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日本語AIでPubMedを検索

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日本語AIでPubMedを検索

PubMedの提供する医学論文データベースを日本語で検索できます。AI(Deep Learning)を活用した機械翻訳エンジンにより、精度高く日本語へ翻訳された論文をご参照いただけます。
対象期間    ～ 

2020年07月 みんなが読んでいる論文

ペクチン修飾FeO NP上にPd NPを作製した。磁性ナノ触媒を用いたC-CおよびC-Nクロスカップリング反応と心血管保護効果の検討

Fabrication of Pd NPs on pectin-modified FeO NPs: A magnetically nanocatalyst for C-C and C-N cross coupling reactions and investigating the cardiovascular protective effects.
  • Wei Zhang
  • Hojat Veisi
  • Reyhaneh Sharifi
  • Delafarin Salamat
  • Bikash Karmakar
  • Malak Hekmati
  • Saba Hemmati
  • Zhiyong Zhang
  • Qiang Su
  • Mohammad Mahdi Zangeneh
  • Int. J. Biol. Macromol..2020 May;S0141-8130(20)33416-4. doi: 10.1016/j.ijbiomac.2020.05.247.Epub 2020-05-30.

多嚢胞性卵巣症候群-痰湿潤症候群のインスリン抵抗性を持つ不妊患者の卵巣顆粒膜細胞におけるIRS-1/PI3K/GLUT4経路の発現に対する電気鍼治療の効果

Effect of Electro-acupuncture on Expression of IRS-1/PI3K/GLUT4 Pathway in Ovarian Granulosa Cells of Infertile Patients with Polycystic Ovary Syndrome-Insulin Resistance of Phlegm-Dampness Syndrome.
  • Shan Xiang
  • Ming-Feng Xia
  • Jing-Yan Song
  • Dan-Qi Liu
  • Fang Lian
  • Chin J Integr Med.2020 Jun;10.1007/s11655-020-3219-z. doi: 10.1007/s11655-020-3219-z.Epub 2020-06-22.

血管周囲幹細胞由来シクロフィリンAはHIF1α依存性血管新生を介してアッシャーマン症候群の子宮環境を改善する

Perivascular Stem Cell-Derived Cyclophilin A Improves Uterine Environment with Asherman's Syndrome via HIF1α-Dependent Angiogenesis.
  • Mira Park
  • Seok-Ho Hong
  • So Hee Park
  • Yeon Sun Kim
  • Seung Chel Yang
  • Hye-Ryun Kim
  • Songmi Noh
  • Sunghun Na
  • Hyung Keun Lee
  • Hyunjung J Lim
  • Sang Woo Lyu
  • Haengseok Song
  • Mol. Ther..2020 May;S1525-0016(20)30249-5. doi: 10.1016/j.ymthe.2020.05.015.Epub 2020-05-20.

新生児集中治療室における抗菌薬の投与。臨床実践は薬物動態学に基づく推奨事項を反映しているか？

Dosing of Antimicrobials in the Neonatal Intensive Care Unit: Does Clinical Practice Reflect Pharmacokinetics-based Recommendations?
  • Ashley Stark
  • Julie Childers
  • Morgan England
  • Reese H Clark
  • Matthew Laughon
  • Michael Cohen-Wolkowiez
  • Daniel K Benjamin
  • P Brian Smith
  • Kelly Wade
  • Rachel G Greenberg
  • Pediatr. Infect. Dis. J..2020 Aug;39(8):713-717. 00006454-202008000-00014. doi: 10.1097/INF.0000000000002657.

FMRPを欠損したヒト多能性幹細胞由来の皮質神経細胞は、自然発火パターンの変化を示す

Cortical neurons derived from human pluripotent stem cells lacking FMRP display altered spontaneous firing patterns.
  • Shreya Das Sharma
  • Rakhi Pal
  • Bharath Kumar Reddy
  • Bhuvaneish T Selvaraj
  • Nisha Raj
  • Krishna Kumar Samaga
  • Durga J Srinivasan
  • Loren Ornelas
  • Dhruv Sareen
  • Matthew R Livesey
  • Gary J Bassell
  • Clive N Svendsen
  • Peter C Kind
  • Siddharthan Chandran
  • Sumantra Chattarji
  • David J A Wyllie
  • Mol Autism.2020 Jun;11(1):52. 10.1186/s13229-020-00351-4. doi: 10.1186/s13229-020-00351-4.Epub 2020-06-19.

慢性ストレスと咬合不安定性によって誘発される咀嚼筋機能障害に対するベンゾジアゼピンの有益な効果を動物実験で明らかにした

Beneficial effects of benzodiazepine on masticatory muscle dysfunction induced by chronic stress and occlusal instability in an experimental animal study.
  • Glauce C Nascimento
  • Bruno L Malzone
  • Daniela M Iyomasa
  • Yamba C L Pereira
  • João Paulo M Issa
  • Christie R A Leite-Panissi
  • Ii-Sei Watanabe
  • Mamie M Iyomasa
  • Ramon Fuentes
  • Elaine Del Bel
  • Fernando J Dias
  • Sci Rep.2020 May;10(1):8787. 10.1038/s41598-020-65524-w. doi: 10.1038/s41598-020-65524-w.Epub 2020-05-29.

臨床血圧測定のオブザーバーのパフォーマンスの最適化: Lancet Commission on Hypertension Groupからのポジションステートメント動脈圧測定におけるオブザーバーのパフォーマンスの最適化: Posicionamento do Grupo da

[Optimizing observer performance of clinic blood Pressure measurement: a position statement from the Lancet Commission on Hypertension GroupOtimização do desempenho do observador na medição clínica da pressão arterial: posicionamento do Grupo da ].
  • Raj Padwal
  • Norm R C Campbell
  • Aletta E Schutte
  • Michael Hecht Olsen
  • Christian Delles
  • Anthony Etyang
  • J Kennedy Cruickshank
  • George Stergiou
  • Michael K Rakotz
  • Gregory Wozniak
  • Marc G Jaffe
  • Ivor Benjamin
  • Gianfranco Parati
  • James E Sharman
  • Rev. Panam. Salud Publica.2020;44:e88. RPSP.2020.88. doi: 10.26633/RPSP.2020.88.Epub 2020-07-15.

網膜眼底写真における糖尿病性網膜症の検出のためのディープラーニングアルゴリズム。システマティックレビューとメタアナリシス

Deep learning algorithms for detection of diabetic retinopathy in retinal fundus photographs: A systematic review and meta-analysis.
  • Md Mohaimenul Islam
  • Hsuan-Chia Yang
  • Tahmina Nasrin Poly
  • Wen-Shan Jian
  • Yu-Chuan Jack Li
  • Comput Methods Programs Biomed.2020 Jul;191:105320. S0169-2607(19)31101-0. doi: 10.1016/j.cmpb.2020.105320.Epub 2020-01-16.

前立腺肥大症に対するホルミウムレーザーによる前立腺の核出術と経尿道的前立腺切除術との間の前立腺癌の診断価値：レトロスペクティブな比較研究

The diagnostic value of prostate cancer between holmium laser enucleation of the prostate and transurethral resection of the prostate for benign prostatic hyperplasia: A retrospective comparative study.
  • Gaofei He
  • Chengfang Sun
  • Yuanyuan Shu
  • Bohan Wang
  • Chuanjun Du
  • Jimin Chen
  • Jiaming Wen
  • Int J Surg.2020 Jul;79:217-221. S1743-9191(20)30408-8. doi: 10.1016/j.ijsu.2020.05.025.Epub 2020-05-21.

RGS4はPGE2生合成を阻害することで、アレルゲンやアスピリンに関連した気道過敏反応性を促進する

RGS4 promotes allergen- and aspirin-associated airway hyperresponsiveness by inhibiting PGE2 biosynthesis.
  • Gordon S Wong
  • Jamie L Redes
  • Nariman Balenga
  • Morgan McCullough
  • Nathalie Fuentes
  • Ameya Gokhale
  • Cynthia Koziol-White
  • Joseph A Jude
  • Laura A Madigan
  • Eunice C Chan
  • William H Jester
  • Sabrina Biardel
  • Nicolas Flamand
  • Reynold A Panettieri
  • Kirk M Druey
  • J. Allergy Clin. Immunol..2020 Mar;S0091-6749(20)30372-9. doi: 10.1016/j.jaci.2020.03.004.Epub 2020-03-19.

組換えアディポネクチンペプチドは、Smad3 シグナル阻害を介して糖尿病マウスのミトコンドリアおよび ATF4-CHOP アポトーシス経路を抑制し、脳内出血後の神経細胞の生存を促進する

Recombinant adiponectin peptide promotes neuronal survival after intracerebral haemorrhage by suppressing mitochondrial and ATF4-CHOP apoptosis pathways in diabetic mice via Smad3 signalling inhibition.
  • Xun Wu
  • Jianing Luo
  • Haixiao Liu
  • Wenxing Cui
  • Wei Guo
  • Lei Zhao
  • Hao Guo
  • Hao Bai
  • Kang Guo
  • Dayun Feng
  • Yan Qu
  • Cell Prolif..2020 Feb;53(2):e12759. doi: 10.1111/cpr.12759.Epub 2020-01-10.

プレグナンX受容体-シトクロムP450s軸の活性化：PEG化リポソームの強化された血液クリアランス促進現象の可能な理由

Activation of Pregnane X Receptor-Cytochrome P450s Axis: A Possible Reason for the Enhanced Accelerated Blood Clearance Phenomenon of PEGylated Liposomes In Vivo.
  • Fengling Wang
  • Huihui Wang
  • Yifan Wu
  • Lei Wang
  • Ling Zhang
  • Xi Ye
  • Daiyin Peng
  • Weidong Chen
  • Drug Metab. Dispos..2019 08;47(8):785-793. dmd.119.086769. doi: 10.1124/dmd.119.086769.Epub 2019-05-22.

切除不能な肝細胞がんに対する肝動脈化学塞栓療法とスニチニブ。PRODIGE 16試験の結果

Liver transarterial chemoembolization and sunitinib for unresectable hepatocellular carcinoma: Results of the PRODIGE 16 study.
  • Anthony Turpin
  • Thierry de Baere
  • Alexandra Heurgué
  • Karine Le Malicot
  • Isabelle Ollivier-Hourmand
  • Thierry Lecomte
  • Hervé Perrier
  • Julien Vergniol
  • David Sefrioui
  • Yves Rinaldi
  • Julien Edeline
  • Jean-Louis Jouve
  • Christine Silvain
  • Yves Becouarn
  • Barbara Dauvois
  • Mathieu Baconnier
  • Maryline Debette-Gratien
  • Gael Deplanque
  • Sébastien Dharancy
  • Côme Lepage
  • Mohamed Hebbar
  • Clin Res Hepatol Gastroenterol.2020 Jun;S2210-7401(20)30157-1. doi: 10.1016/j.clinre.2020.05.012.Epub 2020-06-21.

アルゼンチンにおける事故、自殺、殺人による死亡率の傾向の再計算（1997-2018年）事故、自殺、殺人による死亡率の傾向の再計算（1997-2018年）アルゼンチンにおける事故、自殺、殺人による死亡率の傾向の再計算

[Recalculation of trends in mortality from accidents, suicides, and homicides in Argentina, 1997-2018Recálculo das tendências de mortalidade por acidentes, suicídios e homicídios na Argentina, 1997-2018].
  • Adrián Santoro
  • Rev. Panam. Salud Publica.2020;44:e74. RPSP.2020.74. doi: 10.26633/RPSP.2020.74.Epub 2020-07-15.

浸透性角膜形成術におけるエキシマレーザーとフェムト秒レーザーアシストトレフィネーションの比較。レトロスペクティブ研究

Comparison of Excimer Laser Versus Femtosecond Laser Assisted Trephination in Penetrating Keratoplasty: A Retrospective Study.
  • Gábor Tóth
  • Nóra Szentmáry
  • Achim Langenbucher
  • Elina Akhmedova
  • Moatasem El-Husseiny
  • Berthold Seitz
  • Adv Ther.2019 12;36(12):3471-3482. 10.1007/s12325-019-01120-3. doi: 10.1007/s12325-019-01120-3.Epub 2019-10-24.

ベースラインのKarnofskyパフォーマンスステータスは、転移性疾患に対する頭蓋内放射線治療終了後30日以内の死亡を独立して予測する

Baseline Karnofsky performance status is independently predictive of death within 30 days of intracranial radiation therapy completion for metastatic disease.
  • Shearwood McClelland Iii
  • Namita Agrawal
  • May F Elbanna
  • Kevin Shiue
  • Gregory K Bartlett
  • Tim Lautenschlaeger
  • Richard C Zellars
  • Gordon A Watson
  • Susannah G Ellsworth
  • Rep Pract Oncol Radiother.2020 Jul-Aug;25(4):698-700. S1507-1367(20)30028-6. doi: 10.1016/j.rpor.2020.02.014.Epub 2020-02-24.

薬剤溶出ステントまたは薬剤溶出バルーン治療後の薬剤溶出型とベアメタル型のステント内再狭窄の臨床成績。システマティックレビューとメタアナリシス

Clinical Outcomes of Drug-Eluting versus Bare-Metal In-Stent Restenosis after the Treatment of Drug-Eluting Stent or Drug-Eluting Balloon: A Systematic Review and Meta-Analysis.
  • Yi-Xing Yang
  • Yin Liu
  • Chang-Ping Li
  • Peng-Ju Lu
  • Jiao Wang
  • Jing Gao
  • J Interv Cardiol.2020;2020:8179849. doi: 10.1155/2020/8179849.Epub 2020-06-26.

大細胞肺神経内分泌がんにおけるPD-L1発現パターン：これらの患者における免疫療法の使用の潜在的な意味合い：GFPC 03-2017「EPNEC」試験

PD-L1-expression patterns in large-cell neuroendocrine carcinoma of the lung: potential implications for use of immunotherapy in these patients: the GFPC 03-2017 "EPNEC" study.
  • Dominique Arpin
  • Marie-Christine Charpentier
  • Marie Bernardi
  • Isabelle Monnet
  • Aurelie Boni
  • Emmanuel Watkin
  • Isabelle Goubin-Versini
  • Régine Lamy
  • Laurence Gérinière
  • Margaux Geier
  • Fabien Forest
  • Radj Gervais
  • Anne Madrosyk
  • Florian Guisier
  • Cécile Serrand
  • Chrystèle Locher
  • Chantal Decroisette
  • Pierre Fournel
  • Jean-Bernard Auliac
  • Thierry Jeanfaivre
  • Jacques Letreut
  • Hélène Doubre
  • Geraldine Francois
  • Nicolas Piton
  • Christos Chouaïd
  • Diane Damotte
  • Ther Adv Med Oncol.2020;12:1758835920937972. 10.1177_1758835920937972. doi: 10.1177/1758835920937972.Epub 2020-07-07.

胃切除術を受けた高齢の胃がん患者における非在宅退院の予測には、修正されたFrailty Indexが有用である

Modified Frailty Index is Useful in Predicting Non-home Discharge in Elderly Patients with Gastric Cancer Who Undergo Gastrectomy.
  • Tomohiro Osaki
  • Hiroaki Saito
  • Shota Shimizu
  • Yuki Murakami
  • Kozo Miyatani
  • Tomoyuki Matsunaga
  • Shigeru Tatebe
  • Masahide Ikeguchi
  • Yoshiyuki Fujiwara
  • World J Surg.2020 Jul;10.1007/s00268-020-05691-z. doi: 10.1007/s00268-020-05691-z.Epub 2020-07-13.

前進浸透膜の防汚性を向上させるために、銀をコアにした金属有機フレームワーク（Ag-MOF）の機能化を行い、銀をコアにした金属有機フレームワーク（Ag-MOF）をその場で成長させることを試みた

In-Situ Ag-MOFs Growth on Pre-Grafted Zwitterions Imparts Outstanding Antifouling Properties to Forward Osmosis Membranes.
  • Mehdi Pejman
  • Mostafa Dadashi Firouzjaei
  • Sadegh Aghapour Aktij
  • Parnab Das
  • Ehsan Zolghadr
  • Hesam Jafarian
  • Ahmad Arabi Shamsabadi
  • Mark A Elliott
  • Mohtada Sadrzadeh
  • Marco Sangermano
  • Ahmad Rahimpour
  • Alberto Tiraferri
  • ACS Appl Mater Interfaces.2020 Jul;doi: 10.1021/acsami.0c12141.Epub 2020-07-17.

630人の患者を対象とした好酸球性食道炎に対するプロトンポンプ阻害薬治療の有効性：EoE connect registryの結果

Efficacy of proton pump inhibitor therapy for eosinophilic oesophagitis in 630 patients: results from the EoE connect registry.
  • Emilio J Laserna-Mendieta
  • Sergio Casabona
  • Danila Guagnozzi
  • Edoardo Savarino
  • Antonia Perelló
  • Antonio Guardiola-Arévalo
  • Jesús Barrio
  • Isabel Pérez-Martínez
  • Anne Lund Krarup
  • Javier Alcedo
  • Susana de la Riva
  • Esther Rey-Iborra
  • Cecilio Santander
  • Ángel Arias
  • Alfredo J Lucendo
  • Aliment. Pharmacol. Ther..2020 Jul;doi: 10.1111/apt.15957.Epub 2020-07-17.

マクロテクスチャーの乳房インプラントおよび乳房の未分化大細胞リンパ腫を有する女性におけるBRCA1/2変異の有病率の増加

Increased prevalence of BRCA1/2 mutations in women with macro-textured breast implants and anaplastic large cell lymphoma of the breast.
  • Mintsje De Boer
  • Michael Hauptmann
  • Nathalie J Hijmering
  • Carel J M van Noesel
  • Hinne A Rakhorst
  • Hanne Ej Meijers-Heijboer
  • Jan Paul De Boer
  • René Rwj van der Hulst
  • Daphne De Jong
  • Flora E van Leeuwen
  • Blood.2020 May;blood.2019004498. doi: 10.1182/blood.2019004498.Epub 2020-05-26.

C9orf72は腸内細菌によって誘導される全身および神経の炎症を抑制します

C9orf72 suppresses systemic and neural inflammation induced by gut bacteria.
  • Aaron Burberry
  • Michael F Wells
  • Francesco Limone
  • Alexander Couto
  • Kevin S Smith
  • James Keaney
  • Gaëlle Gillet
  • Nick van Gastel
  • Jin-Yuan Wang
  • Olli Pietilainen
  • Menglu Qian
  • Pierce Eggan
  • Christopher Cantrell
  • Joanie Mok
  • Irena Kadiu
  • David T Scadden
  • Kevin Eggan
  • Nature.2020 06;582(7810):89-94. 10.1038/s41586-020-2288-7. doi: 10.1038/s41586-020-2288-7.Epub 2020-05-13.

レシピエント精巣における生殖細胞枯渇は、レチノイン酸不足を介して、整形外科的に移植された精巣片の造精子形成に悪影響を及ぼす

Germ cell depletion in recipient testis has adverse effects on spermatogenesis in orthotopically transplanted testis pieces via retinoic acid insufficiency.
  • Akihiro Tsuchimoto
  • Masaaki Tone
  • Narumi Ogonuki
  • Masashi Hada
  • Atsuo Ogura
  • Seiji Takashima
  • Sci Rep.2020 Jul;10(1):10796. 10.1038/s41598-020-67595-1. doi: 10.1038/s41598-020-67595-1.Epub 2020-07-01.

ForenSeq™ DNA Signature Prep Kitとレーザーで微小解剖した細胞との互換性。細胞数の少ないサンプルで発生する問題点を探る

Compatibility of the ForenSeq™ DNA Signature Prep Kit with laser microdissected cells: An exploration of issues that arise with samples containing low cell numbers.
  • Ryan England
  • Gemma Nancollis
  • Janet Stacey
  • Andrew Sarman
  • Jason Min
  • SallyAnn Harbison
  • Forensic Sci Int Genet.2020 Jul;47:102278. S1872-4973(20)30051-X. doi: 10.1016/j.fsigen.2020.102278.Epub 2020-05-01.

上腕骨近位部骨折に対するステムドヘミア関節形成術と比較した逆全肩関節形成術：5946人の患者のレジストリ分析

Reverse total shoulder arthroplasty compared to stemmed hemiarthroplasty for proximal humeral fractures: a registry analysis of 5946 patients.
  • Owain Critchley
  • Andrew McLean
  • Richard Page
  • Fraser Taylor
  • Stephen Graves
  • Michelle Lorimer
  • Yi Peng
  • Alesha Hatton
  • Gregory Bain
  • J Shoulder Elbow Surg.2020 Jun;S1058-2746(20)30306-2. doi: 10.1016/j.jse.2020.04.005.Epub 2020-06-09.

母性ベタインサプリメントは、SREBP2とCYP7A1遺伝子のエピジェネティックな変調を持つ鶏の子孫における肝コレステロール沈着を減少させます

Maternal betaine supplementation decreases hepatic cholesterol deposition in chicken offspring with epigenetic modulation of SREBP2 and CYP7A1 genes.
  • Yun Hu
  • Yue Feng
  • Zequn Ding
  • Lilei Lv
  • Yi Sui
  • Qinwei Sun
  • Halima Abobaker
  • Demin Cai
  • Ruqian Zhao
  • Poult. Sci..2020 Jun;99(6):3111-3120. S0032-5791(20)30076-6. doi: 10.1016/j.psj.2019.12.058.Epub 2020-04-14.

16項目の変形性膝関節症患者教育質問票（KOPEQ）に基づいた7項目の膝関節置換術患者教育質問票（KR-PEQ-7）の検証

Validation of the 7-item knee replacement patient education questionnaire (KR-PEQ-7), based on the 16-item knee osteoarthritis patient education questionnaire (KOPEQ).
  • Erika O Huber
  • Axel Boger
  • André Meichtry
  • Caroline H Bastiaenen
  • BMC Musculoskelet Disord.2020 Jul;21(1):468. 10.1186/s12891-020-03476-y. doi: 10.1186/s12891-020-03476-y.Epub 2020-07-16.

凍結精子症の男性からの射精精精子を3個以下にするための改良透過性凍結精子無添加ガラス固化法と、この方法で生まれた14人の子供の7年間の追跡調査

Modified permeable cryoprotectant-free vitrification method for three or fewer ejaculated spermatozoa from cryptozoospermic men and 7-year follow-up study of 14 children born from this method.
  • Motoharu Ohno
  • Atsushi Tanaka
  • Motoi Nagayoshi
  • Takashi Yamaguchi
  • Youichi Takemoto
  • Izumi Tanaka
  • Seiji Watanabe
  • Atsuo Itakura
  • Hum. Reprod..2020 May;35(5):1019-1028. 5834445. doi: 10.1093/humrep/deaa072.

Affective Switch Associated Associated With Oral, Low Dose Ketamine Treatment in a Patient With Treatment Resistant Bipolar I Depression.症例報告と文献レビュー

Affective Switch Associated With Oral, Low Dose Ketamine Treatment in a Patient With Treatment Resistant Bipolar I Depression. Case Report and Literature Review.
  • Alina Wilkowska
  • Łukasz Szałach
  • Jakub Słupski
  • Aleksandra Wielewicka
  • Małgorzata Czarnota
  • Maria Gałuszko-Węgielnik
  • Mariusz S Wiglusz
  • Wiesław J Cubała
  • Front Psychiatry.2020;11:516. doi: 10.3389/fpsyt.2020.00516.Epub 2020-06-03.

