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日本語AIでPubMedを検索

歯科医師情報サイトTOP / PubMed論文検索

日本語AIでPubMedを検索

PubMedの提供する医学論文データベースを日本語で検索できます。AI(Deep Learning)を活用した機械翻訳エンジンにより、精度高く日本語へ翻訳された論文をご参照いただけます。
対象期間    ～ 

2020年07月 みんなが読んでいる論文

ティモシー症候群の臨床成績と死亡様式。希少疾患の多施設国際研究

Clinical Outcomes and Modes of Death in Timothy Syndrome: A Multicenter International Study of a Rare Disorder.
  • Keith A Dufendach
  • Katherine Timothy
  • Michael J Ackerman
  • Benjamin Blevins
  • Andreas Pflaumer
  • Susan Etheridge
  • James Perry
  • Nico A Blom
  • Joel Temple
  • Devyani Chowdhury
  • Jonathan R Skinner
  • Christopher Johnsrude
  • Andras Bratincsak
  • J Martijn Bos
  • Maully Shah
  • JACC Clin Electrophysiol.2018 04;4(4):459-466. S2405-500X(17)30690-4. doi: 10.1016/j.jacep.2017.08.007.Epub 2017-11-06.

多施設緊急時（TIME）設定での持ち帰り用ナロキソンのプロトコル：フィージビリティスタディ

Protocol for Take-home naloxone In Multicentre Emergency (TIME) settings: feasibility study.
  • Matthew Jones
  • Fiona Bell
  • Jonathan Benger
  • Sarah Black
  • Penny Buykx
  • Simon Dixon
  • Tim Driscoll
  • Bridie Evans
  • Adrian Edwards
  • Gordon Fuller
  • Steve Goodacre
  • Rebecca Hoskins
  • Jane Hughes
  • Ann John
  • Jenna Jones
  • Chris Moore
  • Fiona Sampson
  • Alan Watkins
  • Helen Snooks
  • Pilot Feasibility Stud.2020;6:96. 626. doi: 10.1186/s40814-020-00626-w.Epub 2020-07-09.

コートジボワールとタンザニアにおける都市部の妊産婦顧客のHIV自己検査キットの使用意欲と支払い意欲。横断的研究

Willingness to use HIV self-test kits and willingness to pay among urban antenatal clients in Cote d'Ivoire and Tanzania: A cross-sectional study.
  • Kim Ashburn
  • Gretchen Antelman
  • Marc Kouadio N'Goran
  • Ola Jahanpour
  • Aida Yemaneberhan
  • Bernard N'Guessan Kouakou
  • Erin Kazemi
  • Malia Duffy
  • Pongathie Adama
  • Deborah Kajoka
  • Alexandra Coombs
  • Josef Tayag
  • David Sullivan
  • Alex Vrazo
  • Trop. Med. Int. Health.2020 Jul;doi: 10.1111/tmi.13456.Epub 2020-07-01.

著者訂正。カスパーゼ-9の内皮活性化は網膜静脈閉塞症における神経血管障害を促進する

Author Correction: Endothelial activation of caspase-9 promotes neurovascular injury in retinal vein occlusion.
  • Maria I Avrutsky
  • Crystal Colón Ortiz
  • Kendra V Johnson
  • Anna M Potenski
  • Claire W Chen
  • Jacqueline M Lawson
  • Alexandra J White
  • Stephanie K Yuen
  • Fatima N Morales
  • Elisa Canepa
  • Scott Snipas
  • Guy S Salvesen
  • Ying Y Jean
  • Carol M Troy
  • Nat Commun.2020 Jul;11(1):3502. 10.1038/s41467-020-17476-y. doi: 10.1038/s41467-020-17476-y.Epub 2020-07-09.

Sit4とPP2Aは、TorC1がアップレギュレーションされているときとダウンレギュレーションされているときに、窒素のカタボライトリプレッションに敏感なGln3を脱リン酸化している

Sit4 and PP2A Dephosphorylate Nitrogen Catabolite Repression-Sensitive Gln3 When TorC1 Is Up- as Well as Downregulated.
  • Jennifer J Tate
  • Elizabeth A Tolley
  • Terrance G Cooper
  • Genetics.2019 08;212(4):1205-1225. genetics.119.302371. doi: 10.1534/genetics.119.302371.Epub 2019-06-18.

カチオン/アニオン性ポリ電解質（PLL/PGA）でコーティングされたベシキュラーリン脂質ゲル（VPG）にシタラビンを負荷することで、持続的な放出と抗神経膠腫効果を得ることができます

Cationic/Anionic Polyelectrolyte (PLL/PGA) Coated Vesicular Phospholipid Gels (VPGs) Loaded with Cytarabine for Sustained Release and Anti-glioma Effects.
  • Na Qi
  • Yu Zhang
  • Xing Tang
  • Aimin Li
  • Drug Des Devel Ther.2020;14:1825-1836. 248362. doi: 10.2147/DDDT.S248362.Epub 2020-05-12.

重症COVID-19における脳MRI所見。レトロスペクティブ観察研究

Brain MRI Findings in Severe COVID-19: A Retrospective Observational Study.
  • Stéphane Kremer
  • François Lersy
  • Jérome de Sèze
  • Jean-Christophe Ferré
  • Adel Maamar
  • Béatrice Carsin-Nicol
  • Olivier Collange
  • Fabrice Bonneville
  • Gilles Adam
  • Guillaume Martin-Blondel
  • Marie Rafiq
  • Thomas Geeraerts
  • Louis Delamarre
  • Sylvie Grand
  • Alexandre Krainik
  • Sophie Caillard
  • Jean Marc Constans
  • Serge Metanbou
  • Adrien Heintz
  • Julie Helms
  • Maleka Schenck
  • Nicolas Lefèbvre
  • Claire Boutet
  • Xavier Fabre
  • Géraud Forestier
  • Isaure de Beaurepaire
  • Grégoire Bornet
  • Audrey Lacalm
  • Hélène Oesterlé
  • Federico Bolognini
  • Julien Messie
  • Ghazi Hmeydia
  • Joseph Benzakoun
  • Catherine Oppenheim
  • Blanche Bapst
  • Imen Megdiche
  • Marie-Cécile Henri-Feugeas
  • Antoine Khalil
  • Augustin Gaudemer
  • Lavinia Jager
  • Patrick Nesser
  • Yannick Talla Mba
  • Céline Hemmert
  • Philippe Feuerstein
  • Nathan Sebag
  • Sophie Carré
  • Manel Alleg
  • Claire Lecocq
  • Emmanuelle Schmitt
  • René Anxionnat
  • François Zhu
  • Pierre-Olivier Comby
  • Frédéric Ricolfi
  • Pierre Thouant
  • Hubert Desal
  • Grégoire Boulouis
  • Jérome Berge
  • Apolline Kazémi
  • Nadya Pyatigorskaya
  • Augustin Lecler
  • Suzana Saleme
  • Myriam Edjlali-Goujon
  • Basile Kerleroux
  • Pierre-Emmanuel Zorn
  • Muriel Mathieu
  • Seyyid Baloglu
  • François-Daniel Ardellier
  • Thibault Willaume
  • Jean Christophe Brisset
  • Clotilde Boulay
  • Véronique Mutschler
  • Yves Hansmann
  • Paul-Michel Mertes
  • Francis Schneider
  • Samira Fafi-Kremer
  • Mickael Ohana
  • Ferhat Meziani
  • Jean-Stéphane David
  • Nicolas Meyer
  • Mathieu Anheim
  • François Cotton
  • Radiology.2020 06;:202222. doi: 10.1148/radiol.2020202222.Epub 2020-06-16.

乳がんに対する女性の視点を理解することは、がん対策に不可欠である：タンザニアのムワンザにおける知識、リスク認識、ケア選択

Understanding women's perspectives on breast cancer is essential for cancer control: knowledge, risk awareness, and care-seeking in Mwanza, Tanzania.
  • Christina A Chao
  • Liuye Huang
  • Kala Visvanathan
  • Kisa Mwakatobe
  • Nestory Masalu
  • Anne F Rositch
  • BMC Public Health.2020 Jun;20(1):930. 10.1186/s12889-020-09010-y. doi: 10.1186/s12889-020-09010-y.Epub 2020-06-15.

カテリシジンはToll様受容体を介したシグナル伝達により、マウスの大腸炎を防御する

Cathelicidin signaling via the Toll-like receptor protects against colitis in mice.
  • Hon Wai Koon
  • David Q Shih
  • Jeremy Chen
  • Kyriaki Bakirtzi
  • Tressia C Hing
  • Ivy Law
  • Samantha Ho
  • Ryan Ichikawa
  • Dezheng Zhao
  • Hua Xu
  • Richard Gallo
  • Paul Dempsey
  • Genhong Cheng
  • Stephan R Targan
  • Charalabos Pothoulakis
  • Gastroenterology.2011 Nov;141(5):1852-63.e1-3. S0016-5085(11)00934-6. doi: 10.1053/j.gastro.2011.06.079.Epub 2011-07-14.

アリールケトン亜鉛結合に基づく選択的クラスI HDAC阻害剤は、HIV-1タンパク質のクリアランスを誘導する

Selective Class I HDAC Inhibitors Based on Aryl Ketone Zinc Binding Induce HIV-1 Protein for Clearance.
  • Jian Liu
  • Joseph Kelly
  • Wensheng Yu
  • Dane Clausen
  • Younong Yu
  • Hyunjin Kim
  • Joseph L Duffy
  • Christine C Chung
  • Robert W Myers
  • Steve Carroll
  • Daniel J Klein
  • James Fells
  • M Katharine Holloway
  • Jin Wu
  • Guoxin Wu
  • Bonnie J Howell
  • Richard J O Barnard
  • Joseph A Kozlowski
  • ACS Med Chem Lett.2020 Jul;11(7):1476-1483. doi: 10.1021/acsmedchemlett.0c00302.Epub 2020-06-22.

スペインの大規模病院の医療従事者におけるSARS-CoV-2に対する抗体の血清有病率

Seroprevalence of antibodies against SARS-CoV-2 among health care workers in a large Spanish reference hospital.
  • Alberto L Garcia-Basteiro
  • Gemma Moncunill
  • Marta Tortajada
  • Marta Vidal
  • Caterina Guinovart
  • Alfons Jiménez
  • Rebeca Santano
  • Sergi Sanz
  • Susana Méndez
  • Anna Llupià
  • Ruth Aguilar
  • Selena Alonso
  • Diana Barrios
  • Carlo Carolis
  • Pau Cisteró
  • Eugenia Chóliz
  • Angeline Cruz
  • Silvia Fochs
  • Chenjerai Jairoce
  • Jochen Hecht
  • Montserrat Lamoglia
  • Mikel J Martínez
  • Robert A Mitchell
  • Natalia Ortega
  • Nuria Pey
  • Laura Puyol
  • Marta Ribes
  • Neus Rosell
  • Patricia Sotomayor
  • Sara Torres
  • Sarah Williams
  • Sonia Barroso
  • Anna Vilella
  • José Muñoz
  • Antoni Trilla
  • Pilar Varela
  • Alfredo Mayor
  • Carlota Dobaño
  • Nat Commun.2020 07;11(1):3500. 10.1038/s41467-020-17318-x. doi: 10.1038/s41467-020-17318-x.Epub 2020-07-08.

LC─MS/MSを用いた受容体占有研究のための新規ホスホジエステラーゼ7Bトレーサーの迅速な同定

Rapid identification of a novel phosphodiesterase 7B tracer for receptor occupancy studies using LC─MS/MS.
  • Jie Chen
  • Guibao Gu
  • Mi Chen
  • Trevor Scott
  • Lindsay Heger
  • Douglas Zook
  • DeMichael Chung
  • Terence Keenan
  • Joel Renick
  • Vincent J Santora
  • Jeffrey Vivian
  • Kathe Stauber
  • James Guy Breitenbucher
  • Ali Tabatabaei
  • Neurochem. Int..2020 Jul;137:104735. S0197-0186(20)30126-1. doi: 10.1016/j.neuint.2020.104735.Epub 2020-04-01.

発達毒性のモデリングのために設計された腓骨周囲血管叢

Engineered Perineural Vascular Plexus for Modeling Developmental Toxicity.
  • Gaurav Kaushik
  • Kartik Gupta
  • Victoria Harms
  • Elizabeth Torr
  • Jonathan Evans
  • Hunter J Johnson
  • Cheryl Soref
  • Suehelay Acevedo-Acevedo
  • Jessica Antosiewicz-Bourget
  • Daniel Mamott
  • Peyton Uhl
  • Brian P Johnson
  • Sean P Palecek
  • David J Beebe
  • James A Thomson
  • William T Daly
  • William L Murphy
  • Adv Healthc Mater.2020 Jul;:e2000825. doi: 10.1002/adhm.202000825.Epub 2020-07-01.

巨大淡水エビ（）におけるインスリン様アンドロゲン腺ホルモン遺伝子とインスリン様アンドロゲン腺ホルモン結合タンパク質遺伝子の調節関係の解明

Insight into the Regulatory Relationships between the Insulin-Like Androgenic Gland Hormone Gene and the Insulin-Like Androgenic Gland Hormone-binding Protein Gene in Giant Freshwater Prawns ().
  • Guang Yang
  • Zhijie Lu
  • Zhendong Qin
  • Lijuan Zhao
  • Gan Pan
  • Haiyang Shen
  • Menglan Zhang
  • Rishen Liang
  • Li Lin
  • Kai Zhang
  • Int J Mol Sci.2020 Jun;21(12). E4207. doi: 10.3390/ijms21124207.Epub 2020-06-12.

電子中性Na輸送の障害とそれに伴うNHE3のダウンレギュレーションが下痢の発症に寄与していることを明らかにした

Impairment of electroneutral Na transport and associated downregulation of NHE3 contributes to the development of diarrhea following in vivo challenge with spp.
  • Cole B Enns
  • Brandon A Keith
  • Nitin Challa
  • John C S Harding
  • Matthew E Loewen
  • Am. J. Physiol. Gastrointest. Liver Physiol..2020 02;318(2):G288-G297. doi: 10.1152/ajpgi.00011.2019.Epub 2019-11-25.

フォトニック応用のためのユーロピウムイオンをドープしたゲルマネートガラスの発光研究

Luminescent Studies on Germanate Glasses Doped with Europium Ions for Photonic Applications.
  • Jacek Żmojda
  • Marcin Kochanowicz
  • Piotr Miluski
  • Piotr Golonko
  • Agata Baranowska
  • Tomasz Ragiń
  • Jan Dorosz
  • Marta Kuwik
  • Wojciech Pisarski
  • Joanna Pisarska
  • Renata Szal
  • Gabriela Mach
  • Bartosz Starzyk
  • Magdalena Leśniak
  • Maciej Sitarz
  • Dominik Dorosz
  • Materials (Basel).2020 Jun;13(12). E2817. doi: 10.3390/ma13122817.Epub 2020-06-23.

ナーシェントHDL（高密度リポタンパク質）ディスクは、HDL球体にコレステロールを運ぶ。コレステロールの流出に対するHDL粒子のリモデリングの効果

Nascent HDL (High-Density Lipoprotein) Discs Carry Cholesterol to HDL Spheres: Effects of HDL Particle Remodeling on Cholesterol Efflux.
  • Alexei V Navdaev
  • Lorenzo Sborgi
  • Samuel D Wright
  • Svetlana A Didichenko
  • Arterioscler. Thromb. Vasc. Biol..2020 05;40(5):1182-1194. doi: 10.1161/ATVBAHA.120.313906.Epub 2020-03-05.

フルファクターデザインを用いたバナナ疑似ステムパーティクルボードの特性に及ぼす樹脂含有量とプレス温度の影響

Effect of resin content and pressing temperature on banana pseudo-stem particle boards properties using full factorial design.
  • Ana D Barragàn-Lucas
  • Cristhian Llerena-Miranda
  • Maria Fernanda Quijano-Avilés
  • Iván A Chóez-Guaranda
  • Linda C Maldonado-Guerrero
  • Patricia I Manzano-Santana
  • An. Acad. Bras. Cienc..2019;91(4):e20180302. S0001-37652019000700903. doi: 10.1590/0001-3765201920180302.Epub 2019-12-02.

免疫チェックポイント阻害薬による治療を受けた再発・転移性頭頸部扁平上皮癌患者における高進行性疾患とその臨床的影響。韓国がん研究グループHN 18-12

Hyperprogressive disease and its clinical impact in patients with recurrent and/or metastatic head and neck squamous cell carcinoma treated with immune-checkpoint inhibitors: Korean cancer study group HN 18-12.
  • Jihyun Park
  • Sang Hoon Chun
  • Yun-Gyoo Lee
  • Hyun Chang
  • Keun-Wook Lee
  • Hye Ryun Kim
  • Seong Hoon Shin
  • Ho Jung An
  • Kyoung Eun Lee
  • In Gyu Hwang
  • Myung-Ju Ahn
  • Sung-Bae Kim
  • Bhumsuk Keam
  • J. Cancer Res. Clin. Oncol..2020 Jul;10.1007/s00432-020-03316-5. doi: 10.1007/s00432-020-03316-5.Epub 2020-07-15.

近赤外分光法で測定したベースラインの局所脳酸素飽和度に影響を与える高齢者と性別。プロスペクティブ研究のサブアナリシス

Advanced Age and Sex Influence Baseline Regional Cerebral Oxygen Saturation as Measured by Near-Infrared Spectroscopy: Subanalysis of a Prospective Study.
  • Cristina Bianca Robu
  • Alexandre Koninckx
  • Marie-Agnès Docquier
  • Irina Grosu
  • Laurent De Kerchove
  • Stefano Mastrobuoni
  • Mona Momeni
  • J. Cardiothorac. Vasc. Anesth..2020 Jun;S1053-0770(20)30566-8. doi: 10.1053/j.jvca.2020.06.025.Epub 2020-06-12.

農地を利用した岩石風化強化による大規模なCO2除去の可能性

Potential for large-scale CO removal via enhanced rock weathering with croplands.
  • David J Beerling
  • Euripides P Kantzas
  • Mark R Lomas
  • Peter Wade
  • Rafael M Eufrasio
  • Phil Renforth
  • Binoy Sarkar
  • M Grace Andrews
  • Rachael H James
  • Christopher R Pearce
  • Jean-Francois Mercure
  • Hector Pollitt
  • Philip B Holden
  • Neil R Edwards
  • Madhu Khanna
  • Lenny Koh
  • Shaun Quegan
  • Nick F Pidgeon
  • Ivan A Janssens
  • James Hansen
  • Steven A Banwart
  • Nature.2020 07;583(7815):242-248. 10.1038/s41586-020-2448-9. doi: 10.1038/s41586-020-2448-9.Epub 2020-07-08.

Fear of Missing Out（FoMO）とソーシャルメディアが日常生活や職場の生産性に与える影響。WhatsApp、Facebook、Instagram、Snapchat使用障害はその関連性を媒介するか？

Fear of Missing Out (FoMO) and social media's impact on daily-life and productivity at work: Do WhatsApp, Facebook, Instagram, and Snapchat Use Disorders mediate that association?
  • Dmitri Rozgonjuk
  • Cornelia Sindermann
  • Jon D Elhai
  • Christian Montag
  • Addict Behav.2020 May;110:106487. S0306-4603(20)30617-1. doi: 10.1016/j.addbeh.2020.106487.Epub 2020-05-27.

切除可能な非小細胞肺癌のリンパ節転移に対する円形腫瘍DNAに基づく術前非侵襲的予測モデルの開発と検証

Development and validation of a preoperative noninvasive predictive model based on circular tumor DNA for lymph node metastasis in resectable non-small cell lung cancer.
  • Rusi Zhang
  • Xuewen Zhang
  • Zirui Huang
  • Fang Wang
  • Yongbin Lin
  • Yingsheng Wen
  • Li Liu
  • Jinbo Li
  • Xinyi Liu
  • Wenzhuan Xie
  • Mengli Huang
  • Gongming Wang
  • Longjun Yang
  • Dechang Zhao
  • Xiangyang Yu
  • Kexing Xi
  • Weidong Wang
  • Ling Cai
  • Lanjun Zhang
  • Transl Lung Cancer Res.2020 Jun;9(3):722-730. tlcr-09-03-722. doi: 10.21037/tlcr-20-593.

CR3からLFA-1受容体へのリターゲティングは、アデニル酸シクラーゼ毒素のアデニル酸シクラーゼ酵素トランスロケーションセグメントを明らかにする

Retargeting from the CR3 to the LFA-1 receptor uncovers the adenylyl cyclase enzyme-translocating segment of adenylate cyclase toxin.
  • Jiri Masin
  • Adriana Osickova
  • David Jurnecka
  • Nela Klimova
  • Humaira Khaliq
  • Peter Sebo
  • Radim Osicka
  • J. Biol. Chem..2020 Jul;295(28):9349-9365. RA120.013630. doi: 10.1074/jbc.RA120.013630.Epub 2020-05-11.

種の分布モデリングにおける社会経済の利用。農村社会の特徴は、フクロウの発生予測を向上させる

The use of socio-economy in species distribution modelling: Features of rural societies improve predictions of barn owl occurrence.
  • Michał Żmihorski
  • Marek Kowalski
  • Jan Cichocki
  • Sławomir Rubacha
  • Dorota Kotowska
  • Dominik Krupiński
  • Zuzanna M Rosin
  • Martin Šálek
  • Tomas Pärt
  • Sci. Total Environ..2020 Jun;741:140407. S0048-9697(20)33929-2. doi: 10.1016/j.scitotenv.2020.140407.Epub 2020-06-20.

