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日本語AIでPubMedを検索

歯科医師情報サイトTOP / PubMed論文検索

日本語AIでPubMedを検索

PubMedの提供する医学論文データベースを日本語で検索できます。AI(Deep Learning)を活用した機械翻訳エンジンにより、精度高く日本語へ翻訳された論文をご参照いただけます。
対象期間    ～ 

2020年07月 みんなが読んでいる論文

自分のチームを知る。緊急時における効果的な水平的ケアデリバリーのための研修医・フェローの迅速な評価

Knowing Your Team: Rapid Assessment of Residents and Fellows for Effective Horizontal Care Delivery in Emergency Events.
  • Bradley Dennis
  • Alexandra Highet
  • Daniel Kendrick
  • Laura Mazer
  • Sean Loiselle
  • Hoda Bandeh-Ahmadi
  • Tanvi Gupta
  • Kenneth Abbott
  • Jarrett Lea
  • Thu Dang
  • Mischon Ramey
  • Brian George
  • Kyla Terhune
  • J Grad Med Educ.2020 Jun;12(3):272-279. doi: 10.4300/JGME-D-20-00290.1.

初期環境と遺伝的素因の相互作用は、子供の代謝的肥満、正常体重の表現型を誘発する：BCAMS研究から得られた知見

Interaction between early environment and genetic predisposition instigates the metabolically obese, normal weight phenotype in children: findings from the BCAMS study.
  • Ge Li
  • Yu Li
  • Lanwen Han
  • Dongmei Wang
  • Qian Zhang
  • Xinhua Xiao
  • Lu Qi
  • Steven M Willi
  • Ming Li
  • Jie Mi
  • Shan Gao
  • Eur. J. Endocrinol..2020 Apr;182(4):393-403. EJE-19-0755. doi: 10.1530/EJE-19-0755.

ガンマオリザノールは、BdnfおよびIl-1βシグナル伝達に関連する中枢性モノアミンのアップレギュレーションを介して、マウスのアルコール誘発性不安様行動を損なう

Gamma oryzanol impairs alcohol-induced anxiety-like behavior in mice via upregulation of central monoamines associated with Bdnf and Il-1β signaling.
  • Salina Akter
  • Kazi Rasel Uddin
  • Hiroyuki Sasaki
  • Yijin Lyu
  • Shigenobu Shibata
  • Sci Rep.2020 Jun;10(1):10677. 10.1038/s41598-020-67689-w. doi: 10.1038/s41598-020-67689-w.Epub 2020-06-30.

老化した BALB/cByJ マウスにおける皮膚創傷治癒老化の定量化と線維芽細胞成長因子-1 による治療介入の可能性

Fine-Sampled Photographic Quantitation of Dermal Wound Healing Senescence in Aged BALB/cByJ Mice and Therapeutic Intervention with Fibroblast Growth Factor-1.
  • Alana P Mellers
  • Connie A Tenorio
  • Diana A Lacatusu
  • Brett D Powell
  • Bhavi N Patel
  • Kathleen M Harper
  • Michael Blaber
  • Adv Wound Care (New Rochelle).2018 Dec;7(12):409-418. 10.1089/wound.2018.0801. doi: 10.1089/wound.2018.0801.Epub 2018-12-08.

眼窩底骨折に対する外科的アプローチ。眼窩底骨折に対する外科的アプローチ：毛様体下アプローチと結膜下アプローチの合併症率の比較

Surgical Approach to Orbital Floor Fractures: Comparing Complication Rates Between Subciliary and Subconjunctival Approaches.
  • Joel A Bronstein
  • William J Bruce
  • Fadi Bakhos
  • Dalia Ishaq
  • Cara J Joyce
  • Victor Cimino
  • Craniomaxillofac Trauma Reconstr.2020 Mar;13(1):45-48. 10.1177_1943387520904893. doi: 10.1177/1943387520904893.Epub 2020-03-16.

膵β細胞におけるルビコンは、インスリン抵抗性の増加に伴うグルコースホメオスタシスの維持に限られた役割を果たしている

Rubicon in pancreatic beta cells plays a limited role in maintaining glucose homeostasis following increased insulin resistance.
  • Shuhei Aoyama
  • Yuya Nishida
  • Yoshio Fujitani
  • Ayako Fukunaka
  • Takeshi Miyatsuka
  • Luka Suzuki
  • Miwa Himuro
  • Tamotsu Yoshimori
  • Hirotaka Watada
  • Endocr. J..2020 Jul;doi: 10.1507/endocrj.EJ20-0326.Epub 2020-07-16.

ヒトおよび動物由来のプロテウス・ミラビリスの単一系統：EnterobacteralesにおけるOXA-23またはOXA-58カルバペネマーゼの隠れた貯蔵庫

A single Proteus mirabilis lineage from human and animal sources: a hidden reservoir of OXA-23 or OXA-58 carbapenemases in Enterobacterales.
  • Rémy A Bonnin
  • Delphine Girlich
  • Agnès B Jousset
  • Lauraine Gauthier
  • Gaëlle Cuzon
  • Pierre Bogaerts
  • Marisa Haenni
  • Jean-Yves Madec
  • Elodie Couvé-Deacon
  • Olivier Barraud
  • Nicolas Fortineau
  • Philippe Glaser
  • Youri Glupczynski
  • Laurent Dortet
  • Thierry Naas
  • Sci Rep.2020 Jun;10(1):9160. 10.1038/s41598-020-66161-z. doi: 10.1038/s41598-020-66161-z.Epub 2020-06-08.

イヌと毛皮動物の感染症から分離されたStreptococcus halichoeriの比較：生化学的パターン、分子特性、遺伝的関連性

Comparison of Streptococcus halichoeri isolates from canine and fur animal infections: biochemical patterns, molecular characteristics and genetic relatedness.
  • Marjut Eklund
  • Kirsi Aaltonen
  • Tarja Sironen
  • Mirja Raunio-Saarnisto
  • Thomas Grönthal
  • Heli Nordgren
  • Anna Pitkälä
  • Olli Vapalahti
  • Merja Rantala
  • Acta Vet. Scand..2020 Jun;62(1):26. 10.1186/s13028-020-00525-3. doi: 10.1186/s13028-020-00525-3.Epub 2020-06-03.