入院患者における介護者による疼痛管理介入が患者、介護者、提供者、医療システムの転帰に及ぼす影響。システマティックレビュー

The effect of caregiver-facilitated pain management interventions in hospitalized patients on patient, caregiver, provider and health system outcomes: A systematic review.
  • Israt Yasmeen
  • Karla D Krewulak
  • Cherri Zhang
  • Henry T Stelfox
  • Kirsten M Fiest
  • J Pain Symptom Manage.2020 Jun;S0885-3924(20)30574-1. doi: 10.1016/j.jpainsymman.2020.06.030.Epub 2020-06-29.

石油系炭化水素に対するプランクトン群集の反応をカスタマイズした場合のエンドポイントとしての周期密度。毒性効果のレベルは、適切な時間スケールと一致させる必要がある

Periodic density as an endpoint of customized plankton community responses to petroleum hydrocarbons: A level of toxic effect should be matched with a suitable time scale.
  • Changyou Wang
  • Siwen Wang
  • Xinming Jiao
  • Bin Yang
  • Shengkang Liang
  • Zhuhua Luo
  • Longjiang Mao
  • Ecotoxicol. Environ. Saf..2020 Sep;201:110723. S0147-6513(20)30562-5. doi: 10.1016/j.ecoenv.2020.110723.Epub 2020-05-30.

外傷性脳損傷患者における選択的脳冷却用鼻咽頭カテーテルの有効性と安全性。プロスペクティブ、非ランダム化パイロット研究

Efficacy and Safety of a Nasopharyngeal Catheter for Selective Brain Cooling in Patients with Traumatic Brain Injury: A Prospective, Non-randomized Pilot Study.
  • Raphael Einsfeld Simões Ferreira
  • Bernardo Lembo Conde de Paiva
  • Flávio Geraldo Rezende de Freitas
  • Flávia Ribeiro Machado
  • Gisele Sampaio Silva
  • Rafael Mônaco Raposo
  • Conrado Feisthauer Silveira
  • Ricardo Silva Centeno
  • Neurocrit Care.2020 Jul;10.1007/s12028-020-01052-9. doi: 10.1007/s12028-020-01052-9.Epub 2020-07-17.

"実生活"多環芳香族炭化水素（PAH）混合物は、hCG、hPLおよびhPLGFレベルを調節し、ヒト胎盤細胞株におけるMMP-2/MMP-9比およびVEGF発現の生理的比率を混乱させる

"Real life" polycyclic aromatic hydrocarbon (PAH) mixtures modulate hCG, hPL and hPLGF levels and disrupt the physiological ratio of MMP-2 to MMP-9 and VEGF expression in human placenta cell lines.
  • Eliza Drwal
  • Agnieszka Rak
  • Wacław Tworzydło
  • Ewa Łucja Gregoraszczuk
  • Reprod. Toxicol..2020 Aug;95:1-10. S0890-6238(20)30019-8. doi: 10.1016/j.reprotox.2020.02.006.Epub 2020-05-11.

潜在クラス解析により同定された非ステロイド性抗炎症性疾患増悪性呼吸器疾患のサブフェノタイプ

Subphenotypes of nonsteroidal antiinflammatory disease-exacerbated respiratory disease identified by latent class analysis.
  • Natalia Celejewska-Wójcik
  • Krzysztof Wójcik
  • Maria Ignacak-Popiel
  • Adam Ćmiel
  • Katarzyna Tyrak
  • Anna Gielicz
  • Aleksander Kania
  • Paweł Nastałek
  • Marek Sanak
  • Lucyna Mastalerz
  • Allergy.2020 04;75(4):831-840. doi: 10.1111/all.14141.Epub 2020-01-28.

ヘキサクロロナフタレンは、活性酸素の産生促進機構を介してミトコンドリア依存性の神経毒性を誘導する

Hexachloronaphthalene Induces Mitochondrial-Dependent Neurotoxicity via a Mechanism of Enhanced Production of Reactive Oxygen Species.
  • Malwina Lisek
  • Joanna Stragierowicz
  • Feng Guo
  • Philipp P Prosseda
  • Magdalena Wiktorska
  • Bozena Ferenc
  • Anna Kilanowicz
  • Ludmila Zylinska
  • Tomasz Boczek
  • Oxid Med Cell Longev.2020;2020:2479234. doi: 10.1155/2020/2479234.Epub 2020-06-26.

IVA-B期の口腔咽頭癌または咽頭下癌患者を対象とした臓器温存療法としての体積変調アーク療法を用いた導入化学療法と化学放射線療法の長期治療成績の検討

Long-term outcomes of induction chemotherapy followed by chemoradiotherapy using volumetric-modulated arc therapy as an organ preservation approach in patients with stage IVA-B oropharyngeal or hypopharyngeal cancers.
  • Katsumaro Kubo
  • Yuji Murakami
  • Masahiro Kenjo
  • Nobuki Imano
  • Yuki Takeuchi
  • Ikuno Nishibuchi
  • Tomoki Kimura
  • Daisuke Kawahara
  • Tsutomu Ueda
  • Sachio Takeno
  • Yasushi Nagata
  • J. Radiat. Res..2020 Jul;61(4):554-562. 5858247. doi: 10.1093/jrr/rraa033.

ハンガリーの一般成人集団におけるeHealthリテラシーと患者報告による外来診療の経験の探索。横断的研究

Exploring eHealth Literacy and Patient-Reported Experiences with Outpatient Care in the Hungarian General Adult Population: A Cross-Sectional Study.
  • Zsombor Zrubka
  • Óscar Brito Fernandes
  • Petra Baji
  • Ottó Hajdu
  • Levente Kovács
  • Dionne Kringos
  • Niek Klazinga
  • László Gulácsi
  • Valentin Brodszky
  • Fanni Rencz
  • Márta Péntek
  • J. Med. Internet Res..2020 Jun;doi: 10.2196/19013.Epub 2020-06-15.

健康な白人患者における重度の外傷が引き金となった細菌性血管腫症．症例報告

Bacillary angiomatosis triggered by severe trauma in a healthy Caucasian patient: A case report.
  • Mihaela Balaban
  • Roxana Ioana Nedelcu
  • Gabriela Balmes
  • Teodora Adela Todorovic
  • Alice Brinzea
  • Luciana Nichita
  • Cristiana Gabriela Popp
  • Razvan Theodor Andrei
  • Sabina Andrada Zurac
  • Daniela Adriana Ion
  • Gabriela Turcu
  • Exp Ther Med.2020 Jul;20(1):56-60. ETM-0-0-8260. doi: 10.3892/etm.2019.8260.Epub 2019-11-29.

リボソームリサイクル反応のためのモデルポストターミネーション複合体(PoTC)の化学的・構造的特性評価RRFとEF-GによるmRNAの放出の証拠

Chemical and structural characterization of a model Post-Termination Complex (PoTC) for the ribosome recycling reaction: Evidence for the release of the mRNA by RRF and EF-G.
  • Nobuhiro Iwakura
  • Takeshi Yokoyama
  • Fabio Quaglia
  • Kaoru Mitsuoka
  • Kazuhiro Mio
  • Hideki Shigematsu
  • Mikako Shirouzu
  • Akira Kaji
  • Hideko Kaji
  • PLoS ONE.2017;12(5):e0177972. PONE-D-16-39755. doi: 10.1371/journal.pone.0177972.Epub 2017-05-24.

クエン酸第二鉄調節因子FecRは、ユニークなツインアルギニン輸送依存性メカニズムを介して細菌内膜を横断してトランスロケーションされている

Ferric Citrate Regulator FecR Is Translocated across the Bacterial Inner Membrane via a Unique Twin-Arginine Transport-Dependent Mechanism.
  • Ian J Passmore
  • Jennifer M Dow
  • Francesc Coll
  • Jon Cuccui
  • Tracy Palmer
  • Brendan W Wren
  • J. Bacteriol..2020 Apr;202(9). e00541-19. doi: 10.1128/JB.00541-19.Epub 2020-04-09.

柔軟性の高い高分解能質量分析アプローチによる都市排水中の新規精神活性物質のスクリーニング

Flexible high resolution-mass spectrometry approach for screening new psychoactive substances in urban wastewater.
  • Noelia Salgueiro-González
  • Sara Castiglioni
  • Emma Gracia-Lor
  • Lubertus Bijlsma
  • Alberto Celma
  • Renzo Bagnati
  • Félix Hernández
  • Ettore Zuccato
  • Sci. Total Environ..2019 Nov;689:679-690. S0048-9697(19)32909-2. doi: 10.1016/j.scitotenv.2019.06.336.Epub 2019-06-26.

エトリパミル点鼻スプレーによる上室性頻拍から副鼻腔リズムへの迅速変換

Etripamil Nasal Spray for Rapid Conversion of Supraventricular Tachycardia to Sinus Rhythm.
  • Bruce S Stambler
  • Paul Dorian
  • Philip T Sager
  • Douglas Wight
  • Philippe Douville
  • Diane Potvin
  • Pirouz Shamszad
  • Ronald J Haberman
  • Richard S Kuk
  • Dhanunjaya R Lakkireddy
  • Jose M Teixeira
  • Kenneth C Bilchick
  • Roger S Damle
  • Robert C Bernstein
  • Wilson W Lam
  • Gearoid O'Neill
  • Peter A Noseworthy
  • Kalpathi L Venkatachalam
  • Benoit Coutu
  • Blandine Mondésert
  • Francis Plat
  • J. Am. Coll. Cardiol..2018 07;72(5):489-497. S0735-1097(18)34992-1. doi: 10.1016/j.jacc.2018.04.082.

ガーナにおけるサルシパルム原虫ヒスチジンリッチプロテイン2の多様性

Plasmodium falciparum histidine-rich protein 2 diversity in Ghana.
  • Otchere Addai-Mensah
  • Bismarck Dinko
  • Mark Noagbe
  • Selassie Louis Ameke
  • Max Efui Annani-Akollor
  • Eddie-Williams Owiredu
  • Kofi Mensah
  • Richmond Tackie
  • Eliezer Togbe
  • Comfort Agyare-Kwabi
  • Charles Gyasi
  • Constance Adu-Gyamfi
  • Alexander Yaw Debrah
  • Malar. J..2020 Jul;19(1):256. 10.1186/s12936-020-03328-z. doi: 10.1186/s12936-020-03328-z.Epub 2020-07-16.

LC-MSおよびHS-SPME-GC-O-MSによるニュージーランド産4品種のフェジョア果汁中のフェノール化合物およびアロマ活性化合物の特性評価

Characterization of phenolic compounds and aroma active compounds in feijoa juice from four New Zealand grown cultivars by LC-MS and HS-SPME-GC-O-MS.
  • Yaoyao Peng
  • Karen Suzanne Bishop
  • Jingying Zhang
  • Donglin Chen
  • Siew Young Quek
  • Food Res. Int..2020 Mar;129:108873. S0963-9969(19)30759-8. doi: 10.1016/j.foodres.2019.108873.Epub 2019-12-05.

健康な小児1300人における三尖頭環状面収縮期エクスカーションと僧帽弁環状面収縮期エクスカーションの心臓基準値。単施設での結果

Tricuspid annular plane systolic excursion and mitral annular plane systolic excursion cardiac reference values in 1300 healthy children: Single-center results.
  • Mahmut Keskin
  • Özkan Kaya
  • Tamer Yoldaş
  • Selmin Karademir
  • Utku Arman Örün
  • Senem Özgür
  • Vehbi Doğan
  • Osman Gürdal
  • Echocardiography.2020 Jul;doi: 10.1111/echo.14793.Epub 2020-07-20.

COVID-19患者の治療における回復期血漿と間葉系幹細胞の相乗的役割：不顕性症例報告

A synergistic role of convalescent plasma and mesenchymal stem cells in the treatment of severely ill COVID-19 patients: a clinical case report.
  • Hongbing Peng
  • Tiefeng Gong
  • Xiaoying Huang
  • Xun Sun
  • Hong Luo
  • Weizhong Wang
  • Junbiao Luo
  • Baowei Luo
  • Yanhui Chen
  • Xingxing Wang
  • Haifeng Long
  • Hua Mei
  • Chuang Li
  • Yanni Dai
  • Honghui Li
  • Stem Cell Res Ther.2020 Jul;11(1):291. 10.1186/s13287-020-01802-8. doi: 10.1186/s13287-020-01802-8.Epub 2020-07-16.

CNS受容体への結合を低減した抗結核性ポリハロゲン化フェノチアジンおよびフェノセレナジン

Antitubercular polyhalogenated phenothiazines and phenoselenazine with reduced binding to CNS receptors.
  • Maria Giulia Nizi
  • Jenny Desantis
  • Yoshio Nakatani
  • Serena Massari
  • Maria Angela Mazzarella
  • Gauri Shetye
  • Stefano Sabatini
  • Maria Letizia Barreca
  • Giuseppe Manfroni
  • Tommaso Felicetti
  • Rowena Rushton-Green
  • Kiel Hards
  • Gniewomir Latacz
  • Grzegorz Satała
  • Andrzej J Bojarski
  • Violetta Cecchetti
  • Michal H Kolář
  • Jadwiga Handzlik
  • Gregory M Cook
  • Scott G Franzblau
  • Oriana Tabarrini
  • Eur J Med Chem.2020 Jun;201:112420. S0223-5234(20)30391-3. doi: 10.1016/j.ejmech.2020.112420.Epub 2020-06-05.

思春期における甘味料摂取の神経代謝効果とラットの抑うつ様表現型との関連

Neurometabolic effects of sweetened solution intake during adolescence related to depressive-like phenotype in rats.
  • Danusa Mar Arcego
  • Laura Bem Olivo
  • Rafael Oliveira Moraes
  • Emily Dos Santos Garcia
  • Ana Caroline Silveira
  • Rachel Krolow
  • Natividade de Sá Couto-Pereira
  • Carine Lampert
  • Ana Paula Toniazzo
  • Fabrício do Couto Nicola
  • Eduardo Farias Sanches
  • Dirceu Aristimunha
  • Juliana Bender Hoppe
  • Caroline Peres Klein
  • Fernanda Urruth Fontella
  • Roberto Farina Almeida
  • Giovana Duzzo Gamaro
  • Fernanda Carolina Telles da Silva Fróes
  • Marina Concli Leite
  • Carlos Alexandre Netto
  • Denise Maria Zancan
  • Carla Dalmaz
  • Nutrition.2020 Jul - Aug;75-76:110770. S0899-9007(20)30053-8. doi: 10.1016/j.nut.2020.110770.Epub 2020-02-22.

骨粗鬆症性椎体圧迫骨折に対する椎骨形成術と骨形成術の費用と術後成績の比較。州レベルの外来患者データベースからの分析

Comparison of Costs and Postoperative Outcomes between Vertebroplasty and Kyphoplasty for Osteoporotic Vertebral Compression Fractures: Analysis from a State-Level Outpatient Database.
  • Mohammed Ali Alvi
  • Jad Zreik
  • Yagiz U Yolcu
  • Anshit Goyal
  • Dong Kun Kim
  • David F Kallmes
  • Brett A Freedman
  • Mohamad Bydon
  • World Neurosurg.2020 Jun;S1878-8750(20)31264-X. doi: 10.1016/j.wneu.2020.06.008.Epub 2020-06-10.

エッセンシャルオイルナノエマルジョン（CLEO-NE）は、抗血管新生活性を有するヒトA549肺がん細胞における安全な細胞依存性アポトーシス誘導剤です

essential oil nanoemulsion (CLEO-NE), a safe cell-depended apoptosis inducer in human A549 lung cancer cells with anti-angiogenic activity.
  • Elnaz Yousefian Rad
  • Masoud Homayouni Tabrizi
  • Pouran Ardalan
  • Seyed Mohammad Reza Seyedi
  • Samira Yadamani
  • Parisa Zamani-Esmati
  • Nastaran Haghani Sereshkeh
  • J Microencapsul.2020 Aug;37(5):394-402. doi: 10.1080/02652048.2020.1767223.Epub 2020-05-19.

短腸症候群と牛乳アレルギーを合併した小児におけるコハク酸メチルプレドニゾロンナトリウムによるアナフィラキシーショック

Anaphylactic shock with methylprednisolone sodium succinate in a child with short bowel syndrome and cow's milk allergy.
  • Federica Porcaro
  • Maria Giovanna Paglietti
  • Antonella Diamanti
  • Francesca Petreschi
  • Alessandra Schiavino
  • Valentina Negro
  • Valentina Pecora
  • Alessandro Fiocchi
  • Renato Cutrera
  • Ital J Pediatr.2017 Nov;43(1):104. 10.1186/s13052-017-0422-4. doi: 10.1186/s13052-017-0422-4.Epub 2017-11-17.

遺伝毒性リスク評価のための新しいツール。テロメアおよびセントロメア染色後の半自動スコアリングを用いたサイトカインブロック小核試験の再評価

A new tool for genotoxic risk assessment: Reevaluation of the cytokinesis-block micronucleus assay using semi-automated scoring following telomere and centromere staining.
  • Narjes Zaguia
  • Eric Laplagne
  • Bruno Colicchio
  • Olivier Cariou
  • Mustafa Al Jawhari
  • Leonhard Heidingsfelder
  • William M Hempel
  • Besma Bel Hadj Jrad
  • Eric Jeandidier
  • Alain Dieterlen
  • Patrice Carde
  • Philippe Voisin
  • Radhia M'kacher
  • Mutat. Res..2020 Feb - Mar;850-851:503143. S1383-5718(20)30013-9. doi: 10.1016/j.mrgentox.2020.503143.Epub 2020-01-22.

局所進行性胃食道腺癌患者における生存率の予後因子としてのサルコペニア

Sarcopenia as a prognostic factor for survival in patients with locally advanced gastroesophageal adenocarcinoma.
  • Christine Koch
  • Cornelius Reitz
  • Teresa Schreckenbach
  • Katrin Eichler
  • Natalie Filmann
  • Salah-Eddin Al-Batran
  • Thorsten Götze
  • Stefan Zeuzem
  • Wolf Otto Bechstein
  • Thomas Kraus
  • Jörg Bojunga
  • Markus Düx
  • Jörg Trojan
  • Irina Blumenstein
  • PLoS ONE.2019;14(10):e0223613. PONE-D-19-16120. doi: 10.1371/journal.pone.0223613.Epub 2019-10-22.

ガイドラインに基づいた薬剤溶出ステントの使用の費用対効果：7年間の多施設での経験の傾向スコアマッチド解析

The cost-effectiveness of guideline-driven use of drug-eluting stents: propensity-score matched analysis of a seven-year multicentre experience.
  • Thathya V Ariyaratne
  • Zanfina Ademi
  • Richard Ofori-Asenso
  • Molla M Huq
  • Stephen J Duffy
  • Bryan P Yan
  • Andrew E Ajani
  • David J Clark
  • Baki Billah
  • Angela L Brennan
  • Gishel New
  • Nick Andrianopoulos
  • Christopher M Reid
  • Curr Med Res Opin.2020 Mar;36(3):419-426. doi: 10.1080/03007995.2019.1708288.Epub 2020-01-19.

大腸菌の10-ヒドロキシゲラニオールオキシドレダクターゼとイリドイド合成酵素の特性評価と、NADP-NADPH補因子のリサイクルを特徴とする大腸菌におけるネペラクトールの生物学的調製への応用

Characterization of Camptotheca acuminata 10-Hydroxygeraniol oxidoreductase and iridoid synthase and their application in biological preparation of nepetalactol in Escherichia coli featuring NADP - NADPH cofactors recycling.
  • Annoor Awadasseid
  • Wei Li
  • Zhan Liu
  • Chong Qiao
  • Jing Pang
  • Guolin Zhang
  • Yinggang Luo
  • Int. J. Biol. Macromol..2020 Jun;S0141-8130(20)33677-1. doi: 10.1016/j.ijbiomac.2020.06.223.Epub 2020-06-26.

プロスタグランジン輸送体OATP2A1/SLCO2A1の胎盤-母体間ホルモンシグナル伝達と陣痛誘発への寄与

Contribution of Prostaglandin Transporter OATP2A1/SLCO2A1 to Placenta-to-Maternal Hormone Signaling and Labor Induction.
  • Mai Inagaki
  • Tomohiro Nishimura
  • Takeo Nakanishi
  • Hiroaki Shimada
  • Saki Noguchi
  • Shin-Ichi Akanuma
  • Masanori Tachikawa
  • Ken-Ichi Hosoya
  • Ikumi Tamai
  • Emi Nakashima
  • Masatoshi Tomi
  • iScience.2020 May;23(5):101098. S2589-0042(20)30283-2. doi: 10.1016/j.isci.2020.101098.Epub 2020-04-27.

腰椎変性疾患によるドロップフットに対する早期減圧手術と遅延減圧手術後の神経機能について

Neurological function following early versus delayed decompression surgery for drop foot caused by lumbar degenerative diseases.
  • Hiroaki Nakashima
  • Yoshimoto Ishikawa
  • Tokumi Kanemura
  • Fumihiko Kato
  • Kotaro Satake
  • Keigo Ito
  • Kenyu Ito
  • Kei Ando
  • Kazuyoshi Kobayashi
  • Naoki Ishiguro
  • Shiro Imagama
  • J Clin Neurosci.2020 Feb;72:39-42. S0967-5868(19)31926-5. doi: 10.1016/j.jocn.2020.01.039.Epub 2020-01-23.

アフリカ南部の考古学的な有機物の容器と材料のデータベース、紀元前800年から紀元1500年：採食から家畜飼育への移行のために考えられる意味合い

A southern African archaeological database of organic containers and materials, 800 cal BC to cal AD 1500: Possible implications for the transition from foraging to livestock-keeping.
  • Faye Lander
  • Thembi Russell
  • PLoS ONE.2020;15(7):e0235226. PONE-D-20-07767. doi: 10.1371/journal.pone.0235226.Epub 2020-07-08.

ウォーターパイプ/ホッカースモークへの短期暴露は、多動性血小板活性化状態を誘発し、血栓形成のリスクを増加させる

Short-Term Exposure to Waterpipe/Hookah Smoke Triggers a Hyperactive Platelet Activation State and Increases the Risk of Thrombogenesis.
  • Ahmed B Alarabi
  • Zubair A Karim
  • Jean E Montes Ramirez
  • Keziah R Hernandez
  • Patricia A Lozano
  • José O Rivera
  • Fatima Z Alshbool
  • Fadi T Khasawneh
  • Arterioscler. Thromb. Vasc. Biol..2020 02;40(2):335-349. doi: 10.1161/ATVBAHA.119.313435.Epub 2020-01-16.

横紋筋肉腫におけるFGFR4チロシンキナーゼ変異に起因するポナチニブ抵抗性メカニズムの分子モデリング戦略による解明

Insight into ponatinib resistance mechanisms in rhabdomyosarcoma caused by the mutations in FGFR4 tyrosine kinase using molecular modeling strategies.
  • Chao Wu
  • Xiaolu Chen
  • Daoxing Chen
  • Qinqin Xia
  • Zhiguo Liu
  • Fuchuan Li
  • Yuxiang Yan
  • Yuepiao Cai
  • Int. J. Biol. Macromol..2019 Aug;135:294-302. S0141-8130(19)30432-5. doi: 10.1016/j.ijbiomac.2019.05.138.Epub 2019-05-22.

カルシウムフリーおよびサイトカラシンB処理は、逐次エレクトロポレーションによるフロックスマウス作製のための2細胞期胚におけるブラストメア融合を阻害する

Calcium-Free and Cytochalasin B Treatment Inhibits Blastomere Fusion in 2-Cell Stage Embryos for the Generation of Floxed Mice via Sequential Electroporation.
  • Takuro Horii
  • Ryosuke Kobayashi
  • Mika Kimura
  • Sumiyo Morita
  • Izuho Hatada
  • Cells.2020 Apr;9(5). E1088. doi: 10.3390/cells9051088.Epub 2020-04-28.

