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日本語AIでPubMedを検索

歯科医師情報サイトTOP / PubMed論文検索

日本語AIでPubMedを検索

PubMedの提供する医学論文データベースを日本語で検索できます。AI(Deep Learning)を活用した機械翻訳エンジンにより、精度高く日本語へ翻訳された論文をご参照いただけます。
対象期間    ～ 

2020年07月 みんなが読んでいる論文

スイスにおける職業別の身体的・精神的病的罹患の有病率と自殺死亡率との相関：スイス国民コホート（1990年～2014年）の結果

Prevalence of somatic and psychiatric morbidity across occupations in Switzerland and its correlation with suicide mortality: results from the Swiss National Cohort (1990-2014).
  • M Schmid
  • L Michaud
  • N Bovio
  • I Guseva Canu
  • BMC Psychiatry.2020 Jun;20(1):324. 10.1186/s12888-020-02733-7. doi: 10.1186/s12888-020-02733-7.Epub 2020-06-22.

O-グリコシルトランスフェラーゼのレクチンドメインの差動スプライシングは、ペプチドと糖ペプチドの両方の嗜好性を調節する

Differential splicing of the lectin domain of an O-glycosyltransferase modulates both peptide and glycopeptide preferences.
  • Carolyn May
  • Suena Ji
  • Zulfeqhar A Syed
  • Leslie Revoredo
  • Earnest James Paul Daniel
  • Thomas A Gerken
  • Lawrence A Tabak
  • Nadine L Samara
  • Kelly G Ten Hagen
  • J. Biol. Chem..2020 Jul;jbc.RA120.014700. doi: 10.1074/jbc.RA120.014700.Epub 2020-07-15.

Chascomús 連鎖浅い湖水系（アルゼンチン）の排水流出口と受水域におけるステロイドホルモンとエストロゲン活性

Steroid hormones and estrogenic activity in the wastewater outfall and receiving waters of the Chascomús chained shallow lakes system (Argentina).
  • Anelisa González
  • Kevin J Kroll
  • Cecilia Silva-Sanchez
  • Pedro Carriquiriborde
  • Juan I Fernandino
  • Nancy D Denslow
  • Gustavo M Somoza
  • Sci. Total Environ..2020 Jul;743:140401. S0048-9697(20)33923-1. doi: 10.1016/j.scitotenv.2020.140401.Epub 2020-07-06.

大動脈弁と僧帽弁を持つ患者の心室頻拍アブレーションのための経皮的心室間セプタールアクセスは、肋骨下心エコーと透視下でガイドされている

Percutaneous Interventricular Septal Access Guided by Subcostal Echocardiography and Fluoroscopy for Ventricular Tachycardia Ablation in a Patient with Aortic and Mitral Mechanical Valves.
  • Dursun Aras
  • Serkan Topaloglu
  • Ozcan Ozeke
  • Firat Ozcan
  • Serkan Cay
  • Zehra Golbasi
  • J Innov Card Rhythm Manag.2019 Jul;10(7):3719-3721. icrm.2019.100702. doi: 10.19102/icrm.2019.100702.Epub 2019-07-15.

甲状腺ホルモンβ受容体の変異を持つ患者は、パフォーマンスモニタリングのためのADHDに似た表現型を示す：電気生理学的研究

Patients with mutations of the Thyroid hormone beta-receptor show an ADHD-like phenotype for performance monitoring: an electrophysiological study.
  • Jan Uter
  • Marcus Heldmann
  • Berenike Rogge
  • Martina Obst
  • Julia Steinhardt
  • Georg Brabant
  • Carla Moran
  • Krishna Chatterjee
  • Thomas F Münte
  • Neuroimage Clin.2020 Mar;26:102250. S2213-1582(20)30087-5. doi: 10.1016/j.nicl.2020.102250.Epub 2020-03-19.

小児の末梢血および胃粘膜における感染症と形質細胞および骨髄性樹状細胞との関係

Relationship between Infection and Plasmacytoid and Myeloid Dendritic Cells in Peripheral Blood and Gastric Mucosa of Children.
  • Anna Helmin-Basa
  • Małgorzata Wiese-Szadkowska
  • Anna Szaflarska-Popławska
  • Maciej Kłosowski
  • Milena Januszewska
  • Magdalena Bodnar
  • Andrzej Marszałek
  • Lidia Gackowska
  • Jacek Michalkiewicz
  • Mediators Inflamm..2019;2019:7190596. doi: 10.1155/2019/7190596.Epub 2019-11-11.

17α-ヒドロキシラーゼ欠損症による先天性副腎過形成症の小児の臨床的、生化学的、遺伝的特徴

Clinical, biochemical and genetic characteristics of children with congenital adrenal hyperplasia due to 17α-hydroxylase deficiency.
  • Adlyne Reena Asirvatham
  • Karthik Balachandran
  • Packiamary Jerome
  • Vettriselvi Venkatesan
  • Teena Koshy
  • Shriraam Mahadevan
  • J. Pediatr. Endocrinol. Metab..2020 Jul;/j/jpem.ahead-of-print/jpem-2020-0050/jpem-2020-0050.xml. doi: 10.1515/jpem-2020-0050.Epub 2020-07-13.

高出力パルス増幅用ゲルマニウム添加クラッド付き超低NAステップインデックス大モード領域Ybドープファイバ

Ultra-low NA step-index large mode area Yb-doped fiber with a germanium doped cladding for high power pulse amplification.
  • Raghuraman Sidharthan
  • Di Lin
  • Kang Jie Lim
  • Huizi Li
  • Serene Huiting Lim
  • Chen Jian Chang
  • Yue Men Seng
  • Song Liang Chua
  • Yongmin Jung
  • David J Richardson
  • Seongwoo Yoo
  • Opt Lett.2020 Jul;45(14):3828-3831. 433190. doi: 10.1364/OL.396157.

インドの海洋保護区でのレクリエーション・ダイビング活動によるサンゴの被害。説明責任を果たさないことが「コモンズの悲劇」につながっている

Coral damage by recreational diving activities in a Marine Protected Area of India: Unaccountability leading to 'tragedy of the not so commons'.
  • Kalyan De
  • Mandar Nanajkar
  • Sambhaji Mote
  • Baban Ingole
  • Mar. Pollut. Bull..2020 Jun;155:111190. S0025-326X(20)30308-8. doi: 10.1016/j.marpolbul.2020.111190.Epub 2020-05-04.

機能評価は日常の視覚機能を予測するか？軽・中等度加齢黄斑変性症における視覚機能検査とQOL

Does functional assessment predict everyday visual functioning? Visual function testing and quality of life in mild/moderate age-related macular degeneration.
  • Geoffrey K Broadhead
  • Thomas Hong
  • John R Grigg
  • Peter McCluskey
  • Timothy E Schlub
  • Kimberly Spooner
  • Andrew A Chang
  • Int Ophthalmol.2020 Jul;10.1007/s10792-020-01508-z. doi: 10.1007/s10792-020-01508-z.Epub 2020-07-14.

乳酸菌を代替抗生物質増殖促進剤として与えることにより、ニホンウズラ（）の卵外・内卵の品質が改善された

Improves in external and internal egg quality of Japanese quail () by giving lactic acid bacteria as alternative antibiotic growth promoter.
  • Widya Paramita Lokapirnasari
  • Anam Al Arif
  • Soeharsono Soeharsono
  • Anisah Fathinah
  • Rifqi Najwan
  • Hana Cipka Pramuda Wardhani
  • Nabil Fariz Noorrahman
  • Khoirul Huda
  • Nuria Ulfah
  • Andreas Berny Yulianto
  • Iran J Microbiol.2019 Oct;11(5):406-411.

フィンランドで全国的に組織されたヘリコプター救急医療サービスの最初の7年間 - 質の高い登録簿からのデータ

The first seven years of nationally organized helicopter emergency medical services in Finland - the data from quality registry.
  • Anssi Saviluoto
  • Johannes Björkman
  • Anna Olkinuora
  • Ilkka Virkkunen
  • Hetti Kirves
  • Piritta Setälä
  • Ilkka Pulkkinen
  • Päivi Laukkanen-Nevala
  • Lasse Raatiniemi
  • Helena Jäntti
  • Timo Iirola
  • Jouni Nurmi
  • Scand J Trauma Resusc Emerg Med.2020 May;28(1):46. 10.1186/s13049-020-00739-4. doi: 10.1186/s13049-020-00739-4.Epub 2020-05-29.

標的媒介薬物動態モデルのMichaelis-Menten近似を用いた健康なボランティアまたは高コレステロール血症患者におけるアリロクマブの母集団薬物動態解析-生物学的製剤ライセンス申請支援-.第1部

Population Pharmacokinetic Analysis of Alirocumab in Healthy Volunteers or Hypercholesterolemic Subjects Using a Michaelis-Menten Approximation of a Target-Mediated Drug Disposition Model-Support for a Biologics License Application Submission: Part I.
  • Jean-Marie Martinez
  • Aurélie Brunet
  • Fabrice Hurbin
  • A Thomas DiCioccio
  • Clémence Rauch
  • David Fabre
  • Clin Pharmacokinet.2019 01;58(1):101-113. 10.1007/s40262-018-0669-y. doi: 10.1007/s40262-018-0669-y.

光化学系II阻害剤としてのインドール窒素ハイブリッドの合理的設計・合成・評価

Rational Design, Synthesis and Evaluation of Indole Nitrogen Hybrids as Photosystem II Inhibitors.
  • Jéssica Maria de Souza
  • Bruno Rodrigues Fazolo
  • Jhully Wellen Ferreira Lacerda
  • Mariana de Souza Moura
  • Arielly Celestino Rodrigues Dos Santos
  • Leonardo Gomes de Vasconcelos
  • Paulo Teixeira de Sousa Junior
  • Evandro Luiz Dall'Oglio
  • Akbar Ali
  • Olívia Moreira Sampaio
  • Lucas Campos Curcino Vieira
  • Photochem. Photobiol..2020 Jun;doi: 10.1111/php.13295.Epub 2020-06-13.

2種のグリプチンとその主な合成不純物のin vitro毒性評価

In vitro toxic evaluation of two gliptins and their main impurities of synthesis.
  • Camila F A Giordani
  • Sarah Campanharo
  • Nathalie R Wingert
  • Lívia M Bueno
  • Joanna W Manoel
  • Barbara Costa
  • Shanda Cattani
  • Marcelo Dutra Arbo
  • Solange Cristina Garcia
  • Cássia Virginia Garcia
  • Nádia Maria Volpato
  • Elfrides Eva Scherman Schapoval
  • Martin Steppe
  • BMC Pharmacol Toxicol.2019 12;20(Suppl 1):82. 10.1186/s40360-019-0354-2. doi: 10.1186/s40360-019-0354-2.Epub 2019-12-19.

結核治療レジメンへの高用量イソニアジドの組み入れをガイドするためのイソニアジド耐性マーカーの同定：システマティックレビュー

Identifying isoniazid resistance markers to guide inclusion of high-dose isoniazid in tuberculosis treatment regimens: a systematic review.
  • Emmanuel Rivière
  • Michael G Whitfield
  • Jochem Nelen
  • Tim H Heupink
  • Annelies Van Rie
  • Clin. Microbiol. Infect..2020 Jul;S1198-743X(20)30387-6. doi: 10.1016/j.cmi.2020.07.004.Epub 2020-07-09.

機械学習とマルチパラメトリック脳MRIによる多発性硬化症とスフェロイドを伴う遺伝性びまん性白血病の鑑別

Machine Learning and Multiparametric Brain MRI to Differentiate Hereditary Diffuse Leukodystrophy with Spheroids from Multiple Sclerosis.
  • Gabriel Mangeat
  • Russell Ouellette
  • Maxime Wabartha
  • Benjamin De Leener
  • Michael Plattén
  • Virginija Danylaité Karrenbauer
  • Marcel Warntjes
  • Nikola Stikov
  • Caterina Mainero
  • Julien Cohen-Adad
  • Tobias Granberg
  • J Neuroimaging.2020 May;doi: 10.1111/jon.12725.Epub 2020-05-26.

フィブリノーゲンγ鎖ペプチド被覆、ADP カプセル化リポソームの心肺バイパス凝固症後の止血アジュバントとしての治療的可能性

Therapeutic potential of fibrinogen γ-chain peptide-coated, ADP-encapsulated liposomes as a haemostatic adjuvant for post-cardiopulmonary bypass coagulopathy.
  • Osamu Ishida
  • Kohsuke Hagisawa
  • Nozomu Yamanaka
  • Koji Tsutsumi
  • Hidenori Suzuki
  • Masato Takikawa
  • Shinji Takeoka
  • Manabu Kinoshita
  • Sci Rep.2020 Jul;10(1):11308. 10.1038/s41598-020-68307-5. doi: 10.1038/s41598-020-68307-5.Epub 2020-07-09.

フォークヘッドボックス（FOX）G1は、T-cell factor-4/β-カテニン/FOXG1複合体を形成し、Wntシグナルを活性化することで、肝細胞癌の上皮-間葉系転移を促進する

Forkhead box (FOX) G1 promotes hepatocellular carcinoma epithelial-Mesenchymal transition by activating Wnt signal through forming T-cell factor-4/Beta-catenin/FOXG1 complex.
  • Xingrong Zheng
  • Jiaxin Lin
  • Hewei Wu
  • Zhishuo Mo
  • Yunwen Lian
  • Peipei Wang
  • Zhaoxia Hu
  • Zhiliang Gao
  • Liang Peng
  • Chan Xie
  • J. Exp. Clin. Cancer Res..2019 Nov;38(1):475. 10.1186/s13046-019-1433-3. doi: 10.1186/s13046-019-1433-3.Epub 2019-11-27.

症候性脳転移を再発した患者における救済療法としてのベバシズマブをベースとした治療

Bevacizumab-based treatment as salvage therapy in patients with recurrent symptomatic brain metastases.
  • Anna Sophie Berghoff
  • Michael Oliver Breckwoldt
  • Lars Riedemann
  • Kianush Karimian-Jazi
  • Sarah Loew
  • Franziska Schlieter
  • Julia Furtner
  • Marc Cinci
  • Michael Thomas
  • Moritz J Strowitzki
  • Frederik Marmé
  • Laura L Michel
  • Thomas Schmidt
  • Dirk Jäger
  • Martin Bendszus
  • Matthias Preusser
  • Wolfgang Wick
  • Frank Winkler
  • Neurooncol Adv.2020 Jan-Dec;2(1):vdaa038. vdaa038. doi: 10.1093/noajnl/vdaa038.Epub 2020-03-16.

慢性疼痛を持つ児童・青少年に対するデジタルヘルス心理学的介入（WebMAP Mobile）：ハイブリッド有効性実施段階的ウェッジクラスター無作為化試験の結果

A digital health psychological intervention (WebMAP Mobile) for children and adolescents with chronic pain: results of a hybrid effectiveness-implementation stepped wedge cluster randomized trial.
  • Tonya M Palermo
  • Rocio de la Vega
  • Caitlin Murray
  • Emily Law
  • Chuan Zhou
  • Pain.2020 Jul;doi: 10.1097/j.pain.0000000000001994.Epub 2020-07-10.

新血管性加齢黄斑変性症におけるQoLに関して、ベバシズマブの6週および8週の注射頻度は、現在の4週の注射頻度よりも非劣性である：無作為化比較試験

Six and eight weeks injection frequencies of bevacizumab are non-inferior to the current four weeks injection frequency for quality of life in neovascular age-related macular degeneration: a randomized controlled trial.
  • Martijn S Visser
  • Sankha Amarakoon
  • Tom Missotten
  • Reinier Timman
  • Jan J V Busschbach
  • Qual Life Res.2020 Jul;10.1007/s11136-020-02580-9. doi: 10.1007/s11136-020-02580-9.Epub 2020-07-14.

アレルギー性鼻炎治療における間接灸の有効性と安全性．RCT のシステマティックレビューとメタアナリシスのためのプロトコル

Effectiveness and safety of indirect moxibustion for the treatment of allergic rhinitis: A protocol for systematic review and meta-analysis of RCTs.
  • Ting Yuan
  • Yong Fu
  • Jun Xiong
  • Haifeng Zhang
  • Jun Yang
  • Xue Wang
  • Hao Fan
  • Yunfeng Jiang
  • Xiaohong Zhou
  • Kai Liao
  • Lingling Xu
  • Medicine (Baltimore).2020 Jul;99(28):e20911. 00005792-202007100-00036. doi: 10.1097/MD.0000000000020911.

脊髄筋萎縮におけるヒト骨格筋線維におけるIバンドおよびMバンドからのSMNの誤局在化は、サルコメアの一次構造変化と関連している

Mislocalization of SMN from the I-band and M-band in human skeletal myofibers in spinal muscular atrophy associates with primary structural alterations of the sarcomere.
  • María T Berciano
  • María S Castillo-Iglesias
  • J Fernando Val-Bernal
  • Vanesa Lafarga
  • José C Rodriguez-Rey
  • Miguel Lafarga
  • Olga Tapia
  • Cell Tissue Res..2020 Jul;10.1007/s00441-020-03236-3. doi: 10.1007/s00441-020-03236-3.Epub 2020-07-16.

遺伝的変異は、血漿アンジオポエチン-2が急性腎障害のサブタイプの発生に関与していることを示唆している

Genetic variation implicates plasma angiopoietin-2 in the development of acute kidney injury sub-phenotypes.
  • Pavan K Bhatraju
  • Max Cohen
  • Ryan J Nagao
  • Eric D Morrell
  • Susanna Kosamo
  • Xin-Ya Chai
  • Robin Nance
  • Victoria Dmyterko
  • Joseph Delaney
  • Jason D Christie
  • Kathleen D Liu
  • Carmen Mikacenic
  • Sina A Gharib
  • W Conrad Liles
  • Ying Zheng
  • David C Christiani
  • Jonathan Himmelfarb
  • Mark M Wurfel
  • BMC Nephrol.2020 Jul;21(1):284. 10.1186/s12882-020-01935-1. doi: 10.1186/s12882-020-01935-1.Epub 2020-07-17.

原発性副甲状腺機能亢進症の骨粗鬆症患者におけるカルシウム、腎、および骨への影響に関する副甲状腺摘出術と比較したデノスマブの効果

Effects of denosumab as compared with parathyroidectomy regarding calcium, renal, and bone involvement in osteoporotic patients with primary hyperparathyroidism.
  • Daichi Miyaoka
  • Yasuo Imanishi
  • Eiko Kato
  • Norikazu Toi
  • Yuki Nagata
  • Masafumi Kurajoh
  • Shinsuke Yamada
  • Masaaki Inaba
  • Masanori Emoto
  • Endocrine.2020 Jul;10.1007/s12020-020-02401-6. doi: 10.1007/s12020-020-02401-6.Epub 2020-07-03.

危機的状況の中で必要な枠組みとしての障害者の権利 標準ケアと今後の医療のあり方

Disability Rights as a Necessary Framework for Crisis Standards of Care and the Future of Health Care.
  • Laura Guidry-Grimes
  • Katie Savin
  • Joseph A Stramondo
  • Joel Michael Reynolds
  • Marina Tsaplina
  • Teresa Blankmeyer Burke
  • Angela Ballantyne
  • Eva Feder Kittay
  • Devan Stahl
  • Jackie Leach Scully
  • Rosemarie Garland-Thomson
  • Anita Tarzian
  • Doron Dorfman
  • Joseph J Fins
  • Hastings Cent Rep.2020 May;50(3):28-32. doi: 10.1002/hast.1128.

培養哺乳類細胞において、Gタンパク質共役型受容体55アゴニストであるリゾホスファチジルイノシトールを生理活性モノアシルグリセロールに変換するエクト型ホスホリパーゼCとしてのヒトグリセロホスホジエステラーゼ3の同定

Identification of human glycerophosphodiesterase 3 as an ecto phospholipase C that converts the G protein-coupled receptor 55 agonist lysophosphatidylinositol to bioactive monoacylglycerols in cultured mammalian cells.
  • Toshihiko Tsutsumi
  • Risa Matsuda
  • Katsuya Morito
  • Kohei Kawabata
  • Miho Yokota
  • Miki Nikawadori
  • Manami Inoue-Fujiwara
  • Satoshi Kawashima
  • Mayumi Hidaka
  • Takenori Yamamoto
  • Naoshi Yamazaki
  • Tamotsu Tanaka
  • Yasuo Shinohara
  • Hiroyuki Nishi
  • Akira Tokumura
  • Biochim Biophys Acta Mol Cell Biol Lipids.2020 Jul;1865(9):158761. S1388-1981(20)30153-0. doi: 10.1016/j.bbalip.2020.158761.Epub 2020-07-03.

ミトコンドリア機能障害と高カルシウム負荷の組み合わせは、黒質ドーパミン作動性ニューロンの選択的喪失の背景にある抗酸化防御機能の低下をもたらします

Mitochondrial Dysfunction Combined with High Calcium Load Leads to Impaired Antioxidant Defense Underlying the Selective Loss of Nigral Dopaminergic Neurons.
  • Konrad M Ricke
  • Thomas Paß
  • Sammy Kimoloi
  • Kai Fährmann
  • Christian Jüngst
  • Astrid Schauss
  • Olivier R Baris
  • Marijana Aradjanski
  • Aleksandra Trifunovic
  • Therese M Eriksson Faelker
  • Matteo Bergami
  • Rudolf J Wiesner
  • J. Neurosci..2020 Feb;40(9):1975-1986. JNEUROSCI.1345-19.2019. doi: 10.1523/JNEUROSCI.1345-19.2019.Epub 2020-01-31.

COVID-19ウイルス由来RNA依存性RNAポリメラーゼの構造

Structure of the RNA-dependent RNA polymerase from COVID-19 virus.
  • Yan Gao
  • Liming Yan
  • Yucen Huang
  • Fengjiang Liu
  • Yao Zhao
  • Lin Cao
  • Tao Wang
  • Qianqian Sun
  • Zhenhua Ming
  • Lianqi Zhang
  • Ji Ge
  • Litao Zheng
  • Ying Zhang
  • Haofeng Wang
  • Yan Zhu
  • Chen Zhu
  • Tianyu Hu
  • Tian Hua
  • Bing Zhang
  • Xiuna Yang
  • Jun Li
  • Haitao Yang
  • Zhijie Liu
  • Wenqing Xu
  • Luke W Guddat
  • Quan Wang
  • Zhiyong Lou
  • Zihe Rao
  • Science.2020 05;368(6492):779-782. science.abb7498. doi: 10.1126/science.abb7498.Epub 2020-04-10.

レビー小体型認知症のサブタイプは、α-シヌクレインとタウの分布に関連している

Subtypes of dementia with Lewy bodies are associated with α-synuclein and tau distribution.
  • Tanis J Ferman
  • Naoya Aoki
  • Bradley F Boeve
  • Jeremiah A Aakre
  • Kejal Kantarci
  • Jonathan Graff-Radford
  • Joseph E Parisi
  • Jay A Van Gerpen
  • Neill R Graff-Radford
  • Ryan J Uitti
  • Otto Pedraza
  • Melissa E Murray
  • Zbigniew K Wszolek
  • R Ross Reichard
  • Julie A Fields
  • Owen A Ross
  • David S Knopman
  • Ronald C Petersen
  • Dennis W Dickson
  • Neurology.2020 Jul;95(2):e155-e165. WNL.0000000000009763. doi: 10.1212/WNL.0000000000009763.Epub 2020-06-19.

細菌ベンゾイルコエンザイムAリガーゼと植物III型ポリケチド合成酵素に由来する生理活性分子の化学酵素合成と生物学的評価

Chemoenzymatic Synthesis and Biological Evaluation for Bioactive Molecules Derived from Bacterial Benzoyl Coenzyme A Ligase and Plant Type III Polyketide Synthase.
  • Kamal Adhikari
  • I-Wen Lo
  • Chun-Liang Chen
  • Yung-Lin Wang
  • Kuan-Hung Lin
  • Saeid Malek Zadeh
  • Rajesh Rattinam
  • Yi-Shan Li
  • Chang-Jer Wu
  • Tsung-Lin Li
  • Biomolecules.2020 May;10(5). E738. doi: 10.3390/biom10050738.Epub 2020-05-09.