中年男性におけるアルコール摂取量およびアポリポ蛋白質E（ApoE）遺伝子型と認知との相互作用

Interaction between Alcohol Consumption and Apolipoprotein E (ApoE) Genotype with Cognition in Middle-Aged Men.
  • Riki E Slayday
  • Daniel E Gustavson
  • Jeremy A Elman
  • Asad Beck
  • Linda K McEvoy
  • Xin M Tu
  • Bin Fang
  • Richard L Hauger
  • Michael J Lyons
  • Ruth E McKenzie
  • Mark E Sanderson-Cimino
  • Hong Xian
  • William S Kremen
  • Carol E Franz
  • J Int Neuropsychol Soc.2020 Jul;:1-13. S1355617720000570. doi: 10.1017/S1355617720000570.Epub 2020-07-14.

濾胞性リンパ腫と閉塞性気管支炎を合併した抗デスモグレイン3、抗デスモコリン2、3自己抗体を有する天疱瘡の1例

A case of pemphigus with anti-desmoglein 3 and anti-desmocollin 2 and 3 autoantibodies, associated with follicular lymphoma and bronchiolitis obliterans.
  • Masato Yoshikawa
  • Takuya Takeichi
  • Tomoki Taki
  • Fumihiko Hayakawa
  • Norito Ishii
  • Takashi Hashimoto
  • Yoshinao Muro
  • Masashi Akiyama
  • Eur J Dermatol.2020 Jul;ejd.2020.3812. doi: 10.1684/ejd.2020.3812.Epub 2020-07-09.

比較的高いエネルギー密度を持つエネルギー貯蔵EDLCデバイスアプリケーションのためのグリセリン化リチウムイオン伝導キトサンベースのポリマー電解質

Glycerolized Li Ion Conducting Chitosan-Based Polymer Electrolyte for Energy Storage EDLC Device Applications with Relatively High Energy Density.
  • Ahmed S F M Asnawi
  • Shujahadeen B Aziz
  • Muaffaq M Nofal
  • Muhamad H Hamsan
  • Mohamad A Brza
  • Yuhanees M Yusof
  • Rebar T Abdilwahid
  • Saifful K Muzakir
  • Mohd F Z Kadir
  • Polymers (Basel).2020 Jun;12(6). E1433. doi: 10.3390/polym12061433.Epub 2020-06-26.

カスタムのPatient-Reported Outcomes Measurement Information System (PROMIS)身体機能短縮形および腱鞘巨大細胞腫瘍における最悪の硬直度数値評価スケールの心理測定特性

Psychometric properties of a custom Patient-Reported Outcomes Measurement Information System (PROMIS) physical function short form and worst stiffness numeric rating scale in tenosynovial giant cell tumors.
  • Rebecca M Speck
  • Xin Ye
  • Nicholas M Bernthal
  • Heather L Gelhorn
  • J Patient Rep Outcomes.2020 Jul;4(1):61. 10.1186/s41687-020-00217-6. doi: 10.1186/s41687-020-00217-6.Epub 2020-07-16.

腫瘍関連炭酸脱水酵素アイソフォームIXおよびXIIに対するウンベリフェロンベースの化合物の合成、計算研究および阻害活性の評価

Synthesis, computational studies and assessment of inhibitory activity of umbelliferon-based compounds against tumour-associated carbonic anhydrase isoforms IX and XII.
  • Francesca Mancuso
  • Laura De Luca
  • Andrea Angeli
  • Sonia Del Prete
  • Clemente Capasso
  • Claudiu T Supuran
  • Rosaria Gitto
  • J Enzyme Inhib Med Chem.2020 Dec;35(1):1442-1449. doi: 10.1080/14756366.2020.1786821.

バルブインバルブトランスカテーテル大動脈弁置換術中の生体補綴弁骨折

Bioprosthetic valve fracture during valve-in-valve transcatheter aortic valve replacement.
  • Mohanad Hamandi
  • Ikenna Nwafor
  • Katherine R Hebeler
  • Alexander Crawford
  • Allison T Lanfear
  • Justin Schaffer
  • Karim Al-Azizi
  • Srinivasa Potluri
  • William T Brinkman
  • Katherine Harrington
  • Molly Szerlip
  • J Michael DiMaio
  • Proc (Bayl Univ Med Cent).2020 Jul;33(3):317-321. 1732267. doi: 10.1080/08998280.2020.1732267.Epub 2020-03-06.

健常者および睡眠時無呼吸症候群患者の閉塞性イベント時にマルチディテクターCTで評価した上気道の状態依存性変化

State-dependent changes in the upper airway assessed by multidetector CT in healthy individuals and during obstructive events in patients with sleep apnea.
  • Ula Lindoso Passos
  • Pedro Rodrigues Genta
  • Bianca Fernandes Marcondes
  • Geraldo Lorenzi-Filho
  • Eloisa Maria Mello Santiago Gebrim
  • J Bras Pneumol.2019 Aug;45(4):e20180264. S1806-37132019000400207. doi: 10.1590/1806-3713/e20180264.Epub 2019-08-15.

不健康な薬物使用のスクリーニング。米国予防サービスタスクフォースのための更新されたエビデンス報告書および系統的レビュー

Screening for Unhealthy Drug Use: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force.
  • Carrie D Patnode
  • Leslie A Perdue
  • Megan Rushkin
  • Tracy Dana
  • Ian Blazina
  • Christina Bougatsos
  • Sara Grusing
  • Elizabeth A O'Connor
  • Rongwei Fu
  • Roger Chou
  • JAMA.2020 06;323(22):2310-2328. 2766872. doi: 10.1001/jama.2019.21381.

大動脈弁置換術後の大動脈狭窄のフロー勾配パターンの転帰。PARTNER 2試験とレジストリの解析

Outcome of Flow-Gradient Patterns of Aortic Stenosis After Aortic Valve Replacement: An Analysis of the PARTNER 2 Trial and Registry.
  • Erwan Salaun
  • Marie-Annick Clavel
  • Rebecca T Hahn
  • Wael A Jaber
  • Federico M Asch
  • Leonardo Rodriguez
  • Neil J Weissman
  • Zachary M Gertz
  • Howard C Herrmann
  • Abdellaziz Dahou
  • Mohamed-Salah Annabi
  • Oumhani Toubal
  • Mathieu Bernier
  • Jonathan Beaudoin
  • Jonathon Leipsic
  • Philipp Blanke
  • Carine Ridard
  • Géraldine Ong
  • Josep Rodés-Cabau
  • John G Webb
  • Yiran Zhang
  • Maria C Alu
  • Pamela S Douglas
  • Raj Makkar
  • D Craig Miller
  • Brian R Lindman
  • Vinod H Thourani
  • Martin B Leon
  • Philippe Pibarot
  • Circ Cardiovasc Interv.2020 Jul;13(7):e008792. doi: 10.1161/CIRCINTERVENTIONS.119.008792.Epub 2020-07-17.

