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日本語AIでPubMedを検索

歯科医師情報サイトTOP / PubMed論文検索

日本語AIでPubMedを検索

PubMedの提供する医学論文データベースを日本語で検索できます。AI(Deep Learning)を活用した機械翻訳エンジンにより、精度高く日本語へ翻訳された論文をご参照いただけます。
対象期間    ～ 

2020年07月 みんなが読んでいる論文

血液由来樹状細胞ワクチン接種は、化学療法を受けていない去勢抵抗性前立腺癌患者の臨床転帰と相関する免疫応答を誘導する

Blood-derived dendritic cell vaccinations induce immune responses that correlate with clinical outcome in patients with chemo-naive castration-resistant prostate cancer.
  • Harm Westdorp
  • Jeroen H A Creemers
  • Inge M van Oort
  • Gerty Schreibelt
  • Mark A J Gorris
  • Niven Mehra
  • Michiel Simons
  • Anna L de Goede
  • Michelle M van Rossum
  • Alexandra J Croockewit
  • Carl G Figdor
  • J Alfred Witjes
  • Erik H J G Aarntzen
  • Roel D M Mus
  • Mareke Brüning
  • Katja Petry
  • Martin Gotthardt
  • Jelle O Barentsz
  • I Jolanda M de Vries
  • Winald R Gerritsen
  • J Immunother Cancer.2019 11;7(1):302. 10.1186/s40425-019-0787-6. doi: 10.1186/s40425-019-0787-6.Epub 2019-11-14.

妊娠におけるリンパ球の機能的意義と不妊治療におけるリンパ球免疫療法。包括的なレビューとアップデート

Functional significance of lymphocytes in pregnancy and lymphocyte immunotherapy in infertility: A comprehensive review and update.
  • Roghayeh Jafarpour
  • Salar Pashangzadeh
  • Saber Mehdizadeh
  • Hashem Bayatipoor
  • Zeinab Shojaei
  • Morteza Motallebnezhad
  • Int. Immunopharmacol..2020 Jul;87:106776. S1567-5769(20)31601-5. doi: 10.1016/j.intimp.2020.106776.Epub 2020-07-15.

MEESSI-AHFリスクスコアの性能によるインデックス後の複数のイベントと退院後の短期転帰の予測

MEESSI-AHF risk score performance to predict multiple post-index event and post-discharge short-term outcomes.
  • Xavier Rossello
  • Héctor Bueno
  • Víctor Gil
  • Javier Jacob
  • Francisco Javier Martín-Sánchez
  • Pere Llorens
  • Pablo Herrero Puente
  • Aitor Alquézar-Arbé
  • Sergio Raposeiras-Roubín
  • M Pilar López-Díez
  • Stuart Pocock
  • Òscar Miró
  • Eur Heart J Acute Cardiovasc Care.2020 Jul;:2048872620934318. doi: 10.1177/2048872620934318.Epub 2020-07-17.

転移性乳癌患者における循環腫瘍細胞のアンドロゲン受容体の状態の決定

Determination of the androgen receptor status of circulating tumour cells in metastatic breast cancer patients.
  • Natalia Krawczyk
  • Melissa Neubacher
  • Franziska Meier-Stiegen
  • Hans Neubauer
  • Dieter Niederacher
  • Eugen Ruckhäberle
  • Svjetlana Mohrmann
  • Jürgen Hoffmann
  • Thomas Kaleta
  • Malgorzata Banys-Paluchowski
  • Petra Reinecke
  • Irene Esposito
  • Wolfgang Janni
  • Tanja Fehm
  • BMC Cancer.2019 Nov;19(1):1101. 10.1186/s12885-019-6323-8. doi: 10.1186/s12885-019-6323-8.Epub 2019-11-12.

脳血管急性障害で母体が死亡した場合の周産期転帰：日本における全国調査

Perinatal outcome in case of maternal death for cerebrovascular acute disorders: a nationwide study in Japan.
  • Shinji Katsuragi
  • Hiroaki Tanaka
  • Junichi Hasegawa
  • Akiko Kurasaki
  • Masamitsu Nakamura
  • Naohiro Kanayama
  • Masahiko Nakata
  • Eijiro Hayata
  • Takeshi Murakoshi
  • Jun Yoshimatsu
  • Kazuhiro Osato
  • Kayo Tanaka
  • Tomoaki Oda
  • Akihiko Sekizawa
  • Takako Shimaoka
  • Isamu Ishiwata
  • Jun Takahashi
  • Tomoaki Ikeda
  • J. Matern. Fetal. Neonatal. Med..2020 Jul;:1-6. doi: 10.1080/14767058.2020.1786511.Epub 2020-07-16.

消化管平滑筋腫瘍：407例における予後の特徴の解析

Smooth muscle tumors of the gastrointestinal tract: an analysis of prognostic features in 407 cases.
  • Lindsay Alpert
  • Ram Al-Sabti
  • Rondell P Graham
  • Rish K Pai
  • Raul S Gonzalez
  • Xuefeng Zhang
  • Vanessa Smith
  • Hanlin L Wang
  • Lindsey Westbrook
  • John R Goldblum
  • Ahmed Bakhshwin
  • Sindhu Shetty
  • David S Klimstra
  • Jinru Shia
  • Gokce Askan
  • Marie E Robert
  • Courtney Thomas
  • Wendy L Frankel
  • Mohammed Alsomali
  • Catherine Hagen
  • Mohamed E Mostafa
  • Michael M Feely
  • Naziheh Assarzadegan
  • Joseph Misdraji
  • Angela R Shih
  • Diana Agostini-Vulaj
  • Jeanne M Meis
  • Sherry Tang
  • Deyali Chatterjee
  • Liang-I Kang
  • John Hart
  • Sang Mee Lee
  • Theresa Smith
  • Rhonda K Yantiss
  • Erika M Hissong
  • Zu-Hua Gao
  • JingBo Wu
  • Murray B Resnick
  • Elizabeth Yiru Wu
  • Reet K Pai
  • Lei Zhao
  • Leona A Doyle
  • Shefali Chopra
  • Nicole C Panarelli
  • Shaomin Hu
  • Teri A Longacre
  • Shyam Sampath Raghavan
  • Gregory Y Lauwers
  • Masoumeh Ghayouri
  • Harry S Cooper
  • Rajeswari Nagarathinam
  • Andrew M Bellizzi
  • Sanjay Kakar
  • Mojgan Hosseini
  • Juan Rong
  • Joel K Greenson
  • Laura W Lamps
  • Zachary Dong
  • Mary P Bronner
  • Mod. Pathol..2020 Jul;33(7):1410-1419. 10.1038/s41379-020-0492-5. doi: 10.1038/s41379-020-0492-5.Epub 2020-02-12.

脊髄軟骨腫のヘリカルトモセラピー。30例のコホートを対象としたフランスの多中心的、レトロスペクティブ研究

Helical tomotherapy of spinal chordomas: French Multicentric, retrospective study of a cohort of 30 cases.
  • Maxime Bobin
  • Christina Zacharatou
  • Paul Sargos
  • Véronique Brouste
  • Albert Lisbona
  • Marc-André Mahé
  • Georges Noël
  • Amandine Halley
  • Loïc Feuvret
  • Louis Gras
  • Stéphanie Hoppe
  • Bénédicte Henriques de Figueiredo
  • Guy Kantor
  • Radiat Oncol.2017 Jan;12(1):32. 10.1186/s13014-017-0768-1. doi: 10.1186/s13014-017-0768-1.Epub 2017-01-31.

高齢者の非特異的腰痛に対する保存的治療の有効性。メタアナリシスとGRADE推奨のシステマティックレビュー

Efficacy of conservative therapy in older people with nonspecific low back pain: A systematic review with meta-analysis and GRADE recommendations.
  • Lorena K B Amaral
  • Mateus B Souza
  • Mariana G M Campos
  • Vanessa A Mendonça
  • Alessandra Bastone
  • Leani S M Pereira
  • Rodrigo O Mascarenhas
  • Vinicius C Oliveira
  • Arch Gerontol Geriatr.2020 Jul;90:104177. S0167-4943(20)30171-0. doi: 10.1016/j.archger.2020.104177.Epub 2020-07-11.

中国福山油田の土壌中の石油系炭化水素汚染を迅速に判定・評価するための加速溶媒抽出法とガスクロマトグラフィー-火炎イオン化検出器法を開発した

An accelerated solvent extraction and gas chromatography-flame ionization detector method to rapidly determining and assessing total petroleum hydrocarbon contamination in soil from Fushan oilfield, China.
  • Tengya Li
  • Xiaocong Cao
  • Shuhai He
  • Mingshan Zhang
  • Wenshuai Xu
  • Zengheng Xiong
  • Yan Liang
  • Chenye Wang
  • Biaojuan Chen
  • Environ Sci Pollut Res Int.2020 Jul;10.1007/s11356-020-09418-4. doi: 10.1007/s11356-020-09418-4.Epub 2020-07-18.

小児介在性循環器科カテーテル検査の代表的な値。診断基準値の確立に向けた標準化されたアプローチ

Typical values for pediatric interventional cardiology catheterizations: A standardized approach towards Diagnostic Reference Level establishment.
  • Francesca De Monte
  • Biagio Castaldi
  • Marco Branchini
  • Andrea Bettinelli
  • Ornella Milanesi
  • Marta Paiusco
  • Antonella Roggio
  • Phys Med.2020 Jul;76:134-141. S1120-1797(20)30161-7. doi: 10.1016/j.ejmp.2020.07.001.Epub 2020-07-13.

妊娠20週から36週＋6週の間の胎児心臓のスペクトルドップラーと組織ドップラーの両方を用いた左心室、右心室、心室間隔の充填時間と収縮期-拡張期時間指数の基準範囲

Reference ranges of filling time and systolic-to-diastolic time index of the left ventricle, right ventricle, and interventricular septum using both spectral and tissue Doppler of fetal heart between 20 and 36 + 6 weeks of gestation.
  • Alberto Borges Peixoto
  • Nathalie Jeanne Magioli Bravo-Valenzuela
  • Wellington P Martins
  • Rosiane Mattar
  • Antonio Fernandes Moron
  • David Baptista da Silva Pares
  • Gabriele Tonni
  • Edward Araujo Júnior
  • Eur. J. Obstet. Gynecol. Reprod. Biol..2020 Jul;252:366-372. S0301-2115(20)30459-0. doi: 10.1016/j.ejogrb.2020.07.017.Epub 2020-07-13.

北ドイツで生産される蜂蜜におけるピロリジジンアルカロイドの拡散と発生。特別な消費者グループのためのサイト間およびサイト内変動とリスク評価

Spread of and Occurrence of Pyrrolizidine Alkaloids in Regionally Produced Honeys from Northern Germany: Inter- and Intra-Site Variations and Risk Assessment for Special Consumer Groups.
  • Christoph Gottschalk
  • Florian Kaltner
  • Matthias Zimmermann
  • Rainer Korten
  • Oliver Morris
  • Karin Schwaiger
  • Manfred Gareis
  • Toxins (Basel).2020 Jul;12(7). E441. doi: 10.3390/toxins12070441.Epub 2020-07-07.

以前に導出された宿主遺伝子発現分類法により、南アジア集団における急性熱性呼吸器疾患の細菌性およびウイルス性病因が同定された

Previously Derived Host Gene Expression Classifiers Identify Bacterial and Viral Etiologies of Acute Febrile Respiratory Illness in a South Asian Population.
  • L Gayani Tillekeratne
  • Sunil Suchindran
  • Emily R Ko
  • Elizabeth A Petzold
  • Champica K Bodinayake
  • Ajith Nagahawatte
  • Vasantha Devasiri
  • Ruvini Kurukulasooriya
  • Bradly P Nicholson
  • Micah T McClain
  • Thomas W Burke
  • Ephraim L Tsalik
  • Ricardo Henao
  • Geoffrey S Ginsburg
  • Megan E Reller
  • Christopher W Woods
  • Open Forum Infect Dis.2020 Jun;7(6):ofaa194. ofaa194. doi: 10.1093/ofid/ofaa194.Epub 2020-05-26.

吸収性ゼラチンスポンジを用いた内視鏡的超音波ガイドコイル塞栓術は、胃静脈瘤の治療に従来のシアノアクリレート注射よりも優れているようです

Endoscopic Ultrasound-Guided Coil Embolization With Absorbable Gelatin Sponge Appears Superior to Traditional Cyanoacrylate Injection for the Treatment of Gastric Varices.
  • Ahmad Najdat Bazarbashi
  • Thomas J Wang
  • Pichamol Jirapinyo
  • Christopher C Thompson
  • Marvin Ryou
  • Clin Transl Gastroenterol.2020 May;11(5):e00175. 01720094-202005000-00008. doi: 10.14309/ctg.0000000000000175.

ゲノム解析およびin vitro解析を用いて発酵野菜から分離された潜在的なプロバイオティクス細菌Lactococcus raffinolactis WiKim0068の特性評価

Characterization of a potential probiotic bacterium Lactococcus raffinolactis WiKim0068 isolated from fermented vegetable using genomic and in vitro analyses.
  • Min Young Jung
  • Changsu Lee
  • Myung-Ji Seo
  • Seong Woon Roh
  • Se Hee Lee
  • BMC Microbiol..2020 May;20(1):136. 10.1186/s12866-020-01820-9. doi: 10.1186/s12866-020-01820-9.Epub 2020-05-27.

乳がん細胞株におけるサリノマイシンのメカニズムに関するトランスクリプトーム解析による洞察：ダサチニブとの相乗効果とエストロゲン受容体βの誘導

Transcriptomic insight into salinomycin mechanisms in breast cancer cell lines: synergistic effects with dasatinib and induction of estrogen receptor β.
  • Vanessa Bellat
  • Alice Verchère
  • Sally A Ashe
  • Benedict Law
  • BMC Cancer.2020 Jul;20(1):661. 10.1186/s12885-020-07134-3. doi: 10.1186/s12885-020-07134-3.Epub 2020-07-16.

マクロな心筋細胞ネットワークダイナミクスに対する交感神経の影響を光で探る

Optical Interrogation of Sympathetic Neuronal Effects on Macroscopic Cardiomyocyte Network Dynamics.
  • Rebecca-Ann B Burton
  • Jakub Tomek
  • Christina M Ambrosi
  • Hege E Larsen
  • Amy R Sharkey
  • Rebecca A Capel
  • Alexander D Corbett
  • Samuel Bilton
  • Aleksandra Klimas
  • Guy Stephens
  • Maegan Cremer
  • Samuel J Bose
  • Dan Li
  • Giuseppe Gallone
  • Neil Herring
  • Edward O Mann
  • Abhinav Kumar
  • Holger Kramer
  • Emilia Entcheva
  • David J Paterson
  • Gil Bub
  • iScience.2020 Jul;23(7):101334. S2589-0042(20)30521-6. doi: 10.1016/j.isci.2020.101334.Epub 2020-07-01.

テルペノイドインバソームの調製と低温透過電子顕微鏡によるキャラクタリゼーションに対する選択的活性を持つ

Preparation of Terpenoid-Invasomes with Selective Activity against and Characterization by Cryo Transmission Electron Microscopy.
  • Bernhard P Kaltschmidt
  • Inga Ennen
  • Johannes F W Greiner
  • Robin Dietsch
  • Anant Patel
  • Barbara Kaltschmidt
  • Christian Kaltschmidt
  • Andreas Hütten
  • Biomedicines.2020 May;8(5). E105. doi: 10.3390/biomedicines8050105.Epub 2020-05-01.

RET M918T生殖細胞変異を有する中国人患者における2b型多発性内分泌新生物症とそれに伴う混合髄様および濾胞性甲状腺癌

Multiple Endocrine Neoplasia Type 2b Associated Mixed Medullary and Follicular Thyroid Carcinoma in A Chinese Patient with RET M918T Germline Mutation.
  • Xiao-Ping Qi
  • Guo-Bing Lin
  • Bo Chen
  • Feng Li
  • Zhi-Lie Cao
  • Wei-Hui Zheng
  • Jian-Qiang Zhao
  • Endocr Metab Immune Disord Drug Targets.2020 Jul;EMIDDT-EPUB-108114. doi: 10.2174/1871530320666200713092633.Epub 2020-07-12.

前治療歴のある非小細胞肺癌患者におけるニボルマブに対する早期反応における統合F-FDG PET/MRIの予測値

Predictive value of integrated F-FDG PET/MRI in the early response to nivolumab in patients with previously treated non-small cell lung cancer.
  • Yukihiro Umeda
  • Miwa Morikawa
  • Masaki Anzai
  • Shingo Ameshima
  • Maiko Kadowaki
  • Yuko Waseda
  • Hiroko Shigemi
  • Tetsuya Tsujikawa
  • Yasushi Kiyono
  • Hidehiko Okazawa
  • Tamotsu Ishizuka
  • J Immunother Cancer.2020 Apr;8(1). e000349. doi: 10.1136/jitc-2019-000349.

Kigelia africanaの葉抽出物中の微量元素と化学組成分析のための質量分析技術に結合した最新のクロマトグラフィー法の探査

Exploration of Modern Chromatographic Methods Coupled to Mass Spectrometric Techniques for Trace Element and Chemical Composition Analyses in the Leaf Extracts of Kigelia africana.
  • Oladapo F Fagbohun
  • Jitcy S Joseph
  • Olusola A Salami
  • Titus A M Msagati
  • Biol Trace Elem Res.2020 Jul;10.1007/s12011-020-02274-w. doi: 10.1007/s12011-020-02274-w.Epub 2020-07-08.

無作為化脳卒中試験における中央判定者によるアウトカム評価。差分的分類と非差分的分類のシミュレーション

Outcome assessment by central adjudicators in randomised stroke trials: Simulation of differential and non-differential misclassification.
  • Peter J Godolphin
  • Philip M Bath
  • Christopher Partlett
  • Eivind Berge
  • Martin M Brown
  • Misha Eliasziw
  • Per Morten Sandset
  • Joaquín Serena
  • Alan A Montgomery
  • Eur Stroke J.2020 Jun;5(2):174-183. 10.1177_2396987320910047. doi: 10.1177/2396987320910047.Epub 2020-02-26.

HR+/HER2転移性乳がん患者において、初回内分泌療法対初回化学療法を受けた患者の生存率。フランスの集団ベースの研究

Survival in patients with HR+/HER2- metastatic breast cancer treated with initial endocrine therapy versus initial chemotherapy. A French population-based study.
  • Julien Simon
  • Marie Chaix
  • Oumar Billa
  • Ariane Mamguem Kamga
  • Patrick Roignot
  • Sylvain Ladoire
  • Charles Coutant
  • Patrick Arveux
  • Catherine Quantin
  • Tienhan Sandrine Dabakuyo-Yonli
  • Br. J. Cancer.2020 Jul;10.1038/s41416-020-0979-3. doi: 10.1038/s41416-020-0979-3.Epub 2020-07-17.

投与後の骨粗鬆症に対するオストホールの有効性を評価するための代謝バイオマーカーとパスウェイをハイスループットメタボロミクスで発見し、UPLC/Q-TOF-MSと多変量解析を組み合わせて骨粗鬆症に対するオストホールの潜在的なメカニズムを探る

High-Throughput Metabolomics Discovers Metabolic Biomarkers and Pathways to Evaluating the Efficacy and Exploring Potential Mechanisms of Osthole Against Osteoporosis Based on UPLC/Q-TOF-MS Coupled With Multivariate Data Analysis.
  • Zhenxing Si
  • Shifeng Zhou
  • Zilong Shen
  • Feiyu Luan
  • Front Pharmacol.2020;11:741. doi: 10.3389/fphar.2020.00741.Epub 2020-05-20.

小児および成人における4価デングワクチン候補の長期安全性と免疫原性：無作為化プラセボ対照第2相試験

Long-term safety and immunogenicity of a tetravalent dengue vaccine candidate in children and adults: a randomized, placebo-controlled, phase 2 study.
  • Chukiat Sirivichayakul
  • Elizabeth A Barranco-Santana
  • Inés Esquilín Rivera
  • Jennifer Kilbury
  • Marsha Raanan
  • Astrid Borkowski
  • Athanasia Papadimitriou
  • Derek Wallace
  • J. Infect. Dis..2020 Jul;jiaa406. doi: 10.1093/infdis/jiaa406.Epub 2020-07-13.

社会的説明責任は、貧困層のための無料の公的医療へのアクセスを向上させることができるだろうか？カンボジアにおける3つの健康衡平基金の構成の分析、2015-17年

Can social accountability improve access to free public health care for the poor? Analysis of three Health Equity Fund configurations in Cambodia, 2015-17.
  • Bart Jacobs
  • Sam Sam Oeun
  • Por Ir
  • Susan Rifkin
  • Wim Van Damme
  • Health Policy Plan.2020 Jul;35(6):635-645. 5828356. doi: 10.1093/heapol/czaa019.

COVID-19パンデミックに対する気象学的影響。南米の8つの深刻な影響を受けた地域を対象とした研究

Meteorological impact on the COVID-19 pandemic: A study across eight severely affected regions in South America.
  • Liting Zhu
  • Xiaobo Liu
  • Haining Huang
  • Ricardo David Avellán-Llaguno
  • Mauricio Manuel Llaguno Lazo
  • Aldo Gaggero
  • Ricardo Soto Rifo
  • Leandro Patiño
  • Magaly Valencia-Avellan
  • Benoit Diringer
  • Qiansheng Huang
  • Yong-Guan Zhu
  • Sci. Total Environ..2020 Jul;744:140881. S0048-9697(20)34410-7. doi: 10.1016/j.scitotenv.2020.140881.Epub 2020-07-11.

臨床的に実現可能な低レベルレーザー治療の適用が矯正歯の移動速度に及ぼす影響。三重盲検、分割口、無作為化比較試験

The effects of a clinically feasible application of low-level laser therapy on the rate of orthodontic tooth movement: A triple-blind, split-mouth, randomized controlled trial.
  • Dipika Mistry
  • Oyku Dalci
  • Spyridon N Papageorgiou
  • M Ali Darendeliler
  • Alexandra K Papadopoulou
  • Am J Orthod Dentofacial Orthop.2020 Apr;157(4):444-453. S0889-5406(19)30989-8. doi: 10.1016/j.ajodo.2019.12.005.

腎細胞癌患者における原発性および転移性病変のSPECT/CTイメージングを目的としたTc-PHC-102のマイクロドージング試験

A microdosing study with Tc-PHC-102 for the SPECT/CT imaging of primary and metastatic lesions in renal cell carcinoma patients.
  • Oana Cristina Kulterer
  • Sarah Pfaff
  • Wolfgang Wadsak
  • Nathalie Garstka
  • Mesut Remzi
  • Chrysoula Vraka
  • Lukas Nics
  • Franziska Bootz
  • Samuele Cazzamalli
  • Nikolaus Krall
  • Dario Neri
  • Alexander Robert Haug
  • J. Nucl. Med..2020 Jul;jnumed.120.245530. doi: 10.2967/jnumed.120.245530.Epub 2020-07-17.

呼吸窮迫症候群の早産児における低侵襲性界面活性剤投与失敗の危険因子

[Risk factors for minimally invasive surfactant administration failure in preterm infants with respiratory distress syndrome].
  • Hui-Qiang Liu
  • Xiao-Mei Tong
  • Tong-Yan Han
  • Hui Zhang
  • Ming Guo
  • Xue-Feng Zhang
  • Xin-Jian Liu
  • Xiang Zhang
  • Ming-Tao Zhang
  • Fang Liu
  • Li-Sha Bao
  • Jun Zheng
  • Xiu-Ying Tian
  • Qi Gao
  • Wan-Xian Zhang
  • Yang Duan
  • Fu-Qiang Sun
  • Wei Guo
  • Ling Li
  • Min Xiao
  • Wei-Li Liu
  • Rui Jiang
  • Zhongguo Dang Dai Er Ke Za Zhi.2020 Mar;22(3):231-237. 10.7499/j.issn.1008-8830.2020.03.010.

神経病理学的に確認されたレビー小体を伴う認知症とアルツハイマー型認知症を区別する重度の低スミア

Severe hyposmia distinguishes neuropathologically confirmed dementia with Lewy bodies from Alzheimer's disease dementia.
  • Thomas G Beach
  • Charles H Adler
  • Nan Zhang
  • Geidy E Serrano
  • Lucia I Sue
  • Erika Driver-Dunckley
  • Shayamal H Mehta
  • Edouard E Zamrini
  • Marwan N Sabbagh
  • Holly A Shill
  • Christine M Belden
  • David R Shprecher
  • Richard J Caselli
  • Eric M Reiman
  • Kathryn J Davis
  • Kathy E Long
  • Lisa R Nicholson
  • Anthony J Intorcia
  • Michael J Glass
  • Jessica E Walker
  • Michael M Callan
  • Javon C Oliver
  • Richard Arce
  • Richard C Gerkin
  • PLoS ONE.2020;15(4):e0231720. PONE-D-19-31747. doi: 10.1371/journal.pone.0231720.Epub 2020-04-22.

プロトカテキン酸サプリメントは、アレルギー性喘息マウスにおけるIL-4Rα-STAT6およびJagged 1/Jagged2-Notch1/Notch2経路を阻害することで、アレルギー性気道炎症を緩和する

Protocatechuic acid supplement alleviates allergic airway inflammation by inhibiting the IL-4Rα-STAT6 and Jagged 1/Jagged2-Notch1/Notch2 pathways in allergic asthmatic mice.
  • Qin Li
  • Yinfan Wu
  • Xingyue Guo
  • Ren Wang
  • Yuheng Mao
  • Yimin Zhao
  • Jinchao Zou
  • Chunwei Li
  • Yanqiu Chen
  • Yan Yang
  • Inflamm. Res..2020 Jul;10.1007/s00011-020-01379-1. doi: 10.1007/s00011-020-01379-1.Epub 2020-07-15.

高脂肪食マウスの腸内細菌叢を改善してsIgA産生を増強する乳酸菌カセイ発酵ブルーベリーポマース（FBP）の腸内分泌免疫グロブリンA（sIgA）産生増強作用について検討した

Lactobacillus casei-fermented blueberry pomace augments sIgA production in high-fat diet mice by improving intestinal microbiota.
  • Yuxin Cheng
  • Shuxin Tang
  • Yuting Huang
  • Fuqiang Liang
  • Yajing Fang
  • Siyi Pan
  • Ting Wu
  • Xiaoyun Xu
  • Food Funct.2020 Jul;doi: 10.1039/d0fo01119c.Epub 2020-07-09.