ストライプドキャットフィッシュ（Pangasianodon hypophthalmus）の頭部腎臓白血球に対するPhyllanthus amarusとPsidium guajavaの抽出物、画分および純粋な化合物の免疫調節能

Immunomodulatory potential of extracts, fractions and pure compounds from Phyllanthus amarus and Psidium guajava on striped catfish (Pangasianodon hypophthalmus) head kidney leukocytes.
  • Truong Quynh Nhu
  • Nguyen Phuc Dam
  • Bui Thi Bich Hang
  • Le Thi Bach
  • Do Thi Thanh Huong
  • Bui Thi Buu Hue
  • Marie-Louise Scippo
  • Nguyen Thanh Phuong
  • Joëlle Quetin-Leclercq
  • Patrick Kestemont
  • Fish Shellfish Immunol..2020 Jun;104:289-303. S1050-4648(20)30378-8. doi: 10.1016/j.fsi.2020.05.051.Epub 2020-06-13.

人間の採食の生活史。異文化と個体間の変動

The life history of human foraging: Cross-cultural and individual variation.
  • Jeremy Koster
  • Richard McElreath
  • Kim Hill
  • Douglas Yu
  • Glenn Shepard
  • Nathalie van Vliet
  • Michael Gurven
  • Benjamin Trumble
  • Rebecca Bliege Bird
  • Douglas Bird
  • Brian Codding
  • Lauren Coad
  • Luis Pacheco-Cobos
  • Bruce Winterhalder
  • Karen Lupo
  • Dave Schmitt
  • Paul Sillitoe
  • Margaret Franzen
  • Michael Alvard
  • Vivek Venkataraman
  • Thomas Kraft
  • Kirk Endicott
  • Stephen Beckerman
  • Stuart A Marks
  • Thomas Headland
  • Margaretha Pangau-Adam
  • Anders Siren
  • Karen Kramer
  • Russell Greaves
  • Victoria Reyes-García
  • Maximilien Guèze
  • Romain Duda
  • Álvaro Fernández-Llamazares
  • Sandrine Gallois
  • Lucentezza Napitupulu
  • Roy Ellen
  • John Ziker
  • Martin R Nielsen
  • Elspeth Ready
  • Christopher Healey
  • Cody Ross
  • Sci Adv.2020 Jun;6(26):eaax9070. aax9070. doi: 10.1126/sciadv.aax9070.Epub 2020-06-24.

ヒト骨髄腫におけるプロテアソーム阻害剤に対する抵抗性を克服するためのバイオマーカーおよび治療標的としてのMIF

MIF as a biomarker and therapeutic target for overcoming resistance to proteasome inhibitors in human myeloma.
  • Qiang Wang
  • Dongyu Zhao
  • Miao Xian
  • Zhuo Wang
  • Enguang Bi
  • Pan Su
  • Jianfei Qian
  • Xingzhe Ma
  • Maojie Yang
  • Lintao Liu
  • Youli Zu
  • Sai Ravi Pingali
  • Kaifu Chen
  • Zhen Cai
  • Qing Yi
  • Blood.2020 Jun;blood.2020005795. doi: 10.1182/blood.2020005795.Epub 2020-06-24.

エタノールによる条件付き場所選好性の消失と回復は、アストロサイトのシスチン-グルタミン酸アンチポーター含量の違いと関連していることが示唆された

Susceptibility to extinction and reinstatement of ethanol-induced conditioned place preference is related to differences in astrocyte cystine-glutamate antiporter content.
  • Vanessa Cristiane Santana Amaral
  • Gessynger Morais-Silva
  • Celina F Laverde
  • Marcelo T Marin
  • Neurosci. Res..2020 Jul;S0168-0102(20)30402-8. doi: 10.1016/j.neures.2020.07.002.Epub 2020-07-09.

病院排水中のアンピシリンを迅速かつ高感度に検出するための蛍光センサー支援紙ベースの競争的ラテラルフローイムノアッセイ

A Fluorescent Sensor-Assisted Paper-Based Competitive Lateral Flow Immunoassay for the Rapid and Sensitive Detection of Ampicillin in Hospital Wastewater.
  • Honggui Lin
  • Feixiang Fang
  • Jiahui Zang
  • Jianlong Su
  • Qingyuan Tian
  • Ranjith Kumar Kankala
  • Xuexia Lin
  • Micromachines (Basel).2020 Apr;11(4). E431. doi: 10.3390/mi11040431.Epub 2020-04-20.

βB1クリスタリンの凝集しやすい領域(APR)がアミロイド様構造を形成し、ヒト白内障眼水晶体から分離された可溶性タンパク質の凝集を誘導することを明らかにした

Predicted aggregation-prone region (APR) in βB1-crystallin forms the amyloid-like structure and induces aggregation of soluble proteins isolated from human cataractous eye lens.
  • Ram Swaroop Harsolia
  • Ambika Kanwar
  • Shalini Gour
  • Vijay Kumar
  • Vikas Kumar
  • Rati Bansal
  • Suman Kumar
  • Manish Singh
  • Jay Kant Yadav
  • Int. J. Biol. Macromol..2020 Jul;163:702-710. S0141-8130(20)33774-0. doi: 10.1016/j.ijbiomac.2020.07.028.Epub 2020-07-08.

急性呼吸窮迫症候群COVID-19患者におけるSARS-CoV-2特異的T細胞の表現型と動態

Phenotype and kinetics of SARS-CoV-2-specific T cells in COVID-19 patients with acute respiratory distress syndrome.
  • Daniela Weiskopf
  • Katharina S Schmitz
  • Matthijs P Raadsen
  • Alba Grifoni
  • Nisreen M A Okba
  • Henrik Endeman
  • Johannes P C van den Akker
  • Richard Molenkamp
  • Marion P G Koopmans
  • Eric C M van Gorp
  • Bart L Haagmans
  • Rik L de Swart
  • Alessandro Sette
  • Rory D de Vries
  • Sci Immunol.2020 06;5(48). eabd2071. doi: 10.1126/sciimmunol.abd2071.

本研究では、光の利用可能性に対する光合成的適応が、鉄分制限下での開花性シアノバクテリウムPseudanabaenaの生態学的成功を形作っていることを明らかにした

Photosynthetic adaptation to light availability shapes the ecological success of bloom-forming cyanobacterium Pseudanabaena to iron limitation.
  • Zheng-Ke Li
  • Guo-Zheng Dai
  • Yong Zhang
  • Kui Xu
  • Laura Bretherton
  • Zoe V Finkel
  • Andrew J Irwin
  • Philippe Juneau
  • Bao-Sheng Qiu
  • J. Phycol..2020 Jun;doi: 10.1111/jpy.13040.Epub 2020-06-18.

複雑な脊椎手術後の再手術と死亡率：Spine AdVerse Event Severity（SAVES）システムを用いた679例のプロスペクティブコホートにおける2年間の追跡調査

Revision surgery and mortality following complex spine surgery: 2-year follow-up in a prospective cohort of 679 patients using the Spine AdVerse Event Severity (SAVES) system.
  • Tanvir Johanning Bari
  • Sven Karstensen
  • Mathias Dahl Sørensen
  • Martin Gehrchen
  • John Street
  • Benny Dahl
  • Spine Deform.2020 Jun;10.1007/s43390-020-00164-8. doi: 10.1007/s43390-020-00164-8.Epub 2020-06-30.

新規ニトロインダゾール-ポルフィリン共役体の開発合成、特性評価および抗菌性

New nitroindazole-porphyrin conjugates: Synthesis, characterization and antibacterial properties.
  • Mohammed Eddahmi
  • Vera Sousa
  • Nuno M M Moura
  • Cristina J Dias
  • Latifa Bouissane
  • Maria A F Faustino
  • José A S Cavaleiro
  • Ana T P C Gomes
  • Adelaide Almeida
  • Maria G P M S Neves
  • El Mostapha Rakib
  • Bioorg. Chem..2020 Jun;101:103994. S0045-2068(20)31291-8. doi: 10.1016/j.bioorg.2020.103994.Epub 2020-06-03.

酪酸ナトリウムは、NRF2安定化を介した活性酸素レベルの調節により、高コレステロール誘発性の神経細胞アミロイド生成を抑制する：NOX2とSOD1の関与

Sodium butyrate inhibits high cholesterol-induced neuronal amyloidogenesis by modulating NRF2 stabilization-mediated ROS levels: involvement of NOX2 and SOD1.
  • Seo Yihl Kim
  • Chang Woo Chae
  • Hyun Jik Lee
  • Young Hyun Jung
  • Gee Euhn Choi
  • Jun Sung Kim
  • Jae Ryong Lim
  • Joo Eun Lee
  • Ji Hyeon Cho
  • Hansoo Park
  • Changho Park
  • Ho Jae Han
  • Cell Death Dis.2020 Jun;11(6):469. 10.1038/s41419-020-2663-1. doi: 10.1038/s41419-020-2663-1.Epub 2020-06-18.

Ibervillea sonorae抽出物に含まれるククルビタン型トリテルペンの定量分析。抗増殖活性との関連性の研究

Quantitative analysis of cucurbitane-type triterpenes in Ibervillea sonorae extracts: Relationship study with their antiproliferative activity.
  • Heriberto Torres Moreno
  • Federica Ianni
  • Ramón Enrique Robles Zepeda
  • Julio César López-Romero
  • Max Vidal-Gutiérrez
  • Melitza Dolores Jocobi Durán
  • Roberta Galarini
  • Emidio Camaioni
  • Roccaldo Sardella
  • Maria Carla Marcotullio
  • Steroids.2020 Jun;161:108676. S0039-128X(20)30102-1. doi: 10.1016/j.steroids.2020.108676.Epub 2020-06-06.

RPGR欠損Rd9マウスにおけるコドン最適化RPGRを発現するAAVベクターの毒性と薬理学

Toxicology and Pharmacology of an AAV Vector Expressing Codon-Optimized RPGR in RPGR-Deficient Rd9 Mice.
  • Chunjuan Song
  • Thomas J Conlon
  • Wen-Tao Deng
  • Kirsten E Coleman
  • Ping Zhu
  • Cayrn Plummer
  • Savitri Mandapati
  • Mailin Van Hoosear
  • Kari B Green
  • Peter Sonnentag
  • Alok K Sharma
  • Adrian Timmers
  • Paulette M Robinson
  • David R Knop
  • William W Hauswirth
  • Jeffrey D Chulay
  • Mark S Shearman
  • Guo-Jie Ye
  • Hum Gene Ther Clin Dev.2018 12;29(4):188-197. doi: 10.1089/humc.2018.168.

エベロリムスとタクロリムスの減量投与を受けたデノボ腎移植患者における免疫抑制剤関連有害事象のプロファイル

Immunosuppressive Drug-Associated Adverse Event Profiles in De Novo Kidney Transplant Recipients Receiving Everolimus and Reduced Tacrolimus Doses.
  • Tamiris Abait Miranda
  • Claudia Rosso Felipe
  • Renato Hideo Nakagawa Santos
  • Jose Osmar Medina Pestana
  • Helio Tedesco-Silva Junior
  • Ther Drug Monit.2020 Jul;doi: 10.1097/FTD.0000000000000790.Epub 2020-07-08.

エテン/1-ヘキセン共重合における「スパレック型」アンサ-ジルコノセンのコモノマー親和性チューニングの限界について：ハイスループット実験/QSAR法によるアプローチ

On the limits of tuning comonomer affinity of 'Spaleck-type' ansa-zirconocenes in ethene/1-hexene copolymerization: a high-throughput experimentation/QSAR approach.
  • Christian Ehm
  • Antonio Vittoria
  • Georgy P Goryunov
  • Vyatcheslav V Izmer
  • Dmitry S Kononovich
  • Oleg V Samsonov
  • Peter H M Budzelaar
  • Alexander Z Voskoboynikov
  • Vincenzo Busico
  • Dmitry V Uborsky
  • Roberta Cipullo
  • Dalton Trans.2020 Jul;doi: 10.1039/d0dt01967d.Epub 2020-07-14.

結核菌感染肺胞上皮細胞はHIF-1α-NOS2軸を介して樹状細胞の機能を調節している

Mycobacterium tuberculosis-infected alveolar epithelial cells modulate dendritic cell function through the HIF-1α-NOS2 axis.
  • Tamara Silva Rodrigues
  • Annie Rocio Piñeros Alvarez
  • Ana Flávia Gembre
  • Maria Fernanda Pereira de Araújo Demonte Forni
  • Bruno Marcel Silva de Melo
  • José Carlos Farias Alves Filho
  • Niels Olsen Saraiva Câmara
  • Vânia Luiza Deperon Bonato
  • J. Leukoc. Biol..2020 Jun;doi: 10.1002/JLB.3MA0520-113R.Epub 2020-06-18.

ナイジェリアの伝統的な発酵シリアル食品から分離された潜在的なプロバイオティクス酵母からの揮発性化合物とフィターゼの生産と特性評価

Production and characterization of volatile compounds and phytase from potentially probiotic yeasts isolated from traditional fermented cereal foods in Nigeria.
  • Omotade Richard Ogunremi
  • Renu Agrawal
  • Abiodun Sanni
  • J Genet Eng Biotechnol.2020 Jun;18(1):16. 10.1186/s43141-020-00031-z. doi: 10.1186/s43141-020-00031-z.Epub 2020-06-08.

STAT3遮断による放射線照射は、グリオーマ微小環境における樹状細胞-T細胞相互作用を誘発し、治療効果を高める

Radiation with STAT3 blockade triggers dendritic cell-T cell interactions in the glioma microenvironment and therapeutic efficacy.
  • Martina Ott
  • Cynthia Kassab
  • Anantha Marisetty
  • Yuuri Hashimoto
  • Jun Wei
  • Daniel B Zamler
  • Jia-Shiun Leu
  • Karl-Heinz Tomaszowski
  • Aria Sabbagh
  • Dexing Fang
  • Pravesh Gupta
  • Waldemar Priebe
  • Rafal Zielinski
  • Jared K Burks
  • James P Long
  • Ling-Yuan Kong
  • Gregory N Fuller
  • John F de Groot
  • Erik P Sulman
  • Amy B Heimberger
  • Clin. Cancer Res..2020 Jun;clincanres.4092.2019. doi: 10.1158/1078-0432.CCR-19-4092.Epub 2020-06-30.

リンチ様症候群患者の分子腫瘍検査により、子孫に伝わるミスマッチ修復遺伝子のde novoモザイクバリアントが明らかになった

Molecular tumor testing in patients with Lynch-like syndrome reveals a de novo mosaic variant of a mismatch repair gene transmitted to offspring.
  • Erell Guillerm
  • Magali Svrcek
  • Armelle Bardier-Dupas
  • Noémie Basset
  • Florence Coulet
  • Chrystelle Colas
  • Eur. J. Hum. Genet..2020 Jul;10.1038/s41431-020-0689-6. doi: 10.1038/s41431-020-0689-6.Epub 2020-07-16.

4次元分解能を有するピエゾ抵抗型Eスキンとしての非対称アルベオレートPMMA/MWCNTフィルムと運動方向と気流量の検出への応用

Unsymmetrical Alveolate PMMA/MWCNT Film as a Piezoresistive E-Skin with Four-Dimensional Resolution and Application for Detecting Motion Direction and Airflow Rate.
  • Duo Chen
  • Zhen Liu
  • Yang Li
  • Dehui Sun
  • Xiaoyan Liu
  • Jinbo Pang
  • Hong Liu
  • Weijia Zhou
  • ACS Appl Mater Interfaces.2020 Jul;12(27):30896-30904. doi: 10.1021/acsami.0c02640.Epub 2020-06-23.

頭頸部地区における経口的ロボット手術：単一施設で治療を受けた67例の患者を対象としたレトロスペクティブ研究

Transoral robotic surgery in head and neck district: a retrospective study on 67 patients treated in a single center.
  • Fraco Ionna
  • Agostino Guida
  • Luigi Califano
  • Gaetano Motta
  • Giovanni Salzano
  • Ettore Pavone
  • Corrado Aversa
  • Francesco Longo
  • Salvatore Villano
  • Ludovica Marcella Ponzo
  • Pierluigi Franco
  • Simona Losito
  • Franco Maria Buonaguro
  • Maria Lina Tornesello
  • Maria Grazia Maglione
  • Infect. Agents Cancer.2020;15:40. 306. doi: 10.1186/s13027-020-00306-7.Epub 2020-06-15.

コロナウイルス疾患2019（COVID-19）における重症化の危険因子としてのCD4/CD8比の増加：レトロスペクティブ多施設共同研究

Increased CD4/CD8 ratio as a risk factor for critical illness in coronavirus disease 2019 (COVID-19): a retrospective multicentre study.
  • Carlo Pallotto
  • Lorenzo Roberto Suardi
  • Sara Esperti
  • Roberto Tarquini
  • Elisa Grifoni
  • Simone Meini
  • Alice Valoriani
  • Stefania Di Martino
  • Francesco Cei
  • Eleonora Sisti
  • Fiorella Piani
  • Annarita Botta
  • Elena Salomoni
  • Filippo Baragli
  • Pierluigi Blanc
  • Infect Dis (Lond).2020 09;52(9):675-677. doi: 10.1080/23744235.2020.1778178.Epub 2020-06-16.

異なる治療法を用いた T2N0M0 喉頭扁平上皮癌の長期治療成績の比較

Comparison of long-term treatment outcomes of T2N0M0 laryngeal squamous cell carcinoma using different treatment methods.
  • Eun Kyung Jung
  • Seong-Min Jin
  • Jae-Gu Kim
  • Jae-Uk Jung
  • Dong Hoon Lee
  • Joon Kyoo Lee
  • Sang Chul Lim
  • Woong-Ki Chung
  • Hee Kyung Kim
  • Jun-Eul Hwang
  • Hyun-Jeong Shim
  • Woo-Kyun Bae
  • Sang-Hee Cho
  • Ik-Joo Chung
  • Tae Mi Yoon
  • Oncol Lett.2020 Jul;20(1):921-930. OL-0-0-11628. doi: 10.3892/ol.2020.11628.Epub 2020-05-14.

肝移植後の患者における初期の移植片障害の有病率に対するレミフェンタニル対フェンタニルの前処置効果。ランダム化臨床試験

Preconditioning Effect of Remifentanil Versus Fentanyl in Prevalence of Early Graft Dysfunction in Patients After Liver Transplant: A Randomized Clinical Trial.
  • Sanaz Jowkar
  • Mohammad Bagher Khosravi
  • Mohammad Ali Sahmeddini
  • Mohammad Hossein Eghbal
  • Kazem Samadi
  • Exp Clin Transplant.2020 Jul;doi: 10.6002/ect.2019.0014.Epub 2020-07-06.

実験室スケールのチーズ製造におけるクレッツェンツァタイプのチーズを製造するための再結合乳の応用。技術と感覚的特性への影響

Application of Recombined Milk to Produce Crescenza-Type Cheese in Laboratory-Scale Cheesemaking: Implications on Technology and Sensory Properties.
  • Flavio Tidona
  • Salvatore Francolino
  • Roberta Ghiglietti
  • Francesco Locci
  • Gianluca Brusa
  • Marcello Alinovi
  • Germano Mucchetti
  • Giorgio Giraffa
  • Foods.2020 Jul;9(7). E928. doi: 10.3390/foods9070928.Epub 2020-07-14.

進行喉頭癌における甲状腺浸潤の発生率と疾患特異的生存への影響；第三次医療センターにおけるレトロスペクティブレビュー

Incidence of thyroid gland invasion in advanced laryngeal cancers and its impact on disease-specific survival; a retrospective review at a tertiary care center.
  • Tahir Muhammad
  • Rahim Dhanani
  • Sameen Mohtasham
  • Muntazir Hussain
  • Muhammad Faisal
  • Kashif Iqbal Malik
  • Arif Jamshed
  • Raza Hussain
  • Acta Otolaryngol..2020 Jul;:1-8. doi: 10.1080/00016489.2020.1778786.Epub 2020-07-07.

小児閉塞性睡眠時無呼吸症候群の解剖学的危険因子の評価における磁気共鳴イメージング：パイロット研究

Magnetic resonance imaging in the evaluation of anatomical risk factors for pediatric obstructive sleep apnoea-hypopnoea: a pilot study.
  • Salvatore Cappabianca
  • Francesco Iaselli
  • Alberto Negro
  • Angelo Basile
  • Alfonso Reginelli
  • Roberto Grassi
  • Antonio Rotondo
  • Int. J. Pediatr. Otorhinolaryngol..2013 Jan;77(1):69-75. S0165-5876(12)00544-7. doi: 10.1016/j.ijporl.2012.09.035.Epub 2012-10-12.

DTIトラクトベースの定量的感受性マッピング。回転不変の定量的尺度を用いた自己臍帯血細胞療法中の脳性麻痺患者の脳接続性変化における髄膜形成の潜在的な役割を調査するための初期フィージビリティスタディ

DTI Tract-Based Quantitative Susceptibility Mapping: An Initial Feasibility Study to Investigate the Potential Role of Myelination in Brain Connectivity Change in Cerebral Palsy Patients During Autologous Cord Blood Cell Therapy Using a Rotationally-Invariant Quantitative Measure.
  • Lijia Zhang
  • Susan Ellor
  • Jessica M Sun
  • Chunlei Liu
  • Joanne Kurtzburg
  • Allen W Song
  • J Magn Reson Imaging.2020 Jul;:e27286. doi: 10.1002/jmri.27286.Epub 2020-07-16.

グルタチオン：カドミウム曝露シロイヌナズナにおける金属キレーション、栄養の恒常性、細胞周期の調節、DNA損傷応答における重要な役割を果たす

Glutathione: A key player in metal chelation, nutrient homeostasis, cell cycle regulation and the DNA damage response in cadmium-exposed Arabidopsis thaliana.
  • Sophie Hendrix
  • Marijke Jozefczak
  • Małgorzata Wójcik
  • Jana Deckers
  • Jaco Vangronsveld
  • Ann Cuypers
  • Plant Physiol. Biochem..2020 Jun;154:498-507. S0981-9428(20)30281-3. doi: 10.1016/j.plaphy.2020.06.006.Epub 2020-06-27.

また、がん細胞由来の小細胞外小胞に存在するαvβ6インテグリンは血管新生を促進することが示唆された

The αvβ6 integrin in cancer cell-derived small extracellular vesicles enhances angiogenesis.
  • Shiv Ram Krishn
  • Israa Salem
  • Fabio Quaglia
  • Nicole M Naranjo
  • Ekta Agarwal
  • Qin Liu
  • Srawasti Sarker
  • Jessica Kopenhaver
  • Peter A McCue
  • Paul H Weinreb
  • Shelia M Violette
  • Dario C Altieri
  • Lucia R Languino
  • J Extracell Vesicles.2020;9(1):1763594. 1763594. doi: 10.1080/20013078.2020.1763594.Epub 2020-05-20.

非小細胞肺がんにおけるニボルマブ曝露と治療成績の相関

Correlation between nivolumab exposure and treatment outcomes in non-small-cell lung cancer.
  • Edwin A Basak
  • Stijn L W Koolen
  • Daan P Hurkmans
  • Marco W J Schreurs
  • Sander Bins
  • Esther Oomen-de Hoop
  • Annemarie J M Wijkhuijs
  • Ilse den Besten
  • Stefan Sleijfer
  • Reno Debets
  • Astrid A M van der Veldt
  • Joachim G J V Aerts
  • Ron H J Mathijssen
  • Eur. J. Cancer.2019 03;109:12-20. S0959-8049(18)31554-5. doi: 10.1016/j.ejca.2018.12.008.Epub 2019-01-14.

