimé Dali
  • Kassoum Kayentao
  • Hamadoun Sangho
  • Doumbia Seydou
  • Sante Publique.2019 November December;31(6):837-843. doi: 10.3917/spub.196.0837.

A Clinicopathological Approach to Odontogenic Cysts: the Role of Cytokeratin 17 and bcl2 Immunohistochemistry in Identifying Odontogenic Keratocysts

A Clinicopathological Approach to Odontogenic Cysts: the Role of Cytokeratin 17 and bcl2 Immunohistochemistry in Identifying Odontogenic Keratocysts.
  • Dorottya Cserni
  • Tamás Zombori
  • András Vörös
  • Anette Stájer
  • Annamária Rimovszki
  • Krisztián Daru
  • Zoltán Baráth
  • Gábor Cserni
  • Pathol. Oncol. Res..2020 Jul;10.1007/s12253-020-00866-4. doi: 10.1007/s12253-020-00866-4.Epub 2020-07-06.

ショウジョウバエの進化の過程における遺伝子座のヘテロクロマチンへの適応は、インシュレータータンパク質と関連している

Adaptation of gene loci to heterochromatin in the course of Drosophila evolution is associated with insulator proteins.
  • Sergei Yu Funikov
  • Alexander P Rezvykh
  • Dina A Kulikova
  • Elena S Zelentsova
  • Lyudmila A Protsenko
  • Lyubov N Chuvakova
  • Venera I Tyukmaeva
  • Irina R Arkhipova
  • Michael B Evgen'ev
  • Sci Rep.2020 Jul;10(1):11893. 10.1038/s41598-020-68879-2. doi: 10.1038/s41598-020-68879-2.Epub 2020-07-17.

横隔膜NMJの神経筋接合部の神経支配はsGC/cGMPシグナルによって制御されているか？

Is Innervation of the Neuromuscular Junction at the Diaphragm Modulated by sGC/cGMP Signaling?
  • Nadežda Lukáčová
  • L'udmila Hricová
  • Alexandra Kisucká
  • Štefánia Papcunová
  • Katarína Bimbová
  • Mária Bačová
  • Jaroslav Pavel
  • Martin Marsala
  • Ivo Vanický
  • Zuzana Dzurjašková
  • Stanislav Matéffy
  • Viktória Lukáčová
  • Andrea Stropkovská
  • Ján Gálik
  • Front Physiol.2020;11:700. doi: 10.3389/fphys.2020.00700.Epub 2020-06-23.

識別とメラノーマ関連網膜症患者の血清からの新規 TRPM1 自己抗体の特徴付け

Identification and characterization of novel TRPM1 autoantibodies from serum of patients with melanoma-associated retinopathy.
  • Juliette Varin
  • Margaret M Reynolds
  • Nassima Bouzidi
  • Sarah Tick
  • Juliette Wohlschlegel
  • Ondine Becquart
  • Christelle Michiels
  • Olivier Dereure
  • Robert M Duvoisin
  • Catherine W Morgans
  • José-Alain Sahel
  • Quentin Samaran
  • Bernard Guillot
  • José S Pulido
  • Isabelle Audo
  • Christina Zeitz
  • PLoS ONE.2020;15(4):e0231750. PONE-D-19-30946. doi: 10.1371/journal.pone.0231750.Epub 2020-04-23.

核磁気共鳴イメージングによる癌の生体分布の可視化のためのペプチド・トランスポーター標的化Fdipeptidesの有用性の可能性

Possible utility of peptide-transporter-targeting [F]dipeptides for visualization of the biodistribution of cancers by nuclear magnetic resonance imaging.
  • Hiroshi Arakawa
  • Hiroyuki Yamada
  • Kazutaka Arai
  • Takumi Kawanishi
  • Nobuhiro Nitta
  • Sayaka Shibata
  • Eiko Matsumoto
  • Kentaro Yano
  • Yukio Kato
  • Takuya Kumamoto
  • Ichio Aoki
  • Takuo Ogihara
  • Int J Pharm.2020 Jul;586:119575. S0378-5173(20)30559-7. doi: 10.1016/j.ijpharm.2020.119575.Epub 2020-07-02.

スポーツ傷害研究における方法に関する声明 第1回METHODS MATTER会議、コペンハーゲン、2019年より

Statement on Methods in Sport Injury Research From the First METHODS MATTER Meeting, Copenhagen, 2019.
  • Rasmus Østergaard Nielsen
  • Ian Shrier
  • Martí Casals
  • Alberto Nettel-Aguirre
  • Merete Møller
  • Caroline Bolling
  • Nataliá F N Bittencourt
  • Ben Clarsen
  • Niels Wedderkopp
  • Torbjørn Soligard
  • Toomas Timpka
  • Carolyn A Emery
  • Roald Bahr
  • Jenny Jacobsson
  • Rod Whiteley
  • Örjan Dahlström
  • Nicol van Dyk
  • Babette M Pluim
  • Emmanuel Stamatakis
  • Luz Palacios-Derflingher
  • Morten W Fagerland
  • Karim M Khan
  • Clare L Ardern
  • Evert Verhagen
  • J Orthop Sports Phys Ther.2020 May;50(5):226-233. doi: 10.2519/jospt.2020.9876.

WRKY55転写因子は、シロイヌナズナの活性酸素とサリチル酸の生合成に関与する遺伝子の転写を調節することで、葉の老化と防御応答を正に制御している

WRKY55 transcription factor positively regulates leaf senescence and defense response through modulating the transcription of genes implicated in ROS and SA biosynthesis in Arabidopsis.
  • Yiqiao Wang
  • Xing Cui
  • Bo Yang
  • Shutao Xu
  • Xiangyan Wei
  • Peiyu Zhao
  • Fangfang Niu
  • Mengting Sun
  • Chen Wang
  • Hao Cheng
  • Yuan-Qing Jiang
  • Development.2020 Jul;dev.189647. doi: 10.1242/dev.189647.Epub 2020-07-17.

メトホルミン塩酸塩の徐放性を制御して線維化を緩和し、創傷治癒を促進するための二重機能を持つ3層構造の足場の設計、作製、最適化

Design, fabrication, and optimization of a dual function three-layer scaffold for controlled release of metformin hydrochloride to alleviate fibrosis and accelerate wound healing.
  • Faraz Chogan
  • Tahereh Mirmajidi
  • Ali Hossein Rezayan
  • Ali Mohammad Sharifi
  • Aziz Ghahary
  • Jhamak Nourmohammadi
  • Amir Kamali
  • Mahdi Rahaie
  • Acta Biomater.2020 Jun;S1742-7061(20)30361-5. doi: 10.1016/j.actbio.2020.06.031.Epub 2020-06-23.

nCOVID-19の免疫病態と、効果的な治療と死亡者数の減少のための抗炎症・抗ウイルスプロスタグランジン（PG J）を含む宿主指示療法の可能性

Immuno-pathogenesis of nCOVID-19 and a possible host-directed therapy including anti-inflammatory and anti-viral prostaglandin (PG J) for effective treatment and reduction in the death toll.
  • Shakeel Shahzad
  • Mark Willcox
  • Med. Hypotheses.2020 Jul;143:110080. S0306-9877(20)31926-5. doi: 10.1016/j.mehy.2020.110080.Epub 2020-07-08.

麹菌のクロロフィル生合成と初期葉緑体発生を制御する黄色蛍光遺伝子の特性評価とファインマップの作成

Characterization and Fine Mapping of a Yellow-Virescent Gene Regulating Chlorophyll Biosynthesis and Early Stage Chloroplast Development in .
  • Chuanji Zhao
  • Lijiang Liu
  • Luqman Bin Safdar
  • Meili Xie
  • Xiaohui Cheng
  • Yueying Liu
  • Yang Xiang
  • Chaobo Tong
  • Jinxing Tu
  • Junyan Huang
  • Shengyi Liu
  • G3 (Bethesda).2020 Jul;g3.401460.2020. doi: 10.1534/g3.120.401460.Epub 2020-07-09.

軟骨石灰化は、膝関節の組織学的変性と関連している：非常に普及している、年齢に依存しない全身性のプロセス

Cartilage calcification is associated with histological degeneration of the knee joint: a highly prevalent, age-independent systemic process.
  • Jan Hubert
  • Frank Timo Beil
  • Tim Rolvien
  • Sebastian Butscheidt
  • Sandra Hischke
  • Klaus Püschel
  • Stephan Frosch
  • Haider Mussawy
  • Christian Ries
  • Thelonius Hawellek
  • Osteoarthr. Cartil..2020 Jul;S1063-4584(20)31063-3. doi: 10.1016/j.joca.2020.04.020.Epub 2020-07-16.

市販のホエイ製品は、細菌性エンドトキシン・リポ多糖類（LPS）誘発炎症をin vitroで抑制するグリコマクロペプチド強化活性を有し、腸管バリア機能を促進する

Commercial whey products promote intestinal barrier function with glycomacropeptide enhanced activity in downregulating bacterial endotoxin lipopolysaccharides (LPS)-induced inflammation in vitro.
  • Shirley Arbizu
  • Boon Chew
  • Susanne U Mertens-Talcott
  • Giuliana Noratto
  • Food Funct.2020 Jul;doi: 10.1039/d0fo00487a.Epub 2020-07-07.

ジペプチジルペプチダーゼ-4阻害薬シタグリプチンは、KvチャネルとPKAの活性化を介して血管弛緩を誘導する

Dipeptidyl peptidase-4 inhibitor sitagliptin induces vasorelaxation via the activation of Kv channels and PKA.
  • Hongliang Li
  • Mi Seon Seo
  • Jin Ryeol An
  • Hee Seok Jung
  • Kwon-Soo Ha
  • Eun-Taek Han
  • Seok-Ho Hong
  • Young Min Bae
  • Sung Hun Na
  • Won Sun Park
  • Toxicol. Appl. Pharmacol..2019 12;384:114799. S0041-008X(19)30407-7. doi: 10.1016/j.taap.2019.114799.Epub 2019-10-31.

ペメトレキセド化学療法が患者肺由来腫瘍異種移植（PDX）マウスモデルの腸内マイクロバイオータおよび腸内炎症に及ぼす影響

Impact of pemetrexed chemotherapy on the gut microbiota and intestinal inflammation of patient-lung-derived tumor xenograft (PDX) mouse models.
  • Cindy Pensec
  • Florence Gillaizeau
  • Dominique Guenot
  • Anne Bessard
  • Thomas Carton
  • Sébastien Leuillet
  • Mario Campone
  • Michel Neunlist
  • Hervé M Blottière
  • Françoise Le Vacon
  • Sci Rep.2020 Jun;10(1):9094. 10.1038/s41598-020-65792-6. doi: 10.1038/s41598-020-65792-6.Epub 2020-06-04.

新規抗がん剤として期待されるフェニルクロルメチン-キナゾリン誘導体の合成、Sirt1/caspase3シグナル伝達経路を介して肝細胞がんのアポトーシスを誘導した

Synthesis of a New Phenyl Chlormethine-Quinazoline Derivative, a Potential Anti-Cancer Agent, Induced Apoptosis in Hepatocellular Carcinoma Through Mediating Sirt1/Caspase 3 Signaling Pathway.
  • Jia-Jia Lv
  • Wen-Ting Song
  • Xin-Min Li
  • Jian-Mei Gao
  • Ze-Li Yuan
  • Front Pharmacol.2020;11:911. doi: 10.3389/fphar.2020.00911.Epub 2020-06-26.

低リスクの小児急性骨髄性白血病における良好な転帰を維持しつつ、アントラサイクリンの累積曝露を減らす戦略

A strategy to reduce cumulative anthracycline exposure in low-risk pediatric acute myeloid leukemia while maintaining favorable outcomes.
  • Himalee S Sabnis
  • Katherine A Minson
  • Caitlin Monroe
  • Kristen Allen
  • Jonathan L Metts
  • Todd M Cooper
  • William G Woods
  • Sharon M Castellino
  • Frank G Keller
  • Leuk. Res..2020 Jul;96:106421. S0145-2126(20)30126-0. doi: 10.1016/j.leukres.2020.106421.Epub 2020-07-12.

タンパク質ネットワーク解析により、AECOPD患者の血小板脱顆粒、タンパク質分解、コレステロール代謝経路に関与するタンパク質のレベルの変化が明らかになった

Protein Network Analysis Identifies Changes in the Level of Proteins Involved in Platelet Degranulation, Proteolysis and Cholesterol Metabolism Pathways in AECOPD Patients.
  • Dino B A Tan
  • Jason Ito
  • Kirsten Peters
  • Andreja Livk
  • Richard J Lipscombe
  • Tammy M Casey
  • Yuben P Moodley
  • COPD.2020 Feb;17(1):29-33. doi: 10.1080/15412555.2019.1711035.Epub 2020-01-10.

また、トリソミー21脳内オルガノイドの患者特異的アルツハイマー様病態を明らかにし、BACE2がヒト脳内のADサプレッサー遺伝子であることを明らかにした

Patient-specific Alzheimer-like pathology in trisomy 21 cerebral organoids reveals BACE2 as a gene dose-sensitive AD suppressor in human brain.
  • Ivan Alić
  • Pollyanna A Goh
  • Aoife Murray
  • Erik Portelius
  • Eleni Gkanatsiou
  • Gillian Gough
  • Kin Y Mok
  • David Koschut
  • Reinhard Brunmeir
  • Yee Jie Yeap
  • Niamh L O'Brien
  • Jürgen Groet
  • Xiaowei Shao
  • Steven Havlicek
  • N Ray Dunn
  • Hlin Kvartsberg
  • Gunnar Brinkmalm
  • Rosalyn Hithersay
  • Carla Startin
  • Sarah Hamburg
  • Margaret Phillips
  • Konstantin Pervushin
  • Mark Turmaine
  • David Wallon
  • Anne Rovelet-Lecrux
  • Hilkka Soininen
  • Emanuela Volpi
  • Joanne E Martin
  • Jia Nee Foo
  • David L Becker
  • Agueda Rostagno
  • Jorge Ghiso
  • Željka Krsnik
  • Goran Šimić
  • Ivica Kostović
  • Dinko Mitrečić
  • Paul T Francis
  • Kaj Blennow
  • Andre Strydom
  • John Hardy
  • Henrik Zetterberg
  • Dean Nižetić
  • Mol. Psychiatry.2020 Jul;10.1038/s41380-020-0806-5. doi: 10.1038/s41380-020-0806-5.Epub 2020-07-10.

再生不良性貧血に対するアンドロゲンステロイドの長期投与に伴う多発性肝細胞腺腫。症例報告と文献レビュー

Multiple hepatocellular adenomas associated with long-term administration of androgenic steroids for aplastic anemia: A case report and literature review.
  • Lixia Wang
  • Cong Wang
  • Wei Li
  • Fanyang Meng
  • Yuying Li
  • Hongqiong Fan
  • Yanhua Zhou
  • Gnana Bharathi
  • Sujun Gao
  • Yan Yang
  • Medicine (Baltimore).2020 Jul;99(28):e20829. 00005792-202007100-00027. doi: 10.1097/MD.0000000000020829.

単一カラムクロマトグラフィー分離とSF-ICP-MS分析を組み合わせた中分解能モードでの河川水中のラジウム226の簡易かつ高感度測定

Simple and sensitive determination of radium-226 in river water by single column-chromatographic separation coupled to SF-ICP-MS analysis in medium resolution mode.
  • Guosheng Yang
  • Jian Zheng
  • Keiko Tagami
  • Shigeo Uchida
  • Jing Zhang
  • Jinlong Wang
  • Jinzhou Du
  • J Environ Radioact.2020 Sep;220-221:106305. S0265-931X(20)30178-8. doi: 10.1016/j.jenvrad.2020.106305.Epub 2020-05-25.

特定の有機炭素源を用いた石油生産に伴うTENORMスケール廃棄物中のラジウム同位体溶解の速度論とメカニズム：乳酸溶液を用いたケーススタディ

Kinetics and mechanism of radium-isotopes dissolution in TENORM scale waste associated with petroleum production using certain organic carbon source: lactic acid solution-case study.
  • Elsayed M El Afifi
  • Ahmed M Shahr El-Din
  • Moustafa A Hilal
  • Environ Sci Pollut Res Int.2020 Jul;10.1007/s11356-020-09863-1. doi: 10.1007/s11356-020-09863-1.Epub 2020-07-03.

また、重症硫黄マスタード眼損傷者の涙および血清MMP-9および血清TIMPsレベルを評価した

Tear and serum MMP-9 and serum TIMPs levels in the severe sulfur mustard eye injured exposed patients.
  • Hassan Ghasemi
  • Roya Yaraee
  • Soghrat Faghihzadeh
  • Mohammad Ghassemi-Broumand
  • Mahmoud Mahmoudi
  • Mahmoud Babaei
  • Mostafa Naderi
  • Maliheh Safavi
  • Zeinab Ghazanfari
  • Maryam Rastin
  • Shahrzad Zamani
  • Nafiseh Tabasi
  • Elham Faghihzadeh
  • Reza Gharebaghi
  • Zuhair Mohammad Hassan
  • Ensie Sadat Mirsharif
  • Tooba Ghazanfari
  • Int. Immunopharmacol..2019 Dec;77:105812. S1567-5769(19)31188-9. doi: 10.1016/j.intimp.2019.105812.Epub 2019-10-31.

葉緑体のカリウム流出防止因子は、それぞれ光合成に影響を与え、短日光環境下での完全に発達したシロイヌナズナのロゼットの成長にも影響を与えている

Each of the chloroplast potassium efflux antiporters affects photosynthesis and growth of fully developed Arabidopsis rosettes under short-day photoperiod.
  • Somnath Dana
  • Andrei Herdean
  • Björn Lundin
  • Cornelia Spetea
  • Physiol Plant.2016 Dec;158(4):483-491. doi: 10.1111/ppl.12452.Epub 2016-06-09.

Erv14カーゴ受容体は酵母の耐塩性に関与しており、その相互作用は膜上のNha1カチオン/プロトンアンチポーターとの相互作用を介しています

Erv14 cargo receptor participates in yeast salt tolerance via its interaction with the plasma-membrane Nha1 cation/proton antiporter.
  • Paul Rosas-Santiago
  • Olga Zimmermannova
  • Rosario Vera-Estrella
  • Hana Sychrová
  • Omar Pantoja
  • Biochim. Biophys. Acta.2016 Jan;1858(1):67-74. S0005-2736(15)00328-4. doi: 10.1016/j.bbamem.2015.09.024.Epub 2015-10-09.

TheraP：進行性転移性去勢抵抗性前立腺がんを対象としたLu-PSMA-617セラノシス治療 vs カバジタキセルの無作為化第2相試験（Clinical Trial Protocol ANZUP 1603）

TheraP: a randomized phase 2 trial of Lu-PSMA-617 theranostic treatment vs cabazitaxel in progressive metastatic castration-resistant prostate cancer (Clinical Trial Protocol ANZUP 1603).
  • Michael S Hofman
  • Louise Emmett
  • John Violet
  • Alison Y Zhang
  • Nicola J Lawrence
  • Martin Stockler
  • Roslyn J Francis
  • Amir Iravani
  • Scott Williams
  • Arun Azad
  • Andrew Martin
  • Margaret McJannett
  • Ian D Davis
  • BJU Int..2019 11;124 Suppl 1:5-13. doi: 10.1111/bju.14876.Epub 2019-10-22.

mTORの阻害は、実験的な虚脱性局所セグメント糸球体硬化症を遅らせるが、予防することはできなかった

Inhibition of mTOR delayed but could not prevent experimental collapsing focal segmental glomerulosclerosis.
  • Laura Miesen
  • Jennifer Eymael
  • Shagun Sharma
  • Markus A Loeven
  • Brigith Willemsen
  • Marinka Bakker-van Bebber
  • Fieke Mooren
  • Catherine Meyer-Schwesinger
  • Henry Dijkman
  • Jack F M Wetzels
  • Jitske Jansen
  • Johan van der Vlag
  • Bart Smeets
  • Sci Rep.2020 May;10(1):8580. 10.1038/s41598-020-65352-y. doi: 10.1038/s41598-020-65352-y.Epub 2020-05-22.