VNUT/SLC17A9は小胞性ヌクレオチドトランスポーターであり、骨芽細胞の分化を制御している

VNUT/SLC17A9, a vesicular nucleotide transporter, regulates osteoblast differentiation.
  • Asako Inoue
  • Kayoko Nakao-Kuroishi
  • Kaori Kometani-Gunjigake
  • Masahiro Mizuhara
  • Tomohiko Shirakawa
  • Misa Ito-Sago
  • Kazuma Yasuda
  • Mitsushiro Nakatomi
  • Takuma Matsubara
  • Yukiyo Tada-Shigeyama
  • Kazumasa Morikawa
  • Shoichiro Kokabu
  • Tatsuo Kawamoto
  • FEBS Open Bio.2020 Jun;doi: 10.1002/2211-5463.12918.Epub 2020-06-26.

オランザピン誘発代謝変化におけるTRPV1/TRPV3チャネルの役割。オランザピン誘発性代謝変化におけるTRPV1/TRPV3チャネルの役割：視床下部のエネルギー感知、食欲調節、炎症、中脳辺縁系経路への関与の可能性

Role of TRPV1/TRPV3 channels in olanzapine-induced metabolic alteration: Possible involvement in hypothalamic energy-sensing, appetite regulation, inflammation and mesolimbic pathway.
  • Raghunath Singh
  • Yashika Bansal
  • Rupinder Kaur Sodhi
  • Pragyanshu Khare
  • Mahendra Bishnoi
  • Kanthi Kiran Kondepudi
  • Bikash Medhi
  • Anurag Kuhad
  • Toxicol. Appl. Pharmacol..2020 Jul;402:115124. S0041-008X(20)30250-7. doi: 10.1016/j.taap.2020.115124.Epub 2020-07-09.

SRPK1のアセチル化がオルタナティブスプライシングを調節し、乳がん細胞のシスプラチン抵抗性を制御していることが明らかになった

SRPK1 acetylation modulates alternative splicing to regulate cisplatin resistance in breast cancer cells.
  • Cheng Wang
  • Zhihong Zhou
  • Charannya Sozheesvari Subhramanyam
  • Qiong Cao
  • Zealyn Shi Lin Heng
  • Wen Liu
  • Xiangdong Fu
  • Qidong Hu
  • Commun Biol.2020 May;3(1):268. 10.1038/s42003-020-0983-4. doi: 10.1038/s42003-020-0983-4.Epub 2020-05-27.

細胞診不定の甲状腺結節における7パネル突然変異検査の診断・予後評価：SWEETMAC試験

Diagnostic and prognostic value of a 7-panel mutation testing in thyroid nodules with indeterminate cytology: the SWEETMAC study.
  • Stéphane Bardet
  • Nicolas Goardon
  • Justine Lequesne
  • Dominique Vaur
  • Renaud Ciappuccini
  • Alexandra Leconte
  • Hervé Monpeyssen
  • Virginie Saguet-Rysanek
  • Bénédicte Clarisse
  • Audrey Lasne-Cardon
  • Fabrice Ménégaux
  • Laurence Leenhardt
  • Camille Buffet
  • Endocrine.2020 Jul;10.1007/s12020-020-02411-4. doi: 10.1007/s12020-020-02411-4.Epub 2020-07-07.

脂肪酸酸化は、ヒートショックプロテイン90の阻害によって前立腺腫瘍に誘導される適応的生存経路である

Fatty acid oxidation is an adaptive survival pathway induced in prostate tumors by heat shock protein 90 inhibition.
  • Zeyad D Nassar
  • Chui Yan Mah
  • Margaret M Centenera
  • Swati Irani
  • Martin C Sadowski
  • Julia S Scott
  • Elizabeth V Nguyen
  • Shilpa R Nagarajan
  • Max Moldovan
  • David J Lynn
  • Roger J Daly
  • Andrew J Hoy
  • Lisa M Butler
  • Mol. Cancer Res..2020 Jul;molcanres.0570.2020. doi: 10.1158/1541-7786.MCR-20-0570.Epub 2020-07-15.

テロメラーゼの増加は、ラットおよびヒト顆粒膜細胞およびマウス卵巣におけるステロイド原性遺伝子の発現とステロイドホルモンの産生を増強した

Increasing telomerase enhanced steroidogenic genes expression and steroid hormones production in rat and human granulosa cells and in mouse ovary.
  • Amitai Mordechai
  • Michal Wasserman
  • Marina Abramov
  • David Ben-Menahem
  • Iris Har-Vardi
  • Eliahu Levitas
  • Esther Priel
  • J. Steroid Biochem. Mol. Biol..2020 03;197:105551. S0960-0760(19)30491-1. doi: 10.1016/j.jsbmb.2019.105551.Epub 2019-11-22.

ラット肝ミクロソームにおけるCYP2C11酵素が触媒する代謝反応生成物の同時定量のためのHPLC法の検証.サリチル酸のCYP2C11酵素に対するインビトロ阻害効果（英文

Validation of an HPLC Method for the Simultaneous Quantification of Metabolic Reaction Products Catalysed by CYP2C11 Enzymes in Rat Liver Microsomes: In Vitro Inhibitory Effect of Salicylic Acid on CYP2C11 Enzyme.
  • Hassan Salhab
  • Declan P Naughton
  • James Barker
  • Molecules.2019 Nov;24(23). E4294. doi: 10.3390/molecules24234294.Epub 2019-11-25.

時空間PETイメージングにより、トリプルネガティブ乳がんモデルにおけるCAR-Tの腫瘍保持率の違いが明らかになった

Spatiotemporal PET Imaging Reveals Differences in CAR-T Tumor Retention in Triple-Negative Breast Cancer Models.
  • Alessia Volpe
  • Cameron Lang
  • Lindsay Lim
  • Francis Man
  • Ewelina Kurtys
  • Candice Ashmore-Harris
  • Preeth Johnson
  • Elena Skourti
  • Rafael T M de Rosales
  • Gilbert O Fruhwirth
  • Mol. Ther..2020 Jun;S1525-0016(20)30318-X. doi: 10.1016/j.ymthe.2020.06.028.Epub 2020-06-27.