研究「病気の防衛複合体から回復する」ヘルパーT細胞の免疫メカニズムを「フクシー」理論に基づいてクリアリング熱悪を徹底的に栄養腎臓治療再発血熱症候群乾癬

Research "recover from illness defense complex" helper T cell immune mechanisms based on the "Fuxie" theory clearing away heat evil thoroughly nourishing kidney treatment of recurrent blood-heat syndrome Psoriasis.
  • Mao Li
  • Xia Hu
  • Ping-Sheng Hao
  • Medicine (Baltimore).2020 May;99(20):e20161. 00005792-202005150-00048. doi: 10.1097/MD.0000000000020161.

気管支肺胞液（BALF）および呼気凝縮液（EBC）中の呼吸代謝物は、重度の馬喘息を患っている馬と健康な馬を区別することができる

Respiratory metabolites in bronchoalveolar lavage fluid (BALF) and exhaled breath condensate (EBC) can differentiate horses affected by severe equine asthma from healthy horses.
  • Marilena Bazzano
  • Luca Laghi
  • Chenglin Zhu
  • Gian Enrico Magi
  • Beniamino Tesei
  • Fulvio Laus
  • BMC Vet. Res..2020 Jul;16(1):233. 10.1186/s12917-020-02446-9. doi: 10.1186/s12917-020-02446-9.Epub 2020-07-08.

トランスポゾンを用いた解析により、トリプルネガティブ乳がんに関与していることが明らかになった

A Transposon-based Analysis Reveals Is Involved in Triple-Negative Breast Cancer.
  • Cristian Suárez-Cabrera
  • Rita M Quintana
  • Ana Bravo
  • M Llanos Casanova
  • Angustias Page
  • Josefa P Alameda
  • Jesús M Paramio
  • Alicia Maroto
  • Javier Salamanca
  • Adam J Dupuy
  • Angel Ramírez
  • Manuel Navarro
  • Cancer Res..2017 03;77(6):1357-1368. 0008-5472.CAN-16-1586. doi: 10.1158/0008-5472.CAN-16-1586.Epub 2017-01-20.

ノンコーディングRNAの転写は、染色体トポロジーを変化させ、アイソタイプ特異的なクラススイッチ組換えを促進する

Noncoding RNA transcription alters chromosomal topology to promote isotype-specific class switch recombination.
  • Gerson Rothschild
  • Wanwei Zhang
  • Junghyun Lim
  • Pankaj Kumar Giri
  • Brice Laffleur
  • Yiyun Chen
  • Mingyan Fang
  • Yuling Chen
  • Lekha Nair
  • Zhi-Ping Liu
  • Haiteng Deng
  • Lennart Hammarström
  • Jiguang Wang
  • Uttiya Basu
  • Sci Immunol.2020 02;5(44). eaay5864. doi: 10.1126/sciimmunol.aay5864.

軸索誘導分子はマウスの同所性膵臓腫瘍の神経周囲浸潤と転移を促進する

Axon Guidance Molecules Promote Perineural Invasion and Metastasis of Orthotopic Pancreatic Tumors in Mice.
  • Noelle R Jurcak
  • Agnieszka A Rucki
  • Stephen Muth
  • Elizabeth Thompson
  • Rajni Sharma
  • Ding Ding
  • Qingfeng Zhu
  • James R Eshleman
  • Robert A Anders
  • Elizabeth M Jaffee
  • Kenji Fujiwara
  • Lei Zheng
  • Gastroenterology.2019 09;157(3):838-850.e6. S0016-5085(19)40983-9. doi: 10.1053/j.gastro.2019.05.065.Epub 2019-06-01.

オクタ-ベタインエステル多面体オリゴマーシルセスキオキサンをベースとした抗菌性および分解性ハイブリッドヒドロゲルに向けたクリック化学的アプローチ

Click-Chemistry Approach towards Antibacterial and Degradable Hybrid Hydrogels Based on Octa-Betaine Ester Polyhedral Oligomeric Silsesquioxane.
  • Jin Han
  • Qinyue Chen
  • Yupeng Sheng
  • Zhixiong Liu
  • Xiaoyu Hao
  • Mingqiang Zhong
  • Michael R Bockstaller
  • Biomacromolecules.2020 Jul;doi: 10.1021/acs.biomac.0c00530.Epub 2020-07-20.

ペチュニアのストリゴラクトン受容体DAD2の柔軟性は、シグナル伝達パートナーとの相互作用を促進する

Flexibility of the petunia strigolactone receptor DAD2 promotes its interaction with signaling partners.
  • Hui Wen Lee
  • Prachi Sharma
  • Bart J Janssen
  • Revel S M Drummond
  • Zhiwei Luo
  • Cyril Hamiaux
  • Thomas Collier
  • Jane R Allison
  • Richard D Newcomb
  • Kimberley C Snowden
  • J. Biol. Chem..2020 Mar;295(13):4181-4193. RA119.011509. doi: 10.1074/jbc.RA119.011509.Epub 2020-02-17.

急性呼吸器疾患のケアを求める患者におけるワクチン接種率の変動．システマティックレビューとメタアナリシス

Varying Vaccination Rates Among Patients Seeking Care for Acute Respiratory Illness: A Systematic Review and Meta-analysis.
  • Fadi Shehadeh
  • Ioannis M Zacharioudakis
  • Markos Kalligeros
  • Evangelia K Mylona
  • Tanka Karki
  • Robertus van Aalst
  • Ayman Chit
  • Eleftherios Mylonakis
  • Open Forum Infect Dis.2020 Jul;7(7):ofaa234. ofaa234. doi: 10.1093/ofid/ofaa234.Epub 2020-06-19.

TRPM5はリポ多糖刺激Bリンパ球のカルシウム依存性応答を負に制御する

TRPM5 Negatively Regulates Calcium-Dependent Responses in Lipopolysaccharide-Stimulated B Lymphocytes.
  • Taiki Sakaguchi
  • Ryu Okumura
  • Chisato Ono
  • Daisuke Okuzaki
  • Takafumi Kawai
  • Yoshifumi Okochi
  • Natsuko Tanimura
  • Mari Murakami
  • Hisako Kayama
  • Eiji Umemoto
  • Hidetaka Kioka
  • Tomohito Ohtani
  • Yasushi Sakata
  • Kensuke Miyake
  • Yasushi Okamura
  • Yoshihiro Baba
  • Kiyoshi Takeda
  • Cell Rep.2020 Jun;31(10):107755. S2211-1247(20)30735-X. doi: 10.1016/j.celrep.2020.107755.

ヘテロアリールベースの1,2,4-トリアゾールおよび1,3,4-オキサジアゾール誘導体の設計、合成および抗トリパノゾーマ活性

Design, synthesis and antitrypanosomal activity of heteroaryl-based 1,2,4-triazole and 1,3,4-oxadiazole derivatives.
  • Montaser Sh Shaykoon
  • Adel A Marzouk
  • Osama M Soltan
  • Amira S Wanas
  • Mohamed M Radwan
  • Ahmed M Gouda
  • Bahaa G M Youssif
  • Mohamed Abdel-Aziz
  • Bioorg. Chem..2020 Jul;100:103933. S0045-2068(20)30376-X. doi: 10.1016/j.bioorg.2020.103933.Epub 2020-05-15.

筋緊張性ジストロフィー1型 OPTIMISTICコホートにおける疾患重症度の遺伝的決定因子

Genetic determinants of disease severity in the myotonic dystrophy type 1 OPTIMISTIC cohort.
  • Sarah A Cumming
  • Cecilia Jimenez-Moreno
  • Kees Okkersen
  • Stephan Wenninger
  • Ferroudja Daidj
  • Fiona Hogarth
  • Roberta Littleford
  • Gráinne Gorman
  • Guillaume Bassez
  • Benedikt Schoser
  • Hanns Lochmüller
  • Baziel G M van Engelen
  • Darren G Monckton
  • Neurology.2019 09;93(10):e995-e1009. WNL.0000000000008056. doi: 10.1212/WNL.0000000000008056.Epub 2019-08-08.

コロナウイルス感染症（COVID-19）における頭頸部地区の症状。SARS-CoV-2の神経侵襲作用の可能性

Symptomatology in head and neck district in coronavirus disease (COVID-19): A possible neuroinvasive action of SARS-CoV-2.
  • Francesco Freni
  • Alessandro Meduri
  • Francesco Gazia
  • Viviana Nicastro
  • Cosimo Galletti
  • Pasquale Aragona
  • Cosimo Galletti
  • Bruno Galletti
  • Francesco Galletti
  • Am J Otolaryngol.2020 Jun;41(5):102612. S0196-0709(20)30306-9. doi: 10.1016/j.amjoto.2020.102612.Epub 2020-06-18.

頭頸部放射線治療中の患者の短期経過観察における唾液の流れと組成、口腔乾燥、QOLに対する光生物学的調節の効果：無作為化比較臨床試験

Effect of photobiomodulation on salivary flow and composition, xerostomia and quality of life of patients during head and neck radiotherapy in short term follow-up: A randomized controlled clinical trial.
  • Gabriel Campos Louzeiro
  • Karen Cherubini
  • Maria Antonia Zancanaro de Figueiredo
  • Fernanda Gonçalves Salum
  • J. Photochem. Photobiol. B, Biol..2020 Jun;209:111933. S1011-1344(20)30383-3. doi: 10.1016/j.jphotobiol.2020.111933.Epub 2020-06-13.

回転アテローム切除を必要とする重症石灰化病変に対する耐久性ポリマー・エベロリムス溶出ステントと生体吸収性ポリマー・エベロリムス溶出ステントの新内膜反応の比較

Comparison of Neointimal Response between Durable-Polymer Everolimus-Eluting Stent and Bioabsorbable-Polymer Everolimus-Eluting Stent for Severely Calcified Lesions Requiring Rotational Atherectomy.
  • Yuji Matsuda
  • Takashi Ashikaga
  • Taro Sasaoka
  • Yu Hatano
  • Tomoyuki Umemoto
  • Tetsumin Lee
  • Taishi Yonetsu
  • Yasuhiro Maejima
  • Tetsuo Sasano
  • Int Heart J.2020 Jul;doi: 10.1536/ihj.19-648.Epub 2020-07-18.

酸性土壌のリンと硫黄のバイオアベイラビリティーに及ぼすホスホギ石膏、可溶性肥料、石灰添加の影響 ルツェルンの環境下でのリンと硫黄のバイオアベイラビリティーに及ぼす影響

Impacts of Phosphogypsum, Soluble Fertilizer and Lime Amendment of Acid Soils on the Bioavailability of Phosphorus and Sulphur Under Lucerne ().
  • Moussa Bouray
  • Jim Moir
  • Leo Condron
  • Niklas Lehto
  • Plants (Basel).2020 Jul;9(7). E883. doi: 10.3390/plants9070883.Epub 2020-07-13.

アゾレス諸島からのヨーロッパの野生ウサギの間のブドウ球菌。人獣共通感染症の潜在的な問題か？

Staphylococci among Wild European Rabbits from the Azores: A Potential Zoonotic Issue?
  • Margarida Sousa
  • Vanessa Silva
  • Adriana Silva
  • Nuno Silva
  • Jessica Ribeiro
  • MarÍa Teresa Tejedor-Junco
  • Rosa Capita
  • Nadia Safia Chenouf
  • Carlos Alonso-Calleja
  • Tiago M Rodrigues
  • Manuel LeitÃo
  • David GonÇalves
  • Manuela CaniÇa
  • Carmen Torres
  • Gilberto Igrejas
  • PatrÍcia Poeta
  • J. Food Prot..2020 Jul;83(7):1110-1114. 438522. doi: 10.4315/0362-028X.JFP-19-423.

SARS-CoV/SARS-CoV-2感染フェレット肺の短期・長期モデルにおける遺伝子シグネチャーの解析

Gene signatures of SARS-CoV/SARS-CoV-2-infected ferret lungs in short- and long-term models.
  • Hsin-Liang Liu
  • I-Jeng Yeh
  • Nam Nhut Phan
  • Yen-Hung Wu
  • Meng-Chi Yen
  • Jui-Hsiang Hung
  • Chung-Chieh Chiao
  • Chien-Fu Chen
  • Zhengda Sun
  • Jia-Zhen Jiang
  • Hui-Ping Hsu
  • Chih-Yang Wang
  • Ming-Derg Lai
  • Infect. Genet. Evol..2020 Jun;85:104438. S1567-1348(20)30269-0. doi: 10.1016/j.meegid.2020.104438.Epub 2020-06-29.

Oct4は、2,3,7,8 -テトラクロロベンゾ-p-ジオキシン（TCDD）による口蓋裂の誘発と間葉系細胞の増殖抑制に関与していることが示唆された

Oct4 plays a role in 2, 3, 7, 8 - tetrachlorobenzo-p-dioxin (TCDD) inducing cleft palate and inhibiting mesenchymal proliferation.
  • Yuchang Tao
  • Xiaozhuan Liu
  • Lingling Cui
  • Xinxin Liu
  • Yao Chen
  • Zhidong He
  • Mengmeng Ji
  • Zhan Gao
  • Ning Li
  • Zhongxiao Wan
  • Zengli Yu
  • Toxicology.2020 May;438:152444. S0300-483X(20)30083-4. doi: 10.1016/j.tox.2020.152444.Epub 2020-04-10.

心房細動患者における経口抗凝固療法の安全性と有効性に及ぼすポリファーマシーとP-糖タンパク質およびCYP3A4修飾薬の影響

Impact of Polypharmacy and P-Glycoprotein- and CYP3A4-Modulating Drugs on Safety and Efficacy of Oral Anticoagulation Therapy in Patients with Atrial Fibrillation.
  • Ralf E Harskamp
  • Martina Teichert
  • Wim A M Lucassen
  • Henk C P M van Weert
  • Renato D Lopes
  • Cardiovasc Drugs Ther.2019 10;33(5):615-623. 10.1007/s10557-019-06907-8. doi: 10.1007/s10557-019-06907-8.

粒子状物質による大気汚染、不顕性冠動脈および頸動脈動脈硬化症の存在と進行との関連。システマティックレビュー

Associations between particulate matter air pollution, presence and progression of subclinical coronary and carotid atherosclerosis: A systematic review.
  • Mohammad Hashim Jilani
  • Bridget Simon-Friedt
  • Tamer Yahya
  • Ali Younas Khan
  • Syed Z Hassan
  • Bita Kash
  • Ron Blankstein
  • Michael J Blaha
  • Salim S Virani
  • Sanjay Rajagopalan
  • Miguel Cainzos-Achirica
  • Khurram Nasir
  • Atherosclerosis.2020 Jul;306:22-32. S0021-9150(20)30325-7. doi: 10.1016/j.atherosclerosis.2020.06.018.Epub 2020-07-05.

グルタチオン-PEG化リポソームメチルプレドニゾロンの遊離メチルプレドニゾロンとの比較：ヒト初の試験での徐放特性とリンパ球減少の延長

Glutathione-PEGylated liposomal methylprednisolone in comparison to free methylprednisolone: slow release characteristics and prolonged lymphocyte depression in a first-in-human study.
  • K M S Kanhai
  • R G J A Zuiker
  • I Stavrakaki
  • W Gladdines
  • P J Gaillard
  • E S Klaassen
  • G J Groeneveld
  • Br J Clin Pharmacol.2018 05;84(5):1020-1028. doi: 10.1111/bcp.13525.Epub 2018-03-09.

桑の実エキスは血清HDL-コレステロールレベルを促進し、高コレステロール/コレステロール/コレステロール値の食事を与えられたラットにおける肝microRNA-33の発現を抑制する

Mulberry Fruit Extract Promotes Serum HDL-Cholesterol Levels and Suppresses Hepatic microRNA-33 Expression in Rats Fed High Cholesterol/Cholic Acid Diet.
  • Soojin Lee
  • Mak-Soon Lee
  • Eugene Chang
  • Yoonjin Lee
  • Jaerin Lee
  • Jiyeon Kim
  • Chong-Tai Kim
  • In-Hwan Kim
  • Yangha Kim
  • Nutrients.2020 May;12(5). E1499. doi: 10.3390/nu12051499.Epub 2020-05-21.

脾臓機能亢進症関連血小板減少症を有する癌患者の血小板数に対する部分脾動脈塞栓術の耐久性

Durability of partial splenic artery embolization on platelet counts for cancer patients with hypersplenism-related thrombocytopenia.
  • Ashley Hill
  • Ahmed Elakkad
  • Joshua Kuban
  • Sharjeel Sabir
  • Bruno Odisio
  • Steven Y Huang
  • Armeen Mahvash
  • Ethan Miller
  • Michael H Kroll
  • Michael Overman
  • Alda L Tam
  • Sanjay Gupta
  • Rahul A Sheth
  • Abdom Radiol (NY).2020 Apr;10.1007/s00261-020-02523-5. doi: 10.1007/s00261-020-02523-5.Epub 2020-04-20.

基材の疎水性は、再構成したワックス膜の形態学的特徴や、非イオン界面活性剤や殺虫剤との相互作用にどのように影響するのでしょうか？

How does substrate hydrophobicity affect the morphological features of reconstituted wax films and their interactions with nonionic surfactant and pesticide?
  • Xuzhi Hu
  • Elias Pambou
  • Haoning Gong
  • Mingrui Liao
  • Peter Hollowell
  • Huayang Liu
  • Weimiao Wang
  • Carlo Bawn
  • Jos Cooper
  • Mario Campana
  • Kun Ma
  • Peixun Li
  • John R P Webster
  • Faheem Padia
  • Gordon Bell
  • Jian R Lu
  • J Colloid Interface Sci.2020 Sep;575:245-253. S0021-9797(20)30491-4. doi: 10.1016/j.jcis.2020.04.043.Epub 2020-04-10.

このように、犬の甲状腺軸と副腎活動は、28日生存犬と非生存犬を対象としたコホート研究で、420頭の犬の甲状腺軸と副腎活動を調べた。420頭の犬を対象としたコホート研究

Thyroid axis and adrenal activity in 28 day survivor and nonsurvivor dogs involved in recent road traffic accidents: A cohort study of 420 dogs.
  • Marco Caldin
  • Paola Rocchi
  • Andrea Zoia
  • Angelica Botto
  • Giovanna Bertolini
  • Giovanni Zappa
  • Tommaso Furlanello
  • Res. Vet. Sci..2020 Jun;132:243-249. S0034-5288(20)30912-7. doi: 10.1016/j.rvsc.2020.06.021.Epub 2020-06-27.

山地で栽培された灌漑多年草マメ科飼料、イネ科飼料、およびbf飼料のin vitro消化率は、非繊維性炭水化物および植物二次化合物の上昇によって影響を受ける

In vitro digestibility of mountain-grown irrigated perennial legume, grass and forb forages is influenced by elevated non-fibrous carbohydrates and plant secondary compounds.
  • Yunhua Zhang
  • Jennifer W MacAdam
  • Juan J Villalba
  • Xin Dai
  • J. Sci. Food Agric..2020 Jul;doi: 10.1002/jsfa.10648.Epub 2020-07-06.

一過性陰嚢温熱症誘発マウスでは、光生体調節により精子形成が回復することが示された

Photobiomodulation restores spermatogenesis in the transient scrotal hyperthermia-induced mice.
  • Amirhosein Hasani
  • Amirreza Khosravi
  • Kimia Rahimi
  • Azar Afshar
  • Fatemeh Fadaei-Fathabadi
  • Amir Raoofi
  • Pourya Raee
  • Fakhroddin Aghajanpour
  • Abbas Aliaghaei
  • Shabnam Abdi
  • Mohsen Norouzian
  • Mohammad-Amin Abdollahifar
  • Life Sci..2020 Aug;254:117767. S0024-3205(20)30515-4. doi: 10.1016/j.lfs.2020.117767.Epub 2020-05-11.

血漿中のmiR-20a-5p発現は、男性不妊の非侵襲的診断バイオマーカーとしての可能性がある。パイロット研究

Blood plasma miR-20a-5p expression as a potential non-invasive diagnostic biomarker of male infertility: A pilot study.
  • Gianmartin Cito
  • Maria Elisabetta Coccia
  • Francesca Salvianti
  • Rossella Fucci
  • Rita Picone
  • Claudia Giachini
  • Andrea Cocci
  • Patrizia Falcone
  • Elisabetta Micelli
  • Pierangelo Verrienti
  • Andrea Minervini
  • Marco Carini
  • Pamela Pinzani
  • Alessandro Natali
  • Andrology.2020 May;doi: 10.1111/andr.12816.Epub 2020-05-14.

原発性自然気胸の外来管理：非盲検無作為化比較試験

Ambulatory management of primary spontaneous pneumothorax: an open-label, randomised controlled trial.
  • Rob J Hallifax
  • Edward McKeown
  • Parthipan Sivakumar
  • Ian Fairbairn
  • Christy Peter
  • Andrew Leitch
  • Matthew Knight
  • Andrew Stanton
  • Asim Ijaz
  • Stefan Marciniak
  • James Cameron
  • Amrithraj Bhatta
  • Kevin G Blyth
  • Raja Reddy
  • Marie-Clare Harris
  • Nadeem Maddekar
  • Steven Walker
  • Alex West
  • Magda Laskawiec-Szkonter
  • John P Corcoran
  • Stephen Gerry
  • Corran Roberts
  • John E Harvey
  • Nick Maskell
  • Robert F Miller
  • Najib M Rahman
  • Lancet.2020 Jul;396(10243):39-49. S0140-6736(20)31043-6. doi: 10.1016/S0140-6736(20)31043-6.

オピオイド使用障害およびその他の脆弱性を有する喫煙者におけるニコチン低減タバコへの反応におけるタバコ離脱の調査

Investigating tobacco withdrawal in response to reduced nicotine cigarettes among smokers with opioid use disorder and other vulnerabilities.
  • Joanna M Streck
  • Stacey C Sigmon
  • Jeffrey Priest
  • Cecilia L Bergeria
  • Danielle R Davis
  • John R Hughes
  • Andrea C Villanti
  • Jennifer W Tidey
  • Sarah H Heil
  • Diann E Gaalema
  • Maxine L Stitzer
  • Stephen T Higgins
  • Exp Clin Psychopharmacol.2020 Feb;2020-07541-001. doi: 10.1037/pha0000350.Epub 2020-02-06.

アクリル化ユードラギット® E POは、鼻腔内ドラッグデリバリーへの応用を目的とした、粘膜接着性を向上させた新規高分子賦形剤です

Acrylated Eudragit® E PO as a novel polymeric excipient with enhanced mucoadhesive properties for application in nasal drug delivery.
  • Natalia N Porfiryeva
  • Shamil F Nasibullin
  • Svetlana G Abdullina
  • Irina K Tukhbatullina
  • Rouslan I Moustafine
  • Vitaliy V Khutoryanskiy
  • Int J Pharm.2019 May;562:241-248. S0378-5173(19)30213-3. doi: 10.1016/j.ijpharm.2019.03.027.Epub 2019-03-14.

乳房切除術後の1ステージ即時乳房再建における患者満足度。プロテーゼ、LDMF、TRAM術式の多施設比較患者評価

Patient satisfaction in one-stage immediate breast reconstruction after mastectomy: A multi-center comparative patient evaluation of prosthesis, LDMF, and TRAM techniques.
  • Chuqi Lei
  • Lijie Xu
  • Feng Xu
  • Jie Li
  • Hongchuan Jiang
  • Shan Guan
  • Xiang Wang
  • Bing Wen
  • Jinfeng Li
  • Xiru Li
  • Cuizhi Geng
  • Jian Yin
  • Medicine (Baltimore).2020 May;99(22):e19991. 00005792-202005290-00012. doi: 10.1097/MD.0000000000019991.