植物由来の生物活性物質の抗がん作用の可能性についての洞察。前立腺癌に焦点を当てる

Insights on the anticancer potential of plant-food bioactives: A key focus to prostate cancer.
  • Bahare Salehi
  • Patrick Valere Tsouh Fokou
  • Lauve Rachel Tchokouaha Yamthe
  • Brice Tchatat Tali
  • Charles Oluwaseun Adetunji
  • Amirhossein Rahavian
  • Fhatuwani Nixwell Mudau
  • Natália Martins
  • Miquel Martorell
  • Célia F Rodrigues
  • William N Setzer
  • Mehdi Sharifi-Rad
  • Ryszard Amarowicz
  • Javad Sharifi-Rad
  • Cell. Mol. Biol. (Noisy-le-grand).2020 Jun;66(4):250-263. Epub 2020-06-25.

非虚血性心筋症における心室頻拍アブレーション後の長期成績。晩期の電位廃止とVT非誘導性

Long-Term Outcome after Ventricular Tachycardia Ablation in Non-Ischemic Cardiomyopathy: Late Potential Abolition and VT Noninducibility.
  • Kenji Okubo
  • Lorenzo Gigli
  • Nicola Trevisi
  • Luca Foppoli
  • Andrea Radinovic
  • Caterina Bisceglia
  • Antonio Frontera
  • Giuseppe D'Angelo
  • Manuela Cireddu
  • Gabriele Paglino
  • Patrizio Mazzone
  • Paolo Della Bella
  • Circ Arrhythm Electrophysiol.2020 Jul;doi: 10.1161/CIRCEP.119.008307.Epub 2020-07-12.

Circular RNA 406961はILF2と相互作用し、STAT3/JNK経路の活性化を介してヒト気管支上皮細胞におけるPM誘導性炎症反応を調節する

Circular RNA 406961 interacts with ILF2 to regulate PM-induced inflammatory responses in human bronchial epithelial cells via activation of STAT3/JNK pathways.
  • Yangyang Jia
  • Xin Li
  • Aruo Nan
  • Nan Zhang
  • Lijian Chen
  • Hanyu Zhou
  • Han Zhang
  • Miaoyun Qiu
  • Jialu Zhu
  • Yihui Ling
  • Yiguo Jiang
  • Environ Int.2020 Aug;141:105755. S0160-4120(19)33945-5. doi: 10.1016/j.envint.2020.105755.Epub 2020-05-07.

研究のための角膜提供と移植のための角膜提供。フランスの大学病院における受け入れ率の1年間のプロスペクティブ研究

Corneal donation for research versus for transplantation: A-year prospective study of acceptance rates in a French University Hospital.
  • Thibaud Garcin
  • Jean Loup Pugniet
  • Thierry Peyragrosse
  • Francoise Rogues
  • Sophie Acquart
  • Fabrice Cognasse
  • Gilles Thuret
  • Philippe Gain
  • PLoS ONE.2020;15(5):e0233392. PONE-D-19-35417. doi: 10.1371/journal.pone.0233392.Epub 2020-05-21.

1 型糖尿病の青年および若年成人における血糖コントロールに対する持続的血糖モニタリングの効果。無作為化臨床試験

Effect of Continuous Glucose Monitoring on Glycemic Control in Adolescents and Young Adults With Type 1 Diabetes: A Randomized Clinical Trial.
  • Lori M Laffel
  • Lauren G Kanapka
  • Roy W Beck
  • Katherine Bergamo
  • Mark A Clements
  • Amy Criego
  • Daniel J DeSalvo
  • Robin Goland
  • Korey Hood
  • David Liljenquist
  • Laurel H Messer
  • Roshanak Monzavi
  • Thomas J Mouse
  • Priya Prahalad
  • Jennifer Sherr
  • Jill H Simmons
  • R Paul Wadwa
  • Ruth S Weinstock
  • Steven M Willi
  • Kellee M Miller
  • JAMA.2020 06;323(23):2388-2396. 2767160. doi: 10.1001/jama.2020.6940.

デュシェンヌ型筋ジストロフィーを持つ小児におけるrAAVrh74.MHCK7.マイクロジストロフィンの全身投与の評価。非ランダム化対照試験

Assessment of Systemic Delivery of rAAVrh74.MHCK7.micro-dystrophin in Children With Duchenne Muscular Dystrophy: A Nonrandomized Controlled Trial.
  • Jerry R Mendell
  • Zarife Sahenk
  • Kelly Lehman
  • Carrie Nease
  • Linda P Lowes
  • Natalie F Miller
  • Megan A Iammarino
  • Lindsay N Alfano
  • Amanda Nicholl
  • Samiah Al-Zaidy
  • Sarah Lewis
  • Kathleen Church
  • Richard Shell
  • Linda H Cripe
  • Rachael A Potter
  • Danielle A Griffin
  • Eric Pozsgai
  • Ashish Dugar
  • Mark Hogan
  • Louise R Rodino-Klapac
  • JAMA Neurol.2020 Jun;2767086. doi: 10.1001/jamaneurol.2020.1484.Epub 2020-06-15.

ナイアシンアミドの最適化された低pH製剤は、ヒト表皮ケラチノサイトにおけるオートファジーマーカーATG5遺伝子の発現とタンパク質レベルの誘導を増強する

Optimized low pH formulation of niacinamide enhances induction of autophagy marker ATG5 gene expression and protein levels in human epidermal keratinocytes.
  • J E Oblong
  • Y M DeAngelis
  • B B Jarrold
  • J C Bierman
  • H A Rovito
  • L Vires
  • B Fang
  • T Laughlin
  • W Zhao
  • S M Hartman
  • R Kainkaryam
  • R Adams
  • J D Sherrill
  • T Hakozaki
  • J Eur Acad Dermatol Venereol.2020 Jun;34 Suppl 3:3-11. doi: 10.1111/jdv.16582.

12N-置換マトリノール誘導体は肝細胞のステラート細胞におけるインテグリン/FAK/PI3K/Akt経路の抑制を介して線維性遺伝子の発現を抑制した

12N-Substituted Matrinol Derivatives Inhibited the Expression of Fibrogenic Genes via Repressing Integrin/FAK/PI3K/Akt Pathway in Hepatic Stellate Cells.
  • Yunyang Bao
  • Yudong Pang
  • Sheng Tang
  • Tianyun Niu
  • Zhihao Guo
  • Hongwei He
  • Yinghong Li
  • Danqing Song
  • Molecules.2019 Oct;24(20). E3748. doi: 10.3390/molecules24203748.Epub 2019-10-17.

NOX2とミトコンドリア由来の活性酸素によるカタラーゼS-グルタチオン化はマウスとヒト好中球の生存に悪影響を及ぼす

Catalase S-Glutathionylation by NOX2 and Mitochondrial-Derived ROS Adversely Affects Mice and Human Neutrophil Survival.
  • Sheela Nagarkoti
  • Megha Dubey
  • Samreen Sadaf
  • Deepika Awasthi
  • Tulika Chandra
  • Kumaravelu Jagavelu
  • Sachin Kumar
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  • Inflammation.2019 Dec;42(6):2286-2296. 10.1007/s10753-019-01093-z. doi: 10.1007/s10753-019-01093-z.

COVID-19に対するインターフェロンβ-1aの皮下投与。非対照プロスペクティブ試験

Subcutaneous administration of interferon beta-1a for COVID-19: A non-controlled prospective trial.
  • Farzaneh Dastan
  • Seyed Alireza Nadji
  • Ali Saffaei
  • Majid Marjani
  • Afshin Moniri
  • Hamidreza Jamaati
  • Seyed MohammadReza Hashemian
  • Parvaneh Baghaei
  • Atefeh Abedini
  • Mohammad Varahram
  • Sahar Yousefian
  • Payam Tabarsi
  • Int. Immunopharmacol..2020 Aug;85:106688. S1567-5769(20)31289-3. doi: 10.1016/j.intimp.2020.106688.Epub 2020-06-07.

PROLAPSE：外部ビーム再照射による局所前立腺癌再発サルベージ治療に関する調査：イタリア放射線治療・臨床腫瘍学会（AIRO）の結果

PROLAPSE: survey about local prostate cancer relapse salvage treatment with external beam re-irradiation: results of the Italian Association of Radiotherapy and Clinical Oncology (AIRO).
  • Dario Zerini
  • Barbara Alicja Jereczek-Fossa
  • Antonella Ciabattoni
  • Alessandra Mirri
  • Filippo Bertoni
  • Sergio Fersino
  • Giuseppe D'Agostino
  • Frank Lohr
  • Gianluca Mortellaro
  • Luca Triggiani
  • Giulia Marvaso
  • Matteo Pepa
  • Francesco Cuccia
  • Filippo Alongi
  • J. Cancer Res. Clin. Oncol..2020 Jun;10.1007/s00432-020-03297-5. doi: 10.1007/s00432-020-03297-5.Epub 2020-06-24.

根治的前立腺切除術前の局所転移を除外するためのGa標識前立腺特異膜抗原PET/CTとマルチパラメトリックMRIの比較

A comparison between Ga-labeled prostate-specific membrane antigen-PET/CT and multiparametric MRI for excluding regional metastases prior to radical prostatectomy.
  • Michael Frumer
  • Nadav Milk
  • Gal Rinott Mizrahi
  • Sergiu Bistritzky
  • Itay Sternberg
  • Ilan Leibovitch
  • Yoram Dekel
  • Gilad E Amiel
  • Amnon Zisman
  • Jack Baniel
  • Miki Haifler
  • Jonathan Gal
  • Azik Hoffman
  • Itay Sagy
  • Barak Rosenzweig
  • Rennen Haramaty
  • Shay Golan
  • Abdom Radiol (NY).2020 Jul;10.1007/s00261-020-02640-1. doi: 10.1007/s00261-020-02640-1.Epub 2020-07-15.

AKAP-PKA 相互作用の破壊は、ヒト気道平滑筋における増殖マーカーの付随的な増加と高収縮性を誘導する

Disruption of AKAP-PKA Interaction Induces Hypercontractility With Concomitant Increase in Proliferation Markers in Human Airway Smooth Muscle.
  • Hoeke A Baarsma
  • Bing Han
  • Wilfred J Poppinga
  • Saskia Driessen
  • Carolina R S Elzinga
  • Andrew J Halayko
  • Herman Meurs
  • Harm Maarsingh
  • Martina Schmidt
  • Front Cell Dev Biol.2020;8:165. doi: 10.3389/fcell.2020.00165.Epub 2020-04-09.

慢性心不全は、イヌの中庭細胞におけるアデノシンの負のクロノトロピー作用を、A1R刺激とGIRK介在Iを介して増加させる

Chronic heart failure increases negative chronotropic effects of adenosine in canine sinoatrial cells via A1R stimulation and GIRK-mediated I.
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  • Ingrid M Bonilla
  • Stephen Baine
  • Patric Glynn
  • Sanjay Kumar
  • Karsten Schober
  • Kent Mowrey
  • Raul Weiss
  • Nam Y Lee
  • Peter J Mohler
  • Sandor Györke
  • Thomas J Hund
  • Vadim V Fedorov
  • Cynthia A Carnes
  • Life Sci..2020 Jan;240:117068. S0024-3205(19)30995-6. doi: 10.1016/j.lfs.2019.117068.Epub 2019-11-18.

伝統医学で使用される植物であるCymbopogon nardusの精油の化学組成、抗酸化作用、抗炎症作用、抗増殖作用

Chemical composition, antioxidant, anti-inflammatory and antiproliferative activities of the essential oil of Cymbopogon nardus, a plant used in traditional medicine.
  • Bagora Bayala
  • Ahmed Y Coulibaly
  • Florencia W Djigma
  • Bolni Marius Nagalo
  • Silvère Baron
  • Gilles Figueredo
  • Jean-Marc A Lobaccaro
  • Jacques Simpore
  • Biomol Concepts.2020 Apr;11(1):86-96. /j/bmc.2020.11.issue-1/bmc-2020-0007/bmc-2020-0007.xml. doi: 10.1515/bmc-2020-0007.Epub 2020-04-15.

難治性気胸、気管支瘻を伴う気胸、術後の空気漏れに対する内視鏡的気管支閉塞術の臨床的評価

The Clinical Evaluation of Endoscopic Bronchial Occlusion with an Endobronchial Watanabe Spigot for the Management of Intractable Pneumothorax, Pyothorax with Bronchial Fistula, and Postoperative Air Leakage.
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  • Gen-Ichi Tanaka
  • Chikara Fukuyama
  • Ritsuya Shiiba
  • Atsushi Yamanaka
  • Kiichiro Beppu
  • Intern. Med..2020 Apr;doi: 10.2169/internalmedicine.3900-19.Epub 2020-04-30.

Tracheobronchial Slough, a Potential Pathology in Endotracheal Tube Obstruction in Patients With Coronavirus Disease 2019 (COVID-19) in Intensive Care Setting

Tracheobronchial Slough, a Potential Pathology in Endotracheal Tube Obstruction in Patients With Coronavirus Disease 2019 (COVID-19) in the Intensive Care Setting.
  • Jerry A Rubano
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  • Daniel N Rutigliano
  • Apostolos K Tassiopoulos
  • James E Davis
  • Tazeen Beg
  • Shaji Poovathoor
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  • Sahar Ahmad
  • Randeep S Jawa
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  • Ann. Surg..2020 May;doi: 10.1097/SLA.0000000000004031.Epub 2020-05-20.

前立腺肥大症による下部尿路症状の治療マッピング-ドイツの前立腺センターの運営団体の分析

[Treatment mapping of lower urinary tract symptoms due to benign prostatic hyperplasia-an analysis of the Governing Body of German Prostate Centers].
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  • H Baur
  • F Oberpenning
  • M Reimann
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  • B Planz
  • E Gronau
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  • A Heidenreich
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  • Urologe A.2020 Apr;10.1007/s00120-020-01192-y. doi: 10.1007/s00120-020-01192-y.Epub 2020-04-09.

臭化ピリドスチグミンの前処理は、急性ジイソプロピルフルオロリン酸中毒のラットモデルにおける発作行動および24時間生存率に影響を与えない

Pretreatment with pyridostigmine bromide has no effect on seizure behavior or 24 hour survival in the rat model of acute diisopropylfluorophosphate intoxication.
  • Donald A Bruun
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  • Neurotoxicology.2019 07;73:81-84. S0161-813X(19)30018-X. doi: 10.1016/j.neuro.2019.03.001.Epub 2019-03-07.

マウスのクエン酸ナトリウム依存性トランスポーターSLC13A5を破壊すると、海馬における脳内クエン酸塩濃度と神経回路網の興奮性に変化が生じる

Disruption of the sodium-dependent citrate transporter SLC13A5 in mice causes alterations in brain citrate levels and neuronal network excitability in the hippocampus.
  • Christine Henke
  • Kathrin Töllner
  • R Maarten van Dijk
  • Nina Miljanovic
  • Thekla Cordes
  • Friederike Twele
  • Sonja Bröer
  • Vanessa Ziesak
  • Marco Rohde
  • Stefanie M Hauck
  • Charlotte Vogel
  • Lisa Welzel
  • Tina Schumann
  • Diana M Willmes
  • Anica Kurzbach
  • Nermeen N El-Agroudy
  • Stefan R Bornstein
  • Susanne A Schneider
  • Jens Jordan
  • Heidrun Potschka
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  • Andreas L Birkenfeld
  • Wolfgang Löscher
  • Neurobiol. Dis..2020 Jul;:105018. S0969-9961(20)30293-X. doi: 10.1016/j.nbd.2020.105018.Epub 2020-07-16.

SARS-CoV-2 グアニン-N7 メチルトランスフェラーゼ(nsp14)の構造に基づくバーチャルスクリーニングと分子動力学シミュレーションによるCOVID-19に対する抗ウイルス阻害剤の同定

Structure-based virtual screening and molecular dynamics simulation of SARS-CoV-2 Guanine-N7 methyltransferase (nsp14) for identifying antiviral inhibitors against COVID-19.
  • Chandrabose Selvaraj
  • Dhurvas Chandrasekaran Dinesh
  • Umesh Panwar
  • Rajaram Abhirami
  • Evzen Boura
  • Sanjeev Kumar Singh
  • J. Biomol. Struct. Dyn..2020 Jun;:1-12. doi: 10.1080/07391102.2020.1778535.Epub 2020-06-22.

カモミール（L.）の花の生物活性成分に対する異なるグリーン抽出方法と溶媒の効果

Effect of Different Green Extraction Methods and Solvents on Bioactive Components of Chamomile ( L.) Flowers.
  • Jana Šic Žlabur
  • Ivanka Žutić
  • Sanja Radman
  • Maja Pleša
  • Mladen Brnčić
  • Francisco J Barba
  • Gabriele Rocchetti
  • Luigi Lucini
  • Jose M Lorenzo
  • Rubén Domínguez
  • Suzana Rimac Brnčić
  • Ante Galić
  • Sandra Voća
  • Molecules.2020 Feb;25(4). E810. doi: 10.3390/molecules25040810.Epub 2020-02-13.

タンパク質-タンパク質相互作用の阻害剤としての膜貫通ペプチド。癌細胞を標的とした効率的な戦略とは？

Transmembrane Peptides as Inhibitors of Protein-Protein Interactions: An Efficient Strategy to Target Cancer Cells?
  • Camille Albrecht
  • Aline Appert-Collin
  • Dominique Bagnard
  • Sébastien Blaise
  • Béatrice Romier-Crouzet
  • Roman G Efremov
  • Hervé Sartelet
  • Laurent Duca
  • Pascal Maurice
  • Amar Bennasroune
  • Front Oncol.2020;10:519. doi: 10.3389/fonc.2020.00519.Epub 2020-04-15.

多様な情報源からの組織の統合的リン酸化プロテオミクスプロファイリングを介して心筋線維症のシグナル伝達の摂動をマッピングする

Mapping signalling perturbations in myocardial fibrosis via the integrative phosphoproteomic profiling of tissue from diverse sources.
  • Uros Kuzmanov
  • Erika Yan Wang
  • Rachel Vanderlaan
  • Da Hye Kim
  • Shin-Haw Lee
  • Sina Hadipour-Lakmehsari
  • Hongbo Guo
  • Yimu Zhao
  • Meghan McFadden
  • Parveen Sharma
  • Filio Billia
  • Milica Radisic
  • Anthony Gramolini
  • Andrew Emili
  • Nat Biomed Eng.2020 Jul;10.1038/s41551-020-0585-y. doi: 10.1038/s41551-020-0585-y.Epub 2020-07-13.

シャルコー・マリー・トゥース病型2Dマウスモデルで神経障害を予防するアレル特異的RNA干渉

Allele-specific RNA interference prevents neuropathy in Charcot-Marie-Tooth disease type 2D mouse models.
  • Kathryn H Morelli
  • Laurie B Griffin
  • Nettie K Pyne
  • Lindsay M Wallace
  • Allison M Fowler
  • Stephanie N Oprescu
  • Ryuichi Takase
  • Na Wei
  • Rebecca Meyer-Schuman
  • Dattatreya Mellacheruvu
  • Jacob O Kitzman
  • Samuel G Kocen
  • Timothy J Hines
  • Emily L Spaulding
  • James R Lupski
  • Alexey Nesvizhskii
  • Pedro Mancias
  • Ian J Butler
  • Xiang-Lei Yang
  • Ya-Ming Hou
  • Anthony Antonellis
  • Scott Q Harper
  • Robert W Burgess
  • J. Clin. Invest..2019 12;129(12):5568-5583. 130600. doi: 10.1172/JCI130600.

コクシジウム症に対するワクチンを接種したブロイラーと接種していないブロイラーの性能と糞便微生物相に及ぼすカプセル化されたシンナムアルデヒドとシトラールの効果

Effects of encapsulated cinnamaldehyde and citral on the performance and cecal microbiota of broilers vaccinated or not vaccinated against coccidiosis.
  • Chongwu Yang
  • Yan Martel Kennes
  • Dion Lepp
  • Xianhua Yin
  • Qi Wang
  • Hai Yu
  • Chengbo Yang
  • Joshua Gong
  • Moussa S Diarra
  • Poult. Sci..2020 Feb;99(2):936-948. S0032-5791(19)44771-8. doi: 10.1016/j.psj.2019.10.036.Epub 2019-12-04.