技術ノート：教師付き機械学習を用いた腹尾基部皮膚温度の連続測定に基づく乳牛の分娩予測

Technical note: Calving prediction in dairy cattle based on continuous measurements of ventral tail base skin temperature using supervised machine learning.
  • Shogo Higaki
  • Keisuke Koyama
  • Yosuke Sasaki
  • Kodai Abe
  • Kazuyuki Honkawa
  • Yoichiro Horii
  • Tomoya Minamino
  • Yoko Mikurino
  • Hironao Okada
  • Fumikazu Miwakeichi
  • Hongyu Darhan
  • Koji Yoshioka
  • J. Dairy Sci..2020 Jul;S0022-0302(20)30494-X. doi: 10.3168/jds.2019-17689.Epub 2020-07-01.

乳糖または牛乳摂取後のラクターゼ不持続を診断するためのラクターゼ不耐症の呼気、血漿、尿中のラクターゼ吸収マーカーの評価

Evaluation of breath, plasma, and urinary markers of lactose malabsorption to diagnose lactase non-persistence following lactose or milk ingestion.
  • Aahana Shrestha
  • Matthew P G Barnett
  • Jo K Perry
  • David Cameron-Smith
  • Amber M Milan
  • BMC Gastroenterol.2020 Jun;20(1):204. 10.1186/s12876-020-01352-6. doi: 10.1186/s12876-020-01352-6.Epub 2020-06-29.

テクニカルバリアントグラフトを用いた小児肝移植における肝動脈血栓症発症率の低下．小児肝移植学会（SPLIT）の経験報告

Decreased Incidence of Hepatic Artery Thrombosis in Pediatric Liver Transplantation Utilizing Technical Variant Grafts: Report of the Society of Pediatric Liver Transplantation (SPLIT) Experience.
  • Noelle H Ebel
  • Evelyn K Hsu
  • André A S Dick
  • Michele L Shaffer
  • Kristen Carlin
  • Simon P Horslen
  • J. Pediatr..2020 Jun;S0022-3476(20)30756-3. doi: 10.1016/j.jpeds.2020.06.053.Epub 2020-06-22.

難民の再定住における健康問題。再定住した難民のためのケアの継続性を向上させるための革新的なマルチセクター・パートナーシップ

Health challenges in refugee resettlement: An innovative multi-sector partnership to improve the continuum of care for resettled refugees.
  • Erin M Mann
  • Alexander Klosovsky
  • Catherine Yen
  • Andrew P J Olson
  • Sarah J Hoffman
  • Blain Mamo
  • Ellen A Frerich
  • Michelle Weinberg
  • Harith Mayali
  • Molly McCoy
  • Shailendra Prasad
  • Stephen J Dunlop
  • William M Stauffer
  • J Travel Med.2020 Jun;taaa103. doi: 10.1093/jtm/taaa103.Epub 2020-06-24.

InGaAs/GaAs表面量子ドット対の結合構造における湿潤層とキャリアダイナミクスのフォトルミネッセンス特性を調べた

Photoluminescence characterization of wetting layer and carrier dynamics for coupled InGaAs/GaAs surface quantum dot pair structures.
  • Jingtao Liu
  • Qing Yuan
  • Baolai Liang
  • Qigeng Yan
  • Ying Wang
  • Chunsheng Wang
  • Shufang Wang
  • Guangsheng Fu
  • Yuriy I Mazur
  • Morgn E Ware
  • Gregory J Salamo
  • Opt Express.2020 Jul;28(14):20704-20713. 433041. doi: 10.1364/OE.393726.

マダガスカル南西部の風土動物および家畜の外寄生虫からRickettsia spp.、Borrelia spp.、Bartonella spp.およびYersinia pestisの分子検出

Molecular detection of Rickettsia spp., Borrelia spp., Bartonella spp. and Yersinia pestis in ectoparasites of endemic and domestic animals in southwest Madagascar.
  • Julian Ehlers
  • Andreas Krüger
  • Solofomalala Jacques Rakotondranary
  • Rakotomalala Yedidya Ratovonamana
  • Sven Poppert
  • Jörg Ulrich Ganzhorn
  • Dennis Tappe
  • Acta Trop..2020 May;205:105339. S0001-706X(19)31570-0. doi: 10.1016/j.actatropica.2020.105339.Epub 2020-01-11.

MSにおける体液性免疫応答の遺伝的決定因子

Genetic determinants of the humoral immune response in MS.
  • Christiane Gasperi
  • Till F M Andlauer
  • Ana Keating
  • Benjamin Knier
  • Ana Klein
  • Verena Pernpeintner
  • Peter Lichtner
  • Ralf Gold
  • Frauke Zipp
  • Florian Then Bergh
  • Martin Stangel
  • Hayrettin Tumani
  • Brigitte Wildemann
  • Heinz Wiendl
  • Antonios Bayas
  • Tania Kümpfel
  • Uwe K Zettl
  • Ralf A Linker
  • Ulf Ziemann
  • Matthias Knop
  • Clemens Warnke
  • Manuel A Friese
  • Friedemann Paul
  • Björn Tackenberg
  • Achim Berthele
  • Bernhard Hemmer
  • Neurol Neuroimmunol Neuroinflamm.2020 Sep;7(5). e827. doi: 10.1212/NXI.0000000000000827.Epub 2020-07-16.

三叉神経損傷の2つの代替モデルにおける身体感覚機能、痛み、不快感の評価。無作為化二重盲検対照クロスオーバー試験

Assessment of Somatosensory Function, Pain, and Unpleasantness in Two Surrogate Models of Trigeminal Nerve Damage: A Randomized, Double-Blind, Controlled Crossover Study.
  • Rajath Sasidharan Pillai
  • Maria Pigg
  • Thomas List
  • Peter Svensson
  • Lene Baad-Hansen
  • J Oral Facial Pain Headache.2020;34(2020):92–107. doi: 10.11607/ofph.2423.Epub 2019-09-27.

低酸素・神経炎症による血液脳関門機能障害を評価するための多細胞3次元神経血管ユニットモデル

Multicellular 3D Neurovascular Unit Model for Assessing Hypoxia and Neuroinflammation Induced Blood-Brain Barrier Dysfunction.
  • Goodwell Nzou
  • Robert T Wicks
  • Nicole R VanOstrand
  • Gehad A Mekky
  • Stephanie A Seale
  • Aya El-Taibany
  • Elizabeth E Wicks
  • Carl M Nechtman
  • Eric J Marotte
  • Vishruti S Makani
  • Sean V Murphy
  • M C Seeds
  • John D Jackson
  • Anthony J Atala
  • Sci Rep.2020 Jun;10(1):9766. 10.1038/s41598-020-66487-8. doi: 10.1038/s41598-020-66487-8.Epub 2020-06-17.

