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日本語AIでPubMedを検索

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日本語AIでPubMedを検索

PubMedの提供する医学論文データベースを日本語で検索できます。AI(Deep Learning)を活用した機械翻訳エンジンにより、精度高く日本語へ翻訳された論文をご参照いただけます。
対象期間    ～ 

2020年07月 みんなが読んでいる論文

COVID-19患者における死亡率に対する年齢の影響。611,583人の被験者を対象としたメタアナリシス

The Effect of Age on Mortality in Patients With COVID-19: A Meta-Analysis With 611,583 Subjects.
  • Clara Bonanad
  • Sergio García-Blas
  • Francisco Tarazona-Santabalbina
  • Juan Sanchis
  • Vicente Bertomeu-González
  • Lorenzo Fácila
  • Albert Ariza
  • Julio Núñez
  • Alberto Cordero
  • J Am Med Dir Assoc.2020 Jul;21(7):915-918. S1525-8610(20)30441-2. doi: 10.1016/j.jamda.2020.05.045.Epub 2020-05-25.

消防士の職業は、グレーターボストン地域の男性における喉頭扁平上皮がんおよび咽頭下咽頭扁平上皮がんのリスクの増加と関連している

Firefighter occupation is associated with increased risk for laryngeal and hypopharyngeal squamous cell carcinoma among men from the Greater Boston area.
  • Scott M Langevin
  • Melissa Eliot
  • Rondi A Butler
  • Michael McClean
  • Karl T Kelsey
  • Occup Environ Med.2020 06;77(6):381-385. oemed-2019-106271. doi: 10.1136/oemed-2019-106271.Epub 2020-02-27.

ゴンダル大学総合専門病院における抗レトロウイルス療法を受けている成人HIV患者におけるフォローアップ喪失の発生率と予測因子。競合リスク回帰モデリング

Incidence and predictors of loss to follow up among adult HIV patients on antiretroviral therapy in University of Gondar Comprehensive Specialized Hospital: A competing risk regression modeling.
  • Achamyeleh Birhanu Teshale
  • Adino Tesfahun Tsegaye
  • Haileab Fekadu Wolde
  • PLoS ONE.2020;15(1):e0227473. PONE-D-19-22281. doi: 10.1371/journal.pone.0227473.Epub 2020-01-24.

特発性炎症性ミオパチー患者における抗NXP2自己抗体の診断有用性、臨床表現型関連、および予後の重要性の評価：システマティックレビューおよびメタアナリシス

Assessment of diagnostic utility, clinical phenotypic associations, and prognostic significance of anti-NXP2 autoantibody in patients with idiopathic inflammatory myopathies: a systematic review and meta-analysis.
  • Liubing Li
  • Chenxi Liu
  • Linlin Cheng
  • Songxin Yan
  • Haizhen Chen
  • Yongzhe Li
  • Clin. Rheumatol..2020 Jul;10.1007/s10067-020-05291-1. doi: 10.1007/s10067-020-05291-1.Epub 2020-07-17.

肝虚血再灌流障害におけるグリコーゲン合成酵素キナーゼ3のN末端セリンリン酸化のアイソフォームと細胞型特異的な役割

Isoform- and Cell Type-Specific Roles of Glycogen Synthase Kinase 3 N-Terminal Serine Phosphorylation in Liver Ischemia Reperfusion Injury.
  • Ming Ni
  • Haoming Zhou
  • Jing Zhang
  • Dan Jin
  • Tianfei Lu
  • Ronald W Busuttil
  • Jerzy W Kupiec-Weglinski
  • Xuehao Wang
  • Yuan Zhai
  • J. Immunol..2020 Jul;ji2000397. doi: 10.4049/jimmunol.2000397.Epub 2020-07-17.

iPSC由来の網膜オルガノイドを用いたRP2網膜色素変性症のモデル化とレスキュー

Modeling and Rescue of RP2 Retinitis Pigmentosa Using iPSC-Derived Retinal Organoids.
  • Amelia Lane
  • Katarina Jovanovic
  • Ciara Shortall
  • Daniele Ottaviani
  • Anna Brugulat Panes
  • Nele Schwarz
  • Rosellina Guarascio
  • Matthew J Hayes
  • Arpad Palfi
  • Naomi Chadderton
  • G Jane Farrar
  • Alison J Hardcastle
  • Michael E Cheetham
  • Stem Cell Reports.2020 Jul;15(1):67-79. S2213-6711(20)30179-X. doi: 10.1016/j.stemcr.2020.05.007.Epub 2020-06-11.

喉頭下咽頭がん患者における原発性腫瘍の病期分類のための軟骨浸潤の検出におけるCTとMRIの診断性能の比較：システマティックレビューおよびメタアナリシス

Comparison of diagnostic performance between CT and MRI for detection of cartilage invasion for primary tumor staging in patients with laryngo-hypopharyngeal cancer: a systematic review and meta-analysis.
  • Se Jin Cho
  • Jeong Hyun Lee
  • Chong Hyun Suh
  • Jung Youn Kim
  • Donghyun Kim
  • Jung Bin Lee
  • Min Kyoung Lee
  • Sae Rom Chung
  • Young Jun Choi
  • Jung Hwan Baek
  • Eur Radiol.2020 Jul;30(7):3803-3812. 10.1007/s00330-020-06718-8. doi: 10.1007/s00330-020-06718-8.Epub 2020-03-09.

オキサリプラチン誘発性神経障害性疼痛を軽減する可能性のある鎮痛薬としてのブロムヘキシンとその活性代謝物であるアンブロキソールの比較-薬力学的および分子ドッキング試験-

Comparison of Bromhexine and its Active Metabolite - Ambroxol as Potential Analgesics Reducing Oxaliplatin-Induced Neuropathic Pain - Pharmacodynamic and Molecular Docking Studies.
  • Anna Furgała-Wojas
  • Magdalena Kowalska
  • Alicja Nowaczyk
  • Łukasz Fijałkowski
  • Kinga Sałat
  • Curr. Drug Metab..2020 Jul;CDM-EPUB-108069. doi: 10.2174/1389200221666200711155632.Epub 2020-07-11.

ルテニウム(II)をベースとした4-ニトロおよび4-アミノ-1,8-ナフタルイミド抱合体の合成、特性評価、および生物学的プロファイリングを行った

Synthesis, Characterization, and Biological Profiling of Ruthenium(II)-Based 4-Nitro- and 4-Amino-1,8-naphthalimide Conjugates.
  • Robert B P Elmes
  • Gary J Ryan
  • Maria Luisa Erby
  • Daniel O Frimannsson
  • Jonathan A Kitchen
  • Mark Lawler
  • D Clive Williams
  • Susan J Quinn
  • Thorfinnur Gunnlaugsson
  • Inorg Chem.2020 Jul;doi: 10.1021/acs.inorgchem.0c01395.Epub 2020-07-16.

乳酸菌で発酵させた牛乳由来のエクソ多糖類は、ヒトでは無作為化クロスオーバー試験で、ラットでは食事性カロテノイドのバイオアベイラビリティーを向上させている

Exopolysaccharides from milk fermented by lactic acid bacteria enhance dietary carotenoid bioavailability in humans in a randomized crossover trial and in rats.
  • Masashi Morifuji
  • Satomi Ichikawa
  • Masami Kitade
  • Tomoyuki Fukasawa
  • Yukio Asami
  • Yuki Manabe
  • Tatsuya Sugawara
  • Am. J. Clin. Nutr..2020 04;111(4):903-914. 5743410. doi: 10.1093/ajcn/nqaa020.

ビス-（μ-2,3,4,5-テトラフルオロ-ベンゾラト-κ(2)O:O')ビス-（1,10-フェナントロリン-κ(2)N:N')（2,3,4,5-テトラフルオロ-ベンゾラト-κO）銅(II)二水和物の結晶構造

Crystal structure of bis-(μ-2,3,4,5-tetra-fluoro-benzoato-κ(2) O:O')bis-[(1,10-phen-anthroline-κ(2) N:N')(2,3,4,5-tetra-fluoro-benzoato-κO)copper(II)] dihydrate.
  • Junshan Sun
  • Acta Crystallogr Sect E Struct Rep Online.2014 Nov;70(Pt 11):m365-6. wm5062. doi: 10.1107/S1600536814022065.Epub 2014-10-11.

テトラジンは、RhoA/ROCK1 シグナルの遮断を介して、一過性受容体電位カチオンチャネルプロテイン6の過剰発現によって誘発されたポッドサイトの損傷を抑制する

Tetrandrine Suppresses Transient Receptor Potential Cation Channel Protein 6 Overexpression- Induced Podocyte Damage via Blockage of RhoA/ROCK1 Signaling.
  • Jin Yu
  • Caifeng Zhu
  • Jiazhen Yin
  • Dongrong Yu
  • Feng Wan
  • Xuanli Tang
  • Xue Jiang
  • Drug Des Devel Ther.2020;14:361-370. 234262. doi: 10.2147/DDDT.S234262.Epub 2020-01-28.

粘土ナノチューブ上に形成されたRu/CdS量子ドットを可視光活性光触媒として利用し、S/Cd比とRu含有量の最適化を行った

Ru/CdS quantum dots templated on clay nanotubes as visible light active photocatalysts: optimization of S/Cd ratio and Ru content.
  • Anna V Stavitskaya
  • Ekaterina A Kozlova
  • Anna Yu Kurenkova
  • Aleksandr P Glotov
  • Dmitry S Selischev
  • Evgenii V Ivanov
  • Denis V Kozlov
  • Vladimir A Vinokurov
  • Rawil F Fakhrullin
  • Yuri M Lvov
  • Chemistry.2020 Jul;doi: 10.1002/chem.202002192.Epub 2020-07-08.

抽出されたDNAと核酸放出剤で処理されたサンプルを用いて、ヒトパピローマウイルス遺伝子型16および18を検出するための内部制御リコンビナーゼ支援増幅法（IC-RAA）アッセイ

Internally controlled recombinase-aided amplification (IC-RAA) assays for the detection of human papillomavirus genotypes 16 and 18 using extracted DNA and samples treated with nucleic acid releasing agent.
  • Jinrong Wang
  • Jianli Liu
  • Guowei Song
  • Zhi Cao
  • Jing Pan
  • Xinna Li
  • Yuan Gao
  • Juju Qi
  • Ziwei Chen
  • Guohao Fan
  • Xueding Bai
  • Ruiqing Zhang
  • Ruihuan Wang
  • Qingxia Duan
  • Lixin Li
  • Xinxin Shen
  • Xuejun Ma
  • Arch. Virol..2020 Jul;10.1007/s00705-020-04722-3. doi: 10.1007/s00705-020-04722-3.Epub 2020-07-17.

サルコペニアリスクを有する過体重・肥満高齢女性における変形性膝関節症に対するICFコアセットと連動した弾性抵抗運動の術後成績への効果：無作為化対照試験

Effects of Elastic Resistance Exercise on Postoperative Outcomes Linked to the ICF Core Sets for Osteoarthritis after Total Knee Replacement in Overweight and Obese Older Women with Sarcopenia Risk: A Randomized Controlled Trial.
  • Chun-De Liao
  • Yen-Shuo Chiu
  • Jan-Wen Ku
  • Shih-Wei Huang
  • Tsan-Hon Liou
  • J Clin Med.2020 Jul;9(7). E2194. doi: 10.3390/jcm9072194.Epub 2020-07-11.

ヒト単球におけるプロ炎症経路をダウンレギュレートするクルクミンとカプサイシンの主要標的を同定するためのシステム生物学的アプローチ

A systems biology approach to identify the key targets of curcumin and capsaicin that downregulate pro-inflammatory pathways in human monocytes.
  • Sharath Belenahalli Shekarappa
  • Shivananda Kandagalla
  • Vikas H Malojirao
  • Pavan Kumar G S
  • Prabhakar B T
  • Manjunatha Hanumanthappa
  • Comput Biol Chem.2019 Dec;83:107162. S1476-9271(19)30573-0. doi: 10.1016/j.compbiolchem.2019.107162.Epub 2019-11-09.

マンダリーナ・バイエルンを用いたドライホップビールの柑橘系果実味の強さを揮発性化合物の含有量に基づいて予測した

Prediction of Fruity-Citrus Intensity of Beers Dry Hopped with Mandarina Bavaria Based on the Content of Selected Volatile Compounds.
  • Júlio C Machado
  • Florian Lehnhardt
  • Zita E Martins
  • Hubert Kollmannsberger
  • Martina Gastl
  • Thomas Becker
  • Isabel M P L V O Ferreira
  • J. Agric. Food Chem..2020 Feb;68(7):2155-2163. doi: 10.1021/acs.jafc.9b06139.Epub 2020-02-07.

下痢で入院したアフリカの小児におけるクリプトスポリジウム（Cryptosporidiumspp.の迅速診断検査の性能

Performance of a rapid diagnostic test for the detection of Cryptosporidium spp. in African children admitted to hospital with diarrhea.
  • Gedéon Prince Manouana
  • Eva Lorenz
  • Mirabeau Mbong Ngwese
  • Paul Alvyn Nguema Moure
  • Oumou Maiga Ascofaré
  • Charity Wiafe Akenten
  • John Amuasi
  • Njari Rakotozandrindrainy
  • Raphael Rakotozandrindrainy
  • Joyce Mbwana
  • John Lusingu
  • Natalie Byrne
  • Sophia Melhem
  • Jeannot Frejus Zinsou
  • Roméo Bayodé Adegbite
  • Benedikt Hogan
  • Doris Winter
  • Jurgen May
  • Peter Gottfried Kremsner
  • Steffen Borrmann
  • Daniel Eibach
  • Ayola Akim Adegnika
  • PLoS Negl Trop Dis.2020 Jul;14(7):e0008448. PNTD-D-19-01374. doi: 10.1371/journal.pntd.0008448.Epub 2020-07-13.

セメントステムを使用した416例の再置換総膝関節形成術におけるバルス-バルグス拘束は、早期～中期レビューで低い後続再置換率で信頼性の高い再構築を提供する

Varus-valgus constraint in 416 revision total knee arthroplasties with cemented stems provides a reliable reconstruction with a low subsequent revision rate at early to mid-term review.
  • Afton K Limberg
  • Meagan E Tibbo
  • Mark W Pagnano
  • Kevin I Perry
  • Arlen D Hanssen
  • Matthew P Abdel
  • Bone Joint J.2020 Apr;102-B(4):458-462. doi: 10.1302/0301-620X.102B4.BJJ-2019-0719.R2.

高麗人参のギントンニン濃縮フラクションは、脂質代謝とブラウニングを制御するマウス白色脂肪細胞でのシグナル伝達経路を介してcAMP-タンパク質キナーゼを

The Gintonin-Enriched Fraction of Ginseng Regulates Lipid Metabolism and Browning via the cAMP-Protein Kinase a Signaling Pathway in Mice White Adipocytes.
  • Kippeum Lee
  • Heegu Jin
  • Sungwoo Chei
  • Hyun-Ji Oh
  • Sun-Hye Choi
  • Seung-Yeol Nah
  • Boo-Yong Lee
  • Biomolecules.2020 Jul;10(7). E1048. doi: 10.3390/biom10071048.Epub 2020-07-15.

脂肪細胞脂肪酸結合タンパク質の血清レベルは、2型糖尿病患者の急速な腎機能低下と関連しており、腎機能は保存されています

Serum Levels of Adipocyte Fatty Acid-Binding Protein Are Associated with Rapid Renal Function Decline in Patients with Type 2 Diabetes Mellitus and Preserved Renal Function.
  • Da Hea Seo
  • Moonsuk Nam
  • Mihye Jung
  • Young Ju Suh
  • Seong Hee Ahn
  • Seongbin Hong
  • So Hun Kim
  • Diabetes Metab J.2020 Jul;44.e37. doi: 10.4093/dmj.2019.0221.Epub 2020-07-10.

頭蓋内動脈瘤における出血：有病率と一般的特徴

Blebs in intracranial aneurysms: prevalence and general characteristics.
  • Seyedeh Fatemeh Salimi Ashkezari
  • Felicitas J Detmer
  • Fernando Mut
  • Bong Jae Chung
  • Alexander K Yu
  • Christopher J Stapleton
  • Alfred P See
  • Sepideh Amin-Hanjani
  • Fady T Charbel
  • Behnam Rezai Jahromi
  • Mika Niemelä
  • Juhana Frösen
  • Ji Zhou
  • Spandan Maiti
  • Anne M Robertson
  • Juan R Cebral
  • J Neurointerv Surg.2020 Jul;neurintsurg-2020-016274. doi: 10.1136/neurintsurg-2020-016274.Epub 2020-07-17.

COVID-19発生時の2019年新型コロナウイルス（SARS-CoV-2）感染症の診断における血清学的検査の評価

Evaluations of the serological test in the diagnosis of 2019 novel coronavirus (SARS-CoV-2) infections during the COVID-19 outbreak.
  • Dachuan Lin
  • Lei Liu
  • Mingxia Zhang
  • Yunlong Hu
  • Qianting Yang
  • Jiubiao Guo
  • Youchao Dai
  • Yuzhong Xu
  • Yi Cai
  • Xinchun Chen
  • Kaisong Huang
  • Zheng Zhang
  • Eur. J. Clin. Microbiol. Infect. Dis..2020 Jul;10.1007/s10096-020-03978-6. doi: 10.1007/s10096-020-03978-6.Epub 2020-07-17.

変異型GISTの腹部再発患者におけるファーストラインのregorafenibに対する完全な放射線学的反応

Complete radiological response to first-line regorafenib in a patient with abdominal relapse of mutated GIST.
  • Margherita Nannini
  • Di Scioscio Valerio
  • Elisa Gruppioni
  • Annalisa Altimari
  • Benedetta Chiusole
  • Maristella Saponara
  • Maria Abbondanza Pantaleo
  • Antonella Brunello
  • Therap Adv Gastroenterol.2020;13:1756284820927305. 10.1177_1756284820927305. doi: 10.1177/1756284820927305.Epub 2020-06-30.

早期乳癌に対する乳房温存療法は、乳房切除術と比較して生存率の改善と関連している。全米がんデータベースを用いた傾向スコアマッチド比較

Breast-Conserving Therapy is Associated with Improved Survival Compared with Mastectomy for Early-Stage Breast Cancer: A Propensity Score Matched Comparison Using the National Cancer Database.
  • Erica Wrubel
  • Raylene Natwick
  • G Paul Wright
  • Ann. Surg. Oncol..2020 Jul;10.1245/s10434-020-08829-4. doi: 10.1245/s10434-020-08829-4.Epub 2020-07-13.

SLC22A12（URAT1）遺伝子のヘテロ接合性変異を有する腎移植で腎性低酸血症を発症した症例

Transplantation of a kidney with a heterozygous mutation in the SLC22A12 (URAT1) gene causing renal hypouricemia: a case report.
  • Kiyokazu Tsuji
  • Mineaki Kitamura
  • Kumiko Muta
  • Yasushi Mochizuki
  • Takayasu Mori
  • Eisei Sohara
  • Shinichi Uchida
  • Hideki Sakai
  • Hiroshi Mukae
  • Tomoya Nishino
  • BMC Nephrol.2020 Jul;21(1):282. 10.1186/s12882-020-01940-4. doi: 10.1186/s12882-020-01940-4.Epub 2020-07-16.

SLC12A2 変異体は神経発達障害や蝸牛の障害を引き起こす

SLC12A2 variants cause a neurodevelopmental disorder or cochleovestibular defect.
  • Alisdair McNeill
  • Emanuela Iovino
  • Luke Mansard
  • Christel Vache
  • David Baux
  • Emma Bedoukian
  • Helen Cox
  • John Dean
  • David Goudie
  • Ajith Kumar
  • Ruth Newbury-Ecob
  • Chiara Fallerini
  • Alessandra Renieri
  • Diego Lopergolo
  • Francesca Mari
  • Catherine Blanchet
  • Marjolaine Willems
  • Anne-Francoise Roux
  • Tommaso Pippucci
  • Eric Delpire
  • Brain.2020 Jul;awaa176. doi: 10.1093/brain/awaa176.Epub 2020-07-13.

カナダの放射線治療医と英国の治療用放射線技師の、放射線治療中の患者を固定するための安全ストラップの経験と意見を評価する

Evaluating Canadian Radiation Therapists and UK Therapeutic Radiographers' Experiences and Opinions of a Safety Strap to Secure Patients during Radiotherapy.
  • Annabelle Judge
  • Carina Feuz
  • David Evans
  • Nicholas Courtier
  • J Med Imaging Radiat Sci.2020 Jul;S1939-8654(20)30137-5. doi: 10.1016/j.jmir.2020.05.006.Epub 2020-07-14.

デュアルメカニズムによる光線力学的治療を強化した活性酸素応答性ナノメディシン。GSH枯渇と生合成阻害の2つのメカニズムで光線力学的治療を強化した活性酸素応答性ナノメディシンを開発した

A ROS responsive nanomedicine with enhanced photodynamic therapy via dual mechanisms: GSH depletion and biosynthesis inhibition.
  • Jinhui Hu
  • Ting Wang
  • Lin Zhou
  • Shaohua Wei
  • J. Photochem. Photobiol. B, Biol..2020 Jul;209:111955. S1011-1344(20)30405-X. doi: 10.1016/j.jphotobiol.2020.111955.Epub 2020-07-05.

エピジェネティックな移行を受けたがん細胞は短期的な抵抗性を示し、薬物治療により中期的な抵抗性を持つ細胞に変化する

Cancer cells undergoing epigenetic transition show short-term resistance and are transformed into cells with medium-term resistance by drug treatment.
  • Shiv Poojan
  • Seung-Hyun Bae
  • Jae-Woong Min
  • Eun Young Lee
  • Yura Song
  • Hee Yeon Kim
  • Hye Won Sim
  • Eun-Kyung Kang
  • Young-Ho Kim
  • Hae-Ock Lee
  • Yourae Hong
  • Woong-Yang Park
  • Hyonchol Jang
  • Kyeong-Man Hong
  • Exp. Mol. Med..2020 Jul;10.1038/s12276-020-0464-3. doi: 10.1038/s12276-020-0464-3.Epub 2020-07-13.

南米のウシトリパノソーマ症の流行地であるブラジルパンタナールの肉牛におけるヘモプラズマの発生と遺伝的多様性

Occurrence and genetic diversity of hemoplasmas in beef cattle from the Brazilian Pantanal, an endemic area for bovine trypanosomiasis in South America.
  • Victória Valente Califre de Mello
  • Inalda Angélica de Souza Ramos
  • Heitor Miraglia Herrera
  • Natalia Serra Mendes
  • Ana Cláudia Calchi
  • João Bosco Vilela Campos
  • Gabriel Carvalho Macedo
  • João Vitor Almeida Alves
  • Rosangela Zacarias Machado
  • Marcos Rogério André
  • Comp. Immunol. Microbiol. Infect. Dis..2019 Oct;66:101337. S0147-9571(19)30134-1. doi: 10.1016/j.cimid.2019.101337.Epub 2019-07-24.

YYFZBJSは、腸内細菌叢のリモデリングと調節性T細胞の生成を阻害することにより、Apcマウスの大腸がんの進行を改善する

YYFZBJS ameliorates colorectal cancer progression in Apc mice by remodeling gut microbiota and inhibiting regulatory T-cell generation.
  • Hua Sui
  • Lu Zhang
  • Kaijuan Gu
  • Ni Chai
  • Qing Ji
  • Lihong Zhou
  • Yan Wang
  • Junze Ren
  • Limei Yang
  • Bimeng Zhang
  • Jing Hu
  • Qi Li
  • Cell Commun. Signal.2020 Jul;18(1):113. 10.1186/s12964-020-00596-9. doi: 10.1186/s12964-020-00596-9.Epub 2020-07-16.