抗生物質の処方に対する全国的な抗菌薬スチュワードシップキャンペーンの影響を評価するための中断時系列分析。中国のプライマリ・ケアにおける典型的な実践

Interrupted Time-Series Analysis to Evaluate the Impact of a National Antimicrobial Stewardship Campaign on Antibiotic Prescribing: A Typical Practice in China's Primary Care.
  • Hui Li
  • Yanhong Gong
  • Jing Han
  • Shengchao Zhang
  • Shanquan Chen
  • Xing Xu
  • Zuxun Lu
  • Xiaoxv Yin
  • Clin. Infect. Dis..2020 Jul;ciaa962. doi: 10.1093/cid/ciaa962.Epub 2020-07-10.

健康な肺を持つ小児における異なるPEEPレベルでの換気内コンプライアンスプロファイルの評価：プロスペクティブ、クロスオーバー研究

Evaluation of the intratidal compliance profile at different PEEP levels in children with healthy lungs: a prospective, crossover study.
  • Ji-Hyun Lee
  • Sang-Hwan Ji
  • Hyung-Chul Lee
  • Young-Eun Jang
  • Eun-Hee Kim
  • Hee-Soo Kim
  • Jin-Tae Kim
  • Br J Anaesth.2020 Jul;S0007-0912(20)30506-7. doi: 10.1016/j.bja.2020.06.046.Epub 2020-07-15.

COVID-19パンデミックが小児泌尿器科医療の生産性、ガイドラインの遵守、プロバイダーのストレスに及ぼす影響についての調査とパネルディスカッション

A survey and panel discussion of the effects of the COVID-19 pandemic on paediatric urological productivity, guideline adherence and provider stress.
  • Fardod O'Kelly
  • Scott Sparks
  • Casey Seideman
  • Patricio Gargollo
  • Candace Granberg
  • Joan Ko
  • Neha Malhotra
  • Sarah Hecht
  • Kelly Swords
  • Courtney Rowe
  • Ben Whittam
  • Anne-Francoise Spinoit
  • Anne Dudley
  • Jonathan Ellison
  • David Chu
  • Jonathan Routh
  • Glenn Cannon
  • Paul Kokorowski
  • Martin Koyle
  • Mesrur Selcuk Silay
  • J Pediatr Urol.2020 Jul;S1477-5131(20)30401-0. doi: 10.1016/j.jpurol.2020.06.024.Epub 2020-07-04.

長期療養施設における適切な抗生物質の処方を改善するための介入：システマティックレビュー

Interventions to improve appropriate antibiotic prescribing in long-term care facilities: a systematic review.
  • Elise Crayton
  • Michelle Richardson
  • Chris Fuller
  • Catherine Smith
  • Sunny Liu
  • Gillian Forbes
  • Niall Anderson
  • Laura Shallcross
  • Susan Michie
  • Andrew Hayward
  • Fabiana Lorencatto
  • BMC Geriatr.2020 Jul;20(1):237. 10.1186/s12877-020-01564-1. doi: 10.1186/s12877-020-01564-1.Epub 2020-07-09.

ブラジル北東部におけるSporothrix brasiliensisによる致死的な肺胞子嚢胞子嚢胞子症

Fatal pulmonary sporotrichosis caused by Sporothrix brasiliensis in Northeast Brazil.
  • Manoella do Monte Alves
  • Eveline Pipolo Milan
  • Walicyranison Plinio da Silva-Rocha
  • Alexandre Soares de Sena da Costa
  • Bruno Araújo Maciel
  • Pedro Henrique Cavalcante Vale
  • Paulo Roberto de Albuquerque
  • Soraia Lopes Lima
  • Analy Salles de Azevedo Melo
  • Anderson Messias Rodrigues
  • Guilherme Maranhão Chaves
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グアテマラにおける高血圧コントロール改善のための多成分プログラムの評価：有効性が実証されたクラスター無作為化試験の試験プロトコール

Evaluating a multicomponent program to improve hypertension control in Guatemala: study protocol for an effectiveness-implementation cluster randomized trial.
  • Alejandra Paniagua-Avila
  • Meredith P Fort
  • Russell E Glasgow
  • Pablo Gulayin
  • Diego Hernández-Galdamez
  • Kristyne Mansilla
  • Eduardo Palacios
  • Ana Lucia Peralta
  • Dina Roche
  • Adolfo Rubinstein
  • Jiang He
  • Manuel Ramirez-Zea
  • Vilma Irazola
  • Trials.2020 Jun;21(1):509. 10.1186/s13063-020-04345-8. doi: 10.1186/s13063-020-04345-8.Epub 2020-06-09.

ブラジルのニンニクとタマネギの作物土壌に由来するトリコデルマと新種2種の記述。Trichoderma azevedoiとTrichoderma peberdyi

Trichoderma from Brazilian garlic and onion crop soils and description of two new species: Trichoderma azevedoi and Trichoderma peberdyi.
  • Peter W Inglis
  • Sueli C M Mello
  • Irene Martins
  • João B T Silva
  • Kamilla Macêdo
  • Daniel N Sifuentes
  • M Cleria Valadares-Inglis
  • PLoS ONE.2020;15(3):e0228485. PONE-D-19-21858. doi: 10.1371/journal.pone.0228485.Epub 2020-03-04.

直接経口抗凝固薬に対する開業医の認識と出産可能年齢の女性における性器出血のリスクに関する記述的研究

Descriptive study of the general practitioners' perception of direct oral anticoagulants and the risk of genital bleeding in women of childbearing age.
  • E Paoletti
  • S Rezkallah
  • S El Harake
  • M Castelli
  • Y Benresdouane
  • D Brunet
  • P Suchon
  • P Morange
  • G Sarlon-Bartoli
  • J Med Vasc.2020 Jul;45(4):198-209. S2542-4513(20)30266-2. doi: 10.1016/j.jdmv.2020.04.012.Epub 2020-05-27.

COVID-19発生中の長期療養施設における医療機器からの重症急性呼吸器症候群コロナウイルス2（SARS-CoV-2）の環境検出

Environmental Detection of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) from Medical Equipment in Long-Term Care Facilities undergoing COVID-19 Outbreaks.
  • Atiba Nelson
  • Jennifer Kassimatis
  • Jay Estoque
  • Cicely Yang
  • Geoff McKee
  • Elizabeth Bryce
  • Linda Hoang
  • Patricia Daly
  • Mark Lysyshyn
  • Althea S Hayden
  • John Harding
  • Suni Boraston
  • Meena Dawar
  • Michael Schwandt
  • Am J Infect Control.2020 Jul;S0196-6553(20)30643-X. doi: 10.1016/j.ajic.2020.07.001.Epub 2020-07-06.

内皮依存性高分極の障害は、初期のメタボリックチャレンジ中の内皮機能障害の根底にある：活性酸素生成の増加とNO機能への可能性のある干渉

Impaired Endothelium-Dependent Hyperpolarization Underlies Endothelial Dysfunction during Early Metabolic Challenge: Increased ROS Generation and Possible Interference with NO Function.
  • Rana Alaaeddine
  • Mohammed A W Elkhatib
  • Ali Mroueh
  • Hosny Fouad
  • Evan I Saad
  • Marwan E El-Sabban
  • Frances Plane
  • Ahmed F El-Yazbi
  • J. Pharmacol. Exp. Ther..2019 12;371(3):567-582. jpet.119.262048. doi: 10.1124/jpet.119.262048.Epub 2019-09-11.

化合物特異的安定同位体分析を含む複数のラインオブエヴィデンスアプローチによるフィールド堆積物中のPCBの発生源と微生物分解の追跡

Tracing the sources and microbial degradation of PCBs in field sediments by a multiple-line-of-evidence approach including compound-specific stable isotope analysis.
  • Chenchen Huang
  • Yanhong Zeng
  • Xiaojun Luo
  • Zihe Ren
  • Qihong Lu
  • Yankuan Tian
  • Shutao Gao
  • Shanquan Wang
  • Stuart Harrad
  • Bixian Mai
  • Water Res..2020 May;182:115977. S0043-1354(20)30514-5. doi: 10.1016/j.watres.2020.115977.Epub 2020-05-27.

コロンビアにおける抗生物質処方のパターン。コロンビアにおける抗生物質処方のパターン：首都とコミューンの間に違いはあるか？

Patterns of Antibiotic Prescription in Colombia: Are There Differences between Capital Cities and Municipalities?
  • Jorge Enrique Machado-Alba
  • Luis Fernando Valladales-Restrepo
  • Andrés Gaviria-Mendoza
  • Manuel Enrique Machado-Duque
  • Albert Figueras
  • Antibiotics (Basel).2020 Jul;9(7). E389. doi: 10.3390/antibiotics9070389.Epub 2020-07-08.

ラットにおける進行性ドキソルビシン誘発性腎毒性の改善剤としてのメロキシカム（シクロオイゲナーゼ2阻害剤）対ビタミンD3（コレカルシフェロール）の効果

Effect of meloxicam (cyclooygenase-2 inhibitor) versus vitamin D3 (cholecalciferol) as ameliorating agents of progressive doxorubicin-induced nephrotoxicity in rats.
  • Dalia Mahmoud Abdelmonem Elsherbini
  • Hasnaa Ali Ebrahim
  • Anat Cell Biol.2020 Jun;53(2):169-182. acb.19.231. doi: 10.5115/acb.19.231.

胃バイパス術とスリーブ胃切除術。スウェーデン、ノルウェー、オランダの国家品質登録機関による47,101例の一次手術の患者選択と短期成績

Gastric Bypass Versus Sleeve Gastrectomy: Patient Selection and Short-term Outcome of 47,101 Primary Operations From the Swedish, Norwegian, and Dutch National Quality Registries.
  • Youri Q M Poelemeijer
  • Ronald S L Liem
  • Villy Våge
  • Tom Mala
  • Magnus Sundbom
  • Johan Ottosson
  • Simon W Nienhuijs
  • Ann. Surg..2020 Aug;272(2):326-333. 00000658-202008000-00066. doi: 10.1097/SLA.0000000000003279.

メデトミジンおよびブトルファノールとの共投与である筋肉内投与のバチノキサン（MK-467）の、イヌにおけるケタミン静脈内投与の心肺および麻酔効果に対する効果

Effects of intramuscular vatinoxan (MK-467), co-administered with medetomidine and butorphanol, on cardiopulmonary and anaesthetic effects of intravenous ketamine in dogs.
  • Heta Turunen
  • Marja Raekallio
  • Juhana Honkavaara
  • Johanna Jaakkola
  • Mika Scheinin
  • Sofia Männikkö
  • Heidi Hautajärvi
  • Rachel Bennett
  • Outi Vainio
  • Vet Anaesth Analg.2020 Jun;S1467-2987(20)30105-7. doi: 10.1016/j.vaa.2020.05.008.Epub 2020-06-11.

デコキネートナノリポソームの最適条件とブロイラーにおけるジクラズリル耐性Eimeria tenella感染症に対する抗菌効果の評価

Evaluation of optimum conditions for decoquinate nanoliposomes and their anticoccidial efficacy against diclazuril-resistant Eimeria tenella infections in broilers.
  • Ruonan Bo
  • Xingru Dai
  • Jie Huang
  • Simin Wei
  • Mingjiang Liu
  • Jingui Li
  • Vet. Parasitol..2020 Jul;283:109186. S0304-4017(20)30166-7. doi: 10.1016/j.vetpar.2020.109186.Epub 2020-07-16.

オーストラリアおよびニュージーランドにおけるコロナウイルス疾患の重症・急性期未病の入院患者に対する栄養管理2019（COVID-19）

Nutrition management for critically and acutely unwell hospitalised patients with coronavirus disease 2019 (COVID-19) in Australia and New Zealand.
  • Lee-Anne S Chapple
  • Kate Fetterplace
  • Varsha Asrani
  • Aidan Burrell
  • Allen C Cheng
  • Peter Collins
  • Ra'eesa Doola
  • Suzie Ferrie
  • Andrea P Marshall
  • Emma J Ridley
  • Aust Crit Care.2020 Jul;S1036-7314(20)30244-7. doi: 10.1016/j.aucc.2020.06.002.Epub 2020-07-02.

菌体外小胞には、H. bakeriとT. murisの異なるmicroRNAファミリーとsmall RNAが含まれており、これらは宿主のニッチで異なる機能を支えている可能性がある

Extracellular vesicles from Heligmosomoides bakeri and Trichuris muris contain distinct microRNA families and small RNAs that could underpin different functions in the host.
  • Ruby White
  • Sujai Kumar
  • Franklin Wang-Ngai Chow
  • Elaine Robertson
  • Kelly S Hayes
  • Richard K Grencis
  • María A Duque-Correa
  • Amy Buck
  • Int. J. Parasitol..2020 Jul;S0020-7519(20)30164-8. doi: 10.1016/j.ijpara.2020.06.002.Epub 2020-07-10.

超音波と結合した植物由来のミリセチン分子の乳がんに対する金ナノ粒子合成への利用

Utilization of plant-derived Myricetin molecule coupled with ultrasound for the synthesis of gold nanoparticles against breast cancer.
  • Uma Priya Mohan
  • Bhaskaran Sriram
  • Theivendren Panneerselvam
  • Sankarganesh Devaraj
  • Davoodbasha MubarakAli
  • Pavadai Parasuraman
  • Ponnusamy Palanisamy
  • Adhvitha Premanand
  • Sankarganesh Arunachalam
  • Selvaraj Kunjiappan
  • Naunyn Schmiedebergs Arch. Pharmacol..2020 May;10.1007/s00210-020-01874-6. doi: 10.1007/s00210-020-01874-6.Epub 2020-05-28.

呼吸に焦点を当てたヨガは単極性および双極性うつ病のための補強として。無作為化対照試験。呼吸に焦点を当てたヨガは、単極性および双極性抑うつのための補強法として有効である。ランダム対照試験

Breathing-focused Yoga as Augmentation for Unipolar and Bipolar Depression: A Randomized Controlled Trial: Le yoga axé sur la respiration comme traitement d'appoint pour la dépression unipolaire et bipolaire: Un essai randomisé contrôlé.
  • Arun V Ravindran
  • Martha S McKay
  • Tricia da Silva
  • Claudia Tindall
  • Tiffany Garfinkel
  • Angela Paric
  • Lakshmi Ravindran
  • Can J Psychiatry.2020 Jul;:706743720940535. doi: 10.1177/0706743720940535.Epub 2020-07-17.

最小肝性脳症を伴う肝硬変患者における運動機能と認知機能

Motor and Cognitive Performance in Patients with Liver Cirrhosis with Minimal Hepatic Encephalopathy.
  • Constanza San Martín-Valenzuela
  • Aroa Borras-Barrachina
  • Juan-José Gallego
  • Amparo Urios
  • Víctor Mestre-Salvador
  • Patricia Correa-Ghisays
  • María-Pilar Ballester
  • Desamparados Escudero-García
  • Joan Tosca
  • Cristina Montón
  • María-Pilar Ríos
  • Elena Kosenko
  • Vicente Felipo
  • Rafael Tabares-Seisdedos
  • Gabriel Selva-Vera
  • Carmina Montoliu
  • J Clin Med.2020 Jul;9(7). E2154. doi: 10.3390/jcm9072154.Epub 2020-07-08.

TASK-1（弱内向き整流型酸感受性Kチャネル-1のPドメインのタンデム）（K3.1）Kチャネルを遺伝子的にアブレーションすると心房細動が抑制され、電気的リモデリングが抑制される

Genetic Ablation of TASK-1 (Tandem of P Domains in a Weak Inward Rectifying K Channel-Related Acid-Sensitive K Channel-1) (K3.1) K Channels Suppresses Atrial Fibrillation and Prevents Electrical Remodeling.
  • Constanze Schmidt
  • Felix Wiedmann
  • Christoph Beyersdorf
  • Zhihan Zhao
  • Ibrahim El-Battrawy
  • Huan Lan
  • Gabor Szabo
  • Xin Li
  • Siegfried Lang
  • Sevil Korkmaz-Icöz
  • Kleopatra Rapti
  • Andreas Jungmann
  • Antonius Ratte
  • Oliver J Müller
  • Matthias Karck
  • Gunnar Seemann
  • Ibrahim Akin
  • Martin Borggrefe
  • Xiao-Bo Zhou
  • Hugo A Katus
  • Dierk Thomas
  • Circ Arrhythm Electrophysiol.2019 09;12(9):e007465. doi: 10.1161/CIRCEP.119.007465.Epub 2019-09-13.

βアドレナリン作動薬であるラクトパミンは、統合的なストレス応答遺伝子プログラムの一部として、アスパラギン合成酵素の骨格筋発現を増加させます

The Beta-adrenergic agonist, Ractopamine, increases skeletal muscle expression of Asparagine Synthetase as part of an integrated stress response gene program.
  • David Brown
  • Kevin Ryan
  • Zoe Daniel
  • Molebeledi Mareko
  • Richard Talbot
  • Joanna Moreton
  • Tom C B Giles
  • Richard Emes
  • Charlie Hodgman
  • Tim Parr
  • John M Brameld
  • Sci Rep.2018 10;8(1):15915. 10.1038/s41598-018-34315-9. doi: 10.1038/s41598-018-34315-9.Epub 2018-10-29.

ストレプトマイセス（Streptomyces）のポリペプチドの細胞内トポロジーを網羅的に掲載している

Comprehensive subcellular topologies of polypeptides in Streptomyces.
  • Konstantinos C Tsolis
  • Evridiki-Pandora Tsare
  • Georgia Orfanoudaki
  • Tobias Busche
  • Katerina Kanaki
  • Reshmi Ramakrishnan
  • Frederic Rousseau
  • Joost Schymkowitz
  • Christian Rückert
  • Jörn Kalinowski
  • Jozef Anné
  • Spyridoula Karamanou
  • Maria I Klapa
  • Anastassios Economou
  • Microb. Cell Fact..2018 Mar;17(1):43. 10.1186/s12934-018-0892-0. doi: 10.1186/s12934-018-0892-0.Epub 2018-03-15.

ワラビシダ植物のptesculentoside, caudatoside, ptaquilosideおよび対応するプテロシンの高速LC-MS定量

Fast LC-MS quantification of ptesculentoside, caudatoside, ptaquiloside and corresponding pterosins in bracken ferns.
  • Vaidotas Kisielius
  • Dan Nybro Lindqvist
  • Mikkel Boas Thygesen
  • Michael Rodamer
  • Hans Christian Bruun Hansen
  • Lars Holm Rasmussen
  • J. Chromatogr. B Analyt. Technol. Biomed. Life Sci..2020 Feb;1138:121966. S1570-0232(19)31442-4. doi: 10.1016/j.jchromb.2019.121966.Epub 2020-01-03.

ガスクロマトグラフィー-質量分析-オルファクトメトリーと臭気活性値を用いたZanthoxylum armatum DC Prodr.果皮油中の強力な臭気成分の特性評価（英文

Characterization of the potent odorants in Zanthoxylum armatum DC Prodr. pericarp oil by application of gas chromatography-mass spectrometry-olfactometry and odor activity value.
  • Yuping Liu
  • Qingru Li
  • Wenxi Yang
  • Baoguo Sun
  • Ying Zhou
  • Yang Zheng
  • Mingquan Huang
  • Wenjie Yang
  • Food Chem.2020 Jul;319:126564. S0308-8146(20)30426-X. doi: 10.1016/j.foodchem.2020.126564.Epub 2020-03-04.

中枢神経系のミクログリアを研究するための新しいHexbベースのツール

Novel Hexb-based tools for studying microglia in the CNS.
  • Takahiro Masuda
  • Lukas Amann
  • Roman Sankowski
  • Ori Staszewski
  • Maximilian Lenz
  • Paolo D Errico
  • Nicolas Snaidero
  • Marta Joana Costa Jordão
  • Chotima Böttcher
  • Katrin Kierdorf
  • Steffen Jung
  • Josef Priller
  • Thomas Misgeld
  • Andreas Vlachos
  • Melanie Meyer Luehmann
  • Klaus-Peter Knobeloch
  • Marco Prinz
  • Nat. Immunol..2020 07;21(7):802-815. 10.1038/s41590-020-0707-4. doi: 10.1038/s41590-020-0707-4.Epub 2020-06-15.