特発性下部尿路機能障害における心理学的病的病因の評価を日常的に行うべきか。ICI-RS 2019年版？

Should we routinely assess psychological morbidities in idiopathic lower urinary tract dysfunction: ICI-RS 2019?
  • Tufan Tarcan
  • Caroline Selai
  • François Herve
  • Desiree Vrijens
  • Phillip P Smith
  • Apostolos Apostolidis
  • Jalesh N Panicker
  • Ruth Kirschner-Hermanns
  • Salvador Arlandis
  • Giovanni Mosiello
  • Roger Dmochowski
  • Linda Cardozo
  • Alexander von Gontard
  • Neurourol. Urodyn..2020 Jul;39 Suppl 3:S70-S79. doi: 10.1002/nau.24361.

植物プランクトンの開花は底生生物に有害なのか？アナベナ属とクロレラ属の幼虫に対する毒性の影響について

Can phytoplankton blooming be harmful to benthic organisms? The toxic influence of Anabaena sp. and Chlorella sp. on Chironomus riparius larvae.
  • Nikola Stanković
  • Ivana Kostić
  • Boris Jovanović
  • Dimitrija Savić-Zdravković
  • Sanja Matić
  • Jelena Bašić
  • Tatjana Cvetković
  • Jelica Simeunović
  • Djuradj Milošević
  • Sci. Total Environ..2020 Aug;729:138666. S0048-9697(20)32183-5. doi: 10.1016/j.scitotenv.2020.138666.Epub 2020-04-13.

先天性高インスリン症におけるオクトレオチド関連外分泌膵臓機能不全（EPI）

Octreotide-related exocrine pancreatic insufficiency (EPI) in congenital hyperinsulinism.
  • Purificación Ros-Pérez
  • Luz Golmayo
  • María L Cilleruelo
  • Carolina Gutiérrez
  • Patricia Celaya
  • Nerea Lacámara
  • Itziar Martínez-Badás
  • María Güemes
  • Jesús Argente
  • J. Pediatr. Endocrinol. Metab..2020 Jul;33(7):947-950. /j/jpem.2020.33.issue-7/jpem-2019-0565/jpem-2019-0565.xml. doi: 10.1515/jpem-2019-0565.

アンジオテンシン変換酵素阻害薬とアンジオテンシン受容体拮抗薬は脛骨動脈閉塞症における血管内再灌流術の転帰に影響を及ぼさない

Angiotensin converting enzyme inhibitors and angiotensin receptor blockers have no effect on the outcomes of endovascular revascularization in tibial arterial occlusive disease.
  • Amandeep Juneja
  • Saqib Zia
  • Aravinda Abeysekara
  • Sara Shams
  • Kuldeep Singh
  • Jonathan Schor
  • Jonathan Deitch
  • Vascul. Pharmacol..2020 Aug;131:106764. S1537-1891(20)30091-4. doi: 10.1016/j.vph.2020.106764.Epub 2020-07-03.

男性と女性の路上乞食のリプロダクティブ・ヘルスの課題と、ナイジェリアのイフェ・イジェサでの女性路上乞食によるリプロダクティブ・ヘルス・サービスの利用

Reproductive health challenges of male and female street beggars and use of reproductive health services by female street beggars in Ife-Ijesa, Nigeria.
  • Macellina Y Ijadunola
  • Ezeomu A Olotu
  • Moseme I Makhele
  • Jimoh A Audu
  • Moses G Longe
  • Soliu A Lawal
  • Eur J Contracept Reprod Health Care.2020 Jul;:1-6. doi: 10.1080/13625187.2020.1774537.Epub 2020-07-03.

一般的なCYP2D6、CYP2C9、およびCYP2C19遺伝子の変異、健康不安、および神経症は、自己報告された抗うつ薬の副作用とは関連していない

Common CYP2D6, CYP2C9, and CYP2C19 Gene Variants, Health Anxiety, and Neuroticism Are Not Associated With Self-Reported Antidepressant Side Effects.
  • Simran Maggo
  • Martin A Kennedy
  • Zoe A Barczyk
  • Allison L Miller
  • Julia J Rucklidge
  • Roger T Mulder
  • James A Foulds
  • Front Genet.2019;10:1199. doi: 10.3389/fgene.2019.01199.Epub 2019-11-26.

ドロメダリーラクダおよびアルパカにおける中東呼吸器症候群コロナウイルススパイクタンパクワクチンのアジュバントの有効性

Efficacy of an Adjuvanted Middle East Respiratory Syndrome Coronavirus Spike Protein Vaccine in Dromedary Camels and Alpacas.
  • Danielle R Adney
  • Lingshu Wang
  • Neeltje van Doremalen
  • Wei Shi
  • Yi Zhang
  • Wing-Pui Kong
  • Megan R Miller
  • Trenton Bushmaker
  • Dana Scott
  • Emmie de Wit
  • Kayvon Modjarrad
  • Nikolai Petrovsky
  • Barney S Graham
  • Richard A Bowen
  • Vincent J Munster
  • Viruses.2019 03;11(3). E212. doi: 10.3390/v11030212.Epub 2019-03-02.

HNRNPU の新規フレームシフト変異を有する患者で観察された，二相性発作と後期拡散低下を伴う急性脳症と片麻痺および難治性てんかんのエピソード．

An episode of acute encephalopathy with biphasic seizures and late reduced diffusion followed by hemiplegia and intractable epilepsy observed in a patient with a novel frameshift mutation in HNRNPU.
  • Shino Shimada
  • Hirokazu Oguni
  • Yui Otani
  • Aiko Nishikawa
  • Susumu Ito
  • Kaoru Eto
  • Tomoyuki Nakazawa
  • Keiko Yamamoto-Shimojima
  • Jun-Ichi Takanashi
  • Satoru Nagata
  • Toshiyuki Yamamoto
  • Brain Dev..2018 Oct;40(9):813-818. S0387-7604(18)30220-1. doi: 10.1016/j.braindev.2018.05.010.Epub 2018-05-29.

3 種類の異なるミルクバイオマーカーを用いたホルスタイン乳牛の生理的不均衡の予測

Predicting physiological imbalance in Holstein dairy cows by three different sets of milk biomarkers.
  • Leslie Foldager
  • Charlotte Gaillard
  • Martin T Sorensen
  • Torben Larsen
  • Elizabeth Matthews
  • Roisin O'Flaherty
  • Fiona Carter
  • Mark A Crowe
  • Clément Grelet
  • Mazdak Salavati
  • Miel Hostens
  • Klaus L Ingvartsen
  • Mogens A Krogh
  • Prev. Vet. Med..2020 Jun;179:105006. S0167-5877(19)30743-3. doi: 10.1016/j.prevetmed.2020.105006.Epub 2020-04-21.

3Dプリントによるカスタムメイドのグレノイドコンポーネント : 大規模なグレノイド破壊と同時にカフ関節症の患者さんのためのアレスキュー補綴オプション

[Custom-made glenoid component via 3D print : A rescue prosthetic option for patients with massive glenoid destruction and simultaneous cuff-arthropathy].
  • Pauline Schmauder
  • Tobias Kraus
  • Markus A Küper
  • Patrick Ziegler
  • Atesch Ateschrang
  • Ulrich Stöckle
  • Thomas Freude
  • Orthopade.2020 Mar;49(3):267-272. 10.1007/s00132-019-03841-3. doi: 10.1007/s00132-019-03841-3.

Ｔ濾胞ヘルパー細胞媒介のＩＬ-２１産生は、びまん性大細胞Ｂ細胞リンパ腫患者におけるＴ濾胞調節因子様細胞のＦｏｘｐ３発現を抑制する

T follicular helper cell-mediated IL-21 production suppresses FOXP3 expression of T follicular regulatory-like cells in diffuse large B cell lymphoma patients.
  • Xiaomei Ma
  • Jie Zha
  • Jixiang He
  • Longtian Chen
  • Jianqing Huang
  • Weihao Wu
  • Pan Tian
  • Bao-Hua Qian
  • Lian Yu
  • Yirong Jiang
  • Bing Xu
  • Hum. Immunol..2020 Jun;S0198-8859(20)30320-7. doi: 10.1016/j.humimm.2020.05.008.Epub 2020-06-10.

中央ヨーロッパのStrigeidae Railliet, 1919 (Trematoda: Strigeidida)。分子および比較形態学的解析により、Parastrigea robusta Szidat, 1928をStrigea Abildgaard, 1790に再分類したことが示唆された

Central European Strigeidae Railliet, 1919 (Trematoda: Strigeidida): Molecular and comparative morphological analysis suggests the reclassification of Parastrigea robusta Szidat, 1928 into Strigea Abildgaard, 1790.
  • Petr Heneberg
  • Jiljí Sitko
  • Miroslav Těšínský
  • Izabella Rząd
  • Jiří Bizos
  • Parasitol. Int..2018 Dec;67(6):688-701. S1383-5769(17)30506-8. doi: 10.1016/j.parint.2018.07.003.Epub 2018-07-09.

大規模骨欠損を有する脛骨骨折に対するOrthofix固定具を用いた二重レベル骨輸送と一重レベル骨輸送の有効性の比較

Efficacy comparison of double-level and single-level bone transport with Orthofix fixator for treatment of tibia fracture with massive bone defects.
  • Yang Li
  • Shi Shen
  • Qiaosu Xiao
  • Guan Wang
  • Huilin Yang
  • Heng Zhao
  • Benchao Shu
  • Naiqiang Zhuo
  • Int Orthop.2020 May;44(5):957-963. 10.1007/s00264-020-04503-2. doi: 10.1007/s00264-020-04503-2.Epub 2020-02-29.

下肢切断の参加者における冠平面歩行運動学を得るための2つの臨床的に実行可能な測定方法の再現性と識別妥当性

Reproducibility and discriminant validity of two clinically feasible measurement methods to obtain coronal plane gait kinematics in participants with a lower extremity amputation.
  • Ruud A Leijendekkers
  • Thomas J Hoogeboom
  • Gerben van Hinte
  • Lars Didden
  • Thomas Anijs
  • Maria W G Nijhuis-van der Sanden
  • Nico Verdonschot
  • PLoS ONE.2019;14(5):e0217046. PONE-D-18-02416. doi: 10.1371/journal.pone.0217046.Epub 2019-05-21.

中国の5家族における全ゲノムシークエンシングにより同定されたリー症候群における新規ECHS1変異：症例報告

Novel ECHS1 mutations in Leigh syndrome identified by whole-exome sequencing in five Chinese families: case report.
  • Dan Sun
  • Zhimei Liu
  • Yongchu Liu
  • Miaojuan Wu
  • Fang Fang
  • Xianbo Deng
  • Zhisheng Liu
  • Liang Song
  • Kei Murayama
  • Chunhua Zhang
  • Yuanyuan Zhu
  • BMC Med. Genet..2020 Jul;21(1):149. 10.1186/s12881-020-01083-1. doi: 10.1186/s12881-020-01083-1.Epub 2020-07-16.

長時間スカーインアジャー：細胞外マトリックス合成のバイオマーカーを用いた抗線維化療法のin vitroスクリーニングツール

Prolonged Scar-in-a-Jar: an in vitro screening tool for anti-fibrotic therapies using biomarkers of extracellular matrix synthesis.
  • Sarah Rank Rønnow
  • Rand Qais Dabbagh
  • Federica Genovese
  • Carmel B Nanthakumar
  • Vikki J Barrett
  • Robert B Good
  • Sarah Brockbank
  • Simon Cruwys
  • Henrik Jessen
  • Grith Lykke Sorensen
  • Morten Asser Karsdal
  • Diana Julie Leeming
  • Jannie Marie Bülow Sand
  • Respir. Res..2020 May;21(1):108. 10.1186/s12931-020-01369-1. doi: 10.1186/s12931-020-01369-1.Epub 2020-05-07.

新興汚染物質によるN-貧弱な廃水の汚染は、紫光栄養細菌の性能とその後の資源回収の可能性に影響を与えない

Contamination of N-poor wastewater with emerging pollutants does not affect the performance of purple phototrophic bacteria and the subsequent resource recovery potential.
  • I de Las Heras
  • R Molina
  • Y Segura
  • T Hülsen
  • M C Molina
  • N Gonzalez-Benítez
  • J A Melero
  • A F Mohedano
  • F Martínez
  • D Puyol
  • J. Hazard. Mater..2020 03;385:121617. S0304-3894(19)31571-7. doi: 10.1016/j.jhazmat.2019.121617.Epub 2019-11-05.

Feel4Diabetes healthy diet score：開発と臨床的妥当性の評価

Feel4Diabetes healthy diet score: development and evaluation of clinical validity.
  • Eeva Virtanen
  • Jemina Kivelä
  • Katja Wikström
  • Christina-Paulina Lambrinou
  • Pilar De Miguel-Etayo
  • Nele Huys
  • Katalin Vraukó-Tóth
  • Luis A Moreno
  • Natalya Usheva
  • Nevena Chakarova
  • Sándorné A Rado
  • Violeta Iotova
  • Konstantinos Makrilakis
  • Greet Cardon
  • Stavros Liatis
  • Yannis Manios
  • Jaana Lindström
  • BMC Endocr Disord.2020 May;20(Suppl 2):46. 10.1186/s12902-020-0521-x. doi: 10.1186/s12902-020-0521-x.Epub 2020-05-06.

ニワトリの絨毛アラント膜上に成長した腫瘍移植片は、機能的ガスチャレンジ下でMRIで明瞭に特徴づけられる

Tumor grafts grown on the chicken chorioallantoic membrane are distinctively characterized by MRI under functional gas challenge.
  • Conny F Waschkies
  • Fatma Kivrak Pfiffner
  • Dorothea M Heuberger
  • Marcel A Schneider
  • Yinghua Tian
  • Petra Wolint
  • Maurizio Calcagni
  • Pietro Giovanoli
  • Johanna Buschmann
  • Sci Rep.2020 May;10(1):7505. 10.1038/s41598-020-64290-z. doi: 10.1038/s41598-020-64290-z.Epub 2020-05-05.

生物学的データを数理モデルに統合することで、ヒトパピローマウイルスと子宮頸部腫瘍形成のダイナミクスと相互作用を探る

Exploring the dynamics and interplay of human papillomavirus and cervical tumorigenesis by integrating biological data into a mathematical model.
  • Wenting Wu
  • Lei Song
  • Yongtao Yang
  • Jianxin Wang
  • Hongtu Liu
  • Le Zhang
  • BMC Bioinformatics.2020 May;21(Suppl 7):152. 10.1186/s12859-020-3454-5. doi: 10.1186/s12859-020-3454-5.Epub 2020-05-05.

褐色さび病および接種手順によるライ麦（Secale cereale L.）におけるベンゾオキサジノイド含量の変化および関連遺伝子の発現

Changes in benzoxazinoid contents and the expression of the associated genes in rye (Secale cereale L.) due to brown rust and the inoculation procedure.
  • Magdalena Święcicka
  • Marta Dmochowska-Boguta
  • Wacław Orczyk
  • Agnieszka Grądzielewska
  • Anna Stochmal
  • Mariusz Kowalczyk
  • Leszek Bolibok
  • Monika Rakoczy-Trojanowska
  • PLoS ONE.2020;15(5):e0233807. PONE-D-20-03469. doi: 10.1371/journal.pone.0233807.Epub 2020-05-29.

地方分権化された文脈の中で、地区保健の意思決定がどのように形成されているか。マラウイ、ウガンダ、ガーナにおける質的調査

How district health decision-making is shaped within decentralised contexts: A qualitative research in Malawi, Uganda and Ghana.
  • Susan E Bulthuis
  • Maryse C Kok
  • Samuel Amon
  • Samuel Agyei Agyemang
  • Xavier Nsabagasani
  • Lifah Sanudi
  • Joanna Raven
  • Mairead Finn
  • Jana Gerold
  • Olivia Tulloch
  • Marjolein A Dieleman
  • Glob Public Health.2020 Jul;:1-16. doi: 10.1080/17441692.2020.1791213.Epub 2020-07-13.

NiSOの流出により、フィンランド西部の河川では4種の淡水ムール貝（保護種のUnio crassus Philipsson, 1788を含む）の間でさまざまな死亡率が発生している

NiSO spill inflicts varying mortality between four freshwater mussel species (including protected Unio crassus Philipsson, 1788) in a western Finnish river.
  • Jaakko Johannes Leppänen
  • Jouni Leinikki
  • Anna Väisänen
  • Environ. Pollut..2020 Jan;256:113402. S0269-7491(19)34633-0. doi: 10.1016/j.envpol.2019.113402.Epub 2019-10-16.

オランダにおけるパーキンソン病における大規模な GBA1 遺伝子フルスクリーニング

A Large-Scale Full GBA1 Gene Screening in Parkinson's Disease in the Netherlands.
  • Jonas M den Heijer
  • Valerie C Cullen
  • Marialuisa Quadri
  • Arnoud Schmitz
  • Dana C Hilt
  • Peter Lansbury
  • Henk W Berendse
  • Wilma D J van de Berg
  • Rob M A de Bie
  • Jeffrey M Boertien
  • Agnita J W Boon
  • M Fiorella Contarino
  • Jacobus J van Hilten
  • Jorrit I Hoff
  • Tom van Mierlo
  • Alex G Munts
  • Anne A van der Plas
  • Mirthe M Ponsen
  • Frank Baas
  • Danielle Majoor-Krakauer
  • Vincenzo Bonifati
  • Teus van Laar
  • Geert J Groeneveld
  • Mov. Disord..2020 Jul;doi: 10.1002/mds.28112.Epub 2020-07-02.

ヒラメ（Paralichthys olivaceus）のストレプトコッカス・インフルエンザ感染症に対するワクチン候補としての免疫原性タンパク質の同定と組換えPDHA1とGAPDHの評価

Identification of immunogenic proteins and evaluation of recombinant PDHA1 and GAPDH as potential vaccine candidates against Streptococcus iniae infection in flounder (Paralichthys olivaceus).
  • Xiuzhen Sheng
  • Min Liu
  • Haibo Liu
  • Xiaoqian Tang
  • Jing Xing
  • Wenbin Zhan
  • PLoS ONE.2018;13(5):e0195450. PONE-D-18-02505. doi: 10.1371/journal.pone.0195450.Epub 2018-05-30.

アモルファスホウ化コバルトナノシートに表面機能化カーボンナノファイバーを固定化した。電気化学センシングと酸素発生反応のための二機能性・高効率触媒

Amorphous cobalt boride nanosheets anchored surface-functionalized carbon nanofiber: An bifunctional and efficient catalyst for electrochemical sensing and oxygen evolution reaction.
  • Ramaraj Sukanya
  • Shen-Ming Chen
  • J Colloid Interface Sci.2020 Jul;580:318-331. S0021-9797(20)30914-0. doi: 10.1016/j.jcis.2020.07.037.Epub 2020-07-13.

コロナウイルス疾患2019流行時の体外膜酸素投与による院内搬送に関する検討：重症H1N1インフルエンザウイルス肺炎6例の体外膜酸素投与による搬送経験を踏まえて

[Study on the extracorporeal membrane oxygenation inter-hospital transport during coronavirus disease 2019 epidemic: based on the transport experience of 6 cases of severe H1N1 influenza virus pneumonia on extracorporeal membrane oxygenation].
  • Qiancheng Xu
  • Xiaogan Jiang
  • Tao Wang
  • Quan Zhou
  • Jun Wang
  • Peng Zhang
  • Shangzhi Yang
  • Hao Yan
  • Xiubin Tao
  • Weihua Lu
  • Zhonghua Wei Zhong Bing Ji Jiu Yi Xue.2020 Apr;32(4):430-434. doi: 10.3760/cma.j.cn121430-20200309-00413.

質量分析イメージングとLC/MSを用いて、ニーマンピック病C1欠損マウスの小脳ホスホイノシチドの減少を明らかにした

Mass spectrometry imaging and LC/MS reveal decreased cerebellar phosphoinositides in Niemann-Pick type C1-null mice.
  • Koralege C Pathmasiri
  • Melissa R Pergande
  • Fernando Tobias
  • Rima Rebiai
  • Avia Rosenhouse-Dantsker
  • Ernesto R Bongarzone
  • Stephanie M Cologna
  • J. Lipid Res..2020 Jul;61(7):1004-1013. jlr.RA119000606. doi: 10.1194/jlr.RA119000606.Epub 2020-05-05.

MATH-BTBタンパク質TaMAB2はユビキチンを含む病巣に蓄積し、ユビキチンプロテアソームの翻訳開始機構と相互作用することが知られている

The MATH-BTB Protein TaMAB2 Accumulates in Ubiquitin-Containing Foci and Interacts With the Translation Initiation Machinery in .
  • Nataša Bauer
  • Andreja Škiljaica
  • Nenad Malenica
  • Genadij Razdorov
  • Marija Klasić
  • Martina Juranić
  • Marko Močibob
  • Stefanie Sprunck
  • Thomas Dresselhaus
  • Dunja Leljak Levanić
  • Front Plant Sci.2019;10:1469. doi: 10.3389/fpls.2019.01469.Epub 2019-11-22.

遊牧から定住へと移行する都市化・半都市化したチベット人集団のメタボリックシンドロームと食事パターンとの関連

Metabolic syndrome and its relation to dietary patterns among a selected urbanised and semi-urbanised Tibetan population in transition from nomadic to settled living environment.
  • Wen Peng
  • Yan Liu
  • Maureen Malowany
  • Hongru Chen
  • Xiaodong Su
  • Yongnian Liu
  • Public Health Nutr.2020 Apr;:1-9. S1368980019004798. doi: 10.1017/S1368980019004798.Epub 2020-04-21.

筋ジストロフィー患者における心臓病および主要な有害心イベントに対するバイオマーカーの診断および予後の価値を評価する

Evaluating the Diagnostic and Prognostic Value of Biomarkers for Heart Disease and Major Adverse Cardiac Events in Patients With Muscular Dystrophy.
  • Anish Nikhanj
  • Bailey Miskew Nichols
  • Kaiming Wang
  • Zaeem A Siddiqi
  • Gavin Y Oudit
  • Eur Heart J Qual Care Clin Outcomes.2020 Jul;qcaa059. doi: 10.1093/ehjqcco/qcaa059.Epub 2020-07-20.

白血球テトラスパニンCD53はαインテグリンの動員を抑制し、マウスの細胞骨格のリモデリングとトランスミグレーションを促進する

Leukocyte Tetraspanin CD53 Restrains α Integrin Mobilization and Facilitates Cytoskeletal Remodeling and Transmigration in Mice.
  • Louisa Yeung
  • Jeremy M L Anderson
  • Janet L Wee
  • Maria C Demaria
  • Michaela Finsterbusch
  • Yuxin S Liu
  • Pam Hall
  • Brodie C Smith
  • Wendy Dankers
  • Kirstin D Elgass
  • Ian P Wicks
  • Hang Fai Kwok
  • Mark D Wright
  • Michael J Hickey
  • J. Immunol..2020 Jul;205(2):521-532. jimmunol.1901054. doi: 10.4049/jimmunol.1901054.Epub 2020-06-12.

ニーマンピック型C病の欠陥スフィンゴシンキナーゼ1を活性化剤で標的化すると、コレステロール蓄積が緩和される

Targeting defective sphingosine kinase 1 in Niemann-Pick type C disease with an activator mitigates cholesterol accumulation.
  • Jason Newton
  • Elisa N D Palladino
  • Cynthia Weigel
  • Michael Maceyka
  • Markus H Gräler
  • Can E Senkal
  • Ricardo D Enriz
  • Pavlina Marvanova
  • Josef Jampilek
  • Santiago Lima
  • Sheldon Milstien
  • Sarah Spiegel
  • J. Biol. Chem..2020 Jul;295(27):9121-9133. RA120.012659. doi: 10.1074/jbc.RA120.012659.Epub 2020-05-08.