新規免疫法により作製されたパン特異的抗血清は、神経毒性のあるヘビ毒に対して高い中和スペクトルを示した

A pan-specific antiserum produced by a novel immunization strategy shows a high spectrum of neutralization against neurotoxic snake venoms.
  • Kavi Ratanabanangkoon
  • Kae Yi Tan
  • Kritsada Pruksaphon
  • Chaiya Klinpayom
  • José María Gutiérrez
  • Naeem H Quraishi
  • Choo Hock Tan
  • Sci Rep.2020 Jul;10(1):11261. 10.1038/s41598-020-66657-8. doi: 10.1038/s41598-020-66657-8.Epub 2020-07-09.

下部尿管結石に対する医療的圧迫療法としてのタムスロシン＋タダラフィル対タムスロシンの有効性。無作為化対照試験

Efficacy of Tamsulosin plus Tadalafil versus Tamsulosin as Medical Expulsive Therapy for Lower Ureteric Stones: A Randomized Controlled Trial.
  • Diwas Gnyawali
  • Manish Man Pradhan
  • Prem Raj Sigdel
  • Purushottam Parajuli
  • Sampanna Chudal
  • Sujeet Poudyal
  • Suman Chapagain
  • Bhoj Raj Luitel
  • Pawan Raj Chalise
  • Uttam Sharma
  • Prem Raj Gyawali
  • Adv Urol.2020;2020:4347598. doi: 10.1155/2020/4347598.Epub 2020-01-29.

ヒトサイトメガロウイルス糖タンパク質Bの融合活性型によって誘導される細胞融合は、gBのエクトドメイン内のAD-5に向けられた抗体によって阻害される

Cell fusion induced by a fusion-active form of human cytomegalovirus glycoprotein B is inhibited by antibodies directed at AD-5 in the ectodomain of gB.
  • Nina Reuter
  • Barbara Kropff
  • Julia K Schneiderbanger
  • Mira Alt
  • Adalbert Krawczyk
  • Christian Sinzger
  • Thomas H Winkler
  • William J Britt
  • Michael Mach
  • Marco Thomas
  • J. Virol..2020 Jul;JVI.01276-20. doi: 10.1128/JVI.01276-20.Epub 2020-07-08.

2031年の都市計画と交通計画のシナリオが、大都市圏の自動車利用とアクティブ交通に与える潜在的な影響

The Potential Impacts of Urban and Transit Planning Scenarios for 2031 on Car Use and Active Transportation in a Metropolitan Area.
  • Patrick Morency
  • Céline Plante
  • Anne-Sophie Dubé
  • Sophie Goudreau
  • Catherine Morency
  • Pierre-Léo Bourbonnais
  • Naveen Eluru
  • Louis-François Tétreault
  • Marianne Hatzopoulou
  • Naveen Chandra Iraganaboina
  • Tanmoy Bhowmik
  • Audrey Smargiassi
  • Int J Environ Res Public Health.2020 Jul;17(14). E5061. doi: 10.3390/ijerph17145061.Epub 2020-07-14.

新規に合成したシアノベンジルリデンキサンテン類の銅/水酸化ナトリウム界面での吸着挙動と腐食防止特性電気化学的,X線光電子分光法及び理論的研究を行った

Adsorption behavior and corrosion inhibitive characteristics of newly synthesized cyano-benzylidene xanthenes on copper/sodium hydroxide interface: Electrochemical, X-ray photoelectron spectroscopy and theoretical studies.
  • Mohamed E Khalifa
  • Islam H El Azab
  • Adil A Gobouri
  • Gaber A M Mersal
  • Sarah Alharthi
  • Murat Saracoglu
  • Fatma Kandemirli
  • Jacek Ryl
  • Mohammed A Amin
  • J Colloid Interface Sci.2020 Jul;580:108-125. S0021-9797(20)30855-9. doi: 10.1016/j.jcis.2020.06.110.Epub 2020-07-02.

未治療の転移性腎細胞がんおよび肉腫性特徴を有する患者に対するアテゾリズマブ＋ベバシズマブとスニチニブの比較。IMmotion151臨床試験の事前指定サブグループ解析

Atezolizumab plus Bevacizumab Versus Sunitinib for Patients with Untreated Metastatic Renal Cell Carcinoma and Sarcomatoid Features: A Prespecified Subgroup Analysis of the IMmotion151 Clinical Trial.
  • Brian I Rini
  • Robert J Motzer
  • Thomas Powles
  • David F McDermott
  • Bernard Escudier
  • Frede Donskov
  • Robert Hawkins
  • Sergio Bracarda
  • Jens Bedke
  • Ugo De Giorgi
  • Camillo Porta
  • Alain Ravaud
  • Francis Parnis
  • Enrique Grande
  • Wei Zhang
  • Mahrukh Huseni
  • Susheela Carroll
  • Roxana Sufan
  • Christina Schiff
  • Michael B Atkins
  • Eur. Urol..2020 Jul;S0302-2838(20)30450-4. doi: 10.1016/j.eururo.2020.06.021.Epub 2020-07-09.

異なる胚由来のヒト骨格筋における10個のサルコメリックMyHCアイソフォームの発現と同定。哺乳類における多様性と類似性

Expression and identification of 10 sarcomeric MyHC isoforms in human skeletal muscles of different embryological origin. Diversity and similarity in mammalian species.
  • Francesco Mascarello
  • Luana Toniolo
  • Pasqua Cancellara
  • Carlo Reggiani
  • Lisa Maccatrozzo
  • Ann. Anat..2016 Sep;207:9-20. S0940-9602(16)30029-2. doi: 10.1016/j.aanat.2016.02.007.Epub 2016-03-09.

ネコのAB型血液群システムに関連するシチジン一リン酸-N-アセチルノイラミン酸ヒドロキシラーゼ（CMAH）遺伝子の分子解析

Molecular Characterization of the Cytidine Monophosphate-N-Acetylneuraminic Acid Hydroxylase (CMAH) Gene Associated with the Feline AB Blood Group System.
  • Toshinori Omi
  • Shota Nakazawa
  • Chihiro Udagawa
  • Naomi Tada
  • Kazuhiko Ochiai
  • Yong Hwa Chong
  • Yuiko Kato
  • Hiroko Mitsui
  • Azusa Gin
  • Hitomi Oda
  • Daigo Azakami
  • Kyoichi Tamura
  • Toshinori Sako
  • Takeshi Inagaki
  • Atsushi Sakamoto
  • Toshihiko Tsutsui
  • Makoto Bonkobara
  • Shuichi Tsuchida
  • Shigenori Ikemoto
  • PLoS ONE.2016;11(10):e0165000. PONE-D-16-31188. doi: 10.1371/journal.pone.0165000.Epub 2016-10-18.

米国南カリフォルニア沿岸のBrandt's cormorants ()が関与するエピゾート感染に伴う原虫性脳炎とその間に発生した原虫性脳炎

Protozoal encephalitis associated with and during an epizootic involving Brandt's cormorants () in coastal Southern California, USA.
  • Ozge Erdogan Bamac
  • Krysta H Rogers
  • David Arranz-Solís
  • Jeroen P J Saeij
  • Stephany Lewis
  • Rebecca Duerr
  • Julie Skoglund
  • Lisa Peronne
  • Aslı Mete
  • Int J Parasitol Parasites Wildl.2020 Aug;12:185-191. S2213-2244(20)30059-6. doi: 10.1016/j.ijppaw.2020.06.005.Epub 2020-06-13.

腫瘍開始細胞を標的とした薬剤は、手術後、化学療法後の卵巣癌再発モデルにおける生存期間を延長する

Drugs Targeting Tumor-Initiating Cells Prolong Survival in a Post-Surgery, Post-Chemotherapy Ovarian Cancer Relapse Model.
  • Brittney S Harrington
  • Michelle K Ozaki
  • Michael W Caminear
  • Lidia F Hernandez
  • Elizabeth Jordan
  • Nicholas J Kalinowski
  • Ian S Goldlust
  • Rajarshi Guha
  • Marc Ferrer
  • Craig Thomas
  • Jyoti Shetty
  • Bao Tran
  • Nathan Wong
  • Carrie D House
  • Christina M Annunziata
  • Cancers (Basel).2020 Jun;12(6). E1645. doi: 10.3390/cancers12061645.Epub 2020-06-21.

イソプロテレノールによる心毒性に対するタンゲレチンの心保護効果の背景には、ラットモデルにおけるPI3K/Aktシグナル伝達経路の調節を介している可能性がある

A possible underlying mechanism behind the cardioprotective efficacy of tangeretin on isoproterenol triggered cardiotoxicity via modulating PI3K/Akt signaling pathway in a rat model.
  • Ermiao Zhang
  • Hailing Yang
  • Min Li
  • Mei Ding
  • J. Food Biochem..2020 Jul;:e13368. doi: 10.1111/jfbc.13368.Epub 2020-07-09.

高リスク進行胃癌に対するネオアジュバント化学療法＋手術：KDOG1001試験の長期成績

Neoadjuvant chemotherapy plus surgery for high-risk advanced gastric cancer: long-term results of KDOG1001 trial.
  • Kei Hosoda
  • Chikatoshi Katada
  • Kenji Ishido
  • Masahiro Niihara
  • Hideki Ushiku
  • Mikiko Sakuraya
  • Marie Washio
  • Takuya Wada
  • Akinori Watanabe
  • Hiroki Harada
  • Takeo Sato
  • Hiroshi Tajima
  • Takashi Kaizu
  • Yoshimasa Kosaka
  • Hiroshi Kato
  • Norihiko Sengoku
  • Kiyoshi Tanaka
  • Takeshi Naito
  • Yusuke Kumamoto
  • Takafumi Sangai
  • Satoshi Tanabe
  • Wasaburo Koizumi
  • Keishi Yamashita
  • Naoki Hiki
  • Langenbecks Arch Surg.2020 Jul;10.1007/s00423-020-01924-w. doi: 10.1007/s00423-020-01924-w.Epub 2020-07-02.

コンゴ民主共和国の小児の対になった血液サンプルと便サンプルから分離された非伝染性サルモネラの間に高い遺伝的類似性が認められた

High genetic similarity between non-typhoidal Salmonella isolated from paired blood and stool samples of children in the Democratic Republic of the Congo.
  • Marie-France Phoba
  • Barbara Barbé
  • Benedikt Ley
  • Sandra Van Puyvelde
  • Annelies Post
  • Wesley Mattheus
  • Stijn Deborggraeve
  • Octavie Lunguya
  • Jan Jacobs
  • PLoS Negl Trop Dis.2020 Jul;14(7):e0008377. PNTD-D-20-00088. doi: 10.1371/journal.pntd.0008377.Epub 2020-07-02.

一次および再置換術の膝関節形成術の予測量は、今後30年の間に将来のヘルスケアシステムに計り知れない負担をかけることになります

The projected volume of primary and revision total knee arthroplasty will place an immense burden on future heath care systems over the next 30 years.
  • Alexander Klug
  • Yves Gramlich
  • Maximilian Rudert
  • Philipp Drees
  • Reinhard Hoffmann
  • Manuel Weißenberger
  • Karl Philipp Kutzner
  • Knee Surg Sports Traumatol Arthrosc.2020 Jul;10.1007/s00167-020-06154-7. doi: 10.1007/s00167-020-06154-7.Epub 2020-07-15.

小児患者における化学療法または放射線療法後の二次性腎新生物

Secondary Renal Neoplasia Following Chemotherapy or Radiation in Pediatric Patients.
  • Sounak Gupta
  • Chad M Vanderbilt
  • Bradley C Leibovich
  • Loren Herrera-Hernandez
  • Aditya Raghunathan
  • William R Sukov
  • Jesse S Voss
  • Emily G Barr Fritcher
  • Katelyn A Reed
  • Christine M Lohse
  • Victor E Reuter
  • Rafael E Jimenez
  • R Houston Thompson
  • John C Cheville
  • Hum. Pathol..2020 Jul;S0046-8177(20)30137-4. doi: 10.1016/j.humpath.2020.07.014.Epub 2020-07-15.

運動トレーニングはアルツハイマー病モデルの脳血管機能障害を改善する：P2Y2受容体と小胞体ストレスの役割

Exercise training ameliorates cerebrovascular dysfunction in a murine model of Alzheimer's disease: role of the P2Y2 receptor and endoplasmic reticulum stress.
  • Junyoung Hong
  • Soon-Gook Hong
  • Jonghae Lee
  • Joon-Young Park
  • Jason L Eriksen
  • Bridgette V Rooney
  • Yoonjung Park
  • Am. J. Physiol. Heart Circ. Physiol..2020 06;318(6):H1559-H1569. doi: 10.1152/ajpheart.00129.2020.Epub 2020-05-08.

子宮内膜症関連疼痛を有する女性を対象とした第3相試験における臨床効果評価項目に対するエラゴリックス曝露の効果。マルコフモデルの応用

Effect of elagolix exposure on clinical efficacy endpoints in phase 3 trials in women with endometriosis-associated pain: An application of Markov model.
  • Insa Winzenborg
  • Akshanth R Polepally
  • Ahmed Nader
  • Nael M Mostafa
  • Peter Noertersheuser
  • Juki Ng
  • CPT Pharmacometrics Syst Pharmacol.2020 Jul;doi: 10.1002/psp4.12545.Epub 2020-07-03.

脳虚血時にはHIF1α/ZEB2軸を介してTRPC6が糸球体ポッドサイトに誘導され、蛋白尿に寄与している

Cerebral ischemia induces TRPC6 via HIF1α/ZEB2 axis in the glomerular podocytes and contributes to proteinuria.
  • Krishnamurthy Nakuluri
  • Rajkishor Nishad
  • Dhanunjay Mukhi
  • Sireesh Kumar
  • Venkata P Nakka
  • Lakshmi P Kolligundla
  • Parimala Narne
  • Sai Sampath K Natuva
  • Prakash Babu Phanithi
  • Anil K Pasupulati
  • Sci Rep.2019 11;9(1):17897. 10.1038/s41598-019-52872-5. doi: 10.1038/s41598-019-52872-5.Epub 2019-11-29.

ロングノンコーディングRNA366.2は、ヒツジ子宮内膜上皮細胞の増殖・遊走をmiR-1576のceRNAとしてWNT6をアップレギュレーションすることで制御している

Long non-coding RNA366.2 controls endometrial epithelial cell proliferation and migration by upregulating WNT6 as a ceRNA of miR-1576 in sheep uterus.
  • Xiaoxiao Gao
  • Xiaolei Yao
  • Zhibo Wang
  • Xiaohe Li
  • Xiaodan Li
  • Shiyu An
  • Zongyou Wei
  • Guomin Zhang
  • Feng Wang
  • Biochim Biophys Acta Gene Regul Mech.2020 Jul;:194606. S1874-9399(20)30189-9. doi: 10.1016/j.bbagrm.2020.194606.Epub 2020-07-14.

患者の血液管理プログラム内での術前エリスロポエチン投与は、輸血と術後貧血の両方を減少させる：プロスペクティブ観察研究

Preoperative erythropoietin within a patient blood management program decreases both blood transfusion and postoperative anemia: a prospective observational study.
  • Philippe Biboulet
  • Caroline Motais
  • Mathieu Pencole
  • Oliver Karam
  • Gaëtan Dangelser
  • Pierre Smilevitch
  • Guillaume Maissiat
  • Xavier Capdevila
  • Sophie Bringuier
  • Transfusion.2020 Jul;doi: 10.1111/trf.15900.Epub 2020-07-18.

iFRはCTOにおける深部にあるが大部分は可逆性の虚血を発見し、PCIの結果を最適化するのに役立つ

iFR uncovers profound but mostly reversible ischemia in CTOs and helps to optimize PCI results.
  • Peter Kayaert
  • Mathieu Coeman
  • Benny Drieghe
  • Johan Bennett
  • Keir McCutcheon
  • Jo Dens
  • Claudiu Ungureanu
  • Carlo Zivelonghi
  • Pierfrancesco Agostoni
  • Yoann Bataille
  • Quentin de Hemptinne
  • Sofie Gevaert
  • Michel De Pauw
  • Steven Haine
  • Catheter Cardiovasc Interv.2020 Jun;doi: 10.1002/ccd.29072.Epub 2020-06-17.

上眼窩気道装置を用いたレミフェンタニルベースの全身麻酔時におけるデスフルラン、セボフルラン、プロポフォールの眼窩開口部に対する効果の比較

Comparison of the Effects of Desflurane, Sevoflurane, and Propofol on the Glottic Opening Area during Remifentanil-Based General Anesthesia Using a Supraglottic Airway Device.
  • Takashi Kondo
  • Hiromichi Izumi
  • Makiko Kitagawa
  • Anesthesiol Res Pract.2020;2020:1302898. doi: 10.1155/2020/1302898.Epub 2020-06-19.

ミトコンドリア機能不全は骨形成を阻害し、破骨細胞の活性を高め、加齢に伴う骨量減少を促進する

Mitochondrial dysfunction impairs osteogenesis, increases osteoclast activity, and accelerates age related bone loss.
  • Philip F Dobson
  • Ella P Dennis
  • Daniel Hipps
  • Amy Reeve
  • Alex Laude
  • Carla Bradshaw
  • Craig Stamp
  • Anna Smith
  • David J Deehan
  • Doug M Turnbull
  • Laura C Greaves
  • Sci Rep.2020 Jul;10(1):11643. 10.1038/s41598-020-68566-2. doi: 10.1038/s41598-020-68566-2.Epub 2020-07-15.

思春期の青少年における運動トレーニング後の単純な体重変化を超えたインスリン感受性の変化を予測する際の心肺体力、内臓脂肪、肝脂肪の有用性の評価

Assessing the utility of cardiorespiratory fitness, visceral fat and liver fat in predicting changes in insulin sensitivity beyond simple changes in body weight after exercise training in adolescents.
  • Jennifer L Kuk
  • SoJung Lee
  • Appl Physiol Nutr Metab.2020 Jul;doi: 10.1139/apnm-2020-0284.Epub 2020-07-16.

マラウイのリロングウェにおける電子小児救急・急性期医療データベースの開発と実施から得られた教訓

Lessons learned from the development and implementation of an electronic paediatric emergency and acute care database in Lilongwe, Malawi.
  • Emily J Ciccone
  • Alyssa E Tilly
  • Msandeni Chiume
  • Yamikani Mgusha
  • Michelle Eckerle
  • Howard Namuku
  • Heather L Crouse
  • Treasure B Mkaliainga
  • Jeff A Robison
  • Charles J Schubert
  • Tisungane Mvalo
  • Elizabeth Fitzgerald
  • BMJ Glob Health.2020 Jul;5(7). e002410. doi: 10.1136/bmjgh-2020-002410.

小規模腎塊サーベイランス。生検で特徴づけられたコホートにおける組織学的に特異的な成長率

Small Renal Mass Surveillance: Histology-specific Growth Rates in a Biopsy-characterized Cohort.
  • Antonio Finelli
  • Douglas C Cheung
  • Ashraf Al-Matar
  • Andrew J Evans
  • Christopher G Morash
  • Stephen E Pautler
  • D Robert Siemens
  • Simon Tanguay
  • Ricardo A Rendon
  • Martin E Gleave
  • Darrel E Drachenberg
  • Joseph L Chin
  • Neil E Fleshner
  • Masoom A Haider
  • John R Kachura
  • Jenna Sykes
  • Michael A S Jewett
  • Eur. Urol..2020 Jul;S0302-2838(20)30513-3. doi: 10.1016/j.eururo.2020.06.053.Epub 2020-07-14.

全インド眼科学会-インド眼輪形成術協会 COVID-19 パンデミック時の眼輪形成術および涙腺外科手術における好ましい実施方法に関するコンセンサス声明

All India Ophthalmological Society - Oculoplastics Association of India consensus statement on preferred practices in oculoplasty and lacrimal surgery during the COVID-19 pandemic.
  • Mohammad Javed Ali
  • Raghuraj Hegde
  • Akshay Gopinathan Nair
  • Mandeep S Bajaj
  • Subhash M Betharia
  • Kasturi Bhattacharjee
  • Apjit K Chhabra
  • Jayanta K Das
  • Gagan Dudeja
  • Ashok K Grover
  • Santosh G Honavar
  • Usha Kim
  • Lakshmi Mahesh
  • Bipasha Mukherjee
  • Anita Sethi
  • Mukesh Sharma
  • Usha Singh
  • Indian J Ophthalmol.2020 06;68(6):974-980. IndianJOphthalmol_2020_68_6_974_284779. doi: 10.4103/ijo.IJO_1415_20.

嚢胞性線維症に対する抗菌薬スチュワードシップの関連性の発見

Finding the relevance of antimicrobial stewardship for cystic fibrosis.
  • Jonathan D Cogen
  • Barbara C Kahl
  • Holly Maples
  • Susanna A McColley
  • Jason A Roberts
  • Kevin L Winthrop
  • Andrew M Morris
  • Alison Holmes
  • Patrick A Flume
  • Donald R VanDevanter
  • Valerie Waters
  • Marianne S Muhlebach
  • J Stuart Elborn
  • Lisa Saiman
  • Scott C Bell
  • J. Cyst. Fibros..2020 Jul;19(4):511-520. S1569-1993(20)30059-X. doi: 10.1016/j.jcf.2020.02.012.Epub 2020-02-29.

ブラジルの小児固形腫瘍患者コホートにおけるTP53 p.R337H突然変異の頻度

Frequency of the TP53 p.R337H mutation in a Brazilian cohort of pediatric patients with solid tumors.
  • José Antonio da Silva Feitosa
  • Pablo Ferreira das Chagas
  • Graziella Ribeiro de Sousa
  • Rosane Gomes de Paula Queiroz
  • Gustavo Alencastro Veiga Cruzeiro
  • Luiz Gonzaga Tone
  • Kleiton Silva Borges
  • Elvis Terci Valera
  • Mol. Biol. Rep..2020 Jul;10.1007/s11033-020-05655-5. doi: 10.1007/s11033-020-05655-5.Epub 2020-07-15.

HIV神経障害性疼痛に対する薬理学的および非薬理学的介入。システマティックレビューとメタアナリシス

Pharmacologic and Non-Pharmacologic Interventions for HIV-Neuropathy Pain. A Systematic Review and a Meta-Analysis.
  • Aikaterini Amaniti
  • Chrysanthi Sardeli
  • Varvara Fyntanidou
  • Panagiota Papakonstantinou
  • Ioannis Dalakakis
  • Antonios Mylonas
  • Konstantinos Sapalidis
  • Christoforos Kosmidis
  • Athanasios Katsaounis
  • Dimitrios Giannakidis
  • Charilaos Koulouris
  • Zoi Aidoni
  • Nikolaos Michalopoulos
  • Paul Zarogoulidis
  • Isaak Kesisoglou
  • Aris Ioannidis
  • Anastasios Vagionas
  • Konstantinos Romanidis
  • Panagoula Oikonomou
  • Vasilios Grosomanidis
  • Medicina (Kaunas).2019 Nov;55(12). E762. doi: 10.3390/medicina55120762.Epub 2019-11-28.

脂肪組織は（合成）カンナビノイドの検出に適しているか？JWH-210、RCS-4、∆9-テトラヒドロカンナビノールを豚に肺投与した後の死前および死後の検体を分析した比較研究

Is adipose tissue suitable for detection of (synthetic) cannabinoids? A comparative study analyzing antemortem and postmortem specimens following pulmonary administration of JWH-210, RCS-4, as well as ∆9-tetrahydrocannabinol to pigs.
  • Nadine Schaefer
  • Frederike Nordmeier
  • Ann-Katrin Kröll
  • Christina Körbel
  • Matthias W Laschke
  • Michael D Menger
  • Hans H Maurer
  • Markus R Meyer
  • Peter H Schmidt
  • Arch. Toxicol..2020 Jul;10.1007/s00204-020-02843-x. doi: 10.1007/s00204-020-02843-x.Epub 2020-07-14.