WHO国際家族分類の枠組みとアプローチを用いたCOVID-19患者のリハビリテーションのプロトコルに関する専門家のコンセンサス

Expert consensus on protocol of rehabilitation for COVID-19 patients using framework and approaches of WHO International Family Classifications.
  • Bin Zeng
  • Di Chen
  • Zhuoying Qiu
  • Minsheng Zhang
  • Guoxiang Wang
  • Jianye Wang
  • Pulin Yu
  • Xianguang Wu
  • Bingchen An
  • Dingqun Bai
  • Zhuoming Chen
  • Jingyuan Deng
  • Qi Guo
  • Chengqi He
  • Xiquan Hu
  • Chongxia Huang
  • Qiuchen Huang
  • Xuming Huang
  • Zhen Huang
  • Xinping Li
  • Zhongming Liang
  • Gang Liu
  • Peng Liu
  • Chao Ma
  • Hongzhuo Ma
  • Zhongxiang Mi
  • Cuihuan Pan
  • Xiue Shi
  • Hongwei Sun
  • Jianing Xi
  • Xiaofei Xiao
  • Tao Xu
  • Wuhua Xu
  • Jian Yang
  • Shaohua Yang
  • Wanzhang Yang
  • Xiangming Ye
  • Xiaoping Yun
  • Aiming Zhang
  • Chong Zhang
  • Pande Zhang
  • Qiaojun Zhang
  • Mingming Zhao
  • Jiejiao Zhao
  • Aging Med (Milton).2020 Jun;3(2):82-94. AGM212120. doi: 10.1002/agm2.12120.Epub 2020-07-06.

安定型虚血性心疾患における血管拡張ストレス CMR と全死亡率．大規模なレトロスペクティブレジストリー

Vasodilator Stress CMR and All-Cause Mortality in Stable Ischemic Heart Disease: A Large Retrospective Registry.
  • Victor Marcos-Garces
  • Jose Gavara
  • Jose V Monmeneu
  • Maria P Lopez-Lereu
  • Maria J Bosch
  • Pilar Merlos
  • Nerea Perez
  • Cesar Rios-Navarro
  • Elena De Dios
  • Clara Bonanad
  • Paolo Racugno
  • Alejandro Bellver Navarro
  • Bruno Ventura Perez
  • Jose Aguilar Botella
  • Silvia Ventura
  • Luis Mainar
  • Joaquim Canoves
  • Mauricio Pellicer
  • David Moratal
  • Gema Miñana
  • Julio Nuñez
  • Francisco J Chorro
  • Vicente Bodi
  • JACC Cardiovasc Imaging.2020 Jul;S1936-878X(20)30253-9. doi: 10.1016/j.jcmg.2020.02.027.Epub 2020-07-10.

に訂正します。ニコチンアミドN-メチルトランスフェラーゼのダウンレギュレーションは、Wnt/β-カテニン経路を介して食道扁平上皮癌の遊走および上皮間葉転移を阻害する

Correction to: Downregulation of nicotinamide N-methyltransferase inhibits migration and epithelial-mesenchymal transition of esophageal squamous cell carcinoma via Wnt/β-catenin pathway.
  • Yanyan Cui
  • Luyu Zhang
  • Wenjie Wang
  • Shanshan Ma
  • Hongtao Liu
  • Xingxing Zang
  • Yanting Zhang
  • Fangxia Guan
  • Mol. Cell. Biochem..2020 Jul;10.1007/s11010-020-03829-0. doi: 10.1007/s11010-020-03829-0.Epub 2020-07-18.

光照射リボフラビン-アミノフィリン系を用いたアミノ機能化グラフェン量子ドットの蛍光消光に基づくアミノフィリンの定量

Determination of aminophylline based on fluorescence quenching of amino-functionalized graphene quantum dots induced by photoilluminated riboflavin-aminophylline system.
  • Meijuan Wang
  • Bowen Tian
  • Yuanyuan Xue
  • Rui Li
  • Tingting Zhai
  • Liang Tan
  • Spectrochim Acta A Mol Biomol Spectrosc.2020 Jul;235:118306. S1386-1425(20)30284-5. doi: 10.1016/j.saa.2020.118306.Epub 2020-03-25.

重度の下顎骨再置換術後の完全義歯作製には2段階印象法は必須か？咀嚼、患者満足度、調整に関する無作為化試験

Is a two-step impression mandatory for complete denture fabrication on the severely resorbed mandible? A randomized trial on mastication, patient satisfaction and adjustments.
  • Ivo S Albuquerque
  • Karina M Freitas-Pontes
  • Raphael F de Souza
  • Wagner A Negreiros
  • Marcelo B Ramos
  • Raniel F Peixoto
  • Rômulo R Regis
  • J Dent.2020 May;:103357. S0300-5712(20)30099-3. doi: 10.1016/j.jdent.2020.103357.Epub 2020-05-08.

アミロイドβオリゴマーの構造と毒性の関係を研究するための研究ツールとしての合理的に設計された抗体

Rationally Designed Antibodies as Research Tools to Study the Structure-Toxicity Relationship of Amyloid-β Oligomers.
  • Ryan Limbocker
  • Benedetta Mannini
  • Rodrigo Cataldi
  • Shianne Chhangur
  • Aidan K Wright
  • Ryan P Kreiser
  • J Alex Albright
  • Sean Chia
  • Johnny Habchi
  • Pietro Sormanni
  • Janet R Kumita
  • Francesco S Ruggeri
  • Christopher M Dobson
  • Fabrizio Chiti
  • Francesco A Aprile
  • Michele Vendruscolo
  • Int J Mol Sci.2020 Jun;21(12). E4542. doi: 10.3390/ijms21124542.Epub 2020-06-25.

ロマミ川流域（コンゴ中流域）のシクリッド（Teleostei: Cichliformes）のエラから得られた6種の新種Cichlidogyrus Paperna, 1960 (Platyhelminthes: Monogenea) (Platyhelminthes: Monogenea)

Six new species of Cichlidogyrus Paperna, 1960 (Platyhelminthes: Monogenea) from the gills of cichlids (Teleostei: Cichliformes) from the Lomami River Basin (DRC: Middle Congo).
  • Mare Geraerts
  • Fidel Muterezi Bukinga
  • Maarten P M Vanhove
  • Antoine Pariselle
  • Auguste Chocha Manda
  • Emmanuel Vreven
  • Tine Huyse
  • Tom Artois
  • Parasit Vectors.2020 Apr;13(1):187. 10.1186/s13071-020-3927-4. doi: 10.1186/s13071-020-3927-4.Epub 2020-04-09.

カドミウム誘起酸化ストレスは、コイリンパ球のmiR-216a-PI3K/AKT軸の調節を介してアポトーシスと壊死を促進し、セレンによって拮抗される

Cadmium-induced oxidative stress promotes apoptosis and necrosis through the regulation of the miR-216a-PI3K/AKT axis in common carp lymphocytes and antagonized by selenium.
  • Jiaqi Zhang
  • Shufang Zheng
  • Shengchen Wang
  • Qingqing Liu
  • Shiwen Xu
  • Chemosphere.2020 Jun;258:127341. S0045-6535(20)31534-4. doi: 10.1016/j.chemosphere.2020.127341.Epub 2020-06-11.

骨髄性悪性腫瘍のハイリスク患者における骨髄芽腫性コンディショニングと同種造血幹細胞移植を併用したデシタビン誘導療法は、感染症合併症の発生率が高いことと関連している

Decitabine induction with myeloablative conditioning and allogeneic hematopoietic stem cell transplantation in high-risk patients with myeloid malignancies is associated with a high rate of infectious complications.
  • Christopher R D'Angelo
  • Aric Hall
  • Kaitlin M Woo
  • KyungMann Kim
  • Walter Longo
  • Peiman Hematti
  • Natalie Callander
  • Vaishalee P Kenkre
  • Ryan Mattison
  • Mark Juckett
  • Leuk. Res..2020 Jul;96:106419. S0145-2126(20)30124-7. doi: 10.1016/j.leukres.2020.106419.Epub 2020-07-08.

3-(トリメトキシシリル)プロピルメタクリレートで機能化したAg NPs-トリプトファンナノ複合体を用いた環境水試料からの水銀イオンの比色検出

Colorimetric detection of mercury ions from environmental water sample by using 3-(Trimethoxysilyl)propyl methacrylate functionalized Ag NPs-tryptophan nanoconjugate.
  • S Balasurya
  • Asad Syed
  • Ajith M Thomas
  • Najat Marraiki
  • Sarah Al-Rashed
  • Abdallah M Elgorban
  • Lija L Raju
  • Arunava Das
  • S Sudheer Khan
  • J. Photochem. Photobiol. B, Biol..2020 Jun;207:111888. S1011-1344(20)30337-7. doi: 10.1016/j.jphotobiol.2020.111888.Epub 2020-04-30.

エジプトの乳牛における乳房炎の有病率と細菌病因、不顕性乳房炎と授乳期がSCCに及ぼす影響に関する研究

Study on prevalence and bacterial etiology of mastitis, and effects of subclinical mastitis and stage of lactation on SCC in dairy goats in Egypt.
  • Hany A Hussein
  • Mohammed T Fouad
  • Khaled A Abd El-Razik
  • Amal M Abo El-Maaty
  • C D'Ambrosio
  • A Scaloni
  • A M Gomaa
  • Trop Anim Health Prod.2020 Jun;10.1007/s11250-020-02331-5. doi: 10.1007/s11250-020-02331-5.Epub 2020-06-24.

胃癌患者が遠位胃切除術を受ける場合、Billroth I再建が適用できない場合、Roux-en-Y再建とBillroth-II再建のどちらが好ましいか？メタアナリシス

Is Roux-en-Y or Billroth-II reconstruction the preferred choice for gastric cancer patients undergoing distal gastrectomy when Billroth I reconstruction is not applicable? A meta-analysis.
  • Lirong He
  • Yajie Zhao
  • Medicine (Baltimore).2019 Nov;98(48):e17093. 00005792-201911290-00001. doi: 10.1097/MD.0000000000017093.

リストアップ時の鉄代謝不均衡は肝移植後の全死亡率と感染症死亡率を増加させる

Iron metabolism imbalance at the time of listing increases overall and infectious mortality after liver transplantation.
  • Elodie Fallet
  • Michel Rayar
  • Amandine Landrieux
  • Christophe Camus
  • Pauline Houssel-Debry
  • Caroline Jezequel
  • Ludivine Legros
  • Thomas Uguen
  • Martine Ropert-Bouchet
  • Karim Boudjema
  • Dominique Guyader
  • Edouard Bardou-Jacquet
  • World J. Gastroenterol..2020 Apr;26(16):1938-1949. doi: 10.3748/wjg.v26.i16.1938.

染色体を用いたメダカのゲノム配列, 塩分適応研究のための小型水槽魚モデル

Genome Sequence of the Euryhaline Javafish Medaka, : A Small Aquarium Fish Model for Studies on Adaptation to Salinity.
  • Yusuke Takehana
  • Margot Zahm
  • Cédric Cabau
  • Christophe Klopp
  • Céline Roques
  • Olivier Bouchez
  • Cécile Donnadieu
  • Celia Barrachina
  • Laurent Journot
  • Mari Kawaguchi
  • Shigeki Yasumasu
  • Satoshi Ansai
  • Kiyoshi Naruse
  • Koji Inoue
  • Chuya Shinzato
  • Manfred Schartl
  • Yann Guiguen
  • Amaury Herpin
  • G3 (Bethesda).2020 03;10(3):907-915. g3.119.400725. doi: 10.1534/g3.119.400725.Epub 2020-03-05.

CHANGE-seqはCRISPR-Cas9のゲノムワイドな活性に対する遺伝的およびエピジェネティックな影響を明らかにする

CHANGE-seq reveals genetic and epigenetic effects on CRISPR-Cas9 genome-wide activity.
  • Cicera R Lazzarotto
  • Nikolay L Malinin
  • Yichao Li
  • Ruochi Zhang
  • Yang Yang
  • GaHyun Lee
  • Eleanor Cowley
  • Yanghua He
  • Xin Lan
  • Kasey Jividen
  • Varun Katta
  • Natalia G Kolmakova
  • Christopher T Petersen
  • Qian Qi
  • Evgheni Strelcov
  • Samantha Maragh
  • Giedre Krenciute
  • Jian Ma
  • Yong Cheng
  • Shengdar Q Tsai
  • Nat. Biotechnol..2020 Jun;10.1038/s41587-020-0555-7. doi: 10.1038/s41587-020-0555-7.Epub 2020-06-15.

アストロサイト由来のエクソーム輸送マイクロRNA-34cは、TLR7とNF-κB/MAPK経路を介して脳虚血/再灌流障害に対して神経保護作用を示します

Astrocyte-derived exosome-transported microRNA-34c is neuroprotective against cerebral ischemia/reperfusion injury via TLR7 and the NF-κB/MAPK pathways.
  • Weicheng Wu
  • Jiaquan Liu
  • Chengbin Yang
  • Zihui Xu
  • Jianbao Huang
  • Jiyan Lin
  • Brain Res. Bull..2020 Jul;S0361-9230(20)30570-0. doi: 10.1016/j.brainresbull.2020.07.013.Epub 2020-07-16.

溶融固化印刷法（MESO-PP）を応用した新規経口リコベンダゾール製剤の設計簡素化された概念と低温を利用した3Dプリンティングのための革新的な無溶剤代替法

Design of Novel oral Ricobendazole Formulation applying Melting solidification printing process (MESO-PP): An Innovative Solvent-Free Alternative Method for 3D Printing Using a Simplified Concept and Low temperature.
  • Juan Pablo Real
  • María Eugenia Barberis
  • Nahuel M Camacho
  • Sergio Sánchez Bruni
  • Santiago D Palma
  • Int J Pharm.2020 Jul;:119653. S0378-5173(20)30637-2. doi: 10.1016/j.ijpharm.2020.119653.Epub 2020-07-16.

肥満、インスリン抵抗性、および高アンドロゲン症は、貧しい食事の質と生殖年齢の高い女性の卵巣の不整形との間のリンクを媒介する

Obesity, Insulin Resistance, and Hyperandrogenism Mediate the Link between Poor Diet Quality and Ovarian Dysmorphology in Reproductive-Aged Women.
  • Maryam Kazemi
  • Brittany Y Jarrett
  • Heidi Vanden Brink
  • Annie W Lin
  • Kathleen M Hoeger
  • Steven D Spandorfer
  • Marla E Lujan
  • Nutrients.2020 Jun;12(7). E1953. doi: 10.3390/nu12071953.Epub 2020-06-30.

超高齢者患者における胃癌に対する腹腔鏡下胃切除術の安全性と実行可能性：短期および長期の転帰

The safety and feasibility of laparoscopic gastrectomy for gastric cancer in very elderly patients: short-and long-term outcomes.
  • Ryuichi Mikami
  • Eiji Tanaka
  • Teppei Murakami
  • Satoshi Ishida
  • Yugo Matsui
  • Kenta Horita
  • Masaki Yamada
  • Takashi Nitta
  • Masahiro Mise
  • Takehisa Harada
  • Masahiko Takeo
  • Shigeki Arii
  • Surg. Today.2020 Jul;10.1007/s00595-020-02078-4. doi: 10.1007/s00595-020-02078-4.Epub 2020-07-16.

9つの細胞で生産されたノダウイルスキャプシドタンパク質のキメラウイルス様粒子に表示されたB型肝炎ウイルス"a"決定因子の免疫学的解析

Immunological Analysis of the Hepatitis B Virus "a" Determinant Displayed on Chimeric Virus-Like Particles of Nodavirus Capsid Protein Produced in 9 Cells.
  • Nathaniel Nyakaat Ninyio
  • Kok Lian Ho
  • Hui Kian Ong
  • Chean Yeah Yong
  • Hui Yee Chee
  • Muhajir Hamid
  • Wen Siang Tan
  • Vaccines (Basel).2020 Jun;8(2). E275. doi: 10.3390/vaccines8020275.Epub 2020-06-04.

チルブレイン集団発生とSARS-CoV-2との関連性の欠如：新しい免疫測定法による組織学的および血清学的所見

Lack of association between chilblains outbreak and SARS-CoV-2: histological and serological findings from a new immunoassay.
  • Vivien Hébert
  • Anne-Bénédicte Duval-Modeste
  • Pascal Joly
  • Véronique Lemée
  • Lucie Cellier
  • Fabienne Jouen
  • Benoit Veber
  • Laurent Drouot
  • Olivier Boyer
  • J. Am. Acad. Dermatol..2020 Jul;S0190-9622(20)32217-9. doi: 10.1016/j.jaad.2020.07.048.Epub 2020-07-16.

dsRNAのナノマテリアル媒介送達を介したSf9細胞におけるRNAi。ポリ-l-アルギニンポリプレックスとポリ-l-アルギニン機能化金ナノ粒子の比較

RNAi in Sf9 Cells via Nanomaterial Mediated Delivery of dsRNA: A Comparison of Poly-l-arginine Polyplexes and Poly-l-arginine-Functionalized Au Nanoparticles.
  • Jérôme Laisney
  • Dhandapani Gurusamy
  • Zeinah Elhaj Baddar
  • Subba Reddy Palli
  • Jason M Unrine
  • ACS Appl Mater Interfaces.2020 Jun;12(23):25645-25657. doi: 10.1021/acsami.0c06234.Epub 2020-05-28.

SARS-CoV-2肺炎に対するレムデシビルのエアロゾル化投与に基づく新しい薬理学的アプローチ。可能性のある合理的な治療への応用

A new pharmacological approach based on remdesivir aerosolized administration on SARS-CoV-2 pulmonary inflammation: A possible and rational therapeutic application.
  • Carlo Contini
  • Carla Enrica Gallenga
  • Giampiero Neri
  • Martina Maritati
  • Pio Conti
  • Med. Hypotheses.2020 May;144:109876. S0306-9877(20)30951-8. doi: 10.1016/j.mehy.2020.109876.Epub 2020-05-24.

揮発性有機化合物、半揮発性有機化合物、難分解性有機汚染物質、金属のための消防士のバイオモニタリング。系統的なレビュー

Biomonitoring in firefighters for volatile organic compounds, semivolatile organic compounds, persistent organic pollutants, and metals: A systematic review.
  • Michelle Engelsman
  • Leisa-Maree L Toms
  • Andrew P W Banks
  • Xianyu Wang
  • Jochen F Mueller
  • Environ. Res..2020 Apr;188:109562. S0013-9351(20)30455-2. doi: 10.1016/j.envres.2020.109562.Epub 2020-04-28.

計算モデルと分子動力学シミュレーションを用いて、ヒトcGMP特異的プロテインキナーゼIαの構造不均一性と自己抑制の構造的基盤を探る

Exploring the structural basis of conformational heterogeneity and autoinhibition of human cGMP-specific protein kinase Iα through computational modelling and molecular dynamics simulations.
  • Arooma Maryam
  • Rana Rehan Khalid
  • Sundeep Chaitanya Vedithi
  • Abdulilah Ece
  • Suleyman Selim Çınaroğlu
  • Abdul Rauf Siddiqi
  • Tom L Blundell
  • Comput Struct Biotechnol J.2020;18:1625-1638. S2001-0370(20)30305-6. doi: 10.1016/j.csbj.2020.06.016.Epub 2020-06-12.

XFELでの粘性ジェットによる生体内で成長したμNS結晶のX線回折を強化した

Enhanced X-ray diffraction of in vivo-grown μNS crystals by viscous jets at XFELs.
  • Nirupa Nagaratnam
  • Yanyang Tang
  • Sabine Botha
  • Justin Saul
  • Chufeng Li
  • Hao Hu
  • Sahba Zaare
  • Mark Hunter
  • David Lowry
  • Uwe Weierstall
  • Nadia Zatsepin
  • John C H Spence
  • Ji Qiu
  • Joshua LaBaer
  • Petra Fromme
  • Jose M Martin-Garcia
  • Acta Crystallogr F Struct Biol Commun.2020 Jun;76(Pt 6):278-289. S2053230X20006172. doi: 10.1107/S2053230X20006172.Epub 2020-05-29.

メトホルミンを担持したホスファチジルセリンナノリポソームは、ストレプトゾトシン誘発アルツハイマー病モデルにおいて、記憶障害を改善し、神経炎症を軽減する

Metformin loaded phosphatidylserine nanoliposomes improve memory deficit and reduce neuroinflammation in streptozotocin-induced Alzheimer's disease model.
  • Partow Mirzaee Saffari
  • Sakineh Alijanpour
  • Nasrin Takzaree
  • Mousa Sahebgharani
  • Shahroo Etemad-Moghadam
  • Farshid Noorbakhsh
  • Alireza Partoazar
  • Life Sci..2020 Aug;255:117861. S0024-3205(20)30611-1. doi: 10.1016/j.lfs.2020.117861.Epub 2020-05-28.