23遺伝子発現シグネチャー（myPath Melanoma）の蛍光その場ハイブリダイゼーションアッセイとシングルヌクレオチド多型アレイとのコンコーダンス解析による難治性黒色細胞性病変の解析。学術医療センターからの結果

Concordance Analysis of the 23-Gene Expression Signature (myPath Melanoma) With Fluorescence In Situ Hybridization Assay and Single Nucleotide Polymorphism Array in the Analysis of Challenging Melanocytic Lesions: Results From an Academic Medical Center.
  • Stephanie A Castillo
  • Anh K Pham
  • Alicia T Dagrosa
  • Shaofeng Yan
  • Dorothea T Barton
  • Joel A Lefferts
  • Konstantinos Linos
  • Am J Dermatopathol.2020 Jul;doi: 10.1097/DAD.0000000000001713.Epub 2020-07-14.

右スワイプ：出会い系アプリによる性的暴行の出現。オーストラリアの首都圏サービスにおける法医学検査の症例数の記述的遡及的監査

Swipe right: the emergence of dating-app facilitated sexual assault. A descriptive retrospective audit of forensic examination caseload in an Australian metropolitan service.
  • Janine Rowse
  • Caroline Bolt
  • Sanjeev Gaya
  • Forensic Sci Med Pathol.2020 Mar;16(1):71-77. 10.1007/s12024-019-00201-7. doi: 10.1007/s12024-019-00201-7.Epub 2020-02-06.

家畜廃水を異なる外因性誘導剤で処理した場合の、建設された湿地における抗生物質耐性遺伝子の応答。抗生物質と抗生物質耐性菌

Response of antibiotic resistance genes in constructed wetlands during treatment of livestock wastewater with different exogenous inducers: Antibiotic and antibiotic-resistant bacteria.
  • Lin Liu
  • Yu Xin
  • Xu Huang
  • Chaoxiang Liu
  • Bioresour. Technol..2020 Jul;314:123779. S0960-8524(20)31051-8. doi: 10.1016/j.biortech.2020.123779.Epub 2020-07-06.

SLC24A4における新規のナンセンス変異体が、パキスタンの家族における稀な形態のアメロゲ形成不全症を引き起こす

A novel nonsense variant in SLC24A4 causing a rare form of amelogenesis imperfecta in a Pakistani family.
  • Sher Alam Khan
  • Muhammad Adnan Khan
  • Nazif Muhammad
  • Hina Bashir
  • Niamat Khan
  • Noor Muhammad
  • Rüstem Yilmaz
  • Saadullah Khan
  • Naveed Wasif
  • BMC Med. Genet..2020 05;21(1):97. 10.1186/s12881-020-01038-6. doi: 10.1186/s12881-020-01038-6.Epub 2020-05-07.

ガントリースタティックカウチモーション（GsCM）法による乳房ブースト放射線治療の線量評価上の利点。リスクのある臓器への線量が減少し、線量指標が改善された

Dosimetric benefits of gantry-static couch-motion (GsCM) technique for breast boost radiation therapy: Reduced dose to organs-at-risk and improved dosimetric indices.
  • Gurtej S Gill
  • Raphael Y Jakubovic
  • Jameson Baker
  • Terry Button
  • Jenghwa Chang
  • J Appl Clin Med Phys.2020 Jul;doi: 10.1002/acm2.12969.Epub 2020-07-05.

脳内サイトカインが多い統合失調症患者では、脳内サイトカインが多い非統合失調症患者に比べてNF-κBの活性化が弱い

Nuclear factor kappa B activation appears weaker in schizophrenia patients with high brain cytokines than in non-schizophrenic controls with high brain cytokines.
  • Caitlin E Murphy
  • Adam J Lawther
  • Maree J Webster
  • Makoto Asai
  • Yuji Kondo
  • Mitsuyuki Matsumoto
  • Adam K Walker
  • Cynthia Shannon Weickert
  • J Neuroinflammation.2020 Jul;17(1):215. 10.1186/s12974-020-01890-6. doi: 10.1186/s12974-020-01890-6.Epub 2020-07-17.

致死性サイトカイン放出症候群における"小"腸管免疫病理は"大きな"役割を果たし、インターフェロン-γ、IL-17A、およびヤヌスキナーゼ阻害剤によるその調節

"Small" Intestinal Immunopathology Plays a "Big" Role in Lethal Cytokine Release Syndrome, and Its Modulation by Interferon-γ, IL-17A, and a Janus Kinase Inhibitor.
  • Shiv D Kale
  • Brittney N Mehrkens
  • Molly M Stegman
  • Bridget Kastelberg
  • Henry Carnes
  • Rachel J McNeill
  • Amy Rizzo
  • Saikumar V Karyala
  • Sheryl Coutermarsh-Ott
  • Jackie A Fretz
  • Ying Sun
  • Jonathan L Koff
  • Govindarajan Rajagopalan
  • Front Immunol.2020;11:1311. doi: 10.3389/fimmu.2020.01311.Epub 2020-06-26.

早産児の頭蓋変形および神経発達に及ぼすポジショニング枕の使用を6ヵ月齢まで継続することの効果。プロスペクティブケースコントロール研究

Effects of continued positioning pillow use until a corrected age of six months on cranial deformation and neurodevelopment in preterm infants: A prospective case-control study.
  • Yuu Uchio
  • Naoko Shima
  • Kaho Nakamura
  • Tetsuo Ikai
  • Osamu Nitta
  • Early Hum. Dev..2020 Jul;148:105137. S0378-3782(20)30270-X. doi: 10.1016/j.earlhumdev.2020.105137.Epub 2020-07-09.

応答面法を用いた限外ろ過膜を用いたキシロース還元酵素分離のための運転パラメータの最適化

Optimization of operating parameters for xylose reductase separation through ultrafiltration membrane using response surface methodology.
  • Santhana Krishnan
  • B Noor Suzana
  • Zularisam Abdul Wahid
  • Mohd Nasrullah
  • Mimi Sakinah Abdul Munaim
  • Mohd Fadhil Bin Md Din
  • Shazwin Mat Taib
  • Yu You Li
  • Biotechnol Rep (Amst).2020 Sep;27:e00498. S2215-017X(20)30051-5. doi: 10.1016/j.btre.2020.e00498.Epub 2020-06-29.

体格指数が25kg/m以上のステージII/III結腸癌患者に対する腹腔鏡下手術の開腹手術

Laparoscopic Open Surgery for Stage II/III Colon Cancer Patients With Body Mass Index >25 kg/m.
  • Keisuke Kazama
  • Masakatsu Numata
  • Toru Aoyama
  • Atsushi Onodeara
  • Kentaro Hara
  • Yosuke Atsumi
  • Hiroshi Tamagawa
  • Teni Godai
  • Hiroyuki Saeki
  • Yusuke Saugusa
  • Hironao Okamoto
  • Manabu Shiozawa
  • Takashi Oshima
  • Norio Yukawa
  • Munetaka Masuda
  • Yasushi Rino
  • In Vivo.2020 Jul-Aug;34(4):2079-2085. 34/4/2079. doi: 10.21873/invivo.12011.

アルカロイドであるボルダインの胃保護効果：非タンパク性スルフヒドリル基、プロスタノイドの関与、酸化ストレスに対する還元

Gastroprotective effect of the alkaloid boldine: Involvement of non-protein sulfhydryl groups, prostanoids and reduction on oxidative stress.
  • Thaise Boeing
  • Luisa Natália Bolda Mariano
  • Ana Caroline Dos Santos
  • Bianca Tolentino
  • Angela Cadorin Vargas
  • Priscila de Souza
  • Luciane Angela Nottar Nesello
  • Luísa Mota da Silva
  • Chem. Biol. Interact..2020 Jun;327:109166. S0009-2797(20)30409-9. doi: 10.1016/j.cbi.2020.109166.Epub 2020-06-09.

化合物を用いた新規抗トリパノゾーマ薬の開発に向けて、フタルアジノン系ホスホジエステラーゼ阻害剤の最適化をリードしています

Lead Optimization of Phthalazinone Phosphodiesterase Inhibitors as Novel Antitrypanosomal Compounds.
  • Irene G Salado
  • Abhimanyu K Singh
  • Carlos Moreno-Cinos
  • Guna Sakaine
  • Marco Siderius
  • Pieter Van der Veken
  • An Matheeussen
  • Tiffany van der Meer
  • Payman Sadek
  • Sheraz Gul
  • Louis Maes
  • Geert-Jan Sterk
  • Rob Leurs
  • David Brown
  • Koen Augustyns
  • J. Med. Chem..2020 Apr;63(7):3485-3507. doi: 10.1021/acs.jmedchem.9b00985.Epub 2020-03-26.

牡蠣 Crassostrea gigas (Thunberg, 1789) の生体内変換系におけるピレンとフルオレンによる応答の違い。分子・生化学的・組織学的アプローチ -第II部

Differential responses in the biotransformation systems of the oyster Crassostrea gigas (Thunberg, 1789) elicited by pyrene and fluorene: Molecular, biochemical and histological approach - Part II.
  • Isis Mayna Martins Dos Reis
  • Marília Nardelli Siebert
  • Flávia Lucena Zacchi
  • Jacó Joaquim Mattos
  • Fabrício Flores-Nunes
  • Guilherme de Toledo-Silva
  • Clei Endrigo Piazza
  • Márcia Caruso Bícego
  • Satie Taniguchi
  • Cláudio Manoel Rodrigues de Melo
  • Afonso Celso Dias Bainy
  • Aquat. Toxicol..2020 Jul;226:105565. S0166-445X(20)30315-5. doi: 10.1016/j.aquatox.2020.105565.Epub 2020-07-09.

異なる診断法に基づくリンパ系フィラリア症微小フィラリア症有病率推定値の標準化：システマティックレビューとメタアナリシス

Standardisation of lymphatic filariasis microfilaraemia prevalence estimates based on different diagnostic methods: a systematic review and meta-analysis.
  • Natalie V S Vinkeles Melchers
  • Luc E Coffeng
  • Sake J de Vlas
  • Wilma A Stolk
  • Parasit Vectors.2020 Jun;13(1):302. 10.1186/s13071-020-04144-9. doi: 10.1186/s13071-020-04144-9.Epub 2020-06-11.

HLBによる移植片接種に対する反応の縦断的トランスクリプトーム、プロテオーム、メタボローム解析

Longitudinal Transcriptomic, Proteomic, and Metabolomic Analysis of Response to Graft Inoculation by .
  • John S Ramsey
  • Elizabeth L Chin
  • Juan D Chavez
  • Surya Saha
  • Darya Mischuk
  • Jaclyn Mahoney
  • Jared Mohr
  • Faith M Robison
  • Elizabeth Mitrovic
  • Yimin Xu
  • Susan R Strickler
  • Noe Fernandez
  • Xuefei Zhong
  • MaryLou Polek
  • Kris E Godfrey
  • James J Giovannoni
  • Lukas A Mueller
  • Carolyn M Slupsky
  • James E Bruce
  • Michelle Heck
  • J. Proteome Res..2020 Jun;19(6):2247-2263. doi: 10.1021/acs.jproteome.9b00802.Epub 2020-05-12.

ゼブラフィッシュ変異体のトランスクリプトーム解析により、Atoh7に依存した遺伝的ネットワークが明らかになり、ヒトの眼疾患に影響を与える可能性があることが明らかになりました

Transcriptome analysis of the zebrafish Mutant, , highlights Atoh7-dependent genetic networks with potential implications for human eye diseases.
  • Giuseppina Covello
  • Fernando J Rossello
  • Michele Filosi
  • Felipe Gajardo
  • Anne-Laure Duchemin
  • Beatrice F Tremonti
  • Michael Eichenlaub
  • Jose M Polo
  • David Powell
  • John Ngai
  • Miguel L Allende
  • Enrico Domenici
  • Mirana Ramialison
  • Lucia Poggi
  • FASEB Bioadv.2020 Jul;2(7):434-448. FBA21146. doi: 10.1096/fba.2020-00030.Epub 2020-06-27.

サイロトキシン症に曝露される期間は、危険なAIT患者の死亡率を増加させる：早期の甲状腺摘出術の役割

Duration of exposure to thyrotoxicosis increases mortality of compromised AIT patients: the role of early thyroidectomy.
  • Daniele Cappellani
  • Piermarco Papini
  • Agostino Maria Di Certo
  • Riccardo Morganti
  • Claudio Urbani
  • Luca Manetti
  • Maria Laura Tanda
  • Giada Cosentino
  • Giulia Marconcini
  • Gabriele Materazzi
  • Enio Martino
  • Luigi Bartalena
  • Fausto Bogazzi
  • J. Clin. Endocrinol. Metab..2020 Jul;dgaa464. doi: 10.1210/clinem/dgaa464.Epub 2020-07-17.

ulliparous女性における銅T380A子宮内装置挿入の3時間前に投与された膣ミソプロストールと膣ディノプロストンの比較効果。無作為化対照試験

Comparative Efficacy of Vaginal Misoprostol vs Vaginal Dinoprostone Administered 3 Hours Prior to Copper T380A Intrauterine Device Insertion in Nulliparous Women: A Randomized Controlled Trial.
  • Ahmed Samy Ali Ashour
  • Mohamed El Sharkawy
  • Ahmed Said Ali
  • Nawal Hamdy Ahmed Keshta
  • Hanan Barakat Abu Elyazid Shatat
  • Mohamed El Mahy
  • J Pediatr Adolesc Gynecol.2020 Apr;S1083-3188(20)30206-0. doi: 10.1016/j.jpag.2020.04.004.Epub 2020-04-21.

内視鏡的超音波ガイド下胆嚢ドレナージにおける金属ステントとルーメンのフランジが原因となった幽門環閉塞の一例。症例報告

An unusual complication of pyloric ring obstruction caused by flange of lumen apposing metal stent in endoscopic ultrasound-guided gallbladder drainage: A case report.
  • Seung Young Seo
  • Chang Hun Lee
  • In Hee Kim
  • Sang Wook Kim
  • Seung Ok Lee
  • Soo Teik Lee
  • Seong-Hun Kim
  • Medicine (Baltimore).2020 Jul;99(27):e21017. 00005792-202007020-00102. doi: 10.1097/MD.0000000000021017.

沿岸オニヒトデ2種のシーロミック液中の微生物相とヘリコバクター関連種の特徴の解明

Microbiota in the coelomic fluid of two common coastal starfish species and characterization of an abundant Helicobacter-related taxon.
  • Satoshi Nakagawa
  • Hikari Saito
  • Akihiro Tame
  • Miho Hirai
  • Hideyuki Yamaguchi
  • Takashi Sunata
  • Masanori Aida
  • Hisashi Muto
  • Shigeki Sawayama
  • Yoshihiro Takaki
  • Sci Rep.2017 08;7(1):8764. 10.1038/s41598-017-09355-2. doi: 10.1038/s41598-017-09355-2.Epub 2017-08-18.

タンザニアの異なる土壌タイプと作付けパターンの下でタバコの植物の根圏細菌の多様性と土壌肥沃度をリンクしています。パイロット研究

Linking rhizosphere bacterial diversity and soil fertility in tobacco plants under different soil types and cropping pattern in Tanzania: A pilot study.
  • Jacob Bulenga Lisuma
  • Zavuga Zuberi
  • Patrick Alois Ndakidemi
  • Ernest Rashid Mbega
  • Heliyon.2020 Jul;6(7):e04278. S2405-8440(20)31122-1. doi: 10.1016/j.heliyon.2020.e04278.Epub 2020-07-08.

(5-((4-(ピリジン-3-イル)ピリミジン-2-イル)アミノ)-1H-インドール足場を有するメチレンヒドラジン-1-カルボキサミド誘導体の設計、合成および生物学的評価。新規なCDK9阻害剤の可能性

Design, synthesis and biological evaluation of methylenehydrazine-1-carboxamide derivatives with (5-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)-1H-indole scaffold: Novel potential CDK9 inhibitors.
  • Hongyu Hu
  • Jun Wu
  • Mingtao Ao
  • Xiaoping Zhou
  • Boqun Li
  • Zhenzhen Cui
  • Tong Wu
  • Lijuan Wang
  • Yuhua Xue
  • Zhen Wu
  • Meijuan Fang
  • Bioorg. Chem..2020 Jun;102:104064. S0045-2068(20)31361-4. doi: 10.1016/j.bioorg.2020.104064.Epub 2020-06-30.

米国メリーランド州ボルチモアのシスジェンダー女性セックスワーカーのコホートにおけるInternalized Sex Work Stigma Scaleの確認的因子分析と構成要件の妥当性

Confirmatory Factor Analysis and Construct Validity of the Internalized Sex Work Stigma Scale among a Cohort of Cisgender Female Sex Workers in Baltimore, Maryland, United States.
  • Catherine Tomko
  • Danielle Friedman Nestadt
  • Saba Rouhani
  • Bradley E Silberzahn
  • Katherine Haney
  • Ju Nyeong Park
  • Noya Galai
  • Carmen H Logie
  • Susan G Sherman
  • J Sex Res.2020 May;:1-11. doi: 10.1080/00224499.2020.1755821.Epub 2020-05-13.

膠芽腫と新たに診断された患者を対象とした、テモゾロミドとの併用、または放射線療法およびテモゾロミドとの併用によるブパルリシブの第I相非盲検多施設共同試験

Phase I, open-label, multicentre study of buparlisib in combination with temozolomide or with concomitant radiation therapy and temozolomide in patients with newly diagnosed glioblastoma.
  • Patrick Yung Wen
  • Jordi A Rodon
  • Warren Mason
  • Joseph T Beck
  • John DeGroot
  • Valerie Donnet
  • David Mills
  • Mona El-Hashimy
  • Mark Rosenthal
  • ESMO Open.2020 Jul;5(4). e000673. doi: 10.1136/esmoopen-2020-000673.

1型糖尿病の小児および青年における低血糖エピソードに対する単純な炭水化物の効果の比較。糖尿病キャンプでの無作為化研究

Comparison of the Effectiveness of Simple Carbohydrates on Hypoglycemic Episodes in Children and Adolescents with Type 1 Diabetes Mellitus: A Randomized Study in a Diabetes Camp.
  • İbrahim Mert Erbaş
  • Ayhan Abacı
  • Ahmet Anık
  • Erdem Şimşek
  • Hale Ünver Tuhan
  • Cemil Koçyiğit
  • Melek Yıldİz
  • Bumin Nuri Dündar
  • Ece Böber
  • Gönül Çatlı
  • Pediatr Diabetes.2020 Jul;doi: 10.1111/pedi.13077.Epub 2020-07-13.

臨床的に定義された痛風患者を対象としたサブタイプ特異的痛風感受性遺伝子座とその選択圧力の富化、およびサブタイプのゲノムワイドメタアナリシスによって同定された

Subtype-specific gout susceptibility loci and enrichment of selection pressure on and identified by subtype genome-wide meta-analyses of clinically defined gout patients.
  • Akiyoshi Nakayama
  • Masahiro Nakatochi
  • Yusuke Kawamura
  • Ken Yamamoto
  • Hirofumi Nakaoka
  • Seiko Shimizu
  • Toshihide Higashino
  • Teruhide Koyama
  • Asahi Hishida
  • Kiyonori Kuriki
  • Miki Watanabe
  • Toru Shimizu
  • Keiko Ooyama
  • Hiroshi Ooyama
  • Mitsuo Nagase
  • Yuji Hidaka
  • Daisuke Matsui
  • Takashi Tamura
  • Takeshi Nishiyama
  • Chisato Shimanoe
  • Sakurako Katsuura-Kamano
  • Naoyuki Takashima
  • Yuya Shirai
  • Makoto Kawaguchi
  • Mikiya Takao
  • Ryo Sugiyama
  • Yuzo Takada
  • Takahiro Nakamura
  • Hiroshi Nakashima
  • Masashi Tsunoda
  • Inaho Danjoh
  • Atsushi Hozawa
  • Kazuyoshi Hosomichi
  • Yu Toyoda
  • Yu Kubota
  • Tappei Takada
  • Hiroshi Suzuki
  • Blanka Stiburkova
  • Tanya J Major
  • Tony R Merriman
  • Nagato Kuriyama
  • Haruo Mikami
  • Toshiro Takezaki
  • Keitaro Matsuo
  • Sadao Suzuki
  • Tatsuo Hosoya
  • Yoichiro Kamatani
  • Michiaki Kubo
  • Kimiyoshi Ichida
  • Kenji Wakai
  • Ituro Inoue
  • Yukinori Okada
  • Nariyoshi Shinomiya
  • Hirotaka Matsuo
  • Ann. Rheum. Dis..2020 05;79(5):657-665. annrheumdis-2019-216644. doi: 10.1136/annrheumdis-2019-216644.Epub 2020-04-01.

ヒト赤血球のヒ素とセレン酸塩の取り込みと隔離。セレノビス(S-グルタチオニル)アルジニウムイオンのヒト細胞内での形成の証拠

Human Red Blood Cell Uptake and Sequestration of Arsenite and Selenite: Evidence of Seleno-bis(S-glutathionyl) Arsinium Ion Formation in Human Cells.
  • Gurnit Kaur
  • Warda Javed
  • Olena Ponomarenko
  • Kamran Shekh
  • Diane P Swanlund
  • Janet R Zhou
  • Kelly L Summers
  • Angela Casini
  • Margot Wenzel
  • Joseph R Casey
  • Emmanuelle Cordat
  • Ingrid J Pickering
  • Graham N George
  • Elaine M Leslie
  • Biochem. Pharmacol..2020 Jul;:114141. S0006-2952(20)30377-4. doi: 10.1016/j.bcp.2020.114141.Epub 2020-07-08.

赤血球あたりの胎児ヘモグロビン定量により、鎌状赤血球症における保護閾値を決定することができる

Fetal hemoglobin quantification per red blood cell allows to determine protective thresholds in sickle cell disease.
  • Nicolas Hebert
  • Marie Georgine Rakotoson
  • Gwellaouen Bodivit
  • Etienne Audureau
  • Laura Bencheikh
  • Laurent Kiger
  • Nadia Oubaya
  • Sadaf Pakdaman
  • Mehdi Sakka
  • Gaetana Di Liberto
  • Philippe Chadebech
  • Benoit Vingert
  • France Pirenne
  • Frédéric Galactéros
  • Marie Cambot
  • Pablo Bartolucci
  • Am. J. Hematol..2020 Jul;doi: 10.1002/ajh.25937.Epub 2020-07-18.

乳様突起気管置換術は顔面管の寸法と顔面鼓膜セグメントと粘膜の距離、および側方半円管と粘膜の距離に影響を与えるか？

Does Mastoid Pneumatization Affect Facial Canal Dimensions and Distances of Facial Tympanic Segment-Scutum and Lateral Semicircular Canal-Scutum?
  • Mikail Inal
  • Nuray Bayar Muluk
  • Neşe Asal
  • Mehmet Hamdi Şahan
  • Gökçe Şimşek
  • Osman Kürşat Arıkan
  • J Comput Assist Tomogr.2020 May/Jun;44(3):380-385. doi: 10.1097/RCT.0000000000000992.

子宮頸がん患者の生存期間におけるMMP-2、MMP-9、MMP-14、TIMP-1、TIMP-2、およびVEGF-Aの腫瘍性および間質性発現：競合リスク分析

Tumoral and stromal expression of MMP-2, MMP-9, MMP-14, TIMP-1, TIMP-2, and VEGF-A in cervical cancer patient survival: a competing risk analysis.
  • Jordana Maria Azevedo Martins
  • Silvia Helena Rabelo-Santos
  • Maria Cristina do Amaral Westin
  • Luiz Carlos Zeferino
  • BMC Cancer.2020 Jul;20(1):660. 10.1186/s12885-020-07150-3. doi: 10.1186/s12885-020-07150-3.Epub 2020-07-15.

PDGFA-associated protein 1は、成熟Bリンパ球をストレスによる細胞死から保護し、抗体遺伝子の多様化を促進します

PDGFA-associated protein 1 protects mature B lymphocytes from stress-induced cell death and promotes antibody gene diversification.
  • Verónica Delgado-Benito
  • Maria Berruezo-Llacuna
  • Robert Altwasser
  • Wiebke Winkler
  • Devakumar Sundaravinayagam
  • Sandhya Balasubramanian
  • Marieta Caganova
  • Robin Graf
  • Ali Rahjouei
  • Marie-Thérèse Henke
  • Madlen Driesner
  • Lisa Keller
  • Alessandro Prigione
  • Martin Janz
  • Altuna Akalin
  • Michela Di Virgilio
  • J. Exp. Med..2020 Oct;217(10). e20200137. doi: 10.1084/jem.20200137.

肺癌治療のためのシスプラチンを担持したキトサンアルギン酸ナノポーラスキャリアの開発、体外での特性評価、および生体内毒性評価

Development, In Vitro Characterization, and In Vivo Toxicity Evaluation of Chitosan-Alginate Nanoporous Carriers Loaded with Cisplatin for Lung Cancer Treatment.
  • Mo'tasem M Alsmadi
  • Rana M Obaidat
  • Mohammad Alnaief
  • Borhan Aldeen Albiss
  • Nabil Hailat
  • AAPS PharmSciTech.2020 Jul;21(5):191. 10.1208/s12249-020-01735-8. doi: 10.1208/s12249-020-01735-8.Epub 2020-07-13.

フードパントリー利用者の喫煙有病率と食料不安に対する禁煙プログラムの影響 - 実用的クラスター無作為化比較試験のための研究プロトコル

Impact of a smoking cessation program on smoking prevalence and food security among food pantry users - a study protocol for a pragmatic cluster randomised controlled trial.
  • Anja Simmet
  • Michael Teut
  • Romy Schleicher
  • Andreas Bschaden
  • Nanette Stroebele-Benschop
  • BMC Public Health.2020 Jul;20(1):1124. 10.1186/s12889-020-09232-0. doi: 10.1186/s12889-020-09232-0.Epub 2020-07-17.

経鼻的フルニソリドは、マウスの肺のシリカ粒子によって引き起こされる病理学的変化を抑制します

Intranasal Flunisolide Suppresses Pathological Alterations Caused by Silica Particles in the Lungs of Mice.
  • Tatiana Paula Teixeira Ferreira
  • Januário Gomes Mourão E Lima
  • Francisco Alves Farias-Filho
  • Yago Amigo Pinho Jannini de Sá
  • Ana Carolina Santos de Arantes
  • Fernanda Verdini Guimarães
  • Vinicius de Frias Carvalho
  • Cory Hogaboam
  • John Wallace
  • Marco Aurélio Martins
  • Patrícia Machado Rodrigues E Silva
  • Front Endocrinol (Lausanne).2020;11:388. doi: 10.3389/fendo.2020.00388.Epub 2020-06-17.