術後CTにおける感染腹水コレクションと無菌腹水コレクション：臨床所見と画像所見に基づくスコアリングシステム

Infected versus sterile abdominal fluid collections in postoperative CT: a scoring system based on clinical and imaging findings.
  • Christoph G Radosa
  • Julia C Radosa
  • Michael Laniado
  • Julia Brandt
  • Johannes Streitzig
  • Danilo Seppelt
  • Andreas Volk
  • Verena Plodeck
  • Jens P Kühn
  • Ralf-Thorsten Hoffmann
  • Abdom Radiol (NY).2020 Jul;10.1007/s00261-020-02635-y. doi: 10.1007/s00261-020-02635-y.Epub 2020-07-16.

単純な虫垂炎に対する腹腔鏡下虫垂切除術後の術後抗生物質の静脈内投与は必要か？A Prospective Double-blinded Randomized Controlled Trial

Are Postoperative Intravenous Antibiotics Indicated After Laparoscopic Appendicectomy for Simple Appendicitis? A Prospective Double-blinded Randomized Controlled Trial.
  • Nicole Mennie
  • Gayathri Panabokke
  • Annette Chang
  • Sharman Tan Tanny
  • Wei Cheng
  • Maurizio Pacilli
  • Peter Ferguson
  • Ramesh M Nataraja
  • Ann. Surg..2020 Aug;272(2):248-252. 00000658-202008000-00057. doi: 10.1097/SLA.0000000000003732.

多発性骨髄腫の治療における免疫療法に関するがん免疫療法学会のコンセンサス声明

The Society for Immunotherapy of Cancer consensus statement on immunotherapy for the treatment of multiple myeloma.
  • Nina Shah
  • Jack Aiello
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  • Ivan M Borrello
  • Ajai Chari
  • Adam D Cohen
  • Karthik Ganapathi
  • Lissa Gray
  • Damian Green
  • Amrita Krishnan
  • Yi Lin
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イオン性およびナノ酸化亜鉛暴露に対する河川バイオフィルムコミュニティの応答に関するメタトランスクリプトームの洞察

Metatranscriptomic Insights Into the Response of River Biofilm Communities to Ionic and Nano-Zinc Oxide Exposures.
  • Jordyn Bergsveinson
  • Julie Roy
  • Christine Maynard
  • Sylvie Sanschagrin
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  • George D W Swerhone
  • James J Dynes
  • Julien Tremblay
  • Charles W Greer
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びまん性大細胞型B細胞リンパ腫におけるベースラインの代謝性総腫瘍負担の自動セグメンテーション：どの方法が最も効果的か？

Automated segmentation of baseline metabolic total tumor burden in diffuse large B-cell lymphoma: which method is most successful ?
  • Sally F Barrington
  • Ben Gjc Zwezerijnen
  • Henrica Cw de Vet
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  • N George Mikhaeel
  • Coreline N Burggraaff
  • Jakoba J Eertink
  • Lucy C Pike
  • Otto S Hoekstra
  • Josee M Zijlstra
  • Ronald Boellaard
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マラリア原虫メロゾイト表面タンパク質1（PmMSP1）の組換えタンパク質。BALB/cモデルでの免疫原性試験と診断ツールとしての利用の可能性

Recombinant proteins of Plasmodium malariae merozoite surface protein 1 (PmMSP1): Testing immunogenicity in the BALB/c model and potential use as diagnostic tool.
  • Yelina B Elizardez
  • Wesley L Fotoran
  • Andrés J Galisteo Junior
  • Izilda Curado
  • Norival Kesper Junior
  • Eliana F Monteiro
  • Irineu Romero Neto
  • Gerhard Wunderlich
  • Karin Kirchgatter
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血小板活性化因子は、リゾホスファチジルコリン誘発性脱髄を、その受容体依存性および非依存性の効果を介して悪化させる

Platelet-Activating Factor Deteriorates Lysophosphatidylcholine-Induced Demyelination Via Its Receptor-Dependent and -Independent Effects.
  • Zhisen Tian
  • Tianci Chu
  • Lisa B E Shields
  • Qingsan Zhu
  • Yi Ping Zhang
  • Maiying Kong
  • Gregory N Barnes
  • Yuanyi Wang
  • Christopher B Shields
  • Jun Cai
  • Mol. Neurobiol..2020 Jul;10.1007/s12035-020-02003-3. doi: 10.1007/s12035-020-02003-3.Epub 2020-07-13.

Euphorbia umbellataのラテックスの濃縮テルペン画分が白血病細胞のアポトーシスを促進することが明らかになった

Enriched terpenes fractions of Euphorbia umbellata latex promote apoptosis in leukemic cells.
  • Luiza Stolz Cruz
  • Carla Cristine Kanunfre
  • Evelyn Assis de Andrade
  • Alexandre Alves de Oliveira
  • Laura Stolz Cruz
  • Mariane de Faria Moss
  • Guilherme Lanzi Sassaki
  • Leociley Rocha Alencar Menezes
  • Mei Wang
  • Ikhlas Ahmad Khan
  • Flávio Luís Beltrame
  • Chem. Biodivers..2020 Jul;doi: 10.1002/cbdv.202000369.Epub 2020-07-09.

ホスホグルコース異性化酵素の強力な阻害剤としての新規N-置換5-リン酸-d-アラビノンアミド誘導体の合成（英文合成、構造活性相関、結晶学的研究

Novel N-substituted 5-phosphate-d-arabinonamide derivatives as strong inhibitors of phosphoglucose isomerases: Synthesis, structure-activity relationship and crystallographic studies.
  • Lama Ahmad
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  • Noureddine Lazar
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  • Inès Li de la Sierra-Gallay
  • Herman van Tilbeurgh
  • Laurent Salmon
  • Bioorg. Chem..2020 Jun;102:104048. S0045-2068(20)31345-6. doi: 10.1016/j.bioorg.2020.104048.Epub 2020-06-29.

血漿中メチルクエン酸と他の疾患バイオマーカーとの相関。プロピオン酸およびメチルマロン酸血症患者のフォローアップにおける影響

Plasma Methylcitric Acid and Its Correlations With Other Disease Biomarkers: The Impact in The Follow Up of Patients With Propionic and Methylmalonic Acidemia.
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  • A Maiorana
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ラミナリン由来グルコグルクロナンの構造解析とその抗肺癌活性のメカニズムの解明

Structural analysis of a glucoglucuronan derived from laminarin and the mechanisms of its anti-lung cancer activity.
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  • Xinyue He
  • Wanli Wu
  • Yizhong Bao
  • Sanying Wang
  • Min Cai
  • Wenjing Zhang
  • Chunyu Wang
  • Fuming Zhang
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  • Genxiang Mao
  • Weihong Zhong
  • Int. J. Biol. Macromol..2020 Jul;163:776-787. S0141-8130(20)33822-8. doi: 10.1016/j.ijbiomac.2020.07.069.Epub 2020-07-10.

メソセリンを標的とした免疫毒素LMB-100および抗PD-1抗体の中皮腫患者およびマウス腫瘍モデルにおける有効性を増強しました

Enhanced efficacy of mesothelin-targeted immunotoxin LMB-100 and anti-PD-1 antibody in patients with mesothelioma and mouse tumor models.
  • Qun Jiang
  • Azam Ghafoor
  • Idrees Mian
  • Daniel Rathkey
  • Anish Thomas
  • Christine Alewine
  • Manjistha Sengupta
  • Mark A Ahlman
  • Jingli Zhang
  • Betsy Morrow
  • Seth M Steinberg
  • Ira Pastan
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  • Sci Transl Med.2020 Jul;12(550). eaaz7252. doi: 10.1126/scitranslmed.aaz7252.

環境関連濃度のジオスミンは、ゼブラフィッシュの発生、酸化ストレス、アポトーシス、内分泌かく乱に影響を与える

Environmentally relevant concentrations of geosmin affect the development, oxidative stress, apoptosis and endocrine disruption of embryo-larval zebrafish.
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  • Jinli Zhang
  • Chengrong Peng
  • Genbao Li
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  • Sci. Total Environ..2020 Sep;735:139373. S0048-9697(20)32890-4. doi: 10.1016/j.scitotenv.2020.139373.Epub 2020-05-13.

重度の熱傷を負って生存している患者の患者特性と手技の回数および滞在期間の関係。米国熱傷協会全国熱傷リポジトリの分析

Relationship Between Patient Characteristics and Number of Procedures as well as Length of Stay for Patients Surviving Severe Burn Injuries: Analysis of the American Burn Association National Burn Repository.
  • Eliza Kruger
  • Stacey Kowal
  • S Pinar Bilir
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  • Kevin Foster
  • J Burn Care Res.2020 Mar;iraa040. doi: 10.1093/jbcr/iraa040.Epub 2020-03-28.

イラン南部ホルムズガン州におけるジヒドロ葉酸還元酵素およびジヒドロプテロン酸合成酵素遺伝子のアミノ酸変異

Amino acid mutation in dihydrofolate reductase and dihydropteroate synthetase genes in Hormozgan Province, southern Iran.
  • Somayeh Maghsoodloorad
  • Nahid Hosseinzadeh
  • Ali Haghighi
  • Rahmat Solgi
  • Mustapha Ahmed Yusuf
  • Gholamreza Hatam
  • J Vector Borne Dis.2019 Apr-Jun;56(2):170-173. JVectorBorneDis_2019_56_2_170_263716. doi: 10.4103/0972-9062.263716.

角膜に対する最適なアプローチとしての直径9mm径DALKの意図的なDALKマンデートからのコンバーテッドマッシュルーム角膜形成術の5年後のアウトカム

5-year Outcomes of Converted Mushroom Keratoplasty from Intended DALK Mandate 9mm Diameter DALK as the Optimal Approach to Keratoconus.
  • James Myerscough
  • Harry Roberts
  • Angeli Christy Yu
  • Mohamed Elkadim
  • Cristina Bovone
  • Massimo Busin
  • Am. J. Ophthalmol..2020 Jul;S0002-9394(20)30360-3. doi: 10.1016/j.ajo.2020.07.009.Epub 2020-07-15.

成長抑制のためのヘッドギアを使用したガミースマイルを伴う骨格性上顎前突の非外科的治療、上顎切歯侵入のためのアンカレッジとしてのミニインプラント、切歯退縮のための前臼歯摘出術

Nonsurgical treatment of skeletal maxillary protrusion with gummy smile using headgear for growth control, mini-implants as anchorage for maxillary incisor intrusion, and premolar extractions for incisor retraction.
  • Armando Yukio Saga
  • Eustáquio Afonso Araújo
  • Oscar Mario Antelo
  • Thiago Martins Meira
  • Orlando Motohiro Tanaka
  • Am J Orthod Dentofacial Orthop.2020 Feb;157(2):245-258. S0889-5406(19)30762-0. doi: 10.1016/j.ajodo.2018.09.021.

ロボット支援腹腔鏡下前立腺摘出術における電気インピーダンス断層撮影による個別化された呼気終末圧のガイド：プロスペクティブ、無作為化比較臨床試験

Individualised positive end-expiratory pressure guided by electrical impedance tomography for robot-assisted laparoscopic radical prostatectomy: a prospective, randomised controlled clinical trial.
  • Felix Girrbach
  • David Petroff
  • Susann Schulz
  • Gunther Hempel
  • Mirko Lange
  • Carolin Klotz
  • Stephanie Scherz
  • Antonio Giannella-Neto
  • Alessandro Beda
  • Alcendino Jardim-Neto
  • Jens-Uwe Stolzenburg
  • Andreas W Reske
  • Hermann Wrigge
  • Philipp Simon
  • Br J Anaesth.2020 Jul;S0007-0912(20)30423-2. doi: 10.1016/j.bja.2020.05.041.Epub 2020-07-11.

オイゲノール、トランス-シンナムアルデヒド、シトロネロール、およびテルピネオールの培養依存性および非依存性の方法で評価されたバイオフィルム制御への効果

The Effects of Eugenol, Trans-Cinnamaldehyde, Citronellol, and Terpineol on Biofilm Control as Assessed by Culture-Dependent and -Independent Methods.
  • Magdalena A Olszewska
  • Astrid Gędas
  • Manuel Simões
  • Molecules.2020 Jun;25(11). E2641. doi: 10.3390/molecules25112641.Epub 2020-06-06.

高性能リチウムイオン電池用負極材料として、N,Sコドープカーボンナノチューブ上に装飾したFeSナノ結晶をその場で合成した

In-situ synthesis of FeS nanocrystals decorated on N, S-codoped carbon nanotubes as anode material for high-performance lithium-ion batteries.
  • Xiaojie Zhang
  • Xiaoyan Gao
  • Junfeng Li
  • Kun Hong
  • Lei Wu
  • Shigang Xu
  • Kailong Zhang
  • Chenzhen Liu
  • Zhonghao Rao
  • J Colloid Interface Sci.2020 Jun;579:699-706. S0021-9797(20)30832-8. doi: 10.1016/j.jcis.2020.06.087.Epub 2020-06-26.

インターロイキン-23は、去勢抵抗性前立腺癌細胞におけるアンドロゲン受容体拮抗薬エンザルタミドとダロルタミドによって誘導される細胞の老化を抑制する

Interleukin-23 Represses the Level of Cell Senescence Induced by the Androgen Receptor Antagonists Enzalutamide and Darolutamide in Castration-Resistant Prostate Cancer Cells.
  • Siddharth Gupta
  • Thanakorn Pungsrinont
  • Ondrej Ženata
  • Laura Neubert
  • Radim Vrzal
  • Aria Baniahmad
  • Horm Cancer.2020 Aug;11(3-4):182-190. 10.1007/s12672-020-00391-5. doi: 10.1007/s12672-020-00391-5.Epub 2020-06-20.

伝導障害、拡張型心筋症、心臓突然死の家族歴を有するc.475G>T, p.E159*ラミネートA/C変異の症例報告

Case reports of a c.475G>T, p.E159* lamin A/C mutation with a family history of conduction disorder, dilated cardiomyopathy and sudden cardiac death.
  • Tetsuro Yokokawa
  • Shohei Ichimura
  • Naoko Hijioka
  • Takashi Kaneshiro
  • Akiomi Yoshihisa
  • Hiroyuki Kunii
  • Kazuhiko Nakazato
  • Takafumi Ishida
  • Osamu Suzuki
  • Seiko Ohno
  • Takeshi Aiba
  • Hiroshi Ohtani
  • Yasuchika Takeishi
  • BMC Cardiovasc Disord.2019 12;19(1):298. 10.1186/s12872-019-01282-6. doi: 10.1186/s12872-019-01282-6.Epub 2019-12-17.

インスリン負荷pH応答性ナノインマイクロ粒子のオールインワンマイクロ流体アセンブリの経口インスリン送達のための

All-in-one microfluidic assembly of insulin-loaded pH-responsive nano-in-microparticles for oral insulin delivery.
  • Clarinda Costa
  • Zehua Liu
  • João P Martins
  • Alexandra Correia
  • Patrícia Figueiredo
  • Antti Rahikkala
  • Wei Li
  • Jani Seitsonen
  • Janne Ruokolainen
  • Sami-Pekka Hirvonen
  • Ana Aguiar-Ricardo
  • M Luísa Corvo
  • Hélder A Santos
  • Biomater Sci.2020 Jun;8(12):3270-3277. doi: 10.1039/d0bm00743a.Epub 2020-06-03.

連想遺伝学的解析により、ノルウェー産トウヒのラッカーゼ遺伝子PaLAC5が特異的に制御され、Heterobasidion parviporumの抵抗性と関連していることが明らかになった

Association genetics identifies a specifically regulated Norway spruce laccase gene, PaLAC5, linked to Heterobasidion parviporum resistance.
  • Malin Elfstrand
  • John Baison
  • Karl Lundén
  • Linghua Zhou
  • Ingrid Vos
  • Hernan Dario Capador
  • Matilda Stein Åslund
  • Zhiqiang Chen
  • Rajiv Chaudhary
  • Åke Olson
  • Harry X Wu
  • Bo Karlsson
  • Jan Stenlid
  • María Rosario García-Gil
  • Plant Cell Environ..2020 Jul;43(7):1779-1791. doi: 10.1111/pce.13768.Epub 2020-04-29.

レジリエンス、トラウマ、絶望感：移民の間での精神病理学の発達のための保護因子か、それとも誘発因子か？

Resilience, trauma, and hopelessness: protective or triggering factor for the development of psychopathology among migrants?
  • Eleonora Gambaro
  • Martina Mastrangelo
  • Marco Sarchiapone
  • Debora Marangon
  • Carla Gramaglia
  • Camilla Vecchi
  • Chiara Airoldi
  • Concetta Mirisola
  • Gianfranco Costanzo
  • Silvia Bartollino
  • Francesca Baralla
  • Patrizia Zeppegno
  • BMC Psychiatry.2020 Jul;20(1):358. 10.1186/s12888-020-02729-3. doi: 10.1186/s12888-020-02729-3.Epub 2020-07-08.

複製フォークのリモデリングと再起動におけるRAD51パラログ複合体の逐次的な役割

Sequential role of RAD51 paralog complexes in replication fork remodeling and restart.
  • Matteo Berti
  • Federico Teloni
  • Sofija Mijic
  • Sebastian Ursich
  • Jevgenij Fuchs
  • Maria Dilia Palumbieri
  • Jana Krietsch
  • Jonas A Schmid
  • Edwige B Garcin
  • Stéphanie Gon
  • Mauro Modesti
  • Matthias Altmeyer
  • Massimo Lopes
  • Nat Commun.2020 Jul;11(1):3531. 10.1038/s41467-020-17324-z. doi: 10.1038/s41467-020-17324-z.Epub 2020-07-15.

重症感染症の重症患者における高用量チゲサイクリンの薬物動態

Pharmacokinetics of high-dose tigecycline in critically ill patients with severe infections.
  • Gennaro De Pascale
  • Lucia Lisi
  • Gabriella Maria Pia Ciotti
  • Maria Sole Vallecoccia
  • Salvatore Lucio Cutuli
  • Laura Cascarano
  • Camilla Gelormini
  • Giuseppe Bello
  • Luca Montini
  • Simone Carelli
  • Valentina Di Gravio
  • Mario Tumbarello
  • Maurizio Sanguinetti
  • Pierluigi Navarra
  • Massimo Antonelli
  • Ann Intensive Care.2020 Jul;10(1):94. 10.1186/s13613-020-00715-2. doi: 10.1186/s13613-020-00715-2.Epub 2020-07-13.

再発性再発性多発性硬化症患者の認知および機能障害に対するフマル酸ジメチルの2年間の治療の効果

Effects of 2-year treatment with dimethyl fumarate on cognition and functional impairment in patients with relapsing remitting multiple sclerosis.
  • Maria Pia Amato
  • Benedetta Goretti
  • Vincenzo Brescia Morra
  • Paolo Gallo
  • Mauro Zaffaroni
  • Marco Onofrj
  • Eleonora Cocco
  • Giovanna Borriello
  • Valentina Zipoli
  • Maria Trojano
  • Neurol. Sci..2020 May;10.1007/s10072-020-04320-w. doi: 10.1007/s10072-020-04320-w.Epub 2020-05-01.

癌治療のための薬物送達システムを評価するのに適したin vivoモデルとしてのニワトリ胚絨毛足底膜。A review

Chick embryo chorioallantoic membrane as a suitable in vivo model to evaluate drug delivery systems for cancer treatment: A review.
  • Francesca Damiani Victorelli
  • Valéria Maria de Oliveira Cardoso
  • Natália Noronha Ferreira
  • Giovana Maria Fioramonti Calixto
  • Carla Raquel Fontana
  • Fátima Baltazar
  • Maria Palmira Daflon Gremião
  • Marlus Chorilli
  • Eur J Pharm Biopharm.2020 Aug;153:273-284. S0939-6411(20)30179-X. doi: 10.1016/j.ejpb.2020.06.010.Epub 2020-06-21.

マンバルギン-2はASIC1aとの相互作用により神経膠腫細胞の細胞周期停止とアポトーシスを誘導する

Mambalgin-2 Induces Cell Cycle Arrest and Apoptosis in Glioma Cells via Interaction with ASIC1a.
  • Maxim Bychkov
  • Mikhail Shulepko
  • Dmitry Osmakov
  • Yaroslav Andreev
  • Anastasia Sudarikova
  • Valeria Vasileva
  • Marat S Pavlyukov
  • Yaroslav A Latyshev
  • Alexander A Potapov
  • Mikhail Kirpichnikov
  • Zakhar O Shenkarev
  • Ekaterina Lyukmanova
  • Cancers (Basel).2020 Jul;12(7). E1837. doi: 10.3390/cancers12071837.Epub 2020-07-08.

レビー小体型障害のモデルとしての遺伝性パーキンソン病における心筋MIBGシンチグラフィ

Myocardial MIBG scintigraphy in genetic Parkinson's disease as a model for Lewy body disorders.
  • Iñigo Gabilondo
  • Verónica Llorens
  • Trinidad Rodriguez
  • Manuel Fernández
  • Tomas Pérez Concha
  • Marian Acera
  • Beatriz Tijero
  • Ane Murueta-Goyena
  • Rocío Del Pino
  • Jesús Cortés
  • Juan Carlos Gómez-Esteban
  • Eur. J. Nucl. Med. Mol. Imaging.2019 02;46(2):376-384. 10.1007/s00259-018-4183-0. doi: 10.1007/s00259-018-4183-0.Epub 2018-10-15.

単純なルーチン気管支鏡によるセグメント間平面同定のためのインフレーションを伴う胸腔鏡下セグメンテクトミー：ロベクトミーと比較した短期および中期の転帰

Thoracoscopic segmentectomy with simple routine bronchoscopic inflation for intersegmental plane identification: short and mid-term outcomes compared with lobectomy.
  • Olli Helminen
  • Johanna Valo
  • Heidi Andersen
  • Anna Lautamäki
  • Jari Räsänen
  • Eero Sihvo
  • J Thorac Dis.2020 Jun;12(6):3073-3084. jtd-12-06-3073. doi: 10.21037/jtd-20-656.

ラットモデルにおける臍帯由来間葉系幹細胞と脂肪組織からの勾配細胞外マトリックス足場を用いた腱板腱板腱-骨界面の再生

Regeneration of the Rotator Cuff Tendon-to-Bone Interface using Umbilical Cord-Derived Mesenchymal Stem Cells and Gradient Extracellular Matrix Scaffolds from Adipose Tissue in a Rat Model.
  • Ji-Hye Yea
  • Tae Soo Bae
  • Byoung Jae Kim
  • Yong Woo Cho
  • Chris Hyunchul Jo
  • Acta Biomater.2020 Jul;S1742-7061(20)30406-2. doi: 10.1016/j.actbio.2020.07.020.Epub 2020-07-15.

リポソーマルドキソルビシンのBE試験をサポートするために、安定化凍結ヒト血漿中の遊離、カプセル化、総ドキソルビシンおよびドキソルビシノールを直接定量する

Direct quantitation of free, encapsulated, total doxorubicin and doxorubicinol in stabilized frozen human plasma to support a BE study of liposomal doxorubicin.
  • Yuhuan Ji
  • Xueyuan Zhang
  • Jinzhi Liu
  • Yu Chen
  • Min Meng
  • ChunLei Li
  • Laixin Wang
  • J Pharm Biomed Anal.2020 May;189:113388. S0731-7085(20)31274-7. doi: 10.1016/j.jpba.2020.113388.Epub 2020-05-23.