天然デンプン改質剤としてのガムコーディア（）の使用；コーンスターチの糊付け、熱、テクスチャー、およびレオロジー特性への効果

Use of Gum Cordia () as a Natural Starch Modifier; Effect on Pasting, Thermal, Textural, and Rheological Properties of Corn Starch.
  • Shahzad Hussain
  • Abdellatif A Mohamed
  • Mohamed Saleh Alamri
  • Mohamed A Ibraheem
  • Akram A Abdo Qasem
  • Syed Ali Shahzad
  • Ibrahim A Ababtain
  • Foods.2020 Jul;9(7). E909. doi: 10.3390/foods9070909.Epub 2020-07-10.

リチック多糖モノオキシゲナーゼの活性部位セグメントの構成がキシログルカンの酸化的分解を促進することを明らかにした

Configuration of active site segments in lytic polysaccharide monooxygenases steers oxidative xyloglucan degradation.
  • Peicheng Sun
  • Christophe V F P Laurent
  • Stefan Scheiblbrandner
  • Matthias Frommhagen
  • Dimitrios Kouzounis
  • Mark G Sanders
  • Willem J H van Berkel
  • Roland Ludwig
  • Mirjam A Kabel
  • Biotechnol Biofuels.2020;13:95. 1731. doi: 10.1186/s13068-020-01731-x.Epub 2020-05-29.

ラットのN-メチル-ニトロソウレア誘発前立腺癌モデルにおいて、緑茶の有酸素トレーニングとハイドロアルコール抽出物は、プロオキシダント-抗酸化バランスと病理組織学的スコアを改善した

Aerobic training and hydroalcoholic extracts of green tea improve pro-oxidant-antioxidant balance and histopathological score in the N-methyl-N-nitrosourea-induced prostate cancer model of rat.
  • Zakaria Vahabzadeh
  • Mohammadraman Molodi
  • Bahram Nikkho
  • Marziyeh Saghebjoo
  • Saber Saedmocheshi
  • Fatemeh Zamani
  • Yazdan Roshani
  • Sina Babanzadeh
  • EXCLI J.2020;19:762-772. 2019-2069. doi: 10.17179/excli2019-2069.Epub 2020-06-08.

内視鏡サーベイランスを必要としない消化器所見-ケアの負担軽減を目指して欧州消化管内視鏡学会（ESGE）のポジションステートメント

Digestive findings that do not require endoscopic surveillance - Reducing the burden of care: European Society of Gastrointestinal Endoscopy (ESGE) Position Statement.
  • Enrique Rodríguez-de-Santiago
  • Leonardo Frazzoni
  • Lorenzo Fuccio
  • Jeanin E van Hooft
  • Thierry Ponchon
  • Cesare Hassan
  • Mário Dinis-Ribeiro
  • Endoscopy.2020 Jun;52(6):491-497. doi: 10.1055/a-1137-4721.Epub 2020-04-14.

TKS5とFGD1/CDC42のシグナル伝達カスケードが交差することで、インバドポディアの形成が誘導される

Intersection of TKS5 and FGD1/CDC42 signaling cascades directs the formation of invadopodia.
  • Anna Zagryazhskaya-Masson
  • Pedro Monteiro
  • Anne-Sophie Macé
  • Alessia Castagnino
  • Robin Ferrari
  • Elvira Infante
  • Aléria Duperray-Susini
  • Florent Dingli
  • Arpad Lanyi
  • Damarys Loew
  • Elisabeth Génot
  • Philippe Chavrier
  • J. Cell Biol..2020 Sep;219(9). e201910132. doi: 10.1083/jcb.201910132.

カルシニューリンβ様相互作用プロテインキナーゼCIPK25は、シロイヌナズナにおいて低酸素下でのカリウムの恒常性を制御している

The calcineurin β-like interacting protein kinase CIPK25 regulates potassium homeostasis under low oxygen in Arabidopsis.
  • Andrea Tagliani
  • Anh Nguyet Tran
  • Giacomo Novi
  • Riccardo Di Mambro
  • Michele Pesenti
  • Gian Attilio Sacchi
  • Pierdomenico Perata
  • Chiara Pucciariello
  • J. Exp. Bot..2020 May;71(9):2678-2689. 5735510. doi: 10.1093/jxb/eraa004.

オハイオ州の若者の自殺クラスターにおけるソーシャルメディアと自殺行動の関連性

Associations Between Social Media and Suicidal Behaviors During a Youth Suicide Cluster in Ohio.
  • Elizabeth A Swedo
  • Jennifer L Beauregard
  • Sietske de Fijter
  • Luke Werhan
  • Kirkland Norris
  • Martha P Montgomery
  • Erica B Rose
  • Corinne David-Ferdon
  • Greta M Massetti
  • Susan D Hillis
  • Steven A Sumner
  • J Adolesc Health.2020 Jul;S1054-139X(20)30305-0. doi: 10.1016/j.jadohealth.2020.05.049.Epub 2020-07-07.

プロテアーゼ活性化受容体-2は、アレルギー性鼻炎におけるゾヌラ・オクリデンス-1およびクラウディン-1の発現を低下させ、上皮バリア機能障害を誘発した

Protease-Activated Receptor-2 Decreased Zonula Occlidens-1 and Claudin-1 Expression and Induced Epithelial Barrier Dysfunction in Allergic Rhinitis.
  • Jun Wang Ms
  • Xue Kang Ms
  • Zhi-Qun Huang Ms
  • Li Shen Ms
  • Qing Luo Md
  • Meng-Yue Li Ms
  • Li-Ping Luo Ms
  • Jun-Hao Tu Ms
  • Mei Han Ms
  • Jing Ye
  • Am J Rhinol Allergy.2020 Jun;:1945892420932486. doi: 10.1177/1945892420932486.Epub 2020-06-19.

Waldenström マクログロブリン血症に対する自己および同種造血細胞移植の有効性。A Systematic Review and Meta-analysis

Efficacy of Autologous and Allogeneic Hematopoietic Cell Transplantation in Waldenström Macroglobulinemia: A Systematic Review and Meta-analysis.
  • Ricardo D Parrondo
  • Tea Reljic
  • Madiha Iqbal
  • Ernesto Ayala
  • Han W Tun
  • Mohamed A Kharfan-Dabaja
  • Ambuj Kumar
  • Hemant S Murthy
  • Clin Lymphoma Myeloma Leuk.2020 Jun;S2152-2650(20)30267-6. doi: 10.1016/j.clml.2020.05.021.Epub 2020-06-02.

ペースメーカーによる金属アーチファクトの下での肺結節検出のための再構成アルゴリズムの効果

The effect of the reconstruction algorithm for the pulmonary nodule detection under the metal artifact caused by a pacemaker.
  • Noriko Kikuchi
  • Masahiro Yanagawa
  • Yukihiro Enchi
  • Akiko Nakayama
  • Yuriko Yoshida
  • Tomo Miyata
  • Akinori Hata
  • Mitsuko Tsubamoto
  • Osamu Honda
  • Noriyuki Tomiyama
  • Medicine (Baltimore).2020 Jun;99(24):e20579. 00005792-202006120-00043. doi: 10.1097/MD.0000000000020579.

デフェロキサミンは、ミトコンドリア呼吸阻害によって誘導される損傷に対する"Lull pgmシステム"加工リポアスピレーツの間葉系/幹細胞を保護する

Deferoxamine Protects Stromal/Stem Cells of "Lull pgm System"-Processed Lipoaspirates Against Damages Induced by Mitochondrial Respiration Inhibition.
  • Paolo G Morselli
  • Gioia Sorbi
  • Carlotta Feliziani
  • Claudio Muscari
  • Aesthetic Plast Surg.2020 02;44(1):168-176. 10.1007/s00266-019-01544-w. doi: 10.1007/s00266-019-01544-w.Epub 2019-11-18.

サトウキビ刈り取り業者における性感染症と関連する要因：介護への補助金

Factors associated with sexually transmitted infections in sugarcane cutters: subsidies to caring for.
  • Juliana Pontes Soares
  • Sheila Araújo Teles
  • Karlla Antonieta Amorim Caetano
  • Thaynara Ferreira Amorim
  • Maria Eliane Moreira Freire
  • Jordana de Almeida Nogueira
  • Brunna Rodrigues de Oliveira
  • Oriana Deyze Correia Paiva Leadebal
  • Patricia da Silva Araújo
  • Ana Cristina de Oliveira E Silva
  • Rev Lat Am Enfermagem.2020;28:e3306. S0104-11692020000100354. doi: 10.1590/1518-8345.3425.3306.Epub 2020-06-19.

ホジキンリンパ腫における自己造血幹細胞移植におけるBEAMおよびMITO/MELコンディショニングレジメンの比較。ホジキンリンパ腫における自己血行性幹細胞移植におけるBEAMとMITO/MELのコンディショニングレジメンの比較：効率性と治療関連毒性の分析

A Comparison of the BEAM and MITO/MEL Conditioning Regimens for Autologous Hematopoietic Stem Cell Transplantation in Hodgkin Lymphoma: An Analysis of Efficiency and Treatment-Related Toxicity.
  • Mahmut Yeral
  • Pelin Aytan
  • Burcu Gungor
  • Can Boga
  • Ali Unal
  • Yener Koc
  • Leylagul Kaynar
  • Nurhilal Buyukkurt
  • Bulent Eser
  • Hakan Ozdoğu
  • Clin Lymphoma Myeloma Leuk.2020 May;S2152-2650(20)30237-8. doi: 10.1016/j.clml.2020.05.009.Epub 2020-05-21.

イベント関連電位による脳機能分析の真髄と落とし穴：方法論的限界と臨床的信頼性に関するイタリア心理生理学・認知神経科学協会によるナラティブレビュー-パートII

Pearl and pitfalls in brain functional analysis by event-related potentials: a narrative review by the Italian Psychophysiology and Cognitive Neuroscience Society on methodological limits and clinical reliability-part II.
  • Marina de Tommaso
  • Viviana Betti
  • Tommaso Bocci
  • Nadia Bolognini
  • Francesco Di Russo
  • Francesco Fattapposta
  • Raffaele Ferri
  • Sara Invitto
  • Giacomo Koch
  • Carlo Miniussi
  • Francesco Piccione
  • Aldo Ragazzoni
  • Ferdinando Sartucci
  • Simone Rossi
  • Massimiliano Valeriani
  • Neurol. Sci..2020 Jul;10.1007/s10072-020-04527-x. doi: 10.1007/s10072-020-04527-x.Epub 2020-07-18.

筋弛緩性アトニーてんかん、軽度の大動脈弁狭窄、高近視を有する中国人患者におけるSLC6A1/NOTCH1/PRIMPOL遺伝子の同時病因変異

Concurrent pathogenic variants in SLC6A1/NOTCH1/PRIMPOL genes in a Chinese patient with myoclonic-atonic epilepsy, mild aortic valve stenosis and high myopia.
  • Haiming Yuan
  • Qingming Wang
  • Yufeng Li
  • Shuangxi Cheng
  • Jianxin Liu
  • Yanhui Liu
  • BMC Med. Genet..2020 05;21(1):93. 10.1186/s12881-020-01035-9. doi: 10.1186/s12881-020-01035-9.Epub 2020-05-06.

2型糖尿病患者におけるFraminghamリスクスコアに基づく長期的な心血管疾患リスクと血清microRNA-204レベルは関連している：観察研究からの結果

Serum microRNA-204 levels are associated with long-term cardiovascular disease risk based on the Framingham risk score in patients with type 2 diabetes: results from an observational study.
  • Rui Wang
  • Yao-Dong Ding
  • Wen Gao
  • Yu-Qiang Pei
  • Jia-Xin Yang
  • Ying-Xin Zhao
  • Xiao-Li Liu
  • Hua Shen
  • Shuo Zhang
  • Lei Yu
  • Hai-Long Ge
  • J Geriatr Cardiol.2020 Jun;17(6):330-337. jgc-17-06-330. doi: 10.11909/j.issn.1671-5411.2020.06.006.

アネキシンA5は脈絡叢のアミロイドβ誘導毒性を防ぐ：アルツハイマー病への示唆

Annexin A5 prevents amyloid-β-induced toxicity in choroid plexus: implication for Alzheimer's disease.
  • Fernando Bartolome
  • Agnieszka Krzyzanowska
  • Macarena de la Cueva
  • Consuelo Pascual
  • Desiree Antequera
  • Carlos Spuch
  • Alberto Villarejo-Galende
  • Alberto Rabano
  • Juan Fortea
  • Daniel Alcolea
  • Alberto Lleo
  • Isidro Ferrer
  • John Hardy
  • Andrey Y Abramov
  • Eva Carro
  • Sci Rep.2020 Jun;10(1):9391. 10.1038/s41598-020-66177-5. doi: 10.1038/s41598-020-66177-5.Epub 2020-06-10.

COVID-19パンデミックとそれ以降の研究の優先順位。心理科学のための行動への呼びかけ

Research priorities for the COVID-19 pandemic and beyond: A call to action for psychological science.
  • Daryl B O'Connor
  • John P Aggleton
  • Bhismadev Chakrabarti
  • Cary L Cooper
  • Cathy Creswell
  • Sandra Dunsmuir
  • Susan T Fiske
  • Susan Gathercole
  • Brendan Gough
  • Jane L Ireland
  • Marc V Jones
  • Adam Jowett
  • Carolyn Kagan
  • Maria Karanika-Murray
  • Linda K Kaye
  • Veena Kumari
  • Stephan Lewandowsky
  • Stafford Lightman
  • Debra Malpass
  • Elizabeth Meins
  • B Paul Morgan
  • Lisa J Morrison Coulthard
  • Stephen D Reicher
  • Daniel L Schacter
  • Susan M Sherman
  • Victoria Simms
  • Antony Williams
  • Til Wykes
  • Christopher J Armitage
  • Br J Psychol.2020 Jul;:e12468. doi: 10.1111/bjop.12468.Epub 2020-07-19.

血清中の脳由来神経栄養因子（BDNF）濃度は，多発性骨髄腫患者における多発性神経障害と全生存期間を予測する．

Serum brain-derived neurotrophic factor (BDNF) concentration predicts polyneuropathy and overall survival in multiple myeloma patients.
  • Aneta Szudy-Szczyrek
  • Radosław Mlak
  • Magdalena Bury-Kamińska
  • Michał Mielnik
  • Martyna Podgajna
  • Kinga Kuśmierczuk
  • Marcin Mazurek
  • Iwona Homa-Mlak
  • Michał Szczyrek
  • Janusz Krawczyk
  • Teresa Małecka-Massalska
  • Marek Hus
  • Br. J. Haematol..2020 Jun;doi: 10.1111/bjh.16862.Epub 2020-06-22.

上半規管の形態とグレノイド窩の屋根の厚さおよび顎関節の骨の変化との関連性の可能性の検討

Examination of the possible relation of the superior semicircular canal morphology with the roof thickness of the glenoid fossa and bone changes of the temporomandibular joint.
  • Gülsün Akay
  • Muhsin S Karataş
  • Özge Karadağ
  • C Özlem Üçok
  • Kahraman Güngör
  • Eur Arch Otorhinolaryngol.2020 May;10.1007/s00405-020-06063-y. doi: 10.1007/s00405-020-06063-y.Epub 2020-05-26.

正常でない動脈における自然内臓動脈解離。線維筋異形成と比較した臨床的特徴、管理、転帰

Spontaneous Visceral Artery Dissections in Otherwise Normal Arteries: Clinical Features, Management, Outcomes Compared to Fibromuscular Dysplasia.
  • Stanislav Henkin
  • Waldemar E Wysokinski
  • Marysia Tweet
  • Fadi Shamoun
  • Sailendra Naidu
  • Karolina Sutkowska
  • Kaja Bator
  • Raymond Shields
  • Eddie Green
  • Shelly Keller
  • David Hodge
  • Robert McBane
  • J. Vasc. Surg..2020 Jul;S0741-5214(20)31459-2. doi: 10.1016/j.jvs.2020.05.068.Epub 2020-07-02.

超音波異常を持つ胎児における 4p15.2p16.3、Xp22.31、および 12p11.1q11 のコピー数変異の出生前診断と分子細胞遺伝学的特徴。症例報告と文献レビュー

Prenatal Diagnosis and Molecular Cytogenetic Characterization of Copy Number Variations on 4p15.2p16.3, Xp22.31, and 12p11.1q11 in a Fetus with Ultrasound Anomalies: A Case Report and Literature Review.
  • Han Zhang
  • Qi Xi
  • Xiangyin Liu
  • Fagui Yue
  • Hongguo Zhang
  • Meiling Sun
  • Ruizhi Liu
  • Biomed Res Int.2020;2020:1761738. doi: 10.1155/2020/1761738.Epub 2020-05-27.

間欠的カンガルーマザーケアと後期早産児の母乳育児の実践：中国の異なる省の4つの病院からの結果

Intermittent kangaroo mother care and the practice of breastfeeding late preterm infants: results from four hospitals in different provinces of China.
  • Bo Zhang
  • Zhiying Duan
  • Yingxi Zhao
  • Sarah Williams
  • Stephen Wall
  • Limin Huang
  • Xiaoqin Zhang
  • Wenli Wu
  • Jieya Yue
  • Lin Zhang
  • Jun Liu
  • Gengli Zhao
  • Int Breastfeed J.2020 Jul;15(1):64. 10.1186/s13006-020-00309-5. doi: 10.1186/s13006-020-00309-5.Epub 2020-07-17.

バイアレリック ABCA4 病原性亜種を有する 506 例の家族からなるスペインのコホート研究における遺伝子型とフェノタイプの相関

Genotype-phenotype correlations in a Spanish cohort of 506 families with bi-allelic ABCA4 pathogenic variants.
  • Marta Del Pozo-Valero
  • Rosa Riveiro-Alvarez
  • Fiona Blanco-Kelly
  • Jana Aguirre-Lamban
  • Inmaculada Martin-Merida
  • Ionut-Florin Iancu
  • Saoud Swafiri
  • Isabel Lorda-Sanchez
  • Elvira Rodriguez-Pinilla
  • M Jose Trujillo-Tiebas
  • Belen Jimenez-Rolando
  • Ester Carreño
  • Ignacio Mahillo-Fernandez
  • Carlo Rivolta
  • Marta Corton
  • Almudena Avila-Fernandez
  • Blanca García Sandoval
  • Carmen Ayuso
  • Am. J. Ophthalmol..2020 Jun;S0002-9394(20)30323-8. doi: 10.1016/j.ajo.2020.06.027.Epub 2020-06-30.

創傷治癒のための自己治癒力と抗菌性を有する二重架橋ヒアルロン酸/ε-ポリリジンヒドロゲルを用いたムール貝由来の二重架橋ヒアルロン酸/ε-ポリリジンヒドロゲル

Mussel-Inspired Dual-Cross-linking Hyaluronic Acid/ε-Polylysine Hydrogel with Self-Healing and Antibacterial Properties for Wound Healing.
  • Shuai Liu
  • Xin Liu
  • Yanhan Ren
  • Penghui Wang
  • Yajie Pu
  • Rong Yang
  • Xiaoxue Wang
  • Xiaoyan Tan
  • Zhiwen Ye
  • Victor Maurizot
  • Bo Chi
  • ACS Appl Mater Interfaces.2020 Jun;12(25):27876-27888. doi: 10.1021/acsami.0c00782.Epub 2020-06-12.

ヒトケラチノサイト細胞株に対する光触媒活性を低下させ、生体適合性を向上させたCeOナノドット被覆TiOナノ粒子を開発した

Development of CeO nanodot encrusted TiO nanoparticles with reduced photocatalytic activity and increased biocompatibility towards a human keratinocyte cell line.
  • Alexander Morlando
  • Marcela Chaki Borrás
  • Yaser Rehman
  • Shahnaz Bakand
  • Philip Barker
  • Ronald Sluyter
  • Konstantin Konstantinov
  • J Mater Chem B.2020 May;8(18):4016-4028. doi: 10.1039/d0tb00629g.