換気戦略が転帰および入院期間の長さに及ぼす影響：アシストコントロールと同期化間欠強制換気モード

Influence of ventilatory strategies on outcomes and length of hospital stay: assist-control and synchronized intermittent mandatory ventilation modes.
  • Thais Bruno de Godoi
  • Fernando Augusto Lima Marson
  • Camila Vantini Capasso Palamim
  • Gianna Carla Cannonieri-Nonose
  • Intern Emerg Med.2020 Jul;10.1007/s11739-020-02444-7. doi: 10.1007/s11739-020-02444-7.Epub 2020-07-17.

小児の口腔内注射前にベンゾカインゲル、クローブ-パパイヤベースの麻酔薬ゲルを外用し、注射部位のプレクーリングを行った後の痛みの知覚の比較評価

A comparative evaluation of pain perception following topical application of benzocaine gel, clove-papaya based anesthetic gel and precooling of the injection site before intraoral injections in children.
  • A Anantharaj
  • Jiline Mary Sabu
  • Sudhir Ramakrishna
  • Ramya Bangalore Jagdeesh
  • P Praveen
  • Prathibha Rani Shankarappa
  • J Indian Soc Pedod Prev Dent.2020 Apr-Jun;38(2):184-189. JIndianSocPedodPrevDent_2020_38_2_184_288216. doi: 10.4103/JISPPD.JISPPD_153_18.

(Chlorococcales)バイオマスのフェノール化合物と抗酸化能力

Phenolic compounds and antioxidant capacity of (Chlorococcales) biomass.
  • Marilia Garcez Corrêa da Silva
  • Shana Pires Ferreira
  • Cristiana Lima Dora
  • Mariana Appel Hort
  • Danilo Giroldo
  • Denise Fontoura Prates
  • Elisangela Martha Radmann
  • Renata Heidtmann Bemvenuti
  • Jorge Alberto Vieira Costa
  • Eliana Badiale-Furlong
  • Ana Luiza Muccillo-Baisch
  • Int J Environ Health Res.2020 Mar;:1-13. doi: 10.1080/09603123.2020.1744113.Epub 2020-03-23.

間葉系幹細胞由来の細胞外小胞との比較：間葉系幹細胞由来の細胞外小胞の免疫抑制作用の検討

Immunosuppressive properties of cytochalasin B-induced membrane vesicles of mesenchymal stem cells: comparing with extracellular vesicles derived from mesenchymal stem cells.
  • M O Gomzikova
  • A M Aimaletdinov
  • O V Bondar
  • I G Starostina
  • N V Gorshkova
  • O A Neustroeva
  • S K Kletukhina
  • S V Kurbangaleeva
  • V V Vorobev
  • E E Garanina
  • J L Persson
  • J Jeyapalan
  • N P Mongan
  • S F Khaiboullina
  • A A Rizvanov
  • Sci Rep.2020 Jul;10(1):10740. 10.1038/s41598-020-67563-9. doi: 10.1038/s41598-020-67563-9.Epub 2020-07-01.

唾液免疫グロブリン遊離軽鎖分析は、多発性硬化症における疾患活動と治療への反応をモニターするためのものである

Saliva immunoglobulin free light chain analysis for monitoring disease activity and response to treatment in multiple sclerosis.
  • Itay Lotan
  • Esther Ganelin-Cohen
  • Evgeny Tartakovsky
  • Vadim Khasminsky
  • Mark A Hellmann
  • Israel Steiner
  • Ilan Ben-Zvi
  • Avi Livneh
  • Sizilia Golderman
  • Batia Kaplan
  • Mult Scler Relat Disord.2020 Jun;44:102339. S2211-0348(20)30415-6. doi: 10.1016/j.msard.2020.102339.Epub 2020-06-24.

1990年から2017年までのエチオピアにおける一般的な微量栄養素欠乏の全国的な発生率、有病率、障害調整寿命年（DALYs）：世界疾病負担調査からの推定

National incidence, prevalence and disability-adjusted life years (DALYs) of common micronutrient deficiencies in Ethiopia from 1990 to 2017: estimates from the global burden of diseases study.
  • Hamid Yimam Hassen
  • Jemal Haider Ali
  • Seifu Hagos Gebreyesus
  • Bilal Shikur Endris
  • Awoke Misganaw Temesgen
  • Glob Health Action.2020 Dec;13(1):1776507. doi: 10.1080/16549716.2020.1776507.

複合ヘテロ接合性ACADVL変異による超長鎖アシル-CoAデヒドロゲナーゼ欠損症を呈した成人発症反復性横紋筋融解症の一例

A Case of Adult-onset Repeat Rhabdomyolysis with a Very Long-chain Acyl-CoA Dehydrogenase Deficiency Due to Compound Heterozygous ACADVL Mutations.
  • Yasuhiro Fuseya
  • Takeyo Sakurai
  • Jun-Ichi Miyahara
  • Kei Sato
  • Seiji Kaji
  • Yoshihiko Saito
  • Makio Takahashi
  • Ichizo Nishino
  • Tokiko Fukuda
  • Hideo Sugie
  • Hirofumi Yamashita
  • Intern. Med..2020 Jul;doi: 10.2169/internalmedicine.4604-20.Epub 2020-07-14.

ゼブラフィッシュにおけるスピラントールおよびスピラントールの花のヒドロエタンノール抽出物の生殖毒性。インビボおよびインシリコ評価

Reproductive toxicity of the hydroethanolic extract of the flowers of and spilanthol in zebrafish: In vivo and in silico evaluation.
  • G C de Souza
  • M D Viana
  • Ldm Goés
  • B L Sanchez-Ortiz
  • Ga da Silva
  • Wb de Souza Pinheiro
  • Cb Rodrigues Dos Santos
  • Jc Tavares Carvalho
  • Hum Exp Toxicol.2020 Feb;39(2):127-146. doi: 10.1177/0960327119878257.Epub 2019-10-09.

セカンドスクリーンで測定した新生児スクリーニングの分析物とテキサス州のメディケイド集団における小児自閉症との関連

The association between newborn screening analytes as measured on a second screen and childhood autism in a Texas Medicaid population.
  • Peter H Langlois
  • Mark A Canfield
  • Gary W Rutenberg
  • Dorothy J Mandell
  • Fei Hua
  • Brendan Reilly
  • Duke J Ruktanonchai
  • Janice F Jackson
  • Patricia Hunt
  • Debra Freedenberg
  • Rachel Lee
  • John F Villanacci
  • Am. J. Med. Genet. B Neuropsychiatr. Genet..2020 Jul;doi: 10.1002/ajmg.b.32804.Epub 2020-07-13.