SOAT1は膵臓癌におけるメバロネート経路依存性を促進する

SOAT1 promotes mevalonate pathway dependency in pancreatic cancer.
  • Tobiloba E Oni
  • Giulia Biffi
  • Lindsey A Baker
  • Yuan Hao
  • Claudia Tonelli
  • Tim D D Somerville
  • Astrid Deschênes
  • Pascal Belleau
  • Chang-Il Hwang
  • Francisco J Sánchez-Rivera
  • Hilary Cox
  • Erin Brosnan
  • Abhishek Doshi
  • Rebecca P Lumia
  • Kimia Khaledi
  • Youngkyu Park
  • Lloyd C Trotman
  • Scott W Lowe
  • Alexander Krasnitz
  • Christopher R Vakoc
  • David A Tuveson
  • J. Exp. Med..2020 Sep;217(9). e20192389. doi: 10.1084/jem.20192389.

英国の低リスク飲酒ガイドライン改訂版の発表と実施がアルコール消費に及ぼす影響：中断時系列分析から得られた知見

Effects on alcohol consumption of announcing and implementing revised UK low-risk drinking guidelines: findings from an interrupted time series analysis.
  • John Holmes
  • Emma Beard
  • Jamie Brown
  • Alan Brennan
  • Petra S Meier
  • Susan Michie
  • Abigail K Stevely
  • Laura Webster
  • Penny F Buykx
  • J Epidemiol Community Health.2020 Jul;jech-2020-213820. doi: 10.1136/jech-2020-213820.Epub 2020-07-19.

WATCHMAN植込み患者における血栓形成性の詳細な表現型と1年後の転帰。(TARGET-WATCHMAN)ケースコントロール試験

Detailed thrombogenicity phenotyping and 1 year outcomes in patients undergoing WATCHMAN implantation: (TARGET-WATCHMAN) a case-control study.
  • Matthew Sherwood
  • Kevin P Bliden
  • Leonard Ilkhanoff
  • Ganesh Venkataraman
  • Adam Strickberger
  • Sharam Yazdani
  • Robert McSwain
  • Haroon Rashid
  • Eliano P Navarese
  • Tracy Plummer
  • Wayne Batchelor
  • Rahul Chaudhary
  • Udaya S Tantry
  • Paul A Gurbel
  • J. Thromb. Thrombolysis.2020 Jun;10.1007/s11239-020-02205-5. doi: 10.1007/s11239-020-02205-5.Epub 2020-06-29.

南米ガラガラヘビの肺動脈に沿ったコリン作動性の調節：血管反応性、ムスカリン受容体、迷走神経支配

Cholinergic regulation along the pulmonary arterial tree of the South American rattlesnake: vascular reactivity, muscarinic receptors, and vagal innervation.
  • Renato Filogonio
  • Marina Rincon Sartori
  • Susie Morgensen
  • Driele Tavares
  • Rafael Campos
  • Augusto S Abe
  • Edwin W Taylor
  • Gerson Jhonatan Rodrigues
  • Gilberto De Nucci
  • Ulf Simonsen
  • Cléo A C Leite
  • Tobias Wang
  • Am. J. Physiol. Regul. Integr. Comp. Physiol..2020 Jun;doi: 10.1152/ajpregu.00310.2019.Epub 2020-06-17.

骨髄由来の神経幹細胞をオリゴデンドロサイト様細胞に分化させるためのバイオインスパイアされたナノファイバー足場。設計、作製、および特性評価

Bioinspired Nanofiber Scaffold for Differentiating Bone Marrow-Derived Neural Stem Cells to Oligodendrocyte-Like Cells: Design, Fabrication, and Characterization.
  • Fatemeh Rasti Boroojeni
  • Shohreh Mashayekhan
  • Hojjat-Allah Abbaszadeh
  • Mohamadhasan Ansarizadeh
  • Maryam-Sadat Khoramgah
  • Vafa Rahimi Movaghar
  • Int J Nanomedicine.2020;15:3903-3920. 248509. doi: 10.2147/IJN.S248509.Epub 2020-06-02.

脳アミロイド血管症，アルツハイマー病，軽度認知障害における脳血管反応性

Cerebrovascular reactivity in cerebral amyloid angiopathy, Alzheimer disease, and mild cognitive impairment.
  • Aaron R Switzer
  • Ikreet Cheema
  • Cheryl R McCreary
  • Angela Zwiers
  • Anna Charlton
  • Ana Alvarez-Veronesi
  • Ramnik Sekhon
  • Charlotte Zerna
  • Randall B Stafford
  • Richard Frayne
  • Bradley G Goodyear
  • Eric E Smith
  • Neurology.2020 Jul;10.1212/WNL.0000000000010201. doi: 10.1212/WNL.0000000000010201.Epub 2020-07-08.

脳室内プロピオン酸誘発自閉症モデルにおけるソラネソールの神経保護効果。認知症モデルにおけるソラネソールの神経保護能：行動学的・生化学的エビデンスからの洞察

Neuroprotective potential of solanesol in intracerebroventricular propionic acid induced experimental model of autism: Insights from behavioral and biochemical evidence.
  • Ramit Sharma
  • Saloni Rahi
  • Sidharth Mehan
  • Toxicol Rep.2019;6:1164-1175. S2214-7500(19)30361-0. doi: 10.1016/j.toxrep.2019.10.019.Epub 2019-11-05.

COVID-19のアウトカム改善に向けた食事療法の機能的役割．仕事の仮説

Functional Role of Dietary Intervention to Improve the Outcome of COVID-19: A Hypothesis of Work.
  • Giovanni Messina
  • Rita Polito
  • Vincenzo Monda
  • Luigi Cipolloni
  • Nunzio Di Nunno
  • Giulio Di Mizio
  • Paolo Murabito
  • Marco Carotenuto
  • Antonietta Messina
  • Daniela Pisanelli
  • Anna Valenzano
  • Giuseppe Cibelli
  • Alessia Scarinci
  • Marcellino Monda
  • Francesco Sessa
  • Int J Mol Sci.2020 Apr;21(9). E3104. doi: 10.3390/ijms21093104.Epub 2020-04-28.

コンピュータ支援によるリンパ節の体積とCT減衰量の3次元測定による肺癌の局所リンパ節転移の診断

Diagnosis of regional node metastases in lung cancer with computer-aided 3D measurement of the volume and CT-attenuation values of lymph nodes.
  • Yoshiyuki Takahashi
  • Shodayu Takashima
  • Tomoaki Hakucho
  • Chie Miyake
  • Daisuke Morimoto
  • Bing-hu Jiang
  • Hodaka Numasaki
  • Yasuhiko Tomita
  • Katsuyuki Nakanishi
  • Masahiko Higashiyama
  • Acad Radiol.2013 Jun;20(6):740-5. S1076-6332(13)00035-4. doi: 10.1016/j.acra.2013.01.013.Epub 2013-03-06.

オーキシンの恒常性に関与するアミノトランスフェラーゼ遺伝子の機能喪失は、ソランナ科植物のパルテノカルピーを誘導する

Loss of function of the aminotransferase gene, which is involved in auxin homeostasis, induces parthenocarpy in Solanaceae plants.
  • Satoshi Matsuo
  • Koji Miyatake
  • Makoto Endo
  • Soichi Urashimo
  • Takaaki Kawanishi
  • Satomi Negoro
  • Satoshi Shimakoshi
  • Hiroyuki Fukuoka
  • Proc. Natl. Acad. Sci. U.S.A..2020 Jun;117(23):12784-12790. 2001211117. doi: 10.1073/pnas.2001211117.Epub 2020-05-27.

使用済みコーヒー挽き肉とコーヒー銀皮から得られた異なる抽出物の化学組成、抗酸化作用および酵素阻害作用

Chemical Composition, Antioxidant and Enzyme Inhibitory Properties of Different Extracts Obtained from Spent Coffee Ground and Coffee Silverskin.
  • Gokhan Zengin
  • Kouadio Ibrahime Sinan
  • Mohamad Fawzi Mahomoodally
  • Simone Angeloni
  • Ahmed M Mustafa
  • Sauro Vittori
  • Filippo Maggi
  • Giovanni Caprioli
  • Foods.2020 Jun;9(6). E713. doi: 10.3390/foods9060713.Epub 2020-06-02.

微小環境駆動型CD44アイソフォーム発現の可塑性がCRC細胞株における移植と幹様表現型を決定する

Microenvironmentally-driven Plasticity of CD44 isoform expression determines Engraftment and Stem-like Phenotype in CRC cell lines.
  • Thiemo F Dinger
  • Oleg Chen
  • Claudia Dittfeld
  • Lydia Hetze
  • Melanie Hüther
  • Marit Wondrak
  • Steffen Löck
  • Wolfgang Eicheler
  • Georg Breier
  • Leoni A Kunz-Schughart
  • Theranostics.2020;10(17):7599-7621. thnov10p7599. doi: 10.7150/thno.39893.Epub 2020-06-18.

北イタリアのミラノに定期的に居住する移民のHIV-1組換え型

HIV-1 recombinant forms in immigrants regularly residing in Milan, northern Italy.
  • Sabrina Bagaglio
  • Caterina Uberti-Foppa
  • Caterina Sagnelli
  • Alessia Lai
  • Hamid Hasson
  • Stefania Salpietro
  • Emanuela Messina
  • Giulia Morsica
  • Chiara Zaffina
  • Antonello Sica
  • Adriano Lazzarin
  • Silvia Angeletti
  • Evangelista Sagnelli
  • Brian Foley
  • Massimo Ciccozzi
  • Infection.2020 May;10.1007/s15010-020-01434-3. doi: 10.1007/s15010-020-01434-3.Epub 2020-05-19.

RhoGEFとRhoGAP調節タンパク質のシステム解析により、インテグリン接着からの空間的に組織化されたRAC1シグナルを明らかにした

Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.
  • Paul M Müller
  • Juliane Rademacher
  • Richard D Bagshaw
  • Celina Wortmann
  • Carolin Barth
  • Jakobus van Unen
  • Keziban M Alp
  • Girolamo Giudice
  • Rebecca L Eccles
  • Louise E Heinrich
  • Patricia Pascual-Vargas
  • Marta Sanchez-Castro
  • Lennart Brandenburg
  • Geraldine Mbamalu
  • Monika Tucholska
  • Lisa Spatt
  • Maciej T Czajkowski
  • Robert-William Welke
  • Sunqu Zhang
  • Vivian Nguyen
  • Trendelina Rrustemi
  • Philipp Trnka
  • Kiara Freitag
  • Brett Larsen
  • Oliver Popp
  • Philipp Mertins
  • Anne-Claude Gingras
  • Frederick P Roth
  • Karen Colwill
  • Chris Bakal
  • Olivier Pertz
  • Tony Pawson
  • Evangelia Petsalaki
  • Oliver Rocks
  • Nat. Cell Biol..2020 04;22(4):498-511. 10.1038/s41556-020-0488-x. doi: 10.1038/s41556-020-0488-x.Epub 2020-03-23.

選択的分解は、NPC1 変異細胞のエンドリゾソームにおけるアネキシン A6 とコレステロールレベルを制御するフィードバックループを可能にする

Selective Degradation Permits a Feedback Loop Controlling Annexin A6 and Cholesterol Levels in Endolysosomes of NPC1 Mutant Cells.
  • Elsa Meneses-Salas
  • Ana García-Melero
  • Patricia Blanco-Muñoz
  • Jaimy Jose
  • Marie-Sophie Brenner
  • Albert Lu
  • Francesc Tebar
  • Thomas Grewal
  • Carles Rentero
  • Carlos Enrich
  • Cells.2020 May;9(5). E1152. doi: 10.3390/cells9051152.Epub 2020-05-07.

ヒトおよびイヌのデュシェンヌ型およびベッカー型筋ジストロフィーにおける血漿脂質異常の高有病率は，新しいタイプの原発性遺伝性脂質異常症を描いている．

High prevalence of plasma lipid abnormalities in human and canine Duchenne and Becker muscular dystrophies depicts a new type of primary genetic dyslipidemia.
  • Zoe White
  • Chady H Hakim
  • Marine Theret
  • N Nora Yang
  • Fabio Rossi
  • Dan Cox
  • Gordon A Francis
  • Volker Straub
  • Kathryn Selby
  • Constadina Panagiotopoulos
  • Dongsheng Duan
  • Pascal Bernatchez
  • J Clin Lipidol.2020 May;S1933-2874(20)30196-3. doi: 10.1016/j.jacl.2020.05.098.Epub 2020-05-29.

心的外傷後ストレス障害およびオピオイド使用障害を有する退役軍人の全国コホートにおける薬物支援療法サービスの提供と死亡率との関連

Associations between Medication Assisted Therapy Services Delivery and Mortality in a National Cohort of Veterans with Posttraumatic Stress Disorder and Opioid Use Disorder.
  • Natalie B Riblet
  • Daniel J Gottlieb
  • Brian Shiner
  • Sarah L Cornelius
  • Bradley V Watts
  • J Dual Diagn.2020 Apr-Jun;16(2):228-238. doi: 10.1080/15504263.2019.1701218.Epub 2019-12-18.

食道扁平上皮癌細胞におけるMiR-498を介した細胞分裂周期42（CDC42）の発現制御を通じて、ロングノンコーディングRNAタウリンアップレギュレート遺伝子1（TUG1）のダウンレギュレーションが細胞の増殖と浸潤を抑制する

Long Non-Coding RNA Taurine Upregulated Gene 1 (TUG1) Downregulation Constrains Cell Proliferation and Invasion through Regulating Cell Division Cycle 42 (CDC42) Expression Via MiR-498 in Esophageal Squamous Cell Carcinoma Cells.
  • Zhifeng Wang
  • Jingmei Liu
  • Rong Wang
  • Qinqin Wang
  • Rong Liang
  • Jinliang Tang
  • Med. Sci. Monit..2020 Mar;26:e919714. 919714. doi: 10.12659/MSM.919714.Epub 2020-03-06.

コアシェル型パラジウム/MOFプラットフォームを用いた生体細胞および組織モデルにおける拡散制御ナノリアクターの開発

Core-Shell Palladium/MOF Platforms as Diffusion-Controlled Nanoreactors in Living Cells and Tissue Models.
  • Raquel Martínez
  • Carolina Carrillo-Carrión
  • Paolo Destito
  • Aitor Alvarez
  • María Tomás-Gamasa
  • Beatriz Pelaz
  • Fernando Lopez
  • José L Mascareñas
  • Pablo Del Pino
  • Cell Rep Phys Sci.2020 Jun;1(6):100076. S2666-3864(20)30071-0. doi: 10.1016/j.xcrp.2020.100076.Epub 2020-06-24.

臨床情報学は COVID-19 パンデミックへの医療システムの適応を加速させます。コロラド州の例

Clinical Informatics Accelerates Health System Adaptation to the COVID-19 Pandemic: Examples from Colorado.
  • Chen-Tan Lin
  • Kelly Bookman
  • Amber Sieja
  • Katie Markley
  • Richard L Altman
  • Jeffrey Sippel
  • Katharine Perica
  • Lori Reece
  • Christopher Davis
  • Edward Horowitz
  • Larissa Pisney
  • Peter D Sottile
  • David Kao
  • Bonnie Adrian
  • Melissa Szkil
  • Julie Griffin
  • Jeanie Youngwerth
  • Brendan Drew
  • Jonathan Pell
  • J Am Med Inform Assoc.2020 Jul;ocaa171. doi: 10.1093/jamia/ocaa171.Epub 2020-07-20.

Streptococcus agalactiae 感染に応答するナイルティラピア（Oreochromis niloticus）における CD2AP の分子クローニング、特徴、および発現プロファイル、および CD2 細胞質セグメントとの相互作用

Molecular cloning, characterization and expression profiles of CD2AP in Nile tilapia (Oreochromis niloticus) responding to Streptococcus agalactiae infection and interaction with CD2 cytoplasmic segment.
  • Yuan Li
  • Bei Wang
  • Zhi-Wen Wang
  • Yu Huang
  • Ji-Chang Jian
  • Yi-Shan Lu
  • Fish Shellfish Immunol..2020 Jun;101:205-215. S1050-4648(20)30222-9. doi: 10.1016/j.fsi.2020.03.054.Epub 2020-04-01.

テクスチャードインプラントを禁止することは、乳房インプラント関連未分化大細胞リンパ腫（BIA-ALCL）のリスクを排除するための合理的な判断である」への反応

Response to "Banning Textured Implants Is a Rational Decision to Eliminate the Risk of Breast Implant-Associated Anaplastic Large-Cell Lymphoma (BIA-ALCL)".
  • Stefan V Danilla
  • Rocio P Jara
  • Felipe Miranda
  • Francisco Bencina
  • Marcela Aguirre
  • Ekaterina Troncoso
  • Cristian A Erazo
  • Patricio R Andrades
  • Sergio L Sepulveda
  • Claudia R Albornoz
  • Aesthet Surg J.2020 Jul;40(8):NP478-NP479. 5866855. doi: 10.1093/asj/sjaa108.

慢性シャーガス病を有する心臓移植患者における潜在的バイオマーカーとしての血漿由来細胞外小胞

Plasma-Derived Extracellular Vesicles as Potential Biomarkers in Heart Transplant Patient with Chronic Chagas Disease.
  • Nuria Cortes-Serra
  • Maria Tays Mendes
  • Clara Mazagatos
  • Joan Segui-Barber
  • Cameron C Ellis
  • Cristina Ballart
  • Ana Garcia-Alvarez
  • Montserrat Gállego
  • Joaquim Gascon
  • Igor C Almeida
  • María Jesús Pinazo
  • Carmen Fernandez-Becerra
  • Emerging Infect. Dis..2020 Aug;26(8):1846-1851. doi: 10.3201/eid2608.191042.

また、アルブミンと結合した非エステル化遊離脂肪酸の生理的変化は、このタンパク質のヘム/ビリルビン結合特性に決定的な影響を与えている。内因性生体分子を用いた比較、in vitro、分光学的研究

Physiological changes in the albumin-bound non-esterified free fatty acids critically influence heme/bilirubin binding properties of the protein: A comparative, in vitro, spectroscopic study using the endogenous biomolecules.
  • Mahtab Amoorahim
  • Mohammad Reza Ashrafi-Kooshk
  • Sajjad Esmaeili
  • Mohsen Shahlaei
  • Sajad Moradi
  • Reza Khodarahmi
  • Spectrochim Acta A Mol Biomol Spectrosc.2020 Jul;235:118298. S1386-1425(20)30276-6. doi: 10.1016/j.saa.2020.118298.Epub 2020-03-24.

ケニアの国立紹介病院におけるHIV感染児のイソニアジド予防療法の実施と完了に影響を与える要因：量的・質的混合研究

Factors affecting uptake and completion of isoniazid preventive therapy among HIV-infected children at a national referral hospital, Kenya: a mixed quantitative and qualitative study.
  • Serah Kajuju Ngugi
  • Peter Muiruri
  • Theresa Odero
  • Onesmus Gachuno
  • BMC Infect. Dis..2020 Apr;20(1):294. 10.1186/s12879-020-05011-9. doi: 10.1186/s12879-020-05011-9.Epub 2020-04-21.

間欠的な低温刺激の筋におけるCREBとその標的遺伝子への影響：局所凍結療法の分子機構の解明

Influence of Intermittent Cold Stimulations on CREB and Its Targeting Genes in Muscle: Investigations into Molecular Mechanisms of Local Cryotherapy.
  • Takehito Sugasawa
  • Yoshiya Tome
  • Yoshinori Takeuchi
  • Yasuko Yoshida
  • Naoya Yahagi
  • Rahul Sharma
  • Yuichi Aita
  • Haruna Ueda
  • Reina Maruyama
  • Kaoru Takeuchi
  • Shohei Morita
  • Yasushi Kawamai
  • Kazuhiro Takekoshi
  • Int J Mol Sci.2020 Jun;21(13). E4588. doi: 10.3390/ijms21134588.Epub 2020-06-28.

BRCA2およびCHEK2遺伝子の二重ヘテロ接合性生殖細胞変異を有する転移性膵腺癌における化学療法の完全奏効 - 症例報告

Complete Response to Chemotherapy in Metastatic Pancreatic Carcinoma Associated with Double Heterozygous Germline Mutation in BRCA2 and CHEK2 Genes - a Case Report.
  • Natália Pazderová
  • Veronika Urbán
  • Marek Makovník
  • Dušan Macák
  • Pavol Janega
  • Michal Chovanec
  • Katarína Rejleková
  • Jozef Mardiak
  • Michal Mego
  • Klin Onkol.2020;33(3):220-225. 123023. doi: 10.14735/amko2020220.

モノカルボン酸トランスポーター1は、6-ホスホフルクト-2-キナーゼ/フルクトース-2,6-ビホスファターゼ3を介して、古典的なミクログリアの活性化と炎症促進作用を促進する

Monocarboxylate transporter 1 promotes classical microglial activation and pro-inflammatory effect via 6-phosphofructo-2-kinase/fructose-2, 6-biphosphatase 3.
  • Liang Kong
  • Zehua Wang
  • Xiaohong Liang
  • Yue Wang
  • Lifen Gao
  • Chunhong Ma
  • J Neuroinflammation.2019 Nov;16(1):240. 10.1186/s12974-019-1648-4. doi: 10.1186/s12974-019-1648-4.Epub 2019-11-28.

市中肺炎で入院した患者の誤嚥リスク因子、微生物学的検査、経験的抗生物質

Aspiration risk factors, microbiology and empiric antibiotics for patients hospitalized with community-acquired pneumonia.
  • Judith Marin-Corral
  • Sergi Pascual-Guardia
  • Amati Francesco
  • Stefano Aliberti
  • Joan R Masclans
  • Nilam Soni
  • Alejandro Rodriguez
  • Oriol Sibila
  • Francisco Sanz
  • Giovanni Sotgiu
  • Antonio Anzueto
  • Katerina Dimakou
  • Roberta Petrino
  • Ewoudt van de Garde
  • Marcos I Restrepo
  • Chest.2020 Jul;S0012-3692(20)31905-X. doi: 10.1016/j.chest.2020.06.079.Epub 2020-07-17.

AIMTOR、ライブイメージングのためのBRETバイオセンサーは、細胞内のmTORシグナル伝達と機能不全を明らかにする

AIMTOR, a BRET biosensor for live imaging, reveals subcellular mTOR signaling and dysfunctions.
  • Nathalie Bouquier
  • Enora Moutin
  • Lionel A Tintignac
  • Amandine Reverbel
  • Elodie Jublanc
  • Michael Sinnreich
  • Yan Chastagnier
  • Julien Averous
  • Pierre Fafournoux
  • Chiara Verpelli
  • Tobias Boeckers
  • Gilles Carnac
  • Julie Perroy
  • Vincent Ollendorff
  • BMC Biol..2020 Jul;18(1):81. 10.1186/s12915-020-00790-8. doi: 10.1186/s12915-020-00790-8.Epub 2020-07-03.

遺伝子CYP2C9およびVKORC1の非遺伝的因子および多型：ブラジルのワルファリン投与患者におけるTTRの予測アルゴリズム

Non-genetic factors and polymorphisms in genes CYP2C9 and VKORC1: predictive algorithms for TTR in Brazilian patients on warfarin.
  • Marcus Fernando S Praxedes
  • Maria Auxiliadora P Martins
  • Aline O M Mourão
  • Karina B Gomes
  • Edna A Reis
  • Renan P Souza
  • Emílio Itamar F Campos
  • Daniel D Ribeiro
  • Manoel Otávio C Rocha
  • Eur. J. Clin. Pharmacol..2020 Feb;76(2):199-209. 10.1007/s00228-019-02772-4. doi: 10.1007/s00228-019-02772-4.Epub 2019-11-12.