米国およびフランスにおける母乳、乳児用粉ミルク、または幼児用栄養飲料によるマンガンの1日摂取量の推定。充足度および毒性閾値との比較

Estimating daily intakes of manganese due to breast milk, infant formulas, or young child nutritional beverages in the United States and France: Comparison to sufficiency and toxicity thresholds.
  • Erika J Mitchell
  • Seth H Frisbie
  • Stéphane Roudeau
  • Asuncion Carmona
  • Richard Ortega
  • J Trace Elem Med Biol.2020 Jul;62:126607. S0946-672X(20)30172-3. doi: 10.1016/j.jtemb.2020.126607.Epub 2020-07-09.

水中および淡水魚サンプル中の水銀種の前濃縮および定量のための冷蒸気原子吸光光度法を用いた固相抽出における吸着剤としての固定化活性炭の利用

Immobilized Activated Carbon as Sorbent in Solid Phase Extraction with Cold Vapor Atomic Absorption Spectrometry for the Preconcentration and Determination of Mercury Species in Water and Freshwater Fish Samples.
  • Arnon Thongsaw
  • Ratana Sananmuang
  • Yuthapong Udnan
  • Richmond J Ampiah-Bonney
  • Wipharat Chuachuad Chaiyasith
  • Anal Sci.2019 Nov;35(11):1195-1202. doi: 10.2116/analsci.19P164.Epub 2019-07-12.

GemC1は、p73との直接的な相互作用と転写制御を介して、多毛新生を制御しています

GemC1 governs multiciliogenesis through direct interaction with and transcriptional regulation of p73.
  • Maria-Eleni Lalioti
  • Marina Arbi
  • Ioannis Loukas
  • Konstantina Kaplani
  • Argyro Kalogeropoulou
  • Georgia Lokka
  • Christina Kyrousi
  • Athanasia Mizi
  • Theodore Georgomanolis
  • Natasa Josipovic
  • Dimitrios Gkikas
  • Vladimir Benes
  • Panagiotis K Politis
  • Argyris Papantonis
  • Zoi Lygerou
  • Stavros Taraviras
  • J. Cell. Sci..2019 06;132(11). jcs228684. doi: 10.1242/jcs.228684.Epub 2019-06-03.

下部尿路症状や尿閉を有する男性に対する前立腺のチュリウムレーザー経尿道的気化切除術と経尿道的前立腺切除術（UNBLOCS）：無作為化比較試験

Thulium laser transurethral vaporesection of the prostate versus transurethral resection of the prostate for men with lower urinary tract symptoms or urinary retention (UNBLOCS): a randomised controlled trial.
  • Hashim Hashim
  • Jo Worthington
  • Paul Abrams
  • Grace Young
  • Hilary Taylor
  • Sian M Noble
  • Sara T Brookes
  • Nikki Cotterill
  • Tobias Page
  • K Satchi Swami
  • J Athene Lane
  • Lancet.2020 Jul;396(10243):50-61. S0140-6736(20)30537-7. doi: 10.1016/S0140-6736(20)30537-7.

サトウキビに関連する窒素固定性根粒菌の多様性：サッカラム（Saccharum spp

Diversity of nitrogen-fixing rhizobacteria associated with sugarcane: a comprehensive study of plant-microbe interactions for growth enhancement in Saccharum spp.
  • Rajesh Kumar Singh
  • Pratiksha Singh
  • Hai-Bi Li
  • Qi-Qi Song
  • Dao-Jun Guo
  • Manoj K Solanki
  • Krishan K Verma
  • Mukesh K Malviya
  • Xiu-Peng Song
  • Prakash Lakshmanan
  • Li-Tao Yang
  • Yang-Rui Li
  • BMC Plant Biol..2020 May;20(1):220. 10.1186/s12870-020-02400-9. doi: 10.1186/s12870-020-02400-9.Epub 2020-05-18.

低コストのポータブル 3 D 仮想現実ジェスチャー媒介シミュレータのトレーニングと低侵襲手術の基本的な心理運動スキルを学習するための使用。開発と内容の妥当性の研究

Use of a Low-Cost Portable 3D Virtual Reality Gesture-Mediated Simulator for Training and Learning Basic Psychomotor Skills in Minimally Invasive Surgery: Development and Content Validity Study.
  • Fernando Alvarez-Lopez
  • Marcelo Fabián Maina
  • Francesc Saigí-Rubió
  • J. Med. Internet Res..2020 Jul;22(7):e17491. v22i7e17491. doi: 10.2196/17491.Epub 2020-07-14.

トリスソミー21は、インターフェロン受容体の投与量の増加を介してキヌレニン経路を活性化する

Trisomy 21 activates the kynurenine pathway via increased dosage of interferon receptors.
  • Rani K Powers
  • Rachel Culp-Hill
  • Michael P Ludwig
  • Keith P Smith
  • Katherine A Waugh
  • Ross Minter
  • Kathryn D Tuttle
  • Hannah C Lewis
  • Angela L Rachubinski
  • Ross E Granrath
  • María Carmona-Iragui
  • Rebecca B Wilkerson
  • Darcy E Kahn
  • Molishree Joshi
  • Alberto Lleó
  • Rafael Blesa
  • Juan Fortea
  • Angelo D'Alessandro
  • James C Costello
  • Kelly D Sullivan
  • Joaquin M Espinosa
  • Nat Commun.2019 10;10(1):4766. 10.1038/s41467-019-12739-9. doi: 10.1038/s41467-019-12739-9.Epub 2019-10-18.

糖尿病の有無にかかわらず入院した患者におけるCOVID-19の特徴と転帰

Characteristics and outcomes of COVID-19 in hospitalized patients with and without diabetes.
  • Abdallah Al-Salameh
  • Jean-Philippe Lanoix
  • Youssef Bennis
  • Claire Andrejak
  • Etienne Brochot
  • Guillaume Deschasse
  • Hervé Dupont
  • Vincent Goeb
  • Maité Jaureguy
  • Sylvie Lion
  • Julien Maizel
  • Julien Moyet
  • Benoit Vaysse
  • Rachel Desailloud
  • Olivier Ganry
  • Jean-Luc Schmit
  • Jean-Daniel Lalau
  • Diabetes Metab. Res. Rev..2020 Jul;:e3388. doi: 10.1002/dmrr.3388.Epub 2020-07-19.

切除可能な膵頭癌および膵周囲癌に対する内視鏡的胆道ドレナージの全国的な実践と転帰

Nationwide practice and outcomes of endoscopic biliary drainage in resectable pancreatic head and periampullary cancer.
  • Anouk E J Latenstein
  • Tara M Mackay
  • Nadine C M van Huijgevoort
  • Bert A Bonsing
  • Koop Bosscha
  • Lieke Hol
  • Marco J Bruno
  • Marielle M E van Coolsen
  • Sebastiaan Festen
  • Erwin van Geenen
  • Bas Groot Koerkamp
  • Gerrit J M Hemmink
  • Ignace H J T de Hingh
  • Geert Kazemier
  • Hans Lubbinge
  • Vincent E de Meijer
  • I Quintus Molenaar
  • Rutger Quispel
  • Hjalmar C van Santvoort
  • Tom C J Seerden
  • Martijn W J Stommel
  • Niels G Venneman
  • Robert C Verdonk
  • Marc G Besselink
  • Jeanin E van Hooft
  • HPB (Oxford).2020 Jul;S1365-182X(20)31056-X. doi: 10.1016/j.hpb.2020.06.009.Epub 2020-07-16.

慢性リンパ性白血病患者のキメラ抗原受容体T細胞産生を改善するイブルチニブ

Ibrutinib for improved chimeric antigen receptor T cell production for chronic lymphocytic leukemia patients.
  • Fuli Fan
  • Hyeon Joo Yoo
  • Sophia Stock
  • Lei Wang
  • Yibin Liu
  • Maria-Luisa Schubert
  • Sanmei Wang
  • Brigitte Neuber
  • Angela Hückelhoven-Krauss
  • Ulrike Gern
  • Anita Schmitt
  • Carsten Müller-Tidow
  • Peter Dreger
  • Michael Schmitt
  • Leopold Sellner
  • Int. J. Cancer.2020 Jul;doi: 10.1002/ijc.33212.Epub 2020-07-19.

同種造血細胞移植後の慢性移植片対宿主病予防のためのイクサゾミブ

Ixazomib for chronic Graft-Versus-Host Disease prophylaxis following allogeneic hematopoietic cell transplantation.
  • Saurabh Chhabra
  • Alexis Visotcky
  • Marcelo C Pasquini
  • Fenlu Zhu
  • Xiaoying Tang
  • Mei-Jie Zhang
  • Robert Thompson
  • Sameem Abedin
  • Anita D'Souza
  • Binod Dhakal
  • William R Drobyski
  • Timothy S Fenske
  • James H Jerkins
  • J Douglas Rizzo
  • Lyndsey Runaas
  • Wael Saber
  • Nirav N Shah
  • Bronwen E Shaw
  • Mary M Horowitz
  • Parameswaran N Hari
  • Mehdi Hamadani
  • Biol. Blood Marrow Transplant..2020 Jul;S1083-8791(20)30414-6. doi: 10.1016/j.bbmt.2020.07.005.Epub 2020-07-09.

認知機能障害は股関節骨折手術後の再手術リスクに影響を与える：Norwegian Hip Fracture Registerに報告された87,573件の手術の結果

Cognitive impairment influences the risk of reoperation after hip fracture surgery: results of 87,573 operations reported to the Norwegian Hip Fracture Register.
  • Målfrid Holen Kristoffersen
  • Eva Dybvik
  • Ole Martin Steihaug
  • Torbjørn Berge Kristensen
  • Lars Birger Engesaeter
  • Anette Hylen Ranhoff
  • Jan-Erik Gjertsen
  • Acta Orthop.2020 04;91(2):146-151. doi: 10.1080/17453674.2019.1709712.Epub 2020-01-13.

タバコの煙にさらされたマウスの磁気共鳴分光法による骨格筋の生体エネルギー欠損の早期検出

Early detection of skeletal muscle bioenergetic deficit by magnetic resonance spectroscopy in cigarette smoke-exposed mice.
  • Sandra Pérez-Rial
  • Esther Barreiro
  • María Jesús Fernández-Aceñero
  • María Encarnación Fernández-Valle
  • Nicolás González-Mangado
  • Germán Peces-Barba
  • PLoS ONE.2020;15(6):e0234606. PONE-D-19-15081. doi: 10.1371/journal.pone.0234606.Epub 2020-06-22.

添加物は、高水分スイートコーンカーネルサイレージにおける代謝プロファイル、微生物群集、および抗生物質耐性遺伝子の分布に影響を与える

Additives affect the distribution of metabolic profile, microbial communities and antibiotic resistance genes in high-moisture sweet corn kernel silage.
  • Zhe Wu
  • Yingning Luo
  • Jinze Bao
  • Ying Luo
  • Zhu Yu
  • Bioresour. Technol..2020 Jul;315:123821. S0960-8524(20)31093-2. doi: 10.1016/j.biortech.2020.123821.Epub 2020-07-11.

乳児アカゲザル脳のα-トコフェロール立体異性体プロファイルは、乳児用ミルク中のα-トコフェロールの供給源によって異なる影響を受ける

Infant Rhesus Macaque Brain α-Tocopherol Stereoisomer Profile Is Differentially Impacted by the Source of α-Tocopherol in Infant Formula.
  • Matthew J Kuchan
  • Katherine M Ranard
  • Priyankar Dey
  • Sookyoung Jeon
  • Geoff Y Sasaki
  • Karen J Schimpf
  • Richard S Bruno
  • Martha Neuringer
  • John W Erdman
  • J. Nutr..2020 Jul;nxaa174. doi: 10.1093/jn/nxaa174.Epub 2020-07-02.

副腎ステロイド産生の非古典的障害と21-ヒドロキシラーゼ欠乏症とバックドアアンドロゲン経路を合併した臨床的ジレンマ.ミニレビューと症例報告．

Non-Classic Disorder of Adrenal Steroidogenesis and Clinical Dilemmas in 21-Hydroxylase Deficiency Combined with Backdoor Androgen Pathway. Mini-Review and Case Report.
  • Marta Sumińska
  • Klaudia Bogusz-Górna
  • Dominika Wegner
  • Marta Fichna
  • Int J Mol Sci.2020 Jun;21(13). E4622. doi: 10.3390/ijms21134622.Epub 2020-06-29.

2型糖尿病および心血管疾患患者における肥満と心血管アウトカムとの関連。TECOSからの洞察

Association of obesity with cardiovascular outcomes in patients with type 2 diabetes and cardiovascular disease: Insights from TECOS.
  • Neha J Pagidipati
  • Yinggan Zheng
  • Jennifer B Green
  • Darren K McGuire
  • Robert J Mentz
  • Svati Shah
  • Pablo Aschner
  • Tuncay Delibasi
  • Helena W Rodbard
  • Cynthia M Westerhout
  • Rury R Holman
  • Eric D Peterson
  • Am. Heart J..2020 01;219:47-57. S0002-8703(19)30274-1. doi: 10.1016/j.ahj.2019.09.016.Epub 2019-10-20.

膠芽腫における循環血管新生細胞：CAC誘導性の新生血管化と反応性の新生血管化の決定的な機能的差異の解明に向けて

Circulating angiogenic cells in glioblastoma: toward defining crucial functional differences in CAC-induced neoplastic versus reactive neovascularization.
  • Karin Huizer
  • Andrea Sacchetti
  • Sigrid Swagemakers
  • Peter J van der Spek
  • Wim Dik
  • Dana A Mustafa
  • Johan M Kros
  • Neurooncol Adv.2020 Jan-Dec;2(1):vdaa040. vdaa040. doi: 10.1093/noajnl/vdaa040.Epub 2020-04-01.

MYH2ミオパチー，新しい症例が劣性型の臨床と病理学的スペクトルを拡大している．

MYH2 myopathy, a new case expands the clinical and pathological spectrum of the recessive form.
  • Roberta Telese
  • Serena Pagliarani
  • Alberto Lerario
  • Patrizia Ciscato
  • Gigliola Fagiolari
  • Denise Cassandrini
  • Nadia Grimoldi
  • Giorgio Conte
  • Claudia Cinnante
  • Filippo M Santorelli
  • Giacomo P Comi
  • Monica Sciacco
  • Lorenzo Peverelli
  • Mol Genet Genomic Med.2020 Jun;:e1320. doi: 10.1002/mgg3.1320.Epub 2020-06-24.

スチレンと無水マレイン酸の反復的なRAFT媒介共重合：配列および長さ制御された共重合体とその可溶化脂質膜への応用に向けて

Iterative RAFT-mediated copolymerization of styrene and maleic anhydride: towards sequence- and length-controlled copolymers and their applications for solubilizing lipid membranes.
  • Randy D Cunningham
  • Adrian H Kopf
  • Barend O W Elenbaas
  • Bastiaan B P Staal
  • Rueben Pfukwa
  • J Antoinette Killian
  • Bert Klumperman
  • Biomacromolecules.2020 Jul;doi: 10.1021/acs.biomac.0c00736.Epub 2020-07-16.

IgG4関連疾患と診断された眼窩ロサイードルフマン病：症例報告

Orbital Rosai-Dorfman disease initially diagnosed as IgG4-related disease: a case report.
  • Nishanth S Iyengar
  • Danielle Golub
  • Michelle W McQuinn
  • Travis Hill
  • Karen Tang
  • Sharon L Gardner
  • David H Harter
  • Chandranath Sen
  • David A Staffenberg
  • Kristen Thomas
  • Zachary Elkin
  • Irina Belinsky
  • Christopher William
  • Acta Neuropathol Commun.2020 Jul;8(1):113. 10.1186/s40478-020-00995-6. doi: 10.1186/s40478-020-00995-6.Epub 2020-07-18.

没入型技術を活用して、コミュニティ設定でのオピオイド過剰摂取逆転訓練へのアクセスを拡大する。無作為化対照同等性試験の結果

Leveraging immersive technology to expand access to opioid overdose reversal training in community settings: Results from a randomized controlled equivalence trial.
  • Natalie Herbert
  • Sydney Axson
  • Leeann Siegel
  • Kyle Cassidy
  • Ann Marie Hoyt-Brennan
  • Clare Whitney
  • Allison Herens
  • Nicholas A Giordano
  • Drug Alcohol Depend.2020 Jul;214:108160. S0376-8716(20)30325-2. doi: 10.1016/j.drugalcdep.2020.108160.Epub 2020-07-02.

双極性障害におけるファーマコゲノミクスの潜在的標的：現在の検査の検討と治療選択を個別化するための意思決定支援ツールの開発

Potential pharmacogenomic targets in bipolar disorder: considerations for current testing and the development of decision support tools to individualize treatment selection.
  • Alfredo B Cuéllar-Barboza
  • Susan L McElroy
  • Marin Veldic
  • Balwinder Singh
  • Simon Kung
  • Francisco Romo-Nava
  • Nicolas A Nunez
  • Alejandra Cabello-Arreola
  • Brandon J Coombes
  • Miguel Prieto
  • Hannah K Betcher
  • Katherine M Moore
  • Stacey J Winham
  • Joanna M Biernacka
  • Mark A Frye
  • Int J Bipolar Disord.2020 Jul;8(1):23. 10.1186/s40345-020-00184-3. doi: 10.1186/s40345-020-00184-3.Epub 2020-07-04.

デュアル可溶性エポキシドヒドロラーゼ阻害剤/PPAR-γアゴニストは腎線維化を抑制する

Dual soluble epoxide hydrolase inhibitor/PPAR-γ agonist attenuates renal fibrosis.
  • Anna Stavniichuk
  • Md Abdul Hye Khan
  • Michael M Yeboah
  • Marla A Chesnik
  • Wojciech K Jankiewicz
  • Markus Hartmann
  • René Blöcher
  • Theresa Kircher
  • Olexiy Savchuk
  • Ewgenij Proschak
  • John D Imig
  • Prostaglandins Other Lipid Mediat..2020 Jun;150:106472. S1098-8823(20)30065-4. doi: 10.1016/j.prostaglandins.2020.106472.Epub 2020-06-20.

SPARCは肝動脈化学塞栓術後の予後と負の相関があり、ERK/MMPシグナル伝達経路を介して肝細胞癌の増殖と転移を促進する

SPARC Negatively Correlates With Prognosis After Transarterial Chemoembolization and Facilitates Proliferation and Metastasis of Hepatocellular Carcinoma via ERK/MMP Signaling Pathways.
  • Yao Liu
  • Ying Feng
  • Xiaojing Wang
  • Xue Yang
  • Ying Hu
  • Yuxin Li
  • Qun Zhang
  • Yunyi Huang
  • Ke Shi
  • Chongping Ran
  • Jie Hou
  • Li Jiang
  • Junfa Li
  • Xianbo Wang
  • Front Oncol.2020;10:813. doi: 10.3389/fonc.2020.00813.Epub 2020-05-21.

山火事後の北極圏ツンドラへの北方高木の転入に対する菌根菌の接種の全体的な影響は限定的であり、種特異的な反応を示した

Limited overall impacts of ectomycorrhizal inoculation on recruitment of boreal trees into Arctic tundra following wildfire belie species-specific responses.
  • Rebecca E Hewitt
  • F Stuart Chapin
  • Teresa N Hollingsworth
  • Michelle C Mack
  • Adrian V Rocha
  • D Lee Taylor
  • PLoS ONE.2020;15(7):e0235932. PONE-D-20-09652. doi: 10.1371/journal.pone.0235932.Epub 2020-07-09.

医学雑誌に投稿された仕事の開示書：医学雑誌編集者国際委員会からの提案

A disclosure form for work submitted to medical journals: a proposal from the International Committee of Medical Journal Editors.
  • Darren B Taichman
  • Joyce Backus
  • Christopher Baethge
  • Howard Bauchner
  • Annette Flanagin
  • Fernando Florenzano
  • Frank A Frizelle
  • Fiona Godlee
  • Laragh Gollogly
  • Abraham Haileamlak
  • Sung-Tae Hong
  • Richard Horton
  • Astrid James
  • Christine Laine
  • Pamela W Miller
  • Anja Pinborg
  • Eric J Rubin
  • Peush Sahni
  • N. Z. Med. J..2020 02;133(1509):6-8. Epub 2020-02-07.