体外ガス発生を利用したアンコイルド・ライス・ストローの品質向上およびラムナル消化率向上のためのラムナル・クラブトリー陰性酵母とクラブトリー陽性酵母の比較効果

Comparison Effects of Ruminal Crabtree-Negative Yeasts and Crabtree-Positive Yeasts for Improving Ensiled Rice Straw Quality and Ruminal Digestion Using In Vitro Gas Production.
  • Chanon Suntara
  • Anusorn Cherdthong
  • Suthipong Uriyapongson
  • Metha Wanapat
  • Pin Chanjula
  • J Fungi (Basel).2020 Jul;6(3). E109. doi: 10.3390/jof6030109.Epub 2020-07-15.

豚糞尿の高固形分嫌気性消化に及ぼすナノバブル水の効果。消化安定性、メタン生成性能、および関連メカニズムに焦点を当てる

Effect of nano-bubble water on high solid anaerobic digestion of pig manure: Focus on digestion stability, methanogenesis performance and related mechanisms.
  • Yujie Fan
  • Zhongfang Lei
  • Xiaojing Yang
  • Motoyoshi Kobayashi
  • Yasuhisa Adachi
  • Zhenya Zhang
  • Kazuya Shimizu
  • Bioresour. Technol..2020 Jul;315:123793. S0960-8524(20)31065-8. doi: 10.1016/j.biortech.2020.123793.Epub 2020-07-08.

抗酸化剤とプレバイオティクスの併用は、どちらか一方の単剤療法よりも、去勢雄性ラットの認知機能改善に大きな効果を発揮します

A combination of an antioxidant with a prebiotic exerts greater efficacy than either as a monotherapy on cognitive improvement in castrated-obese male rats.
  • Titikorn Chunchai
  • Puntarik Keawtep
  • Apiwan Arinno
  • Napatsorn Saiyasit
  • Dillon Prus
  • Nattayaporn Apaijai
  • Wasana Pratchayasakul
  • Nipon Chattipakorn
  • Siriporn C Chattipakorn
  • Metab Brain Dis.2020 Jul;10.1007/s11011-020-00603-5. doi: 10.1007/s11011-020-00603-5.Epub 2020-07-16.

全身照射と血液または骨髄移植後の乳がんリスク。血液または骨髄移植生存者の研究報告

Total Body Irradiation and Risk of Breast Cancer After Blood or Marrow Transplantation: A Blood or Marrow Transplantation Survivor Study Report.
  • Andrew M McDonald
  • Yanjun Chen
  • Jessica Wu
  • Lindsey Hageman
  • Liton Francisco
  • Michelle Kung
  • F Lennie Wong
  • Emily Ness
  • Wendy Landier
  • Kevin Battles
  • Donna Salzman
  • Daniel J Weisdorf
  • Stephen J Forman
  • Mukta Arora
  • Saro H Armenian
  • Smita Bhatia
  • J. Clin. Oncol..2020 Jul;:JCO2000231. doi: 10.1200/JCO.20.00231.Epub 2020-07-16.

嗅球摘出マウスの視床下部におけるドパミンD受容体の過敏性

Dopamine D receptor supersensitivity in the hypothalamus of olfactory bulbectomized mice.
  • Kohei Takahashi
  • Osamu Nakagawasai
  • Takeharu Nakajima
  • Myu Okubo
  • Yuki Nishimura
  • Wakana Sakuma
  • Ryota Yamagata
  • Wataru Nemoto
  • Kazuya Miyagawa
  • Kazuhiro Kurokawa
  • Atsumi Mochida-Saito
  • Minoru Tsuji
  • Hiroshi Takeda
  • Takeshi Tadano
  • Koichi Tan-No
  • Brain Res..2020 Jul;1746:147015. S0006-8993(20)30371-1. doi: 10.1016/j.brainres.2020.147015.Epub 2020-07-13.

閉塞性睡眠時無呼吸と関連した術後重症イベント。麻酔と睡眠医学の閉塞性睡眠時無呼吸のレジストリの学会からの結果

Postoperative Critical Events Associated With Obstructive Sleep Apnea: Results From the Society of Anesthesia and Sleep Medicine Obstructive Sleep Apnea Registry.
  • Norman Bolden
  • Karen L Posner
  • Karen B Domino
  • Dennis Auckley
  • Jonathan L Benumof
  • Seth T Herway
  • David Hillman
  • Shawn L Mincer
  • Frank Overdyk
  • David J Samuels
  • Lindsay L Warner
  • Toby N Weingarten
  • Frances Chung
  • Anesth. Analg..2020 Jul;doi: 10.1213/ANE.0000000000005005.Epub 2020-07-14.

ヒト羊膜間葉系幹細胞は、アポトーシスと酸化ストレスを抑制することで、ブスルファン誘発性精巣毒性を有するマウスの精子形成を回復させる

Human amnion mesenchymal stem cells restore spermatogenesis in mice with busulfan-induced testis toxicity by inhibiting apoptosis and oxidative stress.
  • Chunfeng Qian
  • Qingxia Meng
  • Jiafeng Lu
  • Liya Zhang
  • Hong Li
  • Boxian Huang
  • Stem Cell Res Ther.2020 Jul;11(1):290. 10.1186/s13287-020-01803-7. doi: 10.1186/s13287-020-01803-7.Epub 2020-07-16.

神経炎症はレビー小体型疾患およびα-シヌクレイン遺伝子導入モデルにおけるT細胞の浸潤と関連している

Neuroinflammation is associated with infiltration of T cells in Lewy body disease and α-synuclein transgenic models.
  • Michiyo Iba
  • Changyoun Kim
  • Michelle Sallin
  • Somin Kwon
  • Anjali Verma
  • Cassia Overk
  • Robert A Rissman
  • Ranjan Sen
  • Jyoti Misra Sen
  • Eliezer Masliah
  • J Neuroinflammation.2020 Jul;17(1):214. 10.1186/s12974-020-01888-0. doi: 10.1186/s12974-020-01888-0.Epub 2020-07-17.

単純ヘルペスウイルス2型は神経成長因子に依存した感染時の神経突起の伸長反発に対抗する

Herpes Simplex Virus Type 2 Counteracts Neurite Outgrowth Repulsion During Infection In A Nerve Growth Factor-Dependent Manner.
  • Kai A Kropp
  • Alberto Domingo López-Muñoz
  • Birgit Ritter
  • Rocío Martín
  • Alberto Rastrojo
  • Sangar Srivaratharajan
  • Katinka Döhner
  • Akshay Dhingra
  • Julia S Czechowicz
  • Claus-Henning Nagel
  • Beate Sodeik
  • Antonio Alcami
  • Abel Viejo-Borbolla
  • J. Virol..2020 Jul;JVI.01370-20. doi: 10.1128/JVI.01370-20.Epub 2020-07-15.

播種性Talaromyces marneffei感染症は、STAT3変異を有する乳児に多発性腸管穿孔とびまん性肝肉芽腫性炎症を呈した症例である

Disseminated Talaromyces marneffei infection presenting as multiple intestinal perforations and diffuse hepatic granulomatous inflammation in an infant with STAT3 mutation: a case report.
  • Mianluan Pan
  • Ye Qiu
  • Wen Zeng
  • Shudan Tang
  • Xuan Wei
  • Jianquan Zhang
  • BMC Infect. Dis..2020 Jun;20(1):394. 10.1186/s12879-020-05113-4. doi: 10.1186/s12879-020-05113-4.Epub 2020-06-03.

良性適応の子宮摘出術におけるシングルサイトロボット、マルチポートロボット、従来の腹腔鏡下手術の手術成績の比較

A Comparison of Surgical Outcomes between Single-Site Robotic, Multiport Robotic and Conventional Laparoscopic Techniques in Performing Hysterectomy for Benign Indications.
  • Natasha Gupta
  • D O Miranda Blevins
  • Jenny Holcombe
  • Robert Scott Furr
  • Gynecol Minim Invasive Ther.2020 Apr-Jun;9(2):59-63. GMIT-9-59. doi: 10.4103/GMIT.GMIT_68_19.Epub 2020-04-28.

高齢化社会を迎えた日本における最近の精巣悪性腫瘍の動向：2012年～2015年の病院別がん登録データを用いた大規模研究

Recent malignant testicular tumor trend in Japan, a country with an aging population: a large-scale study of 2012-2015 hospital-based cancer registry data.
  • Kosuke Kojo
  • Koji Kawai
  • Takashi Kawahara
  • Tomokazu Kimura
  • Shuya Kandori
  • Yoshiyuki Nagumo
  • Satoshi Nitta
  • Takahiro Kojima
  • Ayako Okuyama
  • Takahiro Higashi
  • Hiroyuki Nishiyama
  • Jpn. J. Clin. Oncol..2020 Jul;hyaa110. doi: 10.1093/jjco/hyaa110.Epub 2020-07-06.

腎移植患者における高悪性度扁平上皮内病変のリスクは、免疫力のない対照者と比較して、肛門の高悪性度扁平上皮内病変のリスクが高い

Risk of anal high-grade squamous intraepithelial lesions among renal transplant recipients compared with immunocompetent controls.
  • H K Larsen
  • M Hædersdal
  • L T Thomsen
  • R Hertzum-Larsen
  • T T Lok
  • J Bonde
  • S S Sørensen
  • J M Hansen
  • J M Palefsky
  • S K Kjær
  • Clin. Infect. Dis..2020 Jun;ciaa781. doi: 10.1093/cid/ciaa781.Epub 2020-06-16.

急性骨髄性白血病患者の芽球細胞におけるScl転写因子複合体タンパク質発現パターンとATRA誘導分化に対するLiClの効果との関係の解析

Analysis of the relationship between Scl transcription factor complex protein expression patterns and the effects of LiCl on ATRA-induced differentiation in blast cells from patients with acute myeloid leukemia.
  • Anna M Rice
  • Kathleen M Holtz
  • Judith Karp
  • Sandra Rollins
  • Alan C Sartorelli
  • Leuk. Res..2004 Nov;28(11):1227-37. S0145212604001237. doi: 10.1016/j.leukres.2004.03.017.

マダニ（Haemaphysalis longicornis）に咬まれた際の宿主皮膚におけるタンパク質発現レベルとリン酸化レベルの包括的な解析

Comprehensive analysis of protein expression levels and phosphorylation levels in host skin in response to tick (Haemaphysalis longicornis) bite.
  • Xiaoli Zhang
  • Baowen Zhang
  • Abolfazl Masoudi
  • Xiaoshuang Wang
  • Xiaomin Xue
  • Mengxue Li
  • Qi Xiao
  • Minjing Wang
  • Jingze Liu
  • Hui Wang
  • J Proteomics.2020 Jul;:103898. S1874-3919(20)30266-9. doi: 10.1016/j.jprot.2020.103898.Epub 2020-07-15.

研究パートナーとして患者を参加させることは、コミュニケーション・スキル研修プログラム（KOKOS-Rheuma）の開発と評価に例示されている

Involving patients as research partners exemplified by the development and evaluation of a communication-skills training programme (KOKOS-Rheuma).
  • A C Schöpf-Lazzarino
  • P Böhm
  • U Garske
  • M Schlöffel
  • A Stoye
  • J Lamprecht
  • W Mau
  • E Farin
  • Z Rheumatol.2020 Jul;10.1007/s00393-020-00839-7. doi: 10.1007/s00393-020-00839-7.Epub 2020-07-16.

Covid-19入院前のICu患者における免疫調節薬の再利用-mulTi-Arm治療試験-再利用薬(TACTIC-R)を用いたCovid-19入院前のICu患者を対象とした試験。無作為化比較試験の試験計画書の構造化された要約

Repurposed immunomodulatory drugs for Covid-19 in pre-ICu patients - mulTi-Arm Therapeutic study in pre-ICu patients admitted with Covid-19 - Repurposed Drugs (TACTIC-R): A structured summary of a study protocol for a randomised controlled trial.
  • Spoorthy Kulkarni
  • Marie Fisk
  • Michalis Kostapanos
  • Edward Banham-Hall
  • Simon Bond
  • Elena Hernan-Sancho
  • Sam Norton
  • Joseph Cheriyan
  • Andrew Cope
  • James Galloway
  • Frances Hall
  • David Jayne
  • Ian B Wilkinson
  • Trials.2020 Jul;21(1):626. 10.1186/s13063-020-04535-4. doi: 10.1186/s13063-020-04535-4.Epub 2020-07-08.

血行動態的に有意な冠動脈疾患診断のためのストレスダイナミック心筋CT灌流の心筋血流解析。相対パラメータ最適化の臨床的価値

Myocardial blood flow analysis of stress dynamic myocardial CT perfusion for hemodynamically significant coronary artery disease diagnosis: The clinical value of relative parameter optimization.
  • Yan Yi
  • Cheng Xu
  • Wei Wu
  • Yun Wang
  • Yu-Mei Li
  • Zhu-Jun Shen
  • Zheng-Yu Jin
  • Yi-Ning Wang
  • J Cardiovasc Comput Tomogr.2019 Oct;S1934-5925(19)30173-X. doi: 10.1016/j.jcct.2019.10.001.Epub 2019-10-10.

個人用保護具が病院前提供者による小児救急処置のパフォーマンスに与える影響

Impact of Personal Protective Equipment on the Performance of Emergency Pediatric Procedures by Prehospital Providers.
  • Maybelle Kou
  • Aaron J Donoghue
  • Helen Stacks
  • Adam Kochman
  • Meghan Semiao
  • Mark Nash
  • David Siegel
  • Lawrence Ku
  • Julie Debski
  • Jia-Yuh Chen
  • Gaurav Sharma
  • Leigh Gosnell
  • Steven Krug
  • Mark D Adler
  • Disaster Med Public Health Prep.2020 May;:1-21. S1935789320001287. doi: 10.1017/dmp.2020.128.Epub 2020-05-11.

ルイス酸触媒によるプロパルギルアルコールと(E)-3-アミノ-3-フェニルアクリロニトリルのアニュレーションを介した1,6-ジヒドロピリジン-3-カルボニトリル誘導体の合成

Synthesis of 1,6-Dihydropyridine-3-carbonitrile Derivatives via Lewis Acid-Catalyzed Annulation of Propargylic Alcohols with (E)-3-amino-3-phenylacrylonitriles.
  • Li-Juan Du
  • Yuecheng Zhang
  • Hong-Yu Zhang
  • Guohui Yin
  • Xiao-Yan Wang
  • Jiquan Zhao
  • Ya-Ping Han
  • J. Org. Chem..2020 Jul;doi: 10.1021/acs.joc.0c01171.Epub 2020-07-15.

抗生物質デリバリービークル（ADV）としてのナノ粒子は、MRSAおよび他のMDR細菌病原体による耐性を克服する：手榴弾仮説

Nanoparticles as antibiotic-delivery vehicles (ADVs) overcome resistance by MRSA and other MDR bacterial pathogens: the grenade hypothesis.
  • Amjed Alabresm
  • Yung Pin Chen
  • Savannah Wichter-Chandler
  • Jamie Lead
  • Brian C Benicewicz
  • Alan W Decho
  • J Glob Antimicrob Resist.2020 Jul;S2213-7165(20)30168-5. doi: 10.1016/j.jgar.2020.06.023.Epub 2020-07-09.

RobotiX Mentorバーチャルリアリティシミュレーションプラットフォーム上でのロボット手術の基礎（FRS）カリキュラムの有効性を実証する

Demonstrating the effectiveness of the fundamentals of robotic surgery (FRS) curriculum on the RobotiX Mentor Virtual Reality Simulation Platform.
  • John Rhodes Martin
  • Dimitrios Stefanidis
  • Ryan P Dorin
  • Alvin C Goh
  • Richard M Satava
  • Jeffrey S Levy
  • J Robot Surg.2020 May;10.1007/s11701-020-01085-4. doi: 10.1007/s11701-020-01085-4.Epub 2020-05-14.

大豆粕の熱機械的および酵素促進処理は、離乳期の豚における試験管内でのタンパク質消化速度とタンパク質および アミノ酸消化率を向上させた

Thermo-mechanical and enzyme-facilitated processing of soybean meal enhanced in vitro kinetics of protein digestion and protein and amino acid digestibility in weaned pigs.
  • Mai Anh Ton Nu
  • Ingrid Lupatsch
  • Joaquin S Zannatta
  • Hagen Schulze
  • Ruurd T Zijlstra
  • J. Anim. Sci..2020 Jul;skaa224. doi: 10.1093/jas/skaa224.Epub 2020-07-16.

フコイダンを精製したフコイダンは、UVB誘発ヒト角化細胞において、光酸化ストレスと皮膚バリア障害を抑制する保護効果があることを示した

Fucoidan refined by Sargassum confusum indicate protective effects suppressing photo-oxidative stress and skin barrier perturbation in UVB-induced human keratinocytes.
  • Ilekuttige Priyan Shanura Fernando
  • Mawalle Kankanamge Hasitha Madhawa Dias
  • Disanayake Mudiyanselage Dinesh Madusanka
  • Eui Jeong Han
  • Min Ju Kim
  • You-Jin Jeon
  • Ginnae Ahn
  • Int. J. Biol. Macromol..2020 Jul;S0141-8130(20)33890-3. doi: 10.1016/j.ijbiomac.2020.07.136.Epub 2020-07-15.

グアノシンは軽度外傷性脳損傷後の行動およびミトコンドリアの生体エネルギー変化に対して保護する

Guanosine Protects Against Behavioural and Mitochondrial Bioenergetic Alterations after Mild Traumatic Brain Injury.
  • Aline Alves Courtes
  • Débora Farina Gonçalves
  • Diane Duarte Hartmann
  • Pamela Carvalho da Rosa
  • Gustavo Cassol
  • Luiz Fernando Freire Royes
  • Nelson Rodrigues de Carvalho
  • Félix Alexandre Antunes Soares
  • Brain Res. Bull..2020 Jul;S0361-9230(20)30550-5. doi: 10.1016/j.brainresbull.2020.07.003.Epub 2020-07-15.

いくつかの腫瘍由来の細胞株に対する葉エタノール抽出物およびイヌインターフェロンとの組み合わせの抗増殖活性

antiproliferation activity of leaves ethanol extract and its combination with canine interferons on several tumor-derived cell lines.
  • Bambang Pontjo Priosoeryanto
  • Riski Rostantinata
  • Eva Harlina
  • Waras Nurcholis
  • Rachmi Ridho
  • Lina Noviyanti Sutardi
  • Vet World.2020 May;13(5):931-939. Vetworld-13-931. doi: 10.14202/vetworld.2020.931-939.Epub 2020-05-19.

冠動脈疾患の中等度または高リスクの症候性患者に対するストレスダイナミック心筋CT灌流。絶対心筋血流解析と相対心筋血流解析の最適化と増分改善

Stress dynamic myocardial CT perfusion for symptomatic patients with intermediate- or high-risk of coronary artery disease: Optimization and incremental improvement between the absolute and relative myocardial blood flow analysis.
  • Yan Yi
  • Cheng Xu
  • Wei Wu
  • Yun Wang
  • Yu-Mei Li
  • Ying-Qian Ge
  • Zhu-Jun Shen
  • Jia-Yin Zhang
  • Bin Lu
  • Zheng-Yu Jin
  • Yi-Ning Wang
  • J Cardiovasc Comput Tomogr.2020 Jan;S1934-5925(19)30582-9. doi: 10.1016/j.jcct.2020.01.010.Epub 2020-01-30.

多発性硬化症患者におけるヒト免疫不全ウイルス感染症の獲得：これらの状態はお互いの経過にポジティブな影響を与える可能性があるか？

Acquisition of human immunodeficiency virus infection in a patient with multiple sclerosis: could these conditions positively influence each other's course?
  • Ilaria Mainardi
  • Maria Teresa Ferrò
  • Matteo Gastaldi
  • Diego Franciotta
  • Paola Cinque
  • J. Neurovirol..2020 Jul;10.1007/s13365-020-00876-7. doi: 10.1007/s13365-020-00876-7.Epub 2020-07-15.

BMPシグナル伝達経路の阻害は、実験的自己免疫性脳脊髄炎の確立した臨床症状を改善した

Inhibition of the BMP Signaling Pathway Ameliorated Established Clinical Symptoms of Experimental Autoimmune Encephalomyelitis.
  • Herena Eixarch
  • Laura Calvo-Barreiro
  • Carme Costa
  • Gemma Reverter-Vives
  • Mireia Castillo
  • Vanessa Gil
  • José Antonio Del Río
  • Xavier Montalban
  • Carmen Espejo
  • Neurotherapeutics.2020 Jul;10.1007/s13311-020-00885-8. doi: 10.1007/s13311-020-00885-8.Epub 2020-07-17.

地下水に生息するエルシマイクロビアは、腸内細菌群のエルシマイクロビアに比べて代謝的に多様であり、一部のエルシマイクロビアは新規なニトロゲナーゼの類縁体を持っている

Groundwater Elusimicrobia are metabolically diverse compared to gut microbiome Elusimicrobia and some have a novel nitrogenase paralog.
  • Raphaël Méheust
  • Cindy J Castelle
  • Paula B Matheus Carnevali
  • Ibrahim F Farag
  • Christine He
  • Lin-Xing Chen
  • Yuki Amano
  • Laura A Hug
  • Jillian F Banfield
  • ISME J.2020 Jul;10.1038/s41396-020-0716-1. doi: 10.1038/s41396-020-0716-1.Epub 2020-07-17.

シングルセルRNA-seqとバルクRNA-seqの統合解析により、腫瘍の不均一性に加えて、TNBCにおけるM2様の腫瘍関連マクロファージ浸潤と攻撃性が解明された

Integrated analysis of single-cell RNA-seq and bulk RNA-seq unravels tumour heterogeneity plus M2-like tumour-associated macrophage infiltration and aggressiveness in TNBC.
  • Xuanwen Bao
  • Run Shi
  • Tianyu Zhao
  • Yanfang Wang
  • Natasa Anastasov
  • Michael Rosemann
  • Weijia Fang
  • Cancer Immunol. Immunother..2020 Jul;10.1007/s00262-020-02669-7. doi: 10.1007/s00262-020-02669-7.Epub 2020-07-17.

大腸がんの治療反応予測バイオマーカーとしての遺伝子多型と関連INDEL-個別化医療に向けて

gene polymorphisms and related indel as predictor biomarkers of treatment response for colorectal cancer - toward a personalized medicine.
  • Mouadh Barbirou
  • Ikram Sghaier
  • Sinda Bedoui
  • Rahma Ben Abderrazek
  • Hazar Kraiem
  • Azer Farah
  • Rym Hassiki
  • Amina Mokrani
  • Amel Mezlini
  • Wassim Y Almawi
  • Besma Loueslati-Yacoubi
  • Balkiss Bouhaouala-Zahar
  • Tumour Biol..2020 Jun;42(6):1010428320925237. doi: 10.1177/1010428320925237.

薬剤耐性強迫性障害（OCD）における rTMS 治療の有効性と臨床的予測因子：レトロスペクティブ研究

Efficacy and clinical predictors of response to rTMS treatment in pharmacoresistant obsessive-compulsive disorder (OCD): a retrospective study.
  • Reza Rostami
  • Reza Kazemi
  • Arezoo Jabbari
  • Azam Sadat Madani
  • Hosseinreza Rostami
  • Mohammad Amin Taherpour
  • Parviz Molavi
  • Nematollah Jaafari
  • Min-Fang Kuo
  • Carmelo M Vicario
  • Michael A Nitsche
  • Mohammad Ali Salehinejad
  • BMC Psychiatry.2020 Jul;20(1):372. 10.1186/s12888-020-02769-9. doi: 10.1186/s12888-020-02769-9.Epub 2020-07-16.

特異性タンパク質1のフレームシフト変異が、家族性骨髄不全におけるSp1介在転写のスーパーアクチベーションを誘発することを明らかにした

A frameshift variant in specificity protein 1 triggers superactivation of Sp1-mediated transcription in familial bone marrow failure.
  • Hemanth Tummala
  • Amanda J Walne
  • Findlay Bewicke-Copley
  • Alicia Ellison
  • Nikolas Pontikos
  • Maria G Bridger
  • Ana Rio-Machin
  • Jasmin K Sidhu
  • Jun Wang
  • Henrik Hasle
  • Jude Fitzgibbon
  • Tom Vulliamy
  • Inderjeet Dokal
  • Proc. Natl. Acad. Sci. U.S.A..2020 Jul;202002857. doi: 10.1073/pnas.2002857117.Epub 2020-07-07.

高所得国における社会経済的グループ間の室内空気汚染への曝露。文献のスコープレビューとモデル化の方法論

Exposure to indoor air pollution across socio-economic groups in high-income countries: A scoping review of the literature and a modelling methodology.
  • Lauren Ferguson
  • Jonathon Taylor
  • Michael Davies
  • Clive Shrubsole
  • Phil Symonds
  • Sani Dimitroulopoulou
  • Environ Int.2020 Jul;143:105748. S0160-4120(19)34091-7. doi: 10.1016/j.envint.2020.105748.Epub 2020-07-03.

Brd1発現の低下は、可逆的なうつ病様行動と遺伝子発現の変化をもたらす

Reduced Brd1 expression leads to reversible depression-like behaviors and gene-expression changes in female mice.
  • Anto P Rajkumar
  • Per Qvist
  • Julie G Donskov
  • Ross Lazarus
  • Jonatan Pallesen
  • Nicoletta Nava
  • Gudrun Winther
  • Nico Liebenberg
  • Sanne H la Cour
  • Veerle Paternoster
  • Tue Fryland
  • Johan Palmfeldt
  • Kim Fejgin
  • Arne Mørk
  • Mette Nyegaard
  • Bente Pakkenberg
  • Michael Didriksen
  • Jens R Nyengaard
  • Gregers Wegener
  • Ole Mors
  • Jane H Christensen
  • Anders D Børglum
  • Transl Psychiatry.2020 Jul;10(1):239. 10.1038/s41398-020-00914-2. doi: 10.1038/s41398-020-00914-2.Epub 2020-07-17.

慢性腎臓病患者におけるクレアチニンとシスタチンCによる糸球体濾過率の不明確な傾向：KNOW-CKDコホートからの結果

Discrepant glomerular filtration rate trends from creatinine and cystatin C in patients with chronic kidney disease: results from the KNOW-CKD cohort.
  • Eunjeong Kang
  • Seung Seok Han
  • Jayoun Kim
  • Sue Kyung Park
  • Wookyung Chung
  • Yun Kyu Oh
  • Dong-Wan Chae
  • Yong-Soo Kim
  • Curie Ahn
  • Kook-Hwan Oh
  • BMC Nephrol.2020 Jul;21(1):280. 10.1186/s12882-020-01932-4. doi: 10.1186/s12882-020-01932-4.Epub 2020-07-16.