グリーンランド氷床モデル初期化実験initMIP-Greenlandの設計と結果：ISMIP6の相互比較

Design and results of the ice sheet model initialisation experiments initMIP-Greenland: an ISMIP6 intercomparison.
  • Heiko Goelzer
  • Sophie Nowicki
  • Tamsin Edwards
  • Matthew Beckley
  • Ayako Abe-Ouchi
  • Andy Aschwanden
  • Reinhard Calov
  • Olivier Gagliardini
  • Fabien Gillet-Chaulet
  • Nicholas R Golledge
  • Jonathan Gregory
  • Ralf Greve
  • Angelika Humbert
  • Philippe Huybrechts
  • Joseph H Kennedy
  • Eric Larour
  • William H Lipscomb
  • Sébastien Le Clećh
  • Victoria Lee
  • Mathieu Morlighem
  • Frank Pattyn
  • Antony J Payne
  • Christian Rodehacke
  • Martin Rückamp
  • Fuyuki Saito
  • Nicole Schlegel
  • Helene Seroussi
  • Andrew Shepherd
  • Sainan Sun
  • Roderik van de Wal
  • Florian A Ziemen
  • Cryosphere.2019 Apr;12(4):1433-1460. doi: 10.5194/tc-12-1433-2018.Epub 2019-04-19.

デュアルエンドリードアウト検出器を用いた高解像度小動物PETスキャナのためのGPUアクセラレーションによる完全3次元OSEM画像再構成

A GPU-accelerated fully 3D OSEM image reconstruction for a high-resolution small animal PET scanner using dual-ended readout detectors.
  • Tianyi Zeng
  • Juan Gao
  • Dongfang Gao
  • Zhonghua Kuang
  • Ziru Sang
  • Xiaohui Wang
  • Lingzhi Hu
  • Qun Chen
  • Xu Chu
  • Dong Liang
  • Xin Liu
  • Yongfeng Yang
  • Hairong Zheng
  • Zhanli Hu
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輸血依存性β-タラセミアを有する北インドの青年期および成人患者において、ギルバート症候群（UGT1A1*28/*28）とそれに伴う高ビリルビン血症が高頻度に認められたが、胆石症は認められなかった

A high frequency of Gilbert syndrome (UGT1A1*28/*28) and associated hyperbilirubinemia but not cholelithiasis in adolescent and adult north Indian patients with transfusion-dependent β-thalassemia.
  • Oshan Shrestha
  • Alka Rani Khadwal
  • Manphool Singhal
  • Amita Trehan
  • Deepak Bansal
  • Richa Jain
  • Arnab Pal
  • Jasbir Kaur Hira
  • Sanjeev Chhabra
  • Pankaj Malhotra
  • Reena Das
  • Prashant Sharma
  • Ann. Hematol..2020 Jul;10.1007/s00277-020-04176-2. doi: 10.1007/s00277-020-04176-2.Epub 2020-07-16.

上腕骨近位部骨折の手術管理を受けている患者における合併症の予測における修正虚弱指数と修正Charlson併存率指数の有効性

Efficacy of the modified frailty index and the modified Charlson comorbidity index in predicting complications in patients undergoing operative management of proximal humerus fracture.
  • Brendan C Yi
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  • J Shoulder Elbow Surg.2020 Jul;S1058-2746(20)30531-0. doi: 10.1016/j.jse.2020.06.014.Epub 2020-07-07.

再発・難治性マントル細胞リンパ腫を対象とした3種類の免疫化学療法レジメンとの併用によるテムシロリムスの安全性と有効性、LYSAのT相IB試験の最終結果

Safety and efficacy of temsirolimus in combination with three different immuno-chemotherapy regimens in relapse and refractory mantle cell lymphoma, final results of the T phase IB trial of the LYSA.
  • Benoît Tessoulin
  • Kamal Bouabdallah
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  • Thierry Lamy
  • Remy Gressin
  • Guillaume Cartron
  • Catherine Thieblemont
  • Clémentine Sarkozy
  • Corinne Haioun
  • Olivier Casasnovas
  • Clementine Joubert
  • Emmanuel Gyan
  • Olivier Hermine
  • Steven Le Gouill
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慢性肉芽腫性疾患における造血細胞移植：712人の小児および成人を対象とした研究

Haematopoietic Cell Transplantation in Chronic Granulomatous Disease: a Study on 712 Children and Adults.
  • Robert Chiesa
  • Junfeng Wang
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  • Sheree Hazelaar
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  • Despina Moshous
  • Ansgar S Schulz
  • Manfred Hoenig
  • Fabian Hauck
  • Amal Al Seraihy
  • Jolanta Gozdzik
  • Per T Ljungman
  • Caroline Lindemans
  • Juliana Fernandes
  • Krzysztof Kalwak
  • Brigitte Strahm
  • Urs Schanz
  • Petr Sedlacek
  • Karl-Walter Sykora
  • Serap Aksoylar
  • Franco Locatelli
  • Polina Stepensky
  • Robert F Wynn
  • Su Han Lum
  • Marco Zecca
  • Fulvio Porta
  • Mervi H Taskinen
  • Brenda Es Gibson
  • Susanne Matthes-Martin
  • Musa Karakukcu
  • Mathias M Hauri-Hohl
  • Paul Veys
  • Andrew R Gennery
  • Giovanna Lucchini
  • Matthias Felber
  • Michael H Albert
  • Dmitry Balashov
  • Arjan C Lankester
  • Tayfun Güngör
  • Mary Slatter
  • Blood.2020 Jul;blood.2020005590. doi: 10.1182/blood.2020005590.Epub 2020-07-02.

HOMA-IRと相関する肝トランスクリプトームシグネチャーは、初期のNonalcoholic Fatty Liver Diseaseの病態を説明する

Hepatic transcriptome signature correlated with HOMA-IR explains early Nonalcoholic Fatty Liver Disease pathogenesis.
  • Ankita Chatterjee
  • Analabha Basu
  • Kausik Das
  • Pankaj Singh
  • Dipankar Mondal
  • Biswanath Bhattacharya
  • Shweta Roychoudhury
  • Partha P Majumder
  • Abhijit Chowdhury
  • Priyadarshi Basu
  • Ann Hepatol.2020 Jul;S1665-2681(20)30070-3. doi: 10.1016/j.aohep.2020.06.009.Epub 2020-07-15.

ビタミン B12 欠乏症の焼ける口症候群患者における貧血、ヘマチン欠乏症、高ホモシステイン血症、胃頭頂細胞抗体陽性

Anemia, hematinic deficiencies, hyperhomocysteinemia, and gastric parietal cell antibody positivity in burning mouth syndrome patients with vitamin B12 deficiency.
  • Meng-Ling Chiang
  • Ying-Tai Jin
  • Chun-Pin Chiang
  • Yu-Hsueh Wu
  • Julia Yu-Fong Chang
  • Andy Sun
  • J Dent Sci.2020 Mar;15(1):34-41. S1991-7902(19)30857-8. doi: 10.1016/j.jds.2019.12.002.Epub 2019-12-24.

細胞解析と比較トランスクリプトームにより、フェノールに対する耐性メカニズムが明らかにされた

Cellular Analysis and Comparative Transcriptomics Reveal the Tolerance Mechanisms of Toward Phenol.
  • Hanyu Wang
  • Qian Li
  • Yuanyuan Peng
  • Zhengyue Zhang
  • Xiaolin Kuang
  • Xiangdong Hu
  • Ellen Ayepa
  • Xuebing Han
  • Getachew Tafere Abrha
  • Quanju Xiang
  • Xiumei Yu
  • Ke Zhao
  • Likou Zou
  • Yunfu Gu
  • Xi Li
  • Xiaoying Li
  • Qiang Chen
  • Xiaoping Zhang
  • Beidong Liu
  • Menggen Ma
  • Front Microbiol.2020;11:544. doi: 10.3389/fmicb.2020.00544.Epub 2020-04-15.

著者訂正。アポスタシアゲノムとランの進化

Author Correction: The Apostasia genome and the evolution of orchids.
  • Guo-Qiang Zhang
  • Ke-Wei Liu
  • Zhen Li
  • Rolf Lohaus
  • Yu-Yun Hsiao
  • Shan-Ce Niu
  • Jie-Yu Wang
  • Yao-Cheng Lin
  • Qing Xu
  • Li-Jun Chen
  • Kouki Yoshida
  • Sumire Fujiwara
  • Zhi-Wen Wang
  • Yong-Qiang Zhang
  • Nobutaka Mitsuda
  • Meina Wang
  • Guo-Hui Liu
  • Lorenzo Pecoraro
  • Hui-Xia Huang
  • Xin-Ju Xiao
  • Min Lin
  • Xin-Yi Wu
  • Wan-Lin Wu
  • You-Yi Chen
  • Song-Bin Chang
  • Shingo Sakamoto
  • Masaru Ohme-Takagi
  • Masafumi Yagi
  • Si-Jin Zeng
  • Ching-Yu Shen
  • Chuan-Ming Yeh
  • Yi-Bo Luo
  • Wen-Chieh Tsai
  • Yves Van de Peer
  • Zhong-Jian Liu
  • Nature.2020 Jul;10.1038/s41586-020-2524-1. doi: 10.1038/s41586-020-2524-1.Epub 2020-07-17.

SARS-CoV-2 感染の垂直伝播の可能性．

Probable Vertical Transmission of SARS-CoV-2 Infection.
  • Alicia Demirjian
  • Cheentan Singh
  • Marc Tebruegge
  • Rachel Herbert
  • Nehal Draz
  • Mariyam Mirfenderesky
  • Victoria Jones
  • Peter Hinstridge
  • Ranjika Seneviratne
  • Richard Myers
  • Joanna Ellis
  • Shahjahan Miah
  • Christopher Is Meadows
  • Julia Kenny
  • Alejandra Alonso
  • Jennifer Handforth
  • Shona Perkins
  • Mark Butler
  • Frances Blackburn
  • Sam Douthwaite
  • Deenan Pillay
  • Meera Chand
  • Maria Zambon
  • Pediatr. Infect. Dis. J..2020 Jul;doi: 10.1097/INF.0000000000002821.Epub 2020-07-10.

ヨーロッパにおける自閉症スペクトラム症スクリーニングツールの理論的枠組みの構築

Building a theoretical framework for autism spectrum disorders screening instruments in Europe.
  • María Magán-Maganto
  • Sigrídur Lóa Jónsdóttir
  • Ana B Sánchez-García
  • Patricia García-Primo
  • Annika Hellendoorn
  • Tony Charman
  • Herbert Roeyers
  • Mieke Dereu
  • Irma Moilanen
  • Filippo Muratori
  • Manuel Posada de la Paz
  • Bernadette Rogé
  • Iris J Oosterling
  • Anneli Yliherva
  • Ricardo Canal-Bedia
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デグルデックへの切り替えは，使用される定義や患者の特徴にかかわらず，低血糖の減少と関連している．ReFLeCTプロスペクティブ観察研究の二次解析

Switching to Degludec is Associated with Reduced Hypoglycaemia, Irrespective of Definition Used or Patient Characteristics: Secondary Analysis of the ReFLeCT Prospective, Observational Study.
  • Harold W de Valk
  • Michael Feher
  • Troels Krarup Hansen
  • Johan Jendle
  • Mette Marie Koefoed
  • Ehsan Parvaresh Rizi
  • Esther Zimmermann
  • Gian Paolo Fadini
  • Diabetes Ther.2020 Jul;10.1007/s13300-020-00875-1. doi: 10.1007/s13300-020-00875-1.Epub 2020-07-14.

酵母Bi-Genomicミトコンドリア-Split-GFPを用いた二重局在化タンパク質のミトコンドリア局在化の割り当て

Assigning mitochondrial localization of dual localized proteins using a yeast Bi-Genomic Mitochondrial-Split-GFP.
  • Gaétan Bader
  • Ludovic Enkler
  • Yuhei Araiso
  • Marine Hemmerle
  • Krystyna Binko
  • Emilia Baranowska
  • Johan-Owen De Craene
  • Julie Ruer-Laventie
  • Jean Pieters
  • Déborah Tribouillard-Tanvier
  • Bruno Senger
  • Jean-Paul di Rago
  • Sylvie Friant
  • Roza Kucharczyk
  • Hubert Dominique Becker
  • Elife.2020 Jul;9. e56649. doi: 10.7554/eLife.56649.Epub 2020-07-13.

重度の親密なパートナーからの暴力は、HIVとともに生きる女性の全死因死亡率と関連していた

Severe intimate partner violence is associated with all-cause mortality among women living with HIV.
  • Kalysha Closson
  • Taylor McLinden
  • Rebeccah Parry
  • Melanie Lee
  • Andrew Gibbs
  • Mia Kibel
  • Lu Wang
  • Jason Trigg
  • Paula Braitstein
  • Neora Pick
  • Surita Parashar
  • Julio S G Montaner
  • Angela Kaida
  • Robert S Hogg
  • AIDS.2020 Aug;34(10):1549-1558. 00002030-202008010-00013. doi: 10.1097/QAD.0000000000002581.

多環芳香族炭化水素の皮膚への吸収による皮膚炎症の誘発。構造-透過性とin silico-in vitro-in vivoの関係を確立する

The absorption of polycyclic aromatic hydrocarbons into the skin to elicit cutaneous inflammation: The establishment of structure-permeation and in silico-in vitro-in vivo relationships.
  • Ahmed Alalaiwe
  • Yin-Ku Lin
  • Chih-Hung Lin
  • Pei-Wen Wang
  • Jie-Yu Lin
  • Jia-You Fang
  • Chemosphere.2020 Sep;255:126955. S0045-6535(20)31148-6. doi: 10.1016/j.chemosphere.2020.126955.Epub 2020-05-07.

ZFYVE26遺伝子に新規ホモ接合変異を有する患者におけるI-ioflupane SPECT蓄積量とI-MIBG心筋シンチグラフィの取り込み量の減少

Decreasing I-ioflupane SPECT accumulation and I-MIBG myocardial scintigraphy uptake in a patient with a novel homozygous mutation in the ZFYVE26 gene.
  • Kishin Koh
  • Mai Tsuchiya
  • Takamura Nagasaka
  • Kazumasa Shindo
  • Yoshihisa Takiyama
  • Neurol. Sci..2019 Feb;40(2):429-431. 10.1007/s10072-018-3603-z. doi: 10.1007/s10072-018-3603-z.Epub 2018-10-16.

新型の業務関連呼吸器疾患を持つ製造施設における環境-ヒト微生物群移行の証拠

Evidence for Environmental-human Microbiota Transfer at a Manufacturing Facility with Novel Work-related Respiratory Disease.
  • Benjamin G Wu
  • Bianca Kapoor
  • Kristin J Cummings
  • Marcia L Stanton
  • Randall J Nett
  • Kathleen Kreiss
  • Jerrold L Abraham
  • Thomas V Colby
  • Angela D Franko
  • Francis H Y Green
  • Soma Sanyal
  • Jose C Clemente
  • Zhan Gao
  • Maryaline Coffre
  • Peter Meyn
  • Adriana Heguy
  • Yonghua Li
  • Imran Sulaiman
  • Timothy C Borbet
  • Sergei B Koralov
  • Robert J Tallaksen
  • Douglas Wendland
  • Vance D Bachelder
  • Randy J Boylstein
  • Ju-Hyeong Park
  • Jean M Cox-Ganser
  • M Abbas Virji
  • Judith A Crawford
  • Nicole T Edwards
  • Marc Veillette
  • Caroline Duchaine
  • Krista Warren
  • Sarah Lundeen
  • Martin J Blaser
  • Leopoldo N Segal
  • Am. J. Respir. Crit. Care Med..2020 Jul;doi: 10.1164/rccm.202001-0197OC.Epub 2020-07-16.

ラットモデルにおけるジヒドロカプサイシン誘導血管新生と脳虚血・再灌流後の機能回復改善効果

Dihydrocapsaicin-induced angiogenesis and improved functional recovery after cerebral ischemia and reperfusion in a rat model.
  • Adchara Janyou
  • Piyawadee Wicha
  • Vatcharee Seechamnanturakit
  • Kanokkan Bumroongkit
  • Chainarong Tocharus
  • Apichart Suksamrarn
  • Jiraporn Tocharus
  • J. Pharmacol. Sci..2020 May;143(1):9-16. S1347-8613(20)30013-X. doi: 10.1016/j.jphs.2020.02.001.Epub 2020-02-14.

5-HT/5-HT受容体アンタゴニストおよびホスホジエステラーゼ4/7阻害剤としてのアリールピペラジニルアルカン酸の新規アニリドおよびベンジルアミド誘導体の認知活性および抗うつ活性

Novel anilide and benzylamide derivatives of arylpiperazinylalkanoic acids as 5-HT/5-HT receptor antagonists and phosphodiesterase 4/7 inhibitors with procognitive and antidepressant activity.
  • Agnieszka Jankowska
  • Grzegorz Satała
  • Marcin Kołaczkowski
  • Adam Bucki
  • Monika Głuch-Lutwin
  • Artur Świerczek
  • Krzysztof Pociecha
  • Anna Partyka
  • Magdalena Jastrzębska-Więsek
  • Annamaria Lubelska
  • Gniewomir Latacz
  • Alicja Gawalska
  • Andrzej J Bojarski
  • Elżbieta Wyska
  • Grażyna Chłoń-Rzepa
  • Eur J Med Chem.2020 Jun;201:112437. S0223-5234(20)30408-6. doi: 10.1016/j.ejmech.2020.112437.Epub 2020-06-17.

骨髄異形成症候群および関連新生物患者における低メチル化療法の臨床効果予測におけるTP53変異の役割：システマティックレビューおよびメタアナリシス

Role Of TP53 mutations in predicting the clinical efficacy of hypomethylating therapy in patients with myelodysplastic syndrome and related neoplasms: a systematic review and meta-analysis.
  • Li Cai
  • Xiaoyan Zhao
  • Lisha Ai
  • Huafang Wang
  • Clin. Exp. Med..2020 Aug;20(3):361-371. 10.1007/s10238-020-00641-4. doi: 10.1007/s10238-020-00641-4.Epub 2020-07-01.

ボスニア・ヘルツェゴビナおよびセルビアのウルトラマフィクスから採取したNoccaea kovatsiiの微量元素蓄積能の評価（英文

Assessment of trace element accumulation potential of Noccaea kovatsii from ultramafics of Bosnia and Herzegovina and Serbia.
  • Jasmina Šinzar-Sekulić
  • Una Matko Stamenković
  • Gordana Tomović
  • Ahmed F Tumi
  • Gordana Andrejić
  • Nevena Mihailović
  • Maja R Lazarević
  • Environ Monit Assess.2019 Aug;191(9):540. 10.1007/s10661-019-7711-x. doi: 10.1007/s10661-019-7711-x.Epub 2019-08-05.

IL-1βを共培養した馬の軟骨および滑膜由来の炎症性および異化性遺伝子発現に対する自己調節血清、自己蛋白質溶液、およびトリアムシノロンの効果

Effects of Autologous Conditioned Serum, Autologous Protein Solution, and Triamcinolone on Inflammatory and Catabolic Gene Expression in Equine Cartilage and Synovial Explants Treated With IL-1β in Co-culture.
  • Ana Velloso Alvarez
  • Lindsey H Boone
  • Satyanarayana R Pondugula
  • Fred Caldwell
  • Anne A Wooldridge
  • Front Vet Sci.2020;7:323. doi: 10.3389/fvets.2020.00323.Epub 2020-06-26.

膜貫通型TNFは、ヒトの脊椎関節炎を思わせる骨増殖性関節炎症を促進する

Transmembrane TNF drives osteoproliferative joint inflammation reminiscent of human spondyloarthritis.
  • Merlijn H Kaaij
  • Melissa N van Tok
  • Iris C Blijdorp
  • Carmen A Ambarus
  • Michael Stock
  • Désiree Pots
  • Véronique L Knaup
  • Marietta Armaka
  • Eleni Christodoulou-Vafeiadou
  • Tessa K van Melsen
  • Huriatul Masdar
  • Harry J P P Eskes
  • Nataliya G Yeremenko
  • George Kollias
  • Georg Schett
  • Sander W Tas
  • Leonie M van Duivenvoorde
  • Dominique L P Baeten
  • J. Exp. Med..2020 Oct;217(10). e20200288. doi: 10.1084/jem.20200288.

アストラガロシドは、アセチルコリンを回復させ、脳波を正常化することで、マイクロ波による機能障害からラットの脳を保護します

Astragaloside protects rat brain from microwave-induced functional injuries via restoring acetylcholine and normalizing electroencephalogram.
  • Li Zhao
  • Yunbo Sun
  • Chao Yu
  • Junjun Chen
  • Xinping Xu
  • Xueyan Zhang
  • Hui Wang
  • Jing Zhang
  • Haoyu Wang
  • Ji Dong
  • Binwei Yao
  • Hongmei Zhou
  • Shuchen Liu
  • Ruiyun Peng
  • Environ Sci Pollut Res Int.2020 Jul;10.1007/s11356-020-07915-0. doi: 10.1007/s11356-020-07915-0.Epub 2020-07-16.

資源が限られた環境でのヒト免疫不全ウイルス感染喫煙者への新しい行動的禁煙介入の実施の可能性。単群パイロット試験

Feasibility of implementing a novel behavioural smoking cessation intervention amongst human immunodeficiency virus-infected smokers in a resource-limited setting: A single-arm pilot trial.
  • Billy M Tsima
  • Precious Moedi
  • Joyce Maunge
  • Kitso Machangane
  • Martha Kgogwane
  • Tebogo Mudojwa
  • Joseph Bastian
  • Warren Bilker
  • Rebecca Ashare
  • Robert Schnoll
  • Robert Gross
  • South Afr J HIV Med.2020;21(1):1075. HIVMED-21-1075. doi: 10.4102/sajhivmed.v21i1.1075.Epub 2020-06-24.

ケーブル産業のためのコーティング材料としての緑の高度に粘土充填ポリエチレン複合材料-高分子材料における非有機フィル化天然モンモリロナイトの新しい応用ルート

Green Highly Clay-Filled Polyethylene Composites as Coating Materials for Cable Industry-A New Application Route of Non-Organophilised Natural Montmorillonites in Polymeric Materials.
  • Stanisław Wysocki
  • Krzysztof Kowalczyk
  • Sandra Paszkiewicz
  • Paweł Figiel
  • Elżbieta Piesowicz
  • Polymers (Basel).2020 Jun;12(6). E1399. doi: 10.3390/polym12061399.Epub 2020-06-22.

治療用PSD-95阻害剤と細胞貫通ペプチドTatとの共役は、血液脳関門への付着、取り込み、浸透に影響を与える

Conjugation of Therapeutic PSD-95 Inhibitors to the Cell-Penetrating Peptide Tat Affects Blood-Brain Barrier Adherence, Uptake, and Permeation.
  • Mie Kristensen
  • Krzysztof Kucharz
  • Eduardo Felipe Alves Fernandes
  • Kristian Strømgaard
  • Morten Schallburg Nielsen
  • Hans Christian Cederberg Helms
  • Anders Bach
  • Malte Ulrikkaholm Tofte-Hansen
  • Blanca Irene Aldana Garcia
  • Martin Lauritzen
  • Birger Brodin
  • Pharmaceutics.2020 Jul;12(7). E661. doi: 10.3390/pharmaceutics12070661.Epub 2020-07-14.