機能化されたPHB顆粒は、組換えバチルス・メガテリウムのコレステロールとアナログの効率的な側鎖切断のための基礎を提供します

Functionalized PHB granules provide the basis for the efficient side-chain cleavage of cholesterol and analogs in recombinant Bacillus megaterium.
  • Adrian Gerber
  • Michael Kleser
  • Rebekka Biedendieck
  • Rita Bernhardt
  • Frank Hannemann
  • Microb. Cell Fact..2015 Jul;14:107. 10.1186/s12934-015-0300-y. doi: 10.1186/s12934-015-0300-y.Epub 2015-07-29.

インスリノーマ局在化のための低用量選択的動脈カルシウム刺激試験：単施設での連続5症例の経験

Low-dose Selective Arterial Calcium Stimulation Test for Localizing Insulinoma: A Single-center Experience of Five Consecutive Cases.
  • Tomonobu Hatoko
  • Takaaki Murakami
  • Masakatsu Sone
  • Daisuke Yabe
  • Toshihiko Masui
  • Yuji Nakamoto
  • Akihiro Furuta
  • Norimitsu Uza
  • Yuzo Kodama
  • Norio Harada
  • Masahito Ogura
  • Akihiro Yasoda
  • Nobuya Inagaki
  • Intern. Med..2020 Jun;doi: 10.2169/internalmedicine.4396-20.Epub 2020-06-30.

転移性去勢抵抗性前立腺癌の転移時の原発病変再生検におけるAKR1C3発現は、第一選択療法としてのアビラテロンの有効性の低さと強く関連している

AKR1C3 expression in primary lesion rebiopsy at the time of metastatic castration-resistant prostate cancer is strongly associated with poor efficacy of abiraterone as a first-line therapy.
  • Jinge Zhao
  • Mengni Zhang
  • Jiandong Liu
  • Zhenhua Liu
  • Pengfei Shen
  • Ling Nie
  • Wenhao Guo
  • Diming Cai
  • Jiyan Liu
  • Cameron M Armstrong
  • Guangxi Sun
  • Junru Chen
  • Sha Zhu
  • Jindong Dai
  • Haoran Zhang
  • Peng Zhao
  • Xingming Zhang
  • Xiaoxue Yin
  • Xudong Zhu
  • Yuchao Ni
  • Ni Chen
  • Hao Zeng
  • Prostate.2019 09;79(13):1553-1562. doi: 10.1002/pros.23875.Epub 2019-07-11.

また、牛骨ミネラルとコラーゲン膜で覆われた自家製下顎骨ブロックを使用して移植された隆起部にインプラントを埋入した場合の10年間の平均追跡調査をレトロスペクティブに行った

A retrospective 10-year mean follow-up of implants placed in ridges grafted using autogenous mandibular blocks covered with bovine bone mineral and collagen membrane.
  • Matteo Chiapasco
  • Grazia Tommasato
  • David Palombo
  • Massimo Del Fabbro
  • Clin Oral Implants Res.2020 Apr;31(4):328-340. doi: 10.1111/clr.13571.Epub 2020-01-20.

ジンセノサイド化合物-MC1は、AMP活性化プロテインキナーゼ依存性機構を介して心筋細胞の酸化ストレスとアポトーシスを減少させる

Ginsenoside compound-Mc1 attenuates oxidative stress and apoptosis in cardiomyocytes through an AMP-activated protein kinase-dependent mechanism.
  • So-Hyeon Hong
  • Hwan-Jin Hwang
  • Joo Won Kim
  • Jung A Kim
  • You Bin Lee
  • Eun Roh
  • Kyung Mook Choi
  • Sei Hyun Baik
  • Hye Jin Yoo
  • J Ginseng Res.2020 Jul;44(4):664-671. S1226-8453(18)30420-2. doi: 10.1016/j.jgr.2019.08.006.Epub 2019-08-26.

腸球のブラシ境界の組み立てを促進するために、接着複合体の足場であるANKS4Bを先端微小絨毛に標的としている

A cryptic sequence targets the adhesion complex scaffold ANKS4B to apical microvilli to promote enterocyte brush border assembly.
  • Maura J Graves
  • Samaneh Matoo
  • Myoung Soo Choi
  • Zachary A Storad
  • Rawnag A El Sheikh Idris
  • Brooke K Pickles
  • Prashun Acharya
  • Paula E Shinder
  • Taylen O Arvay
  • Scott William Crawley
  • J. Biol. Chem..2020 Jul;jbc.RA120.013790. doi: 10.1074/jbc.RA120.013790.Epub 2020-07-06.

心房細動と上室性不整脈の治療のためのカテーテルアブレーションは透視検査の使用なしに。急性の有効性と安全性

Catheter Ablation for Treatment of Atrial Fibrillation and Supraventricular Arrhythmias Without Fluoroscopy Use: Acute Efficacy and Safety.
  • Eduardo B Saad
  • Charles Slater
  • Luiz Antonio Oliveira Inácio
  • Gustavo Vignoli Dos Santos
  • Lucas Carvalho Dias
  • Luiz Eduardo Montenegro Camanho
  • Arq. Bras. Cardiol..2020 Jun;114(6):1015-1026. S0066-782X2020000701015. doi: 10.36660/abc.20200096.Epub 2020-07-03.

RLBP1網膜色素変性症（RLBP1 RP）の患者体験をよりよく理解し、患者が報告したアウトカム（PRO）を評価するための質的面接

Qualitative Interviews to Better Understand the Patient Experience and Evaluate Patient-Reported Outcomes (PRO) in RLBP1 Retinitis Pigmentosa (RLBP1 RP).
  • Jane Green
  • Chloe Tolley
  • Sarah Bentley
  • Rob Arbuckle
  • Marie Burstedt
  • James Whelan
  • Karen Holopigian
  • Kali Stasi
  • Brigitte Sloesen
  • Claudio Spera
  • Jean-Yves Deslandes
  • Anmol Mullins
  • Adv Ther.2020 Jun;37(6):2884-2901. 10.1007/s12325-020-01275-4. doi: 10.1007/s12325-020-01275-4.Epub 2020-05-05.

潰瘍性大腸炎とクローン病の組織標本におけるアルド-ケト還元酵素ファミリー1メンバーC3の違いをマイクロプロテオミクスと免疫組織化学で明らかにした

Microproteomics and Immunohistochemistry Reveal Differences in Aldo-Keto Reductase Family 1 Member C3 in Tissue Specimens of Ulcerative Colitis and Crohn's Disease.
  • Karim Arafah
  • Mark Kriegsmann
  • Marcus Renner
  • Felix Lasitschka
  • Margaux Fresnais
  • Katharina Kriegsmann
  • Moritz von Winterfeld
  • Benjamin Goeppert
  • Jörg Kriegsmann
  • Rita Casadonte
  • Daniel Kazdal
  • Philippe Bulet
  • Rémi Longuespée
  • Proteomics Clin Appl.2020 Jul;14(4):e1900110. doi: 10.1002/prca.201900110.Epub 2020-02-16.

プロテインホスファターゼ2A阻害剤CIP2A, SET, PME-1の3つのタンパク質が媒介するリン酸化プロテオームと薬剤応答効果

Phosphoproteome and drug-response effects mediated by the three protein phosphatase 2A inhibitor proteins CIP2A, SET, and PME-1.
  • Otto Kauko
  • Susumu Y Imanishi
  • Evgeny Kulesskiy
  • Laxman Yetukuri
  • Teemu Daniel Laajala
  • Mukund Sharma
  • Karolina Pavic
  • Anna Aakula
  • Christian Rupp
  • Mikael Jumppanen
  • Pekka Haapaniemi
  • Luyao Ruan
  • Bhagwan Yadav
  • Veronika Suni
  • Taru Varila
  • Garry L Corthals
  • Jüri Reimand
  • Krister Wennerberg
  • Tero Aittokallio
  • Jukka Westermarck
  • J. Biol. Chem..2020 Mar;295(13):4194-4211. RA119.011265. doi: 10.1074/jbc.RA119.011265.Epub 2020-02-18.

内皮がチェロノイディス・カルボナリア大動脈の電場刺激誘発収縮を調節する

Endothelium modulates electrical field stimulation-induced contractions of Chelonoidis carbonaria aortic rings.
  • Rafael Campos
  • Felipe Fernandes Jacintho
  • José Britto-Júnior
  • Fabíola Z Mónica
  • Alberto Fernando Oliveira Justo
  • André Sampaio Pupo
  • Ronilson Agnaldo Moreno
  • Valéria Barbosa de Souza
  • André Almeida Schenka
  • Edson Antunes
  • Gilberto De Nucci
  • Comp. Biochem. Physiol. C Toxicol. Pharmacol..2020 Jul;233:108763. S1532-0456(20)30063-6. doi: 10.1016/j.cbpc.2020.108763.Epub 2020-04-11.

免疫療法を試験するためのヒト化マウスNPC-PDXモデルの確立と特性評価

Establishment and Characterization of Humanized Mouse NPC-PDX Model for Testing Immunotherapy.
  • Wai Nam Liu
  • Shin Yie Fong
  • Wilson Wei Sheng Tan
  • Sue Yee Tan
  • Min Liu
  • Jia Ying Cheng
  • Sherlly Lim
  • Lisda Suteja
  • Edwin Kunxiang Huang
  • Jerry Kok Yen Chan
  • Narayanan Gopalakrishna Iyer
  • Joe Poh Sheng Yeong
  • Darren Wan-Teck Lim
  • Qingfeng Chen
  • Cancers (Basel).2020 Apr;12(4). E1025. doi: 10.3390/cancers12041025.Epub 2020-04-22.

乳酸脱水素酵素阻害はIL-21と相乗的に作用し、CD8 T細胞の幹細胞化と抗腫瘍免疫を促進する

Lactate dehydrogenase inhibition synergizes with IL-21 to promote CD8 T cell stemness and antitumor immunity.
  • Dalton Hermans
  • Sanjivan Gautam
  • Juan C García-Cañaveras
  • Daniel Gromer
  • Suman Mitra
  • Rosanne Spolski
  • Peng Li
  • Stephen Christensen
  • Rosa Nguyen
  • Jian-Xin Lin
  • Jangsuk Oh
  • Ning Du
  • Sharon Veenbergen
  • Jessica Fioravanti
  • Risa Ebina-Shibuya
  • Christopher Bleck
  • Leonard M Neckers
  • Joshua D Rabinowitz
  • Luca Gattinoni
  • Warren J Leonard
  • Proc. Natl. Acad. Sci. U.S.A..2020 03;117(11):6047-6055. 1920413117. doi: 10.1073/pnas.1920413117.Epub 2020-03-02.

アビラテロンとプレドニゾンによる治療を受けた転移性ホルモン感受性前立腺がん患者における前立腺表面抗原の変化パターンの特定

Identifying Prostate Surface Antigen Patterns of Change in Patients with Metastatic Hormone Sensitive Prostate Cancer Treated with Abiraterone and Prednisone.
  • Iris Y Sheng
  • Jaleh Fallah
  • Ruby Gupta
  • Hong Li
  • Kimberly Allman
  • Allison Martin
  • Pedro Barata
  • Moshe C Ornstein
  • Timothy D Gilligan
  • Brian I Rini
  • Jorge A Garcia
  • Target Oncol.2020 Jul;10.1007/s11523-020-00734-w. doi: 10.1007/s11523-020-00734-w.Epub 2020-07-13.

ナタネ茎のSclerotinia sclerotiorumに対する抵抗性の向上とナタネ藁由来の溶存有機物の菌糸体上での阻害に対する土壌中のセレンの強化と改善

Enhancement and improvement of selenium in soil to the resistance of rape stem against Sclerotinia sclerotiorum and the inhibition of dissolved organic matter derived from rape straw on mycelium.
  • Qin Cheng
  • Wei Jia
  • Chengxiao Hu
  • Guangyu Shi
  • Dandan Yang
  • Miaomiao Cai
  • Ting Zhan
  • Yanni Tang
  • Yingjie Zhou
  • Xuecheng Sun
  • Xiaohu Zhao
  • Environ. Pollut..2020 May;265(Pt A):114827. S0269-7491(20)30775-2. doi: 10.1016/j.envpol.2020.114827.Epub 2020-05-19.

ホルモン受容体陽性転移性乳癌患者におけるパルボシクリブの早期投与量の強度低下が臨床転帰に及ぼす影響

Impact of early dose intensity reduction of Palbociclib on clinical outcomes in patients with hormone-receptor-positive metastatic breast cancer.
  • Bahar Moftakhar
  • Manidhar Lekkala
  • Myla Strawderman
  • Tae C Smith
  • Philip Meacham
  • Bryan Fitzgerald
  • Carla I Falkson
  • Ajay Dhakal
  • Breast Cancer Res. Treat..2020 Jul;10.1007/s10549-020-05793-1. doi: 10.1007/s10549-020-05793-1.Epub 2020-07-15.

感覚野を供給する動脈上に増殖した未破裂のGemella Morbillorum感染性動脈瘤に対するY字型動脈グラフトを用いた頭蓋内バイパス術．症例報告

Intracranial-Intracranial Bypass Using a "Y"-Shaped Artery Graft for Growing Unruptured Gemella Morbillorum Infectious Aneurysm on Artery Supplying Sensory Cortex: A Case Report.
  • Masato Shiba
  • Naoki Toma
  • Munenari Ikezawa
  • Yusuke Kuroda
  • Yume Suzuki
  • Reona Asada
  • Yoichi Miura
  • Ryuta Yasuda
  • Hidenori Suzuki
  • World Neurosurg.2020 Jul;S1878-8750(20)31577-1. doi: 10.1016/j.wneu.2020.07.056.Epub 2020-07-16.

COVID-19パンデミックアウトブレイク中の離乳センターの責任 - ベルリン・ブランデンブルクPOST-SAVEモデルで示されたCOVID-19患者のICU容量の割り当てのための推奨事項

[Responsibilities of Weaning Centers during the COVID-19 Pandemic Outbreak - Recommendations for the Assignment of ICU Capacities in COVID-19 Patients as shown by the Berlin-Brandenburg POST-SAVE-Model].
  • B Wiesner
  • M Bachmann
  • T-G Blum
  • S Forchheim
  • J Geiseler
  • A Kassin
  • E Kretzschmar
  • S Weber-Carstens
  • M Westhoff
  • M Witzenrath
  • C Grohé
  • Pneumologie.2020 Jun;74(6):358-365. doi: 10.1055/a-1153-9710.Epub 2020-04-15.

バイオインフォマティクスに基づくlncRNA-miRNA-mRNAとTF制御ネットワークの解析により、食道扁平上皮癌の機能遺伝子を明らかにした

Bioinformatics-based Analysis of the lncRNA-miRNA-mRNA and TF regulatory networks reveal functional genes in esophageal squamous cell carcinoma.
  • Zhimin Ye
  • Jun Fang
  • Zhun Wang
  • Lei Wang
  • Bin Li
  • TongXin Liu
  • Yuezhen Wang
  • JianFeng Hua
  • FangZheng Wang
  • ZhenFu Fu
  • Biosci. Rep..2020 Jul;BSR20201727. doi: 10.1042/BSR20201727.Epub 2020-07-14.

アルファルファ蛋白質単離物のアミノ酸プロファイル、形態、電気泳動パターン、生理活性電位および機能特性に及ぼす処理およびpHの影響

Influence of processing and pH on amino acid profile, morphology, electrophoretic pattern, bioactive potential and functional characteristics of alfalfa protein isolates.
  • Prashant Sahni
  • Savita Sharma
  • Vijay Kumar Reddy Surasani
  • Food Chem.2020 Jul;333:127503. S0308-8146(20)31365-0. doi: 10.1016/j.foodchem.2020.127503.Epub 2020-07-10.

原発性移植片不全による同所性心臓移植後の全人工心臓患者における上大静脈狭窄症の静脈形成術の成功例

Successful venoplasty of superior vena cava stenosis in a patient with a total artificial heart after orthotopic heart transplantation due to primary graft failure.
  • Anita Phancao
  • Aly El Banayosy
  • Stephen P Lee
  • David W Vanhooser
  • Michael D Harper
  • Douglas A Horstmanshof
  • James W Long
  • Michael M Koerner
  • J Card Surg.2020 Jul;doi: 10.1111/jocs.14877.Epub 2020-07-19.

固形腫瘍患者に対するデュルバルマブとトレメリムマブの併用療法とデュルバルマブまたはトレメリムマブ単剤療法との比較。システマティックレビューおよびメタアナリシス

Durvalumab and tremelimumab combination therapy versus durvalumab or tremelimumab monotherapy for patients with solid tumors: A systematic review and meta-analysis.
  • Bi-Cheng Wang
  • Peng-Cheng Li
  • Ji-Quan Fan
  • Guo-He Lin
  • Quentin Liu
  • Medicine (Baltimore).2020 Jul;99(28):e21273. 00005792-202007100-00133. doi: 10.1097/MD.0000000000021273.

新しいアプローチ法を用いてナノ材料の皮膚感作性を調査するための有害事象パスウェイ（AOP）の枠組 みを適用した

Application of the adverse outcome pathway (AOP) framework for investigating skin sensitization potential of nanomaterials using new approach methods.
  • Soraia Ferreira Bezerra
  • Bruna Dos Santos Rodrigues
  • Artur Christian Garcia da Silva
  • Renato Ivan de Ávila
  • Hallison Ranieri Gonçalves Brito
  • Emílio Ramos Cintra
  • Danillo Fabrini Maciel Costa Veloso
  • Eliana Martins Lima
  • Marize Campos Valadares
  • Contact Derm..2020 Jul;doi: 10.1111/cod.13669.Epub 2020-07-19.

股関節全置換術後の遅発性無菌性合併症と敗血症性合併症の鑑別のためのマルチディテクターCTの価値

Value of multidetector computed tomography for the differentiation of delayed aseptic and septic complications after total hip arthroplasty.
  • Jaime Isern-Kebschull
  • Xavier Tomas
  • Ana Isabel García-Díez
  • Laura Morata
  • Ignacio Moya
  • José Ríos
  • Alex Soriano
  • Skeletal Radiol..2020 Jun;49(6):893-902. 10.1007/s00256-019-03355-1. doi: 10.1007/s00256-019-03355-1.Epub 2020-01-03.

地中海式ダイエットのアドヒアランスに対する社会経済的および環境的決定要因の影響：ギリシャ、アテネ都市圏における自治体レベルの空間分析

The impact of socioeconomic and environmental determinants on Mediterranean diet adherence: a municipal-level spatial analysis in Athens metropolitan area, Greece.
  • Thomas Tsiampalis
  • Antigoni Faka
  • Matina Kouvari
  • Theodora Psaltopoulou
  • Christos Pitsavos
  • Christos Chalkias
  • Demosthenes B Panagiotakos
  • Int J Food Sci Nutr.2020 Jul;:1-12. doi: 10.1080/09637486.2020.1791057.Epub 2020-07-12.

ニコチンアミドは、ラットのフルクトース誘発性メタボリックシンドロームにおいて、コリン作動系を介して炎症や酸化ストレスを軽減します

Nicotinamide reduces inflammation and oxidative stress via the cholinergic system in fructose-induced metabolic syndrome in rats.
  • J D Villeda-González
  • J L Gómez-Olivares
  • L A Baiza-Gutman
  • L Manuel-Apolinar
  • L Damasio-Santana
  • C Millán-Pacheco
  • S Ángeles-Mejía
  • M C Cortés-Ginez
  • M Cruz-López
  • C J Vidal-Moreno
  • M Díaz-Flores
  • Life Sci..2020 Jun;250:117585. S0024-3205(20)30333-7. doi: 10.1016/j.lfs.2020.117585.Epub 2020-03-31.

HPV 陽性口腔咽頭扁平上皮癌を有する女性におけるヒトパピローマウイルス関連性生殖器病理

Human Papillomavirus-Associated Anogenital Pathology in Females With HPV-Positive Oropharyngeal Squamous Cell Carcinoma.
  • Alyssa Larish
  • Linda Yin
  • Gretchen Glaser
  • Eric Moore
  • Jamie Bakkum-Gamez
  • David Routman
  • Daniel Ma
  • Daniel Price
  • Jeffrey Janus
  • Katharine Price
  • Ashish Chintakuntlawar
  • Michelle Neben-Wittich
  • Robert Foote
  • Kathryn Van Abel
  • Otolaryngol Head Neck Surg.2020 Jul;:194599820941499. doi: 10.1177/0194599820941499.Epub 2020-07-14.