不妊症女性の膣マイクロバイオームの特徴と受精手術中のホルモン刺激との関連性

Characterization of the Vaginal Microbiome in Women with Infertility and Its Potential Correlation with Hormone Stimulation during Fertilization Surgery.
  • Changying Zhao
  • Zefeng Wei
  • Junjie Yang
  • Jiaming Zhang
  • Chunna Yu
  • Aijun Yang
  • Min Zhang
  • Lin Zhang
  • Ye Wang
  • Xiaofeng Mu
  • Xueyuan Heng
  • Huijun Yang
  • Zhongtao Gai
  • Xuenan Wang
  • Lei Zhang
  • mSystems.2020 Jul;5(4). e00450-20. doi: 10.1128/mSystems.00450-20.Epub 2020-07-14.

ヒトアポリポ蛋白質の大規模プロファイリングのためのハイスループット質量分析ベースのアッセイ

A high-throughput mass spectrometry-based assay for large-scale profiling of circulating human apolipoproteins.
  • Valentin Blanchard
  • Damien Garçon
  • Catherine Jaunet
  • Kevin Chemello
  • Stéphanie Billon-Crossouard
  • Audrey Aguesse
  • Aya Garfa
  • Gilles Famchon
  • Amada Torres
  • Cédric Le May
  • Matthieu Pichelin
  • Edith Bigot-Corbel
  • Gilles Lambert
  • Bertrand Cariou
  • Samy Hadjadj
  • Michel Krempf
  • Kalyane Bach-Ngohou
  • Mikaël Croyal
  • J. Lipid Res..2020 Jul;61(7):1128-1139. jlr.D120000835. doi: 10.1194/jlr.D120000835.Epub 2020-05-13.

細菌性エンドトキシンはガスデルミンD依存性ホスファチジルセリン暴露を介して凝固カスケードを活性化する．

Bacterial Endotoxin Activates the Coagulation Cascade through Gasdermin D-Dependent Phosphatidylserine Exposure.
  • Xinyu Yang
  • Xiaoye Cheng
  • Yiting Tang
  • Xianhui Qiu
  • Yupeng Wang
  • Haixia Kang
  • Jianfeng Wu
  • Zhongtai Wang
  • Yukun Liu
  • Fangping Chen
  • Xianzhong Xiao
  • Nigel Mackman
  • Timothy R Billiar
  • Jiahuai Han
  • Ben Lu
  • Immunity.2019 12;51(6):983-996.e6. S1074-7613(19)30463-7. doi: 10.1016/j.immuni.2019.11.005.Epub 2019-12-10.

タキシフォリンはニワトリ心筋細胞のチトクロームP450の恒常性を介してDEHP曝露によるアポトーシス障害を緩和する

Taxifolin alleviates apoptotic injury induced by DEHP exposure through cytochrome P450 homeostasis in chicken cardiomyocytes.
  • Yuan Zhang
  • Guangliang Shi
  • Jingzeng Cai
  • Jie Yang
  • Yingying Zheng
  • Dahai Yu
  • Qi Liu
  • Yafan Gong
  • Ziwei Zhang
  • Ecotoxicol. Environ. Saf..2019 Nov;183:109582. S0147-6513(19)30913-3. doi: 10.1016/j.ecoenv.2019.109582.Epub 2019-08-20.

侵略的外来種に対する科学者の警告

Scientists' warning on invasive alien species.
  • Petr Pyšek
  • Philip E Hulme
  • Dan Simberloff
  • Sven Bacher
  • Tim M Blackburn
  • James T Carlton
  • Wayne Dawson
  • Franz Essl
  • Llewellyn C Foxcroft
  • Piero Genovesi
  • Jonathan M Jeschke
  • Ingolf Kühn
  • Andrew M Liebhold
  • Nicholas E Mandrak
  • Laura A Meyerson
  • Aníbal Pauchard
  • Jan Pergl
  • Helen E Roy
  • Hanno Seebens
  • Mark van Kleunen
  • Montserrat Vilà
  • Michael J Wingfield
  • David M Richardson
  • Biol Rev Camb Philos Soc.2020 Jun;doi: 10.1111/brv.12627.Epub 2020-06-25.

二次元・三次元超音波を用いた大型エピグナス型奇形腫の出生前診断：病理所見との相関．

Prenatal diagnosis of a large epignathus teratoma using two-dimensional and three-dimensional ultrasound: correlation with pathological findings.
  • Maira Mariko Takagi
  • Luiz Claudio Silva Bussamra
  • E Araujo Júnior
  • Carolina Leite Drummond
  • Sandra Regina Silva Herbst
  • Luciano Marcondes Machado Nardozza
  • Antonio Fernandes Moron
  • José Mendes Aldrighi
  • Cleft Palate Craniofac. J..2014 May;51(3):350-3. doi: 10.1597/12-222.Epub 2013-02-11.

外科的に切除された非小細胞肺癌における予後を左右するラジオ免疫シグネチャーの同定に関するデータセット

Dataset on the identification of a prognostic radio-immune signature in surgically resected Non Small Cell Lung Cancer.
  • Giulia Mazzaschi
  • Gianluca Milanese
  • Paolo Pagano
  • Denise Madeddu
  • Letizia Gnetti
  • Francesca Trentini
  • Angela Falco
  • Caterina Frati
  • Bruno Lorusso
  • Costanza Lagrasta
  • Roberta Minari
  • Luca Ampollini
  • Mario Silva
  • Nicola Sverzellati
  • Federico Quaini
  • Giovanni Roti
  • Marcello Tiseo
  • Data Brief.2020 Aug;31:105781. S2352-3409(20)30675-2. doi: 10.1016/j.dib.2020.105781.Epub 2020-06-02.

多形性神経膠芽腫。質量分析イメージングにより明らかになった胸膜周囲組織およびIDH変異グリオーマとの代謝的差異

Glioblastoma multiforme: Metabolic differences to peritumoral tissue and IDH-mutated gliomas revealed by mass spectrometry imaging.
  • Judith M Kampa
  • Udo Kellner
  • Christian Marsching
  • Carina Ramallo Guevara
  • Ulrich J Knappe
  • Mikail Sahin
  • Marco Giampà
  • Karsten Niehaus
  • Hanna Bednarz
  • Neuropathology.2020 Jul;doi: 10.1111/neup.12671.Epub 2020-07-13.

コートジボワール西部での持続的なスキストソーマ・マンソニのホットスポットの特徴

Characteristics of persistent hotspots of Schistosoma mansoni in western Côte d'Ivoire.
  • Rufin K Assaré
  • Roméo N N'Tamon
  • Louise G Bellai
  • Judicaelle A Koffi
  • Tra-Bi I Mathieu
  • Mamadou Ouattara
  • Eveline Hürlimann
  • Jean T Coulibaly
  • Salia Diabaté
  • Eliézer K N'Goran
  • Jürg Utzinger
  • Parasit Vectors.2020 Jul;13(1):337. 10.1186/s13071-020-04188-x. doi: 10.1186/s13071-020-04188-x.Epub 2020-07-02.

4-メチルウンベリフェロンの抗増殖効果は、細胞内恒常性の破壊とPI3K/AKTおよびMAPKシグナル伝達の制御によって媒介されている

Antiproliferative Effect of 4-Methylumbelliferone in Epithelial Ovarian Cancer Cells Is Mediated by Disruption of Intracellular Homeostasis and Regulation of PI3K/AKT and MAPK Signaling.
  • Garam An
  • Sunwoo Park
  • Minkyoung Lee
  • Whasun Lim
  • Gwonhwa Song
  • Pharmaceutics.2020 Jul;12(7). E640. doi: 10.3390/pharmaceutics12070640.Epub 2020-07-07.

グリコーゲン合成酵素キナーゼ-3βは、12-O-テトラデカノイルフェノール-13-アセテート/イオノマイシン活性化ヒトCD4 Tリンパ球におけるサイトカイン産生を促進する

Glycogen Synthase Kinase-3β Facilitates Cytokine Production in 12-O-Tetradecanoylphorbol-13-Acetate/Ionomycin-Activated Human CD4 T Lymphocytes.
  • Cheng-Chieh Tsai
  • Chin-Kun Tsai
  • Po-Chun Tseng
  • Chiou-Feng Lin
  • Chia-Ling Chen
  • Cells.2020 Jun;9(6). E1424. doi: 10.3390/cells9061424.Epub 2020-06-08.

比較ゲノム解析により、臨床エリザベスキンキア髄膜敗血症における多様な病原性因子と抗菌薬耐性機構を明らかにした

Comparative genomic analyses reveal diverse virulence factors and antimicrobial resistance mechanisms in clinical Elizabethkingia meningoseptica strains.
  • Shicheng Chen
  • Marty Soehnlen
  • Jochen Blom
  • Nicolas Terrapon
  • Bernard Henrissat
  • Edward D Walker
  • PLoS ONE.2019;14(10):e0222648. PONE-D-19-17060. doi: 10.1371/journal.pone.0222648.Epub 2019-10-10.

パーキンソン病タンパク質LRRK2はGARP複合体と相互作用してゴルジ網への逆行輸送を促進する

The Parkinson's Disease Protein LRRK2 Interacts with the GARP Complex to Promote Retrograde Transport to the trans-Golgi Network.
  • Alexandra Beilina
  • Luis Bonet-Ponce
  • Ravindran Kumaran
  • Jennifer J Kordich
  • Morié Ishida
  • Adamantios Mamais
  • Alice Kaganovich
  • Sara Saez-Atienzar
  • David C Gershlick
  • Dorien A Roosen
  • Laura Pellegrini
  • Vlad Malkov
  • Matthew J Fell
  • Kirsten Harvey
  • Juan S Bonifacino
  • Darren J Moore
  • Mark R Cookson
  • Cell Rep.2020 May;31(5):107614. S2211-1247(20)30563-5. doi: 10.1016/j.celrep.2020.107614.

バレット食道および食道腺癌の機能的関連遺伝子座の同定：疾患関連組織からの発現定量形質遺伝子座データと遺伝学的関連データとのクロスリファレンス

Identification of loci of functional relevance to Barrett's esophagus and esophageal adenocarcinoma: Cross-referencing of expression quantitative trait loci data from disease-relevant tissues with genetic association data.
  • Julia Schröder
  • Vitalia Schüller
  • Andrea May
  • Christian Gerges
  • Mario Anders
  • Jessica Becker
  • Timo Hess
  • Nicole Kreuser
  • René Thieme
  • Kerstin U Ludwig
  • Tania Noder
  • Marino Venerito
  • Lothar Veits
  • Thomas Schmidt
  • Claudia Fuchs
  • Jakob R Izbicki
  • Arnulf H Hölscher
  • Dani Dakkak
  • Boris Jansen-Winkeln
  • Yusef Moulla
  • Orestis Lyros
  • Stefan Niebisch
  • Matthias Mehdorn
  • Hauke Lang
  • Dietmar Lorenz
  • Brigitte Schumacher
  • Rupert Mayershofer
  • Yogesh Vashist
  • Katja Ott
  • Michael Vieth
  • Josef Weismüller
  • Elisabeth Mangold
  • Markus M Nöthen
  • Susanne Moebus
  • Michael Knapp
  • Horst Neuhaus
  • Thomas Rösch
  • Christian Ell
  • Ines Gockel
  • Johannes Schumacher
  • Anne C Böhmer
  • PLoS ONE.2019;14(12):e0227072. PONE-D-19-25430. doi: 10.1371/journal.pone.0227072.Epub 2019-12-31.

BMP、FGF、RAシグナル伝達経路の複合的な調節によるヒト人工多能性幹細胞の産婦人科リンパ節様細胞への濃縮分化の研究

Enrichment differentiation of human induced pluripotent stem cells into sinoatrial node-like cells by combined modulation of BMP, FGF, and RA signaling pathways.
  • Feng Liu
  • Yibing Fang
  • Xiaojie Hou
  • Ying Yan
  • Haiying Xiao
  • Dongchuan Zuo
  • Jing Wen
  • Linli Wang
  • Zhichao Zhou
  • Xitong Dang
  • Rui Zhou
  • Bin Liao
  • Stem Cell Res Ther.2020 Jul;11(1):284. 10.1186/s13287-020-01794-5. doi: 10.1186/s13287-020-01794-5.Epub 2020-07-16.

カテプシンAはマウスの細胞外スーパーオキシドジスムターゼを分解することで左室リモデリングに寄与している

Cathepsin A contributes to left ventricular remodeling by degrading extracellular superoxide dismutase in mice.
  • Mathias Hohl
  • Manuel Mayr
  • Lisa Lang
  • Alexander G Nickel
  • Javier Barallobre Barreiro
  • Xiaoke Yin
  • Thimoteus Speer
  • Simina Ramona Selejan
  • Claudia Goettsch
  • Katharina Erb
  • Claudia Fecher-Trost
  • Jan-Christian Reil
  • Benedikt Linz
  • Sven Ruf
  • Thomas Hübschle
  • Christoph Maack
  • Michael Böhm
  • Thorsten Sadowski
  • Dominik Linz
  • J. Biol. Chem..2020 Jul;jbc.RA120.013488. doi: 10.1074/jbc.RA120.013488.Epub 2020-07-09.

甜菜嚢線虫のトランスクリプトーム配列から得られた新規ピコルナウイルス様ゲノムは、新属を代表するものである

A novel picornavirus-like genome from transcriptome sequencing of sugar beet cyst nematode represents a new putative genus.
  • Jingyu Lin
  • Rongjian Ye
  • Thanuja Thekke-Veetil
  • Margaret E Staton
  • Prakash R Arelli
  • Ernest C Bernard
  • Tarek Hewezi
  • Leslie L Domier
  • M R Hajimorad
  • J. Gen. Virol..2018 10;99(10):1418-1424. doi: 10.1099/jgv.0.001139.Epub 2018-08-29.

ブルガリア産イヌラ6種のカフェオレフィン酸、細胞毒性、抗酸化作用、アセチルコリンエステラーゼおよびチロシナーゼ酵素阻害活性

Caffeoylquinic Acids, Cytotoxic, Antioxidant, Acetylcholinesterase and Tyrosinase Enzyme Inhibitory Activities of Six Inula Species from Bulgaria.
  • Antoaneta Trendafilova
  • Victoria Ivanova
  • Miroslav Rangelov
  • Milka Todorova
  • Gulmira Ozek
  • Suleyman Yur
  • Temel Ozek
  • Ina Aneva
  • Ralitza Veleva
  • Veselina Moskova-Doumanova
  • Jordan Doumanov
  • Tanya Topouzova-Hristova
  • Chem. Biodivers..2020 Apr;17(4):e2000051. doi: 10.1002/cbdv.202000051.Epub 2020-03-18.

ガーナ人集団における抗レトロウイルス感染HIV患者における一塩基多型と脂質異常症との関連。ケースコントロール研究

Association of single nucleotide polymorphisms with dyslipidemia in antiretroviral exposed HIV patients in a Ghanaian population: A case-control study.
  • Christian Obirikorang
  • Emmanuel Acheampong
  • Lawrence Quaye
  • Joseph Yorke
  • Ernestine Kubi Amos-Abanyie
  • Priscilla Abena Akyaw
  • Enoch Odame Anto
  • Simon Bannison Bani
  • Evans Adu Asamoah
  • Emmanuella Nsenbah Batu
  • PLoS ONE.2020;15(1):e0227779. PONE-D-19-22071. doi: 10.1371/journal.pone.0227779.Epub 2020-01-13.

選択的で経口的に生物学的に利用可能な第XIa因子阻害剤の構造に基づく設計と前臨床特性の評価S1プロテアーゼファミリーの統合的アプローチの威力を実証

Structure-based design and pre-clinical characterization of selective and orally bioavailable Factor XIa inhibitors: Demonstrating the power of an integrated S1 protease family approach.
  • Edwige Lorthiois
  • James Roache
  • David Barnes-Seeman
  • Eva Altmann
  • Ulrich Hassiepen
  • Gordon Turner
  • Rohit Duvadie
  • Viktor Hornak
  • Rajeshri G Karki
  • Nikolaus Schiering
  • Wilhelm A Weihofen
  • Francesca Perruccio
  • Amy Calhoun
  • Tanzina Fazal
  • Darija Dedic
  • Corinne Durand
  • Solene Dussauge
  • Kamal Fettis
  • Fabien Tritsch
  • Celine Dentel
  • Adelaide Druet
  • Donglei Liu
  • Louise Kirman
  • Julie Lachal
  • Kenji Namoto
  • Douglas Bevan
  • Rose Mo
  • Gabriela Monnet
  • Lionel Muller
  • Richard Zessis
  • Xueming Huang
  • Loren Lindsley
  • Treeve Currie
  • Yu-Hsin Chiu
  • Cary Fridrich
  • Peter Delgado
  • Shuangxi Wang
  • Micah Hollis-Symynkywicz
  • Joerg Berghausen
  • Eric Williams
  • Hong Liu
  • Guiqing Liang
  • Hyungchul Kim
  • Peter Hoffmann
  • Andreas Hein
  • Paul Ramage
  • Allan D'Arcy
  • Stefanie Harlfinger
  • Martin Renatus
  • Simon Ruedisser
  • David Feldman
  • Jason Elliott
  • Richard C Sedrani
  • Jürgen Maibaum
  • Christopher M Adams
  • J. Med. Chem..2020 Jun;doi: 10.1021/acs.jmedchem.0c00279.Epub 2020-06-17.

ブラジルのマリアナ州（MG）の災害からの鉱滓は、キビ、トウモロコシ、ソルガムの初期発生に影響を与えるか？

Do tailings from the Mariana, MG (Brazil), disaster affect the initial development of millet, maize, and sorghum?
  • Gisele de Fátima Esteves
  • Leticia Aparecida Bressanin
  • Kamila Rezende Dázio de Souza
  • Adriano Bortolotti da Silva
  • José Ricardo Mantovani
  • Daniele Maria Marques
  • Paulo César Magalhães
  • Moacir Pasqual
  • Thiago Corrêa de Souza
  • Environ Sci Pollut Res Int.2020 Jul;10.1007/s11356-020-10013-w. doi: 10.1007/s11356-020-10013-w.Epub 2020-07-06.

地域個体群における夏季の卵の一時停止の発生率における微小生息地の変化．昆虫類の中でも特に夏場の卵の一時休止は、季節的な影響を受けていると考えられる

Microhabitat Variation in Egg Diapause Incidence in Summer Within a Local Population: An Adaptation to Decline in Host-Plant Suitability in Trigonotylus caelestialium (Hemiptera: Miridae).
  • Yoshinori Shintani
  • Keisuke Nagamine
  • Environ. Entomol..2020 Jul;nvaa063. doi: 10.1093/ee/nvaa063.Epub 2020-07-01.

HIV DNA上のヒストン負荷を探ることで、非統合型と統合型ウイルスゲノムの間のダイナミックなヌクレオソームの位置関係が明らかになった

Exploring histone loading on HIV DNA reveals a dynamic nucleosome positioning between unintegrated and integrated viral genome.
  • Shinichi Machida
  • David Depierre
  • Heng-Chang Chen
  • Suzie Thenin-Houssier
  • Gaël Petitjean
  • Cecile M Doyen
  • Motoki Takaku
  • Olivier Cuvier
  • Monsef Benkirane
  • Proc. Natl. Acad. Sci. U.S.A..2020 03;117(12):6822-6830. 1913754117. doi: 10.1073/pnas.1913754117.Epub 2020-03-11.

余暇の身体活動は、高心血管リスク者におけるHDL機能の改善と関連している：コホート研究

Leisure time physical activity is associated with improved HDL functionality in high cardiovascular risk individuals: a cohort study.
  • Álvaro Hernáez
  • Maria Trinidad Soria-Florido
  • Olga Castañer
  • Xavier Pintó
  • Ramón Estruch
  • Jordi Salas-Salvadó
  • Dolores Corella
  • Ángel Alonso-Gómez
  • Miguel Ángel Martínez-González
  • Helmut Schröder
  • Emilio Ros
  • Lluis Serra-Majem
  • Miquel Fiol
  • José Lapetra
  • Enrique Gomez-Gracia
  • Montserrat Fitó
  • Camille Lassale
  • Eur J Prev Cardiol.2020 Jun;:2047487320925625. doi: 10.1177/2047487320925625.Epub 2020-06-02.

再発・難治性慢性リンパ性白血病におけるイブルチニブの長期有効性。ポーランド成人白血病研究グループ観察研究の結果

Long-term Efficacy of Ibrutinib in Relapsed or Refractory Chronic Lymphocytic Leukemia: Results of the Polish Adult Leukemia Study Group Observational Study.
  • Bartosz Pula
  • Elzbieta Iskierka-Jazdzewska
  • Monika Dlugosz-Danecka
  • Agnieszka Szymczyk
  • Marek Hus
  • Agnieszka Szeremet
  • Joanna Drozd-Sokolowska
  • Anna Waszczuk-Gajda
  • Jan M Zaucha
  • Jadwiga Holojda
  • Weronika Piszczek
  • Pawel Steckiewicz
  • Malgorzata Wojciechowska
  • Michal Osowiecki
  • Wanda Knopinska-Posluszny
  • Marek Dudzinski
  • Daria Zawirska
  • Edyta Subocz
  • Janusz Halka
  • Andrzej Pluta
  • Ryszard Wichary
  • Beata Kumiega
  • Bozena K Budziszewska
  • Wojciech Jurczak
  • Ewa Lech-Maranda
  • Krzysztof Giannopoulos
  • Tadeusz Robak
  • Krzysztof Jamroziak
  • Anticancer Res..2020 Jul;40(7):4059-4066. 40/7/4059. doi: 10.21873/anticanres.14403.