ポリアミン修飾フラボノイドとウシ血清アルブミン（BSA）との相互作用の分光学的手法と分子シミュレーションによる検討

Investigation of the interaction of a polyamine-modified flavonoid with bovine serum albumin (BSA) by spectroscopic methods and molecular simulation.
  • Zhiyong Tian
  • Luyao Tian
  • Man Shi
  • Sihan Zhao
  • Shudi Guo
  • Wen Luo
  • Chaojie Wang
  • Zhihui Tian
  • J. Photochem. Photobiol. B, Biol..2020 May;209:111917. S1011-1344(20)30367-5. doi: 10.1016/j.jphotobiol.2020.111917.Epub 2020-05-28.

壊滅的な小児てんかんの保護または感受性。ノーディング症候群はHLA結合溝の免疫遺伝学的フィンガープリントと関連している

Protection or susceptibility to devastating childhood epilepsy: Nodding Syndrome associates with immunogenetic fingerprints in the HLA binding groove.
  • Gil Benedek
  • Mahmoud Abed El Latif
  • Keren Miller
  • Mila Rivkin
  • Ally Ahmed Ramadhan Lasu
  • Lul P Riek
  • Richard Lako
  • Shimon Edvardson
  • Sagit-Arbel Alon
  • Eithan Galun
  • Mia Levite
  • PLoS Negl Trop Dis.2020 Jul;14(7):e0008436. PNTD-D-20-00136. doi: 10.1371/journal.pntd.0008436.Epub 2020-07-08.

PD-L1陽性進行非小細胞肺癌患者におけるニボルマブ＋イピリムマブと既存の免疫療法との比較。システマティックレビューとネットワークメタアナリシス

Nivolumab plus Ipilimumab versus Existing Immunotherapies in Patients with PD-L1-Positive Advanced Non-Small Cell Lung Cancer: A Systematic Review and Network Meta-Analysis.
  • Koichi Ando
  • Yasunari Kishino
  • Tetsuya Homma
  • Sojiro Kusumoto
  • Toshimitsu Yamaoka
  • Akihiko Tanaka
  • Tohru Ohmori
  • Tsukasa Ohnishi
  • Hironori Sagara
  • Cancers (Basel).2020 Jul;12(7). E1905. doi: 10.3390/cancers12071905.Epub 2020-07-15.

次世代シークエンシングオフターゲットデータを用いた薬理遺伝学的バリアントの同定のための新しいアプローチ

A Novel Approach for the Identification of Pharmacogenetic Variants in through Next-Generation Sequencing Off-Target Data.
  • Javier Lanillos
  • María Santos
  • Marta Carcajona
  • Juan María Roldan-Romero
  • Angel M Martinez
  • Bruna Calsina
  • María Monteagudo
  • Luis Javier Leandro-García
  • Cristina Montero-Conde
  • Alberto Cascón
  • Paolo Maietta
  • Sara Alvarez
  • Mercedes Robledo
  • Cristina Rodriguez-Antona
  • J Clin Med.2020 Jul;9(7). E2082. doi: 10.3390/jcm9072082.Epub 2020-07-02.

ラット頸動脈の臓器培養における高度な糖化最終生成物の長期投与によるノルアドレナリン誘発性収縮の抑制のメカニズム

Mechanisms underlying suppression of noradrenaline-induced contraction by prolonged treatment with advanced glycation end-products in organ-cultured rat carotid artery.
  • Takayuki Matsumoto
  • Keisuke Takayanagi
  • Mihoka Kojima
  • Kumiko Taguchi
  • Tsuneo Kobayashi
  • Pflugers Arch..2020 03;472(3):355-366. 10.1007/s00424-020-02349-6. doi: 10.1007/s00424-020-02349-6.Epub 2020-01-18.

ダニ媒介性脳炎（TBE）の症例はランダムではない：オーストリアのTBE時系列に基づいたトレンド、低頻度および高頻度の振動を説明する

Tick-borne encephalitis (TBE) cases are not random: explaining trend, low- and high-frequency oscillations based on the Austrian TBE time series.
  • Franz Rubel
  • Melanie Walter
  • Janna R Vogelgesang
  • Katharina Brugger
  • BMC Infect. Dis..2020 Jun;20(1):448. 10.1186/s12879-020-05156-7. doi: 10.1186/s12879-020-05156-7.Epub 2020-06-26.

焦点性細分化糸球体硬化症および微小変化疾患に対するアバタセプト治療の有効性．A systematic review of case reports, case series, and observational studies"Zp_2029"

Efficacy of abatacept treatment for focal segmental glomerulosclerosis and minimal change disease: A systematic review of case reports, case series, and observational studies
.
  • Panupong Hansrivijit
  • Max M Puthenpura
  • Nasrollah Ghahramani
  • Clin. Nephrol..2020 Jun;186810. doi: 10.5414/CN110134.Epub 2020-06-26.

高比表面積を有するKOH活性多孔質バイオ炭による水中の六価クロム及びナフタレンの吸着除去。その影響因子、メカニズム、再利用性の検討

KOH-activated porous biochar with high specific surface area for adsorptive removal of chromium (VI) and naphthalene from water: Affecting factors, mechanisms and reusability exploration.
  • Jianhua Qu
  • Yuxin Wang
  • Xue Tian
  • Zhao Jiang
  • Fengxia Deng
  • Yue Tao
  • Qun Jiang
  • Lei Wang
  • Ying Zhang
  • J. Hazard. Mater..2020 Jun;401:123292. S0304-3894(20)31281-4. doi: 10.1016/j.jhazmat.2020.123292.Epub 2020-06-23.

低密度リポ蛋白コレステロール低下を予測する間接反応モデルを用いた健康なボランティアまたは高コレステロール血症患者におけるアリロクマブの母集団薬物動態/薬力学的解析。生物学的製剤許可申請のためのサポート。第二部

Population Pharmacokinetic/Pharmacodynamic Analysis of Alirocumab in Healthy Volunteers or Hypercholesterolemic Subjects Using an Indirect Response Model to Predict Low-Density Lipoprotein Cholesterol Lowering: Support for a Biologics License Application Submission: Part II.
  • Xavier Nicolas
  • Nassim Djebli
  • Clémence Rauch
  • Aurélie Brunet
  • Fabrice Hurbin
  • Jean-Marie Martinez
  • David Fabre
  • Clin Pharmacokinet.2019 01;58(1):115-130. 10.1007/s40262-018-0670-5. doi: 10.1007/s40262-018-0670-5.

let-7iおよびmiR-192の発現は、喉頭および咽頭下咽頭癌患者におけるシスプラチンベースの化学放射線療法に対する抵抗性と関連していた

Expression of let-7i and miR-192 is associated with resistance to cisplatin-based chemoradiotherapy in patients with larynx and hypopharynx cancer.
  • Dennis Poel
  • François Rustenburg
  • Daoud Sie
  • Hendrik F van Essen
  • Paul P Eijk
  • Elisabeth Bloemena
  • Teresita Elhorst Benites
  • Madeleine C van den Berg
  • Marije R Vergeer
  • René C Leemans
  • Tineke E Buffart
  • Bauke Ylstra
  • Ruud H Brakenhoff
  • Henk M Verheul
  • Jens Voortman
  • Oral Oncol..2020 Jun;109:104851. S1368-8375(20)30287-6. doi: 10.1016/j.oraloncology.2020.104851.Epub 2020-06-22.

プロバイダーに焦点を当てた教育ツールキットを使用することで、患者のオピオイドへの曝露をさらに減らすための回復プログラムの強化を支援することができる

Using provider-focused education toolkits can aid enhanced recovery programs to further reduce patient exposure to opioids.
  • Ankit Sarin
  • Elizabeth Lancaster
  • Lee-Lynn Chen
  • Sima Porten
  • Lee-May Chen
  • Jeanette Lager
  • Elizabeth Wick
  • Perioper Med (Lond).2020;9:21. 153. doi: 10.1186/s13741-020-00153-5.Epub 2020-07-09.

限局性免疫グロブリン軽鎖アミロイドーシス：局所進行の予後因子を含む新規な知見

Localized immunoglobulin light chain amyloidosis: novel insights including prognostic factors for local progression.
  • Marco Basset
  • Kamal Hummedah
  • Christoph Kimmich
  • Kaya Veelken
  • Tobias Dittrich
  • Simone Brandelik
  • Michael Kreuter
  • Jessica Hassel
  • Nikolaus Bosch
  • Christiane Stuhlmann-Laeisz
  • Norbert Blank
  • Carsten Müller-Tidow
  • Christoph Röcken
  • Ute Hegenbart
  • Stefan Schönland
  • Am. J. Hematol..2020 Jun;doi: 10.1002/ajh.25915.Epub 2020-06-29.

Bliss'とLoeweのAMA1-RON2L、RH5、RIPRおよびCyRPA抗体の組み合わせによるマラリア原虫増殖抑制における相加的および相乗的効果

Bliss' and Loewe's additive and synergistic effects in Plasmodium falciparum growth inhibition by AMA1-RON2L, RH5, RIPR and CyRPA antibody combinations.
  • Yvonne Azasi
  • Shannon K Gallagher
  • Ababacar Diouf
  • Rebecca A Dabbs
  • Jing Jin
  • Syed Yusuf Mian
  • David L Narum
  • Carole A Long
  • Deepak Gaur
  • Simon J Draper
  • Michael P Fay
  • Louis H Miller
  • Kazutoyo Miura
  • Sci Rep.2020 Jul;10(1):11802. 10.1038/s41598-020-67877-8. doi: 10.1038/s41598-020-67877-8.Epub 2020-07-16.

養子縁組のデザインを用いて、家庭環境の影響に反応して子どもの行動問題のリスクの遺伝的差異を検定した

Using an adoption design to test genetically based differences in risk for child behavior problems in response to home environmental influences.
  • Robyn A Cree
  • Chang Liu
  • Ralitza Gueorguieva
  • Jenae M Neiderhiser
  • Leslie D Leve
  • Christian M Connell
  • Daniel S Shaw
  • Misaki N Natsuaki
  • Jody M Ganiban
  • Charles Beekman
  • Megan V Smith
  • David Reiss
  • Dev. Psychopathol..2020 Jul;:1-19. S0954579420000450. doi: 10.1017/S0954579420000450.Epub 2020-07-13.

穀物中のフェノキシカルボン酸除草剤の選択的同時抽出と分析を目的とした多層カーボンナノチューブをベースとした磁性ダミーテンプレート型分子インプリントポリマー（mag-MWCNTs-DMIPs）を開発した

Magnetic dummy-template molecularly imprinted polymers based on multi-walled carbon nanotubes for simultaneous selective extraction and analysis of phenoxy carboxylic acid herbicides in cereals.
  • Xucan Yuan
  • Yunxia Yuan
  • Xun Gao
  • Zhili Xiong
  • Longshan Zhao
  • Food Chem.2020 Jul;333:127540. S0308-8146(20)31402-3. doi: 10.1016/j.foodchem.2020.127540.Epub 2020-07-10.

タクロリムスの薬物動態および高速タクロリムス代謝における個体内および個体間の高いばらつきが固形臓器移植患者の転帰に及ぼす影響

Impacts of High Intra- and Inter-Individual Variability in Tacrolimus Pharmacokinetics and Fast Tacrolimus Metabolism on Outcomes of Solid Organ Transplant Recipients.
  • Charat Thongprayoon
  • Panupong Hansrivijit
  • Karthik Kovvuru
  • Swetha R Kanduri
  • Tarun Bathini
  • Aleksandra Pivovarova
  • Justin R Smith
  • Wisit Cheungpasitporn
  • J Clin Med.2020 Jul;9(7). E2193. doi: 10.3390/jcm9072193.Epub 2020-07-11.

尿中のビスフェノールAをトリメチルシリル誘導体の形で、単一四重極を用いたGC/MSで測定するための簡便で安価な非酵素的マイクロ波アシスト法を開発しました

A simple, inexpensive, non-enzymatic microwave-assisted method for determining bisphenol-A in urine in the form of trimethylsilyl derivative by GC/MS with single quadrupole.
  • N Yu Polovkov
  • J E Starkova
  • R S Borisov
  • J Pharm Biomed Anal.2020 Jun;188:113417. S0731-7085(20)31303-0. doi: 10.1016/j.jpba.2020.113417.Epub 2020-06-11.

馬山湾の堆積物に関連した潜在的な毒性学的影響を特徴づけるための複数のバイオアッセイ、標的および非標的解析。AhR介在性に着目した

Multiple Bioassays and Targeted and Nontargeted Analyses to Characterize Potential Toxicological Effects Associated with Sediments of Masan Bay: Focusing on AhR-Mediated Potency.
  • Junghyun Lee
  • Seongjin Hong
  • Taewoo Kim
  • Changkeun Lee
  • Seong-Ah An
  • Bong-Oh Kwon
  • Sunggyu Lee
  • Hyo-Bang Moon
  • John P Giesy
  • Jong Seong Khim
  • Environ. Sci. Technol..2020 04;54(7):4443-4454. doi: 10.1021/acs.est.9b07390.Epub 2020-03-23.

生体外体外膜酸素化回路における高酸素の炎症および血小板反応への影響

The effect of hyperoxia on inflammation and platelet responses in an ex vivo extracorporeal membrane oxygenation circuit.
  • Margaret R Passmore
  • Katrina K Ki
  • Chris Hh Chan
  • Talvin Lee
  • Mahé Bouquet
  • Emily S Wood
  • Sainath Raman
  • Sacha Rozencwajg
  • Aidan Jc Burrell
  • Charles I McDonald
  • Daman Langguth
  • Kiran Shekar
  • Maximilian V Malfertheiner
  • John F Fraser
  • Jacky Y Suen
  • Artif Organs.2020 Jul;doi: 10.1111/aor.13771.Epub 2020-07-09.

糞便マイクロバイオータ移植は、腹部膨満感が優勢な過敏性腸症候群の一部の患者の症状を軽減する。プラセボ対照無作為化試験の短期および長期結果

Fecal Microbiota Transplantation Reduces Symptoms in Some Patients With Irritable Bowel Syndrome with Predominant Abdominal Bloating: Short- and Long-Term Results from a Placebo-Controlled Randomized Trial.
  • Tom Holvoet
  • Marie Joossens
  • Jorge F Vázquez-Castellanos
  • Evelien Christiaens
  • Lander Heyerick
  • Jerina Boelens
  • Bruno Verhasselt
  • Hans van Vlierberghe
  • Martine De Vos
  • Jeroen Raes
  • Danny De Looze
  • Gastroenterology.2020 Jul;S0016-5085(20)34937-4. doi: 10.1053/j.gastro.2020.07.013.Epub 2020-07-15.

アマゾンのネイティブアメリカン集団における急性リンパ芽球性白血病の毒性に関連する薬理遺伝学的マーカーの特性化

Characterization of pharmacogenetic markers related to Acute Lymphoblastic Leukemia toxicity in Amazonian native Americans population.
  • Darlen Cardoso de Carvalho
  • Alayde Vieira Wanderley
  • André Mauricio Ribeiro Dos Santos
  • Fabiano Cordeiro Moreira
  • Roberta Borges Andrade de Sá
  • Marianne Rodrigues Fernandes
  • Antonio André Conde Modesto
  • Tatiane Piedade de Souza
  • Amanda Cohen-Paes
  • Luciana Pereira Colares Leitão
  • Juliana Carla Gomes Rodrigues
  • Artur Luiz da Costa da Silva
  • João Farias Guerreiro
  • Sidney Santos
  • André Salim Khayat
  • Paulo Pimentel de Assumpção
  • Ney Pereira Carneiro Dos Santos
  • Sci Rep.2020 Jun;10(1):10292. 10.1038/s41598-020-67312-y. doi: 10.1038/s41598-020-67312-y.Epub 2020-06-24.

中国湖北省の乳牛群におけるブルセラ症の有病率と発生率の測定における血清 ELISA に代わる乳中 ELISA の評価

Evaluation of a milk ELISA as an alternative to a serum ELISA in the determination of the prevalence and incidence of brucellosis in dairy herds in Hubei Province, China.
  • Yu Wang
  • Ian D Robertson
  • Shuang Cheng
  • Yan Wang
  • Liyue Hou
  • Guiqiang Wang
  • Xijuan Wu
  • Xiang Li
  • Yingyu Chen
  • Aizhen Guo
  • Prev. Vet. Med..2020 Jul;182:105086. S0167-5877(20)30057-X. doi: 10.1016/j.prevetmed.2020.105086.Epub 2020-07-01.

心不全におけるナトリウムグルコースコトランスポーター-2阻害薬：血糖コントロールを超えて。欧州心臓病学会心不全協会のポジションペーパー

Sodium glucose co-transporter-2 inhibitors in heart failure: beyond glycaemic control. The Position Paper of the Heart Failure Association of the European Society of Cardiology.
  • Petar M Seferović
  • Gabriele Fragasso
  • Mark Petrie
  • Wilfried Mullens
  • Roberto Ferrari
  • Thomas Thum
  • Johann Bauersachs
  • Stefan D Anker
  • Robin Ray
  • Yuksel Çavuşoğlu
  • Marija Polovina
  • Marco Metra
  • Giuseppe Ambrosio
  • Krishna Prasad
  • Jelena Seferović
  • Pardeep S Jhund
  • Giuseppe Dattilo
  • Jelena Čelutkiene
  • Massimo Piepoli
  • Brenda Moura
  • Ovidiu Chioncel
  • Tuvia Ben Gal
  • Stefan Heymans
  • Rudolf A De Boer
  • Tiny Jaarsma
  • Loreena Hill
  • Yuri Lopatin
  • Alexander R Lyon
  • Piotr Ponikowski
  • Mitja Lainščak
  • Ewa Jankowska
  • Christian Mueller
  • Francesco Cosentino
  • Lars Lund
  • Gerasimos S Filippatos
  • Frank Ruschitzka
  • Andrew J S Coats
  • Giuseppe M C Rosano
  • Eur. J. Heart Fail..2020 Jul;doi: 10.1002/ejhf.1954.Epub 2020-07-02.

2つの細胞株におけるフラビウイルス産生の比較特性。ヒト肝腫由来のHuh7.5.1-8とアフリカ緑猿腎臓由来のVero

Comparative characterization of flavivirus production in two cell lines: Human hepatoma-derived Huh7.5.1-8 and African green monkey kidney-derived Vero.
  • Kyoko Saito
  • Masayoshi Fukasawa
  • Yoshitaka Shirasago
  • Ryosuke Suzuki
  • Naoki Osada
  • Toshiyuki Yamaji
  • Takaji Wakita
  • Eiji Konishi
  • Kentaro Hanada
  • PLoS ONE.2020;15(4):e0232274. PONE-D-19-32355. doi: 10.1371/journal.pone.0232274.Epub 2020-04-24.

大腸発がん物質による標的特異的小核誘導：2-アミノ-1-メチル-6-フェニルイミダゾ4,5-ブピリジンと1,2-ジメチルヒドラジン

Target-specific micronucleus induction by colon carcinogens: 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and 1,2-dimethylhydrazine.
  • Hisako Hori
  • Satomi Shimoyoshi
  • Yasuhiro Tanaka
  • Wataru Fujii
  • Yoshinori Kitagawa
  • Makoto Hayashi
  • Regul. Toxicol. Pharmacol..2020 Apr;112:104578. S0273-2300(20)30004-0. doi: 10.1016/j.yrtph.2020.104578.Epub 2020-01-11.

日本人成人における食事性Na-K比と心血管疾患リスク因子：国民健康・栄養調査（2003年～2017年）のプールデータを用いたレトロスペクティブ横断的研究

Dietary sodium-to-potassium ratio and cardiovascular disease risk factors among Japanese adults: a retrospective cross-sectional study of pooled data from the National Health and Nutrition Survey, 2003-2017.
  • Emiko Okada
  • Chika Okada
  • Mai Matsumoto
  • Aya Fujiwara
  • Hidemi Takimoto
  • Br. J. Nutr..2020 Jul;:1-30. S000711452000269X. doi: 10.1017/S000711452000269X.Epub 2020-07-17.

Cyp1b1は、周産期肝臓におけるSrebp媒介のコレステロールおよびレチノイド合成を指示する；胎児発生時のレチノイン酸活性との関連

Cyp1b1 directs Srebp-mediated cholesterol and retinoid synthesis in perinatal liver; Association with retinoic acid activity during fetal development.
  • Meghan Maguire
  • Michele Campaigne Larsen
  • Chad M Vezina
  • Loredana Quadro
  • Youn-Kyung Kim
  • Sherry A Tanumihardjo
  • Colin R Jefcoate
  • PLoS ONE.2020;15(2):e0228436. PONE-D-18-08045. doi: 10.1371/journal.pone.0228436.Epub 2020-02-06.

ドイツで分離されたSpartina mottle virusの完全なゲノム配列から，Potyviridae（ポチウイルス科）の属名「Sparmovirus」に分類されることが明らかになった．

Complete genome sequence of a German isolate of spartina mottle virus supports its classification as a member of the proposed genus "Sparmovirus" within the family Potyviridae.
  • H Rose
  • W Menzel
  • D Knierim
  • F Rabenstein
  • Edgar Maiss
  • Arch. Virol..2020 Jul;10.1007/s00705-020-04726-z. doi: 10.1007/s00705-020-04726-z.Epub 2020-07-09.

メトホルミンのハロゲン化スルホンアミド誘導体の効果的な細胞輸送は、MCF-7細胞における抗増殖活性の向上とアポトーシス誘導に関連している

Effective Cellular Transport of -Halogenated Sulfonamide Derivatives of Metformin Is Related to Improved Antiproliferative Activity and Apoptosis Induction in MCF-7 Cells.
  • Magdalena Markowicz-Piasecka
  • Ibrahim Komeil
  • Johanna Huttunen
  • Joanna Sikora
  • Kristiina M Huttunen
  • Int J Mol Sci.2020 Mar;21(7). E2389. doi: 10.3390/ijms21072389.Epub 2020-03-30.

ミクソスポアレス感染に対するオリゴチャイテの免疫応答のトランスクリプトーム解析ミクソスポレウス属に感染したBranchiura sowerbyi

Transcriptomic analysis of oligochaete immune responses to myxosporeans infection: Branchiura sowerbyi infected with Myxobolus cultus.
  • Yuanli Zhao
  • Xinhua Liu
  • Bingwen Xi
  • Qianqian Zhang
  • Aihua Li
  • Jinyong Zhang
  • J. Invertebr. Pathol..2020 Jan;169:107283. S0022-2011(19)30184-3. doi: 10.1016/j.jip.2019.107283.Epub 2019-11-22.

SiPP（妊娠中および産後の脳卒中）。妊娠中および出産後の女性における脳血管疾患の病態生理学的メカニズム、臨床プロファイル、管理、転帰に関する前向き、観察的、国際的、多施設共同研究

SiPP (Stroke in Pregnancy and Postpartum): A prospective, observational, international, multicentre study on pathophysiological mechanisms, clinical profile, management and outcome of cerebrovascular diseases in pregnant and postpartum women.
  • Svetlana Lorenzano
  • Christine Kremer
  • Aleksandra Pavlovic
  • Dejana R Jovanovic
  • Else Charlotte Sandset
  • Hanne Christensen
  • Cheryl Bushnell
  • Anita Arsovska
  • Nikola Sprigg
  • Christine Roffe
  • Petra Ijäs
  • Zuzana Gdovinova
  • Anne Alexandrov
  • Marialuisa Zedde
  • Rossana Tassi
  • Monica Acciaresi
  • Maria Lantz
  • Katharina Sunnerhagen
  • Marija Zarkov
  • Kirsi Rantanen
  • Fabienne Perren
  • Helle K Iversen
  • Christina Kruuse
  • Agnieszka Slowik
  • Paola Palazzo
  • Janika Korv
  • Annette Fromm
  • Arijana Lovrencic-Huzjan
  • Eleni Korompoki
  • Ana Catarina Fonseca
  • Seana L Gall
  • Freimuth Brunner
  • Valeria Caso
  • Simona Sacco
  • Eur Stroke J.2020 Jun;5(2):193-203. 10.1177_2396987319893512. doi: 10.1177/2396987319893512.Epub 2019-12-06.