慢性頭痛を持つ青年とその保護者を対象とした1日グループ介入「偏頭痛キャンプ」での患者体験の改善

Improving the Patient Experience With Migraine Camp, a One-Day Group Intervention for Adolescents With Chronic Headache and Their Parents.
  • Amanda L Hall
  • Dina Karvounides
  • Amy A Gelfand
  • Haley Mankin
  • Shirley Kessel
  • Janet Corroo
  • Carrie P Malavolta
  • Tara Pezzuto
  • Madeline Chadehumbe
  • Christina L Szperka
  • Headache.2019 09;59(8):1392-1400. doi: 10.1111/head.13570.Epub 2019-06-05.

遺伝的機能障害の根底にある広範な大動脈・頸動脈・腹部解剖を有する患者における欠失の分子的影響の検討

Examination of Molecular Effects of Deletion in a Patient with Extensive Aortic, Carotid, and Abdominal Dissections That Underlie the Genetic Dysfunction.
  • Sarah K Macklin
  • Katelyn A Bruno
  • Charitha Vadlamudi
  • Haytham Helmi
  • Ayesha Samreen
  • Ahmed N Mohammad
  • Stepahnie Hines
  • Paldeep S Atwal
  • Thomas R Caulfield
  • Case Rep Med.2020;2020:5108052. doi: 10.1155/2020/5108052.Epub 2020-06-19.

TLR3および7/8アゴニストベースのDC成熟化カクテルにおけるプロスタグランジンEは、成熟したサイトカイン産生性の遊走性DCを産生するが、CD8 T細胞への抗原クロスプレゼンテーションを損なう

Prostaglandin E in a TLR3- and 7/8-agonist-based DC maturation cocktail generates mature, cytokine-producing, migratory DCs but impairs antigen cross-presentation to CD8 T cells.
  • Philipp Gierlich
  • Veronika Lex
  • Antje Technau
  • Anne Keupp
  • Lorenz Morper
  • Amelie Glunz
  • Hanno Sennholz
  • Johannes Rachor
  • Sascha Sauer
  • Ana Marcu
  • Götz Ulrich Grigoleit
  • Matthias Wölfl
  • Paul G Schlegel
  • Matthias Eyrich
  • Cancer Immunol. Immunother..2020 Jun;69(6):1029-1042. 10.1007/s00262-019-02470-1. doi: 10.1007/s00262-019-02470-1.Epub 2020-02-25.

ドコサヘキサエン酸は、肺動脈平滑筋細胞のmicroRNA-16をアップレギュレートすることでCa流入を抑制し、CaSRをダウンレギュレートする

Docosahexaenoic acid inhibits Ca influx and downregulates CaSR by upregulating microRNA-16 in pulmonary artery smooth muscle cells.
  • Jin-Jun Liu
  • Ming-Ming Tang
  • Ming-Li Zhu
  • Cai-Xia Xie
  • Pin-Fang Kang
  • Xuan Ling
  • Heng Zhang
  • Xiao-Jing Wang
  • Bi Tang
  • J. Biochem. Mol. Toxicol..2020 Jul;:e22573. doi: 10.1002/jbt.22573.Epub 2020-07-13.

スフィンゴシンキナーゼ1/スフィンゴシン1-リン酸塩/スフィンゴシン1-リン酸塩受容体1経路。ゲニポシドによる血管新生抑制の新規ターゲット

Sphingosine kinase 1/sphingosine 1-phosphate/sphingosine 1-phosphate receptor 1 pathway: A novel target of geniposide to inhibit angiogenesis.
  • Minghui Sun
  • Ran Deng
  • Yan Wang
  • Hong Wu
  • Zhengrong Zhang
  • Yanhong Bu
  • Heng Zhang
  • Life Sci..2020 Jun;256:117988. S0024-3205(20)30738-4. doi: 10.1016/j.lfs.2020.117988.Epub 2020-06-20.

全身性疾患の歯周病症状と発生・後天性疾患。2017年歯周病およびインプラント周囲疾患・状態の分類に関する世界ワークショップのワークグループ3のコンセンサス報告書

Periodontal manifestations of systemic diseases and developmental and acquired conditions: Consensus report of workgroup 3 of the 2017 World Workshop on the Classification of Periodontal and Peri-Implant Diseases and Conditions.
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  • Jack G Caton
  • Jasim M Albandar
  • Nabil F Bissada
  • Philippe Bouchard
  • Pierpaolo Cortellini
  • Korkud Demirel
  • Massimo de Sanctis
  • Carlo Ercoli
  • Jingyuan Fan
  • Nicolaas C Geurs
  • Francis J Hughes
  • Lijian Jin
  • Alpdogan Kantarci
  • Evanthia Lalla
  • Phoebus N Madianos
  • Debora Matthews
  • Michael K McGuire
  • Michael P Mills
  • Philip M Preshaw
  • Mark A Reynolds
  • Anton Sculean
  • Cristiano Susin
  • Nicola X West
  • Kazuhisa Yamazaki
  • J. Periodontol..2018 06;89 Suppl 1:S237-S248. doi: 10.1002/JPER.17-0733.

プロトポルフィリンIX上で図示された、非指数的遅延蛍光および燐光減衰分析のための一般的なフレームワーク

A general framework for non-exponential delayed fluorescence and phosphorescence decay analysis, illustrated on Protoporphyrin IX.
  • Gauthier Croizat
  • Aurélien Gregor
  • Emmanuel Gerelli
  • Jaroslava Joniova
  • Marek Scholz
  • Georges Wagnières
  • J. Photochem. Photobiol. B, Biol..2020 Apr;209:111887. S1011-1344(20)30336-5. doi: 10.1016/j.jphotobiol.2020.111887.Epub 2020-04-30.

マルチエコーを用いた拡散強調MRIにおける感度と信号対雑音比の向上

Increased Sensitivity and Signal-to-Noise Ratio in Diffusion-Weighted MRI using Multi-Echo Acquisitions.
  • Cornelius Eichner
  • Michael Paquette
  • Toralf Mildner
  • Torsten Schlumm
  • Kamilla Pleh
  • Liran Samuni
  • Catherine Crockford
  • Roman M Wittig
  • Carsten Jäger
  • Harald E Möller
  • Angela D Friederici
  • Alfred Anwander
  • Neuroimage.2020 Jul;:117172. S1053-8119(20)30658-3. doi: 10.1016/j.neuroimage.2020.117172.Epub 2020-07-15.

溶解性と腸管透過性を改善するためのマイクロエマルジョン中の未熟オリーブ（L. ）からのフェノールリッチ抽出物の製剤化

Formulation of a Phenol-Rich Extract from Unripe Olives ( L.) in Microemulsion to Improve Its Solubility and Intestinal Permeability.
  • Lorenzo Cecchi
  • Vieri Piazzini
  • Mario D'Ambrosio
  • Cristina Luceri
  • Federica Rocco
  • Marzia Innocenti
  • Giulia Vanti
  • Nadia Mulinacci
  • Maria Camilla Bergonzi
  • Molecules.2020 Jul;25(14). E3198. doi: 10.3390/molecules25143198.Epub 2020-07-13.

半閉鎖された亜熱帯の湾内で、環境DNA検出の追跡により、ブラックチップ・シャーク（Carcharhinus limbatus）の季節的な発生が確認された

Environmental DNA detection tracks established seasonal occurrence of blacktip sharks (Carcharhinus limbatus) in a semi-enclosed subtropical bay.
  • Bautisse D Postaire
  • Judith Bakker
  • Jayne Gardiner
  • Tonya R Wiley
  • Demian D Chapman
  • Sci Rep.2020 Jul;10(1):11847. 10.1038/s41598-020-68843-0. doi: 10.1038/s41598-020-68843-0.Epub 2020-07-16.

Nulliparous 思春期の青年および若い女性におけるレボノルゲストレル放出型子宮内装置挿入の12時間前の膣ディノプロストンの自己投与の利点。無作為化対照試験

Benefits of Self-administered Vaginal Dinoprostone 12 Hours before Levonorgestrel-releasing Intrauterine Device Insertion in Nulliparous Adolescents and Young Women: A Randomized Controlled Trial.
  • Ahmed Samy
  • Ahmed Said Ali
  • Dina Latif
  • Fatma Faisal Darweesh
  • Nevein Kamal Ghamry
  • Ahmed A Metwally
  • J Pediatr Adolesc Gynecol.2020 Feb;S1083-3188(20)30163-7. doi: 10.1016/j.jpag.2020.02.010.Epub 2020-02-28.

退役軍人健康管理局（Veterans Health Administration）で前立腺がんと診断された患者の平均余命推定値

Life expectancy estimates for patients diagnosed with prostate cancer in the Veterans Health Administration.
  • Ericka M Sohlberg
  • I-Chun Thomas
  • Jaden Yang
  • Kristopher Kapphahn
  • Timothy J Daskivich
  • Ted A Skolarus
  • Jeremy B Shelton
  • Danil V Makarov
  • Jonathan Bergman
  • Christine Ko Bang
  • Mary K Goldstein
  • Todd H Wagner
  • James D Brooks
  • Manisha Desai
  • John T Leppert
  • Urol. Oncol..2020 Jul;S1078-1439(20)30219-2. doi: 10.1016/j.urolonc.2020.05.015.Epub 2020-07-13.

慢性疾患における注射剤治療の提供と管理における促進要因と障壁に関する統合的レビュー。ACNAPプロジェクト「心血管疾患患者における注射薬」の一部

An integrative review on facilitators and barriers in delivering and managing injectable therapies in chronic conditions: A part of the ACNAP project 'injectable medicines among patients with cardiovascular conditions'.
  • Ekaterini Lambrinou
  • Martha Kyriakou
  • Ioanna Lakatamitou
  • Neil Angus
  • Rani Khatib
  • Ercole Vellone
  • Abigail Barrowcliff
  • Tina Birgitte Hansen
  • Geraldine A Lee
  • Eur J Cardiovasc Nurs.2020 Jul;:1474515120939007. doi: 10.1177/1474515120939007.Epub 2020-07-16.

ヒトの新生児のエタノール臭に対する呼吸と感情の反応性は、妊娠中の母親の飲酒パターンに依存している

Respiratory and emotional reactivity to ethanol odor in human neonates is dependent upon maternal drinking patterns during pregnancy.
  • Florencia Anunziata
  • Ana Fabiola Macchione
  • Adriana Sofía Mitrano
  • Génesis D'aloisio
  • Mirta Elena Ferreyra
  • Ricardo David Pontoriero
  • Luis Alberto Ahumada
  • Juan Carlos Molina
  • Drug Alcohol Depend.2020 Jun;213:108100. S0376-8716(20)30265-9. doi: 10.1016/j.drugalcdep.2020.108100.Epub 2020-06-11.

Bowman-Birk阻害剤とその由来ペプチドの血圧低下効果

Blood pressure-lowering effects of a Bowman-Birk inhibitor and its derived peptides in normotensive and hypertensive rats.
  • Maria Alzira Garcia de Freitas
  • Nathalia Oda Amaral
  • Alice da Cunha Morales Álvares
  • Sandriele Aires de Oliveira
  • Azadeh Mehdad
  • Diego Elias Honda
  • Amanda Sá Martins Bessa
  • Marcelo Henrique Soller Ramada
  • Lara Marques Naves
  • Carolina Nobre Ribeiro Pontes
  • Carlos Henrique Castro
  • Gustavo Rodrigues Pedrino
  • Sonia Maria de Freitas
  • Sci Rep.2020 Jul;10(1):11680. 10.1038/s41598-020-66624-3. doi: 10.1038/s41598-020-66624-3.Epub 2020-07-15.

早期生活環境曝露と小児肥満。エクスポゾンワイドアプローチ

Early-Life Environmental Exposures and Childhood Obesity: An Exposome-Wide Approach.
  • Martine Vrijheid
  • Serena Fossati
  • Léa Maitre
  • Sandra Márquez
  • Theano Roumeliotaki
  • Lydiane Agier
  • Sandra Andrusaityte
  • Solène Cadiou
  • Maribel Casas
  • Montserrat de Castro
  • Audrius Dedele
  • David Donaire-Gonzalez
  • Regina Grazuleviciene
  • Line S Haug
  • Rosemary McEachan
  • Helle Margrete Meltzer
  • Eleni Papadopouplou
  • Oliver Robinson
  • Amrit K Sakhi
  • Valerie Siroux
  • Jordi Sunyer
  • Per E Schwarze
  • Ibon Tamayo-Uria
  • Jose Urquiza
  • Marina Vafeiadi
  • Antonia Valentin
  • Charline Warembourg
  • John Wright
  • Mark J Nieuwenhuijsen
  • Cathrine Thomsen
  • Xavier Basagaña
  • Rémy Slama
  • Leda Chatzi
  • Environ. Health Perspect..2020 Jun;128(6):67009. doi: 10.1289/EHP5975.Epub 2020-06-24.

色素上皮由来の新規ナチュラルキラー細胞由来因子である色素上皮由来因子は、妊娠初期に抗炎症と抗アポトーシスを介して間質細胞を保護する

Pigment epithelium-derived factor, a novel decidual natural killer cells-derived factor, protects decidual stromal cells via anti-inflammation and anti-apoptosis in early pregnancy.
  • Ji Zheng
  • Yanhong Li
  • Yifei Sang
  • Ling Xu
  • Xueling Jin
  • Yu Tao
  • Dajin Li
  • Meirong Du
  • Hum. Reprod..2020 Jul;35(7):1537-1552. 5858162. doi: 10.1093/humrep/deaa118.

EPSTI1の上昇は、原発性シェーグレン症候群患者においてNF-κBシグナルを介してB細胞の過剰活性化を促進する

Elevated EPSTI1 promote B cell hyperactivation through NF-κB signalling in patients with primary Sjögren's syndrome.
  • Jin-Lei Sun
  • Hao-Ze Zhang
  • Su-Ying Liu
  • Chao-Feng Lian
  • Zhi-Lei Chen
  • Ti-Hong Shao
  • Shuo Zhang
  • Li-Ling Zhao
  • Cheng-Mei He
  • Mu Wang
  • Wen Zhang
  • Hua Chen
  • Feng-Chun Zhang
  • Ann. Rheum. Dis..2020 04;79(4):518-524. annrheumdis-2019-216428. doi: 10.1136/annrheumdis-2019-216428.Epub 2020-02-29.

甲状腺ホルモン受容体によるtRNAメチルトランスフェラーゼ様1(Mettl1)遺伝子の直接的な活性化は、成体の腸管幹細胞の発生と変態期の増殖に関与していることを示唆している

Direct activation of tRNA methyltransferase-like 1 (Mettl1) gene by thyroid hormone receptor implicates a role in adult intestinal stem cell development and proliferation during metamorphosis.
  • Wonho Na
  • Liezhen Fu
  • Nga Luu
  • Yun-Bo Shi
  • Cell Biosci.2020;10:60. 423. doi: 10.1186/s13578-020-00423-1.Epub 2020-05-04.

カスパーゼ11はアレルギー性気道炎症を促進する

Caspase-11 promotes allergic airway inflammation.
  • Zbigniew Zasłona
  • Ewelina Flis
  • Mieszko M Wilk
  • Richard G Carroll
  • Eva M Palsson-McDermott
  • Mark M Hughes
  • Ciana Diskin
  • Kathy Banahan
  • Dylan G Ryan
  • Alexander Hooftman
  • Alicja Misiak
  • Jay Kearney
  • Gunter Lochnit
  • Wilhelm Bertrams
  • Timm Greulich
  • Bernd Schmeck
  • Oliver J McElvaney
  • Kingston H G Mills
  • Ed C Lavelle
  • Małgorzata Wygrecka
  • Emma M Creagh
  • Luke A J O'Neill
  • Nat Commun.2020 02;11(1):1055. 10.1038/s41467-020-14945-2. doi: 10.1038/s41467-020-14945-2.Epub 2020-02-26.

外傷を受けた上顎中切歯の治療と審美的管理に歯内療法とインサイド/アウトサイドブリーチング法を用いた．臨床報告

Treatment and esthetic management of traumatized maxillary central incisors with endodontic therapy and the inside/outside bleaching technique: A clinical report.
  • Michael L Myers
  • Mario F Romero
  • Lisiane F Susin
  • Courtney S Babb
  • J Prosthet Dent.2019 Oct;122(4):343-347. S0022-3913(18)31019-9. doi: 10.1016/j.prosdent.2018.10.020.Epub 2019-04-23.

心血管リスク因子は脳卒中重症度と先行認知機能障害を介して脳卒中後の急性認知に間接的に影響を与える：モデレートされた媒介分析

Cardiovascular risk factors indirectly affect acute post-stroke cognition through stroke severity and prior cognitive impairment: a moderated mediation analysis.
  • Bogna A Drozdowska
  • Emma Elliott
  • Martin Taylor-Rowan
  • Robert C Shaw
  • Gillian Cuthbertson
  • Peter Langhorne
  • Terence J Quinn
  • Alzheimers Res Ther.2020 Jul;12(1):85. 10.1186/s13195-020-00653-y. doi: 10.1186/s13195-020-00653-y.Epub 2020-07-16.

式：text参照、黒人参由来の希少なプロトパナキサトリオール型ジンセノサイド画分、Suppresses Inflammatory Gene iNOS via the Iinhibition of p-STAT-1 and NF-Formula：textB

[Formula: see text], a Rare Protopanaxatriol-Type Ginsenoside Fraction from Black Ginseng, Suppresses Inflammatory Gene iNOS via the Iinhibition of p-STAT-1 and NF-[Formula: see text]B.
  • So Yeon Jeong
  • Ji-Eun Kim
  • Gyu-Yong Song
  • Jong-Sup Bae
  • Am. J. Chin. Med..2020;48(5):1091-1102. doi: 10.1142/S0192415X20500536.

肝臓科プロバイダーのトレーニングは、アルコール使用障害のスクリーニングとその結果としての介入を改善する

Training of hepatology providers improves the screening and resultant interventions for alcohol use disorder.
  • Hamzeh Saraireh
  • Joseph Redman
  • Thaer Abdelfattah
  • Sasha Mangray
  • James B Wade
  • HoChong S Gilles
  • Michael Fuchs
  • April Morris
  • Zenaida Malpaya
  • Puneet Puri
  • Brian C Davis
  • Samarth S Patel
  • Jasmohan S Bajaj
  • Liver Int..2020 Jul;doi: 10.1111/liv.14589.Epub 2020-07-07.

PD-L1発現率≧50％のNSCLC患者の大規模実世界コホートにおけるペムブロリズマブの免疫関連有害事象と臨床成績との関係

Immune-related Adverse Events of Pembrolizumab in a Large Real-world Cohort of Patients With NSCLC With a PD-L1 Expression ≥ 50% and Their Relationship With Clinical Outcomes.
  • Alessio Cortellini
  • Alex Friedlaender
  • Giuseppe L Banna
  • Giampiero Porzio
  • Melissa Bersanelli
  • Federico Cappuzzo
  • Joachim G J V Aerts
  • Raffaele Giusti
  • Emilio Bria
  • Diego Cortinovis
  • Francesco Grossi
  • Maria R Migliorino
  • Domenico Galetta
  • Francesco Passiglia
  • Rossana Berardi
  • Francesca Mazzoni
  • Vincenzo Di Noia
  • Diego Signorelli
  • Alessandro Tuzi
  • Alain Gelibter
  • Paolo Marchetti
  • Marianna Macerelli
  • Francesca Rastelli
  • Rita Chiari
  • Danilo Rocco
  • Alessandro Inno
  • Pietro Di Marino
  • Giovanni Mansueto
  • Federica Zoratto
  • Matteo Santoni
  • Marianna Tudini
  • Michele Ghidini
  • Marco Filetti
  • Annamaria Catino
  • Pamela Pizzutilo
  • Luca Sala
  • Mario Alberto Occhipinti
  • Fabrizio Citarella
  • Russano Marco
  • Mariangela Torniai
  • Luca Cantini
  • Alessandro Follador
  • Vincenzo Sforza
  • Olga Nigro
  • Miriam G Ferrara
  • Ettore D'Argento
  • Alessandro Leonetti
  • Linda Pettoruti
  • Lorenzo Antonuzzo
  • Simona Scodes
  • Lorenza Landi
  • Giorgia Guaitoli
  • Cinzia Baldessari
  • Federica Bertolini
  • Luigi Della Gravara
  • Maria Giovanna Dal Bello
  • Robert A Belderbos
  • Marco De Filippis
  • Cristina Cecchi
  • Serena Ricciardi
  • Clelia Donisi
  • Alessandro De Toma
  • Claudia Proto
  • Alfredo Addeo
  • Ornella Cantale
  • Biagio Ricciuti
  • Carlo Genova
  • Alessandro Morabito
  • Daniele Santini
  • Corrado Ficorella
  • Katia Cannita
  • Clin Lung Cancer.2020 Jun;S1525-7304(20)30204-7. doi: 10.1016/j.cllc.2020.06.010.Epub 2020-06-21.

フラクトース含有糖類の主要な食品供給源と罹患メタボリックシンドロームとの関連。システマティックレビューとメタアナリシス

Association of Major Food Sources of Fructose-Containing Sugars With Incident Metabolic Syndrome: A Systematic Review and Meta-analysis.
  • Zhila Semnani-Azad
  • Tauseef A Khan
  • Sonia Blanco Mejia
  • Russell J de Souza
  • Lawrence A Leiter
  • Cyril W C Kendall
  • Anthony J Hanley
  • John L Sievenpiper
  • JAMA Netw Open.2020 Jul;3(7):e209993. 2768092. doi: 10.1001/jamanetworkopen.2020.9993.Epub 2020-07-01.

一酸化窒素/cGMPシグナル伝達経路とカリウムチャネルがノトファギンの血圧降下作用に寄与していることを明らかにした

Nitric oxide/cGMP signaling pathway and potassium channels contribute to hypotensive effects of nothofagin.
  • Claudio H da Silva
  • Rhanany A Palozi
  • Priscila de Souza
  • Camila L de Almeida
  • Valdir Cechinel-Filho
  • Emerson L Lourenço
  • Arquimedes Gasparotto Junior
  • Minerva Cardioangiol.2020 Jul;S0026-4725.20.05243-3. doi: 10.23736/S0026-4725.20.05243-3.Epub 2020-07-10.

高リスク神経芽腫I-mIBG治療症例におけるより個別化医療のためのバイオドシメトリーツールとしての二心染色体アッセイの評価

Assessment of the dicentric chromosome assay as a biodosimetry tool for more personalized medicine in a case of a high risk neuroblastoma I-mIBG treatment.
  • Jose Maria Chimeno
  • Natividad Sebastià
  • Irene Torres-Espallardo
  • Julia Balaguer
  • Cristian Candela-Juan
  • Jose Luis Loaiza
  • Mar Adria
  • Blanca Ibanez-Rosello
  • Adela Cañete
  • Luis Martí-Bonmatí
  • Alegría Montoro
  • Int. J. Radiat. Biol..2019 03;95(3):314-320. doi: 10.1080/09553002.2019.1549755.Epub 2019-01-11.

硫黄マスタードの皮膚に対する病態生理学的効果と現在の治療法：ファイトケミカルの応用の可能性

Pathophysiological effects of sulfur mustard on skin and its current treatments: possible application of phytochemicals.
  • Mehdi Hassanpour
  • Fateme Hajihassani
  • Mina Abdollahpourasl
  • Omid Cheraghi
  • Nasser Aghamohamadzade
  • Reza Rahbargazi
  • Mohammad Nouri
  • Younes Pilehvar-Soltanahmadi
  • Nosratollah Zarghami
  • Abolfazl Akbarzadeh
  • Yunes Panahi
  • Amirhossein Sahebkar
  • Comb. Chem. High Throughput Screen..2020 Jul;CCHTS-EPUB-108233. doi: 10.2174/1386207323666200717150414.Epub 2020-07-17.