酸化銅ナノ粒子への曝露は、酸化ストレスと小胞体（小胞体）ストレスによる毒性とアポトーシスを誘発することが明らかになった

Exposure to copper oxide nanoparticles triggers oxidative stress and endoplasmic reticulum (ER)-stress induced toxicology and apoptosis in male rat liver and BRL-3A cell.
  • Huanliang Liu
  • Wenqing Lai
  • Xiaohua Liu
  • Honglian Yang
  • Yanjun Fang
  • Lei Tian
  • Kang Li
  • Huipeng Nie
  • Wei Zhang
  • Yue Shi
  • Liping Bian
  • Susu Ding
  • Jun Yan
  • Bencheng Lin
  • Zhuge Xi
  • J. Hazard. Mater..2020 Jun;401:123349. S0304-3894(20)31338-8. doi: 10.1016/j.jhazmat.2020.123349.Epub 2020-06-30.

エジプト・ナイルデルタにおける小麦・トウモロコシ生産のウォーターフットプリントに対する気候変動の影響

The impact of climate changes on the water footprint of wheat and maize production in the Nile Delta, Egypt.
  • Ahmed Elbeltagi
  • Muhammad Rizwan Aslam
  • Anurag Malik
  • Behrouz Mehdinejadiani
  • Ankur Srivastava
  • Amandeep Singh Bhatia
  • Jinsong Deng
  • Sci. Total Environ..2020 Jul;743:140770. S0048-9697(20)34294-7. doi: 10.1016/j.scitotenv.2020.140770.Epub 2020-07-06.

アデノウイルス模倣ナノ粒子。アデノウイルスミメティックナノ粒子は、そのような細胞の同定のための普遍的なツールとしての連続的なリガンドと受容体の相互作用を強化したインビトロ/インビボの細胞識別

Adenovirus Mimetic Nanoparticles: Sequential Ligand-Receptor Interplay as a Universal Tool for Enhanced In Vitro/In Vivo Cell Identification.
  • Daniel Fleischmann
  • Sara Maslanka Figueroa
  • Sebastian Beck
  • Kathrin Abstiens
  • Ralph Witzgall
  • Frank Schweda
  • Philipp Tauber
  • Achim Michael Goepferich
  • ACS Appl Mater Interfaces.2020 Jul;doi: 10.1021/acsami.0c10057.Epub 2020-07-08.

全身性硬化症による間質性肺疾患患者におけるポマリドマイドの投与。A Phase II、多施設、無作為化、二重盲検、プラセボ対照、並行群間試験

Pomalidomide in Patients with Interstitial Lung Disease due to Systemic Sclerosis: A Phase II, Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel-group Study.
  • Vivien M Hsu
  • Christopher P Denton
  • Robyn T Domsic
  • Daniel E Furst
  • Maureen Rischmueller
  • Marina Stanislav
  • Virginia D Steen
  • Jörg H W Distler
  • Shimon Korish
  • Alyse Cooper
  • Suktae Choi
  • Peter H Schafer
  • Gerald Horan
  • Douglas R Hough
  • J. Rheumatol..2018 03;45(3):405-410. jrheum.161040. doi: 10.3899/jrheum.161040.Epub 2017-11-01.

プロテオミクス法を用いたフッ素誘導体化-液体クロマトグラフィー-タンデム質量分析法を用いたアリストロキチン酸腎症モデルマウスにおけるグリオキサラーゼ1に対するプレドニゾロンの効果

Effect of prednisolone on glyoxalase 1 in an inbred mouse model of aristolochic acid nephropathy using a proteomics method with fluorogenic derivatization-liquid chromatography-tandem mass spectrometry.
  • Shih-Ming Chen
  • Chia-En Lin
  • Hung-Hsiang Chen
  • Yu-Fan Cheng
  • Hui-Wen Cheng
  • Kazuhiro Imai
  • PLoS ONE.2020;15(1):e0227838. PONE-D-19-27780. doi: 10.1371/journal.pone.0227838.Epub 2020-01-22.

アジア人集団における動脈硬化性心血管病の二次予防のためのスタチン/エゼチミブの有効性。無作為化対照試験のシステマティックレビューとメタアナリシス

Efficacy of Statin/Ezetimibe for Secondary Prevention of Atherosclerotic Cardiovascular Disease in Asian Populations: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
  • Akshaya Srikanth Bhagavathula
  • Wafa Ali Aldhaleei
  • Nadya Obaid Al Matrooshi
  • Jamal Rahmani
  • Clin Drug Investig.2020 Jul;10.1007/s40261-020-00951-1. doi: 10.1007/s40261-020-00951-1.Epub 2020-07-15.

HLA遺伝子型と風邪薬誘発性Stevens-Johnson症候群/重度の眼合併症を伴う中毒性表皮壊死分解症：システマティックレビューとメタアナリシス

HLA genotypes and cold medicine-induced Stevens-Johnson syndrome/toxic epidermal necrolysis with severe ocular complications: a systematic review and meta-analysis.
  • Wimonchat Tangamornsuksan
  • Sirikan Chanprasert
  • Phenphechaya Nadee
  • Saowalak Rungruang
  • Natnaree Meesilsat
  • Mayumi Ueta
  • Manupat Lohitnavy
  • Sci Rep.2020 Jun;10(1):10589. 10.1038/s41598-020-67610-5. doi: 10.1038/s41598-020-67610-5.Epub 2020-06-29.

マウスのシステイン/シスチンおよびグルタチオン/グルタチオンジスルフィド血漿酸化還元電位カップルに対する性、年齢および食事の影響

Impact of sex, age and diet on the cysteine/cystine and glutathione/glutathione disulfide plasma redox couples in mice.
  • Walter H Watson
  • John C Greenwell
  • Yuxuan Zheng
  • Stephen Furmanek
  • Edilson Torres-Gonzalez
  • Jeffrey D Ritzenthaler
  • Jesse Roman
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ベトナムのハイフォンでは、HIVコントロールプログラムによって薬物を注射した人のHIV発症率は減少するが、HCVの発症率は減少しない

HIV control programs reduce HIV incidence but not HCV incidence among people who inject drugs in HaiPhong, Vietnam.
  • Jean-Pierre Molès
  • Roselyne Vallo
  • Pham Minh Khue
  • Duong Thi Huong
  • Khuat Thi Hai Oanh
  • Nguyen Thi Thoa
  • Hoang Thi Giang
  • Nham Thi Tuyet Thanh
  • Vu Hai Vinh
  • Tuyet Anh Bui Thi
  • Marianne Peries
  • Kamyar Arasteh
  • Catherine Quillet
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茶植物におけるガロイル化カテキンの生合成に関与する酵素の進化と特徴付けのためのセリンカルボキシペプチダーゼ様アシルトランスフェラーゼ遺伝子ファミリーのゲノムワイド解析()

Genome-Wide Analysis of Serine Carboxypeptidase-Like Acyltransferase Gene Family for Evolution and Characterization of Enzymes Involved in the Biosynthesis of Galloylated Catechins in the Tea Plant ().
  • Muhammad Zulfiqar Ahmad
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  • Guangbiao She
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  • Xiao Chun Wan
  • Jian Zhao
  • Front Plant Sci.2020;11:848. doi: 10.3389/fpls.2020.00848.Epub 2020-06-25.

軽度の認知機能障害を有するパーキンソン病における線条体ドーパミン神経細胞の完全性と認知機能障害および大脳皮質代謝との関連

Association of striatal dopaminergic neuronal integrity with cognitive dysfunction and cerebral cortical metabolism in Parkinson's disease with mild cognitive impairment.
  • Heeyoung Kim
  • Minyoung Oh
  • Jungsu S Oh
  • Hyojeong Moon
  • Sun Ju Chung
  • Chong Sik Lee
  • Jae Seung Kim
  • Nucl Med Commun.2019 Dec;40(12):1216-1223. doi: 10.1097/MNM.0000000000001098.

再発性/転移性頭頸部扁平上皮がんにおけるニボルマブ後のサルベージ化学療法の治療成績の予測におけるプログラム死リガンド1の役割

Role of programmed death-ligand 1 in predicting the treatment outcome of salvage chemotherapy after nivolumab in recurrent/metastatic head and neck squamous cell carcinoma.
  • Yushi Ueki
  • Takeshi Takahashi
  • Hisayuki Ota
  • Ryusuke Shodo
  • Keisuke Yamazaki
  • Arata Horii
  • Head Neck.2020 Jul;doi: 10.1002/hed.26374.Epub 2020-07-16.

低レベルレーザー光治療は骨格筋修復におけるI型およびIII型コラーゲンのリモデリングに影響を与える

Phototherapy with low-level laser affects the remodeling of types I and III collagen in skeletal muscle repair.
  • Thais Oricchio Fedri de Souza
  • Dayane Aparecida Mesquita
  • Raquel Agnelli Mesquita Ferrari
  • Décio Dos Santos Pinto
  • Luciana Correa
  • Sandra Kalil Bussadori
  • Kristianne Porta Santos Fernandes
  • Manoela Domingues Martins
  • Lasers Med Sci.2011 Nov;26(6):803-14. doi: 10.1007/s10103-011-0951-9.Epub 2011-07-15.

SMPD1遺伝子にp.L43_A44delLAのヘテロ接合変異を持つニーマン・ピック病B型患者からの誘導多能性幹細胞株（TRNDi004-I）の作製

Generation of an induced pluripotent stem cell line (TRNDi004-I) from a Niemann-Pick disease type B patient carrying a heterozygous mutation of p.L43_A44delLA in the SMPD1 gene.
  • Amanda Baskfield
  • Rong Li
  • Jeanette Beers
  • Jizhong Zou
  • Chengyu Liu
  • Wei Zheng
  • Stem Cell Res.2019 05;37:101436. S1873-5061(19)30066-2. doi: 10.1016/j.scr.2019.101436.Epub 2019-04-12.

クラウドベースのフリーエネルギー計算、合成を意識した列挙、目標指向の生成的機械学習を組み合わせて、大規模化学物質の迅速な探索と最適化を実現します

Combining Cloud-Based Free-Energy Calculations, Synthetically Aware Enumerations, and Goal-Directed Generative Machine Learning for Rapid Large-Scale Chemical Exploration and Optimization.
  • Phani Ghanakota
  • Pieter H Bos
  • Kyle D Konze
  • Joshua Staker
  • Gabriel Marques
  • Kyle Marshall
  • Karl Leswing
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  • J Chem Inf Model.2020 Jun;doi: 10.1021/acs.jcim.0c00120.Epub 2020-06-19.

欧州南東部諸国におけるアフリカ豚熱のリスク評価

Risk assessment of African swine fever in the south-eastern countries of Europe.
  • Søren Saxmose Nielsen
  • Julio Alvarez
  • Dominique Bicout
  • Paolo Calistri
  • Klaus Depner
  • Julian Ashley Drewe
  • Bruno Garin-Bastuji
  • Jose Luis Gonzales Rojas
  • Virginie Michel
  • Miguel Angel Miranda
  • Helen Roberts
  • Liisa Sihvonen
  • Hans Spoolder
  • Karl Ståhl
  • Arvo Viltrop
  • Christoph Winckler
  • Anette Boklund
  • Anette Bøtner
  • Jose Luis Gonzales Rojas
  • Simon J More
  • Hans-Hermann Thulke
  • Sotiria-Eleni Antoniou
  • José Cortinas Abrahantes
  • Sofie Dhollander
  • Andrey Gogin
  • Alexandra Papanikolaou
  • Laura C Gonzalez Villeta
  • Christian Gortázar Schmidt
  • EFSA J.2019 Nov;17(11):e05861. EFS25861. doi: 10.2903/j.efsa.2019.5861.Epub 2019-11-05.

PDGFRA変異GISTの遺伝子発現プロファイリングにより、D842Vエクソン18変異の特異的なフィンガープリントとしての免疫シグネチャーが明らかになった

Gene Expression Profiling of PDGFRA Mutant GIST Reveals Immune Signatures as a Specific Fingerprint of D842V Exon 18 Mutation.
  • Valentina Indio
  • Gloria Ravegnini
  • Annalisa Astolfi
  • Milena Urbini
  • Maristella Saponara
  • Antonio De Leo
  • Elisa Gruppioni
  • Giuseppe Tarantino
  • Sabrina Angelini
  • Andrea Pession
  • Maria Abbondanza Pantaleo
  • Margherita Nannini
  • Front Immunol.2020;11:851. doi: 10.3389/fimmu.2020.00851.Epub 2020-06-02.

心血管イベントを減少させるための米国食品医薬品局（FDA）の適応拡大に伴う抗高血糖薬の使用。学術医療センター内での処方パターン

Antihyperglycemic Therapies with Expansions of US Food and Drug Administration Indications to Reduce Cardiovascular Events: Prescribing Patterns within an Academic Medical Center.
  • Arsalan Hamid
  • Muthiah Vaduganathan
  • Adebamike Oshunbade
  • Krishna K Ayyalasomayajula
  • Andreas P Kalogeropoulos
  • Lillian F Lien
  • Tariq Shafi
  • Michael Hall
  • Javed Butler
  • J. Cardiovasc. Pharmacol..2020 Jun;doi: 10.1097/FJC.0000000000000864.Epub 2020-06-17.

重症再生不良性貧血に対してシクロスポリンとレバミソールを交互に併用した新規免疫抑制療法の長期追跡調査を行った

Long-term follow-up of a novel immunosuppressive strategy of cyclosporine alternatively combined with levamisole for severe aplastic anemia.
  • Jiali Huo
  • Xingxin Li
  • Yingqi Shao
  • Xiang Ren
  • Meili Ge
  • Yahong You
  • Jinbo Huang
  • Jing Zhang
  • Min Wang
  • Neng Nie
  • Peng Jin
  • Yizhou Zheng
  • Ann. Hematol..2020 Aug;99(8):1727-1734. 10.1007/s00277-020-04153-9. doi: 10.1007/s00277-020-04153-9.Epub 2020-06-29.

1997年から2017年までのサハラ以南のアフリカにおけるマラリア対策のための屋内残留噴霧：調整済みレトロスペクティブ分析

Indoor residual spraying for malaria control in sub-Saharan Africa 1997 to 2017: an adjusted retrospective analysis.
  • Julie-Anne A Tangena
  • Chantal M J Hendriks
  • Maria Devine
  • Meghan Tammaro
  • Anna E Trett
  • Ignatius Williams
  • Adilson José DePina
  • Achamylesh Sisay
  • Ramandimbiarijaona Herizo
  • Hmooda Toto Kafy
  • Elizabeth Chizema
  • Allan Were
  • Jennifer Rozier
  • Michael Coleman
  • Catherine L Moyes
  • Malar. J..2020 Apr;19(1):150. 10.1186/s12936-020-03216-6. doi: 10.1186/s12936-020-03216-6.Epub 2020-04-10.

1990年から2017年までのBRICS諸国における身体リハビリテーションのニーズ．世界疾病負担調査のデータを用いた国をまたいだ分析

Physical Rehabilitation Needs in the BRICS Nations from 1990 to 2017: Cross-National Analyses Using Data from the Global Burden of Disease Study.
  • Tiago S Jesus
  • Michel D Landry
  • Helen Hoenig
  • Yi Zeng
  • Sureshkumar Kamalakannan
  • Raquel R Britto
  • Nana Pogosova
  • Olga Sokolova
  • Karen Grimmer
  • Quinette A Louw
  • Int J Environ Res Public Health.2020 Jun;17(11). E4139. doi: 10.3390/ijerph17114139.Epub 2020-06-10.

子宮筋腫に対する超音波ガイド下高強度集束超音波（USgHIFU）アブレーションと腹腔鏡下子宮筋腫切除術の妊娠転帰の比較：比較研究

A comparison of the pregnancy outcomes between ultrasound-guided high-intensity focused ultrasound ablation and laparoscopic myomectomy for uterine fibroids: a comparative study.
  • Guangping Wu
  • Rong Li
  • Min He
  • Yuanfang Pu
  • Jishu Wang
  • Jinyun Chen
  • Hongbo Qi
  • Int J Hyperthermia.2020;37(1):617-623. doi: 10.1080/02656736.2020.1774081.

頭頸部扁平上皮癌の再発性または転移性頭頸部扁平上皮癌を対象としたTalimogene LaherparepvecとPembrolizumabの併用療法（MASTERKEY-232）。多施設共同第1b相試験

Talimogene Laherparepvec and Pembrolizumab in Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck (MASTERKEY-232): A Multicenter, Phase 1b Study.
  • Kevin J Harrington
  • Anthony Kong
  • Nicolas Mach
  • Jason Chesney
  • Beatriz Castelo Fernandez
  • Danny Rischin
  • Ezra E W Cohen
  • Hoi-Shen Radcliffe
  • Burak Gumuscu
  • Jonathan Cheng
  • Wendy Snyder
  • Lillian L Siu
  • Clin. Cancer Res..2020 Jul;clincanres.1170.2020. doi: 10.1158/1078-0432.CCR-20-1170.Epub 2020-07-15.

爪真菌症の治療におけるフラクショナル2940nm Er:YAGレーザーと5%アモロルフィンラッカーの併用療法と5%アモロルフィンラッカー単剤療法の比較：無作為化比較試験

Comparison of a fractional 2940-nm Er:YAG laser and 5% amorolfine lacquer combination therapy versus a 5% amorolfine lacquer monotherapy for the treatment of onychomycosis: a randomized controlled trial.
  • Jing Zhang
  • Yunqing Zhang
  • Jinglin Qin
  • Sha Lu
  • Wenying Cai
  • Jiahao Li
  • Huaiqiu Huang
  • Sulian Yang
  • Liyan Xi
  • Lasers Med Sci.2020 Jun;10.1007/s10103-020-03054-7. doi: 10.1007/s10103-020-03054-7.Epub 2020-06-17.

喘息患者および健康な個体における家畜農場からの粒子状物質に対する生体外自然応答

Ex vivo innate responses to particulate matter from livestock farms in asthma patients and healthy individuals.
  • Linsey E S de Groot
  • Dingyu Liu
  • Barbara S Dierdorp
  • Niki Fens
  • Marianne A van de Pol
  • Peter J Sterk
  • Wim Kulik
  • Miriam E Gerlofs-Nijland
  • Flemming R Cassee
  • Elena Pinelli
  • René Lutter
  • Environ Health.2020 Jul;19(1):78. 10.1186/s12940-020-00632-8. doi: 10.1186/s12940-020-00632-8.Epub 2020-07-03.

マダガスカルの白亜紀哺乳類の骨格は長期的な不規則性を反映している

Skeleton of a Cretaceous mammal from Madagascar reflects long-term insularity.
  • David W Krause
  • Simone Hoffmann
  • Yaoming Hu
  • John R Wible
  • Guillermo W Rougier
  • E Christopher Kirk
  • Joseph R Groenke
  • Raymond R Rogers
  • James B Rossie
  • Julia A Schultz
  • Alistair R Evans
  • Wighart von Koenigswald
  • Lydia J Rahantarisoa
  • Nature.2020 05;581(7809):421-427. 10.1038/s41586-020-2234-8. doi: 10.1038/s41586-020-2234-8.Epub 2020-04-29.

イネ科コイの遺伝子型II型イネ科レオウイルス感染後の臨床症状，ウイルス分布，抗ウイルス免疫関連遺伝子のmRNA発現に関する研究

Studies on the clinical symptoms, virus distribution, and mRNA expression of several antiviral immunity-related genes in grass carp after infection with genotype II grass carp reovirus.
  • Minglin Wu
  • Haiyang Li
  • Xiaowu Chen
  • Yangyang Jiang
  • Wei Jiang
  • Arch. Virol..2020 Jul;165(7):1599-1609. 10.1007/s00705-020-04654-y. doi: 10.1007/s00705-020-04654-y.Epub 2020-05-12.

早漏、その診断とフォルタシンスプレーによる局所治療に対する認識、期待、嗜好、態度。専門家パネルディスカッションの結果

Perceptions, Expectations, Preferences, and Attitudes Toward Premature Ejaculation, Its Diagnosis and Topical Treatment with Fortacin™ Spray: Results from an Expert Panel Discussion.
  • Ferdinando Fusco
  • Massimiliano Creta
  • Francesco Mangiapia
  • Lorenzo Cirigliano
  • Francesco Trama
  • Savio Domenico Pandolfo
  • Ciro Imbimbo
  • Nicola Longo
  • Vincenzo Mirone
  • Res Rep Urol.2020;12:211-216. 250301. doi: 10.2147/RRU.S250301.Epub 2020-07-02.

制御されたドキソルビシン送達のための磁気共鳴活性化可能な熱感受性リポソーム

Magnetic resonance activatable thermosensitive liposomes for controlled doxorubicin delivery.
  • Mohamad Alawak
  • Gihan Mahmoud
  • Alice Abu Dayyih
  • Lili Duse
  • Shashank Reddy Pinnapireddy
  • Konrad Engelhardt
  • Ibrahim Awak
  • Christian Wölk
  • Alexander M König
  • Jana Brüßler
  • Udo Bakowsky
  • Mater Sci Eng C Mater Biol Appl.2020 Oct;115:111116. S0928-4931(20)30616-0. doi: 10.1016/j.msec.2020.111116.Epub 2020-05-25.

オーストラリア、ビクトリア州の公立病院における難民背景を持つ女性のための妊産婦ケアへのアクセスを改善するためのシステム改革の評価。中断された時系列のデザイン

Evaluation of systems reform in public hospitals, Victoria, Australia, to improve access to antenatal care for women of refugee background: An interrupted time series design.
  • Jane Yelland
  • Fiona Mensah
  • Elisha Riggs
  • Ellie McDonald
  • Josef Szwarc
  • Wendy Dawson
  • Dannielle Vanpraag
  • Sue Casey
  • Christine East
  • Mary Anne Biro
  • Glyn Teale
  • Sue Willey
  • Stephanie J Brown
  • PLoS Med..2020 Jul;17(7):e1003089. PMEDICINE-D-19-03494. doi: 10.1371/journal.pmed.1003089.Epub 2020-07-10.