思春期の若者の睡眠に異なるトリプトファン/ラージニュートラルアミノ酸比を持つタンパク質の効果に関する無作為化二重盲検対照試験。PROTMORPHEUS研究

Randomized Double-Blind Controlled Trial on the Effect of Proteins with Different Tryptophan/Large Neutral Amino Acid Ratios on Sleep in Adolescents: The PROTMORPHEUS Study.
  • Oussama Saidi
  • Emmanuelle Rochette
  • Éric Doré
  • Freddy Maso
  • Julien Raoux
  • Fabien Andrieux
  • Maria Livia Fantini
  • Etienne Merlin
  • Bruno Pereira
  • Stéphane Walrand
  • Pascale Duché
  • Nutrients.2020 Jun;12(6). E1885. doi: 10.3390/nu12061885.Epub 2020-06-24.

手術後の上部消化管瘻の保存的治療における経腸栄養と非経口栄養の比較：多施設共同、無作為化、並行群、非盲検、第III相試験（NUTRILEAK試験）

Enteral versus parenteral nutrition in the conservative treatment of upper gastrointestinal fistula after surgery: a multicenter, randomized, parallel-group, open-label, phase III study (NUTRILEAK study).
  • Caroline Gronnier
  • Cécile Chambrier
  • Alain Duhamel
  • Benoît Dervaux
  • Denis Collet
  • Delphine Vaudoyer
  • Jean-Marc Régimbeau
  • Jacques Jougon
  • Jérémie Théréaux
  • Gil Lebreton
  • Julie Veziant
  • Alain Valverde
  • Pablo Ortega-Deballon
  • François Pattou
  • Muriel Mathonnet
  • Julie Perinel
  • Laura Beyer-Berjot
  • David Fuks
  • Philippe Rouanet
  • Jérémie H Lefevre
  • Pierre Cattan
  • Sophie Deguelte
  • Bernard Meunier
  • Jean-Jacques Tuech
  • Patrick Pessaux
  • Nicolas Carrere
  • Ephrem Salame
  • Eleonor Benaim
  • Bertrand Dousset
  • Simon Msika
  • Christophe Mariette
  • Guillaume Piessen
  • Trials.2020 Jun;21(1):448. 10.1186/s13063-020-04366-3. doi: 10.1186/s13063-020-04366-3.Epub 2020-06-02.

適応デザイン CONSORT Extension (ACE) ステートメント：適応デザインを用いた無作為化試験を報告するための説明と精緻化のためのガイドラインが記載されたチェックリスト

The Adaptive designs CONSORT Extension (ACE) statement: a checklist with explanation and elaboration guideline for reporting randomised trials that use an adaptive design.
  • Munyaradzi Dimairo
  • Philip Pallmann
  • James Wason
  • Susan Todd
  • Thomas Jaki
  • Steven A Julious
  • Adrian P Mander
  • Christopher J Weir
  • Franz Koenig
  • Marc K Walton
  • Jon P Nicholl
  • Elizabeth Coates
  • Katie Biggs
  • Toshimitsu Hamasaki
  • Michael A Proschan
  • John A Scott
  • Yuki Ando
  • Daniel Hind
  • Douglas G Altman
  • BMJ.2020 06;369:m115. doi: 10.1136/bmj.m115.Epub 2020-06-17.

質量分析に結合された生体適合性のある固相マイクロ抽出デバイスによる血漿サンプル中のエンドカンナビノイドの分析

Analysis of endocannabinoids in plasma samples by biocompatible solid-phase microextraction devices coupled to mass spectrometry.
  • Vinicius R Acquaro Junior
  • Germán Augusto Goméz-Ríos
  • Marcos Tascon
  • Maria Eugênia Costa Queiroz
  • Janusz Pawliszyn
  • Anal. Chim. Acta.2019 Dec;1091:135-145. S0003-2670(19)31045-1. doi: 10.1016/j.aca.2019.09.002.Epub 2019-09-05.

女性の先天性健康の改善：中央ペンシルバニア州女性健康調査におけるストロングヘルシーウーマン行動変容介入の長期的効果

Improving women's preconceptional health: long-term effects of the Strong Healthy Women behavior change intervention in the central Pennsylvania Women's Health Study.
  • Carol S Weisman
  • Marianne M Hillemeier
  • Danielle Symons Downs
  • Mark E Feinberg
  • Cynthia H Chuang
  • John J Botti
  • Anne-Marie Dyer
  • Womens Health Issues.2011 Jul-Aug;21(4):265-71. S1049-3867(11)00051-X. doi: 10.1016/j.whi.2011.03.007.Epub 2011-05-04.

パネス細胞アブレーションは、通常および高脂肪食後の急性壊死性膵炎のラットモデルにおける膵臓および腸の傷害を悪化させる

Paneth Cell Ablation Aggravates Pancreatic and Intestinal Injuries in a Rat Model of Acute Necrotizing Pancreatitis after Normal and High-Fat Diet.
  • Yuecheng Guo
  • Chunlan Huang
  • Liyan Liu
  • Xinyuan Fu
  • Yingying Lu
  • Junyuan Zheng
  • Qixiang Mei
  • Zehua Huang
  • Junjie Fan
  • Lungen Lu
  • Yue Zeng
  • Mediators Inflamm..2019;2019:8474523. doi: 10.1155/2019/8474523.Epub 2019-11-11.

暗闇下でのイネ中胚葉伸長を制御するためのカルリキンシグナル伝達の作用を明らかにした

Karrikin Signaling Acts Parallel to and Additively with Strigolactone Signaling to Regulate Rice Mesocotyl Elongation in Darkness.
  • Jianshu Zheng
  • Kai Hong
  • Longjun Zeng
  • Lei Wang
  • Shujing Kang
  • Minghao Qu
  • Jiarong Dai
  • Linyuan Zou
  • Lixin Zhu
  • Zhanpeng Tang
  • Xiangbing Meng
  • Bing Wang
  • Jiang Hu
  • Yonghui Zhao
  • Dali Zeng
  • Peng Cui
  • Quan Wang
  • Qian Qian
  • Yonghong Wang
  • Jiayang Li
  • Guosheng Xiong
  • Plant Cell.2020 Jul;tpc.00123.2020. doi: 10.1105/tpc.20.00123.Epub 2020-07-14.

非都市部の薬物注入者における日常的な薬物使用と危害軽減サービス利用の生態学的瞬間評価。同時並行混合方法による実現可能性調査

Ecological momentary assessment of daily drug use and harm reduction service utilization among people who inject drugs in non-urban areas: A concurrent mixed-method feasibility study.
  • Katie Biello
  • Peter Salhaney
  • Pablo K Valente
  • Ellen Childs
  • Jennifer Olson
  • Joel J Earlywine
  • Brandon Dl Marshall
  • Angela R Bazzi
  • Drug Alcohol Depend.2020 Jul;214:108167. S0376-8716(20)30332-X. doi: 10.1016/j.drugalcdep.2020.108167.Epub 2020-07-10.

ナノインク変性フレキシブルペーパー基板を用いた前立腺特異抗原へのビオチン化抗体の結合を利用したPSAモニタリングのための新規免疫センサー：バイオセンシング技術を用いた効率的な癌診断法の開発

A novel immunosensor for the monitoring of PSA using binding of biotinylated antibody to the prostate specific antigen based on nano-ink modified flexible paper substrate: efficient method for diagnosis of cancer using biosensing technology.
  • Fatemeh Farschi
  • Arezoo Saadati
  • Mohammad Hasanzadeh
  • Heliyon.2020 Jul;6(7):e04327. S2405-8440(20)31171-3. doi: 10.1016/j.heliyon.2020.e04327.Epub 2020-07-07.

体外受精のための卵巣刺激を受けたピーク血清プロゲステロン値上昇患者に対するGnRHアゴニストの中止とGnRHアンタゴニストの多剤併用：概念実証試験

Stop GnRH-Agonist Combined with Multiple-Dose GnRH-Antagonist for Patients with Elevated Peak Serum Progesterone Levels Undergoing Ovarian Stimulation for IVF: A Proof of Concept.
  • Raoul Orvieto
  • Michal Kirshenbaum
  • Valentina Galiano
  • Eran Zilberberg
  • Jigal Haas
  • Ravit Nahum
  • Gynecol. Obstet. Invest..2020 Jun;:1-5. 000508875. doi: 10.1159/000508875.Epub 2020-06-24.

ヒト B 細胞のクローン拡大と SARS-CoV-2 に対する抗体応答の収束

Human B cell clonal expansion and convergent antibody responses to SARS-CoV-2.
  • Sandra C A Nielsen
  • Fan Yang
  • Katherine J L Jackson
  • Ramona A Hoh
  • Katharina Röltgen
  • Bryan Stevens
  • Ji-Yeun Lee
  • Arjun Rustagi
  • Angela J Rogers
  • Abigail E Powell
  • Javaria Najeeb
  • Ana R Otrelo-Cardoso
  • Kathryn E Yost
  • Bence Daniel
  • Howard Y Chang
  • Ansuman T Satpathy
  • Theodore S Jardetzky
  • Peter S Kim
  • Taia T Wang
  • Benjamin A Pinsky
  • Catherine A Blish
  • Scott D Boyd
  • bioRxiv.2020 Jul;2020.07.08.194456. doi: 10.1101/2020.07.08.194456.Epub 2020-07-09.

応答面法を用いた超臨界流体システムによるレモンバーベナ葉からのフェニルプロパノイドとフラボノイドの最適化抽出

Optimized Extraction of Phenylpropanoids and Flavonoids from Lemon Verbena Leaves by Supercritical Fluid System Using Response Surface Methodology.
  • Francisco Javier Leyva-Jiménez
  • Jesús Lozano-Sánchez
  • Álvaro Fernández-Ochoa
  • María de la Luz Cádiz-Gurrea
  • David Arráez-Román
  • Antonio Segura-Carretero
  • Foods.2020 Jul;9(7). E931. doi: 10.3390/foods9070931.Epub 2020-07-14.

様々な商品におけるオキサチアピプロリンの既存の最大残留レベルの変更と輸入許容値の設定

Modification of the existing maximum residue levels and setting of import tolerances for oxathiapiprolin in various commodities.
  • Maria Anastassiadou
  • Alba Brancato
  • Luis Carrasco Cabrera
  • Luna Greco
  • Samira Jarrah
  • Aija Kazocina
  • Renata Leuschner
  • Jose Oriol Magrans
  • Ileana Miron
  • Stefanie Nave
  • Ragnor Pedersen
  • Marianna Raczyk
  • Hermine Reich
  • Silvia Ruocco
  • Angela Sacchi
  • Miguel Santos
  • Alois Stanek
  • Anne Theobald
  • Benedicte Vagenende
  • Alessia Verani
  • EFSA J.2019 Jul;17(7):e05759. EFS25759. doi: 10.2903/j.efsa.2019.5759.Epub 2019-07-25.

ビタミンA欠乏は、バルプロ酸誘発ラット自閉症モデルにおいて、自閉症様行動と腸神経系の異常を悪化させる

Vitamin A deficiency exacerbates autism-like behaviors and abnormalities of the enteric nervous system in a valproic acid-induced rat model of autism.
  • Boli Cheng
  • Jiang Zhu
  • Ting Yang
  • Si Wang
  • Huan Liu
  • Qionghui Wu
  • Xinhui Zhang
  • Jie Chen
  • Tingyu Li
  • Neurotoxicology.2020 Jul;79:184-190. S0161-813X(20)30091-7. doi: 10.1016/j.neuro.2020.06.004.Epub 2020-06-08.

巨大種子の起源について：ダブルココナッツ（Lodoicea maldivica）とその近縁種（Borasseae, Arecaceae）のマクロ進化

On the origin of giant seeds: the macroevolution of the double coconut (Lodoicea maldivica) and its relatives (Borasseae, Arecaceae).
  • Sidonie Bellot
  • Ross P Bayton
  • Thomas L P Couvreur
  • Steven Dodsworth
  • Wolf L Eiserhardt
  • Maïté S Guignard
  • Hugh W Pritchard
  • Lucy Roberts
  • Peter E Toorop
  • William J Baker
  • New Phytol..2020 Jun;doi: 10.1111/nph.16750.Epub 2020-06-16.

ヒストンメチル化酵素KMT2Dをコードする遺伝子の機能喪失は、ミトコンドリア呼吸の調節障害につながる

Loss of Function of the Gene Encoding the Histone Methyltransferase KMT2D Leads to Deregulation of Mitochondrial Respiration.
  • Consiglia Pacelli
  • Iolanda Adipietro
  • Natascia Malerba
  • Gabriella Maria Squeo
  • Claudia Piccoli
  • Angela Amoresano
  • Gabriella Pinto
  • Pietro Pucci
  • Ji-Eun Lee
  • Kai Ge
  • Nazzareno Capitanio
  • Giuseppe Merla
  • Cells.2020 Jul;9(7). E1685. doi: 10.3390/cells9071685.Epub 2020-07-13.

調節性T細胞は、特発性早産/出産のサブセットと有害な新生児のアウトカムで役割を果たしています

Regulatory T Cells Play a Role in a Subset of Idiopathic Preterm Labor/Birth and Adverse Neonatal Outcomes.
  • Nardhy Gomez-Lopez
  • Marcia Arenas-Hernandez
  • Roberto Romero
  • Derek Miller
  • Valeria Garcia-Flores
  • Yaozhu Leng
  • Yi Xu
  • Jose Galaz
  • Sonia S Hassan
  • Chaur-Dong Hsu
  • Harley Tse
  • Carmen Sanchez-Torres
  • Bogdan Done
  • Adi L Tarca
  • Cell Rep.2020 Jul;32(1):107874. S2211-1247(20)30855-X. doi: 10.1016/j.celrep.2020.107874.

チリ北部の海水淡水化プラントからの逆浸透膜(ROM)からのバイオファウリングの特性評価と除去を、sp. Ni1-LEM上清を用いて行った

Characterization and removal of biofouling from reverse osmosis membranes (ROMs) from a desalination plant in Northern Chile, using sp. Ni1-LEM supernatant.
  • Hernán Vera-Villalobos
  • Vilma Pérez
  • Francisco Contreras
  • Valezka Alcayaga
  • Vladimir Avalos
  • Carlos Riquelme
  • Fernando Silva-Aciares
  • Biofouling.2020 Jun;:1-11. doi: 10.1080/08927014.2020.1776268.Epub 2020-06-16.

中性子回折、FマジックアングルスピニングNMR、密度汎関数理論計算を組み合わせたThFの結晶構造の解明

Insight into the Crystalline Structure of ThF with the Combined Use of Neutron Diffraction, F Magic-Angle Spinning-NMR, and Density Functional Theory Calculations.
  • Laura Martel
  • Elisa Capelli
  • Monique Body
  • Marco Klipfel
  • Ondrej Beneš
  • Louis Maksoud
  • Phillipe E Raison
  • Emmanuelle Suard
  • Lucas Visscher
  • Catherine Bessada
  • Christophe Legein
  • Thibault Charpentier
  • Attila Kovács
  • Inorg Chem.2018 Dec;57(24):15350-15360. doi: 10.1021/acs.inorgchem.8b02683.Epub 2018-11-26.

ハイリスク妊婦の早産予防のための膣と筋肉内プロゲストーゲンの比較（VICTORIA試験）：多施設共同、オープンラベル無作為化試験およびメタアナリシス

Vaginal compared with intramuscular progestogen for preventing preterm birth in high-risk pregnant women (VICTORIA study): a multicentre, open-label randomised trial and meta-analysis.
  • S-J Choi
  • D W Kwak
  • K Kil
  • S-C Kim
  • J-Y Kwon
  • Y H Kim
  • S Na
  • J-G Bae
  • H-H Cha
  • J-Y Shim
  • K Y Oh
  • K A Lee
  • S M Kim
  • I A Cho
  • S M Lee
  • G J Cho
  • Y S Jo
  • G Y Choi
  • S K Choi
  • S E Hur
  • H S Hwang
  • Y J Kim
  • BJOG.2020 Jun;doi: 10.1111/1471-0528.16365.Epub 2020-06-14.

ジストログリカンの喪失は、欠損したミトーシス媒介のゲノム不安定性を介して細胞の老化を促進する

Loss of Dystroglycan Drives Cellular Senescence via Defective Mitosis-Mediated Genomic Instability.
  • Guadalupe Elizabeth Jimenez-Gutierrez
  • Ricardo Mondragon-Gonzalez
  • Luz Adriana Soto-Ponce
  • Wendy Lilián Gómez-Monsiváis
  • Ian García-Aguirre
  • Ruth Abigail Pacheco-Rivera
  • Rocío Suárez-Sánchez
  • Andrea Brancaccio
  • Jonathan Javier Magaña
  • Rita C R Perlingeiro
  • Bulmaro Cisneros
  • Int J Mol Sci.2020 Jul;21(14). E4961. doi: 10.3390/ijms21144961.Epub 2020-07-14.

β-カテニンは、eNOS活性と流れに依存した抗アポトーシス遺伝子の発現を制御することで、内皮細胞の生存を促進する

β-catenin promotes endothelial survival by regulating eNOS activity and flow-dependent anti-apoptotic gene expression.
  • Virginia Tajadura
  • Marie Haugsten Hansen
  • Joy Smith
  • Hannah Charles
  • Matthew Rickman
  • Keith Farrell-Dillon
  • Vasco Claro
  • Christina Warboys
  • Albert Ferro
  • Cell Death Dis.2020 Jun;11(6):493. 10.1038/s41419-020-2687-6. doi: 10.1038/s41419-020-2687-6.Epub 2020-06-30.

HSP90インヒビターが循環停止後のドネーションのポルシンモデルにおける肺保護を改善する

HSP90 Inhibitor Improves Lung Protection in Porcine Model of Donation after Circulatory Arrest.
  • Basil S Nasir
  • Caroline Landry
  • Ahmed Menaouar
  • Jean-François Germain
  • Shant Der Sarkissian
  • Louis-Mathieu Stevens
  • Henry Aceros
  • Jean-François Cailhier
  • Charles Leduc
  • Moishe Liberman
  • Nicolas Noiseux
  • Pasquale Ferraro
  • Ann. Thorac. Surg..2020 Jul;S0003-4975(20)31111-5. doi: 10.1016/j.athoracsur.2020.05.079.Epub 2020-07-08.

ビタミンB12の状態のバイオマーカーに対するホエイプロテインサプリメントとレジスタンストレーニングの効果。健康な高齢者における 1 年間の無作為化介入（CALM 試験）

Effects of Prolonged Whey Protein Supplementation and Resistance Training on Biomarkers of Vitamin B12 Status: A 1-Year Randomized Intervention in Healthy Older Adults (the CALM Study).
  • Eva Greibe
  • Søren Reitelseder
  • Rasmus L Bechshøft
  • Jacob Bülow
  • Grith W Højfeldt
  • Simon R Schacht
  • Mads L Knudsen
  • Inge Tetens
  • Marie S Ostenfeld
  • Ulla R Mikkelsen
  • Christian W Heegaard
  • Ebba Nexo
  • Lars Holm
  • Nutrients.2020 Jul;12(7). E2015. doi: 10.3390/nu12072015.Epub 2020-07-07.

生物学的時代の潰瘍性大腸炎患者における大腸摘出術後の罹患率と死亡率の傾向（2002-2013年）。全国の入院患者サンプルを用いた研究

Trends in Morbidity and Mortality Following Colectomy Among Patients with Ulcerative Colitis in the Biologic Era (2002-2013): A Study Using the National Inpatient Sample.
  • Babatunde Olaiya
  • Benjamin D Renelus
  • Mikolaj Filon
  • Sumona Saha
  • Dig. Dis. Sci..2020 Jul;10.1007/s10620-020-06474-1. doi: 10.1007/s10620-020-06474-1.Epub 2020-07-16.

2004年から2014年までのCoRISコホートにおけるHIV感染者の男女間の疫学および死亡率の違い

Differences in epidemiology and mortality between men and women with HIV infection in the CoRIS cohort from 2004 to 2014.
  • Constanza Muñoz Hornero
  • Alfonso Muriel
  • Marta Montero
  • José Antonio Iribarren
  • Mar Masía
  • Leopoldo Muñoz
  • Gloria Sampériz
  • Gemma Navarro
  • Santiago Moreno
  • María Jesús Pérez-Elías
  • Enferm. Infecc. Microbiol. Clin..2020 Jul;S0213-005X(20)30220-2. doi: 10.1016/j.eimc.2020.05.021.Epub 2020-07-14.

lncRNA ZEB1-AS1は、糖尿病性腎症におけるmiR-216a-5p/BMP7軸を制御することにより、高グルコース誘導性EMTと線維芽細胞増殖を抑制することを明らかにした

lncRNA ZEB1-AS1 inhibits high glucose-induced EMT and fibrogenesis by regulating the miR-216a-5p/BMP7 axis in diabetic nephropathy.
  • Qingqing Meng
  • Xiaolin Zhai
  • Yi Yuan
  • Qing Ji
  • Pengyuan Zhang
  • Braz. J. Med. Biol. Res..2020;53(4):e9288. S0100-879X2020000400607. doi: 10.1590/1414-431X20209288.Epub 2020-04-09.

健康なボランティアおよびHIV-1感染者におけるマラビロクの薬物動態および/または有効性にCYP3A5遺伝子多型が及ぼす臨床的影響はなかった

No Clinical Impact of CYP3A5 Gene Polymorphisms on the Pharmacokinetics and/or Efficacy of Maraviroc in Healthy Volunteers and HIV-1-Infected Subjects.
  • Manoli Vourvahis
  • Lynn McFadyen
  • Sunil Nepal
  • Srinivas Rao Valluri
  • Annie Fang
  • Gwendolyn D Fate
  • Linda S Wood
  • Jean-Claude Marshall
  • Phylinda L S Chan
  • Angus Nedderman
  • Julian Haynes
  • Mark E Savage
  • Andrew Clark
  • Kimberly Y Smith
  • Jayvant Heera
  • J Clin Pharmacol.2019 01;59(1):139-152. doi: 10.1002/jcph.1306.Epub 2018-09-07.

グルココルチコイド治療を受けている患者の骨密度に対するカルシウムおよびビタミンD化合物の効果：ネットワークメタアナリシス

The effect of calcium and vitamin D compounds on bone mineral density in patients undergoing glucocorticoid therapies: a network meta-analysis.
  • Jiawen Deng
  • Zachary Silver
  • Emma Huang
  • Elena Zheng
  • Kyra Kavanagh
  • Jannusha Panicker
  • Clin. Rheumatol..2020 Jul;10.1007/s10067-020-05294-y. doi: 10.1007/s10067-020-05294-y.Epub 2020-07-17.

COVID-19の肝機能への影響：北イタリアの内科ユニットからの結果

Impact of COVID-19 on liver function: results from an internal medicine unit in Northern Italy.
  • Marco Vincenzo Lenti
  • Federica Borrelli de Andreis
  • Ivan Pellegrino
  • Catherine Klersy
  • Stefania Merli
  • Emanuela Miceli
  • Nicola Aronico
  • Caterina Mengoli
  • Michele Di Stefano
  • Sara Cococcia
  • Giovanni Santacroce
  • Simone Soriano
  • Federica Melazzini
  • Mariangela Delliponti
  • Fausto Baldanti
  • Antonio Triarico
  • Gino Roberto Corazza
  • Massimo Pinzani
  • Antonio Di Sabatino
  • Intern Emerg Med.2020 Jul;10.1007/s11739-020-02425-w. doi: 10.1007/s11739-020-02425-w.Epub 2020-07-10.