ペアハウジングでは、制御された強化剤の周波数手順を用いずに、アンフェタミンによって誘発されたリスキーな選択の変化に対する確率提示順序の変調効果を減衰させた

Pair housing, but not using a controlled reinforcer frequency procedure, attenuates the modulatory effect of probability presentation order on amphetamine-induced changes in risky choice.
  • Justin R Yates
  • Alexis L Ellis
  • Karson E Evans
  • Joy L Kappesser
  • Kadyn M Lilly
  • Prodiges Mbambu
  • Tanner G Sutphin
  • Behav. Brain Res..2020 Jul;390:112669. S0166-4328(20)30368-5. doi: 10.1016/j.bbr.2020.112669.Epub 2020-05-15.

非環状レチノイドとアンジオテンシンII受容体拮抗薬が糖尿病OLETFラットのジエチルニトロサミン誘発性肝癌化に対して複合的な保護効果を発揮する

Acyclic retinoid and angiotensin-II receptor blocker exert a combined protective effect against diethylnitrosamine-induced hepatocarcinogenesis in diabetic OLETF rats.
  • Norihisa Nishimura
  • Kosuke Kaji
  • Mitsuteru Kitade
  • Yosuke Aihara
  • Shinya Sato
  • Kenichiro Seki
  • Yasuhiko Sawada
  • Hiroaki Takaya
  • Yasushi Okura
  • Hideto Kawaratani
  • Kei Moriya
  • Tadashi Namisaki
  • Akira Mitoro
  • Hitoshi Yoshiji
  • BMC Cancer.2018 Nov;18(1):1164. 10.1186/s12885-018-5099-6. doi: 10.1186/s12885-018-5099-6.Epub 2018-11-26.

オペランド技術を用いて、高性能で安定なアルカリ膜燃料電池を理解し、設計することができます

Using operando techniques to understand and design high performance and stable alkaline membrane fuel cells.
  • Xiong Peng
  • Devashish Kulkarni
  • Ying Huang
  • Travis J Omasta
  • Benjamin Ng
  • Yiwei Zheng
  • Lianqin Wang
  • Jacob M LaManna
  • Daniel S Hussey
  • John R Varcoe
  • Iryna V Zenyuk
  • William E Mustain
  • Nat Commun.2020 Jul;11(1):3561. 10.1038/s41467-020-17370-7. doi: 10.1038/s41467-020-17370-7.Epub 2020-07-16.

ヘリコバクター・ピロリ除菌後の胃がんのリスク層別化．松島諸島における人口ベースの研究

Risk Stratification for Gastric Cancer after Helicobacter pylori Eradication: A Population-based Study on Matsu Islands.
  • Tsung-Hsien Chiang
  • Masahiro Maeda
  • Harumi Yamada
  • Chang-Chuan Chan
  • Sam Li-Sheng Chen
  • Sherry Yueh-Hsia Chiu
  • Yen-Nien Chen
  • Yi-Hsuan Chou
  • Chun-Fu Shieh
  • Cheng-Ying Liu
  • Han-Mo Chiu
  • Hung Chiang
  • Chia-Tung Shun
  • Ming-Wei Lin
  • Ming-Shiang Wu
  • Jaw-Town Lin
  • Chen Hsiu-Hsi
  • Toshikazu Ushijima
  • David Y Graham
  • Yi-Chia Lee
  • J. Gastroenterol. Hepatol..2020 Jul;doi: 10.1111/jgh.15187.Epub 2020-07-15.

サウジアラビアの女子大学の異なる医療従事者の学生を対象に、サウジアラビアのファーマコビジランス制度に関する意識、視点、基礎的な実践能力を比較評価した

The comparative assessment of awareness, perspective, and basic practice skills about the Saudi pharmacovigilance system among students of different health-care professionals of a Saudi Female University.
  • Asmatanzeem Bepari
  • Rasha Assad Assiri
  • Maya Abdullah AlYahya
  • Shaden Jamaan AlGhamdi
  • Amal Mohammed AlGhamdi
  • Afrah Asaad AlOnazi
  • Saudi Pharm J.2020 Jul;28(7):828-836. S1319-0164(20)30120-1. doi: 10.1016/j.jsps.2020.06.002.Epub 2020-06-12.

アンドロゲンジヒドロテストステロン（DHT）は、新たに同定された膜型アンドロゲン受容体（mAR-SLC39A9）を介してGαiタンパク質/MAPK/MMP9の細胞内シグナル伝達を介して、膀胱癌の核内AR陰性細胞浸潤を促進します

Androgen dihydrotestosterone (DHT) promotes the bladder cancer nuclear AR-negative cell invasion via a newly identified membrane androgen receptor (mAR-SLC39A9)-mediated Gαi protein/MAPK/MMP9 intracellular signaling.
  • Jinbo Chen
  • Fuju Chou
  • Shuyuan Yeh
  • Zhenyu Ou
  • Chihrong Shyr
  • Chiping Huang
  • Zhendong Xiang
  • Yin Sun
  • Edward Messing
  • Xiongbing Zu
  • Chawnshang Chang
  • Oncogene.2020 01;39(3):574-586. 10.1038/s41388-019-0964-6. doi: 10.1038/s41388-019-0964-6.Epub 2019-09-10.

パクリタキセル治療を受けた原発性皮膚血管肉腫患者を対象としたパゾパニブの単群確認試験。日本臨床腫瘍グループ試験（JCOG1605、JCOG-PCASプロトコール）

A single-arm confirmatory trial of pazopanib in patients with paclitaxel-pretreated primary cutaneous angiosarcoma: Japan Clinical Oncology Group study (JCOG1605, JCOG-PCAS protocol).
  • Kohei Oashi
  • Taro Shibata
  • Kenjiro Namikawa
  • Akira Takahashi
  • Kenji Yokota
  • Eiji Nakano
  • Yukiko Teramoto
  • Arata Tsutsumida
  • Taku Maeda
  • Naoya Yamazaki
  • BMC Cancer.2020 Jul;20(1):652. 10.1186/s12885-020-07136-1. doi: 10.1186/s12885-020-07136-1.Epub 2020-07-13.

網膜の健康と変性における小・中細胞外ベシクルとそのmiRNAカーゴ。網膜の恒常性維持のメディエーター、標的遺伝子治療のためのビークル

Small-Medium Extracellular Vesicles and Their miRNA Cargo in Retinal Health and Degeneration: Mediators of Homeostasis, and Vehicles for Targeted Gene Therapy.
  • Yvette Wooff
  • Adrian V Cioanca
  • Joshua A Chu-Tan
  • Riemke Aggio-Bruce
  • Ulrike Schumann
  • Riccardo Natoli
  • Front Cell Neurosci.2020;14:160. doi: 10.3389/fncel.2020.00160.Epub 2020-06-25.

コロンビアの和平合意から 1 年後の訓練と社会復帰のための領土空間における保健サービスへの効果的なアクセスの知覚：横断的研究

Perception of effective access to health services in Territorial Spaces for Training and Reintegration, one year after the peace accords in Colombia: a cross-sectional study.
  • Julián Alfredo Fernández-Niño
  • Lud Magdy Chavarro
  • Ana Beatriz Vásquez-Rodríguez
  • Maylen Liseth Rojas-Botero
  • Ginna Esmeralda Hernández-Neuta
  • Ana Maria Peñuela-Poveda
  • David Alejandro Rodríguez
  • F1000Res.2019;8:2140. doi: 10.12688/f1000research.21375.1.Epub 2019-12-23.

ウォルフ-パーキンソン-ホワイト症候群の小児患者におけるセプタル経路のスクリーニングに焦点を当てた付属経路局在化のための新しいアルゴリズム

New Algorithm for Accessory Pathway Localization Focused on Screening Septal Pathways in Pediatric Patients with Wolff-Parkinson-White Syndrome.
  • Seung Min Baek
  • Mi Kyoung Song
  • Jae-Sun Uhm
  • Gi Beom Kim
  • Eun Jung Bae
  • Heart Rhythm.2020 Jul;S1547-5271(20)30671-8. doi: 10.1016/j.hrthm.2020.07.016.Epub 2020-07-15.

天然アルカロイドであるベルベリンのピリジン誘導体をヒトのテロメリックG-DNAバインダーとして利用した研究」の訂正。溶液および固体状態の研究"を掲載しました

Correction to "Pyridine Derivative of the Natural Alkaloid Berberine as Human Telomeric G-DNA Binder: A Solution and Solid-State Study".
  • Francesco Papi
  • Carla Bazzicalupi
  • Marta Ferraroni
  • Giulia Ciolli
  • Paolo Lombardi
  • Asma Yasmeen Khan
  • Gopinatha Suresh Kumar
  • Paola Gratteri
  • ACS Med Chem Lett.2020 Jul;11(7):1490. doi: 10.1021/acsmedchemlett.0c00309.Epub 2020-06-22.

ブラックルクオリーブは、ラットの卵巣摘出術による骨量減少とタルク肉芽腫症を予防した

Black Lucques olives prevented bone loss caused by ovariectomy and talc granulomatosis in rats.
  • Caroline Puel
  • Julie Mardon
  • Séraphin Kati-Coulibaly
  • Marie-Jeanne Davicco
  • Patrice Lebecque
  • Christiane Obled
  • Edmond Rock
  • Marie-Noelle Horcajada
  • Apostolos Agalias
  • Leandros A Skaltsounis
  • Véronique Coxam
  • Br. J. Nutr..2007 May;97(5):1012-20. S0007114507659030. doi: 10.1017/S0007114507659030.

太陽の下でのストレス。海産二枚貝のフィルターフィーダーであるマニラアサリのRuditapes philippinarumにおける低濃度UVフィルター4-メチルベンジリデンカンファー（4-MBC）への曝露の影響

Stress under the sun: Effects of exposure to low concentrations of UV-filter 4- methylbenzylidene camphor (4-MBC) in a marine bivalve filter feeder, the Manila clam Ruditapes philippinarum.
  • Melania Santonocito
  • Barbara Salerno
  • Chiara Trombini
  • Federico Tonini
  • Marina G Pintado-Herrera
  • Gonzálo Martínez-Rodríguez
  • Julián Blasco
  • Pablo Antonio Lara-Martín
  • Miriam Hampel
  • Aquat. Toxicol..2020 Apr;221:105418. S0166-445X(19)30894-X. doi: 10.1016/j.aquatox.2020.105418.Epub 2020-02-03.

コンゴ民主共和国のマランガ（キンペーゼ）睡眠病フォーカスのツェツェバエの中腸における異なるトリパノソーマ種の同定

Identification of different trypanosome species in the mid-guts of tsetse flies of the Malanga (Kimpese) sleeping sickness focus of the Democratic Republic of Congo.
  • Gustave Simo
  • Barberine Silatsa
  • Njiokou Flobert
  • Pascal Lutumba
  • Philemon Mansinsa
  • Joule Madinga
  • Emile Manzambi
  • Reginald De Deken
  • Tazoacha Asonganyi
  • Parasit Vectors.2012 Sep;5:201. 1756-3305-5-201. doi: 10.1186/1756-3305-5-201.Epub 2012-09-19.

抗線溶性部位特異的ファーマコレーザー治療によるポートワインの汚れの治療のための熱感受性リポソームのインビボ評価

In Vivo Assessment of Thermosensitive Liposomes for the Treatment of Port Wine Stains by Antifibrinolytic Site-Specific Pharmaco-Laser Therapy.
  • Mingjuan Li
  • M Ingmar van Raath
  • Shervin Khakpour
  • Ahmet Seçilir
  • Bart C Sliggers
  • Xuan Huang
  • Baoyue Ding
  • Gert Storm
  • René R van der Hulst
  • Anton I P M de Kroon
  • Michal Heger
  • Pharmaceutics.2020 Jun;12(6). E591. doi: 10.3390/pharmaceutics12060591.Epub 2020-06-25.

硝酸ナトリウム処理ラットにおけるJ.carnae葉抽出物の血球保護作用および赤血球膜安定化作用

Haematoprotective and red blood cell membrane stabilizing effects of Justicia carnae leaf extracts in sodium nitrate-treated rats.
  • Eberechukwu Mbanaso
  • Azubuike Nwankwo
  • Solomon Nnah Ijioma
  • Okezie Emmanuel
  • Eziuche Amadike Ugbogu
  • Ngozi Nwagbara
  • Kingsley Ugwuanyi
  • J Basic Clin Physiol Pharmacol.2020 Jul;/j/jbcpp.ahead-of-print/jbcpp-2019-0275/jbcpp-2019-0275.xml. doi: 10.1515/jbcpp-2019-0275.Epub 2020-07-13.

ヒトコレクトリン-11（COLEC11）とそのMASP2との相乗的な遺伝的相互作用は、シャーガス病の病態生理に関連しています

Human collectin-11 (COLEC11) and its synergic genetic interaction with MASP2 are associated with the pathophysiology of Chagas Disease.
  • Thaisa Lucas Sandri
  • Fabiana Antunes Andrade
  • Kárita Cláudia Freitas Lidani
  • Elias Einig
  • Angelica Beate Winter Boldt
  • Benjamin Mordmüller
  • Meral Esen
  • Iara J Messias-Reason
  • PLoS Negl Trop Dis.2019 04;13(4):e0007324. PNTD-D-18-01714. doi: 10.1371/journal.pntd.0007324.Epub 2019-04-17.

黒胡椒由来のアルカロイドはNF-κB経路の活性化を阻害することにより、マウスマクロファージにおける抗炎症活性を示します

Alkaloids from Black Pepper ( L.) Exhibit Anti-Inflammatory Activity in Murine Macrophages by Inhibiting Activation of NF-κB Pathway.
  • Heying Pei
  • Linlin Xue
  • Minghai Tang
  • Huan Tang
  • Shuang Kuang
  • Lun Wang
  • Xu Ma
  • Xiaoying Cai
  • Yan Li
  • Min Zhao
  • Aihua Peng
  • Haoyu Ye
  • Lijuan Chen
  • J. Agric. Food Chem..2020 Feb;68(8):2406-2417. doi: 10.1021/acs.jafc.9b07754.Epub 2020-02-18.

一半球の可塑性、二半球からの制御：新生児ラットの片側皮質脊髄損傷後の下降運動経路の適応性

Plasticity in One Hemisphere, Control From Two: Adaptation in Descending Motor Pathways After Unilateral Corticospinal Injury in Neonatal Rats.
  • Tong-Chun Wen
  • Sophia Lall
  • Corey Pagnotta
  • James Markward
  • Disha Gupta
  • Shivakeshavan Ratnadurai-Giridharan
  • Jacqueline Bucci
  • Lucy Greenwald
  • Madelyn Klugman
  • N Jeremy Hill
  • Jason B Carmel
  • Front Neural Circuits.2018;12:28. doi: 10.3389/fncir.2018.00028.Epub 2018-04-12.

サフィナミドの覚醒剤誘発性神経変性に対する神経保護作用と神経生存能。BDNF/TrkB/PGC-1αシグナル伝達経路とミトコンドリアアンカップリングプロテイン-2(UCP-2)の役割の仮説的可能性

Neuroprotective and neuro-survival properties of safinamide against methamphetamine-induced neurodegeneration: Hypothetic possible role of BDNF/TrkB/PGC-1α signaling pathway and mitochondrial uncoupling protein -2(UCP-2).
  • Afrah Sepehr
  • Fereshteh Taheri
  • Sara Heidarian
  • Majid Motaghinejad
  • Sepideh Safari
  • Med. Hypotheses.2020 Jul;143:110094. S0306-9877(20)30442-4. doi: 10.1016/j.mehy.2020.110094.Epub 2020-07-11.

甲状腺転写因子1（TTF-1）陰性、EGFR/ALK陰性の肺腺がんにおけるペメトレキセドベースの化学療法は、ペメトレキセドを含まないレジメンよりも劣る：傾向スコアマッチドペア分析

Pemetrexed-Based Chemotherapy Is Inferior to Pemetrexed-Free Regimens in Thyroid Transcription Factor 1 (TTF-1)-Negative, EGFR/ALK-Negative Lung Adenocarcinoma: A Propensity Score Matched Pairs Analysis.
  • Nikolaj Frost
  • Tamar Zhamurashvili
  • Maximilian von Laffert
  • Frederick Klauschen
  • Christoph Ruwwe-Glösenkamp
  • Matthias Raspe
  • Matthias Brunn
  • Sebastian Ochsenreither
  • Bettina Temmesfeld-Wollbrück
  • Norbert Suttorp
  • Christian Grohé
  • Martin Witzenrath
  • Clin Lung Cancer.2020 May;S1525-7304(20)30154-6. doi: 10.1016/j.cllc.2020.05.014.Epub 2020-05-22.

ミクログリアの活性化を調節することで、歯状回におけるアルギナーゼ1を介した母体免疫活性化による統合失調症関連行動の表現型を防ぐことができる

Modulating microglia activation prevents maternal immune activation induced schizophrenia-relevant behavior phenotypes via arginase 1 in the dentate gyrus.
  • Yucen Xia
  • Zhiqing Zhang
  • Weipeng Lin
  • Jinglan Yan
  • Chuan'an Zhu
  • Dongmin Yin
  • Su He
  • Yang Su
  • Nenggui Xu
  • Robert William Caldwell
  • Lin Yao
  • Yongjun Chen
  • Neuropsychopharmacology.2020 Jun;10.1038/s41386-020-0743-7. doi: 10.1038/s41386-020-0743-7.Epub 2020-06-29.

インド・ベンガルールの農村と都市の界面における野縁植生の構造と構成：農業生態系の未踏の側面に関する事例研究

Structure and composition of field margin vegetation in the rural-urban interface of Bengaluru, India: a case study on an unexplored dimension of agroecosystems.
  • Sunil Nautiyal
  • Mrinalini Goswami
  • Rama Rao Nidamanuri
  • Ellen M Hoffmann
  • Andreas Buerkert
  • Environ Monit Assess.2020 Jul;192(8):520. 10.1007/s10661-020-08428-6. doi: 10.1007/s10661-020-08428-6.Epub 2020-07-15.

人工河川の底生無脊椎動物および生態系機能に及ぼす有機UVフィルター3-(4-メチルベンジリデン)樟脳の効果（英文

Effects of the organic UV-filter, 3-(4-methylbenzylidene) camphor, on benthic invertebrates and ecosystem function in artificial streams.
  • Diana Campos
  • Ana L Machado
  • Diogo N Cardoso
  • Ana Rita R Silva
  • Patrícia V Silva
  • Andreia C M Rodrigues
  • Fátima C P Simão
  • Susana Loureiro
  • Kateřina Grabicová
  • Petra Nováková
  • Amadeu M V M Soares
  • João L T Pestana
  • Environ. Pollut..2020 May;260:113981. S0269-7491(19)36601-1. doi: 10.1016/j.envpol.2020.113981.Epub 2020-01-13.

肥満成人のスリーブ胃切除術後1年後の完全寛解および部分寛解、改善、または糖尿病状態の変化なしと関連する因子

Factors associated with complete and partial remission, improvement, or unchanged diabetes status of obese adults 1 year after sleeve gastrectomy.
  • Isra Elgenaied
  • Walid El Ansari
  • Mohamed Aly Elsherif
  • Sama Abdulrazzaq
  • Amjad Salah Qabbani
  • Wahiba Elhag
  • Surg Obes Relat Dis.2020 May;S1550-7289(20)30271-9. doi: 10.1016/j.soard.2020.05.013.Epub 2020-05-27.

Dioscorea tokoro Makino ex Miyabe に含まれるトコロニンは、古典的 MAPK パスウェイ活性化の抑制を介して B16 細胞のα-MSH 誘導メラニン生成を抑制した

Tokoronin Contained in Dioscorea tokoro Makino ex Miyabe Suppressed α-MSH-Induced Melanogenesis in B16 Cells via Suppression of Classical MAPK Pathway Activation.
  • Motohiko Ukiya
  • Daisuke Sato
  • Hirokazu Kimura
  • Yasuaki Hirai
  • Atsuyoshi Nishina
  • Chem. Biodivers..2020 Jun;17(6):e2000077. doi: 10.1002/cbdv.202000077.Epub 2020-05-07.

TBK1 と IKKε は、ミエロイド細胞における STING 誘導 NF-κB 応答を媒介するために冗長に作用します

TBK1 and IKKε Act Redundantly to Mediate STING-Induced NF-κB Responses in Myeloid Cells.
  • Katherine R Balka
  • Cynthia Louis
  • Tahnee L Saunders
  • Amber M Smith
  • Dale J Calleja
  • Damian B D'Silva
  • Fiona Moghaddas
  • Maximilien Tailler
  • Kate E Lawlor
  • Yifan Zhan
  • Christopher J Burns
  • Ian P Wicks
  • Jonathan J Miner
  • Benjamin T Kile
  • Seth L Masters
  • Dominic De Nardo
  • Cell Rep.2020 Apr;31(1):107492. S2211-1247(20)30370-3. doi: 10.1016/j.celrep.2020.03.056.

片頭痛患者の甲状腺機能に関連するホルモンレベルを報告した最近の研究のシステマティックレビューおよびメタアナリシスを、2020年4月までに実施した

A systematic review and meta-analysis of recent studies reporting hormone levels related to thyroid gland function in migraineurs, until April 2020.
  • Ali Seidkhani-Nahal
  • Asad Mirzaei
  • Gholam Basati
  • Davoud Parvizi-Faraz
  • Ali Noori-Zadeh
  • Hormones (Athens).2020 Jul;10.1007/s42000-020-00228-4. doi: 10.1007/s42000-020-00228-4.Epub 2020-07-15.

グルタミン制限下で選択されたチャイニーズハムスター卵巣細胞における過剰なグルタミン合成酵素活性は、グルタミン不足条件下では成長制限的であり、セリンによって阻害される可能性がある

Superfluous glutamine synthetase activity in Chinese Hamster Ovary cells selected under glutamine limitation is growth limiting in glutamine-replete conditions and can be inhibited by serine.
  • Vishwanathgouda Maralingannavar
  • Dharmeshkumar Parmar
  • Venkateswarlu Panchagnula
  • Mugdha Gadgil
  • Biotechnol. Prog..2019 09;35(5):e2856. doi: 10.1002/btpr.2856.Epub 2019-06-12.

ヒト臍帯多能性間葉系間葉系間葉系間質細胞は、炎症反応や酸化ストレスを軽減することで、精子形成細胞の急性虚血再灌流障害を緩和することがわかった

Human umbilical cord multipotent mesenchymal stromal cells alleviate acute ischemia-reperfusion injury of spermatogenic cells via reducing inflammatory response and oxidative stress.
  • Liang Zhong
  • Mengbo Yang
  • Xiangyu Zou
  • Tao Du
  • Huiming Xu
  • Jie Sun
  • Stem Cell Res Ther.2020 Jul;11(1):294. 10.1186/s13287-020-01813-5. doi: 10.1186/s13287-020-01813-5.Epub 2020-07-17.

転移性大腸がん患者の予後評価のための無細胞全DNA、カルチノエンブリオニック抗原、C反応性タンパク質

Total cell-free DNA, carcinoembryonic antigen, and C-reactive protein for assessment of prognosis in patients with metastatic colorectal cancer.
  • Karen-Lise Garm Spindler
  • Christina Demuth
  • Boe Sandahl Sorensen
  • Julia S Johansen
  • Dorte Nielsen
  • Niels Pallisgaard
  • Estrid Hoegdall
  • Per Pfeiffer
  • Benny Vittrup Jensen
  • Tumour Biol..2018 Nov;40(11):1010428318811207. doi: 10.1177/1010428318811207.