脳性麻痺患者の下肢痙縮の治療におけるボツリヌス毒素A型注射と比較した放射状体外衝撃波治療の有効性。無作為化対照クロスオーバー試験

Efficacy of radial extracorporeal shock wave therapy compared with botulinum toxin type A injection in treatment of lower extremity spasticity in subjects with cerebral palsy: A randomized, controlled, cross-over study.
  • Xavier Vidal
  • Joan Martí-Fàbregas
  • Olga Canet
  • Marta Roqué
  • Antoni Morral
  • Miriam Tur
  • Christoph Schmitz
  • Mercè Sitjà-Rabert
  • J Rehabil Med.2020 Jun;52(6):jrm00076. doi: 10.2340/16501977-2703.Epub 2020-06-30.

脳内浸透型のPQR620 mTORとPQR530 PI3K/mTOR阻害剤はHDの細胞モデルにおけるハンチントン病レベルを低下させる

Brain-penetrant PQR620 mTOR and PQR530 PI3K/mTOR inhibitor reduce huntingtin levels in cell models of HD.
  • Elisabeth Singer
  • Carolin Walter
  • Doriano Fabbro
  • Denise Rageot
  • Florent Beaufils
  • Matthias P Wymann
  • Nadine Rischert
  • Olaf Riess
  • Petra Hillmann
  • Huu Phuc Nguyen
  • Neuropharmacology.2020 01;162:107812. S0028-3908(19)30379-X. doi: 10.1016/j.neuropharm.2019.107812.Epub 2019-10-14.

ブラジルにおける非妊娠女性を対象とした活動性梅毒に対するセフィキシムの臨床効果を評価する第 II 相試験（CeBra）

Phase II trial evaluating the clinical efficacy of cefixime for treatment of active syphilis in non-pregnant women in Brazil (CeBra).
  • Melanie M Taylor
  • Edna Oliveira Kara
  • Maria Alix Leite Araujo
  • Mariangela Freitas Silveira
  • Angelica Espinosa Miranda
  • Ivo Castelo Branco Coelho
  • Maria Luiza Bazzo
  • Gerson Fernando Mendes Pereira
  • Silvana Pereira Giozza
  • Ximena Pamela Díaz Bermudez
  • Maeve B Mello
  • Ndema Habib
  • My Huong Nguyen
  • Soe Soe Thwin
  • Nathalie Broutet
  • BMC Infect. Dis..2020 Jun;20(1):405. 10.1186/s12879-020-04980-1. doi: 10.1186/s12879-020-04980-1.Epub 2020-06-10.

T2および拡散強調MRIを用いた子宮頸癌における体積の描出。オブザーバー間の体積の一致

Volume Delineation in Cervical Cancer With T2 and Diffusion-weighted MRI: Agreement on Volumes Between Observers.
  • Consuelo Rosa
  • Andrea Delli Pizzi
  • Antonietta Augurio
  • Luciana Caravatta
  • Monica DI Tommaso
  • Erica Mincuzzi
  • Sebastiano Cinalli
  • Raffaella Basilico
  • Annamaria Porreca
  • Marta DI Nicola
  • Domenico Genovesi
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再建手術を受けている乳がん患者に対するマッサージとマッサージプラス鍼治療との比較

Massage Compared with Massage Plus Acupuncture for Breast Cancer Patients Undergoing Reconstructive Surgery.
  • Christina A Dilaveri
  • Ivana T Croghan
  • Molly J Mallory
  • Liza J Dion
  • Karen M Fischer
  • Darrell R Schroeder
  • Jorys Martinez-Jorge
  • Minh-Doan T Nguyen
  • Shawn C Fokken
  • Brent A Bauer
  • Dietlind L Wahner-Roedler
  • J Altern Complement Med.2020 Jul;26(7):602-609. doi: 10.1089/acm.2019.0479.

アルツハイマー病における神経炎症メカニズムの精密医療への道

A Path Toward Precision Medicine for Neuroinflammatory Mechanisms in Alzheimer's Disease.
  • Harald Hampel
  • Filippo Caraci
  • A Claudio Cuello
  • Giuseppe Caruso
  • Robert Nisticò
  • Massimo Corbo
  • Filippo Baldacci
  • Nicola Toschi
  • Francesco Garaci
  • Patrizia A Chiesa
  • Steven R Verdooner
  • Leyla Akman-Anderson
  • Félix Hernández
  • Jesús Ávila
  • Enzo Emanuele
  • Pedro L Valenzuela
  • Alejandro Lucía
  • Mark Watling
  • Bruno P Imbimbo
  • Andrea Vergallo
  • Simone Lista
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帯状疱疹と認知症との関連性と抗ウイルス療法の認知症リスクへの効果：集団ベースのコホート研究

Association of herpes zoster with dementia and effect of antiviral therapy on dementia: a population-based cohort study.
  • Seongman Bae
  • Sung-Cheol Yun
  • Min-Chul Kim
  • Woon Yoon
  • Joon Seo Lim
  • Sang-Oh Lee
  • Sang-Ho Choi
  • Yang Soo Kim
  • Jun Hee Woo
  • Seong Yoon Kim
  • Sung-Han Kim
  • Eur Arch Psychiatry Clin Neurosci.2020 Jul;10.1007/s00406-020-01157-4. doi: 10.1007/s00406-020-01157-4.Epub 2020-07-01.

再治療の長期フォローアップとアウトカム転移性去勢抵抗性前立腺癌におけるルテチウム-177（Lu）PSMA-617療法の拡張50患者単施設第II相前向き試験における再治療の長期フォローアップとアウトカム

Re: Long Term Follow-Up and Outcomes of Re-Treatment in an Expanded 50 Patient Single-Center Phase II Prospective Trial of Lutetium-177 (Lu) PSMA-617 Theranostics in Metastatic Castrate-Resistant Prostate Cancer.
  • Samir S Taneja
  • J. Urol..2020 05;203(5):882. doi: 10.1097/JU.0000000000000779.01.Epub 2020-02-13.

ホルモン受容体陽性/HER2陰性の早期乳癌患者における、免疫組織化学的に定義された腔状サブタイプに応じた用量密度の高い補助化学療法の効果：GIM2試験の探索的解析

Effect of dose-dense adjuvant chemotherapy in hormone receptor positive/HER2-negative early breast cancer patients according to immunohistochemically defined luminal subtype: an exploratory analysis of the GIM2 trial.
  • Benedetta Conte
  • Marco Bruzzone
  • Matteo Lambertini
  • Francesca Poggio
  • Claudia Bighin
  • Eva Blondeaux
  • Michelino De Laurentiis
  • Enrichetta Valle
  • Francesco Cognetti
  • Cecilia Nisticò
  • Sabino De Placido
  • Ornella Garrone
  • Teresa Gamucci
  • Filippo Montemurro
  • Fabio Puglisi
  • Barbara Cardinali
  • Piero Fregatti
  • Loredana Miglietta
  • Francesco Boccardo
  • Marcello Ceppi
  • Lucia Del Mastro
  • Eur. J. Cancer.2020 Jul;136:43-51. S0959-8049(20)30273-2. doi: 10.1016/j.ejca.2020.05.007.Epub 2020-07-04.

高齢マウスにアジュバント組換えインフルエンザ核タンパク質をワクチン接種すると，防御免疫が増強される．

Vaccination of aged mice with adjuvanted recombinant influenza nucleoprotein enhances protective immunity.
  • Tres Cookenham
  • Kathleen G Lanzer
  • Emily Gage
  • Erica C Lorenzo
  • Darrick Carter
  • Rhea N Coler
  • Susan L Baldwin
  • Laura Haynes
  • William W Reiley
  • Marcia A Blackman
  • Vaccine.2020 Jul;38(33):5256-5267. S0264-410X(20)30752-0. doi: 10.1016/j.vaccine.2020.05.085.Epub 2020-06-12.

小児小脳悪性腫瘍の治療を目的とした抗がん剤HSV G207のヒト初の第1相免疫療法臨床試験のデザインと根拠

Design and Rationale for First-In-Human Phase 1 Immunovirotherapy Clinical Trial of Oncolytic HSV G207 to Treat Malignant Pediatric Cerebellar Brain Tumors.
  • Joshua D Bernstock
  • Asim Bag
  • John Fiveash
  • Kara Kachurak
  • Galal Elsayed
  • Gustavo Chagoya
  • Florian Gessler
  • Pablo A Valdes
  • Avi Madan-Swain
  • Richard Whitley
  • James Markert
  • Yancey Gillespie
  • James M Johnston
  • Gregory K Friedman
  • Hum. Gene Ther..2020 Jul;doi: 10.1089/hum.2020.101.Epub 2020-07-12.

マンソン病の免疫調節分子Sm16/SPO-1/SmSLPは、トレマトード特異的な蠕虫防御分子（HDM）の一種です

Schistosoma mansoni immunomodulatory molecule Sm16/SPO-1/SmSLP is a member of the trematode-specific helminth defence molecules (HDMs).
  • Jenna Shiels
  • Krystyna Cwiklinski
  • Raquel Alvarado
  • Karine Thivierge
  • Sophie Cotton
  • Bibiana Gonzales Santana
  • Joyce To
  • Sheila Donnelly
  • Clifford C Taggart
  • Sinead Weldon
  • John P Dalton
  • PLoS Negl Trop Dis.2020 Jul;14(7):e0008470. PNTD-D-20-00627. doi: 10.1371/journal.pntd.0008470.Epub 2020-07-09.

DL-3-n-ブチルフタル酸は，大脳動脈硬化性狭窄症患者における脳血流低下を改善する：単施設，無作為化，二重盲検，プラセボ対照試験

DL-3-n-butylphthalide improves cerebral hypoperfusion in patients with large cerebral atherosclerotic stenosis: a single-center, randomized, double-blind, placebo-controlled study.
  • Dawei Chen
  • Yanwei Yin
  • Jin Shi
  • Fen Yang
  • Kehua Wang
  • Faguo Zhao
  • Wenping Li
  • Bin Li
  • BMC Neurol.2020 May;20(1):212. 10.1186/s12883-020-01801-5. doi: 10.1186/s12883-020-01801-5.Epub 2020-05-26.

思春期の若者におけるうつ病とモバイルテクノロジーやソーシャルメディアの利用との関係：アンブレラレビュー

Relationship between depression and the use of mobile technologies and social media among adolescents: an umbrella review.
  • Jorge Arias-de la Torre
  • Elisa Puigdomenech
  • Xavier Garcia
  • Jose M Valderas
  • Francisco Jose Eiroa-Orosa
  • Tania Fernandez-Villa
  • Antonio J Molina
  • Vicente Martin
  • Antoni Serrano-Blanco
  • Jordi Alonso
  • Mireia Espallargues
  • J. Med. Internet Res..2020 Jun;doi: 10.2196/16388.Epub 2020-06-03.

雌のアフリカ産コメ癭蝿（Orseolia oryzivora Harris and Gagné）の電気生理学的・行動学的反応と宿主植物の揮発性物質に対する反応

Electrophysiological and behavioral responses of female African rice gall midge, Orseolia oryzivora Harris and Gagné, to host plant volatiles.
  • Emmanuel O Ogah
  • Lesley E Smart
  • Christine M Woodcock
  • John C Caulfield
  • Michael A Birkett
  • John A Pickett
  • Francis E Nwilene
  • Toby J Bruce
  • J. Chem. Ecol..2017 Jan;43(1):13-16. 10.1007/s10886-016-0788-6. doi: 10.1007/s10886-016-0788-6.Epub 2016-11-04.

声帯瘢痕および声帯溝に対する組換え肝細胞増殖因子を用いた耳内注射の第I/II相探索的臨床試験

A phase I/II exploratory clinical trial for intracordal injection of recombinant hepatocyte growth factor for vocal fold scar and sulcus.
  • Shigeru Hirano
  • Atsuhiko Kawamoto
  • Ichiro Tateya
  • Masanobu Mizuta
  • Yo Kishimoto
  • Nao Hiwatashi
  • Yoshitaka Kawai
  • Takuya Tsuji
  • Ryo Suzuki
  • Mami Kaneko
  • Yasushi Naito
  • Tatsuo Kagimura
  • Tatsuo Nakamura
  • Shin-Ichi Kanemaru
  • J Tissue Eng Regen Med.2018 04;12(4):1031-1038. doi: 10.1002/term.2603.Epub 2017-12-25.

ボトリosphaeranは、Walker-256 腫瘍担持肥満ラットにおける腫瘍の発生と癌性悪液質症候群を減衰させ、これらのラットの代謝学的および血液学的プロフィールを改善する

Botryosphaeran Attenuates Tumor Development and the Cancer Cachexia Syndrome in Walker-256 Tumor-Bearing Obese Rats and Improves the Metabolic and Hematological Profiles of These Rats.
  • Patrícia K Comiran
  • Mariana C Ribeiro
  • John H G Silva
  • Kamila O Martins
  • Izabella A Santos
  • Ana Emilia F Chiaradia
  • Amadeu Z Silva
  • Robert F H Dekker
  • Aneli M Barbosa-Dekker
  • Pâmela Alegranci
  • Eveline A I F Queiroz
  • Nutr Cancer.2020 Jul;:1-18. doi: 10.1080/01635581.2020.1789681.Epub 2020-07-08.

TRPV4はミトコンドリアの輸送を阻害し、CaMKIIに依存した細胞内Caの上昇を介して軸索変性を引き起こす

TRPV4 disrupts mitochondrial transport and causes axonal degeneration via a CaMKII-dependent elevation of intracellular Ca.
  • Brian M Woolums
  • Brett A McCray
  • Hyun Sung
  • Masashi Tabuchi
  • Jeremy M Sullivan
  • Kendra Takle Ruppell
  • Yunpeng Yang
  • Catherine Mamah
  • William H Aisenberg
  • Pamela C Saavedra-Rivera
  • Bryan S Larin
  • Alexander R Lau
  • Douglas N Robinson
  • Yang Xiang
  • Mark N Wu
  • Charlotte J Sumner
  • Thomas E Lloyd
  • Nat Commun.2020 May;11(1):2679. 10.1038/s41467-020-16411-5. doi: 10.1038/s41467-020-16411-5.Epub 2020-05-29.

CD74アイソフォームが41kDaに存在しないことで、ヒト肺腺癌由来細胞におけるCD74とCD44の異型関連が抑制される

Absence of CD74 Isoform at 41kDa Prevents the Heterotypic Associations between CD74 and CD44 in Human Lung Adenocarcinoma-derived Cells.
  • Waleed Al Abdulmonem
  • Zafar Rasheed
  • Abdullah S M Aljohani
  • Ola M Omran
  • Naila Rasheed
  • Abdullah Alkhamiss
  • Abdulaziz A M Al Salloom
  • Fahad Alhumaydhi
  • Mohamd A Alblihed
  • Hussain Al Ssadh
  • Muhammad Ismail Khan
  • Nelson Fernández
  • Immunol. Invest..2020 Jul;:1-15. doi: 10.1080/08820139.2020.1790594.Epub 2020-07-09.

潰瘍性大腸炎患者の実世界コホートにおけるトファシチニブの安全性

Safety of Tofacitinib in a Real-World Cohort of Patients With Ulcerative Colitis.
  • Parakkal Deepak
  • Quazim A Alayo
  • Aava Khatiwada
  • Bixuan Lin
  • Marc Fenster
  • Christina Dimopoulos
  • Geoffrey Bader
  • Roni Weisshof
  • Michael Jacobs
  • Alexandra Gutierrez
  • Matthew A Ciorba
  • George P Christophi
  • Anish Patel
  • Robert P Hirten
  • Jean-Frederic Colombel
  • David T Rubin
  • Christina Ha
  • Poonam Beniwal-Patel
  • Ryan C Ungaro
  • Gaurav Syal
  • Joel Pekow
  • Benjamin L Cohen
  • Andres Yarur
  • Clin. Gastroenterol. Hepatol..2020 Jul;S1542-3565(20)30913-7. doi: 10.1016/j.cgh.2020.06.050.Epub 2020-07-03.

金属汚染環境下で増殖した海洋神経毒性渦鞭毛藻Alexandrium pacificumの膜プロテオーム、細胞増殖、形態測定における異種間の変動性

Intraspecific variability in membrane proteome, cell growth, and morphometry of the invasive marine neurotoxic dinoflagellate Alexandrium pacificum grown in metal-contaminated conditions.
  • Cherif Chetouhi
  • Estelle Masseret
  • Cecilia Teodora Satta
  • Thierry Balliau
  • Mohamed Laabir
  • Natacha Jean
  • Sci. Total Environ..2020 May;715:136834. S0048-9697(20)30344-2. doi: 10.1016/j.scitotenv.2020.136834.Epub 2020-01-25.

大豆タンパク質単離物フィブリルと赤ビートルーツ由来のベタレインとの相互作用。大豆タンパク質単離物フィブリルとベタレインの相互作用：形態学、分光学的特性および熱安定性

Interaction of soy protein isolate fibrils with betalain from red beetroots: Morphology, spectroscopic characteristics and thermal stability.
  • Hui-Shuang Zhao
  • Zhen Ma
  • Pu Jing
  • Food Res. Int..2020 Sep;135:109289. S0963-9969(20)30314-8. doi: 10.1016/j.foodres.2020.109289.Epub 2020-05-05.

COVID-19で入院した最初の63人の成人患者の臨床的特徴と転帰。オマーンでの経験

Clinical characteristics and outcomes of the first 63 adult patients hospitalized with COVID-19: An experience from Oman.
  • Faryal Khamis
  • Ibrahim Al-Zakwani
  • Hamed Al Naamani
  • Sultan Al Lawati
  • Nenad Pandak
  • Muna Ba Omar
  • Maher Al Bahrani
  • Zakaryia Al Bulushi
  • Huda Al Khalili
  • Issa Al Salmi
  • Ruwaida Al Ismaili
  • Salah T Al Awaidy
  • J Infect Public Health.2020 Jul;13(7):906-913. S1876-0341(20)30496-2. doi: 10.1016/j.jiph.2020.06.002.Epub 2020-06-08.

原発性腋窩多汗症患者を対象としたUmeclidiniumの外用薬の薬物動態、安全性、忍容性および臨床効果を評価するための第2a相無作為化比較試験

A phase 2a randomized controlled study to evaluate the pharmacokinetic, safety, tolerability and clinical effect of topically applied Umeclidinium in subjects with primary axillary hyperhidrosis.
  • A Nasir
  • R Bissonnette
  • C Maari
  • J DuBois
  • T Pene Dumitrescu
  • J Haddad
  • Y Yamaguchi
  • M Dalessandro
  • J Eur Acad Dermatol Venereol.2018 Jan;32(1):145-151. doi: 10.1111/jdv.14651.Epub 2017-11-07.

CANVASプログラムにおけるカナグリフロジンとグルカゴン様ペプチド-1受容体アゴニストの併用療法の心血管リスクの中間マーカーに対する効果

The effects of combination canagliflozin and glucagon-like peptide-1 receptor agonist therapy on intermediate markers of cardiovascular risk in the CANVAS program.
  • Clare Arnott
  • Brendon L Neuen
  • Hiddo J L Heerspink
  • Gemma A Figtree
  • Mikhail Kosiborod
  • Carolyn S Lam
  • Christopher P Cannon
  • Norman Rosenthal
  • Wayne Shaw
  • Kenneth W Mahaffey
  • Meg J Jardine
  • Vlado Perkovic
  • Bruce Neal
  • Int. J. Cardiol..2020 Jun;S0167-5273(20)33389-1. doi: 10.1016/j.ijcard.2020.06.011.Epub 2020-06-20.

養子縁組前の逆境にある子どもの注意欠陥のリスクを調節する。家庭外プレースメントと子どもの強化されたエラーモニタリングのより短い期間の保護的役割

Moderating the Risk for Attention Deficits in Children with Pre-Adoptive Adversity: The Protective Role of Shorter Duration of out of Home Placement and Children's Enhanced Error Monitoring.
  • Tahl I Frenkel
  • Bonny Donzella
  • Kristin A Frenn
  • Sofie Rousseau
  • Nathan A Fox
  • Megan R Gunnar
  • J Abnorm Child Psychol.2020 Jun;10.1007/s10802-020-00671-2. doi: 10.1007/s10802-020-00671-2.Epub 2020-06-30.

Cycloarta-23-ene-3beta,25-diolはEuphorbia spinidens由来の五環ステロイドであり、分子ドッキングによるCOX阻害剤として、スイスの雄性マウスとWistarラットにおける鎮痛・抗炎症活性のin vivoでの研究を行った

Cycloarta-23-ene-3beta,25-diol a pentacyclic steroid from Euphorbia spinidens, as COX inhibitor with molecular docking, and in vivo study of its analgesic and anti-inflammatory activities in male Swiss mice and Wistar rats.
  • Valiollah Hajhashemi
  • Mustafa Ghanadian
  • Abbasali Palizaban
  • Karim Mahnam
  • Hamed Eshaghi
  • Bahareh Gheisari
  • Hojjat Sadeghi-Aliabadi
  • Prostaglandins Other Lipid Mediat..2020 Jul;:106473. S1098-8823(20)30066-6. doi: 10.1016/j.prostaglandins.2020.106473.Epub 2020-07-04.

公的ADL尺度を用いた入院患者の転倒予測モデルの開発：急性期医療における7,858人の患者を対象としたレトロスペクティブ観察研究

New predictive models for falls among inpatients using public ADL scale in Japan: A retrospective observational study of 7,858 patients in acute care setting.
  • Masaki Tago
  • Naoko E Katsuki
  • Yoshimasa Oda
  • Eiji Nakatani
  • Takashi Sugioka
  • Shu-Ichi Yamashita
  • PLoS ONE.2020;15(7):e0236130. PONE-D-20-14794. doi: 10.1371/journal.pone.0236130.Epub 2020-07-16.