COVID-19 パンデミック時の表皮水疱症の集学的ケア-コンセンサス。国際的な専門家パネルによる勧告

Multidisciplinary Care of Epidermolysis Bullosa during the COVID-19 Pandemic - Consensus: Recommendations by an International Panel of Experts.
  • Dedee F Murrell
  • Anne W Lucky
  • Julio C Salas-Alanis
  • David T Woodley
  • Francis Palisson
  • Ken Natsuga
  • Milos Nikolic
  • Mae Ramirez-Quizon
  • Amy S Paller
  • Irene Lara-Corrales
  • Mohammadreza Amir Barzegar
  • Eli Sprecher
  • Cristina Has
  • Martin Laimer
  • Anna L Bruckner
  • Asli Bilgic
  • Arti Nanda
  • Diana Purvis
  • Alain Hovnanian
  • Slobodna Murat-Sušić
  • Johannes Bauer
  • Johannes S Kern
  • Christine Bodemer
  • Linda K Martin
  • Jemima Mellerio
  • Cezary Kowaleski
  • Susan J Robertson
  • Leena Bruckner-Tuderman
  • Elena Pope
  • M Peter Marinkovich
  • Jean Y Tang
  • John Su
  • Jouni Uitto
  • Lawrence F Eichenfield
  • Joyce Teng
  • Mark Jean Aan Koh
  • Sang Eun Lee
  • Phuong Khuu
  • Heather I Rishel
  • Mette Sommerlund
  • Karen Wiss
  • Chao-Kai Hsu
  • Tor Wo Chiu
  • Anna E Martinez
  • J. Am. Acad. Dermatol..2020 Jul;S0190-9622(20)32195-2. doi: 10.1016/j.jaad.2020.06.1023.Epub 2020-07-15.

カタツムリはTOR依存的にエンドサイクリングを同期させ、ショウジョウバエの臨界体重チェックポイントの間にエンドレプリーションの一時停止からの進入と脱出を調整している

Snail synchronizes endocycling in a TOR-dependent manner to coordinate entry and escape from endoreplication pausing during the Drosophila critical weight checkpoint.
  • Jie Zeng
  • Nhan Huynh
  • Brian Phelps
  • Kirst King-Jones
  • PLoS Biol..2020 02;18(2):e3000609. PBIOLOGY-D-19-00191. doi: 10.1371/journal.pbio.3000609.Epub 2020-02-25.

オーストラリアの入院患者の精神保健サービスにおける、攻撃性、自傷行為、性的危害、逃亡などの懸念行動の調査

Exploring behaviours of concern including aggression, self-harm, sexual harm and absconding within an Australian inpatient mental health service.
  • Matthew Kang
  • Hannah Bushell
  • Stuart Lee
  • Caitlin Berry
  • Yitzchak Hollander
  • Ilan Rauchberger
  • Fiona Whitecross
  • Australas Psychiatry.2020 Jun;:1039856220926940. doi: 10.1177/1039856220926940.Epub 2020-06-02.

殺虫性スズメバチ毒素Γ-ポンピリドトキシンは、電位依存性ナトリウムチャネルを調節する線形ペプチドである

The insecticidal wasp toxin Γ-Pompilidotoxin is a linear peptide modulating voltage-gated sodium channels.
  • Steve Peigneur
  • Andrey V Tsarev
  • Alexander S Paramonov
  • Christina I Schroeder
  • Maria P Ikonomopoulou
  • Hidetoshi Inagaki
  • David J Craik
  • Katsuhiro Konno
  • Zakhar O Shenkarev
  • Jan Tytgat
  • Toxicon.2020 Apr;177 Suppl 1:S40. S0041-0101(19)30831-1. doi: 10.1016/j.toxicon.2019.12.069.

カフェイン摂取が確認された早産児を持つ妊婦のコホートにおけるCYP2E1代謝活性の変調

Modulation of CYP2E1 metabolic activity in a cohort of confirmed caffeine ingesting pregnant women with preterm offspring.
  • M R Alcorta-García
  • C N López-Villaseñor
  • G Sánchez-Ferrer
  • H Flores-Mendoza
  • F Castorena-Torres
  • M A Aguilar-Torres
  • C M Sepúlveda-Treviño
  • J A Hernández-Hernández
  • R C López-Sánchez
  • V J Lara-Díaz
  • Mol Cell Pediatr.2020 Jun;7(1):4. 10.1186/s40348-020-00096-3. doi: 10.1186/s40348-020-00096-3.Epub 2020-06-01.

クラドリビンはATF4を介したアポトーシスを誘導し、びまん性大細胞型B細胞リンパ腫細胞においてSAHAと相乗的に作用します

Cladribine Induces ATF4 Mediated Apoptosis and Synergizes with SAHA in Diffuse Large B-Cell Lymphoma Cells.
  • Linyan Xu
  • Jun Jiao
  • Xiaoshen Sun
  • Wei Sang
  • Xiang Gao
  • Pu Yang
  • Dongmei Yan
  • Xuguang Song
  • Cai Sun
  • Mengdi Liu
  • Yuanyuan Qin
  • Yu Tian
  • Feng Zhu
  • Lingyu Zeng
  • Zhenyu Li
  • Kailin Xu
  • Int J Med Sci.2020;17(10):1375-1384. ijmsv17p1375. doi: 10.7150/ijms.41793.Epub 2020-05-30.

限界ヒト腎臓の生体外再生のための冷蔵保存による微小血管閉塞の溶解

Lysis of cold-storage-induced microvascular obstructions for ex vivo revitalization of marginal human kidneys.
  • Jenna R DiRito
  • Sarah A Hosgood
  • Melanie Reschke
  • Claire Albert
  • Laura G Bracaglia
  • John R Ferdinand
  • Benjamin J Stewart
  • Christopher M Edwards
  • Anand G Vaish
  • Sathia Thiru
  • David C Mulligan
  • Danielle J Haakinson
  • Menna R Clatworthy
  • W Mark Saltzman
  • Jordan S Pober
  • Michael L Nicholson
  • Gregory T Tietjen
  • Am. J. Transplant..2020 Jul;doi: 10.1111/ajt.16148.Epub 2020-07-05.

TBX5 R264KはT-box経路とは独立してマウスの拡張型心筋症発症の修飾因子として作用する

TBX5 R264K acts as a modifier to develop dilated cardiomyopathy in mice independently of T-box pathway.
  • Nariaki Miyao
  • Yukiko Hata
  • Hironori Izumi
  • Ryo Nagaoka
  • Yuko Oku
  • Ichiro Takasaki
  • Taisuke Ishikawa
  • Shinya Takarada
  • Mako Okabe
  • Hideyuki Nakaoka
  • Keijiro Ibuki
  • Sayaka Ozawa
  • Tomoyuki Yoshida
  • Hideyuki Hasegawa
  • Naomasa Makita
  • Naoki Nishida
  • Hisashi Mori
  • Fukiko Ichida
  • Keiichi Hirono
  • PLoS ONE.2020;15(4):e0227393. PONE-D-19-34630. doi: 10.1371/journal.pone.0227393.Epub 2020-04-01.

局所進行性肝胆道悪性腫瘍に対する複雑な肝切除術への肝移植経験の移行性-単施設での 3 10 年間の経験から得られた教訓

Transferability of Liver Transplantation Experience to Complex Liver Resection for Locally Advanced Hepatobiliary Malignancy - Lessons Learnt From 3 Decades of Single Center Experience.
  • Albert C Y Chan
  • Kenneth S H Chok
  • Jeff Dai
  • Simon H Y Tsang
  • Tan To Cheung
  • Ronnie Poon
  • S T Fan
  • C M Lo
  • Ann. Surg..2020 Jul;doi: 10.1097/SLA.0000000000004227.Epub 2020-07-09.

ヤコン（Smallanthus sonchifolius）は、大腸発癌の動物モデルにおいて、炎症、酸化ストレス、腸内変化を抑制しました

Yacón (Smallanthus sonchifolius) prevented inflammation, oxidative stress, and intestinal alterations in an animal model of colorectal carcinogenesis.
  • Thaísa Agrizzi Verediano
  • Mirelle Lomar Viana
  • Maria das Graças Vaz Tostes
  • Daniela Silva de Oliveira
  • Louisiane de Carvalho Nunes
  • Neuza Maria Brunoro Costa
  • J. Sci. Food Agric..2020 Jun;doi: 10.1002/jsfa.10595.Epub 2020-06-21.

カルシウムチャネル遮断剤としてのカルコン誘導体の同定と検討ファーマコフォアモデリング、ドッキング試験、インビトロスクリーニング、3D-QSAR解析

Identification and Investigation of Chalcone Derivatives as Calcium Channel Blockers: Pharmacophore modeling, Docking studies, In-vitro screening, and 3D-QSAR Analysis.
  • Amol S Sherikar
  • Manish S Bhatia
  • Rakesh P Dhavale
  • Curr Comput Aided Drug Des.2020 Jul;CAD-EPUB-108170. doi: 10.2174/1573409916666200714143930.Epub 2020-07-14.

γ9δ2T細胞の多様性と腫瘍細胞との受容体インターフェース

γ9δ2T cell diversity and the receptor interface with tumor cells.
  • Anna Vyborova
  • Dennis X Beringer
  • Domenico Fasci
  • Froso Karaiskaki
  • Eline van Diest
  • Lovro Kramer
  • Aram de Haas
  • Jasper Sanders
  • Anke Janssen
  • Trudy Straetemans
  • Daniel Olive
  • Jeanette Hw Leusen
  • Lola Boutin
  • Steven Nedellec
  • Samantha L Schwartz
  • Michael J Wester
  • Keith A Lidke
  • Emmanuel Scotet
  • Diane Lidke
  • Albert Jr Heck
  • Zsolt Sebestyen
  • Jurgen Kuball
  • J. Clin. Invest..2020 Jun;132489. doi: 10.1172/JCI132489.Epub 2020-06-02.

心不全患者に対するカルベジロール治療におけるβ，β，α-およびα-アドレナリン受容体に対する自己抗体検出の臨床的有用性

Clinical value of detecting autoantibodies against β-, β,- and α-adrenergic receptors in carvedilol treatment of patients with heart failure.
  • Dong-Yan Hou
  • Lin Xu
  • Zhi-Yong Zhang
  • Xiao-Rong Xu
  • Xin Wang
  • Juan Zhang
  • Jia-Mei Liu
  • Hua Wang
  • Jin Chen
  • Lin Zhang
  • J Geriatr Cardiol.2020 Jun;17(6):305-312. jgc-17-06-305. doi: 10.11909/j.issn.1671-5411.2020.06.002.

深海生物ノーザンシュリンプ（Pandalus borealis）と冷水サンゴ（Lophelia pertusa）の石油関連芳香族化合物、分散媒、アラスカノーススロープ原油に対する感受性

The sensitivity of the deepsea species northern shrimp (Pandalus borealis) and the cold-water coral (Lophelia pertusa) to oil-associated aromatic compounds, dispersant, and Alaskan North Slope crude oil.
  • Jenny Bytingsvik
  • Thomas F Parkerton
  • Julien Guyomarch
  • Luca Tassara
  • Stephane LeFloch
  • W Ray Arnold
  • Susanne M Brander
  • Aswani Volety
  • Lionel Camus
  • Mar. Pollut. Bull..2020 Jul;156:111202. S0025-326X(20)30320-9. doi: 10.1016/j.marpolbul.2020.111202.Epub 2020-05-17.

Flk2/Flt3を発現するCD34+CD38-単細胞から増殖させたクローン細胞による非肥満糖尿病/重症複合免疫不全マウスにおけるヒト造血の再構築

Reconstitution of human haematopoiesis in non-obese diabetic/severe combined immunodeficient mice by clonal cells expanded from single CD34+CD38- cells expressing Flk2/Flt3.
  • Yasuhiro Ebihara
  • Mika Wada
  • Takahiro Ueda
  • Ming-Jiang Xu
  • Atsushi Manabe
  • Ryuhei Tanaka
  • Mamoru Ito
  • Hideo Mugishima
  • Shigetaka Asano
  • Tatsutoshi Nakahata
  • Kohichiro Tsuji
  • Br. J. Haematol..2002 Nov;119(2):525-34. 3820. doi: 10.1046/j.1365-2141.2002.03820.x.

周辺環境への新興有機汚染物質の発生源としての埋立地浸出液のリスク評価と調査：中国済南市最大の埋立地のケーススタディ

Risk assessment and investigation of landfill leachate as a source of emerging organic contaminants to the surrounding environment: a case study of the largest landfill in Jinan City, China.
  • Kun Wang
  • Febelyn Reguyal
  • Tao Zhuang
  • Environ Sci Pollut Res Int.2020 Jul;10.1007/s11356-020-10093-8. doi: 10.1007/s11356-020-10093-8.Epub 2020-07-17.

ALG13 欠損症の 29 例の個体における優勢型および新規 de novo バリアント。臨床的記述、バイオマーカーの状態、生化学的分析と治療の提案

Predominant and novel de novo variants in 29 individuals with ALG13 deficiency: Clinical description, biomarker status, biochemical analysis and treatment suggestions.
  • Bobby G Ng
  • Erik A Eklund
  • Sergey A Shiryaev
  • Yin Y Dong
  • Mary-Alice Abbott
  • Carla Asteggiano
  • Michael J Bamshad
  • Eileen Barr
  • Jonathan A Bernstein
  • Shabeed Chelakkadan
  • John Christodoulou
  • Wendy K Chung
  • Michael A Ciliberto
  • Janice Cousin
  • Fiona Gardiner
  • Suman Ghosh
  • William D Graf
  • Stephanie Grunewald
  • Katherine Hammond
  • Natalie S Hauser
  • George E Hoganson
  • Kimberly M Houck
  • Jennefer N Kohler
  • Eva Morava
  • Austin A Larson
  • Pengfei Liu
  • Sujana Madathil
  • Colleen McCormack
  • Naomi J L Meeks
  • Rebecca Miller
  • Kristin G Monaghan
  • Deborah A Nickerson
  • Timothy Blake Palculict
  • Gabriela Magali Papazoglu
  • Beth A Pletcher
  • Ingrid E Scheffer
  • Andrea Beatriz Schenone
  • Rhonda E Schnur
  • Yue Si
  • Leah J Rowe
  • Alvaro H Serrano Russi
  • Rossana Sanchez Russo
  • Farouq Thabet
  • Allysa Tuite
  • María Mercedes Villanueva
  • Raymond Y Wang
  • Richard I Webster
  • Dorcas Wilson
  • Alice Zalan
  • Undiagnosed Diseases Network
  • Lynne A Wolfe
  • Jill A Rosenfeld
  • Lindsay Rhodes
  • Hudson H Freeze
  • J. Inherit. Metab. Dis..2020 Jul;doi: 10.1002/jimd.12290.Epub 2020-07-18.

1,2-ジメチルヒドラジンに対する肝臓および結腸の亜急性反応に関連する初期の分子イベント。肝臓と大腸の亜急性反応に関連する初期の分子イベント：前腫瘍性病変および新腫瘍性病変の発生に関する潜在的な意味合い

Early molecular events associated with liver and colon sub-acute responses to 1,2-dimethylhydrazine: Potential implications on preneoplastic and neoplastic lesion development.
  • Brunno Felipe Ramos Caetano
  • Mariana Baptista Tablas
  • Guilherme Ribeiro Romualdo
  • Maria Aparecida Marchesan Rodrigues
  • Luís Fernando Barbisan
  • Toxicol. Lett..2020 Sep;329:67-79. S0378-4274(20)30114-4. doi: 10.1016/j.toxlet.2020.04.009.Epub 2020-05-06.

カルバクロールの降圧効果は、ドラッグデリバリーシステムとしてβ-シクロデキストリンに組み込むことで改善される

Antihypertensive effect of carvacrol is improved after incorporation in β-cyclodextrin as a drug delivery system.
  • Liliane Barreto
  • Samuel Barbosa Camargo
  • Raiana Dos Anjos Moraes
  • Carla Fiama Medeiros
  • Anderson de Melo Jesus
  • Afrânio Evangelista
  • Cristiane Flora Villarreal
  • Lucindo José Quintans-Júnior
  • Darízy Flávia Silva
  • Clin. Exp. Pharmacol. Physiol..2020 Jun;doi: 10.1111/1440-1681.13364.Epub 2020-06-22.

メロン/ワタアブラムシ（Aphis gossypii Glover）のジノテフランに対する代謝抵抗性には、CYP6CY14、CYP6CY22、CYP6UN1の3つのチトクロームP450遺伝子の過剰発現が関与していることが明らかになった

The overexpression of three cytochrome P450 genes CYP6CY14, CYP6CY22 and CYP6UN1 contributed to metabolic resistance to dinotefuran in melon/cotton aphid, Aphis gossypii Glover.
  • Anqi Chen
  • Huihui Zhang
  • Tisheng Shan
  • Xueyan Shi
  • Xiwu Gao
  • Pestic Biochem Physiol.2020 Jul;167:104601. S0048-3575(20)30096-1. doi: 10.1016/j.pestbp.2020.104601.Epub 2020-05-11.

大気中のCs・I/Cs観測データと大気輸送・沈着モデルのマルチアンサンブルに基づく福島原発事故による初期I吸入線量の再評価

Reassessment of early I inhalation doses by the Fukushima nuclear accident based on atmospheric Cs and I/Cs observation data and multi-ensemble of atmospheric transport and deposition models.
  • Mai Takagi
  • Toshimasa Ohara
  • Daisuke Goto
  • Yu Morino
  • Junya Uchida
  • Tsuyoshi Thomas Sekiyama
  • Shoji F Nakayama
  • Mitsuru Ebihara
  • Yasuji Oura
  • Teruyuki Nakajima
  • Haruo Tsuruta
  • Yuichi Moriguchi
  • J Environ Radioact.2020 Jul;218:106233. S0265-931X(19)30992-0. doi: 10.1016/j.jenvrad.2020.106233.Epub 2020-03-17.

疫学における多様性、包摂性、代表性、参加性を向上させるための機会が豊富に存在する。現在のアプローチでは不十分なので、より多くの情報に基づいた行動が必要である

A Smorgasbord of Opportunities Exist to Improve Diversity, Inclusion, Representation, and Participation in Epidemiology: More Informed Action is Necessary Since Current Approaches are Insufficient.
  • Chandra L Jackson
  • Am. J. Epidemiol..2020 Jun;kwaa104. doi: 10.1093/aje/kwaa104.Epub 2020-06-30.

焼失性口内症候群患者884人における貧血、血行不良、高ホモシステイン血症、および血清胃頭頂細胞抗体陽性

Anemia, hematinic deficiencies, hyperhomocysteinemia, and serum gastric parietal cell antibody positivity in 884 patients with burning mouth syndrome.
  • Chun-Pin Chiang
  • Yu-Hsueh Wu
  • Yang-Che Wu
  • Julia Yu-Fong Chang
  • Yi-Ping Wang
  • Andy Sun
  • J. Formos. Med. Assoc..2020 Apr;119(4):813-820. S0929-6646(19)30882-4. doi: 10.1016/j.jfma.2019.10.013.Epub 2019-11-01.

アルツハイマー病による進行性認知症症候群：55例の解説と他の表現型との比較

Progressive dysexecutive syndrome due to Alzheimer's disease: a description of 55 cases and comparison to other phenotypes.
  • Ryan A Townley
  • Jonathan Graff-Radford
  • William G Mantyh
  • Hugo Botha
  • Angelina J Polsinelli
  • Scott A Przybelski
  • Mary M Machulda
  • Ahmed T Makhlouf
  • Matthew L Senjem
  • Melissa E Murray
  • Ross R Reichard
  • Rodolfo Savica
  • Bradley F Boeve
  • Daniel A Drubach
  • Keith A Josephs
  • David S Knopman
  • Val J Lowe
  • Clifford R Jack
  • Ronald C Petersen
  • David T Jones
  • Brain Commun.2020;2(1):fcaa068. fcaa068. doi: 10.1093/braincomms/fcaa068.Epub 2020-05-27.

軸性腰痛を有する被験者における腰部硬膜外ステロイド注射に対する反応とタンパク質および遺伝子バイオマーカーとの関連

Association of Protein and Genetic Biomarkers with Response to Lumbar Epidural Steroid Injections in Subjects with Axial Low Back Pain.
  • Stephen Schaaf
  • Wan Huang
  • Subashan Perera
  • Yvette Conley
  • Inna Belfer
  • Prakash Jayabalan
  • Katie Tremont
  • Paulo Coelho
  • Sara Ernst
  • Megan Cortazzo
  • Debra Weiner
  • Nam Vo
  • James Kang
  • Gwendolyn Sowa
  • Am J Phys Med Rehabil.2020 Jun;doi: 10.1097/PHM.0000000000001514.Epub 2020-06-22.

乳がん治療薬として最適化されたポリエチレングリコール化ポリマー-脂質ハイブリッドナノ粒子

Optimized Polyethylene Glycolylated Polymer-Lipid Hybrid Nanoparticles as a Potential Breast Cancer Treatment.
  • Salam Massadeh
  • Mustafa E Omer
  • Asmaa Alterawi
  • Rizwan Ali
  • Fayez H Alanazi
  • Fares Almutairi
  • Wejdan Almotairi
  • Faris F Alobaidi
  • Khulud Alhelal
  • Mansour S Almutairi
  • Abdulaziz Almalik
  • Aiman A Obaidat
  • Manal Alaamery
  • Alaa Eldeen Yassin
  • Pharmaceutics.2020 Jul;12(7). E666. doi: 10.3390/pharmaceutics12070666.Epub 2020-07-15.

再建血管性高血圧症2K1Cのラットで自発的な運動を行った場合、筋細胞内シグナル伝達の調整によりフィットネスが改善される

Fitness is improved by adjustments in muscle intracellular signaling in rats with renovascular hypertension 2K1C undergoing voluntary physical exercise.
  • Taynara Carolina Lima
  • Maria Andrea Barbosa
  • Daniela Caldeira Costa
  • Lenice Kappes Becker
  • Leonardo Máximo Cardoso
  • Andréia Carvalho Alzamora
  • Life Sci..2020 Jun;250:117549. S0024-3205(20)30297-6. doi: 10.1016/j.lfs.2020.117549.Epub 2020-03-13.

耐熱性または高温に敏感なダイズ遺伝子型の子葉系乳腺細胞における種子タンパク質組成とタンパク質貯蔵液胞 の構造に及ぼす熱ストレスの影響

Effect of Heat Stress on Seed Protein Composition and Ultrastructure of Protein Storage Vacuoles in the Cotyledonary Parenchyma Cells of Soybean Genotypes That Are Either Tolerant or Sensitive to Elevated Temperatures.
  • Hari B Krishnan
  • Won-Seok Kim
  • Nathan W Oehrle
  • James R Smith
  • Jason D Gillman
  • Int J Mol Sci.2020 Jul;21(13). E4775. doi: 10.3390/ijms21134775.Epub 2020-07-05.

モザンビークの薬剤耐性ホットスポットにおけるトリパノソーマ症の伝播におけるタバン科とグロッシン科の相対的役割の評価

Evaluation of the relative roles of the Tabanidae and Glossinidae in the transmission of trypanosomosis in drug resistance hotspots in Mozambique.
  • Fernando C Mulandane
  • Louwtjie P Snyman
  • Denise R A Brito
  • Jeremy Bouyer
  • José Fafetine
  • Jan Van Den Abbeele
  • Marinda Oosthuizen
  • Vincent Delespaux
  • Luis Neves
  • Parasit Vectors.2020 Apr;13(1):219. 10.1186/s13071-020-04087-1. doi: 10.1186/s13071-020-04087-1.Epub 2020-04-29.

精神保健および救急サービスにおける看護師との相互作用に関する自殺願望と行動を持つ成人の視点。システマティックレビュー

The perspectives of adults with suicidal ideation and behaviour regarding their interactions with nurses in mental health and emergency services: A systematic review.
  • Joeri Vandewalle
  • Liesbet Van Bos
  • Peter Goossens
  • Dimitri Beeckman
  • Ann Van Hecke
  • Eddy Deproost
  • Sofie Verhaeghe
  • Int J Nurs Stud.2020 Jun;110:103692. S0020-7489(20)30176-0. doi: 10.1016/j.ijnurstu.2020.103692.Epub 2020-06-20.

SARS-CoV-2のNsp1タンパク質によるトランスレーショナルシャットダウンと免疫回避の構造的基盤

Structural basis for translational shutdown and immune evasion by the Nsp1 protein of SARS-CoV-2.
  • Matthias Thoms
  • Robert Buschauer
  • Michael Ameismeier
  • Lennart Koepke
  • Timo Denk
  • Maximilian Hirschenberger
  • Hanna Kratzat
  • Manuel Hayn
  • Timur Mackens-Kiani
  • Jingdong Cheng
  • Jan H Straub
  • Christina M Stürzel
  • Thomas Fröhlich
  • Otto Berninghausen
  • Thomas Becker
  • Frank Kirchhoff
  • Konstantin M J Sparrer
  • Roland Beckmann
  • Science.2020 Jul;eabc8665. doi: 10.1126/science.abc8665.Epub 2020-07-17.

ジヒドロピリジンカルシウムチャネルブロッカーの皮質および小脳の有機リン酸塩による酸化的損傷に対する治療効果：インビボ試験

Therapeutic Potential of Dihydropyridine Calcium Channel Blockers on Oxidative Injury Caused by Organophosphates in Cortex and Cerebellum: An In Vivo Study.
  • Sara Ataei
  • Susan Abaspanah
  • Rasool Haddadi
  • Mojdeh Mohammadi
  • Amir Nili-Ahmadabadi
  • Indian J Clin Biochem.2020 Jul;35(3):339-346. 830. doi: 10.1007/s12291-019-00830-3.Epub 2019-05-14.

標準的な臨床試験の適格性を満たさない新たに診断された高悪性度の骨髄新生物患者の生存率

Survival of patients with newly diagnosed high-grade myeloid neoplasms who do not meet standard trial eligibility.
  • Mary-Elizabeth M Percival
  • Megan Othus
  • Sarah Mirahsani
  • Kelda M Gardner
  • Carole Shaw
  • Anna B Halpern
  • Pamela S Becker
  • Paul C Hendrie
  • Mohamed L Sorror
  • Roland B Walter
  • Elihu H Estey
  • Haematologica.2020 Jul;haematol.2020.254938. doi: 10.3324/haematol.2020.254938.Epub 2020-07-09.