高プロラクチン血症は、橋本甲状腺炎患者の甲状腺自己免疫に対するビタミンD/セレノメチオニン併用療法の抑制効果を減少させる。試験的研究

Hyperprolactinaemia attenuates the inhibitory effect of vitamin D/selenomethionine combination therapy on thyroid autoimmunity in euthyroid women with Hashimoto's thyroiditis: A pilot study.
  • Robert Krysiak
  • Karolina Kowalcze
  • Bogusław Okopień
  • J Clin Pharm Ther.2020 Jul;doi: 10.1111/jcpt.13214.Epub 2020-07-10.

動的光による光合成の抑制は、窒素欠乏条件下では、十分な窒素供給条件下よりも、ダイズの方がより少なく、むしろ多くなった

Dynamic light caused less photosynthetic suppression, rather than more, under nitrogen deficit conditions than under sufficient nitrogen supply conditions in soybean.
  • Yu-Ting Li
  • Ying Li
  • Yue-Nan Li
  • Ying Liang
  • Qiang Sun
  • Geng Li
  • Peng Liu
  • Zi-Shan Zhang
  • Hui-Yuan Gao
  • BMC Plant Biol..2020 Jul;20(1):339. 10.1186/s12870-020-02516-y. doi: 10.1186/s12870-020-02516-y.Epub 2020-07-17.

冠動脈CT造影における低ヨード濃度造影を用いた低管電圧プロトコルと高管電圧プロトコルを用いた高ヨード濃度造影の実現可能性を比較した

Comparing feasibility of low-tube-voltage protocol with low-iodine-concentration contrast and high-tube-voltage protocol with high-iodine-concentration contrast in coronary computed tomography angiography.
  • Min Jae Cha
  • Sung Mok Kim
  • Tae Ran Ahn
  • Yeon Hyeon Choe
  • PLoS ONE.2020;15(7):e0236108. PONE-D-20-04325. doi: 10.1371/journal.pone.0236108.Epub 2020-07-16.

PRRSV-1の病原菌Lena株感染の急性期における肺組織傷害におけるプロおよび抗炎症反応の活性化

Activation of pro- and anti-inflammatory responses in lung tissue injury during the acute phase of PRRSV-1 infection with the virulent strain Lena.
  • J M Sánchez-Carvajal
  • I M Rodríguez-Gómez
  • I Ruedas-Torres
  • F Larenas-Muñoz
  • I Díaz
  • C Revilla
  • E Mateu
  • J Domínguez
  • G Martín-Valls
  • I Barranco
  • F J Pallarés
  • L Carrasco
  • J Gómez-Laguna
  • Vet. Microbiol..2020 Jul;246:108744. S0378-1135(20)30433-8. doi: 10.1016/j.vetmic.2020.108744.Epub 2020-06-02.

HMGB1の酸性尾部は、その二次構造とコンフォメーションの柔軟性を制御している。円形二色性と分子動力学シミュレーションによる研究

The acidic tail of HMGB1 regulates its secondary structure and conformational flexibility: A circular dichroism and molecular dynamics simulation study.
  • Wresti L Anggayasti
  • Kenta Ogino
  • Eiji Yamamoto
  • Erik Helmerhorst
  • Kenji Yasuoka
  • Ricardo L Mancera
  • Comput Struct Biotechnol J.2020;18:1160-1172. S2001-0370(20)30275-0. doi: 10.1016/j.csbj.2020.05.012.Epub 2020-05-16.

Toll-like receptor 7-adapter complexはHIV刺激を受けた形質細胞性樹状細胞におけるインターフェロン-α産生を調節している

Toll-like receptor 7-adapter complex modulates interferon-α production in HIV-stimulated plasmacytoid dendritic cells.
  • Andy A Patamawenu
  • Nathaniel E Wright
  • Tulley Shofner
  • Sean Evans
  • Maura M Manion
  • Nicole Doria-Rose
  • Stephen A Migueles
  • Daniel Mendoza
  • Bennett Peterson
  • Christopher Wilhelm
  • Julia Rood
  • Amy Berkley
  • Nancy A Cogliano
  • C Jason Liang
  • Kiki Tesselaar
  • Frank Miedema
  • Julian Bess
  • Jeffrey Lifson
  • Mark Connors
  • PLoS ONE.2019;14(12):e0225806. PONE-D-19-21147. doi: 10.1371/journal.pone.0225806.Epub 2019-12-12.

未分割ヘパリンはホスファチジルイノシトール-3キナーゼ/セリン/スレオニンキナーゼ/核因子κ-B経路を介して内皮バリア機能障害を減衰させる

Unfractionated heparin attenuates endothelial barrier dysfunction via the phosphatidylinositol-3 kinase/serine/threonine kinase/nuclear factor kappa-B pathway.
  • Sheng-Tian Mu
  • Jie Tang
  • Jian-Qi Ma
  • Yu Zhong
  • Han-Zhe Liu
  • Xiao-Chun Ma
  • Zhen Zheng
  • Chin. Med. J..2020 Jul;doi: 10.1097/CM9.0000000000000905.Epub 2020-07-01.

パリ郊外の大学病院における COVID-19 を示唆する症状を持つ医療従事者の間での SARS-CoV-2 の鼻咽頭感染

[Nasopharyngeal carriage of SARS-CoV-2 among health personnel with symptoms suggestive of COVID-19 in a University Hospital in the Paris suburbs].
  • S Greffe
  • F Espinasse
  • C Duran
  • S Labrune
  • M Sirol
  • B Mantalvan
  • M C Gramer
  • C Babulle
  • G Do Rosario
  • Q Vauvillier
  • A Huet
  • A Van der Heidjen
  • J Tysebaert
  • L F Kramarz
  • J-P Rabes
  • G Pellissier
  • T Chinet
  • F Moreau
  • E Rouveix
  • Rev Med Interne.2020 Jul;S0248-8663(20)30243-5. doi: 10.1016/j.revmed.2020.06.017.Epub 2020-07-08.

COVID-19がブラジルの泌尿器科医の臨床実践、収入、健康、生活行動に与えた影響

Impact of COVID-19 on clinical practice, income, health and lifestyle behavior of Brazilian urologists.
  • Cristiano M Gomes
  • Luciano A Favorito
  • João Victor T Henriques
  • Alfredo F Canalini
  • Karin M J Anzolch
  • Roni de Carvalho Fernandes
  • Carlos H S Bellucci
  • Caroline S Silva
  • Marcelo L Wroclawski
  • Antonio Carlos L Pompeo
  • José de Bessa
  • Int Braz J Urol.2020 Jun;46. IBJU20209915. doi: 10.1590/S1677-5538.IBJU.2020.99.15.Epub 2020-06-05.

新規タンパク質恒常性モジュレーターBTX306は骨髄腫で活性を示し、ボルテゾミブとレナリドミドマイドの耐性を克服している

The novel protein homeostatic modulator BTX306 is active in myeloma and overcomes bortezomib and lenalidomide resistance.
  • Jianxuan Zou
  • Richard J Jones
  • Hua Wang
  • Isere Kuiatse
  • Fazal Shirazi
  • Elisabet E Manasanch
  • Hans C Lee
  • Robert Sullivan
  • Leah Fung
  • Normand Richard
  • Paul Erdman
  • Eduardo Torres
  • David Hecht
  • Imelda Lam
  • Brooke McElwee
  • Aparajita H Chourasia
  • Kyle W H Chan
  • Frank Mercurio
  • David I Stirling
  • Robert Z Orlowski
  • J. Mol. Med..2020 Jul;10.1007/s00109-020-01943-6. doi: 10.1007/s00109-020-01943-6.Epub 2020-07-06.

介護施設の入所者および職員における SARS-CoV-2 の無症状感染。リアルタイムPCRおよび血清学的検査の結果

Presymptomatic Transmission of SARS-CoV-2 Amongst Residents and Staff at a Skilled Nursing Facility: Results of Real-Time PCR and Serologic Testing.
  • Scott A Goldberg
  • Jochen Lennerz
  • Michael Klompas
  • Eden Mark
  • Virginia M Pierce
  • Ryan W Thompson
  • Charles T Pu
  • Lauren L Ritterhouse
  • Anand Dighe
  • Eric S Rosenberg
  • David C Grabowski
  • Clin. Infect. Dis..2020 Jul;ciaa991. doi: 10.1093/cid/ciaa991.Epub 2020-07-15.

犬モデルにおける内側コンパートメント性関節症の治療に骨軟骨移植とメニスカル移植が有効であることを明らかにしました

Unicompartmental Bipolar Osteochondral and Meniscal Allograft Transplantation is Effective for Treatment of Medial Compartment Gonarthrosis in a Canine Model.
  • Anna J Schreiner
  • James P Stannard
  • Aaron M Stoker
  • Chantelle C Bozynski
  • Keiichi Kuroki
  • Cristi R Cook
  • James L Cook
  • J. Orthop. Res..2020 Jul;doi: 10.1002/jor.24801.Epub 2020-07-16.

ブラジル南東部のシュガーローフ・ランド：低地のインセルバーグ植物の多様性の熱帯のホットスポット

Sugarloaf Land in south-eastern Brazil: a tropical hotspot of lowland inselberg plant diversity.
  • Luiza F A de Paula
  • Luísa O Azevedo
  • Luana Paula Mauad
  • Leandro Jorge Telles Cardoso
  • João Marcelo Alvarenga Braga
  • Ludovic J C Kollmann
  • Claudio N Fraga
  • Luiz Menini Neto
  • Paulo H Labiak
  • Renato Mello-Silva
  • Stefan Porembski
  • Rafaela Campostrini Forzza
  • Biodivers Data J.2020;8:e53135. 53135. doi: 10.3897/BDJ.8.e53135.Epub 2020-06-19.

COVID-19時代の外科的がん診療：最前線の見解とコンセンサス．

Surgical cancer care in the COVID-19 era: front line views and consensus.
  • Rodrigo Nascimento Pinheiro
  • Felipe J F Coimbra
  • Wilson Luiz DA Costa-Jr
  • Heber Salvador DE Castro Ribeiro
  • Reitan Ribeiro
  • Alberto Julius Alves Wainstein
  • Gustavo Andreazza Laporte
  • Manoel Jesus Pinheiro Coelho-Jr
  • Paulo Henrique DE Sousa Fernandes
  • Eduardo Zanella Cordeiro
  • Bruno JosÉ Queiroz Sarmento
  • Marco Antonio C Guimaraes-Filho
  • Marciano Anghinoni
  • Glauco Baiocchi
  • Alexandre Ferreira Oliveira
  • Rev Col Bras Cir.2020;47:e20202601. S0100-69912020000100181. doi: 10.1590/0100-6991e-20202601.Epub 2020-07-03.

パーム油工場排水から分離された細菌株を用いたバイオ凝集剤の製造方法とその水からのエリオクロームブラックT色素の除去への応用

Bioflocculants Produced by Bacterial Strains Isolated from Palm Oil Mill Effluent for Application in the Removal of Eriochrome Black T Dye from Water.
  • Syed Zaghum Abbas
  • Yang-Chun Yong
  • Moonis Ali Khan
  • Masoom Raza Siddiqui
  • Afnan Ali Hussain Hakami
  • Shareefa Ahmed Alshareef
  • Marta Otero
  • Mohd Rafatullah
  • Polymers (Basel).2020 Jul;12(7). E1545. doi: 10.3390/polym12071545.Epub 2020-07-13.

左心低形成症候群に関連した頭部ドメイン変異を有する誘導多能性幹細胞心筋細胞の収縮性

Contractility of Induced Pluripotent Stem Cell-Cardiomyocytes With an Head Domain Variant Associated With Hypoplastic Left Heart Syndrome.
  • Min-Su Kim
  • Brandon Fleres
  • Jerrell Lovett
  • Melissa Anfinson
  • Sai Suma K Samudrala
  • Lauren J Kelly
  • Laura E Teigen
  • Matthew Cavanaugh
  • Maribel Marquez
  • Aron M Geurts
  • John W Lough
  • Michael E Mitchell
  • Robert H Fitts
  • Aoy Tomita-Mitchell
  • Front Cell Dev Biol.2020;8:440. doi: 10.3389/fcell.2020.00440.Epub 2020-06-23.

ペリリルアルコールとクエルセチンは、PARP1を介したmiR-204のダウンレギュレーションとそのダウンストリーム経路を介して、ラットのモノクロタリン誘発性肺動脈高血圧を改善した

Perillyle alcohol and Quercetin ameliorate monocrotaline-induced pulmonary artery hypertension in rats through PARP1-mediated miR-204 down-regulation and its downstream pathway.
  • Soodeh Rajabi
  • Hamid Najafipour
  • Saeideh Jafarinejad Farsangi
  • Siyavash Joukar
  • Ahmad Beik
  • Maryam Iranpour
  • Zeinab Kordestani
  • BMC Complement Med Ther.2020 Jul;20(1):218. 10.1186/s12906-020-03015-1. doi: 10.1186/s12906-020-03015-1.Epub 2020-07-13.

アルストローム症候群患者におけるPBI-4050による治療：第2相、単施設、単群、非盲検試験の試験プロトコール

Treatment with PBI-4050 in patients with Alström syndrome: study protocol for a phase 2, single-Centre, single-arm, open-label trial.
  • Shanat Baig
  • Vishy Veeranna
  • Shaun Bolton
  • Nicola Edwards
  • Jeremy W Tomlinson
  • Konstantinos Manolopoulos
  • John Moran
  • Richard P Steeds
  • Tarekegn Geberhiwot
  • BMC Endocr Disord.2018 Nov;18(1):88. 10.1186/s12902-018-0315-6. doi: 10.1186/s12902-018-0315-6.Epub 2018-11-26.

健康なボランティアの血清サイトカイン濃度に対するプロポフォールとデクスメデトミジンの効果（レミフェンタニルの有無にかかわらず）：ポストホック分析

Effects of propofol and dexmedetomidine with and without remifentanil on serum cytokine concentrations in healthy volunteers: a post hoc analysis.
  • Dirk J Bosch
  • Matijs V Meurs
  • Rianne M Jongman
  • Peter Heeringa
  • Wayel H Abdulahad
  • Michel M R F Struys
  • Br J Anaesth.2020 Jul;S0007-0912(20)30421-9. doi: 10.1016/j.bja.2020.05.039.Epub 2020-07-10.

デクスメデトミジンは、カンナビノイド受容体2のアップレギュレーションにより、腸虚血/再灌流により誘発される肺障害を改善し、その後、ホスファチジルイノシトール3-キナーゼ/Akt経路の活性化を促進します

Dexmedetomidine Ameliorates Lung Injury Induced by Intestinal Ischemia/Reperfusion by Upregulating Cannabinoid Receptor 2, Followed by the Activation of the Phosphatidylinositol 3-Kinase/Akt Pathway.
  • Meng Chen
  • Xue-Tao Yan
  • Li Ye
  • Jun-Jiao Tang
  • Zong-Ze Zhang
  • Xiang-Hu He
  • Oxid Med Cell Longev.2020;2020:6120194. doi: 10.1155/2020/6120194.Epub 2020-06-21.

先天性内側直腸低形成症による大角度外反症の治療のための最小侵襲性垂直筋移植術：症例報告と文献レビュー

Minimal invasive vertical muscle transposition for the treatment of large angle exotropia due to congenital medial rectus hypoplasia: Case Report and Literature Review.
  • Mohammad Yaser Kiarudi
  • Aliakbar Sabermoghadam
  • Mahsa Sardabi
  • Seyed Vahid Jafarzadeh
  • Mohammad Etezad Razavi
  • Strabismus.2020 Jul;:1-5. doi: 10.1080/09273972.2020.1779320.Epub 2020-07-02.

ニューヨーク市の小児病院におけるコロナウイルス疾患 2019（COVID-19）患者の疫学、臨床的特徴、および疾患の重症度

Epidemiology, Clinical Features, and Disease Severity in Patients With Coronavirus Disease 2019 (COVID-19) in a Children's Hospital in New York City, New York.
  • Philip Zachariah
  • Candace L Johnson
  • Katia C Halabi
  • Danielle Ahn
  • Anita I Sen
  • Avital Fischer
  • Sumeet L Banker
  • Mirna Giordano
  • Christina S Manice
  • Rebekah Diamond
  • Taylor B Sewell
  • Adam J Schweickert
  • John R Babineau
  • R Colin Carter
  • Daniel B Fenster
  • Jordan S Orange
  • Teresa A McCann
  • Steven G Kernie
  • Lisa Saiman
  • JAMA Pediatr.2020 06;:e202430. 2766920. doi: 10.1001/jamapediatrics.2020.2430.Epub 2020-06-03.

FIGO分類2018。化学放射線治療を受けた局所進行子宮頸がん患者を対象とした検証試験

FIGO classification 2018: Validation study in patients with locally advanced cervix cancer treated with chemo-radiation.
  • Atul Raut
  • Supriya Chopra
  • Prachi Mittal
  • Gayatri Patil
  • Umesh Mahantshetty
  • Lavanya Gurram
  • Jamema Swamidas
  • Jaya Ghosh
  • Seema Gulia
  • Palak Popat
  • Kedar Deodhar
  • Amita Maheshwari
  • Sudeep Gupta
  • Int. J. Radiat. Oncol. Biol. Phys..2020 Jul;S0360-3016(20)31418-8. doi: 10.1016/j.ijrobp.2020.07.020.Epub 2020-07-15.

遺伝性血栓症または既往のVTEを持つ女性に特に焦点を当てた妊娠中および周産期における静脈血栓塞栓症の予防-血栓症・止血学会（GTH）の女性の健康に関するワーキンググループの論文

Prevention of Venous Thromboembolism during Pregnancy and the Puerperium with a Special Focus on Women with Hereditary Thrombophilia or Prior VTE-Position Paper of the Working Group in Women's Health of the Society of Thrombosis and Haemostasis (GTH).
  • Christina Hart
  • Rupert Bauersachs
  • Ute Scholz
  • Rainer Zotz
  • Frauke Bergmann
  • Hannelore Rott
  • Birgit Linnemann
  • Hamostaseologie.2020 Jun;doi: 10.1055/a-1132-0750.Epub 2020-06-26.

誘導組織再生および誘導骨再生における成長因子を豊富に含む血漿（PRGF）の使用。ヒトにおける組織学的、免疫組織化学的、組織形態学的、放射線学的、臨床的結果のレビュー

The use of plasma rich in growth factors (PRGF) in guided tissue regeneration and guided bone regeneration. A review of histological, immunohistochemical, histomorphometrical, radiological and clinical results in humans.
  • Önder Solakoglu
  • Guido Heydecke
  • Niusha Amiri
  • Eduardo Anitua
  • Ann. Anat..2020 May;231:151528. S0940-9602(20)30072-8. doi: 10.1016/j.aanat.2020.151528.Epub 2020-05-04.

COVID-19パンデミックがプライマリーケアの中核的機能に及ぼす影響：治療は病気よりも悪化するのか？フランドル地方の開業医を対象とした質的インタビュー研究

Impact of the COVID-19 pandemic on the core functions of primary care: will the cure be worse than the disease? A qualitative interview study in Flemish GPs.
  • Veronique Verhoeven
  • Giannoula Tsakitzidis
  • Hilde Philips
  • Paul Van Royen
  • BMJ Open.2020 06;10(6):e039674. bmjopen-2020-039674. doi: 10.1136/bmjopen-2020-039674.Epub 2020-06-17.

インダカテロール/グリコピロニウム・チオトロピウムを用いた COPD 患者の 3 分間の等速シャトル試験中の労作性呼吸困難の緩和：RED 試験

Relieving exertional dyspnea during the 3-min constant speed shuttle test in patients with COPD with indacaterol/glycopyrronium tiotropium: the RED trial.
  • Jessie Beaulieu
  • Dennis Jensen
  • Denis E O'Donnell
  • Cynthia Brouillard
  • Lauren Tracey
  • Sandra Vincent
  • Éric Nadreau
  • Emmanuelle Bernard
  • Sarah Bernard
  • François Maltais
  • Ther Adv Respir Dis.2020 Jan-Dec;14:1753466620939507. doi: 10.1177/1753466620939507.

インドにおけるコロナウイルス感染症19（COVID-19）患者における胸部コンピュータ断層撮影（CT）所見のスペクトル

Spectrum of chest computed tomographic (CT) findings in coronavirus disease-19 (COVID-19) patients in India.
  • Arshed Hussain Parry
  • Abdul Haseeb Wani
  • Mudasira Yaseen
  • Khurshid Ahmad Dar
  • Naseer Ahmad Choh
  • Naseer Ahmad Khan
  • Naveed Nazir Shah
  • Majid Jehangir
  • Eur J Radiol.2020 Aug;129:109147. S0720-048X(20)30336-3. doi: 10.1016/j.ejrad.2020.109147.Epub 2020-06-24.

ミツバチプロポリスの有効成分であるカフェイン酸フェネチルエステルの抗異化作用が卵巣摘出マウスの骨量減少に及ぼす影響：マイクロコンピュータ断層撮影法による研究と組織学的解析

Anti-catabolic effect of caffeic acid phenethyl ester, an active component of honeybee propolis on bone loss in ovariectomized mice: a micro-computed tomography study and histological analysis.
  • Wangping Duan
  • Qing Wang
  • Fang Li
  • Chuan Xiang
  • Lin Zhou
  • Jiake Xu
  • Haotian Feng
  • Xiaochun Wei
  • Chin. Med. J..2014;127(22):3932-6.

レジストリデータへの機械学習の応用。小児頭蓋顔面周術期登録データセットを用いた頭蓋顔面手術中の輸血必要量の患者別予測モデルの開発

Machine Learning Applied to Registry Data: Development of a Patient-Specific Prediction Model for Blood Transfusion Requirements During Craniofacial Surgery Using the Pediatric Craniofacial Perioperative Registry Dataset.
  • Ali Jalali
  • Hannah Lonsdale
  • Lillian V Zamora
  • Luis Ahumada
  • Anh Thy H Nguyen
  • Mohamed Rehman
  • James Fackler
  • Paul A Stricker
  • Allison M Fernandez
  • Anesth. Analg..2020 06;doi: 10.1213/ANE.0000000000004988.Epub 2020-06-30.

PD-1遮断薬に対する遺伝的抵抗性メカニズムの克服

Overcoming genetically-based resistance mechanisms to PD-1 blockade.
  • Davis Y Torrejon
  • Gabriel Abril-Rodriguez
  • Ameya S Champhekar
  • Jennifer Tsoi
  • Katie M Campbell
  • Anusha Kalbasi
  • Giulia Parisi
  • Jesse M Zaretsky
  • Angel Garcia-Diaz
  • Cristina Puig-Saus
  • Gardenia Cheung-Lau
  • Thomas Wohlwender
  • Paige Krystofinski
  • Agustin Vega-Crespo
  • Christopher M Lee
  • Pau Mascaro
  • Catherine S Grasso
  • Beata Berent-Maoz
  • Begona Comin-Anduix
  • Siwen Hu-Lieskovan
  • Antoni Ribas
  • Cancer Discov.2020 May;CD-19-1409. doi: 10.1158/2159-8290.CD-19-1409.Epub 2020-05-28.

ボルテゾミブ維持療法を標準治療として行うことで、骨髄腫と診断されたばかりの患者さんに良好な結果が得られます。多施設での実際の研究

Bortezomib Maintenance Therapy as a Standard of Care Provides Favorable Outcomes in Newly Diagnosed Myeloma Patients: A Multisite Real-Life Study.
  • Efrat Luttwak
  • Moshe E Gatt
  • Eyal Lebel
  • Noa Lavi
  • Tamar Tadmor
  • Kreiniz Natalia
  • Noam Benyamini
  • Netanel Horowitz
  • Mika Geva
  • Celia Suriu
  • Irit Avivi
  • Svetlana Trestman
  • Moshe Mittelman
  • Ory Rouvio
  • Yael C Cohen
  • Clin Lymphoma Myeloma Leuk.2020 Jun;S2152-2650(20)30285-8. doi: 10.1016/j.clml.2020.06.002.Epub 2020-06-11.