バナナMaSPL16はリコピンβ-サイクラーゼ遺伝子の転写を活性化することで、果実の成熟期におけるカロテノイド生合成を調節する

Banana MaSPL16 Modulates Carotenoid Biosynthesis during Fruit Ripening through Activating the Transcription of Lycopene β-Cyclase Genes.
  • Li-Sha Zhu
  • Shu-Min Liang
  • Lu-Lu Chen
  • Chao-Jie Wu
  • Wei Wei
  • Wei Shan
  • Jian-Ye Chen
  • Wang-Jin Lu
  • Xin-Guo Su
  • Jian-Fei Kuang
  • J. Agric. Food Chem..2020 Feb;68(5):1286-1296. doi: 10.1021/acs.jafc.9b07134.Epub 2020-01-24.

糖尿病は不顕性頸動脈動脈硬化症と独立して関連している。非都市型地中海人集団における観察研究

Prediabetes Is Independently Associated with Subclinical Carotid Atherosclerosis: An Observational Study in a Non-Urban Mediterranean Population.
  • Maria Belén Vilanova
  • Josep Franch-Nadal
  • Mireia Falguera
  • Josep Ramon Marsal
  • Sílvia Canivell
  • Esther Rubinat
  • Neus Miró
  • Àngels Molló
  • Manel Mata-Cases
  • Mònica Gratacòs
  • Esmeralda Castelblanco
  • Dídac Mauricio
  • J Clin Med.2020 Jul;9(7). E2139. doi: 10.3390/jcm9072139.Epub 2020-07-07.

PD-L2/B7-DCの小型干渉RNAの局所適用によるサイレンシングは、接触過敏症の誘発を抑制する

Silencing of PD-L2/B7-DC by Topical Application of Small Interfering RNA Inhibits Elicitation of Contact Hypersensitivity.
  • Emi Furusawa
  • Tatsukuni Ohno
  • Shigenori Nagai
  • Taisei Noda
  • Takuya Komiyama
  • Katsunori Kobayashi
  • Hidetoshi Hamamoto
  • Michiyo Miyashin
  • Hiroo Yokozeki
  • Miyuki Azuma
  • J. Invest. Dermatol..2019 10;139(10):2164-2173.e1. S0022-202X(19)31474-5. doi: 10.1016/j.jid.2019.02.037.Epub 2019-04-09.

DRP1を介したミトコンドリアの分裂とマイトファジーの抑制は、低酸素環境下での肝細胞癌細胞のミトコンドリアのアポトーシスを増加させる

Suppressing DRP1-mediated mitochondrial fission and mitophagy increases mitochondrial apoptosis of hepatocellular carcinoma cells in the setting of hypoxia.
  • Xia-Hui Lin
  • Bai-Quan Qiu
  • Min Ma
  • Rui Zhang
  • Shu-Jung Hsu
  • Hua-Hua Liu
  • Jun Chen
  • Dong-Mei Gao
  • Jie-Feng Cui
  • Zheng-Gang Ren
  • Rong-Xin Chen
  • Oncogenesis.2020 Jul;9(7):67. 10.1038/s41389-020-00251-5. doi: 10.1038/s41389-020-00251-5.Epub 2020-07-13.

英国におけるSARS-CoV-2（PIMS-TS）と一時的に関連した小児炎症性多系統症候群の小児の集中治療入院：多施設観察研究

Intensive care admissions of children with paediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2 (PIMS-TS) in the UK: a multicentre observational study.
  • Patrick Davies
  • Claire Evans
  • Hari Krishnan Kanthimathinathan
  • Jon Lillie
  • Joseph Brierley
  • Gareth Waters
  • Mae Johnson
  • Benedict Griffiths
  • Pascale du Pré
  • Zoha Mohammad
  • Akash Deep
  • Stephen Playfor
  • Davinder Singh
  • David Inwald
  • Michelle Jardine
  • Oliver Ross
  • Nayan Shetty
  • Mark Worrall
  • Ruchi Sinha
  • Ashwani Koul
  • Elizabeth Whittaker
  • Harish Vyas
  • Barnaby R Scholefield
  • Padmanabhan Ramnarayan
  • Lancet Child Adolesc Health.2020 Jul;S2352-4642(20)30215-7. doi: 10.1016/S2352-4642(20)30215-7.Epub 2020-07-09.

エキスポネンシャルエンリッチメントによるリガンドの細胞系進化を利用した血症に対するDNAアプタマーの開発

Development of DNA Aptamers Against Blood Stages Using Cell-Systematic Evolution of Ligands by EXponential Enrichment.
  • Elena Lantero
  • Alexandros Belavilas-Trovas
  • Arnau Biosca
  • Paula Recolons
  • Ernest Moles
  • Elena Sulleiro
  • Francesc Zarzuela
  • Yunuen Ávalos-Padilla
  • Miriam Ramírez
  • Xavier Fernàndez-Busquets
  • J Biomed Nanotechnol.2020 Mar;16(3):315-334. doi: 10.1166/jbn.2020.2901.

南西インディアン・リッジ東部の深海堆積物から分離された海洋性多糖類産生菌アルテロモナス・ペラギモンタナ5.12の全ゲノム配列

Complete genome sequence of Alteromonas pelagimontana 5.12, a marine exopolysaccharide-producing bacterium isolated from hydrothermally influenced deep-sea sediment of eastern Southwest Indian Ridge.
  • Rupesh Kumar Sinha
  • K P Krishnan
  • P John Kurian
  • Mar Genomics.2020 Jul;:100804. S1874-7787(20)30065-9. doi: 10.1016/j.margen.2020.100804.Epub 2020-07-11.

適応的実験室進化により選抜されたKluyveromyces marxianus CCT 7735のエタノール耐性の評価

Assessment of ethanol tolerance of Kluyveromyces marxianus CCT 7735 selected by adaptive laboratory evolution.
  • Fernando Augusto da Silveira
  • Dalila Luzia de Oliveira Soares
  • Kyung Whan Bang
  • Thércia Rocha Balbino
  • Maurício Alexander de Moura Ferreira
  • Raphael Hermano Santos Diniz
  • Lorena Azevedo de Lima
  • Marcelo Mendes Brandão
  • Silas Granato Villas-Bôas
  • Wendel Batista da Silveira
  • Appl. Microbiol. Biotechnol..2020 Jul;10.1007/s00253-020-10768-9. doi: 10.1007/s00253-020-10768-9.Epub 2020-07-16.

COVID-19関連血栓症を二次性抗リン脂質抗体症候群に巻き込む。診断と治療の視点（レビュー）

Entangling COVID-19 associated thrombosis into a secondary antiphospholipid antibody syndrome: Diagnostic and therapeutic perspectives (Review).
  • Eugenio Cavalli
  • Alessia Bramanti
  • Rosella Ciurleo
  • Andrey I Tchorbanov
  • Antonio Giordano
  • Paolo Fagone
  • Cristina Belizna
  • Placido Bramanti
  • Yehuda Shoenfeld
  • Ferdinando Nicoletti
  • Int. J. Mol. Med..2020 Jun;doi: 10.3892/ijmm.2020.4659.Epub 2020-06-25.

肝虚血再灌流（I/R）傷害に対するジンセノサイドRg1の効果は、アポトーシスを阻害することにより、虚血再灌流誘発性肝障害を改善する

The effect of Ginsenoside Rg1 in hepatic ischemia reperfusion (I/R) injury ameliorates ischemia-reperfusion-induced liver injury by inhibiting apoptosis.
  • Jie Lin
  • Han-Fei Huang
  • Shi-Kun Yang
  • Jian Duan
  • Si-Ming Qu
  • Bo Yuan
  • Zhong Zeng
  • Biomed. Pharmacother..2020 Jun;129:110398. S0753-3322(20)30591-6. doi: 10.1016/j.biopha.2020.110398.Epub 2020-06-27.

セルロース分解性クロストリジアのペントースリン酸経路は、トランスアルドラーゼの代わりに６-ホスホフルクトキナーゼに依存している

The pentose phosphate pathway of cellulolytic clostridia relies on 6-phosphofructokinase instead of transaldolase.
  • Jeroen G Koendjbiharie
  • Shuen Hon
  • Martin Pabst
  • Robert Hooftman
  • David M Stevenson
  • Jingxuan Cui
  • Daniel Amador-Noguez
  • Lee R Lynd
  • Daniel G Olson
  • Richard van Kranenburg
  • J. Biol. Chem..2020 Feb;295(7):1867-1878. RA119.011239. doi: 10.1074/jbc.RA119.011239.Epub 2019-12-22.

患者の診察中に医療従事者が使用するコミュニケーション技術と補助具の分類法を開発する。システマティックレビューのためのプロトコル

Developing a Taxonomy of Communication Techniques and Aids Used By Healthcare Providers During Patient Consultations: Protocol for a Systematic Review.
  • Violetta Shersher
  • Terry P Haines
  • Cylie Williams
  • Louisa Willoughby
  • Elizabeth Sturgiss
  • Carolina Weller
  • JMIR Res Protoc.2020 Jul;9(7):e16801. v9i7e16801. doi: 10.2196/16801.Epub 2020-07-14.

メトトレキサート誘発性腎毒性に対するベルベリンの保護効果における Keap1/Nrf2、PMAPK/NF-κB および Bax/Bcl2/caspase-3 シグナル伝達経路の影響

The impact of Keap1/Nrf2, PMAPK/NF-κB and Bax/Bcl2/caspase-3 signaling pathways in the protective effects of berberine against methotrexate-induced nephrotoxicity.
  • Emad H M Hassanein
  • Abdel-Gawad S Shalkami
  • Marwa M Khalaf
  • Wafaa R Mohamed
  • Ramadan A M Hemeida
  • Biomed. Pharmacother..2019 Jan;109:47-56. S0753-3322(18)37048-3. doi: 10.1016/j.biopha.2018.10.088.Epub 2018-11-02.

注意欠陥/多動性障害の有無にかかわらず、治療を求める物質使用障害患者における初期の破壊的行動障害の発症と重症度

Onset and Severity of Early Disruptive Behavioral Disorders in Treatment-Seeking Substance Use Disorder Patients with and without Attention-Deficit/Hyperactivity Disorder.
  • Rafael A González
  • María C Vélez-Pastrana
  • Matthijs Blankers
  • Amanda Bäcker
  • Maija Konstenius
  • Martin Holtmann
  • Frances R Levin
  • Moritz Noack
  • Sharlene Kaye
  • Zsolt Demetrovics
  • Geurt van de Glind
  • Wim van den Brink
  • Arnt Schellekens
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血液透析患者における食事摂取量、臨床栄養状態、ホモシステイン：炎症の媒介的役割（NUGE-HD試験）

Dietary intake, clinical-nutritional status, and homocysteine in hemodialysis subjects: the mediating role of inflammation (NUGE-HD study).
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2021年東京オリンピックのためのエルゴジェニック補助剤としてのメントール。修正デルファイ法を用いた専門家主導のコンセンサス・ステートメント

Menthol as an Ergogenic Aid for the Tokyo 2021 Olympic Games: An Expert-Led Consensus Statement Using the Modified Delphi Method.
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  • Sports Med.2020 Jul;10.1007/s40279-020-01313-9. doi: 10.1007/s40279-020-01313-9.Epub 2020-07-04.

2008年から2018年にかけてマレーシアで報告されたヒトと動物の有病率に関するレビュー

A Review on the Prevalence of in Humans and Animals Reported in Malaysia from 2008-2018.
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  • Mohamad Aris Mohd Moklas
  • Malaika Watanabe
  • Norshariza Nordin
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COVID-19関連の不足に対応した呼吸器用個人保護具の迅速な除染のための乾熱およびマイクロ波発生蒸気プロトコル

Dry heat and microwave generated steam protocols for the rapid decontamination of respiratory personal protective equipment in response to COVID-19-related shortages.
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肝脾腫、肺炎、骨変化、前頭側頭型認知症。ニーマンピックB型とSQSTM1-related Paget's diseaseの同一個体での発症

Hepatosplenomegaly, pneumopathy, bone changes and fronto-temporal dementia: Niemann-Pick type B and SQSTM1-associated Paget's disease in the same individual.
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  • Elena Gonzalez Rodriguez
  • Catherine Beigelman-Aubry
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  • Belinda Campos-Xavier
  • Diana Ballhausen
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  • Luisa Bonafé
  • Andrea Superti-Furga
  • Christel Tran
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シストソーマ由来のフルクトース-1,6-ビスフォスフェートアルドラーゼとシスタチンによる1型糖尿病の改善に関する研究

Amelioration of type 1 diabetes by recombinant fructose-1,6-bisphosphate aldolase and cystatin derived from Schistosoma japonicum in a murine model.
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  • Bo Wang
  • Huabang Zhou
  • Qingli Luo
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  • Parasitol. Res..2020 Jan;119(1):203-214. 10.1007/s00436-019-06511-7. doi: 10.1007/s00436-019-06511-7.Epub 2019-12-16.

エクイヌ脂肪間葉系幹細胞におけるCRISPR/Cas9技術によるプロスタグランジンE2受容体EP2およびEP4のエディション

Edition of Prostaglandin E2 Receptors EP2 and EP4 by CRISPR/Cas9 Technology in Equine Adipose Mesenchymal Stem Cells.
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  • Joel Cabezas
  • José Manríquez
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  • Daniela Rojas
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  • Animals (Basel).2020 Jun;10(6). E1078. doi: 10.3390/ani10061078.Epub 2020-06-23.

遺伝的リスクと母親の子育てと精神病理と子供のADHDの症状と攻撃性の背景にある縦断的な伝達過程の役割を検討しています。プロスペクティブ養子縁組デザインの利点を利用して

Examining the Role of Genetic Risk and Longitudinal Transmission Processes Underlying Maternal Parenting and Psychopathology and Children's ADHD Symptoms and Aggression: Utilizing the Advantages of a Prospective Adoption Design.
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(S)-(-)-リモネンの局所適用は，ラットの損傷した骨格筋の酸化パラメータを改善するためにフォノフォレーシスと同様に有効である．

Topical application of (S)-(-)-limonene is as effective as phonophoresis for improving oxidative parameters of injured skeletal muscle in rats.
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  • Luís Fernando Sousa Filho
  • Jéssica Batista De Souza
  • José Evaldo Rodrigues De Menezes Filho
  • Thássio Ricardo Ribeiro Mesquita
  • Michel Santana Santos
  • Carla Maria Lins De Vasconcelos
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  • Naunyn Schmiedebergs Arch. Pharmacol..2020 Jul;10.1007/s00210-020-01941-y. doi: 10.1007/s00210-020-01941-y.Epub 2020-07-11.

分光光度法による解離力向上のための相対吸光度分布の概念。純度指数と均一性評価のためのツール

The concept of Relative Absorptivity Distribution for enhancing disbanding power of spectrophotometric technique to resolve co-formulated tablets: A tool for purity index and uniformity assessment.
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KORARCデータベース（730例の多施設ロボット根治的膀胱摘出術データベース）を用いた膀胱癌患者におけるロボット支援根治的膀胱摘出術後のpentafecta達成度に応じた腫瘍学的転帰

Oncological outcome according to attainment of pentafecta after robot assisted radical cystectomy among bladder cancer patients using KORARC database (730 multicenter robot radical cystectomy database).
  • Jong Jin Oh
  • Sangchul Lee
  • Ja Hyeon Ku
  • Tae Gyun Kwon
  • Tae-Hwan Kim
  • Seung Hyun Jeon
  • Sang Hyup Lee
  • Jong Kil Nam
  • Wan Seok Kim
  • Byong Chang Jeong
  • Ji Youl Lee
  • Sung Hoo Hong
  • Koon Ho Rha
  • Woong Kyu Han
  • Won Sik Ham
  • Young Goo Lee
  • Yong Seong Lee
  • Sung Yul Park
  • Young Eun Yoon
  • Sung Gu Kang
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  • BJU Int..2020 Jul;doi: 10.1111/bju.15178.Epub 2020-07-18.

アカミミズクモ（Trachemys scripta elegans）とカエデカメ（Graptemys spp.）における甲状腺ホルモン値と血漿毛細帯電気泳動の季節と性別による比較

A comparison of thyroid hormone levels and plasma capillary zone electrophoresis in red-eared sliders (Trachemys scripta elegans) and map turtles (Graptemys spp.) depending on season and sex.
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  • Rachel E Marschang
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  • Vet Clin Pathol.2020 Mar;49(1):78-90. doi: 10.1111/vcp.12838.Epub 2020-04-01.

植込み型除細動器を提供された患者に対するDECIDE-ICDの共有化されたDECISION SUPPORT Interventionの多施設共同試験。DECIDE-ICDの根拠、デザイン、メディケアの変更、パイロットデータ

A multicenter trial of a shared DECision Support Intervention for Patients offered implantable Cardioverter-DEfibrillators: DECIDE-ICD rationale, design, Medicare changes, and pilot data.
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  • Monica D Fitzgerald
  • Wendy S Tzou
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  • Am. Heart J..2020 Apr;226:161-173. S0002-8703(20)30116-2. doi: 10.1016/j.ahj.2020.04.010.Epub 2020-04-20.

新生児集中治療室に入院した早産児の入院期間の予測因子。院内での入院期間を予測するためには、入院期間を短縮することが重要である

Predictors of length of hospital stay among preterm infants admitted to neonatal intensive care unit: Data from a multicentre collaborative network from India (INNC: Indian National Neonatal Collaborative).
  • Srinivas Murki
  • Venkateshwarlu Vardhelli
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  • Dinesh Pawale
  • Dattatray Kulkarni
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  • Mangalabharathi Sundaram
  • Nishad Plakkal
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エチオピア北西部Debre Tabor町の生殖年齢女性のパートナーにおけるヒト免疫ウイルスの母子感染防止への男性の関与と関連因子：コミュニティに基づく横断的研究

Male involvement in prevention of mother to child transmission of human immuno virus and associated factors among partners' of reproductive age women at Debre Tabor town, Northwest Ethiopia: a community based cross sectional study.
  • Enyew Dagnew
  • Miteku Andualem
  • Temesegen Worku
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  • Wubet Taklual
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大動脈経カテーテル大動脈弁留置術を受けた患者に対する意識的鎮静のみと比較した併用催眠療法の周術期成績

Perioperative Outcomes of Adjunctive Hypnotherapy Compared with Conscious Sedation Alone for Patients Undergoing Transfemoral Transcatheter Aortic Valve Implantation.
  • Masao Takahashi
  • Gauthier Mouillet
  • Asmaa Khaled
  • Madjid Boukantar
  • Romain Gallet
  • Vladimir Rubimbura
  • Pascal Lim
  • Jean-Luc Dubois-Rande
  • Emmanuel Teiger
  • Int Heart J.2020 Jan;61(1):60-66. doi: 10.1536/ihj.19-296.Epub 2020-01-17.

視床下部発生の分子設計

Molecular design of hypothalamus development.
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  • Solomiia Korchynska
  • Konstantin Popadin
  • Marco Benevento
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  • Francois Lallemend
  • Katsuhiko Nishimori
  • Frédéric Clotman
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  • Matthias Farlik
  • Christoph Bock
  • Igor Adameyko
  • Tomas Hökfelt
  • Erik Keimpema
  • Tibor Harkany
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欧州における健康研究の分断化の克服：COVID-19からの教訓

Overcoming fragmentation of health research in Europe: lessons from COVID-19.
  • Karin R Sipido
  • Fernando Antoñanzas
  • Julio Celis
  • Laurent Degos
  • Richard Frackowiak
  • Valentin Fuster
  • Detlev Ganten
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  • Hans Hofstraat
  • Stephen T Holgate
  • Gabriel Krestin
  • Michael Manns
  • Francoise Meunier
  • Wolfgang Oertel
  • Susanna Palkonen
  • Dainius Pavalkis
  • Helga Rübsamen-Schaeff
  • Ulf Smith
  • Bente Merete Stallknecht
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ミリ秒 H/D 交換質量分析を使用した血管内皮成長因子 A の拡張コンストラクト上での臨床前の Bevacizumab (Avastin) バイオシミラーのエピトープ マッピング

Epitope Mapping for a Pre-Clinical Bevacizumab (Avastin) Biosimilar on an Extended Construct of Vascular Endothelial Growth Factor-A using Millisecond H/D Exchange Mass Spectrometry.
  • Kerene A Brown
  • Cristina Lento
  • Shanthi Rajendran
  • Jason Dowd
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  • Biochemistry.2020 Jul;doi: 10.1021/acs.biochem.0c00308.Epub 2020-07-16.

ノースカロライナ州におけるMPID-NGSによる最近のHIV感染、薬剤耐性変異、および感染ネットワークのほぼリアルタイム同定

Near Real-Time Identification of Recent HIV Transmissions, Transmitted Drug Resistance Mutations, and Transmission Networks by MPID-NGS in North Carolina.
  • Shuntai Zhou
  • Sabrina Sizemore
  • Matt Moeser
  • Scott Zimmerman
  • Erika Samoff
  • Victoria Mobley
  • Simon Frost
  • Andy Cressman
  • Michael Clark
  • Tara Skelly
  • Hemant Kelkar
  • Umadevi Veluvolu
  • Corbin Jones
  • Joseph Eron
  • Myron Cohen
  • Julie A E Nelson
  • Ronald Swanstrom
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  • J. Infect. Dis..2020 Jul;jiaa417. doi: 10.1093/infdis/jiaa417.Epub 2020-07-14.

Plasmodium vivax Merozoite Surface Protein 3αに対する相補固定抗体の誘導と動態、免疫グロブリンGサブクラスおよび免疫グロブリンMとの関係について

Induction and Kinetics of Complement-Fixing Antibodies Against Plasmodium vivax Merozoite Surface Protein 3α and Relationship With Immunoglobulin G Subclasses and Immunoglobulin M.
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  • Timothy William
  • Jianlin Jiang
  • Mary R Galinski
  • Freya J I Fowkes
  • Matthew J Grigg
  • James G Beeson
  • Nicholas M Anstey
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  • J. Infect. Dis..2019 11;220(12):1950-1961. 5550848. doi: 10.1093/infdis/jiz407.