妊娠中のヘルミン症感染症がガボンの乳児におけるワクチン免疫原性に及ぼす影響

Impact of Helminth Infections during Pregnancy on Vaccine Immunogenicity in Gabonese Infants.
  • Judith Flügge
  • Ayôla Akim Adegnika
  • Yabo Josiane Honkpehedji
  • Thaisa L Sandri
  • Esther Askani
  • Gédéon Prince Manouana
  • Marguerite Massinga Loembe
  • Sina Brückner
  • Mohamed Duali
  • Johannes Strunk
  • Benjamin Mordmüller
  • Selidji Todagbe Agnandji
  • Bertrand Lell
  • Peter G Kremsner
  • Meral Esen
  • Vaccines (Basel).2020 Jul;8(3). E381. doi: 10.3390/vaccines8030381.Epub 2020-07-11.

牛における非生きた炭疽菌ワクチン候補の免疫原性と、Sterne生きた胞子ワクチンと比較したA/Jマウスモデルにおける免疫血清の保護効果

Immunogenicity of Non-Living Anthrax Vaccine Candidates in Cattle and Protective Efficacy of Immune Sera in A/J Mouse Model Compared to the Sterne Live Spore Vaccine.
  • Solomon Jauro
  • Okechukwu C Ndumnego
  • Charlotte Ellis
  • Angela Buys
  • Wolfgang Beyer
  • Henriette van Heerden
  • Pathogens.2020 Jul;9(7). E557. doi: 10.3390/pathogens9070557.Epub 2020-07-10.

非ヒスパニック黒人および白人の正常血圧および高血圧症前の感覚神経介在性および一酸化窒素依存性の皮膚血管拡張

Sensory nerve-mediated and nitric oxide-dependent cutaneous vasodilation in normotensive and prehypertensive non-Hispanic blacks and whites.
  • Brett J Wong
  • Casey G Turner
  • James T Miller
  • Demetria C Walker
  • Yesser Sebeh
  • Matthew J Hayat
  • Jeffrey S Otis
  • Arshed A Quyyumi
  • Am. J. Physiol. Heart Circ. Physiol..2020 Aug;319(2):H271-H281. doi: 10.1152/ajpheart.00177.2020.Epub 2020-06-19.

論文「経皮的冠動脈インターベンションを受けた急性冠症候群患者における出血イベントの予測に対するPRECISE-DAPTスコアの臨床的有用性。SMART-DATE無作為化試験からの分析」と題する論文が発表されました

Response by Choi et al to Letter Regarding Article, "Clinical Usefulness of PRECISE-DAPT Score for Predicting Bleeding Events in Patients With Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention: An Analysis From the SMART-DATE Randomized Trial".
  • Ki Hong Choi
  • Young Bin Song
  • Joo-Yong Hahn
  • Circ Cardiovasc Interv.2020 Jul;13(7):e009645. doi: 10.1161/CIRCINTERVENTIONS.120.009645.Epub 2020-07-17.

5種類の高密度材料の体積寸法に及ぼす窓と金属アーチファクト低減アルゴリズムの影響：コーンビームCTによる研究

Influence of windowing and metal artefact reduction algorithms on the volumetric dimensions of five different high-density materials: a cone-beam CT study.
  • Fernanda Coelho-Silva
  • Luciano Augusto Cano Martins
  • Daniela Azeredo Braga
  • Eliana Zandonade
  • Francisco Haiter-Neto
  • Sergio Lins de-Azevedo-Vaz
  • Dentomaxillofac Radiol.2020 Jun;:20200039. doi: 10.1259/dmfr.20200039.Epub 2020-06-25.

ヒト上皮成長因子受容体2/4阻害剤投与後のトキソプラズマ・ゴンドイに感染した宿主細胞のシークレットーム解析

Secretome Analysis of Host Cells Infected with Toxoplasma gondii after Treatment of Human Epidermal Growth Factor Receptor 2/4 Inhibitors.
  • Hye-Jung Kim
  • Hye-Jin Ahn
  • Hyeweon Kang
  • Jaehui Park
  • Seul Gi Oh
  • Saehae Choi
  • Won-Kyu Lee
  • Ho-Woo Nam
  • Korean J. Parasitol..2020 Jun;58(3):249-255. kjp.2020.58.3.249. doi: 10.3347/kjp.2020.58.3.249.Epub 2020-06-26.

グルタチオンSトランスフェラーゼA1遺伝子多型（-69C>T、rs3957356）がシクロホスファミド静注薬の有効性および副作用に及ぼす影響：エジプトのループス腎炎患者を対象としたケースコントロール研究

Influence of glutathione S transferase A1 gene polymorphism (-69C > T, rs3957356) on intravenous cyclophosphamide efficacy and side effects: a case-control study in Egyptian patients with lupus nephritis.
  • Doaa H S Attia
  • Mervat Eissa
  • Lamees A Samy
  • Rasha A Khattab
  • Clin. Rheumatol..2020 Jul;10.1007/s10067-020-05276-0. doi: 10.1007/s10067-020-05276-0.Epub 2020-07-13.

WSe光導波路におけるフェムト秒励起子ダイナミクス

Femtosecond exciton dynamics in WSe optical waveguides.
  • Aaron J Sternbach
  • Simone Latini
  • Sanghoon Chae
  • Hannes Hübener
  • Umberto De Giovannini
  • Yinming Shao
  • Lin Xiong
  • Zhiyuan Sun
  • Norman Shi
  • Peter Kissin
  • Guang-Xin Ni
  • Daniel Rhodes
  • Brian Kim
  • Nanfang Yu
  • Andrew J Millis
  • Michael M Fogler
  • Peter J Schuck
  • Michal Lipson
  • X-Y Zhu
  • James Hone
  • Richard D Averitt
  • Angel Rubio
  • D N Basov
  • Nat Commun.2020 Jul;11(1):3567. 10.1038/s41467-020-17335-w. doi: 10.1038/s41467-020-17335-w.Epub 2020-07-16.

社会的孤立ストレスによる神経炎症における非常に小さな胚性幹細胞の役割の可能性。新しいパラダイムの導入

The Potential Role of Very Small Embryonic-Like Stem Cells in the Neuroinflammation Induced by Social Isolation Stress: Introduction of a New Paradigm.
  • Arvin Haj-Mirzaian
  • Ayda Khosravi
  • Arya Haj-Mirzaian
  • Alireza Rahbar
  • Kiana Ramezanzadeh
  • Rajan Nikbakhsh
  • Fardad Pirri
  • Bhenam Talari
  • Maria Ghesmati
  • Rambod Nikbakhsh
  • Ahmad Reza Dehpour
  • Brain Res. Bull..2020 Jul;S0361-9230(20)30553-0. doi: 10.1016/j.brainresbull.2020.07.006.Epub 2020-07-15.

大豆油精製のための新しいレシチン:コレステロールアシル転移酵素は、よりクリーンなプロセスでより高い収量と余分な栄養価を提供します

A novel lecithin:cholesterol acyltransferase for soybean oil refining provides higher yields and extra nutritional value with a cleaner process.
  • Guillermo Hails
  • Sebastián Cerminati
  • Luciana Paoletti
  • Rodolfo Cabrera
  • Salvador Peirú
  • Andrés Aguirre
  • María E Castelli
  • Hugo G Menzella
  • Appl. Microbiol. Biotechnol..2020 Jul;10.1007/s00253-020-10786-7. doi: 10.1007/s00253-020-10786-7.Epub 2020-07-17.

オンラインHPLC-DPPHアッセイによる親水性相互作用クロマトグラフィーを用いたFloccularia luteovirensからの高極性フリーラジカル阻害剤の調製

Preparative isolation of highly polar free radical inhibitor from Floccularia luteovirens using hydrophilic interaction chromatography directed by on-line HPLC-DPPH assay.
  • Jun Dang
  • Chengbiao Chen
  • Jianbin Ma
  • YangZom Dawa
  • Qi Wang
  • Yanduo Tao
  • Qilan Wang
  • Tengfei Ji
  • J. Chromatogr. B Analyt. Technol. Biomed. Life Sci..2020 Apr;1142:122043. S1570-0232(19)31863-X. doi: 10.1016/j.jchromb.2020.122043.Epub 2020-02-26.

非治癒的内視鏡的切除後の早期胃癌患者におけるリンパ節転移および残存腫瘍の予測因子：システマティックレビューおよびメタアナリシス

Predictors of lymph node metastasis and residual tumor in early gastric cancer patients after noncurative endoscopic resection: a systematic review and meta-analysis.
  • Bolun Jiang
  • Li Zhou
  • Jun Lu
  • Yizhi Wang
  • Junchao Guo
  • Therap Adv Gastroenterol.2020;13:1756284820935033. 10.1177_1756284820935033. doi: 10.1177/1756284820935033.Epub 2020-06-23.

潜在的な創傷治癒アプリケーションのための抗酸化特性を有するアルギン酸塩/ヒトエラスチン様ポリペプチド複合フィルム

Alginate/human elastin-like polypeptide composite films with antioxidant properties for potential wound healing application.
  • Carlo Bergonzi
  • Giovanna Gomez d'Ayala
  • Lisa Elviri
  • Paola Laurienzo
  • Antonella Bandiera
  • Ovidio Catanzano
  • Int. J. Biol. Macromol..2020 Jul;S0141-8130(20)33838-1. doi: 10.1016/j.ijbiomac.2020.07.084.Epub 2020-07-14.

生分解性マイクロスフィアにカプセル化されたイエシニア・ペスティスF1およびVサブユニットワクチンを用いた気管支肺および筋肉内免疫後の保護研究：有効性の比較

Protection studies following bronchopulmonary and intramuscular immunisation with yersinia pestis F1 and V subunit vaccines coencapsulated in biodegradable microspheres: a comparison of efficacy.
  • J E Eyles
  • E D Williamson
  • I D Spiers
  • H O Alpar
  • Vaccine.2000 Aug;18(28):3266-71. S0264-410X(00)00128-6. doi: 10.1016/s0264-410x(00)00128-6.

Herbst）のCYP450モノオキシゲナーゼの分子ドッキング解析により、ケルセチンとパラオキソンおよびテトラエチルピロリン酸との相乗効果が明らかになった

Molecular docking analyses of CYP450 monooxygenases of (Herbst) reveal synergism of quercetin with paraoxon and tetraethyl pyrophosphate: studies.
  • Ammarah Ghaffar
  • Sheikh Arslan Sehgal
  • Rida Fatima
  • Roya Batool
  • Ume Aimen
  • Sliha Awan
  • Sajida Batool
  • Faheem Ahmad
  • Syed M Nurulain
  • Toxicol Res (Camb).2020 Jun;9(3):212-221. tfaa023. doi: 10.1093/toxres/tfaa023.Epub 2020-05-09.

転移性膵臓がん患者を対象とした Veliparib（ABT-888）と 5-フルオロウラシルおよびオキサリプラチンの併用療法の第 I/II 相試験

A Phase I/II Study of Veliparib (ABT-888) in combination with 5-Fluorouracil and Oxaliplatin in Patients with Metastatic Pancreatic Cancer.
  • Michael J Pishvaian
  • Hongkun Wang
  • Aiwu Ruth He
  • Jimmy J Hwang
  • Brandon G Smaglo
  • Sunnie S Kim
  • Benjamin A Weinberg
  • Louis M Weiner
  • John L Marshall
  • Jonathan R Brody
  • Clin. Cancer Res..2020 Jul;clincanres.1301.2020. doi: 10.1158/1078-0432.CCR-20-1301.Epub 2020-07-15.

アセトニトリルからのビニレン結合型共有結合有機フレームワークの合成（東工大院理工）．シクロ三量化反応とアルドール縮合反応をワンポットで組み合わせる

Synthesis of Vinylene-Linked Covalent Organic Frameworks from Acetonitrile: Combining Cyclotrimerization and Aldol Condensation in One Pot.
  • Amitava Acharjya
  • Lewis Longworth-Dunbar
  • Jerome Roeser
  • Pradip Pachfule
  • Arne Thomas
  • J. Am. Chem. Soc..2020 Jul;doi: 10.1021/jacs.0c04570.Epub 2020-07-17.

神経活性ステロイドのアルファキサロンとCDNC24は効果的な催眠剤であり、GABA電流の増強剤ですが、発育途上のラットの脳には神経毒性はありません

Neuroactive steroids alphaxalone and CDNC24 are effective hypnotics and potentiators of GABA currents, but are not neurotoxic to the developing rat brain.
  • Vesna Tesic
  • Srdjan M Joksimovic
  • Nidia Quillinan
  • Kathiresan Krishnan
  • Douglas F Covey
  • Slobodan M Todorovic
  • Vesna Jevtovic-Todorovic
  • Br J Anaesth.2020 05;124(5):603-613. S0007-0912(20)30060-X. doi: 10.1016/j.bja.2020.01.013.Epub 2020-03-06.

自己ナノ乳化システムを用いた小児用抗てんかん薬スティリペントールの経口バイオアベイラビリティの改善。処方と薬物動態の研究

Using Self-Nanoemulsifying System to Improve Oral Bioavailability of a Pediatric Antiepileptic Agent Stiripentol: Formulation and Pharmacokinetics Studies.
  • Qiuyang Dai
  • Peiyan Zhang
  • Yilan Jin
  • Mi Tang
  • Mengling Shen
  • Shujun Xu
  • Susu Huang
  • Yong Chen
  • AAPS PharmSciTech.2020 Jul;21(5):192. 10.1208/s12249-020-01730-z. doi: 10.1208/s12249-020-01730-z.Epub 2020-07-13.

HIV陽性患者を対象としたウイルス抑制下での600mgエファビレンツ、テノフォビルジソプロキシルフマル酸塩、エムトリシタビンから400mgエファビレンツ、テノフォビルジソプロキシルフマル酸塩、ラミブジンへの切り替えに関する治療薬モニタリング試験

Therapeutic drug monitoring study on the switch from coformulated 600-mg efavirenz, tenofovir disoproxil fumarate, and emtricitabine to coformulated 400-mg efavirenz, tenofovir disoproxil fumarate, and lamivudine among HIV-positive patients with viral suppression.
  • Wei-Chieh Huang
  • Chun-Kai Huang
  • Sung-Hsi Huang
  • Shu-Wen Lin
  • Shyh-Tyan Ou
  • Yi-Ting Chen
  • Ya-Wen Chen
  • Shu-Yuan Chang
  • Wen-Chun Liu
  • Hsin-Yun Sun
  • Chien-Ching Hung
  • J Microbiol Immunol Infect.2020 Jul;S1684-1182(20)30151-1. doi: 10.1016/j.jmii.2020.06.010.Epub 2020-07-07.

HIV と好酸球性食道炎の患者におけるアバカビル、エムトリシタビン、および砕いたドルテグラビルとテノフォビル・アラフェナミドによる持続的なウイルス学的抑制

Sustained virologic suppression with abacavir, emtricitabine, and crushed dolutegravir and tenofovir alafenamide in a patient with HIV and eosinophilic esophagitis.
  • Sarah E Moore
  • Emily Huesgen
  • Zachary Howe
  • Int J STD AIDS.2020 03;31(3):285-287. doi: 10.1177/0956462419895690.Epub 2020-02-09.

液体シンチレーション検出を利用した生物学的および病院廃棄物サンプルからのI評価のための高速応答フローベースの方法

Fast-response flow-based method for evaluating I from biological and hospital waste samples exploiting liquid scintillation detection.
  • Donagi Esparza
  • Manuel Valiente
  • Antoni Borràs
  • Marina Villar
  • Luz O Leal
  • Fernando Vega
  • Víctor Cerdà
  • Laura Ferrer
  • Talanta.2020 Jan;206:120224. S0039-9140(19)30857-4. doi: 10.1016/j.talanta.2019.120224.Epub 2019-08-05.

マンガンはプロテアソーム20Sおよびヒートショック蛋白質90および70の変化を介してAβおよびタウ蛋白質レベルを増加させ、単回および反復処理後のSN56コリン作動性細胞死を誘導する

Manganese increases Aβ and Tau protein levels through proteasome 20S and heat shock proteins 90 and 70 alteration, leading to SN56 cholinergic cell death following single and repeated treatment.
  • Paula Moyano
  • José Manuel García
  • Jimena García
  • María José Anadon
  • María Victoria Naval
  • María Teresa Frejo
  • Emma Sola
  • Adela Pelayo
  • Javier Del Pino
  • Ecotoxicol. Environ. Saf..2020 Jul;203:110975. S0147-6513(20)30814-9. doi: 10.1016/j.ecoenv.2020.110975.Epub 2020-07-14.

血液透析患者のための持続的運動プログラム。ポルトガル、カナダ、メキシコ、ドイツにおける成功したアプローチの特徴

Sustained exercise programs for hemodialysis patients: The characteristics of successful approaches in Portugal, Canada, Mexico, and Germany.
  • João L Viana
  • Pedro Martins
  • Kristen Parker
  • Magdalena Madero
  • Héctor Pérez Grovas
  • Kirsten Anding
  • Stefan Degenhardt
  • Iwona Gabrys
  • Shauna Raugust
  • Christina West
  • Theresa E Cowan
  • Kenneth R Wilund
  • Semin Dial.2019 07;32(4):320-330. doi: 10.1111/sdi.12814.Epub 2019-05-13.

鉄分を多く含む土壌と粘土を多く含む土壌の選択：ウガンダのブドンゴ森林保護区における白黒コロブスザルを用いたジオハジーフィールド実験

Selecting between iron-rich and clay-rich soils: a geophagy field experiment with black-and-white colobus monkeys in the Budongo Forest Reserve, Uganda.
  • Paula A Pebsworth
  • Thibaud Gruber
  • Joshua D Miller
  • Klaus Zuberbühler
  • Sera L Young
  • Primates.2020 Jul;10.1007/s10329-020-00845-y. doi: 10.1007/s10329-020-00845-y.Epub 2020-07-16.

メトホルミンの治療用量は，子癇前症，IUGRおよび健康な妊娠からの血清の存在下では，血管新生に影響を与えない

Therapeutic doses of metformin do not have impact on angiogenesis in presence of sera from pre-eclamptic, IUGR and healthy pregnancies.
  • Anita Virtanen
  • Outi Huttala
  • Kati Tihtonen
  • Tarja Toimela
  • Tuula Heinonen
  • Hannele Laivuori
  • Jukka Uotila
  • Pregnancy Hypertens.2020 Jul;22:7-13. S2210-7789(20)30089-1. doi: 10.1016/j.preghy.2020.06.008.Epub 2020-07-06.

ハイチにおけるリンパ系フィラリア症に対するジエチルカルバマジン、アルベンダゾール、およびイベルメクチンの大量投与時の安全性と有効性。2群共同、非盲検、クラスターランダム化、コミュニティ試験の結果

Safety and efficacy of co-administered diethylcarbamazine, albendazole and ivermectin during mass drug administration for lymphatic filariasis in Haiti: Results from a two-armed, open-label, cluster-randomized, community study.
  • Christine L Dubray
  • Anita D Sircar
  • Valery Madsen Beau de Rochars
  • Joshua Bogus
  • Abdel N Direny
  • Jean Romuald Ernest
  • Carl R Fayette
  • Charles W Goss
  • Marisa Hast
  • Kobie O'Brian
  • Guy Emmanuel Pavilus
  • Daniel Frantz Sabin
  • Ryan E Wiegand
  • Gary J Weil
  • Jean Frantz Lemoine
  • PLoS Negl Trop Dis.2020 Jun;14(6):e0008298. PNTD-D-20-00067. doi: 10.1371/journal.pntd.0008298.Epub 2020-06-08.

イタリア・ヴァルカモニカ地域のコロナウイルス疾患による死亡の研究室予測因子2019（COVID-19）

Laboratory predictors of death from coronavirus disease 2019 (COVID-19) in the area of Valcamonica, Italy.
  • Graziella Bonetti
  • Filippo Manelli
  • Andrea Patroni
  • Alessandra Bettinardi
  • Gianluca Borrelli
  • Gianfranco Fiordalisi
  • Antonio Marino
  • Annamaria Menolfi
  • Sara Saggini
  • Roberta Volpi
  • Adriano Anesi
  • Giuseppe Lippi
  • Clin. Chem. Lab. Med..2020 06;58(7):1100-1105. /j/cclm.2020.58.issue-7/cclm-2020-0459/cclm-2020-0459.xml. doi: 10.1515/cclm-2020-0459.

トウモロコシにおける生物学的窒素固定根に関連したジアゾトロフにおける窒素酵素の発現の最適化

Biological Nitrogen Fixation in Maize: Optimizing Nitrogenase Expression in a Root-Associated Diazotroph.
  • S E Bloch
  • R Clark
  • S S Gottlieb
  • L K Wood
  • N Shah
  • S-M Mak
  • J G Lorigan
  • J Johnson
  • A G Davis-Richardson
  • L Williams
  • M McKellar
  • D Soriano
  • M Petersen
  • A Horton
  • O Smith
  • L Wu
  • E Tung
  • R Broglie
  • A Tamsir
  • K Temme
  • J. Exp. Bot..2020 Apr;eraa176. doi: 10.1093/jxb/eraa176.Epub 2020-04-08.

AIDS患者におけるサイトメガロウイルス網膜炎に続発する網膜剥離に対する網膜硝子体手術後の予後因子。A Retrospective Single-center Analysis

Prognostic Factors for Outcome after Vitrectomy for Retinal Detachment Secondary to Cytomegalovirus Retinitis in Patients with AIDS: A Retrospective Single-center Analysis.
  • Wenjun Kong
  • Yong Tao
  • Lianyong Xie
  • Kuifang Du
  • Hongwei Dong
  • Wenbin Wei
  • Ocul. Immunol. Inflamm..2020 Jul;:1-6. doi: 10.1080/09273948.2020.1764591.Epub 2020-07-07.

1470nmレーザーとラジアルファイバーを用いた大伏在静脈および小伏在静脈の無力症に対する静脈内レーザーアブレーションの好ましい長期成績

Favourable long-term results of endovenous laser ablation of great and small saphenous vein incompetence with a 1470-nm laser and radial fiber.
  • Patrizia Pavei
  • Giorgio Spreafico
  • Enrico Bernardi
  • Enzo Giraldi
  • Maurizio Ferrini
  • J Vasc Surg Venous Lymphat Disord.2020 Jun;S2213-333X(20)30351-6. doi: 10.1016/j.jvsv.2020.06.015.Epub 2020-06-26.

胎内カフェイン暴露に起因する多世代メス子孫の関節損傷は、TGFβシグナル伝達経路のH3K9脱アセチル化と相関している

Articular damages in multi-generational female offspring due to prenatal caffeine exposure correlates with H3K9 deacetylation of TGFβ signaling pathway.
  • Zhe Zhao
  • Jun Qin
  • Linguo Pei
  • Zheng He
  • Hanwen Luo
  • Jacques Magdalou
  • Liaobin Chen
  • Hui Wang
  • Toxicology.2020 Jul;:152533. S0300-483X(20)30172-4. doi: 10.1016/j.tox.2020.152533.Epub 2020-07-11.

水素発生反応の触媒性能を向上させた多孔質イリジウム・パラジウム・プランバム・ワイヤー状ナノネットワークを簡便に合成する

Facile synthesis of porous iridium-palladium-plumbum wire-like nanonetworks with boosted catalytic performance for hydrogen evolution reaction.
  • Ru-Lan Zhang
  • Jiao-Jiao Duan
  • Li-Ping Mei
  • Jiu-Ju Feng
  • Pei-Xin Yuan
  • Ai-Jun Wang
  • J Colloid Interface Sci.2020 Jul;580:99-107. S0021-9797(20)30875-4. doi: 10.1016/j.jcis.2020.06.124.Epub 2020-07-05.

Lawson 他によるレター「経皮的冠動脈インターベンションを受けた急性冠症候群患者における出血イベント予測のための PRECISE-DAPT スコアの臨床的有用性。SMART-DATE無作為化試験からの分析」について

Letter by Lawson et al Regarding Article, "Clinical Usefulness of PRECISE-DAPT Score for Predicting Bleeding Events in Patients With Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention: An Analysis From the SMART-DATE Randomized Trial".
  • Lucy Olivia Lawson
  • Ali Kirresh
  • Nidhi Shintre
  • Circ Cardiovasc Interv.2020 Jul;13(7):e009612. doi: 10.1161/CIRCINTERVENTIONS.120.009612.Epub 2020-07-17.

股関節前方直接アプローチによる全人工股関節形成術における2つの術中透視グリッド技術を用いたコンポーネントの配置精度の比較

Comparison of Component Placement Accuracy Using Two Intraoperative Fluoroscopic Grid Technologies During Direct Anterior Total Hip Arthroplasty.
  • Tyler J Thorne
  • Scott T Nishioka
  • Samantha N Andrews
  • Kristin A Mathews
  • Cass K Nakasone
  • J Arthroplasty.2020 Jun;S0883-5403(20)30718-X. doi: 10.1016/j.arth.2020.06.053.Epub 2020-06-24.

RBM20 p.R634W変異を持つ拡張型心筋症患者からの多能性幹細胞株とCRISPR/Cas9改変等原性コントロールの生成

Generation of pluripotent stem cell lines and CRISPR/Cas9 modified isogenic controls from a patient with dilated cardiomyopathy harboring a RBM20 p.R634W mutation.
  • Sabine Rebs
  • Farbod Sedaghat-Hamedani
  • Elham Kayvanpour
  • Benjamin Meder
  • Katrin Streckfuss-Bömeke
  • Stem Cell Res.2020 Jul;47:101901. S1873-5061(20)30202-6. doi: 10.1016/j.scr.2020.101901.Epub 2020-07-02.

レボドパ誘発性ジスキネジアの表現型とFosBの発現は、線条体Nurr1ではなく、FosBの発現とFisher 344対Lewisヘミパーキンソン病ラットの遺伝子型との関連を示した

Striatal Nurr1, but not FosB expression links a levodopa-induced dyskinesia phenotype to genotype in Fisher 344 vs. Lewis hemiparkinsonian rats.
  • Kathy Steece-Collier
  • Timothy J Collier
  • Jack W Lipton
  • Jennifer A Stancati
  • Mary E Winn
  • Allyson Cole-Strauss
  • Rhyomi Sellnow
  • Melissa M Conti
  • Natosha M Mercado
  • Eduardo A Nillni
  • Caryl E Sortwell
  • Fredric P Manfredsson
  • Christopher Bishop
  • Exp. Neurol..2020 Aug;330:113327. S0014-4886(20)30158-8. doi: 10.1016/j.expneurol.2020.113327.Epub 2020-05-05.