限局性前立腺癌に対する高線量率ブラキセラピーは、腫瘍を冷たい状態から熱い状態に変える

High dose-rate brachytherapy of localized prostate cancer converts tumors from cold to hot.
  • Simon P Keam
  • Heloise Halse
  • Thu Nguyen
  • Minyu Wang
  • Nicolas Van Kooten Losio
  • Catherine Mitchell
  • Franco Caramia
  • David J Byrne
  • Sue Haupt
  • Georgina Ryland
  • Phillip K Darcy
  • Shahneen Sandhu
  • Piers Blombery
  • Ygal Haupt
  • Scott G Williams
  • Paul J Neeson
  • J Immunother Cancer.2020 Jun;8(1). e000792. doi: 10.1136/jitc-2020-000792.

未治療のB型慢性肝炎患者における自然免疫応答および適応免疫応答のサイトカインプロファイルと臨床的・生物学的特徴との関連

Association among cytokine profiles of innate and adaptive immune responses and clinical-virological features in untreated patients with chronic hepatitis B.
  • Yurong Gu
  • Yifan Lian
  • Qiaolan Zheng
  • Zexuan Huang
  • Lin Gu
  • Yanhua Bi
  • Jing Li
  • Yanlin Huang
  • Yuankai Wu
  • Lubiao Chen
  • Yuehua Huang
  • BMC Infect. Dis..2020 Jul;20(1):509. 10.1186/s12879-020-05233-x. doi: 10.1186/s12879-020-05233-x.Epub 2020-07-14.

硫黄マスタードに暴露されたイランの退役軍人における酸化ストレスの増加と関連したテロメア短縮

Telomere shortening associated with increased levels of oxidative stress in sulfur mustard-exposed Iranian veterans.
  • Effat Behravan
  • Seyed Adel Moallem
  • Fatemeh Kalalinia
  • Mahnaz Ahmadimanesh
  • Peter Blain
  • Paul Jowsey
  • Shahriar Khateri
  • Mohammad Mahdi Forghanifard
  • Mahdi BalaliMood
  • Mutat Res Genet Toxicol Environ Mutagen.2018 Oct;834:1-5. S1383-5718(17)30355-8. doi: 10.1016/j.mrgentox.2018.06.017.Epub 2018-06-20.

GETECCUによるENEIDA登録（炎症性腸疾患の遺伝的・環境的決定要因に関する全国的研究）：デザイン、モニタリング、機能

The ENEIDA registry (Nationwide study on genetic and environmental determinants of inflammatory bowel disease) by GETECCU: Design, monitoring and functions.
  • Yamile Zabana
  • Julián Panés
  • Pilar Nos
  • Fernando Gomollón
  • Maria Esteve
  • Valle García-Sánchez
  • Javier P Gisbert
  • Manuel Barreiro-de-Acosta
  • Eugeni Domènech
  • Gastroenterol Hepatol.2020 Jul;S0210-5705(20)30165-5. doi: 10.1016/j.gastrohep.2020.05.007.Epub 2020-07-13.

DNAメチル化に基づくテロメア長の推定法

DNA methylation-based estimator of telomere length.
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  • Pei-Chien Tsai
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  • Charles Kooperberg
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  • Yun Li
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  • Ian J Deary
  • James D Stewart
  • Eric A Whitsel
  • Themistocles L Assimes
  • Wei Chen
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Min Gong et al: (Risk for Infections During Treatment with Denosumab for Osteoporosis: a Systematic Review and Metaanalysis)からの編集者への手紙への回答

Response to Letter to the Editor from Min Gong et al: (Risk for Infections During Treatment with Denosumab for Osteoporosis: a Systematic Review and Meta-analysis).
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  • Dana Rosenberg
  • Tomer Avni
  • Daniel Shepshelovich
  • Gloria Tsvetov
  • Anat Gafter-Gvili
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ヒト膵臓癌における細胞浸潤・遊走を制御する細胞外小胞輸送を介した長鎖ノンコーディングRNA HULCとMicroRNA-622の相互作用

The Interaction Between Long Non-coding RNA HULC and MicroRNA-622 via Transfer by Extracellular Vesicles Regulates Cell Invasion and Migration in Human Pancreatic Cancer.
  • Kenji Takahashi
  • Kazuya Koyama
  • Yu Ota
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  • Keisuke Yamakita
  • Satoshi Fujii
  • Yohei Kitano
  • Front Oncol.2020;10:1013. doi: 10.3389/fonc.2020.01013.Epub 2020-06-23.

腸骨大腿部深部静脈血栓症の治療におけるAngioJet Pharmacomechanical Thrombectomyおよびカテーテル指示型血栓溶解療法とカテーテル指示型血栓溶解療法のみの比較。単一施設のレトロスペクティブコホート研究

AngioJet Pharmacomechanical Thrombectomy and Catheter Directed Thrombolysis vs. Catheter Directed Thrombolysis Alone for the Treatment of Iliofemoral Deep Vein Thrombosis: A Single Centre Retrospective Cohort Study.
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  • Oscar W Johnson
  • Justinas Silickas
  • Prakash Saha
  • Narayan Thulasidasan
  • Narayan Karunanithy
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  • Eur J Vasc Endovasc Surg.2020 Jul;S1078-5884(20)30423-8. doi: 10.1016/j.ejvs.2020.05.006.Epub 2020-07-11.

1.5Tおよび3TでのMRI時の両側DBSインプラント近傍組織のRF誘導加熱：外科的リード管理の役割

RF-induced heating in tissue near bilateral DBS implants during MRI at 1.5 T and 3T: The role of surgical lead management.
  • Laleh Golestanirad
  • John Kirsch
  • Giorgio Bonmassar
  • Sean Downs
  • Behzad Elahi
  • Alastair Martin
  • Maria-Ida Iacono
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  • Lawrence L Wald
  • Julie Pilitsis
  • Neuroimage.2019 01;184:566-576. S1053-8119(18)30819-X. doi: 10.1016/j.neuroimage.2018.09.034.Epub 2018-09-19.

黄斑変性症に対するHLAマッチ同種iPS細胞由来RPE移植

HLA-Matched Allogeneic iPS Cells-Derived RPE Transplantation for Macular Degeneration.
  • Sunao Sugita
  • Michiko Mandai
  • Yasuhiko Hirami
  • Seiji Takagi
  • Tadao Maeda
  • Masashi Fujihara
  • Mitsuhiro Matsuzaki
  • Midori Yamamoto
  • Kyoko Iseki
  • Naoko Hayashi
  • Ayumi Hono
  • Shoko Fujino
  • Naoshi Koide
  • Noriko Sakai
  • Yumiko Shibata
  • Motoki Terada
  • Mitsuhiro Nishida
  • Hiromi Dohi
  • Masaki Nomura
  • Naoki Amano
  • Hirokazu Sakaguchi
  • Chikako Hara
  • Kazuichi Maruyama
  • Takashi Daimon
  • Masataka Igeta
  • Toshihiko Oda
  • Utako Shirono
  • Misato Tozaki
  • Kota Totani
  • Satoshi Sugiyama
  • Kohji Nishida
  • Yasuo Kurimoto
  • Masayo Takahashi
  • J Clin Med.2020 Jul;9(7). E2217. doi: 10.3390/jcm9072217.Epub 2020-07-13.

中等度および重度の過活動膀胱に対する電気鍼治療とソリフェナシンの効果：多施設、無作為化比較試験プロトコール

Effect of electroacupuncture versus solifenacin for moderate and severe overactive bladder: a multi-centre, randomized controlled trial study protocol.
  • Qian Wen
  • Ning Li
  • Xueling Wang
  • Hao Li
  • Fengwei Tian
  • Weiwei Chen
  • Yanyan Lu
  • Zhishun Liu
  • BMC Complement Med Ther.2020 Jul;20(1):224. 10.1186/s12906-020-03018-y. doi: 10.1186/s12906-020-03018-y.Epub 2020-07-16.

神経細胞の塩化物押し出しを強化することで、神経障害性疼痛におけるα2/α3 GABAを介した鎮痛効果を回復させる

Enhancing neuronal chloride extrusion rescues α2/α3 GABA-mediated analgesia in neuropathic pain.
  • Louis-Etienne Lorenzo
  • Antoine G Godin
  • Francesco Ferrini
  • Karine Bachand
  • Isabel Plasencia-Fernandez
  • Simon Labrecque
  • Alexandre A Girard
  • Dominic Boudreau
  • Irenej Kianicka
  • Martin Gagnon
  • Nicolas Doyon
  • Alfredo Ribeiro-da-Silva
  • Yves De Koninck
  • Nat Commun.2020 02;11(1):869. 10.1038/s41467-019-14154-6. doi: 10.1038/s41467-019-14154-6.Epub 2020-02-13.

大動脈平滑筋における電圧依存性KチャネルとSERCAポンプの活性化を介したゲミグリプチンの血管拡張作用

The vasodilatory effect of gemigliptin via activation of voltage-dependent K channels and SERCA pumps in aortic smooth muscle.
  • Hee Seok Jung
  • Mi Seon Seo
  • Jin Ryeol An
  • Minji Kang
  • Ryeon Heo
  • Hongliang Li
  • Won-Kyo Jung
  • Il-Whan Choi
  • Eun-Hee Cho
  • Hongzoo Park
  • Young Min Bae
  • Won Sun Park
  • Eur. J. Pharmacol..2020 Jun;882:173243. S0014-2999(20)30335-6. doi: 10.1016/j.ejphar.2020.173243.Epub 2020-06-12.

雌ニホンウズラの肝臓に及ぼす鉛の慢性曝露の影響：病理組織学的損傷、酸化ストレス、AMP活性化プロテインキナーゼに基づく脂質代謝障害

The effects of chronic lead exposure on the liver of female Japanese quail (Coturnix japonica): Histopathological damages, oxidative stress and AMP-activated protein kinase based lipid metabolism disorder.
  • Honghong Kou
  • Jing Ya
  • Xuebin Gao
  • Hongfeng Zhao
  • Ecotoxicol. Environ. Saf..2020 Mar;190:110055. S0147-6513(19)31386-7. doi: 10.1016/j.ecoenv.2019.110055.Epub 2019-12-12.

KLHL24の不活性化に伴う致死性不整脈を伴う心筋症

Cardiomyopathy with lethal arrhythmias associated with inactivation of KLHL24.
  • Carola Hedberg-Oldfors
  • Alexandra Abramsson
  • Daniel P S Osborn
  • Olof Danielsson
  • Afsoon Fazlinezhad
  • Yalda Nilipour
  • Laila Hübbert
  • Inger Nennesmo
  • Kittichate Visuttijai
  • Jaipreet Bharj
  • Evmorfia Petropoulou
  • Azza Shoreim
  • Barbara Vona
  • Najmeh Ahangari
  • Marcela Dávila López
  • Mohammad Doosti
  • Rakesh Kumar Banote
  • Reza Maroofian
  • Malin Edling
  • Mehdi Taherpour
  • Henrik Zetterberg
  • Ehsan Ghayoor Karimiani
  • Anders Oldfors
  • Yalda Jamshidi
  • Hum. Mol. Genet..2019 06;28(11):1919-1929. 5305756. doi: 10.1093/hmg/ddz032.

中等度から重度の肺疾患を有する嚢胞性線維症患者の気道マイクロバイオームのアンターゲットメタゲノム調査

Untargeted Metagenomic Investigation of the Airway Microbiome of Cystic Fibrosis Patients with Moderate-Severe Lung Disease.
  • Giovanni Bacci
  • Giovanni Taccetti
  • Daniela Dolce
  • Federica Armanini
  • Nicola Segata
  • Francesca Di Cesare
  • Vincenzina Lucidi
  • Ersilia Fiscarelli
  • Patrizia Morelli
  • Rosaria Casciaro
  • Anna Negroni
  • Alessio Mengoni
  • Annamaria Bevivino
  • Microorganisms.2020 Jul;8(7). E1003. doi: 10.3390/microorganisms8071003.Epub 2020-07-04.

使い捨てピペット抽出法と超高速液体クロマトグラフィー・タンデム質量分析法による脳脊髄液試料中のアナンダミドの定量

Determination of anandamide in cerebrospinal fluid samples by disposable pipette extraction and ultra-high performance liquid chromatography tandem mass spectrometry.
  • Igor Gustavo de Carvalho Oliveira
  • Camila Marchioni
  • Maria Eugênia Costa Queiroz
  • J. Chromatogr. B Analyt. Technol. Biomed. Life Sci..2019 Nov;1130-1131:121809. S1570-0232(19)30687-7. doi: 10.1016/j.jchromb.2019.121809.Epub 2019-10-04.

ウィスターラットの実験的に誘発された微小結晶性関節炎における滑膜炎症過程のレーザー治療

Laser treatment of synovial inflammatory process in experimentally induced microcrystalline arthritis in Wistar rats.
  • Débora Mara Fortes Bartoli
  • Airton Luiz Felizatti
  • Fernando Russo Costa do Bomfim
  • Julia Leme Bovo
  • Andrea Aparecida de Aro
  • Maria Esméria Corezzola do Amaral
  • Marcelo Augusto Marretto Esquisatto
  • Lasers Med Sci.2020 Jun;10.1007/s10103-020-03055-6. doi: 10.1007/s10103-020-03055-6.Epub 2020-06-10.

術前の血糖値とヘモグロビンa1c値は、ペニス埋入術を受ける糖尿病男性における術後感染症の予測にはならない

Immediate preoperative blood glucose and hemoglobin a1c levels are not predictive of postoperative infections in diabetic men undergoing penile prosthesis placement.
  • Mohamad M Osman
  • Linda M Huynh
  • Farouk M El-Khatib
  • Maxwell Towe
  • Huang-Wei Su
  • Robert Andrianne
  • Gregory Barton
  • Gregory Broderick
  • Arthur L Burnett
  • Jeffrey D Campbell
  • Jonathan Clavell-Hernandez
  • Jessica Connor
  • Martin Gross
  • Ross Guillum
  • Amy I Guise
  • Georgios Hatzichristodoulou
  • Gerard D Henry
  • Tung-Chin Hsieh
  • Lawrence C Jenkins
  • Christopher Koprowski
  • Kook B Lee
  • Aaron Lentz
  • Ricardo M Munarriz
  • Daniar Osmonov
  • Shu Pan
  • Kevin Parikh
  • Sung Hun Park
  • Amir S Patel
  • Paul Perito
  • Hossein Sadeghi-Nejad
  • Maxime Sempels
  • Jay Simhan
  • Run Wang
  • Faysal A Yafi
  • Int. J. Impot. Res..2020 Mar;10.1038/s41443-020-0261-5. doi: 10.1038/s41443-020-0261-5.Epub 2020-03-20.

カメルーン産の食用・薬用キノコPleurotus tuber-regium（Agaricomycetes）の粗抽出物の抗真菌・抗菌活性の比較評価

Comparative Assessment of Antifungal and Antibacterial Activities of Crude Extracts of the King Tuber Culinary-Medicinal Mushroom, Pleurotus tuber-regium (Agaricomycetes) from Cameroon.
  • Blondo-Pascal Metsebing
  • Romuald Oba
  • Dominique Claude Mossebo
  • Thierry Youmbi Fonkui
  • Fabrice Tsigaing Tsigain
  • Marthe Carine Djuidje Fotsing
  • Tata Charlotte Mungoh
  • Derek Ntantoh Ndinteh
  • Int J Med Mushrooms.2020;22(4):359-366. 742ee6254aa2c7db,25f63c9a2c43158e. doi: 10.1615/IntJMedMushrooms.2020034178.

シグナル伝達型アダプター蛋白質-2は、造血ストレス時のB系統リンパ球の回復を遅延させる

Signal-transducing adaptor protein-2 delays recovery of B lineage lymphocytes during hematopoietic stress.
  • Michiko Ichii
  • Kenji Oritani
  • Jun Toda
  • Hideaki Saito
  • Henyun Shi
  • Hirohiko Shibayama
  • Daisuke Motooka
  • Yuichi Kitai
  • Ryuta Muromoto
  • Jun-Ichi Kashiwakura
  • Kodai Saitoh
  • Daisuke Okuzaki
  • Tadashi Matsuda
  • Yuzuru Kanakura
  • Haematologica.2020 Jan;haematol.2019.225573. doi: 10.3324/haematol.2019.225573.Epub 2020-01-23.

COVID-19入院患者の肺高血圧と右室病変

Pulmonary hypertension and right ventricular involvement in hospitalised patients with COVID-19.
  • Matteo Pagnesi
  • Luca Baldetti
  • Alessandro Beneduce
  • Francesco Calvo
  • Mario Gramegna
  • Vittorio Pazzanese
  • Giacomo Ingallina
  • Antonio Napolano
  • Renato Finazzi
  • Annalisa Ruggeri
  • Silvia Ajello
  • Giulio Melisurgo
  • Paolo Guido Camici
  • Paolo Scarpellini
  • Moreno Tresoldi
  • Giovanni Landoni
  • Fabio Ciceri
  • Anna Mara Scandroglio
  • Eustachio Agricola
  • Alberto Maria Cappelletti
  • Heart.2020 Jul;heartjnl-2020-317355. doi: 10.1136/heartjnl-2020-317355.Epub 2020-07-16.

サウジアラビア王国の女子大生の体重と摂食態度の研究。異なる体重評価方法間の比較

Study of bodyweight and eating attitude among female university members in the Kingdom of Saudi Arabia: A comparison between different methods of weight assessment.
  • Rania Naguib
  • Marwa M R Tawfik
  • Sukainah A Alsubaiei
  • Altaf M Almoallem
  • Dana M Alajlouni
  • Tahani A Alruwaili
  • Wd S Sendy
  • Zainab Al Habib
  • J Family Med Prim Care.2020 Apr;9(4):2071-2078. JFMPC-9-2071. doi: 10.4103/jfmpc.jfmpc_1058_19.Epub 2020-04-30.

光学的に純粋なL-乳酸およびD-乳酸の新規生産者としての代謝工学的に設計されたLactobacillus gasseri JCM 1131

Metabolically engineered Lactobacillus gasseri JCM 1131 as a novel producer of optically pure L- and D-lactate.
  • Bojan Žunar
  • Antonija Trontel
  • Marina Svetec Miklenić
  • Juliana Lana Prah
  • Anamarija Štafa
  • Nenad Marđetko
  • Mario Novak
  • Božidar Šantek
  • Ivan Krešimir Svetec
  • World J. Microbiol. Biotechnol..2020 Jul;36(8):111. 10.1007/s11274-020-02887-2. doi: 10.1007/s11274-020-02887-2.Epub 2020-07-13.

マラソンに向かう途中で-子どもと若者のマスランニングイベント参加へのモチベーション．ポズナンハーフマラソンパイロット調査の結果

On the Way to the Marathon-Motivation for Participating in Mass Running Events Among Children and Adolescents: Results of the Poznan Half Marathon Pilot Study.
  • Ewa Malchrowicz-Mośko
  • Arkaitz Castañeda-Babarro
  • Patxi León Guereño
  • Int J Environ Res Public Health.2020 Jul;17(14). E5098. doi: 10.3390/ijerph17145098.Epub 2020-07-15.

嫌気性細菌に対する抗菌作用を有するハイドロキシアパタイトをベースとしたバイオナノコンポジットの調製と予備評価

Preparation and preliminary evaluation of bio-nanocomposites based on hydroxyapatites with antibacterial properties against anaerobic bacteria.
  • Katarzyna Zawisza
  • Paulina Sobierajska
  • Nicole Nowak
  • Anna Kedziora
  • Kamila Korzekwa
  • Blazej Pozniak
  • Marta Tikhomirov
  • Julia Miller
  • Lucyna Mrowczynska
  • Rafal J Wiglusz
  • Mater Sci Eng C Mater Biol Appl.2020 Jan;106:110295. S0928-4931(18)32616-X. doi: 10.1016/j.msec.2019.110295.Epub 2019-10-10.

血液学的悪性腫瘍患者，高用量化学療法および自己造血幹細胞移植（自己造血幹細胞移植）を受けた患者における補体活性化コレクトインおよび関連セリンプロテアーゼの役割について

The Role of Complement Activating Collectins and Associated Serine Proteases in Patients With Hematological Malignancies, Receiving High-Dose Chemotherapy, and Autologous Hematopoietic Stem Cell Transplantations (Auto-HSCT).
  • Anna S Świerzko
  • Mateusz Michalski
  • Anna Sokołowska
  • Mateusz Nowicki
  • Łukasz Eppa
  • Agnieszka Szala-Poździej
  • Iwona Mitrus
  • Anna Szmigielska-Kapłon
  • Małgorzata Sobczyk-Kruszelnicka
  • Katarzyna Michalak
  • Aleksandra Gołos
  • Agnieszka Wierzbowska
  • Sebastian Giebel
  • Krzysztof Jamroziak
  • Marek L Kowalski
  • Olga Brzezińska
  • Steffen Thiel
  • Jens C Jensenius
  • Katarzyna Kasperkiewicz
  • Maciej Cedzyński
  • Front Immunol.2018;9:2153. doi: 10.3389/fimmu.2018.02153.Epub 2018-09-20.

診断から2回目の治療までの時間は、進行期の濾胞性リンパ腫患者における全生存期間の有望な代替指標である

Time from diagnosis to 2nd treatment is a promising surrogate for overall survival in patients with advanced stage follicular lymphoma.
  • Jacob D Soumerai
  • Andy Ni
  • Anna Alperovich
  • Connie Batlevi
  • Kurt S Bantilan
  • Thais Fischer
  • Amanda R Copeland
  • Katy Smith
  • Zhitao Ying
  • Anas Younes
  • Andrew D Zelenetz
  • Leuk. Lymphoma.2020 Jul;:1-8. doi: 10.1080/10428194.2020.1791850.Epub 2020-07-15.

上腕二頭筋遠位部断裂に対する縫合糸アンカー再挿入術：断裂した腱の組織学的解析と短期・長期フォローアップにおける臨床結果

Suture anchor reinsertions of distal biceps rupture: a histological analysis of torn tendon and clinical results at short- and long-term follow up.
  • Pierfrancesco Luciani
  • Luca Farinelli
  • Elisa Senigagliesi
  • Nicola Setaro
  • Sandra Manzotti
  • Antonio Gigante
  • J Shoulder Elbow Surg.2020 Jul;S1058-2746(20)30543-7. doi: 10.1016/j.jse.2020.06.025.Epub 2020-07-07.

フィブリノゲンベンゾチアゾールの薬物相互作用の基礎的なメカニズムを計算と実験的アプローチを用いてマッピングする

Mapping the underlying mechanisms of fibrinogen benzothiazole drug interactions using computational and experimental approaches.
  • Michael González-Durruthy
  • Gustavo Scanavachi
  • Ramón Rial
  • Zhen Liu
  • M Natália D S Cordeiro
  • Rosangela Itri
  • Juan M Ruso
  • Int. J. Biol. Macromol..2020 Jul;163:730-744. S0141-8130(20)33790-9. doi: 10.1016/j.ijbiomac.2020.07.044.Epub 2020-07-09.

Baicaleinは、内皮一酸化窒素合成酵素の機能障害を改善し、酸化ストレスと線維化を抑制することで、ストレプトゾトシン誘発性I型糖尿病に伴う勃起障害を緩和する

Baicalein Alleviates Erectile Dysfunction Associated With Streptozotocin-Induced Type I Diabetes by Ameliorating Endothelial Nitric Oxide Synthase Dysfunction, Inhibiting Oxidative Stress and Fibrosis.
  • Yinwei Chen
  • Bingyan Zhou
  • Zhe Yu
  • Penghui Yuan
  • Taotao Sun
  • Jianan Gong
  • Yan Zhang
  • Tao Wang
  • Shaogang Wang
  • Kang Liu
  • JiHong Liu
  • J Sex Med.2020 Jun;S1743-6095(20)30607-X. doi: 10.1016/j.jsxm.2020.04.390.Epub 2020-06-22.