ミノサイクリンとメチルプレドニゾロンの併用治療が実験的脊髄損傷における腫瘍壊死因子αとインターロイキン-6の発現に及ぼす影響：光と電子顕微鏡による研究

Effects of combined treatment of minocycline and methylprednisolone on the expression of tumor necrosis factor alpha and interleukine-6 in experimental spinal cord injury: a light and electron microscopic study.
  • Leman Sencar
  • Derviş Mansuri Yilmaz
  • Abdullah Tuli
  • Sait Polat
  • Ultrastruct Pathol.2020 Jun;:1-17. doi: 10.1080/01913123.2020.1771493.Epub 2020-06-22.

羽毛型TCF7L2はニコチン中毒と糖尿病を結びつける

Habenular TCF7L2 links nicotine addiction to diabetes.
  • Alexander Duncan
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  • Stephanie P B Caligiuri
  • Xin-An Liu
  • Zuxin Chen
  • Maria Vittoria Micioni Di Bonaventura
  • Karim S Elayouby
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  • Purva Bali
  • Clementine Fillinger
  • Maya Williams
  • Richard M O'Connor
  • Zichen Wang
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  • Ines Ibanez-Tallon
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  • Nature.2019 10;574(7778):372-377. 10.1038/s41586-019-1653-x. doi: 10.1038/s41586-019-1653-x.Epub 2019-10-16.

チチンのC末端PEVKエクソンを削除すると、受動的な筋剛性が増加し、スプライシングが変化し、骨格筋の断面および縦方向の肥大が誘導されることが明らかになった

Deleting Titin's C-Terminal PEVK Exons Increases Passive Stiffness, Alters Splicing, and Induces Cross-Sectional and Longitudinal Hypertrophy in Skeletal Muscle.
  • Robbert J van der Pijl
  • Brian Hudson
  • Tomotaroh Granzier-Nakajima
  • Frank Li
  • Anne M Knottnerus
  • John Smith
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  • Michael Gotthardt
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心筋β-アドレナリン受容体の活性化は、コンネキシン43の発現と分布における細胞タイプ依存性の異なる変化を媒介する

Cardiac β-adrenergic receptor activation mediates distinct and cell type-dependent changes in the expression and distribution of connexin 43.
  • Yi Zhang
  • Meng-Chen Hou
  • Jing-Jing Li
  • Ying Qi
  • Yu Zhang
  • Gang She
  • Yu-Jie Ren
  • Wei Wu
  • Zheng-Da Pang
  • Wenjun Xie
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  • Xiao-Jun Du
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グリーンルーフの5年間の運用において、廃材をグリーンルーフ下地として再利用することで、グリーンルーフからの炭素排出を効果的に抑制できるかどうか？

Whether the carbon emission from green roofs can be effectively mitigated by recycling waste building material as green roof substrate during five-year operation?
  • Liangqian Fan
  • Jingting Wang
  • Xiaoling Liu
  • Hongbing Luo
  • Ke Zhang
  • Xiaoying Fu
  • Mei Li
  • Xiaoting Li
  • Bing Jiang
  • Jia Chen
  • Shuzhi Fu
  • You Mo
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  • Wei Chen
  • Lin Cheng
  • Fenghui Chen
  • Lin Ji
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悪性尿路閉塞症治療における二重JカテーテルのAntegrade挿入：大学病院における修正術式で得られた結果のレトロスペクティブ解析

Antegrade insertion of a double J catheter in the treatment of malignant ureteral obstruction: a retrospective analysis of the results obtained with a modified technique at a university hospital.
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  • Tiago Kojun Tibana
  • Edson Marchiori
  • Thiago Franchi Nunes
  • Radiol Bras.2020 May-Jun;53(3):155-160. doi: 10.1590/0100-3984.2019.0090.

BDNFの過剰発現は線条体神経細胞のD3受容体レベルを増加させ、D1受容体アゴニスト誘発性ジスキネジアを悪化させる

BDNF Overexpression Increases Striatal D3 Receptor Level at Striatal Neurons and Exacerbates D1-Receptor Agonist-Induced Dyskinesia.
  • Simona Scheggi
  • Francesca Rossi
  • Sara Corsi
  • Silvia Fanni
  • Elisabetta Tronci
  • Congiu Ludovica
  • Romina Vargiu
  • Carla Gambarana
  • Ana Muñoz
  • Roberto Stancampiano
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  • Manolo Carta
  • J Parkinsons Dis.2020 Jul;JPD202061. doi: 10.3233/JPD-202061.Epub 2020-07-08.

ヒストン脱アセチル化酵素6/8とブロモドメインBRPF1のデュアルターゲティング阻害剤の設計、合成、生物学的評価

Design, synthesis, and biological evaluation of dual targeting inhibitors of histone deacetylase 6/8 and bromodomain BRPF1.
  • Ehab Ghazy
  • Patrik Zeyen
  • Daniel Herp
  • Martin Hügle
  • Karin Schmidtkunz
  • Frank Erdmann
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  • Christophe Romier
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  • Manfred Jung
  • Wolfgang Sippl
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Mthfd2はミトコンドリア機能とDNA修復を調節し、マウス幹細胞の多能性を維持する

Mthfd2 Modulates Mitochondrial Function and DNA Repair to Maintain the Pluripotency of Mouse Stem Cells.
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  • Yangli Pei
  • Liang Zhong
  • Henry Yang
  • Yanliang Wang
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  • Naixin Chen
  • Qianqian Zhu
  • Jie Gao
  • Minglei Zhi
  • Bingqiang Wen
  • Shaopeng Zhang
  • Jinzhu Xiang
  • Qingqing Wei
  • Hui Liang
  • Suying Cao
  • Huiqiang Lou
  • Zhongzhou Chen
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  • Stem Cell Reports.2020 Jul;S2213-6711(20)30239-3. doi: 10.1016/j.stemcr.2020.06.018.Epub 2020-07-02.

リンパ性新生物における全ゲノムシークエンシングから免疫グロブリン遺伝子再配列と発がん性転座を再構築するためのIgCaller

IgCaller for reconstructing immunoglobulin gene rearrangements and oncogenic translocations from whole-genome sequencing in lymphoid neoplasms.
  • Ferran Nadeu
  • Rut Mas-de-Les-Valls
  • Alba Navarro
  • Romina Royo
  • Silvia Martín
  • Neus Villamor
  • Helena Suárez-Cisneros
  • Rosó Mares
  • Junyan Lu
  • Anna Enjuanes
  • Alfredo Rivas-Delgado
  • Marta Aymerich
  • Tycho Baumann
  • Dolors Colomer
  • Julio Delgado
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  • Xose S Puente
  • Peter J Campbell
  • Sílvia Beà
  • Francesco Maura
  • Elías Campo
  • Nat Commun.2020 Jul;11(1):3390. 10.1038/s41467-020-17095-7. doi: 10.1038/s41467-020-17095-7.Epub 2020-07-07.

Corrigendum to "Partial least squares and linear support vector regression chemometric models for analysis of Norfloxacin and Tinidazole with Tinidazole impurity" Spectrochim.Acta A: Mol.Biomol.Spectrosc.239巻、2020年10月5日、118513

Corrigendum to "Partial least squares and linear support vector regression chemometric models for analysis of Norfloxacin and Tinidazole with Tinidazole impurity" [Spectrochim. Acta A: Mol. Biomol. Spectrosc. Volume 239, 5 October 2020, 118513].
  • Ibrahim A Naguib
  • Eglal A Abdelaleem
  • Eman S Hassan
  • Nouruddin W Ali
  • Mohammed Gamal
  • Spectrochim Acta A Mol Biomol Spectrosc.2020 Jul;241:118696. S1386-1425(20)30675-2. doi: 10.1016/j.saa.2020.118696.Epub 2020-07-13.

腎生検後の糸球体腎炎患者におけるがん発症と死亡率の差：単一施設レトロスペクティブコホート研究

Cancer development and mortality differences in patients with glomerulonephritis after renal biopsy: a single center retrospective cohort study.
  • Hyunjin Ryu
  • Kipyo Kim
  • Jiwon Ryu
  • Hyung-Eun Son
  • Ji-Young Ryu
  • Sejoong Kim
  • Ki Young Na
  • Dong Wan Chae
  • Ho Jun Chin
  • BMC Nephrol.2020 Jun;21(1):221. 10.1186/s12882-020-01882-x. doi: 10.1186/s12882-020-01882-x.Epub 2020-06-10.

クレードF AAVHSCは、非ヒト霊長類に静脈内投与した後、血液脳関門を通過し、末梢組織に加えて中枢神経系にも導入されます

Clade F AAVHSCs cross the blood brain barrier and transduce the central nervous system in addition to peripheral tissues following intravenous administration in nonhuman primates.
  • Jeff L Ellsworth
  • Jacinthe Gingras
  • Laura J Smith
  • Hillard Rubin
  • Tania A Seabrook
  • Kruti Patel
  • Nicole Zapata
  • Kevin Olivieri
  • Michael O'Callaghan
  • Elizabeth Chlipala
  • Pablo Morales
  • Albert Seymour
  • PLoS ONE.2019;14(11):e0225582. PONE-D-19-21158. doi: 10.1371/journal.pone.0225582.Epub 2019-11-26.

副産物の価値化に伴う課題-超音波処理した植物由来副産物と発酵させた植物由来副産物の安全性パラメータの比較研究

Challenges Associated with Byproducts Valorization-Comparison Study of Safety Parameters of Ultrasonicated and Fermented Plant-Based Byproducts.
  • Elena Bartkiene
  • Vadims Bartkevics
  • Iveta Pugajeva
  • Anastasija Borisova
  • Egle Zokaityte
  • Vita Lele
  • Vytaute Sakiene
  • Paulina Zavistanaviciute
  • Dovile Klupsaite
  • Daiva Zadeike
  • Fatih Özogul
  • Grazina Juodeikiene
  • Foods.2020 May;9(5). E614. doi: 10.3390/foods9050614.Epub 2020-05-11.

PCAREとWASF3は、光受容体外側セグメントディスク形成の開始に必要な毛様体F-アクチンアセンブリを制御しています

PCARE and WASF3 regulate ciliary F-actin assembly that is required for the initiation of photoreceptor outer segment disk formation.
  • Julio C Corral-Serrano
  • Ideke J C Lamers
  • Jeroen van Reeuwijk
  • Lonneke Duijkers
  • Anita D M Hoogendoorn
  • Adem Yildirim
  • Nikoleta Argyrou
  • Renate A A Ruigrok
  • Stef J F Letteboer
  • Rossano Butcher
  • Max D van Essen
  • Sanae Sakami
  • Sylvia E C van Beersum
  • Krzysztof Palczewski
  • Michael E Cheetham
  • Qin Liu
  • Karsten Boldt
  • Uwe Wolfrum
  • Marius Ueffing
  • Alejandro Garanto
  • Ronald Roepman
  • Rob W J Collin
  • Proc. Natl. Acad. Sci. U.S.A..2020 May;117(18):9922-9931. 1903125117. doi: 10.1073/pnas.1903125117.Epub 2020-04-20.

グリオブラストーマの骨髄由来サプレッサー細胞サブセットは、免疫抑制を低減するために標的化できるマクロファージ移行阻害因子受容体のプロファイルを異なる形で発現している

Glioblastoma Myeloid-Derived Suppressor Cell Subsets Express Differential Macrophage Migration Inhibitory Factor Receptor Profiles That Can Be Targeted to Reduce Immune Suppression.
  • Tyler J Alban
  • Defne Bayik
  • Balint Otvos
  • Anja Rabljenovic
  • Lin Leng
  • Leu Jia-Shiun
  • Gustavo Roversi
  • Adam Lauko
  • Arbaz A Momin
  • Alireza M Mohammadi
  • David M Peereboom
  • Manmeet S Ahluwalia
  • Kazuko Matsuda
  • Kyuson Yun
  • Richard Bucala
  • Michael A Vogelbaum
  • Justin D Lathia
  • Front Immunol.2020;11:1191. doi: 10.3389/fimmu.2020.01191.Epub 2020-06-18.

COVID-19 を有する成人入院患者における短期生存率を予測するためのリスク因子に基づくシステムの開発と検証：多施設，レトロスペクティブ，コホート研究

Development and validation of a risk factor-based system to predict short-term survival in adult hospitalized patients with COVID-19: a multicenter, retrospective, cohort study.
  • Shuai Zhang
  • Mengfei Guo
  • Limin Duan
  • Feng Wu
  • Guorong Hu
  • Zhihui Wang
  • Qi Huang
  • Tingting Liao
  • Juanjuan Xu
  • Yanling Ma
  • Zhilei Lv
  • Wenjing Xiao
  • Zilin Zhao
  • Xueyun Tan
  • Daquan Meng
  • Shujing Zhang
  • E Zhou
  • Zhengrong Yin
  • Wei Geng
  • Xuan Wang
  • Jianchu Zhang
  • Jianguo Chen
  • Yu Zhang
  • Yang Jin
  • Crit Care.2020 Jul;24(1):438. 10.1186/s13054-020-03123-x. doi: 10.1186/s13054-020-03123-x.Epub 2020-07-16.

加齢マウスにおけるセラミド発現の組織特異的スクリーニングにより、骨格筋の繊維サイズと強度の潜在的な調節因子としてセラミド合成酵素-1とセラミド合成酵素-5が同定された

A tissue-specific screen of ceramide expression in aged mice identifies ceramide synthase-1 and ceramide synthase-5 as potential regulators of fiber size and strength in skeletal muscle.
  • Bettina Tosetti
  • Susanne Brodesser
  • Anna Brunn
  • Martina Deckert
  • Matthias Blüher
  • Wolfram Doehner
  • Stefan D Anker
  • Daniela Wenzel
  • Bernd Fleischmann
  • Carola Pongratz
  • Franziska Peters
  • Olaf Utermöhlen
  • Martin Krönke
  • Aging Cell.2020 01;19(1):e13049. doi: 10.1111/acel.13049.Epub 2019-11-06.

一般的なピピストレルPipistrellleus pipistrellus (Chiroptera: Vespertilionidae)とコウモリ軟ダニArgas vespertilionis (Ixodida: Argasidae)におけるRickettsiae

Rickettsiae in the common pipistrelle Pipistrellus pipistrellus (Chiroptera: Vespertilionidae) and the bat soft tick Argas vespertilionis (Ixodida: Argasidae).
  • Shuo Zhao
  • Meihua Yang
  • Gang Liu
  • Sándor Hornok
  • Shanshan Zhao
  • Chunli Sang
  • Wenbo Tan
  • Yuanzhi Wang
  • Parasit Vectors.2020 Jan;13(1):10. 10.1186/s13071-020-3885-x. doi: 10.1186/s13071-020-3885-x.Epub 2020-01-09.

インテグリンαvβ3を用いた新血管新生のイメージ化のための有望なターゲットとしてのインテグリンαvβ3のインハウスジェネレーター産生ポジトロンエミッター(68)Ga標識DOTA-アルギニン-グリシン-アスパラギン酸(RGD)リガンドを用いた研究

Integrin αvβ3 as a Promising Target to Image Neoangiogenesis Using In-House Generator-Produced Positron Emitter (68)Ga-Labeled DOTA-Arginine-Glycine-Aspartic Acid (RGD) Ligand.
  • Rakhee Vatsa
  • Priya Bhusari
  • Sunil Kumar
  • Sudipta Chakraborty
  • Ashutosh Dash
  • Gurpreet Singh
  • Devinder Kumar Dhawan
  • Jaya Shukla
  • Bhagwant Rai Mittal
  • Cancer Biother. Radiopharm..2015 Jun;30(5):217-24. doi: 10.1089/cbr.2014.1781.

インテグリン(α)vbeta3/焦点接着キナーゼ(FAK)/ホスファチジルイノシトール3-キナーゼ(PI3K)/タンパク質キナーゼB-セリン/スレオニンキナーゼ(AKT)シグナル伝達経路を利用した細胞生存における細胞外マトリックス腎尿細管間質性腎炎抗原(TINag)の役割

Role of extracellular matrix renal tubulo-interstitial nephritis antigen (TINag) in cell survival utilizing integrin (alpha)vbeta3/focal adhesion kinase (FAK)/phosphatidylinositol 3-kinase (PI3K)/protein kinase B-serine/threonine kinase (AKT) signaling pathway.
  • Ping Xie
  • Vinay K Kondeti
  • Sun Lin
  • Yoshisuke Haruna
  • Kirtee Raparia
  • Yashpal S Kanwar
  • J. Biol. Chem..2011 Sep;286(39):34131-46. M111.241778. doi: 10.1074/jbc.M111.241778.Epub 2011-07-27.

感染により誘発されたラットにおけるマクロファージ遊走阻害因子（MIF）発現に及ぼす第一次根絶レジメンへのスネークヘッドフィッシュ抽出物の補充の効果を検討した

The effect of snakehead fish extract supplementation to first-line eradication regimen on macrophage migration inhibitory factor (MIF) expression in rats induced by infection.
  • O K Yulizal
  • Aznan Lelo
  • Syafruddin Ilyas
  • Raden Lia Kusumawati
  • J Adv Vet Anim Res.2020 Jun;7(2):209-217. doi: 10.5455/javar.2020.g411.Epub 2020-05-08.

F-SMBT-1: モノアミン酸化酵素Bイメージングのための選択的かつ可逆的なポジトロン断層撮影トレーサー

F-SMBT-1: A Selective and Reversible Positron-Emission Tomography Tracer for Monoamine Oxidase-B Imaging.
  • Ryuichi Harada
  • Yoshimi Hayakawa
  • Michinori Ezura
  • Pradith Lerdsirisuk
  • Yiqing Du
  • Yoichi Ishikawa
  • Ren Iwata
  • Miho Shidahara
  • Aiko Ishiki
  • Akio Kikuchi
  • Hiroyuki Arai
  • Yukitsuka Kudo
  • Kazuhiko Yanai
  • Shozo Furumoto
  • Nobuyuki Okamura
  • J. Nucl. Med..2020 Jul;jnumed.120.244400. doi: 10.2967/jnumed.120.244400.Epub 2020-07-09.

末梢的に作用するオピオイド受容体拮抗薬ナルデメダインの薬理学的プロフィール。ナロキソンおよびナロキセゴールとの比較

Pharmacological Profile of Naldemedine, a Peripherally Acting -Opioid Receptor Antagonist: Comparison with Naloxone and Naloxegol.
  • Toshiyuki Kanemasa
  • Katsumi Koike
  • Kenji Takase
  • Tohko Arai
  • Atsushi Nakamura
  • Yasuhide Morioka
  • Minoru Hasegawa
  • J. Pharmacol. Exp. Ther..2020 Jun;373(3):438-444. jpet.119.264515. doi: 10.1124/jpet.119.264515.Epub 2020-03-13.

旧・新世界8カ国のコウモリダニ（Acari: Ixodidae, Argasidae）におけるベクター媒介性細菌の分子検出

Molecular detection of vector-borne bacteria in bat ticks (Acari: Ixodidae, Argasidae) from eight countries of the Old and New Worlds.
  • Sándor Hornok
  • Krisztina Szőke
  • Marina L Meli
  • Attila D Sándor
  • Tamás Görföl
  • Péter Estók
  • Yuanzhi Wang
  • Vuong Tan Tu
  • Dávid Kováts
  • Sándor A Boldogh
  • Alexandra Corduneanu
  • Kinga M Sulyok
  • Miklós Gyuranecz
  • Jenő Kontschán
  • Nóra Takács
  • Ali Halajian
  • Sara Epis
  • Regina Hofmann-Lehmann
  • Parasit Vectors.2019 Jan;12(1):50. 10.1186/s13071-019-3303-4. doi: 10.1186/s13071-019-3303-4.Epub 2019-01-22.

EU 域外の L.A.のウイルスおよびビロイドの有害生物分類

Pest categorisation of non-EU viruses and viroids of L.
  • Claude Bragard
  • Katharina Dehnen-Schmutz
  • Paolo Gonthier
  • Marie-Agnès Jacques
  • Josep Anton Jaques Miret
  • Annemarie Fejer Justesen
  • Alan MacLeod
  • Christer Sven Magnusson
  • Panagiotis Milonas
  • Juan A Navas-Cortes
  • Stephen Parnell
  • Roel Potting
  • Philippe Lucien Reignault
  • Hans-Hermann Thulke
  • Wopke Van der Werf
  • Antonio Vicent Civera
  • Jonathan Yuen
  • Lucia Zappalà
  • Thierry Candresse
  • Elisavet Chatzivassiliou
  • Franco Finelli
  • Giovanni Paolo Martelli
  • Stephan Winter
  • Domenico Bosco
  • Michela Chiumenti
  • Francesco Di Serio
  • Tomasz Kaluski
  • Angelantonio Minafra
  • Luisa Rubino
  • EFSA J.2019 Sep;17(9):e05669. EFS25669. doi: 10.2903/j.efsa.2019.5669.Epub 2019-09-30.

パーキンソン病における衝動性に関連した大規模なネットワーク間接続性の増加

Increased large-scale inter-network connectivity in relation to impulsivity in Parkinson's disease.
  • Jinsoo Koh
  • Yoshiki Kaneoke
  • Tomohiro Donishi
  • Takuya Ishida
  • Mayumi Sakata
  • Yasuhiro Hiwatani
  • Yoshiaki Nakayama
  • Masaaki Yasui
  • Hiroshi Ishiguchi
  • Masaya Hironishi
  • Ken-Ya Murata
  • Masaki Terada
  • Hidefumi Ito
  • Sci Rep.2020 Jul;10(1):11418. 10.1038/s41598-020-68266-x. doi: 10.1038/s41598-020-68266-x.Epub 2020-07-10.