急性肝ポルフィリアスにおける肝細胞癌。米国ポルフィリアスコンソーシアム縦断研究の結果

Hepatocellular Carcinoma in Acute Hepatic Porphyrias: Results from the Longitudinal Study of the U.S. Porphyrias Consortium.
  • Behnam Saberi
  • Hetanshi Naik
  • Jessica R Overbey
  • Angelika L Erwin
  • Karl E Anderson
  • D Montgomery Bissell
  • Herbert L Bonkovsky
  • John D Phillips
  • Bruce Wang
  • Ashwani K Singal
  • Brendan M McGuire
  • Robert J Desnick
  • Manisha Balwani
  • Hepatology.2020 Jul;doi: 10.1002/hep.31460.Epub 2020-07-18.

エリスロマイシンは、DEL-1をアップレギュレートすることにより、好中球性炎症および粘膜疾患を抑制する

Erythromycin inhibits neutrophilic inflammation and mucosal disease by upregulating DEL-1.
  • Tomoki Maekawa
  • Hikaru Tamura
  • Hisanori Domon
  • Takumi Hiyoshi
  • Toshihito Isono
  • Daisuke Yonezawa
  • Naoki Hayashi
  • Naoki Takahashi
  • Koichi Tabeta
  • Takeyasu Maeda
  • Masataka Oda
  • Athanasios Ziogas
  • Vasileia Ι Alexaki
  • Triantafyllos Chavakis
  • Yutaka Terao
  • George Hajishengallis
  • JCI Insight.2020 Jun;136706. doi: 10.1172/jci.insight.136706.Epub 2020-06-30.

比較トランスクリプトームおよびメタボロームプロファイリングにより、タバコの葉の発生ダイナミクスの根底にある複雑なメカニズムが明らかになった

Comparative transcriptome and metabolomic profiling reveal the complex mechanisms underlying the developmental dynamics of tobacco leaves.
  • Wei Chang
  • Huina Zhao
  • Shizhou Yu
  • Jing Yu
  • Kai Cai
  • Wei Sun
  • Xumei Liu
  • Xiaodong Li
  • Mengna Yu
  • Shahzad Ali
  • Kai Zhang
  • Cunmin Qu
  • Bo Lei
  • Kun Lu
  • Genomics.2020 Jul;S0888-7543(20)30541-3. doi: 10.1016/j.ygeno.2020.07.005.Epub 2020-07-07.

25-OH-D3 の栄養補給は、ブロイラー飼育鶏の心機能と居住性を改善し、血圧と血管リモデリングの改善をもたらします

Dietary supplementation of 25-hydroxycholecalciferol improves cardiac function and livability in broiler breeder hens-amelioration of blood pressure and vascular remodeling.
  • Yo-Lin Yeh
  • Pao-Chia Chou
  • Yu-Hui Chen
  • Lih-Shiuh Lai
  • Thau Kiong Chung
  • Rosemary L Walzem
  • San-Yuan Huang
  • Shuen-Ei Chen
  • Poult. Sci..2020 Jul;99(7):3363-3373. S0032-5791(20)30175-9. doi: 10.1016/j.psj.2020.03.015.Epub 2020-04-17.

B型慢性肝炎患者の肝線維症の治療における漢方処方を補助するヌクレオシドアナログ。システマティックレビューとメタアナリシスのプロトコル

Nucleoside analogs assisted with Chinese compound prescription in treating hepatic fibrosis of chronic hepatitis B patients: A protocol of systematic review and meta-analysis.
  • Maoyuan Cheng
  • Xianrong Feng
  • Long Wang
  • Yu Yang
  • Li Ma
  • Baojia Wang
  • Medicine (Baltimore).2020 Jul;99(27):e21032. 00005792-202007020-00107. doi: 10.1097/MD.0000000000021032.

青海チベット高原におけるB型肝炎ウイルスの完全ゲノム解析：地理的分布、遺伝的多様性、HBsAg抗体と抗HBs抗体の共存

Complete genome analysis of hepatitis B virus in Qinghai-Tibet plateau: the geographical distribution, genetic diversity, and co-existence of HBsAg and anti-HBs antibodies.
  • He Liu
  • Liping Shen
  • Shuang Zhang
  • Feng Wang
  • Guomin Zhang
  • Zundong Yin
  • Feng Qiu
  • Xiaofeng Liang
  • Fuzhen Wang
  • Shengli Bi
  • Virol. J..2020 06;17(1):75. 10.1186/s12985-020-01350-w. doi: 10.1186/s12985-020-01350-w.Epub 2020-06-12.

トキソプラズマ・ゴンドイ感染マウスの大脳皮質におけるプリリン作動性シグナル伝達を介したレスベラトロールの神経保護的役割

Neuroprotective role of resveratrol mediated by purinergic signalling in cerebral cortex of mice infected by Toxoplasma gondii.
  • Nathieli B Bottari
  • Karine Paula Reichert
  • Mateus Fracasso
  • Anielen Dutra
  • Charles Elias Assmann
  • Henning Ulrich
  • Maria Rosa Chitolina Schetinger
  • Vera M Morsch
  • Aleksandro Schafer Da Silva
  • Parasitol. Res..2020 Jul;10.1007/s00436-020-06795-0. doi: 10.1007/s00436-020-06795-0.Epub 2020-07-17.

偏最小二乗-Pathモデリングの使用による青年期の暴力・正義化に対するアンビバレントな性差別の影響の理解

The Use of Partial Least Squares-Path Modelling to Understand the Impact of Ambivalent Sexism on Violence-Justification among Adolescents.
  • Roberto Fasanelli
  • Ida Galli
  • Maria Gabriella Grassia
  • Marina Marino
  • Rosanna Cataldo
  • Carlo Natale Lauro
  • Chiara Castiello
  • Filomena Grassia
  • Caterina Arcidiacono
  • Fortuna Procentese
  • Int J Environ Res Public Health.2020 Jul;17(14). E4991. doi: 10.3390/ijerph17144991.Epub 2020-07-10.

活動期のがん患者における血栓予防に関する実際のデータ。現在の状況は？到達しているのか？

Real-World Data on Thromboprophylaxis in Active Cancer Patients: Where Are We? Are We Getting There?
  • Nikolaos Tsoukalas
  • Pavlos Papakotoulas
  • Athina Christopoulou
  • Alexandros Ardavanis
  • Georgios Koumakis
  • Christos Papandreou
  • Georgios Papatsimpas
  • Pavlos Papakostas
  • Georgios Samelis
  • Charalambos Andreadis
  • Gerasimos Aravantinos
  • Nikolaos Ziras
  • Charalambos Kalofonos
  • Epameinondas Samantas
  • Maria Souggleri
  • Paris Makrantonakis
  • Georgios Pentheroudakis
  • Athanasios Athanasiadis
  • Helen Stergiou
  • Elli-Sofia Tripodaki
  • Alexandros Bokas
  • Anastasios Grivas
  • Eleni Timotheadou
  • Evangelos Bournakis
  • Ioannis Varthalitis
  • Ioannis Boukovinas
  • Cancers (Basel).2020 Jul;12(7). E1907. doi: 10.3390/cancers12071907.Epub 2020-07-15.

ヘッドスペース固相マイクロ抽出とガスクロマトグラフィー質量分析を組み合わせたヘッドスペース固相マイクロ抽出法によるテーブルワインおよび酒精強化ワイン中のフタル酸塩のモニタリング

Monitoring phthalates in table and fortified wines by headspace solid phase microextraction combined with gas chromatography mass spectrometry analysis.
  • Rosa Perestrelo
  • Catarina Silva
  • Manuel Algarra
  • José S Câmara
  • J. Agric. Food Chem..2020 Jul;doi: 10.1021/acs.jafc.0c02941.Epub 2020-07-10.

うつ病症状がパーソナリティ障害治療に与える影響うつ病症状がネガティブ・エフェクト表現の対人効果を増幅させる

Depression symptoms' impact on personality disorder treatment: Depression symptoms amplifying the interpersonal benefits of negative-affect expression.
  • Daniel W Cox
  • David Kealy
  • Jeffrey H Kahn
  • Katharine D McCloskey
  • Anthony S Joyce
  • John S Ogrodniczuk
  • J Affect Disord.2020 Jul;272:318-325. S0165-0327(19)31941-X. doi: 10.1016/j.jad.2020.03.133.Epub 2020-04-29.

下垂体神経内分泌腫瘍と分化型甲状腺がん：代謝性および炎症性リスク因子は役割を果たしているか？

Pituitary neuroendocrine tumors and differentiated thyroid cancer: do metabolic and inflammatory risk factors play roles?
  • G Cortês Nascimento
  • A G P de Araujo Cortês Nascimento
  • C de Maria Ribeiro Veiga Parente
  • V P Rodrigues
  • R S de Sousa Azulay
  • V C de Carvalho Rocha
  • S da Silva Pereira Damianse
  • M Magalhães
  • M Dos Santos Faria
  • M B Gomes
  • J. Endocrinol. Invest..2020 Jul;10.1007/s40618-020-01357-8. doi: 10.1007/s40618-020-01357-8.Epub 2020-07-17.

バイオソリッド中のパーフルオロアルキル、フルオテロメルスルホン酸塩、およびパーフルオロオクタンスルホンアミドの汚染。組成、共同汚染、再利用の意味合い

Perfluoroalkyl, fluorotelomer sulfonate, and perfluorooctane sulfonamide contamination in biosolids: Composition, co-contamination and re-use implications.
  • Julie A Sleep
  • Albert L Juhasz
  • Environ. Pollut..2020 Jul;266(Pt 1):115120. S0269-7491(20)32400-3. doi: 10.1016/j.envpol.2020.115120.Epub 2020-07-08.

ブラジル、サンルイス（マサチューセッツ州）のRPSコホートの青年期における日中の過剰な眠気の有病率と関連因子

Prevalence of excessive daytime sleepiness and associated factors in adolescents of the RPS cohort, in São Luís (MA), Brazil.
  • Sara Machado Miranda Leal Barbosa
  • Rosângela Fernandes Lucena Batista
  • Lívia Dos Santos Rodrigues
  • Maylla Luanna Barbosa Martins Bragança
  • Bianca Rodrigues de Oliveira
  • Vanda Maria Ferreira Simões
  • Alan Luiz Eckeli
  • Antônio Augusto Moura da Silva
  • Rev Bras Epidemiol.2020;23:e200071. S1415-790X2020000100463. doi: 10.1590/1980-549720200071.Epub 2020-07-06.

結晶化プロセスのスケール阻害と連続X線回折分析のためのマイクロフロー構成の評価

Evaluation of microflow configurations for scale inhibition and serial X-ray diffraction analysis of crystallization processes.
  • Mark A Levenstein
  • Yi-Yeoun Kim
  • Liam Hunter
  • Clara Anduix-Canto
  • Carlos González Niño
  • Sarah J Day
  • Shunbo Li
  • William J Marchant
  • Phillip A Lee
  • Chiu C Tang
  • Manfred Burghammer
  • Fiona C Meldrum
  • Nikil Kapur
  • Lab Chip.2020 Jul;doi: 10.1039/d0lc00239a.Epub 2020-07-15.

尿路力学的ストレス性尿失禁を有する女性の治療において、自己筋膜直筋膜陰部スリング手術と合成経尿道的膣テープ術の比較研究を行った

A comparative study of autologous rectus fascia pubovaginal sling surgery and synthetic transobturator vaginal tape procedure in treatment of women with urodynamic stress urinary incontinence.
  • J B Sharma
  • Manasi Kamalakar Deoghare
  • Neerja Bhatla
  • Garima Kachhawa
  • Reeta Mahey
  • Rajesh Kumari
  • Amlesh Seth
  • Alpana Sharma
  • Eur. J. Obstet. Gynecol. Reprod. Biol..2020 Jul;252:349-354. S0301-2115(20)30437-1. doi: 10.1016/j.ejogrb.2020.06.062.Epub 2020-07-03.

フローサイトメトリーによるPlasmodium vivax merozoitesの簡単なex vivoファゴサイトーシスアッセイ

A simple, ex vivo phagocytosis assay of Plasmodium vivax merozoites by flow cytometry.
  • Elizangela Farias
  • Fhabiane Bezerra
  • Djane Clarys Baia-da-Silva
  • Yury Oliveira Chaves
  • Tatiana Bacry Cardoza
  • Maria Edilene Martins de Almeida
  • Lucas Barbosa Oliveira
  • Pritesh Lalwani
  • Patrícia Puccinelli Orlandi
  • Marcus Vinicius Guimaraes Lacerda
  • Stefanie Costa Pinto Lopes
  • Paulo Afonso Nogueira
  • Mem. Inst. Oswaldo Cruz.2019;114:e190158. S0074-02762019000100419. doi: 10.1590/0074-02760190158.Epub 2019-10-07.

小麦（Triticum aestivum L.）のアブシジン酸・ストレス・成熟誘導遺伝子（ASR）ファミリーのゲノムワイドな特徴付け

Genome-wide characterization of the abscisic acid-, stress- and ripening-induced (ASR) gene family in wheat (Triticum aestivum L.).
  • Huawei Li
  • Haiying Guan
  • Qicui Zhuo
  • Zongshuai Wang
  • Shengdong Li
  • Jisheng Si
  • Bin Zhang
  • Bo Feng
  • Ling-An Kong
  • Fahong Wang
  • Zheng Wang
  • Lishun Zhang
  • Biol. Res..2020 May;53(1):23. 10.1186/s40659-020-00291-6. doi: 10.1186/s40659-020-00291-6.Epub 2020-05-24.

フラキシナス・アングスティフォリア樹皮抽出物のアルツハイマー病に対する神経保護効果

Neuroprotective effects of Fraxinus angustifolia Vahl. bark extract against Alzheimer's disease.
  • Lila Azib
  • Nadjet Debbache-Benaida
  • Gregory Da Costa
  • Dina Atmani-Kilani
  • Naima Saidene
  • Ghania Bouguellid
  • Asma Ourabah
  • Stephanie Krisa
  • Tristan Richard
  • Djebbar Atmani
  • J. Chem. Neuroanat..2020 Jul;109:101848. S0891-0618(20)30117-4. doi: 10.1016/j.jchemneu.2020.101848.Epub 2020-07-06.

ガスクロマトグラフィー-質量分析法に基づく漢方薬同風台顆粒を投与された痛風患者の血清代謝プロファイリング分析

Serum Metabolic Profiling Analysis of Gout Patients Treated with Traditional Chinese Medicine Tongfengtai Granules Based on Gas Chromatography-Mass Spectrometry.
  • Jianyong Zhang
  • Hong Pan
  • Jingjing Xie
  • Jing Wang
  • Ruyi Wang
  • Xia Qiu
  • Li Zhong
  • Tengyan Li
  • Yuya Xiao
  • Min Xiao
  • Yanying Zhang
  • Ertao Jia
  • Yubao Jiang
  • Binbin Wang
  • Evid Based Complement Alternat Med.2020;2020:7404983. doi: 10.1155/2020/7404983.Epub 2020-04-26.

インジゴイジン合成酵素BpsAは、他のNRPS酵素の基質嗜好性を定量するために適応させることができる比色ATPアッセイを提供します

The indigoidine synthetase BpsA provides a colorimetric ATP assay that can be adapted to quantify the substrate preferences of other NRPS enzymes.
  • Alistair S Brown
  • Mark J Calcott
  • Vincent M Collins
  • Jeremy G Owen
  • David F Ackerley
  • Biotechnol. Lett..2020 Jul;10.1007/s10529-020-02972-4. doi: 10.1007/s10529-020-02972-4.Epub 2020-07-17.

S-アデノシル-L-メチオニン（SAMe）は、胆管細胞における抗酸化およびS-グルタチオン化プロセスを介して、原発性胆管炎（PBC）患者の自己免疫反応を停止させます

S-adenosyl-L-methionine (SAMe) halts the autoimmune response in patients with primary biliary cholangitis (PBC) via antioxidant and S-glutathionylation processes in cholangiocytes.
  • E Kilanczyk
  • J M Banales
  • E Wunsch
  • O Barbier
  • M A Avila
  • J M Mato
  • M Milkiewicz
  • P Milkiewicz
  • Biochim Biophys Acta Mol Basis Dis.2020 Jul;:165895. S0925-4439(20)30243-X. doi: 10.1016/j.bbadis.2020.165895.Epub 2020-07-15.

新興都市化地域のアサリMeretrix meretrixに含まれる芳香族炭化水素のバイオモニタリングと人間の健康への影響

Biomonitoring of aromatic hydrocarbons in clam Meretrix meretrix from an emerging urbanization area, and implications for human health.
  • Chao Fang
  • Jun Bo
  • Ronghui Zheng
  • Fukun Hong
  • Weiming Kuang
  • Yulu Jiang
  • Jincan Chen
  • Yusheng Zhang
  • Helmut Segner
  • Ecotoxicol. Environ. Saf..2020 Apr;192:110271. S0147-6513(20)30110-X. doi: 10.1016/j.ecoenv.2020.110271.Epub 2020-02-07.

また、低pHストレス下でのPatinopecten yessoensisにおけるアルギニンキナーゼの重要な役割を構造と機能解析により明らかにした

Structure and functional analysis reveal an important regulated role of arginine kinase in Patinopecten yessoensis under low pH stress.
  • Zujing Yang
  • Xiaoting Huang
  • Huan Liao
  • Zhengrui Zhang
  • Fanhua Sun
  • Sihua Kou
  • Zhenmin Bao
  • Aquat. Toxicol..2020 May;222:105452. S0166-445X(19)30859-8. doi: 10.1016/j.aquatox.2020.105452.Epub 2020-02-19.

バングラデシュの医療従事者の間で、資格のある者と資格のない者の間で不適切な抗生物質の調剤が行われている要因は何か？質的研究

What contributes to inappropriate antibiotic dispensing among qualified and unqualified healthcare providers in Bangladesh? A qualitative study.
  • Papreen Nahar
  • Leanne Unicomb
  • Patricia Jane Lucas
  • Mohammad Rofi Uddin
  • Mohammad Aminul Islam
  • Fosiul Alam Nizame
  • Nirnita Khisa
  • S M Salim Akter
  • Emily K Rousham
  • BMC Health Serv Res.2020 Jul;20(1):656. 10.1186/s12913-020-05512-y. doi: 10.1186/s12913-020-05512-y.Epub 2020-07-15.

RNAシーケンスにより、口腔・顎顔面組織のトランスクリプトームから多能性間葉系間葉系間葉系間質細胞の位置記憶を明らかにした

RNA-sequencing reveals positional memory of multipotent mesenchymal stromal cells from oral and maxillofacial tissue transcriptomes.
  • Satoru Onizuka
  • Yasuharu Yamazaki
  • Sung-Joon Park
  • Takayuki Sugimoto
  • Yumiko Sone
  • Sebastian Sjöqvist
  • Michihiko Usui
  • Akira Takeda
  • Kenta Nakai
  • Keisuke Nakashima
  • Takanori Iwata
  • BMC Genomics.2020 Jun;21(1):417. 10.1186/s12864-020-06825-2. doi: 10.1186/s12864-020-06825-2.Epub 2020-06-22.

食事性2型耐性デンプンは、高脂肪食を摂取した高齢マウスの腸内マイクロバイオームと代謝物を調節することで、全身の炎症と腸管透過性を改善することが示された

Dietary type 2 resistant starch improves systemic inflammation and intestinal permeability by modulating microbiota and metabolites in aged mice on high-fat diet.
  • Yawen Zhang
  • Luyi Chen
  • Mengjia Hu
  • John J Kim
  • Renbin Lin
  • Jilei Xu
  • Lina Fan
  • Yadong Qi
  • Lan Wang
  • Weili Liu
  • Yanyong Deng
  • Jianmin Si
  • Shujie Chen
  • Aging (Albany NY).2020 May;12(10):9173-9187. 103187. doi: 10.18632/aging.103187.Epub 2020-05-25.

ブラジルにおけるクラック・コカイン使用障害の男女における自殺未遂の予測

Prediction of attempted suicide in men and women with crack-cocaine use disorder in Brazil.
  • Vinícius Serafini Roglio
  • Eduardo Nunes Borges
  • Francisco Diego Rabelo-da-Ponte
  • Felipe Ornell
  • Juliana Nichterwitz Scherer
  • Jaqueline Bohrer Schuch
  • Ives Cavalcante Passos
  • Breno Sanvicente-Vieira
  • Rodrigo Grassi-Oliveira
  • Lisia von Diemen
  • Flavio Pechansky
  • Felix Henrique Paim Kessler
  • PLoS ONE.2020;15(5):e0232242. PONE-D-19-17475. doi: 10.1371/journal.pone.0232242.Epub 2020-05-04.

旭日（極東アジア）の淡水イガイ（Bivalvia: Unionidae）：系統・系統・分布．

Freshwater mussels (Bivalvia: Unionidae) from the rising sun (Far East Asia): phylogeny, systematics, and distribution.
  • Manuel Lopes-Lima
  • Akimasa Hattori
  • Takaki Kondo
  • Jin Hee Lee
  • Sang Ki Kim
  • Akihisa Shirai
  • Hironori Hayashi
  • Taira Usui
  • Kanta Sakuma
  • Taishi Toriya
  • Youhei Sunamura
  • Haruki Ishikawa
  • Naoki Hoshino
  • Yushi Kusano
  • Hinata Kumaki
  • Yuya Utsugi
  • Shinnosuke Yabe
  • Yuma Yoshinari
  • Hazuki Hiruma
  • Akiko Tanaka
  • Kentaro Sao
  • Takuya Ueda
  • Isao Sano
  • Jun-Ichi Miyazaki
  • Duarte V Gonçalves
  • Olga K Klishko
  • Ekaterina S Konopleva
  • Ilya V Vikhrev
  • Alexander V Kondakov
  • Mikhail Yu Gofarov
  • Ivan N Bolotov
  • Elena M Sayenko
  • Marianna Soroka
  • Alexandra Zieritz
  • Arthur E Bogan
  • Elsa Froufe
  • Mol. Phylogenet. Evol..2020 05;146:106755. S1055-7903(20)30027-0. doi: 10.1016/j.ympev.2020.106755.Epub 2020-02-03.

スペイン南東部の第三次病院に通院している多嚢胞性卵巣症候群の女性の健康関連QOL：ケースコントロール研究

Health-related quality of life in women with polycystic ovary syndrome attending to a tertiary hospital in Southeastern Spain: a case-control study.
  • María L Sánchez-Ferrer
  • Evdochia Adoamnei
  • María T Prieto-Sánchez
  • Jaime Mendiola
  • Shiana Corbalán-Biyang
  • Miriam Moñino-García
  • Joaquín A Palomar-Rodríguez
  • Alberto M Torres-Cantero
  • Health Qual Life Outcomes.2020 Jul;18(1):232. 10.1186/s12955-020-01484-z. doi: 10.1186/s12955-020-01484-z.Epub 2020-07-16.

ナイジェリアの牧畜牛群におけるリフトバレー熱ウイルス発生の血清陽性率と関連する内因性および外因性因子：横断的調査

Seropositivity and associated intrinsic and extrinsic factors for Rift Valley fever virus occurrence in pastoral herds of Nigeria: a cross sectional survey.
  • Nma Bida Alhaji
  • Jibrin Aminu
  • Mohammed Kabiru Lawan
  • Olutayo Olajide Babalobi
  • Ibrahim Ghali-Mohammed
  • Ismail Ayoade Odetokun
  • BMC Vet. Res..2020 Jul;16(1):243. 10.1186/s12917-020-02455-8. doi: 10.1186/s12917-020-02455-8.Epub 2020-07-14.

COVID-19パンデミック初期における専門職間/学際的チームワーク：学術医療センター内の小児病院からの経験

Interprofessional/interdisciplinary teamwork during the early COVID-19 pandemic: experience from a children's hospital within an academic health center.
  • JoAnne E Natale
  • Judie Boehmer
  • Dean A Blumberg
  • Constantine Dimitriades
  • Shinjiro Hirose
  • Laura R Kair
  • J Douglas Kirk
  • Stephanie N Mateev
  • Heather McKnight
  • Jennifer Plant
  • Leah S Tzimenatos
  • Jean T Wiedeman
  • Jessica Witkowski
  • Mark A Underwood
  • Satyan Lakshminrusimha
  • J Interprof Care.2020 Jul;:1-5. doi: 10.1080/13561820.2020.1791809.Epub 2020-07-16.

救急科における自殺性の新たなエンゲージメント。自殺性の仮想的な共同評価と管理

A novel engagement of suicidality in the emergency department: Virtual Collaborative Assessment and Management of Suicidality.
  • Linda A Dimeff
  • David A Jobes
  • Samantha A Chalker
  • Brian M Piehl
  • Leticia Lobo Duvivier
  • Benjamin C Lok
  • Mohan S Zalake
  • Julie Chung
  • Kelly Koerner
  • Gen Hosp Psychiatry.2020 Mar - Apr;63:119-126. S0163-8343(18)30088-4. doi: 10.1016/j.genhosppsych.2018.05.005.Epub 2018-05-20.

ニコチンアミドモノヌクレオチドアデニル転移酵素（nmnat）を過剰発現させることで、甘皮植物の生育速度、Ca濃度、セルラーゼ産生量が増加することを明らかにした

Overexpression of nicotinamide mononucleotide adenylyltransferase (nmnat) increases the growth rate, Ca concentration and cellulase production in Ganoderma lucidum.
  • Shengli Wang
  • Jing Han
  • Jiale Xia
  • Yanru Hu
  • Liang Shi
  • Ang Ren
  • Jing Zhu
  • Mingwen Zhao
  • Appl. Microbiol. Biotechnol..2020 Jul;10.1007/s00253-020-10763-0. doi: 10.1007/s00253-020-10763-0.Epub 2020-07-07.

2013年から2019年までのニューヨーク州の蚊や哺乳類の症例から分離された東部馬蹄脳炎ウイルスと系統群の空間的・時間的拡大

Spatial and temporal expansions of Eastern equine encephalitis virus and phylogenetic groups isolated from mosquitoes and mammalian cases in New York State from 2013 to 2019.
  • JoAnne Oliver
  • Yi Tan
  • Jamie D Haight
  • Keith J Tober
  • Wayne K Gall
  • Steven D Zink
  • Laura D Kramer
  • Scott R Campbell
  • John J Howard
  • Suman R Das
  • James A Sherwood
  • Emerg Microbes Infect.2020 Dec;9(1):1638-1650. doi: 10.1080/22221751.2020.1774426.