ナトリウム-水素交換体-1（NHE-1）の阻害剤であるアミロリドは、虚血後の亜鉛蓄積を減少させ、海馬の神経細胞死を抑制した

An Inhibitor of the Sodium-Hydrogen Exchanger-1 (NHE-1), Amiloride, Reduced Zinc Accumulation and Hippocampal Neuronal Death after Ischemia.
  • Beom Seok Kang
  • Bo Young Choi
  • A Ra Kho
  • Song Hee Lee
  • Dae Ki Hong
  • Jeong Hyun Jeong
  • Dong Hyeon Kang
  • Min Kyu Park
  • Sang Won Suh
  • Int J Mol Sci.2020 Jun;21(12). E4232. doi: 10.3390/ijms21124232.Epub 2020-06-14.

規則（EC）No1829/2003（出願EFSA-GMO-NL-2016-135）に基づく、食品および飼料用途のための遺伝子組換え大豆MON 87708×MON 89788×A5547-127の評価

Assessment of genetically modified soybean MON 87708 × MON 89788 × A5547-127, for food and feed uses, under Regulation (EC) No 1829/2003 (application EFSA-GMO-NL-2016-135).
  • Hanspeter Naegeli
  • Jean-Louis Bresson
  • Tamas Dalmay
  • Ian Crawford Dewhurst
  • Michele Epstein
  • Leslie George Firbank
  • Philippe Guerche
  • Jan Hejatko
  • Francisco Javier Moreno
  • Ewen Mullins
  • Fabien Nogué
  • Nils Rostoks
  • Jose Juan Sánchez Serrano
  • Giovanni Savoini
  • Eve Veromann
  • Fabio Veronesi
  • Fernando Álvarez
  • Antonio Fernandez Dumont
  • Nikoletta Papadopoulou
  • Michele Ardizzone
  • Yann Devos
  • Andrea Gennaro
  • Jose Ángel Ruiz Gómez
  • Anna Lanzoni
  • Franco Maria Neri
  • Konstantinos Paraskevopoulos
  • Tommaso Raffaello
  • Giacomo De Sanctis
  • EFSA J.2019 Jul;17(7):e05733. EFS25733. doi: 10.2903/j.efsa.2019.5733.Epub 2019-07-05.

IL-1R（インターロイキン-1受容体）シグナル伝達と肝CYP（シトクロムP450）2C発現の減衰。糖尿病患者におけるクロピドグレル抵抗性の高率の説明？

IL-1R (Interleukin-1 Receptor) Signaling and Attenuated Hepatic CYP (Cytochrome P450) 2C Expression: Explanation for Higher Rate of Clopidogrel Resistance in Patients With Diabetes Mellitus?
  • Rolf P Kreutz
  • Arterioscler. Thromb. Vasc. Biol..2020 06;40(6):1429-1431. doi: 10.1161/ATVBAHA.120.314446.Epub 2020-05-27.

ペントースリン酸経路依存性とジスルフィドストレスのシスティントランスポーター制御は、がんにおける標的となる代謝脆弱性を明らかにしている

Cystine transporter regulation of pentose phosphate pathway dependency and disulfide stress exposes a targetable metabolic vulnerability in cancer.
  • Xiaoguang Liu
  • Kellen Olszewski
  • Yilei Zhang
  • Esther W Lim
  • Jiejun Shi
  • Xiaoshan Zhang
  • Jie Zhang
  • Hyemin Lee
  • Pranavi Koppula
  • Guang Lei
  • Li Zhuang
  • M James You
  • Bingliang Fang
  • Wei Li
  • Christian M Metallo
  • Masha V Poyurovsky
  • Boyi Gan
  • Nat. Cell Biol..2020 04;22(4):476-486. 10.1038/s41556-020-0496-x. doi: 10.1038/s41556-020-0496-x.Epub 2020-03-30.

抜歯部位への同種骨髄間葉系幹細胞移植は、ゾレドロン酸治療ラットにおける顎骨壊死性骨病変の発生率を改善した

Allogeneic Bone Marrow Mesenchymal Stem Cell Transplantation in Tooth Extractions Sites Ameliorates the Incidence of Osteonecrotic Jaw-Like Lesions in Zoledronic Acid-Treated Rats.
  • Francisco Javier Rodríguez-Lozano
  • Ricardo Oñate-Sánchez
  • Mar Gonzálvez-García
  • Marta Vallés-Bergadá
  • Carlos M Martínez
  • Beatriz Revilla-Nuin
  • Julia Guerrero-Gironés
  • Jose M Moraleda
  • David García-Bernal
  • J Clin Med.2020 May;9(6). E1649. doi: 10.3390/jcm9061649.Epub 2020-05-31.

SLC35A2-CDGにおけるガラクトース補充による臨床的および生化学的改善

Clinical and biochemical improvement with galactose supplementation in SLC35A2-CDG.
  • Peter Witters
  • Shawn Tahata
  • Rita Barone
  • Katrin Õunap
  • Ramona Salvarinova
  • Sabine Grønborg
  • George Hoganson
  • Fernando Scaglia
  • Andrea Margaret Lewis
  • Mari Mori
  • Jolanta Sykut-Cegielska
  • Andrew Edmondson
  • Miao He
  • Eva Morava
  • Genet. Med..2020 Jun;22(6):1102-1107. 10.1038/s41436-020-0767-8. doi: 10.1038/s41436-020-0767-8.Epub 2020-02-27.

縦断的サイトカインプロファイリングにより、本態性血小板血症における疾患進行の潜在的バイオマーカーとしてGRO-αとEGFが同定された

Longitudinal Cytokine Profiling Identifies GRO-α and EGF as Potential Biomarkers of Disease Progression in Essential Thrombocythemia.
  • Nina F Øbro
  • Jacob Grinfeld
  • Miriam Belmonte
  • Melissa Irvine
  • Mairi S Shepherd
  • Tata Nageswara Rao
  • Axel Karow
  • Lisa M Riedel
  • Oliva B Harris
  • E Joanna Baxter
  • Jyoti Nangalia
  • Anna Godfrey
  • Claire N Harrison
  • Juan Li
  • Radek C Skoda
  • Peter J Campbell
  • Anthony R Green
  • David G Kent
  • Hemasphere.2020 Jun;4(3):e371. HemaSphere-2020-0041. doi: 10.1097/HS9.0000000000000371.Epub 2020-05-21.

HIV のウイルス学的に抑制された成人におけるビクトグラビル、エムトリシタビン、テノフォビル・アラフェナミドへの切り替え

Switching to bictegravir, emtricitabine, and tenofovir alafenamide in virologically suppressed adults with HIV.
  • Paul E Sax
  • Jürgen K Rockstroh
  • Anne F Luetkemeyer
  • Yazdan Yazdanpanah
  • Douglas Ward
  • Benoit Trottier
  • Armin Rieger
  • Hui Liu
  • Rima Acosta
  • Sean E Collins
  • Diana M Brainard
  • Hal Martin
  • Clin. Infect. Dis..2020 Jul;ciaa988. doi: 10.1093/cid/ciaa988.Epub 2020-07-15.

インフルエンザパンデミックまたはその他の公衆衛生上の災害における人工呼吸器の割り当てにおける臨床的および倫理的配慮。2007年と2015年のニューヨーク州人工呼吸器割当ガイドラインの比較

Clinical and Ethical Considerations in Allocation of Ventilators in an Influenza Pandemic or Other Public Health Disaster: A Comparison of the 2007 and 2015 New York State Ventilator Allocation Guidelines.
  • Susie A Han
  • Valerie Gutmann Koch
  • Disaster Med Public Health Prep.2020 Jul;:1-27. S1935789320002323. doi: 10.1017/dmp.2020.232.Epub 2020-07-14.

南アフリカにおける規制の枠組みのテスト - 細菌性膣症の女性における標準治療に対する市販のプロバイオティクスサプリメントの単盲検無作為化パイロット試験

Testing the regulatory framework in South Africa - a single-blind randomized pilot trial of commercial probiotic supplementation to standard therapy in women with bacterial vaginosis.
  • Anna-Ursula Happel
  • Ravesh Singh
  • Nireshni Mitchev
  • Koleka Mlisana
  • Heather B Jaspan
  • Shaun L Barnabas
  • Jo-Ann S Passmore
  • BMC Infect. Dis..2020 Jul;20(1):491. 10.1186/s12879-020-05210-4. doi: 10.1186/s12879-020-05210-4.Epub 2020-07-10.

生理活性ペプチドはオートファジーとミトコンドリアの生合成経路を活性化することで、高血圧自然発症ラット心臓のアポトーシスを抑制します

Bioactive peptides attenuate cardiac apoptosis in spontaneously hypertensive rat hearts through activation of autophagy and mitochondrial biogenesis pathway.
  • Wan Teng Lin
  • Srinivasan Nithiyanantham
  • Dennis Jine-Yuan Hsieh
  • Ray-Jade Chen
  • Cecilia-Hsuan Day
  • Jia Ying Liao
  • Chia-Hua Kuo
  • B Mahalakshmi
  • Wei-Wen Kuo
  • Chih-Yang Huang
  • Environ. Toxicol..2020 Jul;35(7):804-810. doi: 10.1002/tox.22916.Epub 2020-03-05.

日常生活能力に制限のある在宅で生活し、在宅介護を受ける高齢者を対象としたインテリジェントな在宅緊急通報システムのセキュリティと利用者受け入れ

[Security and user acceptance of an intelligent home emergency call system for older people living at home with limited daily living skills and receiving home care].
  • Albert Lukas
  • Irene Maucher
  • Sandra Bugler
  • Daniel Flemming
  • Ingo Meyer
  • Z Gerontol Geriatr.2020 Jul;10.1007/s00391-020-01763-w. doi: 10.1007/s00391-020-01763-w.Epub 2020-07-17.

原発性骨髄線維症骨髄由来CD14+/CD34-単球は免疫不全マウスに骨髄線維症様の表現型を誘導し、巨核球を産生する

Primary myelofibrosis marrow-derived CD14+/CD34- monocytes induce myelofibrosis-like phenotype in immunodeficient mice and give rise to megakaryocytes.
  • Taghi Manshouri
  • Srdan Verstovsek
  • David M Harris
  • Ivo Veletic
  • Xiaorui Zhang
  • Sean M Post
  • Carlos E Bueso-Ramos
  • Zeev Estrov
  • PLoS ONE.2019;14(9):e0222912. PONE-D-19-02820. doi: 10.1371/journal.pone.0222912.Epub 2019-09-30.

クロロフェノールのヒトチトクロームP450 3A4に対する阻害作用の評価と各種種間の違いについて

Evaluation of the inhibition of chlorophenols towards human cytochrome P450 3A4 and differences among various species.
  • Nai-Rong Liu
  • Kai Yang
  • Wen-Ting Li
  • Zhi-Hua Pang
  • Qing Zhang
  • Jia-Jia Wang
  • Wen-Xi Dang
  • Ruo-Yong Jia
  • Zhi-Wei Fu
  • Yi-Xuan Li
  • Zhu-Hua Yao
  • Zhong-Ze Fang
  • Sci. Total Environ..2020 Jul;724:138187. S0048-9697(20)31700-9. doi: 10.1016/j.scitotenv.2020.138187.Epub 2020-03-28.

初回エピソード精神病のクライエントにおけるケースマネジメント・クオリティ・オブ・ケア尺度（CMQS）の開発、信頼性、妥当性

Development, reliability and validity of the case management quality of care scale (CMQS) among clients with first episode psychosis.
  • Horng Hien Wong
  • Edimansyah Abdin
  • Janhavi Vaingankar
  • Yi Chian Chua
  • Yee Huei Yong
  • Shazana Shahwan
  • Laxman Cetty
  • Charlene Hon
  • Wei Quan Jeremy Chan
  • Helen Lee
  • Swapna Verma
  • Mythily Subramaniam
  • Asian J Psychiatr.2020 Jul;54:102271. S1876-2018(20)30383-X. doi: 10.1016/j.ajp.2020.102271.Epub 2020-07-11.

深部浸潤性子宮内膜症に対する大腸肛門分割切除術（ENDO-RESECT morb）後の手術関連合併症と長期的な機能的罹患率

Surgery-related complications and long-term functional morbidity after segmental colo-rectal resection for deep infiltrating endometriosis (ENDO-RESECT morb).
  • Luigi Carlo Turco
  • Lucia Tortorella
  • Attilio Tuscano
  • Marco Antonio Palumbo
  • Anna Fagotti
  • Stefano Uccella
  • Francesco Fanfani
  • Gabriella Ferrandina
  • Nicola Nicolotti
  • Virginia Vargiu
  • Claudio Lodoli
  • Franco Scaldaferri
  • Giovanni Scambia
  • Francesco Cosentino
  • Arch. Gynecol. Obstet..2020 Jul;10.1007/s00404-020-05694-0. doi: 10.1007/s00404-020-05694-0.Epub 2020-07-16.

スーダンの生殖年齢女性における貧血の有病率と決定因子：家計調査の横断的分析

Prevalence and determinants of anaemia in women of reproductive age in Sudan: analysis of a cross-sectional household survey.
  • Khalid Abdelmutalab Elmardi
  • Ishag Adam
  • Elfatih Mohammed Malik
  • Tarig Abdalla Abdelrahim
  • Mousab Siddig Elhag
  • Abdalla Ahmed Ibrahim
  • Mariam Adam Babiker
  • Asma Hashim Elhassan
  • Hmooda Toto Kafy
  • Azza Tageldin Elshafie
  • Lubna Mohammed Nawai
  • Mujahid Sheikhedin Abdin
  • Stef Kremers
  • BMC Public Health.2020 Jul;20(1):1125. 10.1186/s12889-020-09252-w. doi: 10.1186/s12889-020-09252-w.Epub 2020-07-17.

リースケ鉄硫黄タンパク質はNF-κB/サイクリンD1経路を介してFKBP12.6/RyR2複合体のリモデリングとその後の肺高血圧を誘導する

Rieske iron-sulfur protein induces FKBP12.6/RyR2 complex remodeling and subsequent pulmonary hypertension through NF-κB/cyclin D1 pathway.
  • Lin Mei
  • Yun-Min Zheng
  • Tengyao Song
  • Vishal R Yadav
  • Leroy C Joseph
  • Lillian Truong
  • Sharath Kandhi
  • Margarida M Barroso
  • Hiroshi Takeshima
  • Marc A Judson
  • Yong-Xiao Wang
  • Nat Commun.2020 Jul;11(1):3527. 10.1038/s41467-020-17314-1. doi: 10.1038/s41467-020-17314-1.Epub 2020-07-15.

実験的に誘発されたマウスの筋骨格系疼痛の行動・生化学的障害における酸化ストレスと神経成長因子の関与：ヘラクリンの改善効果

Involvement of Oxidative Stress and Nerve Growth Factor in Behavioral and Biochemical Deficits of Experimentally Induced Musculoskeletal Pain in Mice: Ameliorative Effects of Heraclin.
  • Anudeep Kaur
  • Lovedeep Singh
  • Saweta Garg
  • Harmanpreet Kaur
  • Nirmal Singh
  • Rajbir Bhatti
  • J. Mol. Neurosci..2020 Jul;10.1007/s12031-020-01656-y. doi: 10.1007/s12031-020-01656-y.Epub 2020-07-16.

訂正しました。局所細分化糸球体硬化症げっ歯類モデルにおける腎障害に対する保護のためのリポジトリコルチコトロピン注射対コルチコステロイド

Correction to: Repository corticotropin injection versus corticosteroids for protection against renal damage in a focal segmental glomerulosclerosis rodent model.
  • Kyle Hayes
  • Elizabeth Warner
  • Chris Bollinger
  • Dale Wright
  • Richard M Fitch
  • BMC Nephrol.2020 Jul;21(1):278. 10.1186/s12882-020-01933-3. doi: 10.1186/s12882-020-01933-3.Epub 2020-07-16.

冠動脈バイパスグラフト治療中にスタチン系コレステロール低下薬を服用しているタイ人患者における高脂血症および冠動脈性心疾患におけるインターロイキン-8の検討

Interleukin-8 in Hyperlipidemia and Coronary Heart Disease in Thai Patients Taking Statin Cholesterol-Lowering Medication While Undergoing Coronary Artery Bypass Grafting Treatment.
  • Wilanee Dechkhajorn
  • Yaowapa Maneerat
  • Kriengchai Prasongsukarn
  • Panan Kanchanaphum
  • Ratchanok Kumsiri
  • Scientifica (Cairo).2020;2020:5843958. doi: 10.1155/2020/5843958.Epub 2020-06-17.

健康マウスおよびストレプトゾトシン誘発糖尿病マウスにおける坐骨神経ブロック後のブピバカインおよびリポソームブピバカインの神経毒性

Neurotoxicity of bupivacaine and liposome bupivacaine after sciatic nerve block in healthy and streptozotocin-induced diabetic mice.
  • Liljana Markova
  • Nejc Umek
  • Simon Horvat
  • Admir Hadžić
  • Max Kuroda
  • Tatjana Stopar Pintarič
  • Vesna Mrak
  • Erika Cvetko
  • BMC Vet. Res..2020 Jul;16(1):247. 10.1186/s12917-020-02459-4. doi: 10.1186/s12917-020-02459-4.Epub 2020-07-17.

イソオリエンチンは、活性酸素制御MAPK、STAT3、NF-κBシグナル伝達経路を介して、A549ヒト肺癌細胞のアポトーシスと細胞周期停止を誘導します

Isoorientin induces the apoptosis and cell cycle arrest of A549 human lung cancer cells via the ROS‑regulated MAPK, STAT3 and NF‑κB signaling pathways.
  • Wan-Ting Xu
  • Gui-Nan Shen
  • Tian-Zhu Li
  • Yu Zhang
  • Tong Zhang
  • Hui Xue
  • Wen-Bo Zuo
  • Yan-Nan Li
  • Dong-Jie Zhang
  • Cheng-Hao Jin
  • Int. J. Oncol..2020 Aug;57(2):550-561. doi: 10.3892/ijo.2020.5079.Epub 2020-06-09.

蘭科胡蝶蘭の原虫発生過程におけるグリオキシル酸サイクルに関与するMALATE SYNTHASEの発現制御

Expression regulation of MALATE SYNTHASE involved in glyoxylate cycle during protocorm development in Phalaenopsis aphrodite (Orchidaceae).
  • Wan-Lin Wu
  • Yu-Yun Hsiao
  • Hsiang-Chia Lu
  • Chieh-Kai Liang
  • Chih-Hsiung Fu
  • Tian-Hsiang Huang
  • Ming-Hsiang Chuang
  • Li-Jun Chen
  • Zhong-Jian Liu
  • Wen-Chieh Tsai
  • Sci Rep.2020 Jun;10(1):10123. 10.1038/s41598-020-66932-8. doi: 10.1038/s41598-020-66932-8.Epub 2020-06-22.

抽出および増幅ステップからのタクソンの出現は、マダニマイクロバイオータ解析におけるマルチプルコントロールの価値を実証しています

Taxon Appearance From Extraction and Amplification Steps Demonstrates the Value of Multiple Controls in Tick Microbiota Analysis.
  • Emilie Lejal
  • Agustín Estrada-Peña
  • Maud Marsot
  • Jean-François Cosson
  • Olivier Rué
  • Mahendra Mariadassou
  • Cédric Midoux
  • Muriel Vayssier-Taussat
  • Thomas Pollet
  • Front Microbiol.2020;11:1093. doi: 10.3389/fmicb.2020.01093.Epub 2020-06-09.

ナトリウム-グルコースコトランスポーター2阻害薬であるカナグリフロジンは、糖尿病ラットにおける腎酸化ストレスの低減を介して1型心筋症候群に対する腎感受性を正常化する

Canagliflozin, a sodium-glucose cotransporter 2 inhibitor, normalizes renal susceptibility to type 1 cardiorenal syndrome through reduction of renal oxidative stress in diabetic rats.
  • Yukishige Kimura
  • Atsushi Kuno
  • Masaya Tanno
  • Tatsuya Sato
  • Kouhei Ohno
  • Satoru Shibata
  • Kei Nakata
  • Hirohito Sugawara
  • Koki Abe
  • Yusuke Igaki
  • Toshiyuki Yano
  • Takayuki Miki
  • Tetsuji Miura
  • J Diabetes Investig.2019 Jul;10(4):933-946. doi: 10.1111/jdi.13009.Epub 2019-02-25.

ヒト血漿および尿中のカナグリフロジン、ダパグリフロジン、エンパグリフロジンを同時に定量するためのシンプルで高速かつ堅牢なLC-MS/MS法

Simple, fast and robust LC-MS/MS method for the simultaneous quantification of canagliflozin, dapagliflozin and empagliflozin in human plasma and urine.
  • Annemarie B van der Aart-van der Beek
  • A Mireille A Wessels
  • Hiddo J L Heerspink
  • Daan J Touw
  • J. Chromatogr. B Analyt. Technol. Biomed. Life Sci..2020 Jun;1152:122257. S1570-0232(20)30276-2. doi: 10.1016/j.jchromb.2020.122257.Epub 2020-06-26.

ブプレノルフィン/ナロキソンを服用している成人の支援者を対象としたグループベースの治療法を評価するための研究デザイン

Study design to evaluate a group-based therapy for support persons of adults on buprenorphine/naloxone.
  • Karen Chan Osilla
  • Kirsten Becker
  • Liisa Ecola
  • Brian Hurley
  • Jennifer K Manuel
  • Allison Ober
  • Susan M Paddock
  • Katherine E Watkins
  • Addict Sci Clin Pract.2020 Jul;15(1):25. 10.1186/s13722-020-00199-2. doi: 10.1186/s13722-020-00199-2.Epub 2020-07-11.

COVID-19感染に関連する危険因子：接触者追跡に基づくレトロスペクティブコホート研究

Risk factors associated with COVID-19 infection: a retrospective cohort study based on contacts tracing.
  • Tao Liu
  • Wenjia Liang
  • Haojie Zhong
  • Jianfeng He
  • Zihui Chen
  • Guanhao He
  • Tie Song
  • Shaowei Chen
  • Ping Wang
  • Jialing Li
  • Yunhua Lan
  • Mingji Cheng
  • Jinxu Huang
  • Jiwei Niu
  • Liang Xia
  • Jianpeng Xiao
  • Jianxiong Hu
  • Lifeng Lin
  • Qiong Huang
  • Zuhua Rong
  • Aiping Deng
  • Weilin Zeng
  • Jiansen Li
  • Xing Li
  • Xiaohua Tan
  • Min Kang
  • Lingchuan Guo
  • Zhihua Zhu
  • Dexin Gong
  • Guimin Chen
  • Moran Dong
  • Wenjun Ma
  • Emerg Microbes Infect.2020 Dec;9(1):1546-1553. doi: 10.1080/22221751.2020.1787799.

角膜形成術後の緑内障におけるオーラブ水性ドレナージインプラントとアーメド緑内障バルブの短期成績の比較。第三次医療センターでのレトロスペクティブフォローアップ研究

Comparison of Short-term Outcomes of Aurolab Aqueous Drainage Implant with Ahmed Glaucoma Valve in Post-Penetrating Keratoplasty Glaucoma: A Retrospective Follow-up Study at a Tertiary Care Center.
  • Srishti Raj
  • Ajay Jurangal
  • Gaurav Gupta
  • Faisal Thattaruthody
  • Natasha Gautam Seth
  • Surinder Singh Pandav
  • Ophthalmol Glaucoma.2019 May - Jun;2(3):172-177. S2589-4196(18)30194-7. doi: 10.1016/j.ogla.2019.02.005.Epub 2019-02-12.