塩分濃度の異なる環境に適応したヨーロッパのシーバスDicentrarchus labraxにおける極端な環境温度の影響。生育成績、代謝および分子ストレス応答

Effects of extreme ambient temperature in European seabass, Dicentrarchus labrax acclimated at different salinities: Growth performance, metabolic and molecular stress responses.
  • Md Jakiul Islam
  • Andreas Kunzmann
  • Rajko Thiele
  • Matthew James Slater
  • Sci. Total Environ..2020 Sep;735:139371. S0048-9697(20)32888-6. doi: 10.1016/j.scitotenv.2020.139371.Epub 2020-05-14.

転写因子HAND2は、ヒト子宮内膜間質細胞における遺伝子の転写をアップレギュレートする

The transcription factor HAND2 up-regulates transcription of the gene in human endometrial stromal cells.
  • Hiromi Murata
  • Susumu Tanaka
  • Tomoko Tsuzuki-Nakao
  • Takeharu Kido
  • Maiko Kakita-Kobayashi
  • Naoko Kida
  • Yoji Hisamatsu
  • Hiroaki Tsubokura
  • Yoshiko Hashimoto
  • Masaaki Kitada
  • Hidetaka Okada
  • J. Biol. Chem..2020 Jul;295(28):9596-9605. RA120.012753. doi: 10.1074/jbc.RA120.012753.Epub 2020-05-22.

大豆ナッツバターに関連した O157:H7 感染症の多州合同アウトブレイク

A Multistate Outbreak of O157:H7 Infections Linked to Soy Nut Butter.
  • Rashida Hassan
  • Sharon Seelman
  • Vi Peralta
  • Hillary Booth
  • Mackenzie Tewell
  • Beth Melius
  • Brooke Whitney
  • Rosemary Sexton
  • Asha Dwarka
  • Duc Vugia
  • Jeff Vidanes
  • David Kiang
  • Elysia Gonzales
  • Natasha Dowell
  • Samantha M Olson
  • Lori M Gladney
  • Michael A Jhung
  • Karen P Neil
  • Pediatrics.2019 10;144(4). e20183978. doi: 10.1542/peds.2018-3978.Epub 2019-09-13.

本研究では、ニッケル置換Na2FeSiO4@C微小球をIn-situ合成したアルベオレーション様炭素マトリックスに内包させた場合の優れたNa貯蔵特性を明らかにした

Superior Na-Storage Properties of Nickel-Substituted Na2FeSiO4@C Microspheres Encapsulated with the In-Situ Synthesized Alveolation-Like Carbon Matrix.
  • Yansong Bai
  • Xiaoyan Zhang
  • Hongbo Shu
  • Zhigao Luo
  • Hai Hu
  • Qinglan Zhao
  • Ying Wang
  • Xianyou Wang
  • ACS Appl Mater Interfaces.2020 Jul;doi: 10.1021/acsami.0c07894.Epub 2020-07-13.

脱炭酸マール地の古代広葉樹林における表土の特性と控え地の植物の多様性を促進する主な要因としてのリターの質と微地形

Litter quality and microtopography as key drivers to topsoil properties and understorey plant diversity in ancient broadleaved forests on decalcified marl.
  • A M Kooijman
  • H A Weiler
  • C Cusell
  • N Anders
  • X Meng
  • A C Seijmonsbergen
  • L H Cammeraat
  • Sci. Total Environ..2019 Sep;684:113-125. S0048-9697(19)32326-5. doi: 10.1016/j.scitotenv.2019.05.285.Epub 2019-05-21.

マキノフェノール抽出物は、PKC-αシグナル伝達経路を調節し、鉛(II)暴露マウスの小胞体ストレスを減少させることにより、肝機能を維持することが示された

Malus micromalus Makino phenolic extract preserves hepatorenal function by regulating PKC-α signaling pathway and attenuating endoplasmic reticulum stress in lead (II) exposure mice.
  • Guangliang Wang
  • Jinlei Tang
  • Qi Song
  • Qianqian Yu
  • Congying Yao
  • Pengfei Li
  • Yixin Ding
  • Mibin Lin
  • Dai Cheng
  • J. Inorg. Biochem..2020 02;203:110925. S0162-0134(19)30536-7. doi: 10.1016/j.jinorgbio.2019.110925.Epub 2019-11-14.

植物化学物質インディカキサンチンは、酸化ストレス依存性のp53/p21軸を介してHeLa細胞におけるシスプラチン誘発性アポトーシスを相乗的に増強する

The Phytochemical Indicaxanthin Synergistically Enhances Cisplatin-Induced Apoptosis in HeLa Cells via Oxidative Stress-Dependent p53/p21 Axis.
  • Mario Allegra
  • Antonella D'Anneo
  • Anna Frazzitta
  • Ignazio Restivo
  • Maria Antonia Livrea
  • Alessandro Attanzio
  • Luisa Tesoriere
  • Biomolecules.2020 Jul;10(7). E994. doi: 10.3390/biom10070994.Epub 2020-07-02.

メタボリックシンドロームとバターやケルマンシャーギーを含む乳由来の油の消費との関係。Ravansar非伝染性疾患コホート研究

Relationship Between the Consumption of Milk-Based Oils Including Butter and Kermanshah Ghee with Metabolic Syndrome: Ravansar Non-Communicable Disease Cohort Study.
  • Elham Ahmadi
  • Hadi Abdollahzad
  • Yahya Pasdar
  • Shahab Rezaeian
  • Jalal Moludi
  • Seyed Mostafa Nachvak
  • Roghayeh Mostafai
  • Diabetes Metab Syndr Obes.2020;13:1519-1530. 247412. doi: 10.2147/DMSO.S247412.Epub 2020-05-05.

新しい大気圧イオン化プローブ（UniSpray™）を用いたLC-MS/MSによる静脈全血からの免疫抑制剤の定量のための体積吸収型マイクロサンプリング（VAMS）

Volumetric Absorptive Microsampling (VAMS) for assaying immunosuppressants from venous whole blood by LC-MS/MS using a novel atmospheric pressure ionization probe (UniSpray™).
  • Lucía Paniagua-González
  • Carla Díaz-Louzao
  • Elena Lendoiro
  • Esteban Otero-Antón
  • Carmen Cadarso-Suárez
  • Manuel López-Rivadulla
  • Angelines Cruz
  • Ana de-Castro-Ríos
  • J Pharm Biomed Anal.2020 Jun;189:113422. S0731-7085(20)31308-X. doi: 10.1016/j.jpba.2020.113422.Epub 2020-06-12.

プロトンポンプ阻害剤パントプラゾールの腎臓・肝臓移植患者のマイコフェノール酸曝露に対する効果（IMPACT試験）：無作為化試験

Effect of the proton-pump Inhibitor pantoprazole on MycoPhenolic ACid exposure in kidney and liver transplant recipienTs (IMPACT study): a randomized trial.
  • Andrew Sunderland
  • Graeme Russ
  • Benedetta Sallustio
  • Matthew Cervelli
  • David Joyce
  • Esther Ooi
  • Gary Jeffrey
  • Neil Boudville
  • Aron Chakera
  • Gursharan Dogra
  • Doris Chan
  • Germaine Wong
  • Wai H Lim
  • Nephrol. Dial. Transplant..2020 Jun;35(6):1060-1070. 5855235. doi: 10.1093/ndt/gfaa111.

ユビキチン特異的プロテアーゼ12および13によるH2Aub1の除去は、シロイヌナズナにおいてポリコムを介した安定な遺伝子抑制に必要であることを明らかにした

Removal of H2Aub1 by ubiquitin-specific proteases 12 and 13 is required for stable Polycomb-mediated gene repression in Arabidopsis.
  • Lejon E M Kralemann
  • Shujing Liu
  • Minerva S Trejo-Arellano
  • Rafael Muñoz-Viana
  • Claudia Köhler
  • Lars Hennig
  • Genome Biol..2020 Jun;21(1):144. 10.1186/s13059-020-02062-8. doi: 10.1186/s13059-020-02062-8.Epub 2020-06-16.

von Willebrand factorの大きなインフレーム欠失の特徴を明らかにすることで、異なる発症機序が明らかになった

Characterization of large in-frame von Willebrand factor deletions highlights differing pathogenic mechanisms.
  • Ashley Cartwright
  • Simon J Webster
  • Annika de Jong
  • Richard J Dirven
  • Lisa D S Bloomer
  • Ahlam M Al-Buhairan
  • Ulrich Budde
  • Christer Halldén
  • David Habart
  • Jenny Goudemand
  • Ian R Peake
  • Jeroen C J Eikenboom
  • Anne C Goodeve
  • Daniel J Hampshire
  • Blood Adv.2020 Jul;4(13):2979-2990. 461228. doi: 10.1182/bloodadvances.2018027813.

この研究では、分子動力学とドッキングシミュレーションを組み合わせて、hTRPM8チャネル上で最適化されたバーチャルスクリーニングキャンペーンを実行するためのターゲットとなるプロトコルを開発した

Combining Molecular Dynamics and Docking Simulations to Develop Targeted Protocols for Performing Optimized Virtual Screening Campaigns on The hTRPM8 Channel.
  • Carmine Talarico
  • Silvia Gervasoni
  • Candida Manelfi
  • Alessandro Pedretti
  • Giulio Vistoli
  • Andrea R Beccari
  • Int J Mol Sci.2020 Mar;21(7). E2265. doi: 10.3390/ijms21072265.Epub 2020-03-25.

肺移植候補者における在宅ベースのプレハビリテーションプログラム参加中の 6 分間歩行距離の変化-レトロスペクティブなカルテレビュー

Changes in 6-minute walking distance in lung transplant candidates while participating in a home-based pre-habilitation program - A retrospective chart review.
  • Daniela Massierer
  • Nicholas Bourgeois
  • Agnès Räkel
  • Karina Prévost
  • Larry C Lands
  • Charles Poirier
  • Tania Janaudis-Ferreira
  • Clin Transplant.2020 Jul;:e14045. doi: 10.1111/ctr.14045.Epub 2020-07-19.

持続的薬物送達システムとしてのイブプロフェン-メソポーラスハイドロキシアパタイトナノハイブリッドの簡便な合成と特性評価

Facile Synthesis and Characterization of Ibuprofen-mesoporous Hydroxyapatite Nanohybrid as a Sustained Drug Delivery System.
  • Zahra Namazi
  • Tahereh Sadat Jafarzadeh Kashi
  • Mohammad Erfan
  • Farhood Najafi
  • Leila Bakhtiari
  • Seyed Rohola Ghodsi
  • Hassan Farhadnejad
  • Iran J Pharm Res.2019;18(3):1196-1211. doi: 10.22037/ijpr.2019.1100769.

Mitotic checkpoint kinase Mps1/TTKは大腸がん患者の予後を予測し、PKCα/ERK1/2やPI3K/Akt経路を介して腫瘍の増殖や分化を制御しています

Mitotic checkpoint kinase Mps1/TTK predicts prognosis of colon cancer patients and regulates tumor proliferation and differentiation via PKCα/ERK1/2 and PI3K/Akt pathway.
  • Li Zhang
  • Baofei Jiang
  • Ni Zhu
  • Mingyue Tao
  • Yali Jun
  • Xiaofei Chen
  • Qilong Wang
  • Chao Luo
  • Med. Oncol..2019 Nov;37(1):5. 10.1007/s12032-019-1320-y. doi: 10.1007/s12032-019-1320-y.Epub 2019-11-13.

FGFR4は肺腺癌におけるEGFRの癌化シグナルを増加させ、両者の複合的な阻害は高い効果を発揮する

FGFR4 increases EGFR oncogenic signaling in lung adenocarcinoma, and their combined inhibition is highly effective.
  • Alvaro Quintanal-Villalonga
  • Sonia Molina-Pinelo
  • Patricia Yagüe
  • Ángela Marrugal
  • Laura Ojeda-Márquez
  • Rocío Suarez
  • Santiago Ponce-Aix
  • Ana Belén Enguita
  • Amancio Carnero
  • Irene Ferrer
  • Luis Paz-Ares
  • Lung Cancer.2019 05;131:112-121. S0169-5002(19)30323-X. doi: 10.1016/j.lungcan.2019.02.007.Epub 2019-02-08.

枯草菌株NCD-2のPhoR/PhoP二成分系によって制御される多剤耐性を表現型マイクロアレイとトランスクリプトーム解析を用いて明らかにした

Using a phenotype microarray and transcriptome analysis to elucidate multi-drug resistance regulated by the PhoR/PhoP two-component system in Bacillus subtilis strain NCD-2.
  • Qinggang Guo
  • Lihong Dong
  • Peipei Wang
  • Zhenhe Su
  • Xiaomeng Liu
  • Weisong Zhao
  • Xiaoyun Zhang
  • Shezeng Li
  • Xiuyun Lu
  • Ping Ma
  • Microbiol. Res..2020 Jul;239:126557. S0944-5013(20)30425-0. doi: 10.1016/j.micres.2020.126557.Epub 2020-07-13.

最適化された全長 FLT3/CD3 ビスpecific 抗体は、強力な抗白血病活性を示し、可逆的な血液学的毒性を示します

An Optimized Full-Length FLT3/CD3 Bispecific Antibody Demonstrates Potent Anti-leukemia Activity and Reversible Hematological Toxicity.
  • Yik Andy Yeung
  • Veena Krishnamoorthy
  • Danielle Dettling
  • Cesar Sommer
  • Kris Poulsen
  • Irene Ni
  • Amber Pham
  • Wei Chen
  • Sindy Liao-Chan
  • Kevin Lindquist
  • S Michael Chin
  • Allison Given Chunyk
  • Wenyue Hu
  • Barbra Sasu
  • Javier Chaparro-Riggers
  • Ivana Djuretic
  • Mol. Ther..2020 03;28(3):889-900. S1525-0016(20)30009-5. doi: 10.1016/j.ymthe.2019.12.014.Epub 2020-01-14.

ビタミンB12のコバルト中心のニッケルによる置換-金属を含まないB12-リガンドHydrogenobalaminとHydrogenobyric Acidから調製されたニバラミンとニ酪酸

Replacement of the Cobalt-Center of Vitamin B12 by Nickel - Nibalamin and Nibyric Acid Prepared from Metal-Free B12-Ligands Hydrogenobalamin and Hydrogenobyric Acid.
  • Christoph Kieninger
  • Klaus Wurst
  • Maren Podewitz
  • Maria Stanley
  • Evelyne Deery
  • Anrew Lawrence
  • Klaus R Liedl
  • Martin J Warren
  • Bernhard Kräutler
  • Angew. Chem. Int. Ed. Engl..2020 Jul;doi: 10.1002/anie.202008407.Epub 2020-07-20.

クラインフェルター症候群とターナー症候群の統合的な機能ゲノム解析により、X染色体線量変化のグローバルなネットワーク効果が明らかになった

Integrated functional genomic analyses of Klinefelter and Turner syndromes reveal global network effects of altered X chromosome dosage.
  • Xianglong Zhang
  • David Hong
  • Shining Ma
  • Thomas Ward
  • Marcus Ho
  • Reenal Pattni
  • Zhana Duren
  • Atanas Stankov
  • Sharon Bade Shrestha
  • Joachim Hallmayer
  • Wing Hung Wong
  • Allan L Reiss
  • Alexander E Urban
  • Proc. Natl. Acad. Sci. U.S.A..2020 03;117(9):4864-4873. 1910003117. doi: 10.1073/pnas.1910003117.Epub 2020-02-18.

喉頭咽頭逆流症患者の食事の逆流性を評価するスコアの開発

Development of scores assessing the refluxogenic potential of diet of patients with laryngopharyngeal reflux.
  • Jerome R Lechien
  • Francois Bobin
  • Francois Mouawad
  • Karol Zelenik
  • Christian Calvo-Henriquez
  • Carlos M Chiesa-Estomba
  • Necati Enver
  • Andrea Nacci
  • Maria Rosaria Barillari
  • Antonio Schindler
  • Lise Crevier-Buchman
  • Stéphane Hans
  • Virginie Simeone
  • Elzbieta Wlodarczyk
  • Bernard Harmegnies
  • Marc Remacle
  • Alexandra Rodriguez
  • Didier Dequanter
  • Pierre Eisendrath
  • Giovanni Dapri
  • Camille Finck
  • Petros Karkos
  • Hillevi Pendleton
  • Tareck Ayad
  • Vinciane Muls
  • Sven Saussez
  • Eur Arch Otorhinolaryngol.2019 Dec;276(12):3389-3404. 10.1007/s00405-019-05631-1. doi: 10.1007/s00405-019-05631-1.Epub 2019-09-12.

PGC1αはPDHA1とMPC1の発現をアップレギュレーションすることで胆管癌の転移を促進し、Warburg効果を逆転させる

PGC1α promotes cholangiocarcinoma metastasis by upregulating PDHA1 and MPC1 expression to reverse the Warburg effect.
  • Dan Li
  • Chaoqun Wang
  • Panfei Ma
  • Qingan Yu
  • Mingqi Gu
  • Liqian Dong
  • Wenjing Jiang
  • Shangha Pan
  • Changming Xie
  • Jihua Han
  • Yaliang Lan
  • Jing Sun
  • Ping Sheng
  • Kunpeng Liu
  • Yaohua Wu
  • Lianxin Liu
  • Yong Ma
  • Hongchi Jiang
  • Cell Death Dis.2018 05;9(5):466. 10.1038/s41419-018-0494-0. doi: 10.1038/s41419-018-0494-0.Epub 2018-05-01.

非硬直性隔壁静脈血栓症の診断における次世代シーケンシング

Next generation sequencing in the diagnosis of non-cirrhotic splanchnic vein thrombosis.
  • Marta Magaz
  • Alberto Alvarez-Larrán
  • Dolors Colomer
  • Mónica López-Guerra
  • M Ángeles García-Criado
  • Gabriel Mezzano
  • Ernest Belmonte
  • Pol Olivas
  • Guillem Soy
  • Francisco Cervantes
  • Anna Darnell
  • José Ferrusquía-Acosta
  • Anna Baiges
  • Fanny Turon
  • Virginia Hernández-Gea
  • Juan Carlos García-Pagán
  • J. Hepatol..2020 Jul;S0168-8278(20)30456-6. doi: 10.1016/j.jhep.2020.06.045.Epub 2020-07-14.

ヒト誘導多能性幹細胞由来心筋細胞を用いた収縮運動特性に対する薬物誘発効果のビデオベースの評価

Video-based assessment of drug-induced effects on contractile motion properties using human induced pluripotent stem cell-derived cardiomyocytes.
  • Yoshiko Okai
  • Keiko Matsune
  • Kazunori Yamanaka
  • Toshikatsu Matsui
  • Emily Pfeiffer Kaushik
  • Kosuke Harada
  • Hiroshi Kohara
  • Akimitsu Miyawaki
  • Harushige Ozaki
  • Matthew Wagoner
  • Tadahiro Shinozawa
  • J Pharmacol Toxicol Methods.2020 Jul;:106893. S1056-8719(20)30222-7. doi: 10.1016/j.vascn.2020.106893.Epub 2020-07-01.

発酵飼料とワクチン接種と大型ホワイト/ノルウェーランドレース子豚のパラメータに及ぼす影響とその相互作用

Influence of the Fermented Feed and Vaccination and Their Interaction on Parameters of Large White/Norwegian Landrace Piglets.
  • Laurynas Vadopalas
  • Sarunas Badaras
  • Modestas Ruzauskas
  • Vita Lele
  • Vytaute Starkute
  • Paulina Zavistanaviciute
  • Egle Zokaityte
  • Vadims Bartkevics
  • Dovile Klupsaite
  • Erika Mozuriene
  • Agila Dauksiene
  • Sonata Sidlauskiene
  • Romas Gruzauskas
  • Elena Bartkiene
  • Animals (Basel).2020 Jul;10(7). E1201. doi: 10.3390/ani10071201.Epub 2020-07-15.

レドックス活性なテトラチアフルバレン配位子を用いたコバルト金属-有機フレームワークの開発（第2報）.MOF内のLLCTの構造と光電気化学的特性への影響

Cobalt Metal-Organic Frameworks Incorporating Redox-Active Tetrathiafulvalene Ligand: Structures and Effect of LLCT within the MOF on Photoelectrochemical Properties.
  • Miao Jiang
  • Yi-Gang Weng
  • Zi-Yao Zhou
  • Chen-Yi Ge
  • Qin-Yu Zhu
  • Jie Dai
  • Inorg Chem.2020 Jul;doi: 10.1021/acs.inorgchem.0c01185.Epub 2020-07-18.

ヒトeIF3dとeIF3c、kとlのサブユニットを43Sと48Sのプレイニシエート複合体のアセンブリーに関与していることを示唆しています

Adapted formaldehyde gradient cross-linking protocol implicates human eIF3d and eIF3c, k and l subunits in the 43S and 48S pre-initiation complex assembly, respectively.
  • Anna Herrmannová
  • Terezie Prilepskaja
  • Susan Wagner
  • Darina Šikrová
  • Jakub Zeman
  • Kristýna Poncová
  • Leoš Shivaya Valášek
  • Nucleic Acids Res..2020 02;48(4):1969-1984. 5682903. doi: 10.1093/nar/gkz1185.

ドキソルビシンを用いた肝細胞癌に対するエピルビシンとシスプラチンの経皮注入と5-フルオロウラシルの全身注入の併用療法とソラフェニブの併用療法

Transarterial Infusion of Epirubicin and Cisplatin Combined With Systemic Infusion of 5-Flurouracil Versus Sorafenib for Hepatocellular Carcinoma With Refractoriness of Transarterial Chemoembolization Using Doxorubicin.
  • Sun Hong Yoo
  • Jung Hyun Kwon
  • Soon Woo Nam
  • Jong Yul Lee
  • Young Woon Kim
  • Dong Jae Shim
  • Sung Won Lee
  • Jeong Won Jang
  • Cancer Control.2020 Apr-Jun;27(2):1073274820935843. doi: 10.1177/1073274820935843.

第二世代抗精神病薬の副作用が統合失調症患者の機能に与える影響：世界的な横断的ウェブ調査

The impact on functioning of second-generation antipsychotic medication side effects for patients with schizophrenia: a worldwide, cross-sectional, web-based survey.
  • Rajiv Tandon
  • William R Lenderking
  • Catherine Weiss
  • Huda Shalhoub
  • Carla Dias Barbosa
  • Jun Chen
  • Mallik Greene
  • Stine R Meehan
  • Laëtitia Bouérat Duvold
  • Celso Arango
  • Ofer Agid
  • David Castle
  • Ann Gen Psychiatry.2020;19:42. 292. doi: 10.1186/s12991-020-00292-5.Epub 2020-07-13.

妊娠中の母親のインスリン抵抗性が新生児脂肪率に及ぼす影響の重要性

The importance of maternal insulin resistance throughout pregnancy on neonatal adiposity.
  • Rodrigo A Lima
  • Gernot Desoye
  • David Simmons
  • Roland Devlieger
  • Sander Galjaard
  • Rosa Corcoy
  • Juan M Adelantado
  • Fidelma Dunne
  • Jürgen Harreiter
  • Alexandra Kautzky-Willer
  • Peter Damm
  • Elisabeth R Mathiesen
  • Dorte M Jensen
  • Lise-Lotte T Andersen
  • Mette Tanvig
  • Annunziata Lapolla
  • Maria G Dalfra
  • Alessandra Bertolotto
  • Urszula Manta
  • Ewa Wender-Ozegowska
  • Agnieszka Zawiejska
  • David J Hill
  • Frank J Snoek
  • Judith G M Jelsma
  • Mireille van Poppel
  • Paediatr Perinat Epidemiol.2020 Apr;doi: 10.1111/ppe.12682.Epub 2020-04-30.