間隔盲腸手術は本当に必要か？複雑な虫垂炎を合併した後に間隔をあけて盲腸手術を受けた成人患者の新生物率を詳しく見てみましょう

Is interval appendectomy really needed? A closer look at neoplasm rates in adult patients undergoing interval appendectomy after complicated appendicitis.
  • Danielle Hayes
  • Shelby Reiter
  • Edard Hagen
  • Gary Lucas
  • Isabelle Chu
  • Tobias Muñiz
  • Ryan Martinez
  • Surg Endosc.2020 Jul;10.1007/s00464-020-07798-9. doi: 10.1007/s00464-020-07798-9.Epub 2020-07-16.

Roux-en-Y再建を伴う胃全摘術後の空腸近位部非吻合性狭窄に対する磁気圧迫吻合術：症例報告

Magnetic compression anastomosis for non-anastomotic stenosis of the proximal jejunum after total gastrectomy with Roux-en-Y reconstruction: a case report.
  • Teppei Kamada
  • Hironori Ohdaira
  • Hideyuki Takeuchi
  • Junji Takahashi
  • Rui Marukuchi
  • Norihiko Suzuki
  • Satoshi Narihiro
  • Sojun Hoshimoto
  • Masashi Yoshida
  • Eigoro Yamanouchi
  • Yutaka Suzuki
  • Surg Case Rep.2020 Jul;6(1):167. 10.1186/s40792-020-00932-8. doi: 10.1186/s40792-020-00932-8.Epub 2020-07-09.

中国東北部の下痢性動物から分離されたProteus mirabilisのバイオフィルム形成、病原性遺伝子発現、抗生物質耐性との関連

Association among biofilm formation, virulence gene expression, and antibiotic resistance in Proteus mirabilis isolates from diarrhetic animals in Northeast China.
  • Yadong Sun
  • Shanshan Wen
  • Lili Zhao
  • Qiqi Xia
  • Yue Pan
  • Hanghang Liu
  • Chengwei Wei
  • Hongyan Chen
  • Junwei Ge
  • Hongbin Wang
  • BMC Vet. Res..2020 Jun;16(1):176. 10.1186/s12917-020-02372-w. doi: 10.1186/s12917-020-02372-w.Epub 2020-06-05.

Phanerochaete carnosaのミトコンドリアゲノムは206kbpであり、イントロンの動態、繰り返し配列の蓄積、プラスミド由来の遺伝子などが明らかになっている

The 206 kbp mitochondrial genome of Phanerochaete carnosa reveals dynamics of introns, accumulation of repeat sequences and plasmid-derived genes.
  • Xu Wang
  • Andong Song
  • Fengqin Wang
  • Mingyue Chen
  • Xiao Li
  • Qiang Li
  • Na Liu
  • Int. J. Biol. Macromol..2020 Jun;162:209-219. S0141-8130(20)33586-8. doi: 10.1016/j.ijbiomac.2020.06.142.Epub 2020-06-18.

胃癌に対するBillroth Ⅰ再建術による遠位胃切除術後の逆流性食道炎に塩酸アコチアミドが有効であった1例

[A Case in Which Acotiamide Hydrochloride Was Effective for Reflux Esophagitis after Distal Gastrectomy with Billroth Ⅰ Reconstruction for Gastric Cancer].
  • Yukio Maezawa
  • Toru Aoyama
  • Junya Morita
  • Kazuki Kano
  • Shinya Amano
  • Sho Sawazaki
  • Masakatsu Numata
  • Tsutomu Hayashi
  • Takanobu Yamada
  • Tsutomu Sato
  • Takashi Ohshima
  • Norio Yukawa
  • Takaki Yoshikawa
  • Munetaka Masuda
  • Yasushi Rino
  • Gan To Kagaku Ryoho.2019 Mar;46(3):595-597.

皮質拡散性脱分極により誘発される顔面痛覚過敏、羞明、運動機能低下は、スマトリプタンとオルセゲパントにより改善される

Cortical spreading depolarisation-induced facial hyperalgesia, photophobia and hypomotility are ameliorated by sumatriptan and olcegepant.
  • Chunhua Tang
  • Miyuki Unekawa
  • Satoshi Kitagawa
  • Tsubasa Takizawa
  • Yohei Kayama
  • Jin Nakahara
  • Mamoru Shibata
  • Sci Rep.2020 Jul;10(1):11408. 10.1038/s41598-020-67948-w. doi: 10.1038/s41598-020-67948-w.Epub 2020-07-10.

m-トリフルオロメチルジフェニルジセレニド（m-CF-PhSe）は、海馬の神経毒性適応を調節し、マウスの短期モルヒネ離脱における抑うつ症状に似た表現型を廃止する

m-Trifluoromethyl-diphenyl diselenide (m-CF-PhSe) modulates the hippocampal neurotoxic adaptations and abolishes a depressive-like phenotype in a short-term morphine withdrawal in mice.
  • Carolina C Martins
  • Suzan G Rosa
  • Ana M S Recchi
  • Cristina W Nogueira
  • Gilson Zeni
  • Prog. Neuropsychopharmacol. Biol. Psychiatry.2020 03;98:109803. S0278-5846(19)30576-7. doi: 10.1016/j.pnpbp.2019.109803.Epub 2019-11-02.

RITA仮浸漬系で培養したBENTH.の成長および二次代謝物蓄積に及ぼすスペルミンおよび窒素欠乏の影響

Influence of spermine and nitrogen deficiency on growth and secondary metabolites accumulation in Benth. cultured in a RITA temporary immersion system.
  • Elizabeth Rubio-Rodríguez
  • Alma Rosa López-Laredo
  • Virginia Medina-Pérez
  • Gabriela Trejo-Tapia
  • José Luis Trejo-Espino
  • Eng. Life Sci..2019 Dec;19(12):944-954. ELSC1261. doi: 10.1002/elsc.201900040.Epub 2019-09-19.

消化管微生物群集の変化は、免疫チェックポイント遮断に対するHIV特異的CD8+ T細胞の反応性に影響を与える

Changes in gastrointestinal microbial communities influence HIV-specific CD8+ T-cell responsiveness to immune checkpoint blockade.
  • Ivo N SahBandar
  • Glen M Chew
  • Michael J Corley
  • Alina P S Pang
  • Naoky Tsai
  • Nancy Hanks
  • Vedbar S Khadka
  • Nichole R Klatt
  • Tiffany Hensley-McBain
  • Ma Somsouk
  • Ivan Vujkovic-Cvijin
  • Dominic C Chow
  • Cecilia M Shikuma
  • Lishomwa C Ndhlovu
  • AIDS.2020 Aug;34(10):1451-1460. 00002030-202008010-00003. doi: 10.1097/QAD.0000000000002557.

キュミル-5F-P7AICAを用いた7-アザインドール由来合成カンナビノイドの代謝パターン解明のためのin vitroモデルとin vivoモデルの比較

Comparison of in vitro and in vivo models for the elucidation of metabolic patterns of 7-azaindole-derived synthetic cannabinoids exemplified using cumyl-5F-P7AICA.
  • Nadja Walle
  • Frederike Nordmeier
  • Adrian A Doerr
  • Benjamin Peters
  • Matthias W Laschke
  • Michael D Menger
  • Peter H Schmidt
  • Markus R Meyer
  • Nadine Schaefer
  • Drug Test Anal.2020 Jul;doi: 10.1002/dta.2899.Epub 2020-07-17.

萎縮性紅斑性皮膚病変を呈する初期のライムボレリア症におけるアナプラズマ・ファゴサイトフィルムの存在の評価

Assessment of Anaplasma phagocytophilum presence in early Lyme borreliosis manifested by erythema migrans skin lesions.
  • Anna Moniuszko-Malinowska
  • Justyna Dunaj
  • Martin O Andersson
  • Piotr Czupryna
  • Joanna Zajkowska
  • Katarzyna Guziejko
  • Adam Garkowski
  • Sambor Grygorczuk
  • Maciej Kondrusik
  • Sławomir Pancewicz
  • Travel Med Infect Dis.2020 Apr;:101648. S1477-8939(18)30229-1. doi: 10.1016/j.tmaid.2020.101648.Epub 2020-04-01.

ヘモグロビン血症患者におけるCOVID-19の予備的データ。多施設共同ICET-A試験

Preliminary Data on COVID-19 in Patients with Hemoglobinopathies: A Multicentre ICET-A Study.
  • Vincenzo de Sanctis
  • Duran Canatan
  • Joan Lluis Vives Corrons
  • Mehran Karimi
  • Shahina Daar
  • Christos Kattamis
  • Ashraf T Soliman
  • Yasser Wali
  • Salam Alkindi
  • Valeh Huseynov
  • Afag Nasibova
  • Tarık Onur Tiryaki
  • Melike Sezgin Evim
  • Adalet Meral Gunes
  • Zeynep Karakas
  • Soteroula Christou
  • Saveria Campisi
  • Tahereh Zarei
  • Doaa Khater
  • Yesim Oymak
  • Valeriya Kaleva
  • Denka Stoyanova
  • Atanas Banchev
  • Maria Concetta Galati
  • Mohamed A Yassin
  • Shruti Kakar
  • Myrto Skafida
  • Yurdanur Kilinc
  • Saif Alyaarubi
  • Narmin Verdiyevas
  • Iva Stoeva
  • Giuseppe Raiola
  • Demetris Mariannis
  • Leopoldo Ruggiero
  • Salvatore Di Maio
  • Mediterr J Hematol Infect Dis.2020;12(1):e2020046. mjhid-12-1-e2020046. doi: 10.4084/MJHID.2020.046.Epub 2020-07-01.

インドにおける HBOC の遺伝カウンセリング、検査、および管理。インド医学・小児腫瘍学会による専門家のコンセンサス文書

Genetic Counseling, Testing, and Management of HBOC in India: An Expert Consensus Document from Indian Society of Medical and Pediatric Oncology.
  • Hemant Malhotra
  • Pradnya Kowtal
  • Nikita Mehra
  • Raja Pramank
  • Rajiv Sarin
  • Thangarajan Rajkumar
  • Sudeep Gupta
  • Ajay Bapna
  • Gouri Shankar Bhattacharyya
  • Sabhyata Gupta
  • Amita Maheshwari
  • Ashraf U Mannan
  • Ravindra Reddy Kundur
  • Rupinder Sekhon
  • Manish Singhal
  • B K Smruti
  • Somashekhar Sp
  • Moushumi Suryavanshi
  • Amit Verma
  • JCO Glob Oncol.2020 Jul;6:991-1008. doi: 10.1200/JGO.19.00381.

エノラーゼをコードする遺伝子 enoA の代替転写開始部位は、アスペルギルス・オリザエの解糖/ブドウ糖生成環境下で厳密に利用されていることが明らかになった

Alternative transcription start sites of the enolase-encoding gene enoA are stringently used in glycolytic/gluconeogenic conditions in Aspergillus oryzae.
  • Taishi Inoue
  • Hiroki Toji
  • Mizuki Tanaka
  • Mitsuru Takama
  • Sachiko Hasegawa-Shiro
  • Yuichi Yamaki
  • Takahiro Shintani
  • Katsuya Gomi
  • Curr. Genet..2020 Aug;66(4):729-747. 10.1007/s00294-020-01053-3. doi: 10.1007/s00294-020-01053-3.Epub 2020-02-18.

関節リウマチにおける生物学的医薬品の比較有効性：再解析された個々の患者データからの集計結果を含むシステマティックレビューおよびネットワークメタアナリシス

Comparative effectiveness of biological medicines in rheumatoid arthritis: systematic review and network meta-analysis including aggregate results from reanalysed individual patient data.
  • Kirsten Janke
  • Katharina Biester
  • Dietmar Krause
  • Bernd Richter
  • Christoph Schürmann
  • Katharina Hirsch
  • Helmut Hörn
  • Michaela Florina Kerekes
  • Petra Kohlepp
  • Beate Wieseler
  • BMJ.2020 07;370:m2288. doi: 10.1136/bmj.m2288.Epub 2020-07-07.

エーテル結合炭化水素鎖を含むリン脂質は、効率的なファゴサイトーシスに不可欠であり、エステル型の中性脂質は、細胞内での発達を妨げる

Phospholipids containing ether-bound hydrocarbon-chains are essential for efficient phagocytosis and neutral lipids of the ester-type perturb development in .
  • Frederik Kappelt
  • Xiaoli Du Ma
  • Bassam Abou Hasna
  • Jessica M Kornke
  • Markus Maniak
  • Biol Open.2020 Jul;9(7). bio052126. doi: 10.1242/bio.052126.Epub 2020-07-16.

COVID-19パンデミック時の糞便微生物移植サービスの再編成

Reorganisation of faecal microbiota transplant services during the COVID-19 pandemic.
  • Gianluca Ianiro
  • Benjamin H Mullish
  • Colleen R Kelly
  • Zain Kassam
  • Ed J Kuijper
  • Siew C Ng
  • Tariq H Iqbal
  • Jessica R Allegretti
  • Stefano Bibbò
  • Harry Sokol
  • Faming Zhang
  • Monika Fischer
  • Samuel Paul Costello
  • Josbert J Keller
  • Luca Masucci
  • Joffrey van Prehn
  • Gianluca Quaranta
  • Mohammed Nabil Quraishi
  • Jonathan Segal
  • Dina Kao
  • Reetta Satokari
  • Maurizio Sanguinetti
  • Herbert Tilg
  • Antonio Gasbarrini
  • Giovanni Cammarota
  • Gut.2020 Jul;gutjnl-2020-321829. doi: 10.1136/gutjnl-2020-321829.Epub 2020-07-03.

インド・プドゥチャリーの農村部と都市部における自殺念慮の有病率、自殺計画、自殺未遂とその関連因子

Prevalence of suicidal ideation, plan, attempts and its associated factors in selected rural and urban areas of Puducherry, India.
  • Aakanksha Singh
  • Ganesh Kumar Saya
  • Vikas Menon
  • Jeby Jose Olickal
  • Revathi Ulaganeethi
  • Roshina Sunny
  • Sadhana Subramanian
  • Ashutosh Kothari
  • Palanivel Chinnakali
  • J Public Health (Oxf).2020 Jul;fdaa101. doi: 10.1093/pubmed/fdaa101.Epub 2020-07-17.

プラズマ修飾バイオマス上での医薬品化合物や色素の除去プロセス機構の解明：吸着剤特異性の重要な役割

Insight into the removal process mechanism of pharmaceutical compounds and dyes on plasma-modified biomass: the key role of adsorbate specificity.
  • Brice Takam
  • Jean-Baptiste Tarkwa
  • Elie Acayanka
  • Serge Nzali
  • Darryle M Chesseu
  • Georges Y Kamgang
  • Samuel Laminsi
  • Environ Sci Pollut Res Int.2020 Jun;27(16):20500-20515. 10.1007/s11356-020-08536-3. doi: 10.1007/s11356-020-08536-3.Epub 2020-04-03.

出血しやすい心臓手術患者における超音波ガイド下腋窩静脈カテーテル検査（PANDA）の近位アプローチと遠位アプローチの比較：無作為化比較試験

Comparison of the proximal and distal approaches for axillary vein catheterization under ultrasound guidance (PANDA) in cardiac surgery patients susceptible to bleeding: a randomized controlled trial.
  • Ying Su
  • Jun-Yi Hou
  • Guo-Guang Ma
  • Guang-Wei Hao
  • Jing-Chao Luo
  • Shen-Ji Yu
  • Kai Liu
  • Ji-Li Zheng
  • Yan Xue
  • Zhe Luo
  • Guo-Wei Tu
  • Ann Intensive Care.2020 Jul;10(1):90. 10.1186/s13613-020-00703-6. doi: 10.1186/s13613-020-00703-6.Epub 2020-07-08.

潰瘍性大腸炎における大腸新生物に対する Colectomies の傾向：2 年間の全国入院患者サンプルのデータベース解析

Trends in Colectomies for Colorectal Neoplasms in Ulcerative Colitis: a National Inpatient Sample Database Analysis over Two Decades.
  • Alexander Ni
  • Mohammed Al-Qahtani
  • Ebram Salama
  • Daniel Marinescu
  • Maria Abou Khalil
  • Julio Faria
  • Nancy Morin
  • Gabriela Ghitulescu
  • Carol-Ann Vasilevsky
  • Marylise Boutros
  • J. Gastrointest. Surg..2020 Jun;10.1007/s11605-020-04666-8. doi: 10.1007/s11605-020-04666-8.Epub 2020-06-15.

病理組織標本中のアミロイド蛋白質の質量分析法による絶対定量。そのメリットと限界

Mass spectrometry-based absolute quantification of amyloid proteins in pathology tissue specimens: Merits and limitations.
  • Makiko Ogawa
  • Yukako Shintani-Domoto
  • Yoshiki Nagashima
  • Koji L Ode
  • Aya Sato
  • Yoshihiro Shimizu
  • Kenichi Ohashi
  • Michael H A Roehrl
  • Tetsuo Ushiku
  • Hiroki R Ueda
  • Masashi Fukayama
  • PLoS ONE.2020;15(7):e0235143. PONE-D-20-02311. doi: 10.1371/journal.pone.0235143.Epub 2020-07-01.

全身麻酔下での障害者の歯科治療において、術前歯科検診は不必要な抜歯を予防する可能性がある-レトロスペクティブ横断的研究の結果

Preoperative Dental Examination Might Prevent Unnecessary Tooth Extractions During Dental Treatment of Patients with Disabilities Under General Anaesthesia - Results of a Retrospective Cross-Sectional Study.
  • Gerhard Schmalz
  • Mathias Farack
  • Tanja Kottmann
  • Jana Schmidt
  • Felix Krause
  • Dirk Ziebolz
  • Oral Health Prev Dent.2020;18(2):139-144. 43364. doi: 10.3290/j.ohpd.a43364.

ホスホリパーゼCゼータ分析を用いた人工卵子活性化の候補者の同定：臨床妊娠例と患者管理のためのアルゴリズムの提案

Use of phospholipase C zeta analysis to identify candidates for artificial oocyte activation: a case series of clinical pregnancies and a proposed algorithm for patient management.
  • Xin Meng
  • Pedro Melo
  • Celine Jones
  • Caroline Ross
  • Ginny Mounce
  • Karen Turner
  • Tim Child
  • Kevin Coward
  • Fertil. Steril..2020 Jul;114(1):163-174. S0015-0282(20)30243-0. doi: 10.1016/j.fertnstert.2020.02.113.

本研究では、調理方法がイネ科魚類からのパーフルオロアルキル物質およびポリフルオロアルキル物質（PFAS）の摂取量に影響を与えることを明らかにした

Cooking methods affect the intake of per- and polyfluoroalkyl substances (PFASs) from grass carp.
  • Yuning Hu
  • Cuiyun Wei
  • Ling Wang
  • Zhen Zhou
  • Thanh Wang
  • Guangliang Liu
  • Yuqi Feng
  • Yong Liang
  • Ecotoxicol. Environ. Saf..2020 Jul;203:111003. S0147-6513(20)30842-3. doi: 10.1016/j.ecoenv.2020.111003.Epub 2020-07-14.

腎細胞癌に対する腎切除術後の腎機能と生存率に及ぼす温熱虚血時間の短さの影響：多施設共同傾向スコアマッチ試験

Impact of short warm ischemic time on longitudinal kidney function and survival rate after partial nephrectomy for renal cell carcinoma in patients with pre-existing chronic kidney disease stage III: A multi-institutional propensity score-matched study.
  • Jae-Seung Chung
  • Sung Kyu Hong
  • Sang Chul Lee
  • Chang Wook Jeong
  • Cheol Kwak
  • Hyeon Hoe Kim
  • Sung Hoo Hong
  • Yong June Kim
  • Seok Ho Kang
  • Jinsoo Chung
  • Tae Gyun Kwon
  • Eu Chang Hwang
  • Seok-Soo Byun
  • Eur J Surg Oncol.2020 Jun;S0748-7983(20)30540-0. doi: 10.1016/j.ejso.2020.06.016.Epub 2020-06-17.

心原毒素誘発性骨格筋損傷は、同化およびストレスシグナル伝達、および筋繊維タイプの構成における深遠な変化を誘発する

Cardiotoxin-induced skeletal muscle injury elicits profound changes in anabolic and stress signaling, and muscle fiber type composition.
  • Sebastiaan Dalle
  • Charlotte Hiroux
  • Chiel Poffé
  • Monique Ramaekers
  • Louise Deldicque
  • Katrien Koppo
  • J. Muscle Res. Cell. Motil..2020 Jul;10.1007/s10974-020-09584-5. doi: 10.1007/s10974-020-09584-5.Epub 2020-07-03.

乾燥性湿疹が出やすい肌の人を対象とした、セラミドをマルチベシキュラー乳液に配合したクリームと化粧水の肌バリア修復効果の検討。RESTORE試験フェーズ1

An Investigation of the Skin Barrier Restoring Effects of a Cream and Lotion Containing Ceramides in a Multi-vesicular Emulsion in People with Dry, Eczema-Prone, Skin: The RESTORE Study Phase 1.
  • Simon G Danby
  • Paul V Andrew
  • Kirsty Brown
  • John Chittock
  • Linda J Kay
  • Michael J Cork
  • Dermatol Ther (Heidelb).2020 Jul;10.1007/s13555-020-00426-3. doi: 10.1007/s13555-020-00426-3.Epub 2020-07-15.

この研究では、熱帯東太平洋の生物多様性のホットスポットに生息する小型海綿エビ（デカポダ: Palaemonidae）に対応するために、新しいパラエモンエビ属を設立した

Unesconia coibensis, gen. et sp. nov., a miniature sponge-associated shrimp from a biodiversity hotspot in the tropical eastern Pacific (Decapoda: Palaemonidae).
  • Arthur Anker
  • Zootaxa.2020 Feb;4731(1):zootaxa.4731.1.8. zootaxa.4731.1.8. doi: 10.11646/zootaxa.4731.1.8.Epub 2020-02-04.