パキージリアおよびポリミクロジリアを有する患者におけるまれな不均衡なt(Y;19)(q12;p13.2)転座に起因する非モザイクトリソミー19p13.3p13.2

Nonmosaic Trisomy 19p13.3p13.2 Resulting from a Rare Unbalanced t(Y;19)(q12;p13.2) Translocation in a Patient with Pachygyria and Polymicrogyria.
  • Daniel Martínez Anaya
  • Liliana Fernández Hernández
  • Ariadna González Del Angel
  • Miguel A Alcántara Ortigoza
  • Verónica Ulloa Avilés
  • Patricia Pérez Vera
  • Cytogenet. Genome Res..2020;160(4):177-184. 000507561. doi: 10.1159/000507561.Epub 2020-05-06.

ラベルフリー半定量液体クロマトグラフィー-タンデム質量分析プロテオミクス分析による、ホルマリン固定パラフィン包埋組織サンプル上の喉頭/下咽頭扁平上皮癌のパイロット研究

Label-Free Semiquantitative Liquid Chromatography-Tandem Mass Spectrometry Proteomics Analysis of Laryngeal/Hypopharyngeal Squamous Cell Carcinoma on Formalin-Fixed, Paraffin-Embedded Tissue Samples - a Pilot Study.
  • Andras Burian
  • Laszlo Lujber
  • Imre Gerlinger
  • Tamas Jarai
  • Eva Orosz
  • Lilla Turiak
  • Andras Acs
  • Zoltan Hegedus
  • Aniko Konigne Peter
  • Tamas Tornoczki
  • Katalin Gombos
  • Laszlo Mark
  • Pathol. Oncol. Res..2020 Jun;10.1007/s12253-020-00849-5. doi: 10.1007/s12253-020-00849-5.Epub 2020-06-21.

ドイツのブリーフ・レジリエンス尺度（BRS）の構成要素の妥当性と母集団ベースの規範

Construct Validity and Population-Based Norms of the German Brief Resilience Scale (BRS).
  • Angela M Kunzler
  • Andrea Chmitorz
  • Christiana Bagusat
  • Antonia J Kaluza
  • Isabell Hoffmann
  • Markus Schäfer
  • Oliver Quiring
  • Thomas Rigotti
  • Raffael Kalisch
  • Oliver Tüscher
  • Andreas G Franke
  • Rolf van Dick
  • Klaus Lieb
  • Eur J Health Psychol.2018;25(3):107-117. doi: 10.1027/2512-8442/a000016.Epub 2018-12-07.

後視床下部領域の電気生理学的トポグラフィーと構造的連結性。脳深部刺激のまれな兆候から学ぶことが多い

Electrophysiology and Structural Connectivity of the Posterior Hypothalamic Region: Much to Learn From a Rare Indication of Deep Brain Stimulation.
  • Bina Kakusa
  • Sabir Saluja
  • David Y A Dadey
  • Daniel A N Barbosa
  • Sandra Gattas
  • Kai J Miller
  • Robert P Cowan
  • Zepure Kouyoumdjian
  • Nader Pouratian
  • Casey H Halpern
  • Front Hum Neurosci.2020;14:164. doi: 10.3389/fnhum.2020.00164.Epub 2020-05-15.

シクロデキストリンの複合化効率に及ぼす親水性ポリマーの効果 ジフルニサルの溶解性および放出性の向上

Effect of Hydrophilic Polymers on Complexation Efficiency of Cyclodextrins in Enhancing Solubility and Release of Diflunisal.
  • Mehreen Bashir
  • Haroon Khalid Syed
  • Sajid Asghar
  • Muhammad Irfan
  • Waleed Hassan Almalki
  • Salah Ali Menshawi
  • Ikram Ullah Khan
  • Pervaiz A Shah
  • Ikrima Khalid
  • Junaid Ahmad
  • Umar Farooq Gohar
  • Kok Khiang Peh
  • Muhammad Shahid Iqbal
  • Polymers (Basel).2020 Jul;12(7). E1564. doi: 10.3390/polym12071564.Epub 2020-07-15.

ウシペスティウイルスは、多発性骨髄腫オンコロイド療法のための新しい代替ウイルスである

Bovine pestivirus is a new alternative virus for multiple myeloma oncolytic virotherapy.
  • Valentina Marchica
  • Valentina Franceschi
  • Rosanna Vescovini
  • Paola Storti
  • Emanuela Vicario
  • Denise Toscani
  • Alessia Zorzoli
  • Irma Airoldi
  • Benedetta Dalla Palma
  • Nicoletta Campanini
  • Eugenia Martella
  • Cristina Mancini
  • Federica Costa
  • Gaetano Donofrio
  • Nicola Giuliani
  • J Hematol Oncol.2020 Jul;13(1):89. 10.1186/s13045-020-00919-w. doi: 10.1186/s13045-020-00919-w.Epub 2020-07-11.

β-アドレナリン作動性のミトコンドリア活性阻害作用と血管新生阻害作用を協調させることで、腫瘍の増殖を抑制する

Coordinate β-adrenergic inhibition of mitochondrial activity and angiogenesis arrest tumor growth.
  • Cristina Nuevo-Tapioles
  • Fulvio Santacatterina
  • Konstantinos Stamatakis
  • Cristina Núñez de Arenas
  • Marta Gómez de Cedrón
  • Laura Formentini
  • José M Cuezva
  • Nat Commun.2020 Jul;11(1):3606. 10.1038/s41467-020-17384-1. doi: 10.1038/s41467-020-17384-1.Epub 2020-07-17.

肝細胞癌患者の強度変調陽子線治療計画の最適化におけるaknowledgeベースの線量-体積ヒストグラム予測モデルの役割。新しい商用システムのトレーニングと検証

The role of a knowledge based dose-volume histogram predictive model in the optimisation of intensity-modulated proton plans for hepatocellular carcinoma patients : Training and validation of a novel commercial system.
  • Luca Cozzi
  • Reynald Vanderstraeten
  • Antonella Fogliata
  • Feng-Ling Chang
  • Po-Ming Wang
  • Strahlenther Onkol.2020 Jul;10.1007/s00066-020-01664-2. doi: 10.1007/s00066-020-01664-2.Epub 2020-07-16.

重症COVID-19の肺血管症。生理学的、画像および血液学的観察

Pulmonary Angiopathy in Severe COVID-19: Physiologic, Imaging and Hematologic Observations.
  • Brijesh V Patel
  • Deepa J Arachchillage
  • Carole A Ridge
  • Paolo Bianchi
  • James F Doyle
  • Benjamin Garfield
  • Stephane Ledot
  • Cliff Morgan
  • Maurizio Passariello
  • Susanna Price
  • Suveer Singh
  • Louit Thakuria
  • Sarah Trenfield
  • Richard Trimlett
  • Christine Weaver
  • S John Wort
  • Tina Xu
  • Simon P G Padley
  • Anand Devaraj
  • Sujal R Desai
  • Am. J. Respir. Crit. Care Med..2020 Jul;doi: 10.1164/rccm.202004-1412OC.Epub 2020-07-15.

硫酸カルシウムと局所抗生物質治療のための新しい組み合わせの研究 - ceftriaxoneのほぼ一定の放出は、新しい治療法の選択肢を提供します

study of new combinations for local antibiotic therapy with calcium sulphate - Near constant release of ceftriaxone offers new treatment options.
  • Peter Wahl
  • Karolin Rönn
  • Marc Bohner
  • Laurent A Decosterd
  • Christoph Meier
  • Michel Schläppi
  • Sandrine Festa
  • Emanuel Gautier
  • J Bone Jt Infect.2018;3(4):212-221. jbjiv03p0212. doi: 10.7150/jbji.26218.Epub 2018-10-04.

外傷患者のダメージコントロール胸部外科手術における胸腔内パッキングの考え方：システマティックレビュー

The tenets of intrathoracic packing during damage control thoracic surgery for trauma patients: a systematic review.
  • Ramiro Manzano-Nunez
  • Julian Chica
  • Alexandra Gómez
  • Maria P Naranjo
  • Harold Chaves
  • Luis E Muñoz
  • Javier E Rengifo
  • Isabella Caicedo-Holguin
  • Juan C Puyana
  • Alberto F García
  • Eur J Trauma Emerg Surg.2020 Jun;10.1007/s00068-020-01428-8. doi: 10.1007/s00068-020-01428-8.Epub 2020-06-28.

カゼインホスホペプチドアモルファスリン酸カルシウムフッ化物ペーストとフッ化ナトリウム洗口剤の歯蝕予防効果の比較評価．研究

Comparative Evaluation of Casein Phosphopeptide-Amorphous Calcium Phosphate-Fluoride Paste and Sodium Fluoride Mouthwash in the Prevention of Dental Erosion: An Study.
  • Beulah M Bejoy
  • Moonnamkoottu S Sruthi
  • Liza George
  • Josey Mathew
  • Raveendran Pv Vineet
  • Aleesha Joy
  • J Contemp Dent Pract.2020 Mar;21(3):267-270. 1526-3711-2532. Epub 2020-03-01.

移行期のCFTRモジュレーター時代におけるCF治療薬のグローバル開発戦略の構築

Building global development strategies for cf therapeutics during a transitional cftr modulator era.
  • N Mayer-Hamblett
  • S van Koningsbruggen-Rietschel
  • D P Nichols
  • D R VanDevanter
  • J C Davies
  • T Lee
  • A G Durmowicz
  • F Ratjen
  • M W Konstan
  • K Pearson
  • S C Bell
  • J P Clancy
  • J L Taylor-Cousar
  • K De Boeck
  • S H Donaldson
  • D G Downey
  • P A Flume
  • P Drevinek
  • C H Goss
  • I Fajac
  • A S Magaret
  • B S Quon
  • S M Singleton
  • J M VanDalfsen
  • G Z Retsch-Bogart
  • J. Cyst. Fibros..2020 Jun;S1569-1993(20)30161-2. doi: 10.1016/j.jcf.2020.05.011.Epub 2020-06-07.

急性感染症の患者サンプルにおける活性化ベクターを用いた潜伏HIV-1の標的的再活性化

A targeted reactivation of latent HIV-1 using an activator vector in patient samples from acute infection.
  • Jamie F S Mann
  • Joshua Pankrac
  • Katja Klein
  • Paul F McKay
  • Deborah F L King
  • Richard Gibson
  • Chanuka N Wijewardhana
  • Rahul Pawa
  • Jodi Meyerowitz
  • Yong Gao
  • David H Canaday
  • Mariano Avino
  • Art F Y Poon
  • Caroline Foster
  • Sarah Fidler
  • Robin J Shattock
  • Eric J Arts
  • EBioMedicine.2020 Jul;:102853. S2352-3964(20)30228-0. doi: 10.1016/j.ebiom.2020.102853.Epub 2020-07-05.

エンベロープとRNA依存性RNAポリメラーゼ（RdRp）のコード領域を標的とした世界保健機関（WHO）承認の2つのアッセイを組み合わせたSARS-CoV-2 RT-qPCRアッセイの開発と評価（英文

Development and Evaluation of a duo SARS-CoV-2 RT-qPCR Assay Combining Two Assays Approved by the World Health Organization Targeting the Envelope and the RNA-Dependant RNA Polymerase (RdRp) Coding Regions.
  • Laura Pezzi
  • Remi N Charrel
  • Laetitia Ninove
  • Antoine Nougairede
  • Gregory Molle
  • Bruno Coutard
  • Guillaume Durand
  • Isabelle Leparc-Goffart
  • Xavier de Lamballerie
  • Laurence Thirion
  • Viruses.2020 06;12(6). E686. doi: 10.3390/v12060686.Epub 2020-06-25.

大うつ病と心代謝性特徴の遺伝的併存率：大うつ病発症年齢で層別化した

Genetic comorbidity between major depression and cardio-metabolic traits, stratified by age at onset of major depression.
  • Saskia P Hagenaars
  • Jonathan R I Coleman
  • Shing Wan Choi
  • Héléna Gaspar
  • Mark J Adams
  • David M Howard
  • Karen Hodgson
  • Matthew Traylor
  • Tracy M Air
  • Till F M Andlauer
  • Volker Arolt
  • Bernhard T Baune
  • Elisabeth B Binder
  • Douglas H R Blackwood
  • Dorret I Boomsma
  • Archie Campbell
  • Micah Cearns
  • Darina Czamara
  • Udo Dannlowski
  • Katharina Domschke
  • Eco J C de Geus
  • Steven P Hamilton
  • Caroline Hayward
  • Ian B Hickie
  • Jouke Jan Hottenga
  • Marcus Ising
  • Ian Jones
  • Lisa Jones
  • Zoltan Kutalik
  • Susanne Lucae
  • Nicholas G Martin
  • Yuri Milaneschi
  • Bertram Mueller-Myhsok
  • Michael J Owen
  • Sandosh Padmanabhan
  • Brenda W J H Penninx
  • Giorgio Pistis
  • David J Porteous
  • Martin Preisig
  • Stephan Ripke
  • Stanley I Shyn
  • Patrick F Sullivan
  • John B Whitfield
  • Naomi R Wray
  • Andrew M McIntosh
  • Ian J Deary
  • Gerome Breen
  • Cathryn M Lewis
  • Am. J. Med. Genet. B Neuropsychiatr. Genet..2020 Jul;doi: 10.1002/ajmg.b.32807.Epub 2020-07-18.

比較景観遺伝学は、タスマニアデビル（Sarcophilus harrisii）の宿主と病原体の遺伝構造に及ぼす環境の影響の違いを明らかにした

Comparative landscape genetics reveals differential effects of environment on host and pathogen genetic structure in Tasmanian devils (Sarcophilus harrisii) and their transmissible tumor.
  • Christopher P Kozakiewicz
  • Lauren Ricci
  • Austin H Patton
  • Amanda R Stahlke
  • Sarah A Hendricks
  • Mark J Margres
  • Manuel Ruiz-Aravena
  • David G Hamilton
  • Rodrigo Hamede
  • Hamish McCallum
  • Menna E Jones
  • Paul A Hohenlohe
  • Andrew Storfer
  • Mol. Ecol..2020 Jul;doi: 10.1111/mec.15558.Epub 2020-07-18.

好中球減少症および口腔内無水性潰瘍を有する患者における8番染色体の5つの不連続領域から得られたモザイク状の小さな超分子マーカー染色体

Mosaic Small Supernumerary Marker Chromosome Derived from Five Discontinuous Regions of Chromosome 8 in a Patient with Neutropenia and Oral Aphthous Ulcer.
  • Şule Altıner
  • Nüket Yürür Kutlay
  • Hatice Ilgın Ruhi
  • Cytogenet. Genome Res..2020;160(1):11-17. 000505805. doi: 10.1159/000505805.Epub 2020-01-24.

サハラ以南のアフリカにおける化学物質へのヒトの食餌曝露：総合的な食餌調査による安全性評価

Human dietary exposure to chemicals in sub-Saharan Africa: safety assessment through a total diet study.
  • Luc Ingenbleek
  • Philippe Verger
  • Marie-Madeleine Gimou
  • Abimbola Adegboye
  • Samson B Adebayo
  • Sètondji Epiphane Hossou
  • Abdoulaye Zié Koné
  • Eric Jazet
  • Anaclet D Dzossa
  • Julius Ogungbangbe
  • Sylvestre Dansou
  • Zima J Diallo
  • Petru Jitaru
  • Thierry Guérin
  • Lionel Lopes-Pereira
  • Renwei Hu
  • Michael Sulyok
  • Rudolf Krska
  • Philippe Marchand
  • Bruno Le Bizec
  • Sara Eyangoh
  • Jean Kamanzi
  • Blaise Ouattara
  • Caroline Merten
  • Markus Lipp
  • Renata Clarke
  • Jean-Charles Leblanc
  • Lancet Planet Health.2020 Jul;4(7):e292-e300. S2542-5196(20)30104-2. doi: 10.1016/S2542-5196(20)30104-2.

TRM7/FTSJ1タンパク質によるtRNA 2'-O-メチル化がショウジョウバエのスモールRNAサイレンシングを制御することを明らかにした

tRNA 2'-O-methylation by a duo of TRM7/FTSJ1 proteins modulates small RNA silencing in Drosophila.
  • Margarita T Angelova
  • Dilyana G Dimitrova
  • Bruno Da Silva
  • Virginie Marchand
  • Caroline Jacquier
  • Cyrinne Achour
  • Mira Brazane
  • Catherine Goyenvalle
  • Valérie Bourguignon-Igel
  • Salman Shehzada
  • Souraya Khouider
  • Tina Lence
  • Vincent Guerineau
  • Jean-Yves Roignant
  • Christophe Antoniewski
  • Laure Teysset
  • Damien Bregeon
  • Yuri Motorin
  • Matthias R Schaefer
  • Clément Carré
  • Nucleic Acids Res..2020 02;48(4):2050-2072. 5707191. doi: 10.1093/nar/gkaa002.

ネオアジュバント化学放射線療法に対する局所進行直腸癌の不応性を予測するための治療前T2-WIベースのラジオミクス特徴。予備的研究

Pre-Treatment T2-WI Based Radiomics Features for Prediction of Locally Advanced Rectal Cancer Non-Response to Neoadjuvant Chemoradiotherapy: A Preliminary Study.
  • Bianca Petresc
  • Andrei Lebovici
  • Cosmin Caraiani
  • Diana Sorina Feier
  • Florin Graur
  • Mircea Marian Buruian
  • Cancers (Basel).2020 Jul;12(7). E1894. doi: 10.3390/cancers12071894.Epub 2020-07-14.

ゲノムワイドな関連性とマルチゲノム解析により、ACTN2が心不全に関連する遺伝子であることが明らかになった

Genome-wide association and multi-omic analyses reveal ACTN2 as a gene linked to heart failure.
  • Marios Arvanitis
  • Emmanouil Tampakakis
  • Yanxiao Zhang
  • Wei Wang
  • Adam Auton
  • Diptavo Dutta
  • Stephanie Glavaris
  • Ali Keramati
  • Nilanjan Chatterjee
  • Neil C Chi
  • Bing Ren
  • Wendy S Post
  • Alexis Battle
  • Nat Commun.2020 02;11(1):1122. 10.1038/s41467-020-14843-7. doi: 10.1038/s41467-020-14843-7.Epub 2020-02-28.

Protaetia brevitarsisの幼虫は、Auricularia auriculaやLentinula edodesの栽培から得られた使用済みキノコ基質を食べて変換することができる

Protaetia brevitarsis larvae can feed on and convert spent mushroom substrate from Auricularia auricula and Lentinula edodes cultivation.
  • Panpan Wei
  • Yimei Li
  • Deqiang Lai
  • Lili Geng
  • Chunqin Liu
  • Jie Zhang
  • Changlong Shu
  • Rongmei Liu
  • Waste Manag.2020 Jul;114:234-239. S0956-053X(20)30375-5. doi: 10.1016/j.wasman.2020.07.009.Epub 2020-07-15.

ミニインプラント補助急速口蓋拡大術は、従来の急速口蓋拡大術に比べて頬側歯槽骨への影響が少ないか-システマティックレビューとメタアナリシス

Is the buccal alveolar bone less affected by mini-implant assisted rapid palatal expansion than by conventional rapid palatal expansion?-A systematic review and meta-analysis.
  • Flávio Mendonça Copello
  • Guido Artemio Marañón-Vásquez
  • Daniel Paludo Brunetto
  • Luciana Duarte Caldas
  • Daniele Masterson
  • Lucianne Cople Maia
  • Eduardo Franzotti Sant'Anna
  • Orthod Craniofac Res.2020 Aug;23(3):237-249. doi: 10.1111/ocr.12374.Epub 2020-04-16.

イラン、ラシュト州Razi病院の腎臓移植患者におけるCovid-19肺炎の臨床的特徴と転帰

Clinical Characteristics and Outcome of Covid-19 Pneumonia in kidney Transplant Recipients in Razi hospital, Rasht, Iran.
  • Ali Monfared
  • Simin Dashti-Khavidaki
  • Ramezan Jafari
  • Atefeh Jafari
  • Elham Ramezanzade
  • Mohamad-Kazem Lebadi
  • Yalda Haghdar-Saheli
  • Pegah Aghajanzadeh
  • Masoud Khosravi
  • Ali Movassaghi
  • Hamidreza Taghvaye-Masoumi
  • Ali Alavi Foumani
  • Transpl Infect Dis.2020 Jul;:e13420. doi: 10.1111/tid.13420.Epub 2020-07-18.

顆粒腫性-リンパ球性間質性肺疾患を合併したHuman immunodeficiency virus-associated vacuolar encephalomyelopathyが抗レトロウイルス療法後に改善した症例報告

Human immunodeficiency virus-associated vacuolar encephalomyelopathy with granulomatous-lymphocytic interstitial lung disease improved after antiretroviral therapy: a case report.
  • Kazumasa Akagi
  • Kazuko Yamamoto
  • Asuka Umemura
  • Shotaro Ide
  • Tatsuro Hirayama
  • Takahiro Takazono
  • Yoshifumi Imamura
  • Taiga Miyazaki
  • Noriho Sakamoto
  • Hirokazu Shiraishi
  • Hideaki Takahata
  • Yoshiaki Zaizen
  • Junya Fukuoka
  • Minoru Morikawa
  • Kazuto Ashizawa
  • Katsuji Teruya
  • Koichi Izumikawa
  • Hiroshi Mukae
  • AIDS Res Ther.2020 Jul;17(1):38. 10.1186/s12981-020-00295-y. doi: 10.1186/s12981-020-00295-y.Epub 2020-07-09.

高速液体クロマトグラフィーとエレクトロスプレーイオン化および四重極飛行時間型質量分析法によるDioscorea septemlobaのケミカルプロファイリング

Chemical profiling of Dioscorea septemloba by High Performance Liquid Chromatography Coupled to Electrospray Ionization and Quadrupole Time-of-Flight Mass Spectrometry.
  • Yun Ling
  • Lu Chen
  • Dan Wang
  • Xin Xiao
  • Wenjing Xu
  • Hui Yan
  • Hongling Yu
  • Qing Zhang
  • Weihong Qu
  • Jian Chen
  • Xiaohong Ji
  • Qunying Yu
  • J Chromatogr Sci.2020 Jul;bmaa039. doi: 10.1093/chromsci/bmaa039.Epub 2020-07-17.

STEMIに対する一次PCI後の完全血行再建術の有益性は年齢の上昇によって減衰する。DANAMI-3-PRIMULTI無作為化試験の結果

The benefit of complete revascularization after primary PCI for STEMI is attenuated by increasing age: Results from the DANAMI-3-PRIMULTI randomized study.
  • Francis R Joshi
  • Jacob Lønborg
  • Golnaz Sadjadieh
  • Steffen Helqvist
  • Lene Holmvang
  • Rikke Sørensen
  • Erik Jørgensen
  • Frants Pedersen
  • Hans Henrik Tilsted
  • Dan Høfsten
  • Lars Køber
  • Henning Kelbaek
  • Thomas Engstrøm
  • Catheter Cardiovasc Interv.2020 Jul;doi: 10.1002/ccd.29131.Epub 2020-07-18.

銅触媒を用いた環状ジアリールヨードニウム塩を用いたニトリル類の選択的アリール化反応。ジアリールメタンアミドの構造的に多様化した神経保護・抗がん作用を有するジアリールメタンアミドへの直接アクセス

Copper-Catalyzed Selective Arylation of Nitriles with Cyclic Diaryl Iodonium Salts: Direct Access to Structurally Diversified Diarylmethane Amides with Potential Neuroprotective and Anticancer Activities.
  • Xiaopeng Peng
  • Zhiqiang Sun
  • Peihua Kuang
  • Ling Li
  • Jingxuan Chen
  • Jianjun Chen
  • Org. Lett..2020 Jul;doi: 10.1021/acs.orglett.0c01829.Epub 2020-07-17.

フレーズ産子牛の心血管系の発育異常として、フラロット四徴症、右心室二重出口、卵巣孔特許、持続性右大動脈弓などの異常が報告されています

An unusual presentation of developmental anomalies of the cardiovascular system including tetralogy of fallot, double outlet right ventricle, patent foramen ovale and persistent right aortic arch in a Friesian calf.
  • Aine McManus
  • Tim Moloney
  • Pamela Kelly
  • Conor Rowan
  • Cliona Skelly
  • Catherine I McAloon
  • BMC Vet. Res..2020 Jun;16(1):224. 10.1186/s12917-020-02439-8. doi: 10.1186/s12917-020-02439-8.Epub 2020-06-30.

メキシコの成人における砂糖甘味飲料への課税と清涼飲料消費との関連性：Health Workers Cohort Studyのオープンコホート縦断分析

Association between tax on sugar sweetened beverages and soft drink consumption in adults in Mexico: open cohort longitudinal analysis of Health Workers Cohort Study.
  • Luz María Sánchez-Romero
  • Francisco Canto-Osorio
  • Romina González-Morales
  • M Arantxa Colchero
  • Shu-Wen Ng
  • Paula Ramírez-Palacios
  • Jorge Salmerón
  • Tonatiuh Barrientos-Gutiérrez
  • BMJ.2020 May;369:m1311. doi: 10.1136/bmj.m1311.Epub 2020-05-06.

高齢者における穿孔性消化性潰瘍の腹腔鏡下修復術。FRAILESELイタリア多施設プロスペクティブコホート研究の中間解析

Laparoscopic Repair of Perforated Peptic Ulcer in the Elderly: An Interim Analysis of the FRAILESEL Italian Multicenter Prospective Cohort Study.
  • Pietro Fransvea
  • Gianluca Costa
  • Luca Lepre
  • Mauro Podda
  • Alessio Giordano
  • Giovanni Bellanova
  • Ferdinando Agresta
  • Pierluigi Marini
  • Gabriele Sganga
  • Surg Laparosc Endosc Percutan Tech.2020 Jul;doi: 10.1097/SLE.0000000000000826.Epub 2020-07-14.

労働者の安全、健康、ウェルビーイングを改善するための商業建設下請け業者のための参加型総合労働者健康組織介入の設計。ARM for Subs」トライアル

Designing a Participatory Total Worker Health Organizational Intervention for Commercial Construction Subcontractors to Improve Worker Safety, Health, and Well-Being: The "ARM for Subs" Trial.
  • Susan E Peters
  • Hao D Trieu
  • Justin Manjourides
  • Jeffrey N Katz
  • Jack T Dennerlein
  • Int J Environ Res Public Health.2020 Jul;17(14). E5093. doi: 10.3390/ijerph17145093.Epub 2020-07-15.