関節鏡下五十肩手術後の疼痛コントロールのための超音波ガイド下勃起筋ブロックと肩関節周囲麻酔薬浸潤の無作為化比較試験。スタディプロトコール臨床試験（SPIRIT準拠）

Randomized control trial of ultrasound-guided erector spinae block versus shoulder periarticular anesthetic infiltration for pain control after arthroscopic shoulder surgery: Study protocol clinical trial (SPIRIT compliant).
  • Mark Czuczman
  • Harsha Shanthanna
  • Bashar Alolabi
  • Peter Moisiuk
  • Turlough O'Hare
  • Moin Khan
  • Mauricio Forero
  • Kimberly Davis
  • Jaydeep Moro
  • Thuva Vanniyasingam
  • Lehana Thabane
  • Medicine (Baltimore).2020 Apr;99(15):e19721. 00005792-202004100-00038. doi: 10.1097/MD.0000000000019721.

中国における省レベルでの土壌重金属汚染の現状、空間的特徴、健康リスク、潜在的な推進要因

Current status, spatial features, health risks, and potential driving factors of soil heavy metal pollution in China at province level.
  • Bifeng Hu
  • Shuai Shao
  • Hao Ni
  • Zhiyi Fu
  • Linshu Hu
  • Yin Zhou
  • Xiaoxiao Min
  • Shufeng She
  • Songchao Chen
  • Mingxiang Huang
  • Lianqing Zhou
  • Yan Li
  • Zhou Shi
  • Environ. Pollut..2020 Jun;266(Pt 3):114961. S0269-7491(20)31276-8. doi: 10.1016/j.envpol.2020.114961.Epub 2020-06-09.

びまん性大細胞型B細胞リンパ腫患者のキャッスルマン病を背景とした濾胞性樹状細胞腫瘍。F-FDG PET/CTによる診断と経過観察

Follicular dendritic cell tumor in the context of a Castleman disease in a patient with Diffuse Large B Cell Lymphoma: Diagnosis and follow-up with F-FDG PET/CT.
  • M Negre Busó
  • E Balliu Collgrós
  • N Ferran Sureda
  • M Velasco Nuño
  • J M Roncero Vidal
  • A Rubió Rodríguez
  • Rev Esp Med Nucl Imagen Mol.2020 Jul;S2253-654X(20)30099-8. doi: 10.1016/j.remn.2020.06.011.Epub 2020-07-03.

自動サンプリングと18Sメタバーコーディングを用いて、春の開花の終わりのHelgoland Roadsで微生物群集の複雑な動態を解明する

Uncovering the intricacies of microbial community dynamics at Helgoland Roads at the end of a spring bloom using automated sampling and 18S meta-barcoding.
  • Katja Metfies
  • Johanna Hessel
  • Robin Klenk
  • Wilhelm Petersen
  • Karen Helen Wiltshire
  • Alexandra Kraberg
  • PLoS ONE.2020;15(6):e0233921. PONE-D-20-02434. doi: 10.1371/journal.pone.0233921.Epub 2020-06-22.

閉塞性肥大型心筋症患者における中隔膜切除術後の大動脈逆流に対する経カテーテル大動脈弁置換術

Transcatheter aortic valve replacement for aortic regurgitation after septal myectomy in patients with obstructive hypertrophic cardiomyopathy.
  • Domitilla Russo
  • Maria Beatrice Musumeci
  • Roberto Nerla
  • Luca Rosario Limite
  • Luca Arcari
  • Matteo Casenghi
  • Fausto Castriota
  • Camillo Autore
  • Cardiovasc Revasc Med.2020 Jun;S1553-8389(20)30359-6. doi: 10.1016/j.carrev.2020.06.010.Epub 2020-06-15.

直腸癌に対するロボット支援と腹腔鏡下切除術の臨床的、病理学的、腫瘍学的転帰。ランダム化比較試験のメタアナリシス

Clinical, pathological, and oncologic outcomes of robotic-assisted versus laparoscopic proctectomy for rectal cancer: A meta-analysis of randomized controlled studies.
  • Caiwen Han
  • Peijing Yan
  • Wutang Jing
  • Meixuan Li
  • Binbin Du
  • Moubo Si
  • Jia Yang
  • Kehu Yang
  • Hui Cai
  • Tiankang Guo
  • Asian J Surg.2020 Jan;S1015-9584(19)30834-6. doi: 10.1016/j.asjsur.2019.11.003.Epub 2020-01-18.

カメルーンのHIV感染者と暮らす女性における高悪性度子宮頸部異常の検出のためのスクリーニング検査の比較

A comparison of screening tests for detection of high-grade cervical abnormalities in women living with HIV from Cameroon.
  • Philip E Castle
  • Rogers Ajeh
  • Anastase Dzudie
  • Ernestine Kendowo
  • Norbert Fuhngwa
  • Andre Gaetan Simo-Wambo
  • Denis Nsame
  • Enow Orock
  • Tiffany M Hebert
  • Amanda J Pierz
  • Daniel Murokora
  • Kathryn Anastos
  • Adebola Adedimeji
  • Infect. Agents Cancer.2020;15:45. 311. doi: 10.1186/s13027-020-00311-w.Epub 2020-07-11.

COVID-19を有する機械換気患者に対するトシリズマブの投与

Tocilizumab for treatment of mechanically ventilated patients with COVID-19.
  • Emily C Somers
  • Gregory A Eschenauer
  • Jonathan P Troost
  • Jonathan L Golob
  • Tejal N Gandhi
  • Lu Wang
  • Nina Zhou
  • Lindsay A Petty
  • Ji Hoon Baang
  • Nicholas O Dillman
  • David Frame
  • Kevin S Gregg
  • Dan R Kaul
  • Jerod Nagel
  • Twisha S Patel
  • Shiwei Zhou
  • Adam S Lauring
  • David A Hanauer
  • Emily Martin
  • Pratima Sharma
  • Christopher M Fung
  • Jason M Pogue
  • Clin. Infect. Dis..2020 Jul;ciaa954. doi: 10.1093/cid/ciaa954.Epub 2020-07-11.