小児肥大型心筋症における突然死のリスク予測モデルの開発（HCMリスクキッズ）

Development of a Novel Risk Prediction Model for Sudden Cardiac Death in Childhood Hypertrophic Cardiomyopathy (HCM Risk-Kids).
  • Gabrielle Norrish
  • Tao Ding
  • Ella Field
  • Lidia Ziólkowska
  • Iacopo Olivotto
  • Giuseppe Limongelli
  • Aristides Anastasakis
  • Robert Weintraub
  • Elena Biagini
  • Luca Ragni
  • Terence Prendiville
  • Sophie Duignan
  • Karen McLeod
  • Maria Ilina
  • Adrián Fernández
  • Regina Bökenkamp
  • Anwar Baban
  • Peter Kubuš
  • Piers E F Daubeney
  • Georgia Sarquella-Brugada
  • Sergi Cesar
  • Chiara Marrone
  • Vinay Bhole
  • Constancio Medrano
  • Orhan Uzun
  • Elspeth Brown
  • Ferran Gran
  • Francisco J Castro
  • Graham Stuart
  • Gabriele Vignati
  • Roberto Barriales-Villa
  • Luis G Guereta
  • Satish Adwani
  • Katie Linter
  • Tara Bharucha
  • Pablo Garcia-Pavia
  • Torsten B Rasmussen
  • Margherita M Calcagnino
  • Caroline B Jones
  • Hans De Wilde
  • J Toru-Kubo
  • Tiziana Felice
  • Jens Mogensen
  • Sujeev Mathur
  • Zdenka Reinhardt
  • Constantinos O'Mahony
  • Perry M Elliott
  • Rumana Z Omar
  • Juan P Kaski
  • JAMA Cardiol.2019 09;4(9):918-927. 2747608. doi: 10.1001/jamacardio.2019.2861.

金属（ロイド）で汚染された土壌に対するフォルソミアカンジダとエンキトラエウスクリプティカスの忌避行動に及ぼす気候条件の影響

Effects of climate conditions on the avoidance behavior of Folsomia candida and Enchytraeus crypticus towards metal(loid)-contaminated soils.
  • Catarina Malheiro
  • Diogo N Cardoso
  • Susana Loureiro
  • M Nazaret González-Alcaraz
  • Sci. Total Environ..2020 Jun;741:140368. S0048-9697(20)33890-0. doi: 10.1016/j.scitotenv.2020.140368.Epub 2020-06-20.

肺胞毛細血管異形成を有する2人のポーランドの新生児における遺伝子型とフェノタイプの相関

Genotype-phenotype correlation in two Polish neonates with alveolar capillary dysplasia.
  • Zuzanna Kozłowska
  • Zuzanna Owsiańska
  • Joanna P Wroblewska
  • Apolonia Kałużna
  • Andrzej Marszałek
  • Yogen Singh
  • Bartłomiej Mroziński
  • Qian Liu
  • Justyna A Karolak
  • Paweł Stankiewicz
  • Gail Deutsch
  • Marta Szymankiewicz-Bręborowicz
  • Tomasz Szczapa
  • BMC Pediatr.2020 Jun;20(1):320. 10.1186/s12887-020-02200-y. doi: 10.1186/s12887-020-02200-y.Epub 2020-06-29.

液体クロマトグラフィー・タンデム質量分析法による全血溶解液中のアザチオプリン代謝物の高感度かつ迅速な定量

Highly sensitive and rapid determination of azathioprine metabolites in whole blood lysate by liquid chromatography-tandem mass spectrometry.
  • Qiang Miao
  • Yang-Juan Bai
  • Jun-Long Zhang
  • Yi Li
  • Zhen-Zhen Su
  • Lin Yan
  • Lan-Lan Wang
  • Yuan-Gao Zou
  • J. Chromatogr. B Analyt. Technol. Biomed. Life Sci..2020 Jan;1136:121802. S1570-0232(19)31085-2. doi: 10.1016/j.jchromb.2019.121802.Epub 2019-09-13.

コラーゲンメチオニンスルホキシドとグルクロニジン/LW-1は1型糖尿病の長期生存者における冠動脈疾患のマーカーである。ジアロン試験である

Collagen methionine sulfoxide and glucuronidine/LW-1 are markers of coronary artery disease in long-term survivors with type 1 diabetes. The Dialong study.
  • Kristine B Holte
  • Mona Svanteson
  • Kristian F Hanssen
  • Kari Anne Sveen
  • Ingebjørg Seljeflot
  • Svein Solheim
  • David R Sell
  • Vincent M Monnier
  • Tore Julsrud Berg
  • PLoS ONE.2020;15(5):e0233174. PONE-D-20-00205. doi: 10.1371/journal.pone.0233174.Epub 2020-05-13.

Cynomolgus MonkeysおよびMiceにおけるCoproporphyrin I (CPI)の吸収および処分：OATP阻害の可能性を伝えるためのCPIの使用を支持する薬物動態学的証拠

Absorption and Disposition of Coproporphyrin I (CPI) in Cynomolgus Monkeys and Mice: Pharmacokinetic Evidence to Support the Use of CPI to Inform the Potential for OATP Inhibition.
  • Xiaomei Gu
  • Lifei Wang
  • Jinping Gan
  • R Marcus Fancher
  • Yuan Tian
  • Yang Hong
  • Yurong Lai
  • Michael Sinz
  • Hong Shen
  • Drug Metab. Dispos..2020 Jun;dmd.120.090670. doi: 10.1124/dmd.120.090670.Epub 2020-06-01.

ギリシャの第三次医療病院でVIM-4産生プロテウス・ミラビリスによるクローン感染が発生した

Clonal outbreak caused by VIM-4-producing Proteus mirabilis in a Greek tertiary-care hospital.
  • Efthymia Protonotariou
  • Aggeliki Poulou
  • Lida Politi
  • Georgios Meletis
  • Fani Chatzopoulou
  • Antigoni Malousi
  • Symeon Metallidis
  • Athanasios Tsakris
  • Lemonia Skoura
  • Int. J. Antimicrob. Agents.2020 Jun;:106060. S0924-8579(20)30230-2. doi: 10.1016/j.ijantimicag.2020.106060.Epub 2020-06-20.

フェンタニルはモルヒネではなく、非オピオイド系組換えヒト神経伝達物質受容体およびトランスポーターと相互作用する

Fentanyl but not Morphine Interacts with Non-Opioid Recombinant Human Neurotransmitter Receptors and Transporters.
  • Randy Torralva
  • Amy J Eshleman
  • Tracy L Swanson
  • Jennifer L Schmachtenberg
  • William E Schutzer
  • Shelley H Bloom
  • Katherine M Wolfrum
  • John F Reed
  • Aaron Janowsky
  • J. Pharmacol. Exp. Ther..2020 Jun;jpet.120.265561. doi: 10.1124/jpet.120.265561.Epub 2020-06-08.

インド・コルカタ市の下痢便サンプルの腸内マイクロバイオームとレジストームをメタゲノム解析したところ、微生物暗黒物質のシグネチャーを含む中核的で可変性のあるマイクロバイオータが明らかになった

Metagenomic analysis of gut microbiome and resistome of diarrheal fecal samples from Kolkata, India, reveals the core and variable microbiota including signatures of microbial dark matter.
  • Rituparna De
  • Asish Kumar Mukhopadhyay
  • Shanta Dutta
  • Gut Pathog.2020;12:32. 371. doi: 10.1186/s13099-020-00371-8.Epub 2020-07-07.

ラットの腸間膜動脈におけるインスリン介在性血管拡張に対するグルココルチコイドの高用量投与の効果

Effects of high doses of glucocorticoids on insulin-mediated vasodilation in the mesenteric artery of rats.
  • João Eliakim Dos S Araujo
  • Rodrigo Miguel-Dos-Santos
  • Fabrício N Macedo
  • Patrícia S Cunha
  • Milene Tavares Fontes
  • Gilson Masahiro Murata
  • Sandra Lauton-Santos
  • Valter J Santana-Filho
  • Ana Mara de O Silva
  • Angelo Roberto Antoniolli
  • Rui Curi
  • Jullyana de S S Quintans
  • Rosana de S S Barreto
  • Marcio R V Santos
  • Lucindo J Quintans-Junior
  • André S Barreto
  • PLoS ONE.2020;15(3):e0230514. PONE-D-19-25453. doi: 10.1371/journal.pone.0230514.Epub 2020-03-18.

インドのオーディシャ州、アッサム州、マニプール州の豚集団における日本脳炎ウイルスの分子疫学

Molecular epidemiology of Japanese encephalitis virus in pig population of Odisha, Assam and Manipur states of India.
  • Ankita Datey
  • Leichombam Mohindro Singh
  • Uttam Rajkhowa
  • Birendra Kumar Prusty
  • Tanuja Saswat
  • Prabhudutta Mamidi
  • Luit Moni Barkalita
  • Rupam Dutta
  • K Chandradev Sharma
  • Dinabandhu Sahoo
  • Probodh Borah
  • Sarangthem Indira Devi
  • Soma Chattopadhyay
  • Infect. Genet. Evol..2020 Sep;83:104325. S1567-1348(20)30156-8. doi: 10.1016/j.meegid.2020.104325.Epub 2020-04-20.

免疫チェックポイント阻害薬誘発性筋骨格系症状。多施設共同プロスペクティブ研究

Immune checkpoint inhibitor-induced musculoskeletal manifestations. A multicentre prospective study.
  • Dimitrios Daoussis
  • Konstantinos Melissaropoulos
  • Theodoros Dimitroulas
  • Haralambos Andreadis
  • Athina Christopoulou
  • George Douganiotis
  • Thomas Makatsoris
  • Angelos Koutras
  • Panagiotis Georgiou
  • Haralabos Kalofonos
  • Mediterr J Rheumatol.2020 Jun;31(2):239-241. mjr-31-2-239. doi: 10.31138/mjr.31.2.239.Epub 2020-04-24.

光活性フタロシアニン誘導体をベースとした抗菌剤の毒性試験

Toxicological testing of a photoactive phthalocyanine-based antimicrobial substance.
  • Kristina Kejlová
  • Hana Bendová
  • Jan Chrz
  • Markéta Dvořáková
  • Lada Svobodová
  • Alena Vlková
  • Lubomír Kubáč
  • Radka Kořínková
  • Jiří Černý
  • Danuše Očadlíková
  • Marian Rucki
  • Tuula Heinonen
  • Dagmar Jírová
  • Silvia Letašiová
  • Helena Kandarova
  • Hana Kolářová
  • Regul. Toxicol. Pharmacol..2020 May;115:104685. S0273-2300(20)30111-2. doi: 10.1016/j.yrtph.2020.104685.Epub 2020-05-23.

FGF-1は膵β細胞の機能・代謝を調節する。膵臓の機能・代謝を調節するFGF-1のin vitro試験

FGF-1 modulates pancreatic β-cell functions/metabolism: An in vitro study.
  • Pawel A Kolodziejski
  • Maciej Sassek
  • Jakub Bien
  • Natalia Leciejewska
  • Dawid Szczepankiewicz
  • Beata Szczepaniak
  • Malgorzata Wojciechowska
  • Leszek Nogowski
  • Krzysztof W Nowak
  • Mathias Z Strowski
  • Ewa Pruszynska-Oszmalek
  • Gen. Comp. Endocrinol..2020 Aug;294:113498. S0016-6480(20)30163-5. doi: 10.1016/j.ygcen.2020.113498.Epub 2020-04-29.

キサンテジオン（およびその合成に関与する中間体）は、マウス新生児モデルにおける中枢神経系へのジカウイルス移行を阻害する

Xanthenedione (and intermediates involved in their synthesis) inhibit Zika virus migration to the central nervous system in murine neonatal models.
  • Ítalo Esposti Poly da Silva
  • Milene Lopes da Silva
  • Roberto Sousa Dias
  • Edjon Gonçalves Santos
  • Maria Cecília Brangioni de Paula
  • André Silva de Oliveira
  • Ana Flávia Costa da Silveira Oliveira
  • Fabrício Marques de Oliveira
  • Cynthia Canedo da Silva
  • Róbson Ricardo Teixeira
  • Sérgio Oliveira de Paula
  • Microbes Infect..2020 Apr;S1286-4579(20)30074-5. doi: 10.1016/j.micinf.2020.04.007.Epub 2020-04-27.

多能性幹細胞からの骨形成前駆細胞の系統特異的分化により、神経堤由来の骨形成前駆細胞におけるFGF1-RUNX2の関連性が明らかになった

Lineage-specific differentiation of osteogenic progenitors from pluripotent stem cells reveals the FGF1-RUNX2 association in neural crest-derived osteoprogenitors.
  • Fahad Kidwai
  • Byron W H Mui
  • Deepika Arora
  • Kulsum Iqbal
  • Madison Hockaday
  • Luis Fernandez de Castro Diaz
  • Natasha Cherman
  • Daniel Martin
  • Vamsee D Myneni
  • Moaz Ahmad
  • Katarzyna Futrega
  • Sania Ali
  • Randall K Merling
  • Dan S Kaufman
  • Janice Lee
  • Pamela G Robey
  • Stem Cells.2020 May;doi: 10.1002/stem.3206.Epub 2020-05-22.

鈍的外傷後の表在性大腿動脈枝からの出血に対して、n-ブチルシアノアクリレートを用いた超選択的塞栓術が成功した。3例の症例報告

Successful superselective embolization with n-butyl cyanoacrylate for hemorrhage from superficial femoral artery branches following blunt trauma: Three case reports.
  • Chang Hoon Oh
  • Yook Kim
  • Jung Hwan Lee
  • Hong Rye Kim
  • Seung Je Go
  • Medicine (Baltimore).2020 Jul;99(27):e20467. 00005792-202007020-00009. doi: 10.1097/MD.0000000000020467.

SARS-CoV-2感染症の入院患者（COVID-19）を対象に、標準治療と比較してロピナビル/リトナビルおよび/またはヒドロキシクロロキンによる治療を行った場合の臨床転帰を評価するためのオーストラレーシアCOVID-19試験（ASCOT）。無作為化比較試験の試験計画書の構造化された要約

The Australasian COVID-19 Trial (ASCOT) to assess clinical outcomes in hospitalised patients with SARS-CoV-2 infection (COVID-19) treated with lopinavir/ritonavir and/or hydroxychloroquine compared to standard of care: A structured summary of a study protocol for a randomised controlled trial.
  • Justin T Denholm
  • Joshua Davis
  • David Paterson
  • Jason Roberts
  • Susan Morpeth
  • Thomas Snelling
  • Dominica Zentner
  • Megan Rees
  • Matthew O'Sullivan
  • David Price
  • Asha Bowen
  • Steven Y C Tong
  • Trials.2020 Jul;21(1):646. 10.1186/s13063-020-04576-9. doi: 10.1186/s13063-020-04576-9.Epub 2020-07-14.

口蓋と上顎歯列弓の特徴は統合失調症の男性の解剖学的マーカーになり得るか？ケースコントロール研究。口蓋は統合失調症のマーカーになりうるか？

The characteristics of palate and upper dental arch can be an anatomical marker for men with schizophrenia? Case-control study: Palate can be a marker for schizophrenia?
  • Rafael Zancan Mobile
  • Ana Clelia Roussenq
  • Melissa Rodrigues de Araujo
  • Ricardo Sbalqueiro
  • José Vinícius Bolognesi Maciel
  • Antonio Adilson Soares de Lima
  • Spec Care Dentist.2020 Jul;doi: 10.1111/scd.12488.Epub 2020-07-03.

高血圧性心疾患における左室捻転-解撚障害と血管機能障害，神経体液性活性化，運動能力低下との関連

Association of impaired left ventricular twisting-untwisting with vascular dysfunction, neurohumoral activation and impaired exercise capacity in hypertensive heart disease.
  • Ignatios Ikonomidis
  • Stavros Tzortzis
  • Helen Triantafyllidi
  • John Parissis
  • Costas Papadopoulos
  • Kyriaki Venetsanou
  • Paraskevi Trivilou
  • Ioannis Paraskevaidis
  • John Lekakis
  • Eur. J. Heart Fail..2015 Dec;17(12):1240-51. doi: 10.1002/ejhf.403.Epub 2015-10-07.

人工呼吸器関連肺炎の原因となる病原体と抗生物質に対する耐性を迅速に同定するためのポイント・オブ・ケア・マルチプレックスPCRの有用性：観察研究

Usefulness of point-of-care multiplex PCR to rapidly identify pathogens responsible for ventilator-associated pneumonia and their resistance to antibiotics: an observational study.
  • Charles-Edouard Luyt
  • Guillaume Hékimian
  • Isabelle Bonnet
  • Nicolas Bréchot
  • Matthieu Schmidt
  • Jérôme Robert
  • Alain Combes
  • Alexandra Aubry
  • Crit Care.2020 06;24(1):378. 10.1186/s13054-020-03102-2. doi: 10.1186/s13054-020-03102-2.Epub 2020-06-26.

プロテオミクス解析により、Lactuca sativa cv. Salinas の主要な代謝経路に関与するタンパク質が Lactuca serriola Accession US96UC23 よりも豊富であることが示された

Proteomics Analysis Indicates Greater Abundance of Proteins Involved in Major Metabolic Pathways in Lactuca sativa cv. Salinas than Lactuca serriola Accession US96UC23.
  • Neil D Adhikari
  • Renée L Eriksen
  • Ainong Shi
  • Beiquan Mou
  • Proteomics.2020 Jul;:e1900420. doi: 10.1002/pmic.201900420.Epub 2020-07-16.

化学療法または放射線誘発性早発卵巣不全を有する青年期および若年女性におけるホルモン補充療法。実用的な推奨事項

Hormonal replacement therapy in adolescents and young women with chemo- or radio-induced premature ovarian insufficiency: Practical recommendations.
  • A Cattoni
  • F Parissone
  • I Porcari
  • S Molinari
  • N Masera
  • M Franchi
  • S Cesaro
  • R Gaudino
  • P Passoni
  • A Balduzzi
  • Blood Rev..2020 Jul;:100730. S0268-960X(20)30080-1. doi: 10.1016/j.blre.2020.100730.Epub 2020-07-04.

耳介類肺虫の糞便および鼻腔スワブ検出のための新しい定量的リアルタイムPCR診断アッセイ、

A novel quantitative real-time PCR diagnostic assay for fecal and nasal swab detection of an otariid lungworm, .
  • Kalani M Williams
  • M K Fessler
  • R A Bloomfield
  • William D Sandke
  • Clara R Malekshahi
  • Caroline D Keroack
  • Pádraig J Duignan
  • Samantha D Torquato
  • Steven A Williams
  • Int J Parasitol Parasites Wildl.2020 Aug;12:85-92. S2213-2244(20)30043-2. doi: 10.1016/j.ijppaw.2020.04.012.Epub 2020-05-18.

顎関節骨コンポーネントの想像力学的三次元研究-矢状骨格関係、性別、年齢に応じた顎関節骨コンポーネントの研究

Imaginology Tridimensional Study of Temporomandibular Joint Osseous Components According to Sagittal Skeletal Relationship, Sex, and Age.
  • Fernanda Lobo
  • Elen de Souza Tolentino
  • Lilian Cristina Vessoni Iwaki
  • Leticia Ângelo Walewski
  • Wilton Mitsunari Takeshita
  • Mariliani Chicarelli
  • J Craniofac Surg.2019 Jul;30(5):1462-1465. 00001665-201907000-00036. doi: 10.1097/SCS.0000000000005467.

エンジェルマン症候群の非定型を呈する患者のゲノムシークエンシングにより同定されたUBE3Aの新規イントロニックバリアント

A novel intronic variant in UBE3A identified by genome sequencing in a patient with an atypical presentation of Angelman syndrome.
  • Meredith Curtis
  • Danielle Baribeau
  • Susan Walker
  • Melissa Carter
  • Gregory Costain
  • Sylvia Lamoureux
  • Eriskay Liston
  • Christian R Marshall
  • Miriam S Reuter
  • Meaghan Snell
  • Jane Summers
  • Jacob Vorstman
  • Rebekah K Jobling
  • Am. J. Med. Genet. A.2020 Jul;doi: 10.1002/ajmg.a.61740.Epub 2020-07-11.

HULCの過剰発現は、NLRP3/Caspase-1/IL-1βシグナル伝達経路阻害を介してmiR-377-5pを標的とした低酸素/再酸素化心筋細胞のアポトーシスを抑制し、心筋虚血/再灌流障害を抑制することを明らかにした

Overexpression of lncRNA HULC Attenuates Myocardial Ischemia/reperfusion Injury in Rat Models and Apoptosis of Hypoxia/reoxygenation Cardiomyocytes via Targeting miR-377-5p through NLRP3/Caspase‑1/IL‑1β Signaling Pathway Inhibition.
  • Huiqing Liang
  • Fangjiang Li
  • Huixian Li
  • Rui Wang
  • Meiling Du
  • Immunol. Invest..2020 Jul;:1-14. doi: 10.1080/08820139.2020.1791178.Epub 2020-07-17.

セルラーゼはラクトバチルス・プランタルムと相互作用し、高水分アマランスと稲ワラの混合サイレージの化学組成、細菌群集、好気性安定性に影響を与える

Cellulase interacts with Lactobacillus plantarum to affect chemical composition, bacterial communities, and aerobic stability in mixed silage of high-moisture amaranth and rice straw.
  • Lin Mu
  • Zhan Xie
  • Longxing Hu
  • Guihua Chen
  • Zhifei Zhang
  • Bioresour. Technol..2020 Jul;315:123772. S0960-8524(20)31044-0. doi: 10.1016/j.biortech.2020.123772.Epub 2020-07-02.

酢酸ナトリウムによる尿酸および乳酸産生の抑制は、フルクトース-インスリン抵抗性妊娠ラットにおける肝トリグリセリド蓄積を改善する

Suppression of uric acid and lactate production by sodium acetate ameliorates hepatic triglyceride accumulation in fructose-insulin resistant pregnant rats.
  • Adewumi O Oyabambi
  • Kehinde S Olaniyi
  • Ayodele O Soladoye
  • Lawrence A Olatunji
  • Environ. Toxicol. Pharmacol..2020 Jun;80:103452. S1382-6689(20)30128-9. doi: 10.1016/j.etap.2020.103452.Epub 2020-06-28.

Brucella abortus由来のU-Omp19はdmLT免疫原性を増加させ、大腸菌の熱-ラビルトキシン（LT）経口チャレンジに対する保護を改善する

U-Omp19 from Brucella abortus increases dmLT immunogenicity and improves protection against Escherichia coli heat-labile toxin (LT) oral challenge.
  • Lorena M Coria
  • Franco L Martinez
  • Laura A Bruno
  • Karina A Pasquevich
  • Juliana Cassataro
  • Vaccine.2020 Jul;38(32):5027-5035. S0264-410X(20)30670-8. doi: 10.1016/j.vaccine.2020.05.039.Epub 2020-06-11.

インターネットを利用した親のトレーニングプログラムの無作為化対照試験への参加に関連する親と子供の要因

Parental and child factors associated with participation in a randomised control trial of an Internet-assisted parent training programme.
  • Sturla Fossum
  • Terja Ristkari
  • Charles Cunningham
  • Patrick J McGrath
  • Auli Suominen
  • Jukka Huttunen
  • Patricia Lingley-Pottie
  • Andre Sourander
  • Child Adolesc Ment Health.2018 May;23(2):71-77. doi: 10.1111/camh.12193.Epub 2016-11-10.

モントリオールのゲイ、バイセクシャル、およびPrEP時代に男性とセックスをしたその他の男性における組み合わせHIV予防戦略。潜在クラス分析

Combination HIV Prevention Strategies Among Montreal Gay, Bisexual, and Other Men Who Have Sex with Men in the PrEP Era: A Latent Class Analysis.
  • Carla M Doyle
  • Mathieu Maheu-Giroux
  • Gilles Lambert
  • Sharmistha Mishra
  • Herak Apelian
  • Marc Messier-Peet
  • Joanne Otis
  • Daniel Grace
  • Trevor A Hart
  • David M Moore
  • Nathan J Lachowsky
  • Joseph Cox
  • AIDS Behav.2020 Jul;10.1007/s10461-020-02965-4. doi: 10.1007/s10461-020-02965-4.Epub 2020-07-09.