トコフェロールの水溶性を高めるための生体適合性超分子ホストとしてのヒアルロン酸ベースのβ-シクロデキストリングラフト共重合体

Hyaluronic-acid-based β-cyclodextrin grafted copolymers as biocompatible supramolecular hosts to enhance the water solubility of tocopherol.
  • Parbeen Singh
  • Li Wu
  • Xiaohong Ren
  • Wei Zhang
  • Yan Tang
  • Yongli Chen
  • Andrew Carrier
  • Xu Zhang
  • Jiwen Zhang
  • Int J Pharm.2020 Jun;586:119542. S0378-5173(20)30526-3. doi: 10.1016/j.ijpharm.2020.119542.Epub 2020-06-14.

バベシアビゲミナに自然感染した牛の酸化ストレス、微量元素、シアル酸、コリンエステラーゼ活性の状態

Status of oxidative stress, trace elements, sialic acid and cholinesterase activity in cattle naturally infected with Babesia bigemina.
  • Bijan Esmaeilnejad
  • Mousa Tavassoli
  • Bahram Dalir-Naghadeh
  • Awat Samiei
  • Sepideh Rajabi
  • Vahid Mohammadi
  • Ehsan Anassori
  • Shahin Ehteshamfar
  • Comp. Immunol. Microbiol. Infect. Dis..2020 May;71:101503. S0147-9571(20)30092-8. doi: 10.1016/j.cimid.2020.101503.Epub 2020-05-30.

PNPLA3-I148M変異体は、ヒト脂肪組織における多価不飽和トリグリセリドを増加させる

The PNPLA3-I148M variant increases polyunsaturated triglycerides in human adipose tissue.
  • Sami Qadri
  • Susanna Lallukka-Brück
  • Panu K Luukkonen
  • You Zhou
  • Amalia Gastaldelli
  • Marju Orho-Melander
  • Henna Sammalkorpi
  • Anne Juuti
  • Anne K Penttilä
  • Julia Perttilä
  • Antti Hakkarainen
  • Tiina E Lehtimäki
  • Matej Orešič
  • Tuulia Hyötyläinen
  • Leanne Hodson
  • Vesa M Olkkonen
  • Hannele Yki-Järvinen
  • Liver Int..2020 May;doi: 10.1111/liv.14507.Epub 2020-05-09.

重度の早期胎児成長制限を有する妊婦における母体のシルデナフィル対プラセボ。無作為化臨床試験

Maternal Sildenafil vs Placebo in Pregnant Women With Severe Early-Onset Fetal Growth Restriction: A Randomized Clinical Trial.
  • Anouk Pels
  • Jan Derks
  • Ayten Elvan-Taspinar
  • Joris van Drongelen
  • Marjon de Boer
  • Hans Duvekot
  • Judith van Laar
  • Jim van Eyck
  • Salwan Al-Nasiry
  • Marieke Sueters
  • Marinka Post
  • Wes Onland
  • Aleid van Wassenaer-Leemhuis
  • Christiana Naaktgeboren
  • Janus C Jakobsen
  • Christian Gluud
  • Ruben G Duijnhoven
  • Titia Lely
  • Sanne Gordijn
  • Wessel Ganzevoort
  • JAMA Netw Open.2020 Jun;3(6):e205323. 2767243. doi: 10.1001/jamanetworkopen.2020.5323.Epub 2020-06-01.

閉塞性睡眠時無呼吸症候群における硬性下顎骨再配置装置と半硬性下顎骨再配置装置の治療機序の違い．

Different therapeutic mechanisms of rigid and semi-rigid mandibular repositioning devices in obstructive sleep apnea syndrome.
  • Hokuto Suga
  • Katsuaki Mishima
  • Hiroyuki Nakano
  • Asuka Nakano
  • Mayumi Matsumura
  • Takamitsu Mano
  • Youichi Yamasaki
  • Yoshiya Ueyama
  • J Craniomaxillofac Surg.2014 Dec;42(8):1650-4. S1010-5182(14)00163-2. doi: 10.1016/j.jcms.2014.05.007.Epub 2014-05-20.

小児における食道pH-インピーダンスモニタリング：SIGENPワーキンググループによる適応、方法、解釈に関するポジションペーパー

Esophageal pH-impedance monitoring in children: position paper on indications, methodology and interpretation by the SIGENP working group.
  • Paolo Quitadamo
  • Renato Tambucci
  • Valentina Mancini
  • Fernanda Cristofori
  • Mariella Baldassarre
  • Licia Pensabene
  • Ruggiero Francavilla
  • Giovanni Di Nardo
  • Tamara Caldaro
  • Paolo Rossi
  • Saverio Mallardo
  • Elena Maggiora
  • Annamaria Staiano
  • Francesco Cresi
  • Silvia Salvatore
  • Osvaldo Borrelli
  • Dig Liver Dis.2019 11;51(11):1522-1536. S1590-8658(19)30718-2. doi: 10.1016/j.dld.2019.07.016.Epub 2019-09-13.

ゼブラフィッシュのマクロファージの発生停止は、ミクログリアの枯渇の下で行われ、Csf1rに依存しない形質転換細胞が明らかになった

Zebrafish macrophage developmental arrest underlies depletion of microglia and reveals Csf1r-independent metaphocytes.
  • Laura E Kuil
  • Nynke Oosterhof
  • Giuliano Ferrero
  • Tereza Mikulášová
  • Martina Hason
  • Jordy Dekker
  • Mireia Rovira
  • Herma C van der Linde
  • Paulina Mh van Strien
  • Emma de Pater
  • Gerben Schaaf
  • Erik Mj Bindels
  • Valerie Wittamer
  • Tjakko J van Ham
  • Elife.2020 May;9. e53403. doi: 10.7554/eLife.53403.Epub 2020-05-05.

急性肝不全における肝移植-10年以上の振り返り

Liver Transplant in Acute Liver Failure - Looking Back Over 10 Years.
  • Shweta Mallick
  • Krishnanunni Nair
  • Manoj Thillai
  • Kathirvel Manikandan
  • Pulkit Sethi
  • Durrairaj Madhusrinivasan
  • Shaji M Johns
  • Sivasankara T Binoj
  • Zubair Mohammed
  • Narayana M Ramachandran
  • Dinesh Balakrishnan
  • Gopalakrishnan Unnikrishnan
  • Puneet Dhar
  • Othiyil V Sudheer
  • Surendran Sudhindran
  • J Clin Exp Hepatol.2020 Jul-Aug;10(4):322-328. S0973-6883(19)30272-5. doi: 10.1016/j.jceh.2019.10.005.Epub 2019-10-31.

KCCM 80179を用いて製造されたl-ヒスチジン一塩酸塩一水和物の全動物種に対する安全性と有効性

Safety and efficacy of l-histidine monohydrochloride monohydrate produced using KCCM 80179 for all animal species.
  • Vasileios Bampidis
  • Giovanna Azimonti
  • Maria de Lourdes Bastos
  • Henrik Christensen
  • Birgit Dusemund
  • Maryline Kouba
  • Mojca Kos Durjava
  • Marta López-Alonso
  • Secundino López Puente
  • Francesca Marcon
  • Baltasar Mayo
  • Alena Pechová
  • Mariana Petkova
  • Yolanda Sanz
  • Roberto Edoardo Villa
  • Ruud Woutersen
  • Lucio Costa
  • Francesco Cubadda
  • Noël Dierick
  • Gerhard Flachowsky
  • Alberto Mantovani
  • Robert John Wallace
  • Paola Manini
  • Jordi Tarrés-Call
  • Fernando Ramos
  • EFSA J.2019 Jul;17(7):e05784. EFS25784. doi: 10.2903/j.efsa.2019.5784.Epub 2019-07-25.

若手バスケットボール選手の意図的な練習、機能的パフォーマンスと心理的特性.ベイズ型マルチレベル分析

Deliberate Practice, Functional Performance and Psychological Characteristics in Young Basketball Players: A Bayesian Multilevel Analysis.
  • Ahlan B Lima
  • Juarez V Nascimento
  • Thiago J Leonardi
  • André L Soares
  • Roberto R Paes
  • Carlos E Gonçalves
  • Humberto M Carvalho
  • Int J Environ Res Public Health.2020 Jun;17(11). E4078. doi: 10.3390/ijerph17114078.Epub 2020-06-08.

P/Q型カルシウムチャネルの新規スプライス部位変異と小児てんかんおよび遅発性進行性非エピソディック小脳運動失調との関連

Association of A Novel Splice Site Mutation in P/Q-Type Calcium Channels with Childhood Epilepsy and Late-Onset Slowly Progressive Non-Episodic Cerebellar Ataxia.
  • Claudia Stendel
  • Maria Cristina D'Adamo
  • Manuela Wiessner
  • Marina Dusl
  • Marta Cenciarini
  • Silvia Belia
  • Ehsan Nematian-Ardestani
  • Peter Bauer
  • Jan Senderek
  • Thomas Klopstock
  • Mauro Pessia
  • Int J Mol Sci.2020 May;21(11). E3810. doi: 10.3390/ijms21113810.Epub 2020-05-27.

緑内障ドレナージ装置設置術およびその他の前房手術後の眼瞼下垂の増加率：プロスペクティブ解析

Increased rate of ptosis following glaucoma drainage device placement and other anterior segment surgery: a prospective analysis.
  • Gavin W Roddy
  • Bingying Zhao
  • Feng Wang
  • Chengbo Fang
  • Sunil S Khanna
  • Jasmina Bajric
  • Cheryl L Khanna
  • Graefes Arch. Clin. Exp. Ophthalmol..2020 Jul;258(7):1533-1541. 10.1007/s00417-020-04630-x. doi: 10.1007/s00417-020-04630-x.Epub 2020-02-26.

インシリコ/インビトロスクリーニングとヒット評価により、新規のフェノチアジン系抗プリオン誘導体が同定された

In silico/in vitro screening and hit evaluation identified new phenothiazine anti-prion derivatives.
  • Ludovica Zaccagnini
  • Giulia Rossetti
  • Thanh Hoa Tran
  • Giulia Salzano
  • Annachiara Gandini
  • Arianna Colini Baldeschi
  • Maria Laura Bolognesi
  • Paolo Carloni
  • Giuseppe Legname
  • Eur J Med Chem.2020 Jun;196:112295. S0223-5234(20)30264-6. doi: 10.1016/j.ejmech.2020.112295.Epub 2020-04-08.

サンパウロ州リベイラオプレト大学病院における糖尿病患者における非糖尿病性腎疾患の有病率

The Prevalence of Nondiabetic Renal Diseases in Patients with Diabetes Mellitus in the University Hospital of Ribeirão Preto, São Paulo.
  • Diego Agra Souza
  • Gyl Eanes Barros Silva
  • Igor Lima Fernandes
  • Dyego José Araújo de Brito
  • Monique Pereira Rêgo Muniz
  • Osvaldo Merege Vieira Neto
  • Roberto Silva Costa
  • Márcio Dantas
  • Miguel Moyses Neto
  • J Diabetes Res.2020;2020:2129459. doi: 10.1155/2020/2129459.Epub 2020-06-13.

高度な酸化生物活性炭プロセスとFe/ヒュームス還元菌を組み合わせた逆浸透濃縮物からの有機物の除去

Removing organic matters from reverse osmosis concentrate using advanced oxidation-biological activated carbon process combined with Fe/humus-reducing bacteria.
  • Xiaoyan Wang
  • Jiaohui Xia
  • Shaoxuan Ding
  • Shuo Zhang
  • Menghong Li
  • Zhenxiao Shang
  • Jie Lu
  • Jincheng Ding
  • Ecotoxicol. Environ. Saf..2020 Jul;203:110945. S0147-6513(20)30784-3. doi: 10.1016/j.ecoenv.2020.110945.Epub 2020-07-15.

新生子豚の母体の鉄の状態と肝鉄貯蔵量にスクロソミアル第二鉄ピロリン酸塩と健康な妊娠中の雌豚の経口サプリメントの効果

Effect of Oral Supplementation of Healthy Pregnant Sows with Sucrosomial Ferric Pyrophosphate on Maternal Iron Status and Hepatic Iron Stores in Newborn Piglets.
  • Rafał Mazgaj
  • Mateusz Szudzik
  • Paweł Lipiński
  • Aneta Jończy
  • Ewa Smuda
  • Marian Kamyczek
  • Beata Cieślak
  • Dorine Swinkels
  • Małgorzata Lenartowicz
  • Rafał R Starzyński
  • Animals (Basel).2020 Jun;10(7). E1113. doi: 10.3390/ani10071113.Epub 2020-06-29.

PCSK9は敗血症性ショック患者の死亡率と関連している：ALBIOS試験のデータ

PCSK9 is associated with mortality in patients with septic shock: data from the ALBIOS study.
  • Alessandra Vecchié
  • Aldo Bonaventura
  • Jennifer Meessen
  • Deborah Novelli
  • Silvia Minetti
  • Edoardo Elia
  • Daniele Ferrara
  • Anna Maria Ansaldo
  • Vittorio Scaravilli
  • Silvia Villa
  • Luca Ferla
  • Pietro Caironi
  • Roberto Latini
  • Federico Carbone
  • Fabrizio Montecucco
  • J. Intern. Med..2020 Jul;doi: 10.1111/joim.13150.Epub 2020-07-19.

大うつ病または双極性障害を有する成人患者における静注ケタミンの安全性と忍容性：カナダのラピッド・トリートメント・センター・オブ・エクセレンスの結果

Safety and tolerability of IV ketamine in adults with major depressive or bipolar disorder: results from the Canadian rapid treatment center of excellence.
  • Nelson B Rodrigues
  • Roger S McIntyre
  • Orly Lipsitz
  • Yena Lee
  • Danielle S Cha
  • Flora Nasri
  • Hartej Gill
  • Leanna M W Lui
  • Mehala Subramaniapillai
  • Kevin Kratiuk
  • Kangguang Lin
  • Roger Ho
  • Rodrigo B Mansur
  • Joshua D Rosenblat
  • Expert Opin Drug Saf.2020 Jun;:1-10. doi: 10.1080/14740338.2020.1776699.Epub 2020-06-15.

結核菌や大腸菌のニコチンアミダーゼ・ピラジナミダーゼ活性にはメタロシャペロンが必要である

Metallochaperones Are Needed for Mycobacterium tuberculosis and Escherichia coli Nicotinamidase-Pyrazinamidase Activity.
  • Patricia Sheen
  • Anuntxi Monsalve
  • Jhanina Campos
  • Rodolfo Huerta
  • Ricardo Antiparra
  • Héctor Arteaga
  • Patricia Duran
  • Carlos Bueno
  • Daniela E Kirwan
  • Robert H Gilman
  • Mirko Zimic
  • J. Bacteriol..2020 Jan;202(2). e00331-19. doi: 10.1128/JB.00331-19.Epub 2020-01-02.

長引く紛争における保健医療従事者の教育・訓練提供の課題：シリア北西部の非政府支配地域に焦点を当てて

Challenges of providing healthcare worker education and training in protracted conflict: a focus on non-government controlled areas in north west Syria.
  • Yamama Bdaiwi
  • Diana Rayes
  • Ammar Sabouni
  • Lina Murad
  • Fouad Fouad
  • Waseem Zakaria
  • Mahmoud Hariri
  • Abdelkarim Ekzayez
  • Ahmad Tarakji
  • Aula Abbara
  • Confl Health.2020;14:42. 287. doi: 10.1186/s13031-020-00287-9.Epub 2020-07-08.

インターロイキン-18と細胞障害は、独立した相乗的な原因であり、マウスウイルス誘発性高炎症の原因である

Interleukin-18 and cytotoxic impairment are independent and synergistic causes of murine virus-induced hyperinflammation.
  • Paul Tsoukas
  • Emily Rapp
  • Lauren Van Der Kraak
  • Eric S Weiss
  • Vinh Dang
  • Corinne Schneider
  • Edwin Klein
  • Jennifer Picarsic
  • Rosalba Salcedo
  • Charles Andrew Stewart
  • Scott Canna
  • Blood.2020 Jun;blood.2019003846. doi: 10.1182/blood.2019003846.Epub 2020-06-26.

vivax マラリア原虫患者におけるタフェノキンの有効性の薬理遺伝学的評価

Pharmacogenetic assessment of tafenoquine efficacy in patients with Plasmodium vivax malaria.
  • Pamela L St Jean
  • Gavin C K W Koh
  • John J Breton
  • Fe E J Espino
  • Tran T Hien
  • Srivicha Krudsood
  • Marcus V G Lacerda
  • Alejandro Llanos-Cuentas
  • Chanthap Lon
  • Rezika Mohammed
  • Chayadol S Namaik-Larp
  • Dhelio B Pereira
  • David L Saunders
  • Ivan D Velez
  • Daniel Yilma
  • Maria F Villegas
  • Stephan Duparc
  • Justin A Green
  • Pharmacogenet. Genomics.2020 Jun;doi: 10.1097/FPC.0000000000000407.Epub 2020-06-16.

カーディオリピンは、細菌のトランスロコンの安定性と最適な膜タンパク質のトランスロケーションと挿入のために、生体内で必要とされています

Cardiolipin is required in vivo for the stability of bacterial translocon and optimal membrane protein translocation and insertion.
  • Sergey Ryabichko
  • Vilena de Melo Ferreira
  • Heidi Vitrac
  • Ramziya Kiyamova
  • William Dowhan
  • Mikhail Bogdanov
  • Sci Rep.2020 Apr;10(1):6296. 10.1038/s41598-020-63280-5. doi: 10.1038/s41598-020-63280-5.Epub 2020-04-14.

西洋のハウスマウスの近東起源とヨーロッパへの飛散を追う

Tracking the Near Eastern origins and European dispersal of the western house mouse.
  • Thomas Cucchi
  • Katerina Papayianni
  • Sophie Cersoy
  • Laetitia Aznar-Cormano
  • Antoine Zazzo
  • Régis Debruyne
  • Rémi Berthon
  • Adrian Bălășescu
  • Alan Simmons
  • François Valla
  • Yannis Hamilakis
  • Fanis Mavridis
  • Marjan Mashkour
  • Jamshid Darvish
  • Roohollah Siahsarvi
  • Fereidoun Biglari
  • Cameron A Petrie
  • Lloyd Weeks
  • Alireza Sardari
  • Sepideh Maziar
  • Christiane Denys
  • David Orton
  • Emma Jenkins
  • Melinda Zeder
  • Jeremy B Searle
  • Greger Larson
  • François Bonhomme
  • Jean-Christophe Auffray
  • Jean-Denis Vigne
  • Sci Rep.2020 May;10(1):8276. 10.1038/s41598-020-64939-9. doi: 10.1038/s41598-020-64939-9.Epub 2020-05-19.

ミスマッチ修復不全癌に対するフレームシフトペプチドネオアンチゲンベースのワクチン。A Phase I/IIa 臨床試験を実施しました

A Frameshift Peptide Neoantigen-Based Vaccine for Mismatch Repair-Deficient Cancers: A Phase I/IIa Clinical Trial.
  • Matthias Kloor
  • Miriam Reuschenbach
  • Claudia Pauligk
  • Julia Karbach
  • Mohammad-Reza Rafiyan
  • Salah-Eddin Al-Batran
  • Mirjam Tariverdian
  • Elke Jäger
  • Magnus von Knebel Doeberitz
  • Clin. Cancer Res..2020 Jun;1078-0432.CCR-19-3517. doi: 10.1158/1078-0432.CCR-19-3517.Epub 2020-06-15.

HER2 陽性乳癌患者 6,122 例を対象とした集団ベースの研究におけるトリプル陽性と予後パラメータおよび全生存期間との関連性：研究データベースに基づく実際の臨床実践の分析

Association of triple positivity with prognostic parameters and overall survival in a population-based study of 6,122 HER2-positive breast cancer patients: analysis of real-world clinical practice based on a research database.
  • I Kolarova
  • J Vanasek
  • M Dolezel
  • J Stuk
  • A Hlavka
  • L Dusek
  • B Melichar
  • T Buchler
  • A Ryska
  • J Prausova
  • K Petrakova
  • P Tesarova
  • J Petera
  • M Vosmik
  • K Horackova
  • J Jarkovsky
  • Neoplasma.2020 Jul;191023N1080. doi: 10.4149/neo_2020_191023N1080.Epub 2020-07-02.

ミトコンドリア障害は、マウスの部分的または完全なジストロフィン喪失の初期の結果である

Mitochondrial Dysfunction Is an Early Consequence of Partial or Complete Dystrophin Loss in Mice.
  • Timothy M Moore
  • Amanda J Lin
  • Alexander R Strumwasser
  • Kevin Cory
  • Kate Whitney
  • Theodore Ho
  • Timothy Ho
  • Joseph L Lee
  • Daniel H Rucker
  • Christina Q Nguyen
  • Aidan Yackly
  • Sushil K Mahata
  • Jonathan Wanagat
  • Linsey Stiles
  • Lorraine P Turcotte
  • Rachelle H Crosbie
  • Zhenqi Zhou
  • Front Physiol.2020;11:690. doi: 10.3389/fphys.2020.00690.Epub 2020-06-19.

東・南部アフリカにおける性と生殖のための健康商品へのアクセス：ケニア、タンザニア、ウガンダ、ザンビアにおける入手可能性、手頃な価格、在庫切れについてのクロスカントリー比較

Access to sexual and reproductive health commodities in East and Southern Africa: a cross-country comparison of availability, affordability and stock-outs in Kenya, Tanzania, Uganda and Zambia.
  • Gaby I Ooms
  • Denis Kibira
  • Tim Reed
  • Hendrika A van den Ham
  • Aukje K Mantel-Teeuwisse
  • Gemma Buckland-Merrett
  • BMC Public Health.2020 Jul;20(1):1053. 10.1186/s12889-020-09155-w. doi: 10.1186/s12889-020-09155-w.Epub 2020-07-03.

ヨーロッパにおけるヒトおよびイヌの常在菌感染症。イタリアの10代におけるヒトの症例報告と文献の系統的レビュー

Autochthonous Human and Canine Infection in Europe: Report of a Human Case in An Italian Teen and Systematic Review of the Literature.
  • Letizia Ottino
  • Dora Buonfrate
  • Paola Paradies
  • Zeno Bisoffi
  • Alberto Antonelli
  • Gian Maria Rossolini
  • Simona Gabrielli
  • Alessandro Bartoloni
  • Lorenzo Zammarchi
  • Pathogens.2020 Jun;9(6). E439. doi: 10.3390/pathogens9060439.Epub 2020-06-03.

COVID-19パンデミック時の急性重篤な資源制約の中での頭頸部外科腫瘍学の実践のための推奨事項：国際的なコンセンサス

Recommendations for head and neck surgical oncology practice in a setting of acute severe resource constraint during the COVID-19 pandemic: an international consensus.
  • Hisham Mehanna
  • John C Hardman
  • Jared A Shenson
  • Ahmad K Abou-Foul
  • Michael C Topf
  • Mohammad AlFalasi
  • Jason Y K Chan
  • Pankaj Chaturvedi
  • Velda Ling Yu Chow
  • Andreas Dietz
  • Johannes J Fagan
  • Christian Godballe
  • Wojciech Golusiński
  • Akihiro Homma
  • Sefik Hosal
  • N Gopalakrishna Iyer
  • Cyrus Kerawala
  • Yoon Woo Koh
  • Anna Konney
  • Luiz P Kowalski
  • Dennis Kraus
  • Moni A Kuriakose
  • Efthymios Kyrodimos
  • Stephen Y Lai
  • C Rene Leemans
  • Paul Lennon
  • Lisa Licitra
  • Pei-Jen Lou
  • Bernard Lyons
  • Haitham Mirghani
  • Anthonny C Nichols
  • Vinidh Paleri
  • Benedict J Panizza
  • Pablo Parente Arias
  • Mihir R Patel
  • Cesare Piazza
  • Danny Rischin
  • Alvaro Sanabria
  • Robert P Takes
  • David J Thomson
  • Ravindra Uppaluri
  • Yu Wang
  • Sue S Yom
  • Yi-Ming Zhu
  • Sandro V Porceddu
  • John R de Almeida
  • Chrisian Simon
  • F Christopher Holsinger
  • Lancet Oncol..2020 07;21(7):e350-e359. S1470-2045(20)30334-X. doi: 10.1016/S1470-2045(20)30334-X.Epub 2020-06-11.