徐放性ポロキサマー407ゲル製剤中のブトルファノール酒石酸塩またはブトルファノール酒石酸塩のオレンジ翅のアマゾンオウムに対する皮下投与による熱性抗侵害受容性効果の評価（）

Evaluation of the thermal antinociceptive effects of subcutaneous administration of butorphanol tartrate or butorphanol tartrate in a sustained-release poloxamer 407 gel formulation to orange-winged Amazon parrots ().
  • Delphine Laniesse
  • David Sanchez-Migallon Guzman
  • Dale A Smith
  • Jamie M Douglas
  • Cornelia Mosley
  • Hugues Beaufrère
  • Joanne Paul-Murphy
  • Am. J. Vet. Res..2020 Jul;81(7):543-550. doi: 10.2460/ajvr.81.7.543.

腸内リンパフロー、脂質と薬物輸送のスケールは、前臨床種からヒトまでアロメトリックに

Intestinal Lymph Flow, and Lipid and Drug Transport Scale Allometrically From Pre-clinical Species to Humans.
  • Natalie L Trevaskis
  • Given Lee
  • Alistair Escott
  • Kian Liun Phang
  • Jiwon Hong
  • Enyuan Cao
  • Kasiram Katneni
  • Susan A Charman
  • Sifei Han
  • William N Charman
  • Anthony R J Phillips
  • John A Windsor
  • Christopher J H Porter
  • Front Physiol.2020;11:458. doi: 10.3389/fphys.2020.00458.Epub 2020-05-21.

哺乳類における正の多様化選択のための遺伝子の適応的分子進化

Adaptive Molecular Evolution of Gene for Positive Diversifying Selection in Mammals.
  • Farmanullah
  • Seyed Mahdi Hosseini
  • Aixin Liang
  • Guohua Hua
  • Zia Ur Rehman
  • Hira Sajjad Talpur
  • Mohammad Salim
  • Saeed Ahmad
  • Adili Abulaiti
  • Momen Khan
  • Muhammad Safdar
  • Ihsan Ullah Kakar
  • Zahoor Ahmad
  • Muhammad Zulfiqar Ahmad
  • Ye Tingzhu
  • Nicola M Schreurs
  • Iqra Bano
  • Liguo Yang
  • Biomed Res Int.2020;2020:2584627. doi: 10.1155/2020/2584627.Epub 2020-05-19.

孤立性甲状腺結節の大きさ、術前の微細針吸引細胞診、凍結切片による治療：レトロスペクティブな単一施設研究

Treatment of solitary thyroid nodules according to size, preoperative fine-needle aspiration cytology and frozen section: a retrospective single centre study.
  • Apostolos C Agrafiotis
  • Youri Sokolow
  • Maria Ruiz-Patino
  • Nicky D'Haene
  • Isabelle Salmon
  • Bernard Corvilain
  • Matteo Cappello
  • Acta Chir. Belg..2019 Oct;119(5):294-302. doi: 10.1080/00015458.2018.1527566.Epub 2019-01-07.

炭酸脱水酵素III阻害剤としての2,4,5-三置換チアゾールの合成と評価

Synthesis and evaluation of 2,4,5-trisubstitutedthiazoles as carbonic anhydrase-III inhibitors.
  • Bilal A Al-Jaidi
  • Pran Kishore Deb
  • Soha Taher Telfah
  • Abdel Naser Dakkah
  • Yazan A Bataineh
  • Qutaiba Ahmed Al Khames Aga
  • Mohammad A Al-Dhoun
  • Ala' Ali Ahmad Al-Subeihi
  • Haifa'a Marouf Odetallah
  • Sanaa K Bardaweel
  • Raghuprasad Mailavaram
  • Katharigatta N Venugopala
  • Anroop B Nair
  • J Enzyme Inhib Med Chem.2020 Dec;35(1):1483-1490. doi: 10.1080/14756366.2020.1786820.

P2Y受容体は、ヌクレオチド誘導EGFRリン酸化を媒介し、頭頸部扁平上皮癌細胞株の増殖と腫瘍形成を刺激する

P2Y receptors mediate nucleotide-induced EGFR phosphorylation and stimulate proliferation and tumorigenesis of head and neck squamous cell carcinoma cell lines.
  • Lucas T Woods
  • Kimberly J Jasmer
  • Kevin Muñoz Forti
  • Vinit C Shanbhag
  • Jean M Camden
  • Laurie Erb
  • Michael J Petris
  • Gary A Weisman
  • Oral Oncol..2020 Jun;109:104808. S1368-8375(20)30244-X. doi: 10.1016/j.oraloncology.2020.104808.Epub 2020-06-12.

家族性高コレステロール血症が疑われる患者における冠動脈疾患とリスク関連LPAバリアント、rs3798220とrs10455872

Coronary artery disease and the risk-associated LPA variants, rs3798220 and rs10455872, in patients with suspected familial hypercholesterolaemia.
  • Michael M Page
  • Katrina L Ellis
  • Jing Pang
  • Dick C Chan
  • Amanda J Hooper
  • Damon A Bell
  • John R Burnett
  • Gerald F Watts
  • Clin. Chim. Acta.2020 Jul;S0009-8981(20)30353-3. doi: 10.1016/j.cca.2020.07.029.Epub 2020-07-15.

マクロフィロフラボンマルトからの新しいビフラボノイド。(Clusiaceae)の抗菌、抗酸化、抗2型糖尿病活性のための新しいビフラボノイド

Macrophylloflavone: A New Biflavonoid from Mart. (Clusiaceae) for Antibacterial, Antioxidant, and Anti-Type 2 Diabetes Mellitus Activities.
  • Hawa Purnama Celala Ary Cane
  • Nurdin Saidi
  • Mustanir Yahya
  • Darusman Darusman
  • Erlidawati Erlidawati
  • Safrida Safrida
  • Musri Musman
  • ScientificWorldJournal.2020;2020:2983129. doi: 10.1155/2020/2983129.Epub 2020-05-12.

微細藻類クロレラの細胞生存率、色素含量、酸化ストレスおよび超微細構造変化の解析による、各種ポリスチレン系マイクロおよびナノプラスチックの毒性効果の検討

Investigation of the toxic effects of different polystyrene micro-and nanoplastics on microalgae Chlorella vulgaris by analysis of cell viability, pigment content, oxidative stress and ultrastructural changes.
  • Layla J Hazeem
  • Gamze Yesilay
  • Mohamed Bououdina
  • Simone Perna
  • Demet Cetin
  • Zekiye Suludere
  • Alexandre Barras
  • Rabah Boukherroub
  • Mar. Pollut. Bull..2020 Jul;156:111278. S0025-326X(20)30396-9. doi: 10.1016/j.marpolbul.2020.111278.Epub 2020-05-22.

