イラン南部ホルムズガン州の妊婦における感染症の有病率と危険因子

Prevalence and Risk Factors of Infection among Pregnant Women in Hormozgan Province, South of Iran.

• Seyedeh Zahra Khademi
• Fatemeh Ghaffarifar
• Abdolhossein Dalimi
• Parivash Davoodian
• Amir Abdoli

抄録

背景:

トキソプラズマ症は胎児の流産や合併症を引き起こす可能性があります。特に妊娠初期に抗寄生虫薬による本疾患の診断と治療を行うことで、胎児感染とその合併症を予防することができる。本研究では、妊婦における感染症の判定、本疾患および先天性トキソプラズマ症の伝播の危険因子の評価を目的とした。

Background: Toxoplasmosis can cause miscarriage or complications in the fetus. Diagnosis and treatment of this disease by anti-parasitic drugs especially in early pregnancy can help to prevent fetal infection and its complications. This study aimed to determine infection in pregnant women, evaluate risk factors in the transmission of the disease and congenital toxoplasmosis.

方法:

全体として、イラン南部ホルムズガン州の気候の異なる5都市の妊婦360名の血清を2015～2016年にELISA法による感染症評価を行い、IgMとIgG陽性例をAvidity IgG ELISA法で再検査した。すべての症例について，気候，トキソプラズマ症の急性・慢性，妊娠・流産数，疫学的要因，食生活などの条件で評価した．

Methods: Overall, 360 sera of pregnant women from 5 cities in the Hormozgan Province in southern Iran with different climate were evaluated from 2015-2016 for infection by using ELISA method and positive cases of IgM and IgG were tested again using Avidity IgG ELISA. All cases were evaluated according to climate, acute and chronic of toxoplasmosis, number of pregnancy and abortion, epidemiological factors and food habits.

結果:

360検体中、IgG+IgM抗体が0.8％の被験者で陽性となり、27％の検体でIgG抗体陽性が認められた。年齢、採取場所、生肉および半調理肉の摂取量、猫との接触歴、中絶歴、子供の数、IgG陽性のパリティとの間には有意な関係が認められた。Avidity IgG ELISA検査では、Avidityが低値の13名、境界値の3名が報告された。

Results: Among 360 specimens IgG + IgM antibodies were found positive in 0. 8% subjects and also 27% of samples had IgG seropositivity. A significant relationship was observed between age, sampling place, consumption of raw and half cooked meat, history of contact with cats, abortion history, number of children, and parity with IgG positive. In Avidity IgG ELISA test, 13 people with low avidity, 3 people with borderline avidity were reported.

結論:

72.2％の人口は、これが人々への警告となり、予防と出生前ケアの教育と出産年齢の女性の定期的なスクリーニングを必要とする病気に対する抗体を持っていませんでした。

Conclusion: 72. 2% of the population had no antibody against the disease that this could be a warning to the people and requires education of preventive and prenatal care and routine screening of women at childbearing age.