Aphis glycines virus 1は、2つの機能的な内部リボソームエントリーサイトを持つ新しいビシストロン型ウイルスであるが、この種の未分類ウイルスのグループに関連している

Aphis glycines virus 1, a new bicistronic virus with two functional internal ribosome entry sites, is related to a group of unclassified viruses in the .
  • Tuba Yasmin
  • Thanuja Thekke-Veetil
  • Houston A Hobbs
  • Berlin D Nelson
  • Nancy K McCoppin
  • Doris Lagos-Kutz
  • Glen L Hartman
  • Kris N Lambert
  • David R Walker
  • Leslie L Domier
  • J. Gen. Virol..2020 Jan;101(1):105-111. doi: 10.1099/jgv.0.001355.

形態学的特徴、運動学的特徴、および時空間的特徴の選択を組み合わせたマルチパラメトリックモデルを用いた、塊状病変のダイナミックコントラスト強調乳房MRIのためのコンピュータ支援診断

Computer-aided diagnosis for dynamic contrast-enhanced breast MRI of mass-like lesions using a multiparametric model combining a selection of morphological, kinetic, and spatiotemporal features.
  • S Agliozzo
  • M De Luca
  • C Bracco
  • A Vignati
  • V Giannini
  • L Martincich
  • L A Carbonaro
  • A Bert
  • F Sardanelli
  • D Regge
  • Med Phys.2012 Apr;39(4):1704-15. doi: 10.1118/1.3691178.

ヒト細胞におけるH9N2インフルエンザウイルスの感染には、NAシアルダーゼ活性とHA受容体親和性のバランスが必要であることが明らかになった

H9N2 influenza virus infections in human cells require a balance between NA sialidase activity and HA receptor affinity.
  • Yasuha Arai
  • Emad Mohamed Elgendy
  • Tomo Daidoji
  • Madiha Salah Ibrahim
  • Takao Ono
  • Nongluk Sriwilaijaroen
  • Yasuo Suzuki
  • Takaaki Nakaya
  • Kazuhiko Matsumoto
  • Yohei Watanabe
  • J. Virol..2020 Jul;JVI.01210-20. doi: 10.1128/JVI.01210-20.Epub 2020-07-08.

ポリメチレングリーンを炭素表面にグラフトしたフラビンアデニンジヌクレオチド依存性グルコースデヒドロゲナーゼを触媒とするグルコースの電気化学的酸化を媒介とした研究を行った

Mediated electrochemical oxidation of glucose via poly(methylene green) grafted on the carbon surface catalyzed by flavin adenine dinucleotide-dependent glucose dehydrogenase.
  • Nozomu Tsuruoka
  • Silvia Sato Soto
  • Awatef Ben Tahar
  • Abdelkader Zebda
  • Seiya Tsujimura
  • Colloids Surf B Biointerfaces.2020 Apr;192:111065. S0927-7765(20)30295-2. doi: 10.1016/j.colsurfb.2020.111065.Epub 2020-04-21.

内皮機能障害における酸化ストレスと新たな病態メカニズム.潜在的な診断バイオマーカーと治療ターゲット

Oxidative Stress and New Pathogenetic Mechanisms in Endothelial Dysfunction: Potential Diagnostic Biomarkers and Therapeutic Targets.
  • Maria Giovanna Scioli
  • Gabriele Storti
  • Federico D'Amico
  • Roger Rodríguez Guzmán
  • Federica Centofanti
  • Elena Doldo
  • Ela María Céspedes Miranda
  • Augusto Orlandi
  • J Clin Med.2020 Jun;9(6). E1995. doi: 10.3390/jcm9061995.Epub 2020-06-25.

フランスの古代ゲノムワイドDNAは、中石器時代の狩猟採集民と新石器時代の農民との間の相互作用の複雑さを浮き彫りにした

Ancient genome-wide DNA from France highlights the complexity of interactions between Mesolithic hunter-gatherers and Neolithic farmers.
  • Maïté Rivollat
  • Choongwon Jeong
  • Stephan Schiffels
  • İşil Küçükkalıpçı
  • Marie-Hélène Pemonge
  • Adam Benjamin Rohrlach
  • Kurt W Alt
  • Didier Binder
  • Susanne Friederich
  • Emmanuel Ghesquière
  • Detlef Gronenborn
  • Luc Laporte
  • Philippe Lefranc
  • Harald Meller
  • Hélène Réveillas
  • Eva Rosenstock
  • Stéphane Rottier
  • Chris Scarre
  • Ludovic Soler
  • Joachim Wahl
  • Johannes Krause
  • Marie-France Deguilloux
  • Wolfgang Haak
  • Sci Adv.2020 May;6(22):eaaz5344. aaz5344. doi: 10.1126/sciadv.aaz5344.Epub 2020-05-29.

COVID-19パンデミック時の重要重要インフラストラクチャー職種の労働者における健康関連職場欠勤の増加-米国、2020年3月～4月

Increases in Health-Related Workplace Absenteeism Among Workers in Essential Critical Infrastructure Occupations During the COVID-19 Pandemic - United States, March-April 2020.
  • Matthew R Groenewold
  • Sherry L Burrer
  • Faruque Ahmed
  • Amra Uzicanin
  • Hannah Free
  • Sara E Luckhaupt
  • MMWR Morb. Mortal. Wkly. Rep..2020 Jul;69(27):853-858. doi: 10.15585/mmwr.mm6927a1.Epub 2020-07-10.

新石器時代のピットウェア文化の狩猟者は、文化的な影響を受けていたが、バトルアックス文化の狩猟者には遺伝的な影響を受けていなかった

The Neolithic Pitted Ware culture foragers were culturally but not genetically influenced by the Battle Axe culture herders.
  • Alexandra Coutinho
  • Torsten Günther
  • Arielle R Munters
  • Emma M Svensson
  • Anders Götherström
  • Jan Storå
  • Helena Malmström
  • Mattias Jakobsson
  • Am. J. Phys. Anthropol..2020 Jun;doi: 10.1002/ajpa.24079.Epub 2020-06-04.

アボカド種子抽出物の化学組成、毒性および幼虫殺虫・抗真菌活性（英文

Chemical composition, toxicity and larvicidal and antifungal activities of Persea americana (avocado) seed extracts.
  • João Jaime Giffoni Leite
  • Erika Helena Salles Brito
  • Rossana Aguiar Cordeiro
  • Raimunda Sâmia Nogueira Brilhante
  • José Júlio Costa Sidrim
  • Luciana Medeiros Bertini
  • Selene Maia de Morais
  • Marcos Fábio Gadelha Rocha
  • Rev. Soc. Bras. Med. Trop..2009 Mar-Apr;42(2):110-3. S0037-86822009000200003. doi: 10.1590/s0037-86822009000200003.

モルヒネは、ヒトのミューオピオイド受容体スプライス変異体を発現するヒト化マウスにおいて、強力な抗侵害症状、鎮静、および低体温を産生する

Morphine produces potent antinociception, sedation, and hypothermia in humanized mice expressing human mu-opioid receptor splice variants.
  • Yi-Han Huang
  • Yu-Wei Wu
  • Jian-Ying Chuang
  • Yung-Chiao Chang
  • Hsiao-Fu Chang
  • Pao-Luh Tao
  • Horace H Loh
  • Shiu-Hwa Yeh
  • Pain.2020 06;161(6):1177-1190. doi: 10.1097/j.pain.0000000000001823.

また、このように、細胞内でのリソゾームの修復、除去、置換を調整する細胞システムであるMERITは、リソゾームの修復、除去、置換を調整する細胞システムである

MERIT, a cellular system coordinating lysosomal repair, removal and replacement.
  • Jingyue Jia
  • Aurore Claude-Taupin
  • Yuexi Gu
  • Seong Won Choi
  • Ryan Peters
  • Bhawana Bissa
  • Michal H Mudd
  • Lee Allers
  • Sandeep Pallikkuth
  • Keith A Lidke
  • Michelle Salemi
  • Brett Phinney
  • Muriel Mari
  • Fulvio Reggiori
  • Vojo Deretic
  • Autophagy.2020 Jun;:1-3. doi: 10.1080/15548627.2020.1779451.Epub 2020-06-21.

Xanthomonas oryzae pv. oryzae由来のマイナーエフェクトウイルス性因子を用いたスクリーニングにより、イネMAGIC集団における抵抗性と感受性のQTLを同定した

Resistance and susceptibility QTL identified in a rice MAGIC population by screening with a minor-effect virulence factor from Xanthomonas oryzae pv. oryzae.
  • Alejandra I Huerta
  • Emily E Delorean
  • Ana M Bossa-Castro
  • Bradley W Tonnessen
  • Chitra Raghavan
  • Rene Corral
  • Álvaro L Pérez-Quintero
  • Hei Leung
  • Valérie Verdier
  • Jan E Leach
  • Plant Biotechnol. J..2020 Jun;doi: 10.1111/pbi.13438.Epub 2020-06-28.

持続性カテコラミン抵抗性ショックの小児における全身血管抵抗性指数と血清乳酸値の死亡予測力の比較

Comparison of Predictive Powers for Mortality between Systemic Vascular Resistance Index and Serum Lactate in Children with Persistent Catecholamine-Resistant Shock.
  • En-Pei Lee
  • Sheng-Chih Chu
  • Shao-Hsuan Hsia
  • Kuan-Fu Chen
  • Oi-Wa Chan
  • Chia-Ying Lin
  • Ya-Ting Su
  • Jainn-Jim Lin
  • Han-Ping Wu
  • Biomed Res Int.2020;2020:1341326. doi: 10.1155/2020/1341326.Epub 2020-06-19.

プラチナ抵抗性子宮頸がんに対するアクサリモジン・フィロリスバック（ADXS-HPV）の第II相試験：NRG腫瘍学/婦人科腫瘍学グループ試験

Phase II study of axalimogene filolisbac (ADXS-HPV) for platinum-refractory cervical carcinoma: An NRG oncology/gynecologic oncology group study.
  • Warner K Huh
  • William E Brady
  • Paula M Fracasso
  • Don S Dizon
  • Matthew A Powell
  • Bradley J Monk
  • Charles A Leath
  • Lisa M Landrum
  • Edward J Tanner
  • Erin K Crane
  • Stefanie Ueda
  • Michael T McHale
  • Carol Aghajanian
  • Gynecol. Oncol..2020 Jul;S0090-8258(20)32317-9. doi: 10.1016/j.ygyno.2020.06.493.Epub 2020-07-05.

ラットモデルを用いた90分持続重度出血性ショック（血液量2/3喪失）の蘇生療法において、心毒性のない新規ナノバイオ治療薬ポリヘモグロビン-スーパーオキシドジスムターゼ-カタラーゼ-カルボン酸無水物酵素を開発した

A novel nanobiotherapeutic poly-[hemoglobin-superoxide dismutase-catalase-carbonic anhydrase] with no cardiac toxicity for the resuscitation of a rat model with 90 minutes of sustained severe hemorrhagic shock with loss of 2/3 blood volume.
  • Yuzhu Bian
  • Thomas Ming Swi Chang
  • Artif Cells Nanomed Biotechnol.2015 Feb;43(1):1-9. doi: 10.3109/21691401.2014.964554.Epub 2014-10-09.

エチオピアのアファール州ミルロギアの化石は、鮮新世の環境変化とホモの起源との関連を明らかにした

Fossils from Mille-Logya, Afar, Ethiopia, elucidate the link between Pliocene environmental changes and Homo origins.
  • Zeresenay Alemseged
  • Jonathan G Wynn
  • Denis Geraads
  • Denne Reed
  • W Andrew Barr
  • René Bobe
  • Shannon P McPherron
  • Alan Deino
  • Mulugeta Alene
  • Mark J Sier
  • Diana Roman
  • Joseph Mohan
  • Nat Commun.2020 May;11(1):2480. 10.1038/s41467-020-16060-8. doi: 10.1038/s41467-020-16060-8.Epub 2020-05-19.

3'翻訳されていない領域の短い直接リピートは、サブゲノムのフラビウイルスRNA産生に関与している

Short Direct Repeats in the 3' Untranslated Region Are Involved in Subgenomic Flaviviral RNA Production.
  • Qiu-Yan Zhang
  • Xiao-Feng Li
  • Xiaolin Niu
  • Na Li
  • Hong-Jiang Wang
  • Cheng-Lin Deng
  • Han-Qing Ye
  • Xing-Yao Huang
  • Qi Chen
  • Yan-Peng Xu
  • Hao-Long Dong
  • Xiao-Dan Li
  • Hui Zhao
  • Pei-Yong Shi
  • Zhi-Ming Yuan
  • Peng Gong
  • Xianyang Fang
  • Cheng-Feng Qin
  • Bo Zhang
  • J. Virol..2020 Feb;94(6). e01175-19. doi: 10.1128/JVI.01175-19.Epub 2020-02-28.

ペニシリン結合タンパク質4の結合を介した銀ナノ粒子の合成、インビトロおよびインシリコ評価（英文

Synthesis, in-vitro and in-silico evaluation of Silver Nanoparticles with Root Extract of Withania somnifera for antibacterial activity via binding of penicillin binding protein-4.
  • Isha Gaurav
  • Tanuja Singh
  • Abhimanyu Thakur
  • Gaurav Kumar
  • Parth Rathee
  • Puja Kumari
  • Kumari Sweta
  • Curr Pharm Biotechnol.2020 Jul;CPB-EPUB-107862. doi: 10.2174/1389201021666200702152000.Epub 2020-07-02.

中国・張光閣嶺西斜面の二次林における異なる生息地に生育したユグリカの苗木の根構造と細根特性

[Root architecture and fine root characteristics of Juglans mandshurica saplings in different habitats in the secondary forest on the west slope of Zhangguangcailing, China].
  • Li-Qing Xu
  • Dong-Hai Cui
  • Qing-Cheng Wang
  • Yong Zhang
  • Shuang-Jiao Ma
  • Kai-Yue Zhu
  • Jian-Wen Hu
  • Hong-Li Li
  • Ying Yong Sheng Tai Xue Bao.2020 Feb;31(2):373-380. doi: 10.13287/j.1001-9332.202002.009.

マウス筋ジストロフィーモデルにおける高い治療ポテンシャルを持つヒト胎児筋幹細胞の誘導

Induced Fetal Human Muscle Stem Cells with High Therapeutic Potential in a Mouse Muscular Dystrophy Model.
  • Mingming Zhao
  • Atsutoshi Tazumi
  • Satoru Takayama
  • Nana Takenaka-Ninagawa
  • Minas Nalbandian
  • Miki Nagai
  • Yumi Nakamura
  • Masanori Nakasa
  • Akira Watanabe
  • Makoto Ikeya
  • Akitsu Hotta
  • Yuta Ito
  • Takahiko Sato
  • Hidetoshi Sakurai
  • Stem Cell Reports.2020 Jul;15(1):80-94. S2213-6711(20)30225-3. doi: 10.1016/j.stemcr.2020.06.004.Epub 2020-07-02.

Nootkatone はマウスの急性および慢性炎症反応を抑制します

Nootkatone Inhibits Acute and Chronic Inflammatory Responses in Mice.
  • Lindaiane Bezerra Rodrigues Dantas
  • Ana Letícia Moreira Silva
  • Cícero Pedro da Silva Júnior
  • Isabel Sousa Alcântara
  • Maria Rayane Correia de Oliveira
  • Anita Oliveira Brito Pereira Bezerra Martins
  • Jaime Ribeiro-Filho
  • Henrique Douglas Melo Coutinho
  • Fabíolla Rocha Santos Passos
  • Lucindo José Quintans-Junior
  • Irwin Rose Alencar de Menezes
  • Raffaele Pezzani
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  • Molecules.2020 May;25(9). E2181. doi: 10.3390/molecules25092181.Epub 2020-05-07.

ゲノムワイドなCRISPRスクリーニングにより、胆嚢癌におけるゲムシタビン感受性の決定因子としてELP5が同定された

Genome-wide CRISPR screen identifies ELP5 as a determinant of gemcitabine sensitivity in gallbladder cancer.
  • Sunwang Xu
  • Ming Zhan
  • Cen Jiang
  • Min He
  • Linhua Yang
  • Hui Shen
  • Shuai Huang
  • Xince Huang
  • Ruirong Lin
  • Yongheng Shi
  • Qiang Liu
  • Wei Chen
  • Man Mohan
  • Jian Wang
  • Nat Commun.2019 12;10(1):5492. 10.1038/s41467-019-13420-x. doi: 10.1038/s41467-019-13420-x.Epub 2019-12-02.

生殖補助技術で行われているような単一の卵巣刺激は、ラットのストレス関連脳領域における不安様行動と神経細胞の活性化を調節することができます

A single ovarian stimulation, as performed in assisted reproductive technologies, can modulate the anxiety-like behavior and neuronal activation in stress-related brain areas in rats.
  • Flora França Nogueira Mariotti
  • Bianca Santos Martins Gonçalves
  • Giovanna Pimpão
  • Marcos Mônico-Neto
  • Hanna Karen Moreira Antunes
  • Milena de Barros Viana
  • Isabel Cristina Céspedes
  • Luciana Le Sueur-Maluf
  • Horm Behav.2020 Jun;124:104805. S0018-506X(20)30131-8. doi: 10.1016/j.yhbeh.2020.104805.Epub 2020-06-20.

大脳基底ガングリアとポンティーヌ脳卒中のデフォルトモードネットワークとセンサー運動ネットワーク内の機能的な接続性変化の異なるパターン

Different Patterns of Functional Connectivity Alterations Within the Default-Mode Network and Sensorimotor Network in Basal Ganglia and Pontine Stroke.
  • Huiyou Chen
  • Mengye Shi
  • Hong Zhang
  • Ying-Dong Zhang
  • Wen Geng
  • Liang Jiang
  • Zhengqian Wang
  • Yu-Chen Chen
  • Xindao Yin
  • Med. Sci. Monit..2019 Dec;25:9585-9593. 918185. doi: 10.12659/MSM.918185.Epub 2019-12-15.

救急部の細菌性患者における抗生物質投与遅延の予測因子：内科研修医と外科研修医の違い

Predictors for delayed antibiotic administration among bacteraemic patients in the Emergency Department: differences between medical and surgical interns.
  • Matthaios Papadimitriou-Olivgeris
  • Konstantinos Perdikis
  • Michela Cois
  • Léa Roth
  • Sofia Mykoniati
  • Charly Nusbaumer
  • Luce Bertaiola Monnerat
  • Hervé Duplain
  • Eur. J. Clin. Invest..2020 Jun;:e13324. doi: 10.1111/eci.13324.Epub 2020-06-21.

ヤギの重要臓器におけるCorynebacterium pseudotuberculosisとその免疫原性ミコール酸抽出物の臨床病理学的反応とPCR検出

Clinico-pathological responses and PCR detection of Corynebacterium pseudotuberculosis and its immunogenic mycolic acid extract in the vital organs of goats.
  • Mohammed Naji Odhah
  • Faez Firdaus Abdullah Jesse
  • Eric Lim Teik Chung
  • Zaid Mahmood
  • Abd Wahid Haron
  • Mohd Azmi Mohd Lila
  • Mohd Zamri-Saad
  • Microb. Pathog..2019 Oct;135:103628. S0882-4010(19)30985-4. doi: 10.1016/j.micpath.2019.103628.Epub 2019-07-17.

シトルルス・アマルスのFusarium oxysporum f. sp. niveum race 2とパパイヤリングスポットウイルスに対する抵抗性のQTLマッピング

QTL mapping of resistance to Fusarium oxysporum f. sp. niveum race 2 and Papaya ringspot virus in Citrullus amarus.
  • Sandra E Branham
  • W Patrick Wechter
  • Kai-Shu Ling
  • Bidisha Chanda
  • Laura Massey
  • Guangwei Zhao
  • Nihat Guner
  • Marco Bello
  • Eileen Kabelka
  • Zhangjun Fei
  • Amnon Levi
  • Theor. Appl. Genet..2020 Feb;133(2):677-687. 10.1007/s00122-019-03500-3. doi: 10.1007/s00122-019-03500-3.Epub 2019-12-10.

ウイルス性心筋炎は、CVB3感染モデルのマウスにおいて、リンパ系および非リンパ系臓器に局在する複数の抗原特異性を有する自己反応性T細胞の発生を伴う

Viral myocarditis involves the generation of autoreactive T cells with multiple antigen specificities that localize in lymphoid and non-lymphoid organs in the mouse model of CVB3 infection.
  • Rakesh H Basavalingappa
  • Rajkumar Arumugam
  • Ninaad Lasrado
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  • Chandirasegaran Massilamany
  • Arunakumar Gangaplara
  • Jean-Jack Riethoven
  • Shi-Hua Xiang
  • David Steffen
  • Jay Reddy
  • Mol. Immunol..2020 Aug;124:218-228. S0161-5890(20)30395-3. doi: 10.1016/j.molimm.2020.06.017.Epub 2020-06-29.

分類できない特発性間質性肺炎の急性増悪：特発性肺線維症との比較．

Acute exacerbation of unclassifiable idiopathic interstitial pneumonia: comparison with idiopathic pulmonary fibrosis.
  • Noriyuki Enomoto
  • Hyogo Naoi
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  • Mineo Katsumata
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  • Naoki Inui
  • Yutaro Nakamura
  • Takafumi Suda
  • Ther Adv Respir Dis.2020 Jan-Dec;14:1753466620935774. doi: 10.1177/1753466620935774.

地球の熱帯林の長期的な熱感度

Long-term thermal sensitivity of Earth's tropical forests.
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  • Plínio Barbosa Camargo
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  • Sarah A Batterman
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  • Erika Berenguer
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心理社会的および健康関連の介入の実施構成と結果を評価するためのドイツ語の質問票：システマティックレビュー

German language questionnaires for assessing implementation constructs and outcomes of psychosocial and health-related interventions: a systematic review.
  • Christina Kien
  • Marie-Therese Schultes
  • Monika Szelag
  • Rudolf Schoberberger
  • Gerald Gartlehner
  • Implement Sci.2018 12;13(1):150. 10.1186/s13012-018-0837-3. doi: 10.1186/s13012-018-0837-3.Epub 2018-12-12.

新規フェノチアジン架橋ポルフィリン-(ヘテロ)アリールダイアド。合成、光学特性、体外細胞毒性、ヒト卵巣腫瘍細胞株の染色

Novel Phenothiazine-Bridged Porphyrin-(Hetero)aryl dyads: Synthesis, Optical Properties, In Vitro Cytotoxicity and Staining of Human Ovarian Tumor Cell Lines.
  • Eva Molnar
  • Emese Gal
  • Luiza Gaina
  • Castelia Cristea
  • Eva Fischer-Fodor
  • Maria Perde-Schrepler
  • Patriciu Achimas-Cadariu
  • Monica Focsan
  • Luminita Silaghi-Dumitrescu
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