台湾の多発性硬化症患者におけるフィンゴリモドの安全性と有効性に関する実際のエビデンス

Real-world evidence on the safety and effectiveness of fingolimod in patients with multiple sclerosis from Taiwan.
  • Chih-Chao Yang
  • Long-Sun Ro
  • Nai-Wen Tsai
  • Chou-Ching Lin
  • Wen-Nan Huang
  • Ching-Piao Tsai
  • Thy-Sheng Lin
  • Jen-Jen Su
  • Chin-Chang Huang
  • Rong-Kuo Lyu
  • Hsin-Hua Chen
  • Wei-Ju Lee
  • Po-Lin Chen
  • Audrey Yang
  • J. Formos. Med. Assoc..2020 Jul;S0929-6646(20)30291-6. doi: 10.1016/j.jfma.2020.07.002.Epub 2020-07-12.

FHF1 発達性・てんかん性脳症の表現型を定義する

Defining the phenotype of FHF1 developmental and epileptic encephalopathy.
  • Marina Trivisano
  • Alessandro Ferretti
  • Elizabeth Bebin
  • Linda Huh
  • Gaetan Lesca
  • Aleksandra Siekierska
  • Ryo Takeguchi
  • Maryline Carneiro
  • Luca De Palma
  • Ilaria Guella
  • Kazuhiro Haginoya
  • Ruo Ming Shi
  • Atsuo Kikuchi
  • Tomoko Kobayashi
  • Julien Jung
  • Lieven Lagae
  • Mathieu Milh
  • Marie L Mathieu
  • Berge A Minassian
  • Antonio Novelli
  • Nicola Pietrafusa
  • Eri Takeshita
  • Marco Tartaglia
  • Alessandra Terracciano
  • Michelle L Thompson
  • Gregory M Cooper
  • Federico Vigevano
  • Laurent Villard
  • Nathalie Villeneuve
  • Gunnar M Buyse
  • Michelle Demos
  • Ingrid E Scheffer
  • Nicola Specchio
  • Epilepsia.2020 Jul;doi: 10.1111/epi.16582.Epub 2020-07-09.

入院中の小児の呼吸器ウイルス検出における直接免疫蛍光法（Oxoid IMAGEN®）とマルチプレックスRT-PCR DNAマイクロアレイ法（CLART® PneumoVir）の比較

Comparison of a Direct Immunofluorescence Assay (Oxoid IMAGEN®) and a Multiplex RT-PCR DNA Microarray Assay (CLART® PneumoVir) for the Detection of Respiratory Viruses in Hospitalized Children.
  • Isabel Cristina Schutz Ferreira
  • Ana Paula Alegretti
  • Fernanda De Paris
  • Rodrigo Minuto Paiva
  • Valentina Coutinho Baldoto Gava Chakr
  • J. Virol. Methods.2020 Jul;:113930. S0166-0934(20)30182-8. doi: 10.1016/j.jviromet.2020.113930.Epub 2020-07-11.

ビタミンD結合タンパク質はα細胞の機能維持とグルカゴン分泌に寄与しています

Vitamin-D-Binding Protein Contributes to the Maintenance of α Cell Function and Glucagon Secretion.
  • Katrina Viloria
  • Daniela Nasteska
  • Linford J B Briant
  • Silke Heising
  • Dean P Larner
  • Nicholas H F Fine
  • Fiona B Ashford
  • Gabriela da Silva Xavier
  • Maria Jiménez Ramos
  • Annie Hasib
  • Federica Cuozzo
  • Jocelyn E Manning Fox
  • Patrick E MacDonald
  • Ildem Akerman
  • Gareth G Lavery
  • Christine Flaxman
  • Noel G Morgan
  • Sarah J Richardson
  • Martin Hewison
  • David J Hodson
  • Cell Rep.2020 Jun;31(11):107761. S2211-1247(20)30741-5. doi: 10.1016/j.celrep.2020.107761.

マルチマーカーアプローチによる冠動脈疾患患者の心筋梗塞後の有害事象発生リスクの高い患者の特定。マルチバイオマーカー試験

Multimarker Approach to Identify Patients with Coronary Artery Disease at High Risk for Subsequent Cardiac Adverse Events: The Multi-Biomarker Study.
  • Georgiana-Aura Giurgea
  • Katrin Zlabinger
  • Alfred Gugerell
  • Dominika Lukovic
  • Bonni Syeda
  • Ljubica Mandic
  • Noemi Pavo
  • Julia Mester-Tonczar
  • Denise Traxler-Weidenauer
  • Andreas Spannbauer
  • Nina Kastner
  • Claudia Müller
  • Anahit Anvari
  • Jutta Bergler-Klein
  • Mariann Gyöngyösi
  • Biomolecules.2020 Jun;10(6). E909. doi: 10.3390/biom10060909.Epub 2020-06-15.

CYP1A1多型とグリホサートによる血清コリンエステラーゼの減少に対する感受性との相関。中国人集団の症例対照研究

Correlation between CYP1A1 polymorphisms and susceptibility to glyphosate-induced reduction of serum cholinesterase: A case-control study of a Chinese population.
  • Wenyan Cai
  • Feng Zhang
  • Lixin Zhong
  • Dongya Chen
  • Haoran Guo
  • Hengdong Zhang
  • Baoli Zhu
  • Xin Liu
  • Pestic Biochem Physiol.2020 Jan;162:23-28. S0048-3575(19)30402-X. doi: 10.1016/j.pestbp.2019.07.006.Epub 2019-08-29.

地域の保健アクターが業務で使用するための地理的アクセシビリティのモデル化を改善する

Improving geographical accessibility modeling for operational use by local health actors.
  • Felana Angella Ihantamalala
  • Vincent Herbreteau
  • Christophe Révillion
  • Mauricianot Randriamihaja
  • Jérémy Commins
  • Tanjona Andréambeloson
  • Feno H Rafenoarimalala
  • Andriamihaja Randrianambinina
  • Laura F Cordier
  • Matthew H Bonds
  • Andres Garchitorena
  • Int J Health Geogr.2020 Jul;19(1):27. 10.1186/s12942-020-00220-6. doi: 10.1186/s12942-020-00220-6.Epub 2020-07-06.

圧入チタンオッセオインテグレーションインプラントを使用した下肢骨固定式人工関節の安全性、人工関節装着時間、健康関連QOL。プロスペクティブな1年間のフォローアップコホート研究

Safety, prosthesis wearing time and health-related quality of life of lower extremity bone-anchored prostheses using a press-fit titanium osseointegration implant: A prospective one-year follow-up cohort study.
  • R Atallah
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  • L Verhamme
  • J P Frölke
  • R A Leijendekkers
  • PLoS ONE.2020;15(3):e0230027. PONE-D-19-26640. doi: 10.1371/journal.pone.0230027.Epub 2020-03-09.

2つのトランスジェニック動物プラットフォームを用いて作製されたモノクローナル抗LAMP1抗体の相補的なエピトープと良好な開発性

Complementary epitopes and favorable developability of monoclonal anti-LAMP1 antibodies generated using two transgenic animal platforms.
  • Beatrice Cameron
  • Tarik Dabdoubi
  • Laurence Berthou-Soulié
  • Marie Gagnaire
  • Isabelle Arnould
  • Anne Severac
  • Fabienne Soubrier
  • Jacqueline Morales
  • Philip A Leighton
  • William Harriman
  • Kathryn Ching
  • Yasmina Abdiche
  • Katarina Radošević
  • Thomas Bouquin
  • PLoS ONE.2020;15(7):e0235815. PONE-D-19-30443. doi: 10.1371/journal.pone.0235815.Epub 2020-07-16.

塩分誘導金ナノ粒子凝集がDNA-銀ナノクラスターの蛍光をライトアップし、カルチノエンブリオニック抗原と炭水化物抗原125の二重の癌マーカーをモニターする

Salt-induced gold nanoparticles aggregation lights up fluorescence of DNA-silver nanoclusters to monitor dual cancer markers carcinoembryonic antigen and carbohydrate antigen 125.
  • Xin Xu
  • Jiangrong Ji
  • Panpan Chen
  • Jiafeng Wu
  • Yang Jin
  • Liying Zhang
  • Shuhu Du
  • Anal. Chim. Acta.2020 Aug;1125:41-49. S0003-2670(20)30562-6. doi: 10.1016/j.aca.2020.05.027.Epub 2020-05-13.

マイコバクテリア病患者および部分的に優性のIFNγR1欠乏症を有する患者における循環および小房状樹状細胞の一過性の減少

Transient Decrease of Circulating and Tissular Dendritic Cells in Patients With Mycobacterial Disease and With Partial Dominant IFNγR1 Deficiency.
  • Laura Dotta
  • Donatella Vairo
  • Mauro Giacomelli
  • Daniele Moratto
  • Nicola Tamassia
  • William Vermi
  • Silvia Lonardi
  • Jean-Laurent Casanova
  • Jacinta Bustamante
  • Silvia Giliani
  • Raffaele Badolato
  • Front Immunol.2020;11:1161. doi: 10.3389/fimmu.2020.01161.Epub 2020-06-26.

Tephrosia vogelii抽出物とロテノイドの単離とRTgill-W1トラウト細胞株およびゼブラフィッシュ胚における毒性の検討

Isolation of the Tephrosia vogelii extract and rotenoids and their toxicity in the RTgill-W1 trout cell line and in zebrafish embryos.
  • Aziza H Said
  • Anita Solhaug
  • Morten Sandvik
  • Flower E Msuya
  • Margareth S Kyewalyanga
  • Aviti J Mmochi
  • Jan L Lyche
  • Selma Hurem
  • Toxicon.2020 Aug;183:51-60. S0041-0101(20)30244-0. doi: 10.1016/j.toxicon.2020.05.013.Epub 2020-05-23.

心臓突然死の集学的管理に遺伝子検査を統合する欧州の推奨事項

European recommendations integrating genetic testing into multidisciplinary management of sudden cardiac death.
  • Florence Fellmann
  • Carla G van El
  • Philippe Charron
  • Katarzyna Michaud
  • Heidi C Howard
  • Sarah N Boers
  • Angus J Clarke
  • Anne-Marie Duguet
  • Francesca Forzano
  • Silke Kauferstein
  • Hülya Kayserili
  • Anneke Lucassen
  • Álvaro Mendes
  • Christine Patch
  • Dragica Radojkovic
  • Emmanuelle Rial-Sebbag
  • Mary N Sheppard
  • Anne-Marie Tassé
  • Sehime G Temel
  • Antti Sajantila
  • Cristina Basso
  • Arthur A M Wilde
  • Martina C Cornel
  • Eur. J. Hum. Genet..2019 12;27(12):1763-1773. 10.1038/s41431-019-0445-y. doi: 10.1038/s41431-019-0445-y.Epub 2019-06-24.

二重に削除されたワクシニアウイルスのヒトSNF5アーミングは、中枢神経系の非定型テラトイド/ハブドイド腫瘍細胞に対して結核活性および細胞静電活性を示した

Human SNF5 arming of double-deleted vaccinia virus shows oncolytic and cytostatic activity against central nervous system atypical teratoid/rhabdoid tumor cells.
  • Satbir Thakur
  • Yibing Ruan
  • Chunfen Zhang
  • Xueqing Lun
  • Aarthi Jayanthan
  • Aru Narendran
  • Cancer Gene Ther..2020 Jul;10.1038/s41417-020-0199-2. doi: 10.1038/s41417-020-0199-2.Epub 2020-07-17.

弾性と生分解性を有するキトサン/アガロースフィルムは、わずかに酸性のpHを有しており、人工皮膚移植片として再生医療への応用が期待されています

Elastic and biodegradable chitosan/agarose film revealing slightly acidic pH for potential applications in regenerative medicine as artificial skin graft.
  • Vladyslav Vivcharenko
  • Aleksandra Benko
  • Krzysztof Palka
  • Michal Wojcik
  • Agata Przekora
  • Int. J. Biol. Macromol..2020 Jul;S0141-8130(20)33853-8. doi: 10.1016/j.ijbiomac.2020.07.099.Epub 2020-07-15.

中枢神経系におけるNMDA誘導性一酸化窒素生成とCREB活性化は真核生物の伸長因子2キナーゼに依存している

NMDA-induced nitric oxide generation and CREB activation in central nervous system is dependent on eukaryotic elongation factor 2 kinase.
  • Luis Felipe Homem Gladulich
  • Maria Carolina Peixoto-Rodrigues
  • Paula Campello-Costa
  • Roberto Paes-de-Carvalho
  • Marcelo Cossenza
  • Biochim Biophys Acta Mol Cell Res.2020 Jun;1867(10):118783. S0167-4889(20)30141-5. doi: 10.1016/j.bbamcr.2020.118783.Epub 2020-06-20.

インプラント支持型フルアーチ人工関節のためのダイナミックナビゲーションシステムワークフローの精度。症例シリーズ

Accuracy of Dynamic Navigation System Workflow for Implant Supported Full Arch Prosthesis: A Case Series.
  • Luigi V Stefanelli
  • George A Mandelaris
  • Alessio Franchina
  • Nicola Pranno
  • Michele Pagliarulo
  • Francesca Cera
  • Fabio Maltese
  • Francesca De Angelis
  • Stefano Di Carlo
  • Int J Environ Res Public Health.2020 Jul;17(14). E5038. doi: 10.3390/ijerph17145038.Epub 2020-07-13.

MicroRNA-223は、健康な網膜と変性網膜の網膜機能と炎症を制御している

MicroRNA-223 Regulates Retinal Function and Inflammation in the Healthy and Degenerating Retina.
  • Nilisha Fernando
  • Josephine H C Wong
  • Shannon Das
  • Catherine Dietrich
  • Riemke Aggio-Bruce
  • Adrian V Cioanca
  • Yvette Wooff
  • Joshua A Chu-Tan
  • Ulrike Schumann
  • Chinh Ngo
  • Rohan W Essex
  • Camilla Dorian
  • Sarah A Robertson
  • Si Ming Man
  • Jan Provis
  • Riccardo Natoli
  • Front Cell Dev Biol.2020;8:516. doi: 10.3389/fcell.2020.00516.Epub 2020-06-26.

投与後、D-フェンフルラミンを投与することで、BALB/c、C57BL/6、SWRマウスの甘味摂取量が減少することがわかった

Acute d-fenfluramine, but not fluoxetine decreases sweet intake in BALB/c, C57BL/6 and SWR inbred mouse strains.
  • Tatjana Mustac
  • Asnat Yuabov
  • Jason Macanian
  • Sonya Aminov
  • David Fazylov
  • Eden Ben Lulu
  • Mirna Nashed
  • Ahmed Albakry
  • Bruneskidvi Jean-Philippe-Morisset
  • Richard J Bodnar
  • Physiol. Behav..2020 Jun;224:113029. S0031-9384(20)30343-7. doi: 10.1016/j.physbeh.2020.113029.Epub 2020-06-24.

肺線維症におけるケモカイン受容体2を標的とした分子イメージング

Chemokine Receptor 2-targeted Molecular Imaging in Pulmonary Fibrosis.
  • Steven L Brody
  • Sean P Gunsten
  • Hannah P Luehmann
  • Debbie H Sultan
  • Michelle Hoelscher
  • Gyu Seong Heo
  • Jiehong Pan
  • Jeffrey R Koenitzer
  • Ethan C Lee
  • Tao Huang
  • Cedric Mpoy
  • Shuchi Guo
  • Richard Laforest
  • Amber Salter
  • Tonya D Russell
  • Adrian Shifren
  • Christophe Combadiere
  • Kory J Lavine
  • Daniel Kreisel
  • Benjamin D Humphreys
  • Buck E Rogers
  • David S Gierada
  • Derek E Byers
  • Robert J Gropler
  • Delphine L Chen
  • Jeffrey J Atkinson
  • Yongjian Liu
  • Am. J. Respir. Crit. Care Med..2020 Jul;doi: 10.1164/rccm.202004-1132OC.Epub 2020-07-16.

潰瘍性大腸炎の治療におけるプロバイオティクスの長期効果。臨床研究

The long-term effects of probiotics in the therapy of ulcerative colitis: A clinical study.
  • Vincenzo Davide Palumbo
  • Marcello Romeo
  • Antonella Marino Gammazza
  • Francesco Carini
  • Provvidenza Damiani
  • Giuseppe Damiano
  • Salvatore Buscemi
  • Attilio Ignazio Lo Monte
  • Alice Gerges-Geagea
  • Abdo Jurjus
  • Giovanni Tomasello
  • Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub.2016 Sep;160(3):372-7. doi: 10.5507/bp.2016.044.Epub 2016-09-13.

Ga3+8Sm3+2, Ga3+8Tb3+2メタラクラウンは、生理学的に関連する温度で動作する非常に有望なレシオメトリック発光分子ナノ温度計である

[Ga3+8Sm3+2, Ga3+8Tb3+2] metallacrowns are highly promising ratiometric luminescent molecular nanothermometers operating at physiologically relevant temperatures.
  • Elvin V Salerno
  • Justyna Zeler
  • Svetlana V Eliseeva
  • Miguel A Hernández-Rodríguez
  • Albano N Carneiro Neto
  • Stéphane Petoud
  • Vincent Louis Pecoraro
  • Luís D Carlos
  • Chemistry.2020 Jul;doi: 10.1002/chem.202003239.Epub 2020-07-14.

プロバイオティクスであるラクトバチルスとビフィズス菌の長期使用は，パウチ炎の発生と重症度に対する予防効果がある：無作為化プロスペクティブ研究

Long-term use of probiotics Lactobacillus and Bifidobacterium has a prophylactic effect on the occurrence and severity of pouchitis: a randomized prospective study.
  • Banasiewicz Tomasz
  • Stojcev Zoran
  • Walkowiak Jarosław
  • Marciniak Ryszard
  • Grochowalski Marcin
  • Burdyński Robert
  • Krokowicz Piotr
  • Krokowicz Lukasz
  • Paszkowski Jacek
  • Gronek Piotr
  • Pyda Przemysław
  • Drews Michał
  • Biomed Res Int.2014;2014:208064. doi: 10.1155/2014/208064.Epub 2014-01-21.

世界/自己のアンビバレンス。精神病体験の異なるサブセットに共通するメカニズム？安静時fMRIと症状の関連性

World/self ambivalence: A shared mechanism in different subsets of psychotic experiences? Linking symptoms with resting-state fMRI.
  • Stefano Damiani
  • Laura Fusar-Poli
  • Natascia Brondino
  • Umberto Provenzani
  • Helen Baldwin
  • Paolo Fusar-Poli
  • Pierluigi Politi
  • Psychiatry Res Neuroimaging.2020 05;299:111068. S0925-4927(20)30040-8. doi: 10.1016/j.pscychresns.2020.111068.Epub 2020-03-18.

現代の免疫治療薬や生物薬剤学における治療用ペプチドの定量のためのシンプルで迅速なLC-MS/MSおよびCE-MS/MS分析戦略

A simple and rapid LC-MS/MS and CE-MS/MS analytical strategy for the determination of therapeutic peptides in modern immunotherapeutics and biopharmaceutics.
  • Juraj Piestansky
  • Peter Barath
  • Petra Majerova
  • Jaroslav Galba
  • Peter Mikus
  • Branislav Kovacech
  • Andrej Kovac
  • J Pharm Biomed Anal.2020 Jun;189:113449. S0731-7085(20)31335-2. doi: 10.1016/j.jpba.2020.113449.Epub 2020-06-25.

疾患サーベイランスと分析のための空間分解能とスケールを超えた情報の違い。ブラジルにおける内臓リーシュマニア症の事例

Information differences across spatial resolutions and scales for disease surveillance and analysis: The case of Visceral Leishmaniasis in Brazil.
  • Joseph L Servadio
  • Gustavo Machado
  • Julio Alvarez
  • Francisco Edilson de Ferreira Lima Júnior
  • Renato Vieira Alves
  • Matteo Convertino
  • PLoS ONE.2020;15(7):e0235920. PONE-D-20-06883. doi: 10.1371/journal.pone.0235920.Epub 2020-07-17.

血清中抗p53抗体は、膵臓の管内乳頭粘液性新生物の組織学的悪性度を予測するマーカーとして機能する可能性がある

Serum Anti-p53 Antibody Can Serve as a Predictive Marker for Histological Grade of Intraductal Papillary Mucinous Neoplasms of the Pancreas.
  • Tatsuo Hata
  • Masamichi Mizuma
  • Fuyuhiko Motoi
  • Masahiro Iseki
  • Yuko Omori
  • Hiroki Hayashi
  • Kei Nakagawa
  • Takanori Morikawa
  • Takashi Kamei
  • Takeshi Naitoh
  • Toru Furukawa
  • Michiaki Unno
  • Pancreas.2020 Jul;49(6):768-773. doi: 10.1097/MPA.0000000000001570.

アルデヒド脱水素酵素2はAkt-mTOR経路を介してオートファジーを制御し、低体温機械灌流における腎虚血再灌流傷害を緩和する

Aldehyde dehydrogenase 2 regulates autophagy via the Akt-mTOR pathway to mitigate renal ischemia-reperfusion injury in hypothermic machine perfusion.
  • Danni Lin
  • Tao Xiang
  • Qiangmin Qiu
  • Junto Leung
  • Junjie Xu
  • Wei Zhou
  • Qianchao Hu
  • Jianan Lan
  • Zhongzhong Liu
  • Zibiao Zhong
  • Yanfeng Wang
  • Qifa Ye
  • Life Sci..2020 Jul;253:117705. S0024-3205(20)30453-7. doi: 10.1016/j.lfs.2020.117705.Epub 2020-04-22.

強力なPDE10A阻害剤MP-10（PF-2545920）は、LPS誘発神経炎症とMPTP誘発パーキンソン病マウスモデルにおけるミクログリアの活性化を抑制する

The Potent PDE10A Inhibitor MP-10 (PF-2545920) Suppresses Microglial Activation in LPS-Induced Neuroinflammation and MPTP-Induced Parkinson's Disease Mouse Models.
  • Do-Yeon Kim
  • Jin-Sun Park
  • Yea-Hyun Leem
  • Jung-Eun Park
  • Hee-Sun Kim
  • J Neuroimmune Pharmacol.2020 Jul;10.1007/s11481-020-09943-6. doi: 10.1007/s11481-020-09943-6.Epub 2020-07-15.

シリクリスチンAはNrf2-HO-1/SOD2経路を活性化し、GLUTag細胞におけるエストロゲン受容体αのアップレギュレーションを介してアポトーシスを抑制し、GLP-1産生を改善します

Silychristin A activates Nrf2-HO-1/SOD2 pathway to reduce apoptosis and improve GLP-1 production through upregulation of estrogen receptor α in GLUTag cells.
  • Jinyu Wang
  • Xiaoying Zhang
  • Luxin Zhang
  • Tingxu Yan
  • Bo Wu
  • Fanxing Xu
  • Ying Jia
  • Eur. J. Pharmacol..2020 Jun;881:173236. S0014-2999(20)30328-9. doi: 10.1016/j.ejphar.2020.173236.Epub 2020-06-01.

システマティックレビュー。組織再生における先進治療薬（ATMP）としての間質血管画分（SVF）と脱細胞化細胞外マトリックス（ECM）の全原性使用

Systematic Review: Allogenic Use of Stromal Vascular Fraction (SVF) and Decellularized Extracellular Matrices (ECM) as Advanced Therapy Medicinal Products (ATMP) in Tissue Regeneration.
  • Pietro Gentile
  • Aris Sterodimas
  • Jacopo Pizzicannella
  • Laura Dionisi
  • Domenico De Fazio
  • Claudio Calabrese
  • Simone Garcovich
  • Int J Mol Sci.2020 Jul;21(14). E4982. doi: 10.3390/ijms21144982.Epub 2020-07-15.