膵臓癌治療のための細胞毒性リガンドをアンカーとするナチュラルキラー細胞の再誘導を合理的に設計した

Rationally designed redirection of natural killer cells anchoring a cytotoxic ligand for pancreatic cancer treatment.
  • Young Eun Lee
  • Anna Ju
  • Hwi Wan Choi
  • Jin-Chul Kim
  • Eunice EunKyeong Kim
  • Tae Sung Kim
  • Hyo Jeong Kang
  • Sang-Yeob Kim
  • Jin-Young Jang
  • Ja-Lok Ku
  • Song Cheol Kim
  • Eunsung Jun
  • Mihue Jang
  • J Control Release.2020 Jul;S0168-3659(20)30398-9. doi: 10.1016/j.jconrel.2020.07.016.Epub 2020-07-16.

非神経性表面外胚葉ロゼット形成とF-アクチン動態が哺乳類神経管閉鎖を駆動することを明らかにした

Non-neural surface ectodermal rosette formation and F-actin dynamics drive mammalian neural tube closure.
  • Chengji J Zhou
  • Yu Ji
  • Kurt Reynolds
  • Moira McMahon
  • Michael A Garland
  • Shuwen Zhang
  • Bo Sun
  • Ran Gu
  • Mohammad Islam
  • Yue Liu
  • Tianyu Zhao
  • Grace Hsu
  • Janet Iwasa
  • Biochem. Biophys. Res. Commun..2020 Jun;526(3):647-653. S0006-291X(20)30635-5. doi: 10.1016/j.bbrc.2020.03.138.Epub 2020-04-02.

ナイーブなヒトESCにおける自家分泌FGFシグナルによる不均一性を克服することで、ランダムX染色体不活性化のモデル化が可能となる

Overcoming Autocrine FGF Signaling-Induced Heterogeneity in Naive Human ESCs Enables Modeling of Random X Chromosome Inactivation.
  • Chenrui An
  • Guihai Feng
  • Jixiang Zhang
  • Shiwei Cao
  • Ying Wang
  • Nannan Wang
  • Falong Lu
  • Qi Zhou
  • Haoyi Wang
  • Cell Stem Cell.2020 Jul;S1934-5909(20)30269-1. doi: 10.1016/j.stem.2020.06.002.Epub 2020-07-08.

従属栄養性硝化-好気性脱窒が可能な新規リン酸蓄積生物Arthrobacter sp.HHEP5によるリン・窒素除去安全性評価、除去特性評価、機構解明、排水処理

Phosphorus and nitrogen removal by a novel phosphate-accumulating organism, Arthrobacter sp. HHEP5 capable of heterotrophic nitrification-aerobic denitrification: Safety assessment, removal characterization, mechanism exploration and wastewater treatment.
  • Mengyu Zhang
  • Luqing Pan
  • Liping Liu
  • Chen Su
  • Le Dou
  • Zhaopeng Su
  • Ziyan He
  • Bioresour. Technol..2020 Sep;312:123633. S0960-8524(20)30905-6. doi: 10.1016/j.biortech.2020.123633.Epub 2020-06-04.

腫瘍内遺伝的異質性を有する膠芽腫の機能的に異なる相互作用を有するがん細胞サブ集団の同定

Identification of functionally distinct and interacting cancer cell subpopulations from glioblastoma with intratumoral genetic heterogeneity.
  • Min Guo
  • Marjolein van Vliet
  • Jian Zhao
  • Teresita Díaz de Ståhl
  • Mikael S Lindström
  • Huaitao Cheng
  • Susanne Heller
  • Monica Nistér
  • Daniel Hägerstrand
  • Neurooncol Adv.2020 Jan-Dec;2(1):vdaa061. vdaa061. doi: 10.1093/noajnl/vdaa061.Epub 2020-05-27.

血漿性ホルモン濃度の縦断的変化は、10年間の日系男性におけるCT測定による局所的な脂肪率の変化と相関している

Longitudinal changes in plasma sex hormone concentrations correlate with changes in CT-measured regional adiposity among Japanese American men over 10 years.
  • Kathryn T Dinh
  • John K Amory
  • Alvin M Matsumoto
  • Brett T Marck
  • Wilfred Y Fujimoto
  • Donna L Leonetti
  • Edward J Boyko
  • Stephanie T Page
  • Katya B Rubinow
  • Clin. Endocrinol. (Oxf).2020 Jul;doi: 10.1111/cen.14278.Epub 2020-07-07.

Epichloë festucae由来の核タンパク質NsiAは、MAPキナーゼMpkBと相互作用し、共生感染や菌糸体融合に必要な遺伝子の発現を制御していることが明らかになった

A nuclear protein NsiA from Epichloë festucae interacts with a MAP kinase MpkB and regulates the expression of genes required for symbiotic infection and hyphal cell fusion.
  • Aiko Tanaka
  • Shota Kamiya
  • Yoshino Ozaki
  • Shinichi Kameoka
  • Yuka Kayano
  • Saikia Sanjay
  • Fumitake Akano
  • Aiko Uemura
  • Hiroki Takagi
  • Ryohei Terauchi
  • Jun-Ichi Maruyama
  • Hamzeh Haj Hammadeh
  • André Fleissner
  • Barry Scott
  • Daigo Takemoto
  • Mol. Microbiol..2020 Jul;doi: 10.1111/mmi.14568.Epub 2020-07-07.

ブラジルにおける大豆ルーパーChrysodeixis includens（Lepidoptera: Noctuidae）によるキチン合成阻害剤殺虫剤に対する圃場発生抵抗性

Field-evolved resistance to chitin synthesis inhibitor insecticides by soybean looper, Chrysodeixis includens (Lepidoptera: Noctuidae), in Brazil.
  • Regis F Stacke
  • Daniela N Godoy
  • Venicius E Pretto
  • Fábio M Führ
  • Patricia da S Gubiani
  • Bruna L Hettwer
  • Cínthia G Garlet
  • Junior C Somavilla
  • Dionei S Muraro
  • Oderlei Bernardi
  • Chemosphere.2020 Jun;259:127499. S0045-6535(20)31693-3. doi: 10.1016/j.chemosphere.2020.127499.Epub 2020-06-29.

線維筋異形成と線維筋異形成の遺伝学的研究、メタアナリシスと患者の臨床的特徴への影響。ARCADIA-POL試験

Genetic Study of and Fibromuscular Dysplasia, Meta-Analysis and Effects on Clinical Features of Patients: The ARCADIA-POL Study.
  • Ewa Warchol-Celinska
  • Takiy Berrandou
  • Aleksander Prejbisz
  • Adrien Georges
  • Delia Dupré
  • Magdalena Januszewicz
  • Elzbieta Florczak
  • Katarzyna Jozwik-Plebanek
  • Piotr Dobrowolski
  • Witold Smigielski
  • Wojciech Drygas
  • Jacek Kadziela
  • Adam Witkowski
  • Marek Kabat
  • Malgorzata Szczerbo-Trojanowska
  • Marco Pappaccogli
  • Alexandre Persu
  • Xavier Jeunemaitre
  • Andrzej Januszewicz
  • Nabila Bouatia-Naji
  • Hypertension.2020 Jul;76(1):e4-e7. doi: 10.1161/HYPERTENSIONAHA.120.14793.Epub 2020-06-01.

ANKRD26遺伝子の5'UTRの変異と骨髄性悪性腫瘍の素因を持つ遺伝性血小板減少症との関係。エジプトでの研究

Relation between mutations in the 5' UTR of ANKRD26 gene and inherited thrombocytopenia with predisposition to myeloid malignancies. An Egyptian study.
  • Nahla Ibrahim Zidan
  • Doaa Metwally AbdElmonem
  • Haitham Mohamed Elsheikh
  • Elsayed Anany Metwally
  • Wesam AbdElmonem Mokhtar
  • Gamal Mohamed Osman
  • Platelets.2020 Jul;:1-9. doi: 10.1080/09537104.2020.1790512.Epub 2020-07-13.

11beta-ヒドロキシステロイド脱水素酵素1型および2型は、コルチゾール分泌性副腎腺腫においてアップレギュレーションおよびダウンレギュレーションされている

11beta-Hydroxysteroid dehydrogenase types 1 and 2 are up- and downregulated in cortisol-secreting adrenal adenomas.
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  • Francesco Aragona
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急性アキレス腱損傷の治療と腱周囲癒着の予防を目的とした新しいコラーゲンベースの医療機器（ElastiCo®）の評価。インビトロでの生体適合性およびインビボでの調査

Evaluation of a new collagen-based medical device (ElastiCo®) for the treatment of acute Achilles tendon injury and prevention of peritendinous adhesions: An in vitro biocompatibility and in vivo investigation.
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  • Gianluca Giavaresi
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  • Veronica Casagranda
  • Daniele Pressato
  • Milena Fini
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抗生物質耐性メタロ-β-ラクタマーゼに対する阻害効果が期待されるトリアゾール系阻害剤の構造研究

Structural studies of triazole inhibitors with promising inhibitor effects against antibiotic resistance metallo-β-lactamases.
  • Zeeshan Muhammad
  • Susann Skagseth
  • Marc Boomgaren
  • Sundus Akhter
  • Christopher Fröhlich
  • Aya Ismael
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慢性腎臓病のステージを越えて心筋異常を定義します。心臓磁気共鳴画像研究

Defining Myocardial Abnormalities Across the Stages of Chronic Kidney Disease: A Cardiac Magnetic Resonance Imaging Study.
  • Manvir K Hayer
  • Ashwin Radhakrishnan
  • Anna M Price
  • Boyang Liu
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  • Luca Biasiolli
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  • Jonathan N Townend
  • Richard P Steeds
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肺疾患のトランスレーショナル研究における細胞を用いた治療法の動物モデルへの洞察自然発生性喘息の馬は正しい選択か？

Insights into animal models for cell-based therapies in translational studies of lung diseases: Is the horse with naturally occurring asthma the right choice?
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  • Luca Stucchi
  • Enrica Zucca
  • Jean Pierre Lavoie
  • Fausto Cremonesi
  • Francesco Ferrucci
  • Cytotherapy.2019 05;21(5):525-534. S1465-3249(19)30033-7. doi: 10.1016/j.jcyt.2019.02.010.Epub 2019-03-29.

マウスの実験的炎症性腸疾患におけるペニーロワイヤルフェノール抽出物による炎症と大腸障害の軽減

Reduction of inflammation and colon injury by a Pennyroyal phenolic extract in experimental inflammatory bowel disease in mice.
  • João Rocha
  • Rosa Direito
  • Ana Lima
  • Joana Mota
  • Margarida Gonçalves
  • Maria Paula Duarte
  • João Solas
  • Bruno Felício Peniche
  • Adelaide Fernandes
  • Rui Pinto
  • Ricardo Boavida Ferreira
  • Bruno Sepodes
  • Maria-Eduardo Figueira
  • Biomed. Pharmacother..2019 Oct;118:109351. S0753-3322(19)32012-8. doi: 10.1016/j.biopha.2019.109351.Epub 2019-08-22.

腫瘍細胞表面付着性ペプチド-薬物複合体プロドラッグナノ粒子は、腫瘍の転移を抑制し、治療効果を増大させます

Tumor-Cell-Surface Adherable Peptide-Drug Conjugate Prodrug Nanoparticles Inhibit Tumor Metastasis and Augment Treatment Efficacy.
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  • Jingjing Wang
  • Ying Qian
  • Rongfeng Hu
  • Jiayu Zou
  • Chenqi Zhu
  • Yuan Zhu
  • Shuyang Qi
  • Xiaobin Jia
  • Li Wu
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  • Nano Lett..2020 Jun;20(6):4153-4161. doi: 10.1021/acs.nanolett.0c00152.Epub 2020-05-28.

下水汚泥の嫌気性消化物を肥料として使用したアルカリ性貧弱砂質土壌および泥炭基質上での施肥。トマトの生育および土壌性状に及ぼす影響

Anaerobic digestates from sewage sludge used as fertilizer on a poor alkaline sandy soil and on a peat substrate: Effects on tomato plants growth and on soil properties.
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  • Enrico Camelin
  • Tonia Tommasi
  • Debora Fino
  • Massimo Pugliese
  • J. Environ. Manage..2020 Sep;269:110767. S0301-4797(20)30699-X. doi: 10.1016/j.jenvman.2020.110767.Epub 2020-05-28.

セリン異化は呼吸が損なわれたときにNADHを供給します

Serine Catabolism Feeds NADH when Respiration Is Impaired.
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  • Juan Carlos Garcia Canaveras
  • Zihong Chen
  • Lin Wang
  • Lingfan Liang
  • Cholsoon Jang
  • Johannes A Mayr
  • Zhaoyue Zhang
  • Jonathan M Ghergurovich
  • Le Zhan
  • Shilpy Joshi
  • Zhixian Hu
  • Melanie R McReynolds
  • Xiaoyang Su
  • Eileen White
  • Raphael J Morscher
  • Joshua D Rabinowitz
  • Cell Metab..2020 Apr;31(4):809-821.e6. S1550-4131(20)30114-5. doi: 10.1016/j.cmet.2020.02.017.Epub 2020-03-17.

アポリポ蛋白AIとEは多発性硬化症における灰白質に対する神経軸索損傷と関連している

Apolipoproteins AI and E are associated with neuroaxonal injury to gray matter in multiple sclerosis.
  • Mason McComb
  • Robert Parambi
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  • Mary Lou Bodziak
  • Dejan Jakimovski
  • Niels Bergsland
  • Aleksandra Maceski
  • Bianca Weinstock-Guttman
  • Jens Kuhle
  • Robert Zivadinov
  • Murali Ramanathan
  • Mult Scler Relat Disord.2020 Jul;45:102389. S2211-0348(20)30464-8. doi: 10.1016/j.msard.2020.102389.Epub 2020-07-11.

イタリア産発酵乳ギョードゥの微生物学的特性評価

Microbiological characterization of Gioddu, an Italian fermented milk.
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  • Giuseppe Blaiotta
  • Ilario Ferrocino
  • Nicoletta P Mangia
  • Andrea Osimani
  • Vesna Milanović
  • Federica Cardinali
  • Cristiana Cesaro
  • Cristiana Garofalo
  • Francesca Clementi
  • Marina Pasquini
  • Maria Federica Trombetta
  • Luca Cocolin
  • Lucia Aquilanti
  • Int. J. Food Microbiol..2020 Jun;323:108610. S0168-1605(20)30104-5. doi: 10.1016/j.ijfoodmicro.2020.108610.Epub 2020-03-20.

ニワトリ胚の生体内ラベリングによる第一心野と第二心野の組み込みと直腸心管の将来的な運命

Incorporation of the first and second heart fields and prospective fate of the straight heart tube via in vivo labeling of chicken embryos.
  • Villavicencio Guzmán Laura
  • Salazar García Marcela
  • Jaime Cruz Ricardo
  • Lazzarini Roberto
  • Toledano-Toledano Filiberto
  • Concepción Sánchez Gómez
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ブラジル・リオデジャネイロ州に生息するグレイトトリガーフィッシュBalistes capriscus Gmelin, 1789とクイーントリガーフィッシュB. vetula Linnaeus, 1758 (Osteichthyes: Balistidae)のメタゾアン寄生の群集生態

Community ecology of the metazoan parasites of the grey triggerfish, Balistes capriscus Gmelin, 1789 and queen triggerfish B. vetula Linnaeus,1758 (Osteichthyes: Balistidae) from the State of Rio de Janeiro, Brazil.
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  • Aline R Paraguassú
  • José L Luque
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カスパーゼ-8はアポトーシス、ネクロプトーシス、パイロプトーシスの分子スイッチである

Caspase-8 is the molecular switch for apoptosis, necroptosis and pyroptosis.
  • Melanie Fritsch
  • Saskia D Günther
  • Robin Schwarzer
  • Marie-Christine Albert
  • Fabian Schorn
  • J Paul Werthenbach
  • Lars M Schiffmann
  • Neil Stair
  • Hannah Stocks
  • Jens M Seeger
  • Mohamed Lamkanfi
  • Martin Krönke
  • Manolis Pasparakis
  • Hamid Kashkar
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低酸素腫瘍の陽子線治療における生物学的に重み付けされた線量計算のためのOERモデルと結合したFLUKAモンテカルロコードを開発した

The FLUKA Monte Carlo code coupled with an OER model for biologically weighted dose calculations in proton therapy of hypoxic tumors.
  • Tordis Johnsen Dahle
  • Espen Rusten
  • Camilla Hanquist Stokkevåg
  • Antti Silvoniemi
  • Andrea Mairani
  • Lars Fredrik Fjæra
  • Eivind Rørvik
  • Helge Henjum
  • Pauliina Wright
  • Camilla Grindeland Boer
  • Sarita Forsback
  • Heikki Minn
  • Eirik Malinen
  • Kristian Smeland Ytre-Hauge
  • Phys Med.2020 Jul;76:166-172. S1120-1797(20)30163-0. doi: 10.1016/j.ejmp.2020.07.003.Epub 2020-07-16.

高血糖マウスおよび全球脳虚血・再灌流傷害マウスの海馬における柑橘類カワチバンカンの果皮およびオーラプテンの神経保護効果

[Neuroprotective effects of the peel of Citrus kawachiensis (Kawachi Bankan) and auraptene in the hippocampus of hyperglycemia mice and global cerebral ischemia/reperfusion injury mice].
  • Satoshi Okuyama
  • Atsushi Sawamoto
  • Mitsunari Nakajima
  • Yoshiko Furukawa
  • Nippon Yakurigaku Zasshi.2020;155(4):214-219. doi: 10.1254/fpj.20022.

神経保護作用と血管新生作用の相乗効果を有する桂皮酸誘導体の設計・合成・生物学的評価

Design, synthesis and biological evaluation of cinnamic acid derivatives with synergetic neuroprotection and angiogenesis effect.
  • Wen-Xi Zhang
  • Hui Wang
  • He-Rong Cui
  • Wen-Bo Guo
  • Fei Zhou
  • De-Sheng Cai
  • Bing Xu
  • Xiao-Hui Jia
  • Xue-Mei Huang
  • Yu-Qin Yang
  • Hong-Shan Chen
  • Jin-Chai Qi
  • Peng-Long Wang
  • Hai-Min Lei
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Bacillus toyonensis COPE52は脂質・脂肪酸組成を修飾し、抗真菌活性を発揮し、塩分条件下でのトマト植物の生育を促進する

Bacillus toyonensis COPE52 Modifies Lipid and Fatty Acid Composition, Exhibits Antifungal Activity, and Stimulates Growth of Tomato Plants Under Saline Conditions.
  • Daniel Rojas-Solis
  • Miguel A Vences-Guzmán
  • Christian Sohlenkamp
  • Gustavo Santoyo
  • Curr. Microbiol..2020 Jun;10.1007/s00284-020-02069-1. doi: 10.1007/s00284-020-02069-1.Epub 2020-06-05.

糖尿病治療における絶食（FIT）試験：2型糖尿病患者における絶食を模倣した食事の断続的な使用の効果に関する無作為化、対照、評価者盲検介入試験のための研究プロトコル

Fasting in diabetes treatment (FIT) trial: study protocol for a randomised, controlled, assessor-blinded intervention trial on the effects of intermittent use of a fasting-mimicking diet in patients with type 2 diabetes.
  • Elske L van den Burg
  • Marjolein P Schoonakker
  • Petra G van Peet
  • M Elske van den Akker-van Marle
  • Ko Willems van Dijk
  • Valter D Longo
  • Hildo J Lamb
  • Mattijs E Numans
  • Hanno Pijl
  • BMC Endocr Disord.2020 Jun;20(1):94. 10.1186/s12902-020-00576-7. doi: 10.1186/s12902-020-00576-7.Epub 2020-06-24.

ヒト歯髄におけるパルバルブミン、サブスタンスP、カルシトニン遺伝子関連ペプチド免疫陽性軸索は、静脈瘤の分布が異なる

Parvalbumin-, substance P- and calcitonin gene-related peptide-immunopositive axons in the human dental pulp differ in their distribution of varicosities.
  • Sook Kyung Park
  • Seung Ki Choi
  • Youn Gyung Kim
  • So Young Choi
  • Jin Wook Kim
  • Sang Hyeok Seo
  • Ji Hyun Lee
  • Yong Chul Bae
  • Sci Rep.2020 Jun;10(1):10672. 10.1038/s41598-020-67804-x. doi: 10.1038/s41598-020-67804-x.Epub 2020-06-30.