治療抵抗性精神病における治療開始および維持のための筋肉内クロザピン処方のレトロスペクティブ研究

A retrospective study of intramuscular clozapine prescription for treatment initiation and maintenance in treatment-resistant psychosis.
  • Cecilia Casetta
  • Ebenezer Oloyede
  • Eromona Whiskey
  • David Michael Taylor
  • Fiona Gaughran
  • Sukhi S Shergill
  • Juliana Onwumere
  • Aviv Segev
  • Olubanke Dzahini
  • Sophie E Legge
  • James Hunter MacCabe
  • Br J Psychiatry.2020 Jul;:1-8. S0007125020001154. doi: 10.1192/bjp.2020.115.Epub 2020-07-01.

豚の大動脈弁に対する非侵襲的超音波治療（NIUT）の可能性と安全性

Feasibility and safety of non-invasive ultrasound therapy (NIUT) on porcine aortic valve.
  • Emmanuel Messas
  • Mathieu Cyril Rémond
  • Guillaume Goudot
  • Samuel Zarka
  • Robin Penot
  • Philippe Mateo
  • Wojciech Kwiecinski
  • Daniel Suarez Escudero
  • Alain Bel
  • Nathalie Ialy-Radio
  • Benjamin Bertrand
  • Patrick Bruneval
  • Eloi Marijon
  • René Spaargaren
  • Mickael Tanter
  • Mathieu Pernot
  • Phys Med Biol.2020 Jul;doi: 10.1088/1361-6560/aba6d3.Epub 2020-07-16.

L1CAM, CA9, KLK6, HPN, ALDH1A1の3つの血清バイオマーカーは、原発性および転移性大腸がんのスクリーニングにおける潜在的な血清マーカーであることが示された

L1CAM, CA9, KLK6, HPN, and ALDH1A1 as Potential Serum Markers in Primary and Metastatic Colorectal Cancer Screening.
  • Francis Yew Fu Tieng
  • Nadiah Abu
  • Surani Sukor
  • Zairul Azwan Mohd Azman
  • Norshahidah Mahamad Nadzir
  • Learn-Han Lee
  • Nurul Syakima Ab Mutalib
  • Diagnostics (Basel).2020 Jun;10(7). E444. doi: 10.3390/diagnostics10070444.Epub 2020-06-30.

パルス電磁場は骨間葉系幹細胞の骨形成分化過程でmiRNAを調節する：骨形成-血管形成カップリングにおける可能性のある役割

Pulsed Electromagnetic Fields Modulate miRNAs During Osteogenic Differentiation of Bone Mesenchymal Stem Cells: a Possible Role in the Osteogenic-angiogenic Coupling.
  • Monica De Mattei
  • Silvia Grassilli
  • Agnese Pellati
  • Federica Brugnoli
  • Elena De Marchi
  • Deyanira Contartese
  • Valeria Bertagnolo
  • Stem Cell Rev Rep.2020 Jul;10.1007/s12015-020-10009-6. doi: 10.1007/s12015-020-10009-6.Epub 2020-07-18.

根治的前立腺摘除術後の結節再発前立腺がんに対するサルベージリンパ節郭清の長期成績：これまで考えられていたほどではない

Long-term Outcomes of Salvage Lymph Node Dissection for Nodal Recurrence of Prostate Cancer After Radical Prostatectomy: Not as Good as Previously Thought.
  • Carlo A Bravi
  • Nicola Fossati
  • Giorgio Gandaglia
  • Nazareno Suardi
  • Elio Mazzone
  • Daniele Robesti
  • Daniar Osmonov
  • Klaus-Peter Juenemann
  • Luca Boeri
  • R Jeffrey Karnes
  • Alexander Kretschmer
  • Alexander Buchner
  • Christian Stief
  • Andreas Hiester
  • Alessandro Nini
  • Peter Albers
  • Gaëtan Devos
  • Steven Joniau
  • Hendrik Van Poppel
  • Shahrokh F Shariat
  • Axel Heidenreich
  • David Pfister
  • Derya Tilki
  • Markus Graefen
  • Inderbir S Gill
  • Alexander Mottrie
  • Pierre I Karakiewicz
  • Francesco Montorsi
  • Alberto Briganti
  • Eur. Urol..2020 Jul;S0302-2838(20)30472-3. doi: 10.1016/j.eururo.2020.06.043.Epub 2020-07-02.

中等度薬剤耐性Y株（DTU TcII）に対する2種類の5-ニトロインダゾール誘導体の活性プロファイル：および研究

Activity profile of two 5-nitroindazole derivatives over the moderately drug-resistant Y strain (DTU TcII): and studies.
  • Cristina Fonseca-Berzal
  • Cristiane França da Silva
  • Denise da Gama Jaen Batista
  • Gabriel Melo de Oliveira
  • José Cumella
  • Marcos Meuser Batista
  • Raiza Brandão Peres
  • Aline Silva da Gama Nefertiti
  • José A Escario
  • Alicia Gómez-Barrio
  • Vicente J Arán
  • Maria de Nazaré Correia Soeiro
  • Parasitology.2020 Jun;:1-13. S0031182020000955. doi: 10.1017/S0031182020000955.Epub 2020-06-12.

インドの肝斑患者におけるアジュバントとしての経口トラネキサム酸の有効性と安全性：プロスペクティブ、インターベンショナル、単施設、三重盲検、無作為化、プラセボ対照、並行群間試験

Efficacy and safety of oral tranexamic acid as an adjuvant in Indian patients with melasma: a prospective, interventional, single-centre, triple-blind, randomized, placebo-control, parallel group study.
  • K Minni
  • S Poojary
  • J Eur Acad Dermatol Venereol.2020 Jun;:e16598. doi: 10.1111/jdv.16598.Epub 2020-06-22.

改良されたデュアルAAVベクターを用いて発現を抑制し、スターガルト病モデルマウスの網膜に安全かつ効果的に発現させることができた

Improved dual AAV vectors with reduced expression of truncated proteins are safe and effective in the retina of a mouse model of Stargardt disease.
  • Ivana Trapani
  • Elisabetta Toriello
  • Sonia de Simone
  • Pasqualina Colella
  • Carolina Iodice
  • Elena V Polishchuk
  • Andrea Sommella
  • Linda Colecchi
  • Settimio Rossi
  • Francesca Simonelli
  • Massimo Giunti
  • Maria L Bacci
  • Roman S Polishchuk
  • Alberto Auricchio
  • Hum. Mol. Genet..2015 Dec;24(23):6811-25. ddv386. doi: 10.1093/hmg/ddv386.Epub 2015-09-29.

新規チエノ2,3-ピリジン系抗がん剤治療後の乳がん幹細胞におけるグリコスフィンゴ脂質発現の解析

Glycosphingolipid expression at breast cancer stem cells after novel thieno[2,3-b]pyridine anticancer compound treatment.
  • Sandra Marijan
  • Anita Markotić
  • Angela Mastelić
  • Nikolina Režić-Mužinić
  • Lisa Ivy Pilkington
  • Johannes Reynisson
  • Vedrana Čikeš Čulić
  • Sci Rep.2020 Jul;10(1):11876. 10.1038/s41598-020-68516-y. doi: 10.1038/s41598-020-68516-y.Epub 2020-07-17.

小児脳外科手術における視神経放射線トラクトグラフィの応用．トラクトグラフィ法の信頼性と一致性の評価

Optic Radiation Tractography in Pediatric Brain Surgery Applications: A Reliability and Agreement Assessment of the Tractography Method.
  • Joseph Yuan-Mou Yang
  • Richard Beare
  • Michelle Hao Wu
  • Sarah M Barton
  • Charles B Malpas
  • Chun-Hung Yeh
  • A Simon Harvey
  • Vicki Anderson
  • Wirginia J Maixner
  • Marc Seal
  • Front Neurosci.2019;13:1254. doi: 10.3389/fnins.2019.01254.Epub 2019-11-20.

ヌクレオラ RNA ポリメラーゼ II はリボソームの生合成を駆動している

Nucleolar RNA polymerase II drives ribosome biogenesis.
  • Karan J Abraham
  • Negin Khosraviani
  • Janet N Y Chan
  • Aparna Gorthi
  • Anas Samman
  • Dorothy Y Zhao
  • Miling Wang
  • Michael Bokros
  • Elva Vidya
  • Lauren A Ostrowski
  • Roxanne Oshidari
  • Violena Pietrobon
  • Parasvi S Patel
  • Arash Algouneh
  • Rajat Singhania
  • Yupeng Liu
  • V Talya Yerlici
  • Daniel D De Carvalho
  • Michael Ohh
  • Brendan C Dickson
  • Razq Hakem
  • Jack F Greenblatt
  • Stephen Lee
  • Alexander J R Bishop
  • Karim Mekhail
  • Nature.2020 Jul;10.1038/s41586-020-2497-0. doi: 10.1038/s41586-020-2497-0.Epub 2020-07-15.

デオキシコラート中での増殖のプロテオミクスにより、野生型ヒト感染表現型に必要なシスチン輸送タンパク質としてのCj0025cが明らかになった

Proteomics of growth in deoxycholate reveals Cj0025c as a cystine transport protein required for wild-type human infection phenotypes.
  • Lok Man
  • Ashleigh L Dale
  • William P Klare
  • Joel A Cain
  • Zeynep Sumer-Bayraktar
  • Paula Niewold
  • Nestor Solis
  • Stuart J Cordwell
  • Mol. Cell Proteomics.2020 May;mcp.RA120.002029. doi: 10.1074/mcp.RA120.002029.Epub 2020-05-06.

イタリア，ロンバルディア州の集中治療室における COVID-19 患者の死亡率に関連する危険因子

Risk Factors Associated With Mortality Among Patients With COVID-19 in Intensive Care Units in Lombardy, Italy.
  • Giacomo Grasselli
  • Massimiliano Greco
  • Alberto Zanella
  • Giovanni Albano
  • Massimo Antonelli
  • Giacomo Bellani
  • Ezio Bonanomi
  • Luca Cabrini
  • Eleonora Carlesso
  • Gianpaolo Castelli
  • Sergio Cattaneo
  • Danilo Cereda
  • Sergio Colombo
  • Antonio Coluccello
  • Giuseppe Crescini
  • Andrea Forastieri Molinari
  • Giuseppe Foti
  • Roberto Fumagalli
  • Giorgio Antonio Iotti
  • Thomas Langer
  • Nicola Latronico
  • Ferdinando Luca Lorini
  • Francesco Mojoli
  • Giuseppe Natalini
  • Carla Maria Pessina
  • Vito Marco Ranieri
  • Roberto Rech
  • Luigia Scudeller
  • Antonio Rosano
  • Enrico Storti
  • B Taylor Thompson
  • Marcello Tirani
  • Pier Giorgio Villani
  • Antonio Pesenti
  • Maurizio Cecconi
  • JAMA Intern Med.2020 Jul;2768601. doi: 10.1001/jamainternmed.2020.3539.Epub 2020-07-15.

粘液捕食を行うRuminococcus gnavusのシアル酸代謝経路の解明により、細菌の腸内適応機構が解明された

Elucidation of a sialic acid metabolism pathway in mucus-foraging Ruminococcus gnavus unravels mechanisms of bacterial adaptation to the gut.
  • Andrew Bell
  • Jason Brunt
  • Emmanuelle Crost
  • Laura Vaux
  • Ridvan Nepravishta
  • C David Owen
  • Dimitrios Latousakis
  • An Xiao
  • Wanqing Li
  • Xi Chen
  • Martin A Walsh
  • Jan Claesen
  • Jesus Angulo
  • Gavin H Thomas
  • Nathalie Juge
  • Nat Microbiol.2019 12;4(12):2393-2404. 10.1038/s41564-019-0590-7. doi: 10.1038/s41564-019-0590-7.Epub 2019-10-21.

腹腔鏡下ロボット支援根治的前立腺摘出術における括約筋下吻合術（SSA）と、それが大陸の回復に与えるポジティブな影響

Sub-sphincteric anastomosis (SSA) during laparoscopic robotic-assisted radical prostatectomy and its positive impact on continence recovery.
  • Christophe Almeras
  • Christophe Tollon
  • Ambroise Salin
  • Jean-Baptiste Beauval
  • Guillaume Loison
  • Jean Romain Gautier
  • Guillaume Ploussard
  • J. Endourol..2020 Jul;doi: 10.1089/end.2020.0379.Epub 2020-07-16.

食餌性抗生物質への慢性的な曝露は腸の健康に影響を与え、抗生物質耐性遺伝子の豊富さに影響を与え、ヒトの健康リスクを誘発する

Chronic exposure to dietary antibiotics affects intestinal health and antibiotic resistance gene abundance in oriental river prawn (Macrobrachium nipponense), and provokes human health risk.
  • Shengming Sun
  • Dominic K A Korheina
  • Hongtuo Fu
  • Xianping Ge
  • Sci. Total Environ..2020 Jun;720:137478. S0048-9697(20)30989-X. doi: 10.1016/j.scitotenv.2020.137478.Epub 2020-02-21.

2成分ポリマー半導体システムのマイクロ流体印刷のためのミックスフロー設計

Mixed-flow design for microfluidic printing of two-component polymer semiconductor systems.
  • Gang Wang
  • Liang-Wen Feng
  • Wei Huang
  • Subhrangsu Mukherjee
  • Yao Chen
  • Dengke Shen
  • Binghao Wang
  • Joseph Strzalka
  • Ding Zheng
  • Ferdinand S Melkonyan
  • Jinhui Yan
  • J Fraser Stoddart
  • Simone Fabiano
  • Dean M DeLongchamp
  • Meifang Zhu
  • Antonio Facchetti
  • Tobin J Marks
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外傷性脳損傷後6ヶ月間の疲労の頻度とその変化：CENTER-TBI試験の結果

Frequency of fatigue and its changes in the first 6 months after traumatic brain injury: results from the CENTER-TBI study.
  • Nada Andelic
  • Cecilie Røe
  • Cathrine Brunborg
  • Marina Zeldovich
  • Marianne Løvstad
  • Daniel Løke
  • Ida M Borgen
  • Daphne C Voormolen
  • Emilie I Howe
  • Marit V Forslund
  • Hilde M Dahl
  • Nicole von Steinbuechel
  • J. Neurol..2020 Jul;10.1007/s00415-020-10022-2. doi: 10.1007/s00415-020-10022-2.Epub 2020-07-16.

癌特異的炭酸脱水酵素IXの高選択的阻害剤としてのスルホンアミドカルボランの開発

Sulfonamido carboranes as highly selective inhibitors of cancer-specific carbonic anhydrase IX.
  • Jana Dvořanová
  • Michael Kugler
  • Josef Holub
  • Václav Šícha
  • Viswanath Das
  • Jan Nekvinda
  • Suzan El Anwar
  • Miroslav Havránek
  • Klára Pospíšilová
  • Milan Fábry
  • Vlastimil Král
  • Martina Medvedíková
  • Stanislava Matějková
  • Barbora Lišková
  • Soňa Gurská
  • Petr Džubák
  • Jiří Brynda
  • Marián Hajdúch
  • Bohumír Grüner
  • Pavlína Řezáčová
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フランス領ポリネシアにおける感染性心内膜炎：疫学、治療および転帰

Infective endocarditis in French Polynesia: Epidemiology, treatments and outcomes.
  • Virginie Blanchard
  • Bruno Pagis
  • Rainui Richaud
  • Fréderic Moronval
  • Renaud Lutinier
  • Katell Gallais
  • Christophe Le Goanvic
  • Anthony Fontan
  • Sylvain Girardot
  • Florence Ah-Kang
  • Olivier Atger
  • Bernard Iung
  • Yoan Lavie-Badie
  • Arch Cardiovasc Dis.2020 Apr;113(4):252-262. S1875-2136(20)30032-2. doi: 10.1016/j.acvd.2019.12.007.Epub 2020-02-15.

隠れた多様性の発見：形態学的検討とミトコンドリア遺伝子解析で明らかにした新種のブラジル新熱帯地域産淡水エビ（Decapoda: Caridea: Palaemonidae）

Uncovering a hidden diversity: a new species of freshwater shrimp Macrobrachium (Decapoda: Caridea: Palaemonidae) from Neotropical region (Brazil) revealed by morphological review and mitochondrial genes analyses.
  • Natalia Rossi
  • Célio Magalhães
  • Elis R Mesquita
  • Fernando L Mantelatto
  • Zootaxa.2020 Feb;4732(1):zootaxa.4732.1.9. zootaxa.4732.1.9. doi: 10.11646/zootaxa.4732.1.9.Epub 2020-02-11.

レーザー末梢血管切開術後の0.1％ネパフェナックと1％酢酸プレドニゾロン点眼薬の安全性と有効性。A Prospective, Randomized Trial

Safety and Efficacy of 0.1% Nepafenac versus 1% Prednisolone Acetate Eye Drops after Laser Peripheral Iridotomy: A Prospective, Randomized Trial.
  • Keerthi Gayam
  • Pradeep Y Ramulu
  • Venkatesh Rengaraj
  • Kavitha Srinivasan
  • Ophthalmol Glaucoma.2020 May - Jun;3(3):174-180. S2589-4196(20)30051-X. doi: 10.1016/j.ogla.2020.02.006.Epub 2020-02-29.

ゲノムワイドなプロファイリングにより、エネルギー代謝の変化に関連したロッド型光受容体の老化のDNAメチル化シグネチャーを同定した

Genome-wide Profiling Identifies DNA Methylation Signatures of Aging in Rod Photoreceptors Associated with Alterations in Energy Metabolism.
  • Ximena Corso-Díaz
  • James Gentry
  • Ryan Rebernick
  • Catherine Jaeger
  • Matthew J Brooks
  • Freekje van Asten
  • Keshav Kooragayala
  • Linn Gieser
  • Jacob Nellissery
  • Raul Covian
  • Tiziana Cogliati
  • Anupam K Mondal
  • Ke Jiang
  • Anand Swaroop
  • Cell Rep.2020 Apr;31(3):107525. S2211-1247(20)30425-3. doi: 10.1016/j.celrep.2020.107525.

HDAC1、HDAC6およびHDAC8の阻害剤としてのヒドロキサム酸誘導体は、癌細胞株において抗増殖活性を有する

Hydroxamic acid derivatives as HDAC1, HDAC6 and HDAC8 inhibitors with antiproliferative activity in cancer cell lines.
  • Yudibeth Sixto-López
  • José Antonio Gómez-Vidal
  • Nuria de Pedro
  • Martiniano Bello
  • Martha Cecilia Rosales-Hernández
  • José Correa-Basurto
  • Sci Rep.2020 Jun;10(1):10462. 10.1038/s41598-020-67112-4. doi: 10.1038/s41598-020-67112-4.Epub 2020-06-26.

COVID-19 感染が確認された 61,742 例の COVID-19 患者の臨床的特徴、検査所見、X 線写真徴候、転帰。システマティックレビューおよびメタアナリシス

Clinical characteristics, laboratory findings, radiographic signs and outcomes of 61,742 patients with confirmed COVID-19 infection: A systematic review and meta-analysis.
  • Ali Pormohammad
  • Saied Ghorbani
  • Behzad Baradaran
  • Alireza Khatami
  • Raymond Turner
  • Mohammad Ali Mansournia
  • Demetrios N Kyriacou
  • Juan-Pablo Idrovo
  • Nathan C Bahr
  • Microb. Pathog..2020 Jul;:104390. S0882-4010(20)30756-7. doi: 10.1016/j.micpath.2020.104390.Epub 2020-07-15.

パラミクソウイルスポリメラーゼの経口的に有効な広汎なアロステリック阻害剤

Orally efficacious broad-spectrum allosteric inhibitor of paramyxovirus polymerase.
  • Robert M Cox
  • Julien Sourimant
  • Mart Toots
  • Jeong-Joong Yoon
  • Satoshi Ikegame
  • Mugunthan Govindarajan
  • Ruth E Watkinson
  • Patricia Thibault
  • Negar Makhsous
  • Michelle J Lin
  • Jose R Marengo
  • Zachary Sticher
  • Alexander A Kolykhalov
  • Michael G Natchus
  • Alexander L Greninger
  • Benhur Lee
  • Richard K Plemper
  • Nat Microbiol.2020 Jul;10.1038/s41564-020-0752-7. doi: 10.1038/s41564-020-0752-7.Epub 2020-07-13.

脂肪由来幹細胞からの細胞外小胞は、活性酸素種の産生と炎症を減衰させることにより、紫外線B誘発性皮膚光老化を改善する

Extracellular vesicles from adipose-derived stem cells ameliorate ultraviolet B-induced skin photoaging by attenuating reactive oxygen species production and inflammation.
  • Peng Xu
  • Yu Xin
  • Zheng Zhang
  • Xiangyu Zou
  • Ke Xue
  • Huizhong Zhang
  • Wenjie Zhang
  • Kai Liu
  • Stem Cell Res Ther.2020 Jul;11(1):264. 10.1186/s13287-020-01777-6. doi: 10.1186/s13287-020-01777-6.Epub 2020-07-01.

炭酸塩岩の流動挙動に及ぼす細孔径分布の影響に関する考察.ナノベースの油分回収技術と岩石のタイピングを結びつける

Insights into the Effects of Pore Size Distribution on the Flowing Behavior of Carbonate Rocks: Linking a Nano-Based Enhanced Oil Recovery Method to Rock Typing.
  • Amin Rezaei
  • Hadi Abdollahi
  • Zeinab Derikvand
  • Abdolhossein Hemmati-Sarapardeh
  • Amir Mosavi
  • Narjes Nabipour
  • Nanomaterials (Basel).2020 May;10(5). E972. doi: 10.3390/nano10050972.Epub 2020-05-18.