ニコチンアミド/ストレプトゾトシン誘発ウィスター糖尿病ラットにおける果皮ヒドロエタノール抽出物、ヘスペリジンおよびケルセチンの抗糖尿病活性、抗酸化作用および作用機序

Antidiabetic Potency, Antioxidant Effects, and Mode of Actions of Fruit Peel Hydroethanolic Extract, Hesperidin, and Quercetin in Nicotinamide/Streptozotocin-Induced Wistar Diabetic Rats.
  • Alaa M Ali
  • Mohamed Abdel Gabbar
  • Sanaa M Abdel-Twab
  • Eman M Fahmy
  • Hossam Ebaid
  • Ibrahim M Alhazza
  • Osama M Ahmed
  • Oxid Med Cell Longev.2020;2020:1730492. doi: 10.1155/2020/1730492.Epub 2020-06-20.

インビボ共焦点顕微鏡を用いたマイクロニューロマスの可視化。神経障害性角膜痛の診断のための客観的なバイオマーカーとなるか？

Visualization of micro-neuromas by using in vivo confocal microscopy: An objective biomarker for the diagnosis of neuropathic corneal pain?
  • Hamid-Reza Moein
  • Anam Akhlaq
  • Gabriela Dieckmann
  • Alessandro Abbouda
  • Nicholas Pondelis
  • Zeina Salem
  • Rodrigo T Müller
  • Andrea Cruzat
  • Bernardo M Cavalcanti
  • Arsia Jamali
  • Pedram Hamrah
  • Ocul Surf.2020 Jul;S1542-0124(20)30111-7. doi: 10.1016/j.jtos.2020.07.004.Epub 2020-07-11.

腫瘍性顎再建における即時歯科インプラント埋入。ワークフローの最適化による完全な歯科リハビリテーションまでの時間の短縮

Immediate Dental Implantation in Oncologic Jaw Reconstruction: Workflow Optimization to Decrease Time to Full Dental Rehabilitation.
  • Robert J Allen
  • Deana S Shenaq
  • Evan B Rosen
  • Snehal G Patel
  • Ian Ganly
  • Jay O Boyle
  • Jonas A Nelson
  • Evan Matros
  • Plast Reconstr Surg Glob Open.2019 Jan;7(1):e2100. doi: 10.1097/GOX.0000000000002100.Epub 2019-01-14.

レビュー。子どものサービスから大人のサービスへの移行：イングランドにおける注意欠陥多動性障害の若者のためのガイドラインとプロトコールのレビュー

Review: Transition from children's to adult services: a review of guidelines and protocols for young people with attention deficit hyperactivity disorder in England.
  • Helen Eke
  • Astrid Janssens
  • Tamsin Ford
  • Child Adolesc Ment Health.2019 May;24(2):123-132. doi: 10.1111/camh.12301.Epub 2018-09-12.

慢性リンパ性白血病患者における皮膚扁平上皮がんに関連する臨床的および生物学的因子の描出

Delineation of clinical and biological factors associated with cutaneous squamous cell carcinoma amongst chronic lymphocytic leukemia patients.
  • Geffen Kleinstern
  • Abdul Rishi
  • Sara J Achenbach
  • Kari G Rabe
  • Neil E Kay
  • Tait D Shanafelt
  • Wei Ding
  • Joe F Leis
  • Aaron D Norman
  • Timothy G Call
  • James R Cerhan
  • Sameer A Parikh
  • Christian L Baum
  • Susan L Slager
  • J. Am. Acad. Dermatol..2020 Jul;S0190-9622(20)32196-4. doi: 10.1016/j.jaad.2020.06.1024.Epub 2020-07-15.

臨床的に鑑別された精巣下降異常：クリプトルキディズムと退行性精巣におけるヒトクレマスターマッスルのミオシンアイソフォームの構造と発現の異常

Clinically Differentiated Abnormalities of the Architecture and Expression of Myosin Isoforms of the Human Cremaster Muscle in Cryptorchidism and Retractile Testis.
  • Francesco Molinaro
  • Giulia Fusi
  • Margherita Aglianò
  • Nila Volpi
  • Daniela Franci
  • Paola Lorenzoni
  • Maddalena Messina
  • Angela Galgano
  • Francesco Grasso
  • Carlotta Plessi
  • Mario Messina
  • Rossella Angotti
  • Urol. Int..2020 Jul;:1-11. 000508432. doi: 10.1159/000508432.Epub 2020-07-16.

注意欠陥/多動性障害を持つ子供の行動パフォーマンスの潜在的な客観的な予測因子としての宿泊施設と瞳孔のダイナミクス

Accommodation and pupil dynamics as potential objective predictors of behavioural performance in children with attention-deficit/hyperactivity disorder.
  • Beatriz Redondo
  • Jesús Vera
  • Ruben Molina
  • José Antonio Garcia
  • Andrés Catena
  • Antonio Muñoz-Hoyos
  • Raimundo Jimenez
  • Vision Res..2020 Jul;175:32-40. S0042-6989(20)30111-5. doi: 10.1016/j.visres.2020.06.005.Epub 2020-07-15.

レーザー加速陽子線を用いたゼブラフィッシュ胚照射のフィージビリティスタディ

A feasibility study of zebrafish embryo irradiation with laser-accelerated protons.
  • Thomas F Rösch
  • Zoltán Szabó
  • Daniel Haffa
  • Jianhui Bin
  • Szilvia Brunner
  • Franz S Englbrecht
  • Anna A Friedl
  • Ying Gao
  • Jens Hartmann
  • Peter Hilz
  • Christian Kreuzer
  • Florian H Lindner
  • Tobias M Ostermayr
  • Róbert Polanek
  • Martin Speicher
  • Emília R Szabó
  • Derya Taray
  • Tünde Tőkés
  • Matthias Würl
  • Katia Parodi
  • Katalin Hideghéty
  • Jörg Schreiber
  • Rev Sci Instrum.2020 Jun;91(6):063303. doi: 10.1063/5.0008512.

肝および全身性アンジオポエチン様3、肝性ビタミンD受容体発現、肥満におけるNAFLDとの関係

Relationship between hepatic and systemic angiopoietin-like 3, hepatic Vitamin D receptor expression and NAFLD in obesity.
  • Ilaria Barchetta
  • Flavia A Cimini
  • Caterina Chiappetta
  • Laura Bertoccini
  • Valentina Ceccarelli
  • Danila Capoccia
  • Melania Gaggini
  • Claudio Di Cristofano
  • Carlo Della Rocca
  • Gianfranco Silecchia
  • Frida Leonetti
  • Andrea Lenzi
  • Amalia Gastaldelli
  • Maria G Cavallo
  • Liver Int..2020 Jun;doi: 10.1111/liv.14554.Epub 2020-06-08.

非小細胞肺癌脳転移に対する定位照射：大規模シリーズにおける局所制御と脳制御の評価

Stereotactic irradiation of non-small cell lung cancer brain metastases: evaluation of local and cerebral control in a large series.
  • Etienne Fessart
  • Raphaëlle Mouttet Audouard
  • Florence Le Tinier
  • Bernard Coche-Dequeant
  • Thomas Lacornerie
  • Emmanuelle Tresch
  • Arnaud Scherpereel
  • Eric Lartigau
  • Xavier Mirabel
  • David Pasquier
  • Sci Rep.2020 Jul;10(1):11201. 10.1038/s41598-020-68209-6. doi: 10.1038/s41598-020-68209-6.Epub 2020-07-08.

生の鶏肉を取り扱う際のクロスコンタミネーションに関連したヒトカンピロバクター症。オーストラリアにおける介入シナリオ分析の指針となる定量的リスク評価の適用

Human campylobacteriosis related to cross-contamination during handling of raw chicken meat: Application of quantitative risk assessment to guide intervention scenarios analysis in the Australian context.
  • Ihab Habib
  • John Coles
  • Mark Fallows
  • Stan Goodchild
  • Int. J. Food Microbiol..2020 Jun;332:108775. S0168-1605(20)30269-5. doi: 10.1016/j.ijfoodmicro.2020.108775.Epub 2020-06-30.

ラット初代培養海馬神経細胞におけるペルオキシソーム増殖因子活性化受容体（PPAR）-γがAβ神経毒誘発性電気生理学的変化を修飾することを明らかにした

Peroxisome Proliferator-activated Receptor (PPAR)-γ Modifies Aβ Neurotoxin-induced Electrophysiological Alterations in Rat Primary Cultured Hippocampal Neurons.
  • Farideh Bahrami
  • Alireza Asgari
  • Narges Hosseinmardi
  • Mahyar Janahmadi
  • Iran J Pharm Res.2019;18(3):1403-1418. doi: 10.22037/ijpr.2019.1100783.

膵臓酵素を含むサンプル中のエンテロウイルス RNA のカプセル化と非カプセル化の検出の違い-糖尿病研究のための重要性

Differential Detection of Encapsidated versus Unencapsidated Enterovirus RNA in Samples Containing Pancreatic Enzymes-Relevance for Diabetes Studies.
  • Maarit Oikarinen
  • Lori Bertolet
  • Antonio Toniolo
  • Sami Oikarinen
  • Jutta E Laiho
  • Alberto Pugliese
  • Richard E Lloyd
  • Heikki Hyöty
  • The nPOD-V Study Group
  • Viruses.2020 Jul;12(7). E747. doi: 10.3390/v12070747.Epub 2020-07-11.

Hsa_circ_0088036 は、関節リウマチにおける miR-140-3p のスポンギングと SIRT 1 発現のアップレギュレーションにより、線維芽細胞様滑膜細胞の増殖と遊走を促進します

Hsa_circ_0088036 promotes the proliferation and migration of fibroblast-like synoviocytes by sponging miR-140-3p and upregulating SIRT 1 expression in rheumatoid arthritis.
  • Shuping Zhong
  • Qingqing Ouyang
  • Dingji Zhu
  • Qin Huang
  • Jinjun Zhao
  • Meida Fan
  • Yujie Cai
  • Min Yang
  • Mol. Immunol..2020 Jul;125:131-139. S0161-5890(20)30410-7. doi: 10.1016/j.molimm.2020.07.004.Epub 2020-07-13.

ニューラフェレーシス治療のin vitro評価：下顎骨転移に対する新しいアプローチ

Evaluation of neurapheresis therapy in vitro: a novel approach for the treatment of leptomeningeal metastases.
  • Tiffany Ejikeme
  • George C de Castro
  • Katelyn Ripple
  • Yutong Chen
  • Charles Giamberardino
  • Andrew Bartuska
  • Gordon Smilnak
  • Choiselle Marius
  • Jane-Valeriane Boua
  • Pakawat Chongsathidkiet
  • Sarah Hodges
  • Promila Pagadala
  • Laura Zitella Verbick
  • Aaron R McCabe
  • Shivanand P Lad
  • Neurooncol Adv.2020 Jan-Dec;2(1):vdaa052. vdaa052. doi: 10.1093/noajnl/vdaa052.Epub 2020-04-18.

マウスにおける2,4-ジクロロフェノキシ酢酸(2,4-D)の急性吸入暴露に伴う頬の損傷の評価

Evaluation of buccal damage associated with acute inhalation exposure to 2,4-dichlorophenoxyacetic acid (2,4-D) in mice.
  • José Luiz Santos Parizi
  • Amanda Jodas Tolardo
  • Ana Carolina Gomes Lisboa
  • Bruna Barravieira
  • Fabíola de Azevedo Mello
  • Renata Calciolari Rossi
  • Gisele Alborghetti Nai
  • BMC Vet. Res..2020 Jul;16(1):244. 10.1186/s12917-020-02461-w. doi: 10.1186/s12917-020-02461-w.Epub 2020-07-14.

アンジオポエチン様タンパク質3（ANGPTL3）は、内皮リパーゼ依存性のVLDLクリアランスを介してLDL-コレステロールレベルを制御します

Angiopoietin-like protein 3 (ANGPTL3) governs LDL-cholesterol levels through endothelial lipase-dependent VLDL clearance.
  • Rene C Adam
  • Ivory J Mintah
  • Corey A Alexa-Braun
  • Lisa M Shihanian
  • Joseph S Lee
  • Poulabi Banerjee
  • Sara C Hamon
  • Hye In Kim
  • Jonathan C Cohen
  • Helen H Hobbs
  • Cristopher Van Hout
  • Jesper Gromada
  • Andrew J Murphy
  • George D Yancopoulos
  • Mark W Sleeman
  • Viktoria Gusarova
  • J. Lipid Res..2020 Jul;jlr.RA120000888. doi: 10.1194/jlr.RA120000888.Epub 2020-07-09.

康愛静注に含まれる複数の循環性アルカロイドおよびサポニンがヒトのチトクロームP450およびUDP-グルクロン酸転移酵素アイソザイムを阻害する：薬物-薬物相互作用の可能性

Multiple circulating alkaloids and saponins from intravenous Kang-Ai injection inhibit human cytochrome P450 and UDP-glucuronosyltransferase isozymes: potential drug-drug interactions.
  • Zifei Qin
  • Mengmeng Jia
  • Jing Yang
  • Han Xing
  • Zhao Yin
  • Zhihong Yao
  • Xiaojian Zhang
  • Xinsheng Yao
  • Chin Med.2020;15:69. 349. doi: 10.1186/s13020-020-00349-3.Epub 2020-07-06.

1MeV/c^{2}までの質量を持つボソニック超弱相互作用質量粒子の初探索

First Search for Bosonic Superweakly Interacting Massive Particles with Masses up to 1  MeV/c^{2} with GERDA.
  • M Agostini
  • A M Bakalyarov
  • M Balata
  • I Barabanov
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  • C Bauer
  • E Bellotti
  • S Belogurov
  • A Bettini
  • L Bezrukov
  • D Borowicz
  • E Bossio
  • V Bothe
  • V Brudanin
  • R Brugnera
  • A Caldwell
  • C Cattadori
  • A Chernogorov
  • T Comellato
  • V D'Andrea
  • E V Demidova
  • N Di Marco
  • E Doroshkevich
  • V Egorov
  • F Fischer
  • M Fomina
  • A Gangapshev
  • A Garfagnini
  • C Gooch
  • P Grabmayr
  • V Gurentsov
  • K Gusev
  • J Hakenmüller
  • S Hemmer
  • R Hiller
  • W Hofmann
  • M Hult
  • L V Inzhechik
  • J Janicskó Csáthy
  • J Jochum
  • M Junker
  • V Kazalov
  • Y Kermaïdic
  • H Khushbakht
  • T Kihm
  • I V Kirpichnikov
  • A Klimenko
  • R Kneißl
  • K T Knöpfle
  • O Kochetov
  • V N Kornoukhov
  • P Krause
  • V V Kuzminov
  • M Laubenstein
  • A Lazzaro
  • M Lindner
  • I Lippi
  • A Lubashevskiy
  • B Lubsandorzhiev
  • G Lutter
  • C Macolino
  • B Majorovits
  • W Maneschg
  • M Miloradovic
  • R Mingazheva
  • M Misiaszek
  • P Moseev
  • I Nemchenok
  • K Panas
  • L Pandola
  • K Pelczar
  • L Pertoldi
  • P Piseri
  • A Pullia
  • C Ransom
  • L Rauscher
  • S Riboldi
  • N Rumyantseva
  • C Sada
  • F Salamida
  • S Schönert
  • J Schreiner
  • M Schütt
  • A-K Schütz
  • O Schulz
  • M Schwarz
  • B Schwingenheuer
  • O Selivanenko
  • E Shevchik
  • M Shirchenko
  • H Simgen
  • A Smolnikov
  • D Stukov
  • A A Vasenko
  • A Veresnikova
  • C Vignoli
  • K von Sturm
  • T Wester
  • C Wiesinger
  • M Wojcik
  • E Yanovich
  • B Zatschler
  • I Zhitnikov
  • S V Zhukov
  • D Zinatulina
  • A Zschocke
  • A J Zsigmond
  • K Zuber
  • G Zuzel
  • Phys. Rev. Lett..2020 Jul;125(1):011801. doi: 10.1103/PhysRevLett.125.011801.

核質タンパク質NOP2/NSUN1は、Tatと競合してTARの結合やメチル化を行うことで、HIV-1の転写を抑制し、ウイルス潜伏を促進する

Nucleolar protein NOP2/NSUN1 suppresses HIV-1 transcription and promotes viral latency by competing with Tat for TAR binding and methylation.
  • Weili Kong
  • Ayan Biswas
  • Dawei Zhou
  • Guillaume Fiches
  • Koh Fujinaga
  • Netty Santoso
  • Jian Zhu
  • PLoS Pathog..2020 03;16(3):e1008430. PPATHOGENS-D-19-01970. doi: 10.1371/journal.ppat.1008430.Epub 2020-03-16.

RSVのグローバルな分子多様性-「INFORM RSV」の研究

Global molecular diversity of RSV - the "INFORM RSV" study.
  • Annefleur C Langedijk
  • Robert Jan Lebbink
  • Christiana Naaktgeboren
  • Anouk Evers
  • Marco C Viveen
  • Anne Greenough
  • Terho Heikkinen
  • Renato T Stein
  • Peter Richmond
  • Federico Martinón-Torres
  • Marta Nunes
  • Mitsuaki Hosoya
  • Christian Keller
  • Monika Bauck
  • Robert Cohen
  • Jesse Papenburg
  • Jeffrey Pernica
  • Marije P Hennus
  • Hong Jin
  • David E Tabor
  • Andrev Tovchigrechko
  • Alexey Ruzin
  • Michael E Abram
  • Deidre Wilkins
  • Joanne G Wildenbeest
  • Leyla Kragten-Tabatabaie
  • Frank E J Coenjaerts
  • Mark T Esser
  • Louis J Bont
  • BMC Infect. Dis..2020 Jun;20(1):450. 10.1186/s12879-020-05175-4. doi: 10.1186/s12879-020-05175-4.Epub 2020-06-26.

日本人患者におけるセメントレスユニコンパートメント膝関節形成術後の脛骨プラトー骨折のリスクを脛骨の形状と大きさが予測する

Tibial shape and size predicts the risk of tibial plateau fracture after cementless unicompartmental knee arthroplasty in Japanese patients.
  • Takafumi Hiranaka
  • Ryo Yoshikawa
  • Kenjiro Yoshida
  • Kazuhiko Michishita
  • Takehiro Nishimura
  • Shingo Nitta
  • Kenichiro Takashiba
  • David Murray
  • Bone Joint J.2020 Jul;102-B(7):861-867. doi: 10.1302/0301-620X.102B7.BJJ-2019-1754.R1.

近赤外・中赤外域でのメタンと二酸化炭素の検出を目的とした抗レゾナント中空ファイバを用いたデュアルガスセンサ

Antiresonant Hollow-Core Fiber-Based Dual Gas Sensor for Detection of Methane and Carbon Dioxide in the Near- and Mid-Infrared Regions.
  • Piotr Jaworski
  • Paweł Kozioł
  • Karol Krzempek
  • Dakun Wu
  • Fei Yu
  • Piotr Bojęś
  • Grzegorz Dudzik
  • Meisong Liao
  • Krzysztof Abramski
  • Jonathan Knight
  • Sensors (Basel).2020 Jul;20(14). E3813. doi: 10.3390/s20143813.Epub 2020-07-08.

高血圧ラットに誘発された後虚血性急性腎障害における高気圧酸素前処理とNADPH酸化酵素阻害の役割

Hyperbaric oxygen preconditioning and the role of NADPH oxidase inhibition in postischemic acute kidney injury induced in spontaneously hypertensive rats.
  • Sanjin Kovacevic
  • Milan Ivanov
  • Zoran Miloradovic
  • Predrag Brkic
  • Una Jovana Vajic
  • Maja Zivotic
  • Nevena Mihailovic-Stanojevic
  • Djurdjica Jovovic
  • Danijela Karanovic
  • Rada Jeremic
  • Jelena Nesovic-Ostojic
  • PLoS ONE.2020;15(1):e0226974. PONE-D-19-14602. doi: 10.1371/journal.pone.0226974.Epub 2020-01-08.

心房細動における脳卒中予防のためのウォッチマンとアンプラッツァー装置を比較したメタアナリシス

Meta-Analysis Comparing Watchman and Amplatzer Devices for Stroke Prevention in Atrial Fibrillation.
  • Indranill Basu Ray
  • Dibbendhu Khanra
  • Sumit Shah
  • Sudhanva Char
  • Xiaoming Jia
  • Wilson Lam
  • Nilesh Mathuria
  • Mehdi Razavi
  • Bhavna Jain
  • Dhanunjaya Lakkireddy
  • Saibal Kar
  • Andrea Natale
  • Adedayo Adeboye
  • John Lynn Jefferies
  • Sripal Bangalore
  • Samuel Asirvatham
  • Mohammad Saeed
  • Front Cardiovasc Med.2020;7:89. doi: 10.3389/fcvm.2020.00089.Epub 2020-06-22.

疼痛コントロールにおけるカンナビノイド系の役割。基礎的および臨床的意味合い

The Role of the Cannabinoid System in Pain Control: Basic and Clinical Implications.
  • John Wolf
  • Ivan Urits
  • Vwaire Orhurhu
  • Jacquelin Peck
  • Mariam Salisu Orhurhu
  • Stephen Giacomazzi
  • Daniel Smoots
  • Charlie Piermarini
  • Laxmaiah Manchikanti
  • Alan D Kaye
  • Rachel J Kaye
  • Omar Viswanath
  • Curr Pain Headache Rep.2020 Jun;24(7):35. 10.1007/s11916-020-00873-9. doi: 10.1007/s11916-020-00873-9.Epub 2020-06-06.

狭範囲UV-LEDの低エネルギー照射は、老化促進マウスprone6におけるビタミンD欠乏に伴うオステオサルコペニアを予防する

Low energy irradiation of narrow-range UV-LED prevents osteosarcopenia associated with vitamin D deficiency in senescence-accelerated mouse prone 6.
  • Kazuya Makida
  • Yoshihiro Nishida
  • Daigo Morita
  • Satoshi Ochiai
  • Yoshitoshi Higuchi
  • Taisuke Seki
  • Kunihiro Ikuta
  • Naoki Ishiguro
  • Sci Rep.2020 Jul;10(1):11892. 10.1038/s41598-020-68641-8. doi: 10.1038/s41598-020-68641-8.Epub 2020-07-17.

ポリプロピレン-高密度ポリエチレンの再生プラスチック樹脂中の好ましくない臭気の原因となる揮発性化合物の固相マイクロ抽出法による分析

Analysis of volatile compounds causing undesirable odors in a polypropylene - high-density polyethylene recycled plastic resin with solid-phase microextraction.
  • Jon Fuller
  • David White
  • Huijun Yi
  • Jason Colley
  • Zane Vickery
  • Shaoyang Liu
  • Chemosphere.2020 Jul;260:127589. S0045-6535(20)31784-7. doi: 10.1016/j.chemosphere.2020.127589.Epub 2020-07-09.

Long: bilineal inv(16) myeloid and del(9) lmphoid blast crisisを有するCMLの分子追跡とCD19指示のCAR-T療法に対する持続的な反応

Long: molecular tracking of CML with bilineal inv(16) myeloid and del(9) lymphoid blast crisis and durable response to CD19-directed CAR-T therapy.
  • Vinayak Venkataraman
  • Keagan S Casey
  • Maristela Onozato
  • Paola Dal Cin
  • Valentina Nardi
  • Philip C Amrein
  • Meghan K Bergeron
  • Andrew M Brunner
  • Amir T Fathi
  • Julia E Foster
  • Jenna Moran
  • Timothy A Graubert
  • Hanno Hock
  • Chrisa Hunnewell
  • Matthew J Frigault
  • Steven McAfee
  • Gabriela S Hobbs
  • Leukemia.2020 Jul;10.1038/s41375-020-0983-x. doi: 10.1038/s41375-020-0983-x.Epub 2020-07-16.