新生児の食事は、母乳または粉ミルクを与えられた乳児の異なる年齢での糞便マイクロバイオータとメタボロームプロファイルを変化させる

Neonatal diet alters fecal microbiota and metabolome profiles at different ages in infants fed breast milk or formula.
  • Lauren R Brink
  • Kelly E Mercer
  • Brian D Piccolo
  • Sree V Chintapalli
  • Ahmed Elolimy
  • Anne K Bowlin
  • Katelin S Matazel
  • Lindsay Pack
  • Sean H Adams
  • Kartik Shankar
  • Thomas M Badger
  • Aline Andres
  • Laxmi Yeruva
  • Am. J. Clin. Nutr..2020 06;111(6):1190-1202. 5824718. doi: 10.1093/ajcn/nqaa076.

MG53は、リアノジン受容体を介した細胞内カルシウムシグナル伝達の調節を介して、インターフェロン-βや炎症を抑制する

MG53 suppresses interferon-β and inflammation via regulation of ryanodine receptor-mediated intracellular calcium signaling.
  • Matthew Sermersheim
  • Adam D Kenney
  • Pei-Hui Lin
  • Temet M McMichael
  • Chuanxi Cai
  • Kristyn Gumpper
  • T M Ayodele Adesanya
  • Haichang Li
  • Xinyu Zhou
  • Ki-Ho Park
  • Jacob S Yount
  • Jianjie Ma
  • Nat Commun.2020 Jul;11(1):3624. 10.1038/s41467-020-17177-6. doi: 10.1038/s41467-020-17177-6.Epub 2020-07-17.

11～13歳の子どもを対象に、精神疾患の症状を予防するために参加率を高めることを目的とした作業療法介入のクラスター無作為化比較試験

Cluster-randomised controlled trial of an occupational therapy intervention for children aged 11-13 years, designed to increase participation to prevent symptoms of mental illness.
  • Ema Tokolahi
  • Alain C Vandal
  • Paula Kersten
  • Janet Pearson
  • Clare Hocking
  • Child Adolesc Ment Health.2018 Nov;23(4):313-327. doi: 10.1111/camh.12270.Epub 2018-03-24.

膀胱上皮細胞の細胞骨格の変化を引き起こし、非リソソーム液胞形成を誘導する液胞化オートトランスポーター毒素（Vat）

The Vacuolating Autotransporter Toxin (Vat) of Causes Cell Cytoskeleton Changes and Produces Non-lysosomal Vacuole Formation in Bladder Epithelial Cells.
  • Juan Manuel Díaz
  • Charles M Dozois
  • Francisco Javier Avelar-González
  • Eduardo Hernández-Cuellar
  • Pravil Pokharel
  • Alfredo Salazar de Santiago
  • Alma Lilian Guerrero-Barrera
  • Front Cell Infect Microbiol.2020;10:299. doi: 10.3389/fcimb.2020.00299.Epub 2020-06-26.

中国北部平原における化石主導の二次的無機質PM増強。炭素と窒素の同位体比からの証拠

Fossil-driven secondary inorganic PM enhancement in the North China Plain: Evidence from carbon and nitrogen isotopes.
  • Saehee Lim
  • Xiaoyang Yang
  • Meehye Lee
  • Gang Li
  • Yuanguan Gao
  • Xiaona Shang
  • Kai Zhang
  • Claudia I Czimczik
  • Xiaomei Xu
  • Min-Suk Bae
  • Kwang-Joo Moon
  • Kwonho Jeon
  • Environ. Pollut..2020 Jul;266(Pt 2):115163. S0269-7491(19)34370-2. doi: 10.1016/j.envpol.2020.115163.Epub 2020-07-06.

Corrigendum to "Uric acid is associated with long-term adverse cardiovascular outcomes in patients with acute coronary syndrome undergoing percutaneous coronary intervention" Atherosclerosis 270 (2018) 173-179

Corrigendum to "Uric acid is associated with long-term adverse cardiovascular outcomes in patients with acute coronary syndrome undergoing percutaneous coronary intervention" [Atherosclerosis 270 (2018) 173-179].
  • Maximilian Tscharre
  • Robert Herman
  • Miklos Rohla
  • Christina Hauser
  • Serdar Farhan
  • Matthias K Freynhofer
  • Kurt Huber
  • Thomas W Weiss
  • Atherosclerosis.2020 Jul;S0021-9150(20)30243-4. doi: 10.1016/j.atherosclerosis.2020.05.001.Epub 2020-07-13.

臨床的にラテラルコンパートメントリンパ節が関与している乳頭状甲状腺癌患者に予防的中央コンパートメント頸部郭清は必要か？

Is a Prophylactic Central Compartment Neck Dissection Required in Papillary Thyroid Carcinoma Patients with Clinically Involved Lateral Compartment Lymph Nodes?
  • Victoria Harries
  • Marlena McGill
  • Laura Y Wang
  • R Michael Tuttle
  • Richard J Wong
  • Ashok R Shaha
  • Jatin P Shah
  • Snehal G Patel
  • Ian Ganly
  • Ann. Surg. Oncol..2020 Jul;10.1245/s10434-020-08861-4. doi: 10.1245/s10434-020-08861-4.Epub 2020-07-17.

高ダイナミックレンジ(HDR)輝度下での急激な暗転は、高コントラストのターゲットと輝度類似性によるグループ化を促進する

Abrupt darkening under high dynamic range (HDR) luminance invokes facilitation for high-contrast targets and grouping by luminance similarity.
  • Chou P Hung
  • Chloe Callahan-Flintoft
  • Paul D Fedele
  • Kim F Fluitt
  • Onyekachi Odoemene
  • Anthony J Walker
  • Andre V Harrison
  • Barry D Vaughan
  • Matthew S Jaswa
  • Min Wei
  • J Vis.2020 Jul;20(7):9. 2770298. doi: 10.1167/jov.20.7.9.

オロキシリンAと溶質輸送体とATP結合カセット輸送体との相互作用。このフラボノイドの薬物トランスポータープロファイル

Interactions between Oroxylin A with the solute carrier transporters and ATP-binding cassette transporters: Drug transporters profile for this flavonoid.
  • Guanghui Ren
  • Zhiying Qin
  • Nan Yang
  • Huili Chen
  • Kejia Fu
  • Chengcan Lu
  • Yang Lu
  • Ning Li
  • Yongjie Zhang
  • Xijing Chen
  • Di Zhao
  • Chem. Biol. Interact..2020 Jun;324:109097. S0009-2797(19)32115-5. doi: 10.1016/j.cbi.2020.109097.Epub 2020-04-16.

症候性膵液回収に対するルーメンアポージングカバード自己拡張金属ステント：CT および MRI を用いた転帰と合併症の評価

Lumen-apposing covered self-expanding metallic stent for symptomatic pancreatic fluid collections: assessment of outcomes and complications with CT and MRI.
  • Khoschy Schawkat
  • Michael Luo
  • Kristy Lee
  • Kevin Beker
  • Mizrahi Meir
  • Tyler M Berzin
  • Koenraad J Mortele
  • Abdom Radiol (NY).2020 Jul;10.1007/s00261-020-02638-9. doi: 10.1007/s00261-020-02638-9.Epub 2020-07-17.

腫瘍は免疫を回避するためにT細胞でde novoステロイド生合成を誘導します

Tumors induce de novo steroid biosynthesis in T cells to evade immunity.
  • Bidesh Mahata
  • Jhuma Pramanik
  • Louise van der Weyden
  • Krzysztof Polanski
  • Gozde Kar
  • Angela Riedel
  • Xi Chen
  • Nuno A Fonseca
  • Kousik Kundu
  • Lia S Campos
  • Edward Ryder
  • Graham Duddy
  • Izabela Walczak
  • Klaus Okkenhaug
  • David J Adams
  • Jacqueline D Shields
  • Sarah A Teichmann
  • Nat Commun.2020 Jul;11(1):3588. 10.1038/s41467-020-17339-6. doi: 10.1038/s41467-020-17339-6.Epub 2020-07-17.

成人の血糖値指数と脂質プロファイルに対するグリーンコーヒー抽出物サプリメントの効果：臨床試験のシステマティックレビューと用量反応メタアナリシス

The effects of green coffee extract supplementation on glycemic indices and lipid profile in adults: a systematic review and dose-response meta-analysis of clinical trials.
  • Omid Asbaghi
  • Mehdi Sadeghian
  • Morteza Nasiri
  • Mahmoud Khodadost
  • Azad Shokri
  • Bahman Panahande
  • Aliyar Pirouzi
  • Omid Sadeghi
  • Nutr J.2020 Jul;19(1):71. 10.1186/s12937-020-00587-z. doi: 10.1186/s12937-020-00587-z.Epub 2020-07-14.

イランの4つの教育病院から分離されたメチシリン耐性黄色ブドウ球菌の分子解析：新規MRSAクローンの出現

Molecular analysis of methicillin-resistant Staphylococcus aureus isolates from four teaching hospitals in Iran: the emergence of novel MRSA clones.
  • Farzaneh Firoozeh
  • Mitra Omidi
  • Mahmood Saffari
  • Hossein Sedaghat
  • Mohammad Zibaei
  • Antimicrob Resist Infect Control.2020 Jul;9(1):112. 10.1186/s13756-020-00777-8. doi: 10.1186/s13756-020-00777-8.Epub 2020-07-17.

複数の次世代シークエンシングプラットフォームを用いたMICA遺伝子のゲノム特性評価。バリデーション研究

Genomic characterization of MICA gene using multiple next generation sequencing platforms: A validation study.
  • Yizhou Zou
  • Jamie L Duke
  • Deborah Ferriola
  • Qizhi Luo
  • Jenna Wasserman
  • Timothy L Mosbruger
  • Weiguang Luo
  • Liang Cai
  • Kevin Zou
  • Nikolaos Tairis
  • Georgios Damianos
  • Ioanna Pagkrati
  • Debra Kukuruga
  • Yanping Huang
  • Dimitri Monos
  • HLA.2020 Jul;doi: 10.1111/tan.13998.Epub 2020-07-18.

不妊クリニックに通院している男性25,445人の年齢と精子クロマチン構造アッセイ（SCSA®）との関係は、精子のDNAとクロマチンの完全性を定義した

Relationships between the age of 25,445 men attending infertility clinics and sperm chromatin structure assay (SCSA®) defined sperm DNA and chromatin integrity.
  • Donald P Evenson
  • Gemechis Djira
  • Kay Kasperson
  • Jennifer Christianson
  • Fertil. Steril..2020 Jul;S0015-0282(20)30304-6. doi: 10.1016/j.fertnstert.2020.03.028.Epub 2020-07-08.

PET/MR心筋灌流イメージングにおける心筋クリープ誘発性ミスアライメントアーチファクト

Myocardial creep-induced misalignment artifacts in PET/MR myocardial perfusion imaging.
  • Elia von Felten
  • Georgios Benetos
  • Dimitri Patriki
  • Dominik C Benz
  • Georgios P Rampidis
  • Andreas A Giannopoulos
  • Adam Bakula
  • Christoph Gräni
  • Aju P Pazhenkottil
  • Catherine Gebhard
  • Tobias A Fuchs
  • Philipp A Kaufmann
  • Ronny R Buechel
  • Eur. J. Nucl. Med. Mol. Imaging.2020 Jul;10.1007/s00259-020-04956-y. doi: 10.1007/s00259-020-04956-y.Epub 2020-07-18.

高あくびをしたラットと低あくびをしたラットとでは、砂糖を長時間摂取した後の味覚連想学習能力が異なることが明らかになった

Taste association capabilities differ in high- and low-yawning rats versus outbred Sprague-Dawley rats after prolonged sugar consumption.
  • María-Isabel Miranda
  • Alejandro Rangel-Hernández
  • Gabriela Vera-Rivera
  • Carmen Cortes
  • Jose R Eguibar
  • Anim Cogn.2020 Jul;10.1007/s10071-020-01415-x. doi: 10.1007/s10071-020-01415-x.Epub 2020-07-17.

腎移植患者におけるCOVID-19。イスタンブールにおける多施設共同研究の経験

COVID-19 in kidney transplant recipients: A multicenter experience in Istanbul.
  • Erol Demir
  • Murathan Uyar
  • Ergun Parmaksiz
  • Ayse Sinangil
  • Berna Yelken
  • Ahmet Burak Dirim
  • Ozgur Merhametsiz
  • Serap Yadigar
  • Zuhal Atan Ucar
  • Ali Riza Ucar
  • Mehmet Emin Demir
  • Meral Mese
  • Emin Baris Akin
  • Nurana Garayeva
  • Seda Safak
  • Ozgur Akin Oto
  • Halil Yazici
  • Aydin Turkmen
  • Transpl Infect Dis.2020 Jul;:e13371. doi: 10.1111/tid.13371.Epub 2020-07-13.

Arg541残基を含むLMNAバリアントの遺伝子型-フェノタイプ相関：マルチモダリティイメージングと文献レビューを含む症例報告

Genotype-phenotype correlation of LMNA variants involving the Arg541 residue: a case report with multimodality imaging and literature review.
  • Andrea Di Marco
  • María Ruiz-Cueto
  • Joel Salazar-Mendiguchía
  • Eduard Claver
  • Gerard Roura
  • Paolo Domenico Dallaglio
  • Ignasi Anguera
  • ESC Heart Fail.2020 Jul;doi: 10.1002/ehf2.12776.Epub 2020-07-15.

アトランティックサーモンにおけるサケのアルファウイルス負荷に関連する定量的形質遺伝子座と遺伝子：膵臓疾患抵抗性と耐性への影響

Quantitative trait loci and genes associated with salmonid alphavirus load in Atlantic salmon: implications for pancreas disease resistance and tolerance.
  • M L Aslam
  • D Robledo
  • A Krasnov
  • H K Moghadam
  • B Hillestad
  • R D Houston
  • M Baranski
  • S Boison
  • N A Robinson
  • Sci Rep.2020 Jun;10(1):10393. 10.1038/s41598-020-67405-8. doi: 10.1038/s41598-020-67405-8.Epub 2020-06-25.

比較トランスクリプトーム解析の結果、複数のホルモンシグナル伝達と炭水化物代謝経路がニコチアナ・タバカムのバチルス・セレウスによって影響を受けていることが明らかになった

Comparative transcriptomic analysis reveals that multiple hormone signal transduction and carbohydrate metabolic pathways are affected by Bacillus cereus in Nicotiana tabacum.
  • Yueyue Li
  • Min Zhao
  • Wenwen Chen
  • Hongyi Du
  • Xiaodong Xie
  • Daibin Wang
  • Ya Dai
  • Qingyou Xia
  • Genhong Wang
  • Genomics.2020 Jul;S0888-7543(20)30032-X. doi: 10.1016/j.ygeno.2020.07.022.Epub 2020-07-14.

慢性非がん性疼痛に対する非オピオイド鎮痛薬と比較した長期オピオイド治療を受けている患者の全死亡率：データベース研究

All-cause mortality in patients with long-term opioid therapy compared with non-opioid analgesics for chronic non-cancer pain: a database study.
  • Winfried Häuser
  • Tino Schubert
  • Tobias Vogelmann
  • Christoph Maier
  • Mary-Ann Fitzcharles
  • Thomas Tölle
  • BMC Med.2020 Jul;18(1):162. 10.1186/s12916-020-01644-4. doi: 10.1186/s12916-020-01644-4.Epub 2020-07-15.

蝸牛毛細胞の完全性は、Dia1の先端接合複合体およびステレオシリアにおける局在化を通して確立され、維持される

The integrity of cochlear hair cells is established and maintained through the localization of Dia1 at apical junctional complexes and stereocilia.
  • Yuzuru Ninoyu
  • Hirofumi Sakaguchi
  • Chen Lin
  • Toshiaki Suzuki
  • Shigeru Hirano
  • Yasuo Hisa
  • Naoaki Saito
  • Takehiko Ueyama
  • Cell Death Dis.2020 Jul;11(7):536. 10.1038/s41419-020-02743-z. doi: 10.1038/s41419-020-02743-z.Epub 2020-07-16.

高静水圧前処理による熟成ニンニクのγ-グルタミルトランスフェラーゼ活性とS-アリル-(L)-システインの酵素合成促進戦略

A strategy for promoting γ-glutamyltransferase activity and enzymatic synthesis of S-allyl-(L)-cysteine in aged garlic via high hydrostatic pressure pretreatments.
  • Yu-Ting Chen
  • Yi-An Chen
  • Chieh-Hsiu Lee
  • Jung-Tsung Wu
  • Kuan-Chen Cheng
  • Chang-Wei Hsieh
  • Food Chem.2020 Jun;316:126347. S0308-8146(20)30201-6. doi: 10.1016/j.foodchem.2020.126347.Epub 2020-02-04.

ショウジョウバエのGr28bDプロダクトは、新規な熱遺伝学的ツールとして使用できる非特異的なカチオンチャネルです

The Drosophila Gr28bD product is a non-specific cation channel that can be used as a novel thermogenetic tool.
  • Aditi Mishra
  • Autoosa Salari
  • Benton R Berigan
  • Kayla C Miguel
  • Marzie Amirshenava
  • Abbey Robinson
  • Benjamin C Zars
  • Jenna L Lin
  • Lorin S Milescu
  • Mirela Milescu
  • Troy Zars
  • Sci Rep.2018 01;8(1):901. 10.1038/s41598-017-19065-4. doi: 10.1038/s41598-017-19065-4.Epub 2018-01-17.

TRPC1/4/5チャンネルのピコモル、選択的、サブタイプ特異的な低分子阻害作用

Picomolar, selective, and subtype-specific small-molecule inhibition of TRPC1/4/5 channels.
  • Hussein N Rubaiy
  • Melanie J Ludlow
  • Matthias Henrot
  • Hannah J Gaunt
  • Katarina Miteva
  • Sin Ying Cheung
  • Yasuyuki Tanahashi
  • Nurasyikin Hamzah
  • Katie E Musialowski
  • Nicola M Blythe
  • Hollie L Appleby
  • Marc A Bailey
  • Lynn McKeown
  • Roger Taylor
  • Richard Foster
  • Herbert Waldmann
  • Peter Nussbaumer
  • Mathias Christmann
  • Robin S Bon
  • Katsuhiko Muraki
  • David J Beech
  • J. Biol. Chem..2017 05;292(20):8158-8173. M116.773556. doi: 10.1074/jbc.M116.773556.Epub 2017-03-21.

中国南部珠江デルタ地域の黒オドラス河川の堆積物中の薄膜中の拡散性勾配によるリン，鉄，硫黄のその場高分解能測定を行った

In situ high-resolution measurement of phosphorus, iron and sulfur by diffusive gradients in thin films in sediments of black-odorous rivers in the Pearl River Delta region, South China.
  • Nan Rong
  • Wenzhou Lu
  • Chaoyu Zhang
  • Yishu Wang
  • Jialiang Zhu
  • Wenqiang Zhang
  • Pei Lei
  • Environ. Res..2020 Jul;189:109918. S0013-9351(20)30813-6. doi: 10.1016/j.envres.2020.109918.Epub 2020-07-11.

金色ポンパノ（Trachinotus ovatus）由来のヘムオキシゲナーゼ-1の同定と銅による酸化ストレスに対するNrf2/HO-1シグナル伝達経路の応答

Identification of heme oxygenase-1 from golden pompano (Trachinotus ovatus) and response of Nrf2/HO-1 signaling pathway to copper-induced oxidative stress.
  • Jiajun Xie
  • Xuanshu He
  • Haohang Fang
  • Shiyu Liao
  • Yongjian Liu
  • Lixia Tian
  • Jin Niu
  • Chemosphere.2020 Aug;253:126654. S0045-6535(20)30847-X. doi: 10.1016/j.chemosphere.2020.126654.Epub 2020-04-08.

ダイナミン関連タンパク質1（Drp1）の欠損は表皮の発育やUVB誘発性アポトーシスには影響しないが、UVB誘発性発がんを促進する

Loss of dynamin-related protein 1 (Drp1) does not affect epidermal development or UVB-induced apoptosis but does accelerate UVB-induced carcinogenesis.
  • Teruki Yanagi
  • Shinya Kitamura
  • Keisuke Imafuku
  • Asuka Suto
  • Takuya Maeda
  • Shinya Tanaka
  • Hiromi Sesaki
  • Riichiro Abe
  • Hiroshi Shimizu
  • J. Dermatol. Sci..2020 Jun;S0923-1811(20)30207-3. doi: 10.1016/j.jdermsci.2020.06.009.Epub 2020-06-26.

ミャンマー東部および西部国境地帯に生息するPlasmodium vivax Duffy-binding protein遺伝子の遺伝的多様性、自然選択およびハプロタイプのグループ化

Genetic diversity, natural selection and haplotype grouping of Plasmodium vivax Duffy-binding protein genes from eastern and western Myanmar borders.
  • Yubing Hu
  • Lin Wang
  • Huguette Gaelle Ngassa Mbenda
  • Myat Thu Soe
  • Chunyun Yu
  • Hui Feng
  • Myat Phone Kyaw
  • Liwang Cui
  • Xiaotong Zhu
  • Yaming Cao
  • Parasit Vectors.2019 Nov;12(1):546. 10.1186/s13071-019-3803-2. doi: 10.1186/s13071-019-3803-2.Epub 2019-11-20.

エキストラバージンオリーブオイルを担持したアクティブな食用シュガーパームデンプンキトサンフィルム。バリア性、熱力学的特性、抗酸化性、抗菌性

Active edible sugar palm starch-chitosan films carrying extra virgin olive oil: Barrier, thermo-mechanical, antioxidant, and antimicrobial properties.
  • M Hasan
  • Rusman Rusman
  • Ibnu Khaldun
  • Linda Ardana
  • Mudatsir Mudatsir
  • H Fansuri
  • Int. J. Biol. Macromol..2020 Jul;163:766-775. S0141-8130(20)33830-7. doi: 10.1016/j.ijbiomac.2020.07.076.Epub 2020-07-11.

一次人工膝関節置換術におけるトブラマイシンとバンコマイシンの局所送達は、急性人工関節感染症の原因となる一般細菌の最小阻害濃度を達成している

Local delivery of tobramycin and vancomycin in primary total knee arthroplasty achieves minimum inhibitory concentrations for common bacteria causing acute prosthetic joint infection.
  • Charles M Lawrie
  • Sally Jo
  • Toby Barrack
  • Stephen Roper
  • Rick W Wright
  • Ryan M Nunley
  • Robert L Barrack
  • Bone Joint J.2020 Jun;102-B(6_Supple_A):163-169. doi: 10.1302/0301-620X.102B6.BJJ-2019-1639.R1.

ロランサス・ミカランサス・ナノ粒子がストレプトゾトシン誘発性精巣機能障害を軽減した。ブドウ糖代謝酵素、酸化炎症ストレス、ステロイド生成酵素/タンパク質、Nrf2経路の関与

Loranthus micranthus nanoparticles abates streptozotocin-instigated testicular dysfunction in Wistar rats: Involvement of glucose metabolism enzymes, oxido-inflammatory stress, steroidogenic enzymes/protein and Nrf2 pathway.
  • Azubuike Peter Ebokaiwe
  • Sharon Osawe
  • Sharoon Griffin
  • Cornelia M Keck
  • Olasehinde Olusanya
  • Richard C Ehiri
  • Andrologia.2020 Jul;:e13749. doi: 10.1111/and.13749.Epub 2020-07-16.

乳糖発酵菌Salmonella enterica subsp. Enterica serovar 4,5:I:による消化管感染症の診断上の課題

Diagnostic challenge of gastrointestinal infection due to lactose-fermenting Salmonella enterica subsp. enterica serovar 4,5:I:.
  • Mathilde Payen
  • María Pardos de la Gándara
  • Aurélie Cointe
  • Alix Massiot
  • Philippe Bidet
  • François-Xavier Weill
  • Stéphane Bonacorsi
  • Diagn. Microbiol. Infect. Dis..2020 Jun;98(2):115105. S0732-8893(20)30482-X. doi: 10.1016/j.diagmicrobio.2020.115105.Epub 2020-06-10.

L858R耐性変異に対する強力なEGFR阻害剤としての硫化水素（HS）供与体と共役した4-アニリンキナゾリン誘導体の設計、合成および生物学的評価

Design, synthesis and biological evaluation of 4-aniline quinazoline derivatives conjugated with hydrogen sulfide (HS) donors as potent EGFR inhibitors against L858R resistance mutation.
  • You-Guang Zheng
  • Wu-Qi Zhang
  • Long Meng
  • Xiao-Qing Wu
  • Ling Zhang
  • Lin An
  • Cheng-Lin Li
  • Cai-Yun Gao
  • Liang Xu
  • Yi Liu
  • Eur J Med Chem.2020 Jun;202:112522. S0223-5234(20)30494-3. doi: 10.1016/j.ejmech.2020.112522.Epub 2020-06-27.

肝細胞におけるグルタミン酸シグナル伝達がアルコール性ステアトーシスを誘導する

Glutamate Signaling in Hepatic Stellate Cells Drives Alcoholic Steatosis.
  • Won-Mook Choi
  • Hee-Hoon Kim
  • Myung-Ho Kim
  • Resat Cinar
  • Hyon-Seung Yi
  • Hyuk Soo Eun
  • Seok-Hwan Kim
  • Young Jae Choi
  • Young-Sun Lee
  • So Yeon Kim
  • Wonhyo Seo
  • Jun-Hee Lee
  • Young-Ri Shim
  • Ye Eun Kim
  • Keungmo Yang
  • Tom Ryu
  • Jung Hwan Hwang
  • Chul-Ho Lee
  • Hueng-Sik Choi
  • Bin Gao
  • Won Kim
  • Sang Kyum Kim
  • George Kunos
  • Won-Il Jeong
  • Cell Metab..2019 11;30(5):877-889.e7. S1550-4131(19)30430-9. doi: 10.1016/j.cmet.2019.08.001.Epub 2019-08-29.

レビュー。外来、プライマリケア、コミュニティ、学校設定で提供される小児メンタルヘルスケアが救急科利用に与える影響-システマティックレビュー

Review: The impact of pediatric mental health care provided outpatient, primary care, community and school settings on emergency department use - a systematic review.
  • Scott W Kirkland
  • Amir Soleimani
  • Amanda S Newton
  • Child Adolesc Ment Health.2018 Feb;23(1):4-13. doi: 10.1111/camh.12230.Epub 2017-07-19.