クマリン-1,2,3-トリアゾール-アセトアミドハイブリッド誘導体の合成、キャラクタリゼーション、分子ドッキング、および生物活性

Synthesis, characterization, molecular docking, and biological activities of coumarin-1,2,3-triazole-acetamide hybrid derivatives.
  • Nima Sepehri
  • Maryam Mohammadi-Khanaposhtani
  • Nafise Asemanipoor
  • Samanesadat Hosseini
  • Mahmood Biglar
  • Bagher Larijani
  • Mohammad Mahdavi
  • Haleh Hamedifar
  • Parham Taslimi
  • Nastaran Sadeghian
  • Ilhami Gulcin
  • Arch. Pharm. (Weinheim).2020 Jul;:e2000109. doi: 10.1002/ardp.202000109.Epub 2020-07-09.

スフェロイドあたりの細胞数とナノワイヤーの電気伝導率は、シリコンナノワイヤードヒト心臓スフェロイドの機能に影響を与えます

Cell number per spheroid and electrical conductivity of nanowires influence the function of silicon nanowired human cardiac spheroids.
  • Yu Tan
  • Dylan Richards
  • Robert C Coyle
  • Jenny Yao
  • Ruoyu Xu
  • Wenyu Gou
  • Hongjun Wang
  • Donald R Menick
  • Bozhi Tian
  • Ying Mei
  • Acta Biomater.2017 03;51:495-504. S1742-7061(17)30029-6. doi: 10.1016/j.actbio.2017.01.029.Epub 2017-01-10.

抗生物質/遺伝子デリバリーシステムと診断のための標的化コンポーネントとしてのアプタマーハイブリッドナノコンプレックス。A Review

Aptamer Hybrid Nanocomplexes as Targeting Components for Antibiotic/Gene Delivery Systems and Diagnostics: A Review.
  • Navid Rabiee
  • Sepideh Ahmadi
  • Zeynab Arab
  • Mojtaba Bagherzadeh
  • Moein Safarkhani
  • Behzad Nasseri
  • Mohammad Rabiee
  • Mohammadreza Tahriri
  • Thomas J Webster
  • Lobat Tayebi
  • Int J Nanomedicine.2020;15:4237-4256. 248736. doi: 10.2147/IJN.S248736.Epub 2020-06-17.

抑うつ症状に対するスマートフォンベースの生態学的瞬間評価の有用性

The utility of smartphone-based, ecological momentary assessment for depressive symptoms.
  • Samantha J Yim
  • Leanna M W Lui
  • Yena Lee
  • Joshua D Rosenblat
  • Renee-Marie Ragguett
  • Caroline Park
  • Mehala Subramaniapillai
  • Bing Cao
  • Aileen Zhou
  • Carola Rong
  • Kangguang Lin
  • Roger C Ho
  • Alexandria S Coles
  • Amna Majeed
  • Elizabeth R Wong
  • Lee Phan
  • Flora Nasri
  • Roger S McIntyre
  • J Affect Disord.2020 Sep;274:602-609. S0165-0327(19)32809-5. doi: 10.1016/j.jad.2020.05.116.Epub 2020-05-25.

腫瘍摘出術時に放射線不透過性ハイドロゲルを注入することで、補助放射線治療の目標定義が改善されます

Injection of radiopaque hydrogel at time of lumpectomy improves the target definition for adjuvant radiotherapy.
  • Gerson M Struik
  • Nienke Hoekstra
  • Taco M Klem
  • Ali Ghandi
  • Gerda M Verduijn
  • Annemarie T Swaak-Kragten
  • Alja Schoonbeek
  • Kim C de Vries
  • Margriet A Sattler
  • Kees Verhoef
  • Erwin Birnie
  • Jean-Philippe Pignol
  • Radiother Oncol.2019 02;131:8-13. S0167-8140(18)33584-9. doi: 10.1016/j.radonc.2018.11.003.Epub 2018-12-17.

卵巣BDNFは、p53変異卵管上皮細胞に由来する腫瘍前駆体の生存、遊走、および付着を促進する

Ovarian BDNF promotes survival, migration, and attachment of tumor precursors originated from p53 mutant fallopian tube epithelial cells.
  • Min Kang
  • Kay Yi Chong
  • Tobias M P Hartwich
  • Fangfang Bi
  • Allyson K Witham
  • David Patrick
  • Madeline J Morrisson
  • Sarah L Cady
  • Alexandra P Cerchia
  • Dawn Kelk
  • Yifei Liu
  • Jonah Nucci
  • Oluwagbemisola Madarikan
  • Daiki Ueno
  • Brian M Shuch
  • Yang Yang-Hartwich
  • Oncogenesis.2020 May;9(5):55. 10.1038/s41389-020-0243-y. doi: 10.1038/s41389-020-0243-y.Epub 2020-05-29.

重度の治療抵抗性うつ病における反復的経頭蓋磁気刺激の標準的な4週間プロトコルの無作為化比較試験

A randomized controlled trial of a standard 4-week protocol of repetitive transcranial magnetic stimulation in severe treatment resistant depression.
  • P F P van Eijndhoven
  • J Bartholomeus
  • M Möbius
  • A de Bruijn
  • G R A Ferrari
  • P Mulders
  • A H Schene
  • D J L G Schutter
  • J Spijker
  • I Tendolkar
  • J Affect Disord.2020 Sep;274:444-449. S0165-0327(20)30235-4. doi: 10.1016/j.jad.2020.05.055.Epub 2020-05-26.

間葉系幹細胞由来製剤「Exo-d-MAPPS」の慢性気道炎症抑制効果の分子・細胞機構の解明

Molecular and Cellular Mechanisms Responsible for Beneficial Effects of Mesenchymal Stem Cell-Derived Product "Exo-d-MAPPS" in Attenuation of Chronic Airway Inflammation.
  • Carl Randall Harrell
  • Dragica Miloradovic
  • Ruxana Sadikot
  • Crissy Fellabaum
  • Bojana Simovic Markovic
  • Dragana Miloradovic
  • Aleksandar Acovic
  • Valentin Djonov
  • Nebojsa Arsenijevic
  • Vladislav Volarevic
  • Anal Cell Pathol (Amst).2020;2020:3153891. doi: 10.1155/2020/3153891.Epub 2020-03-20.

創傷被覆用エレクトロスピンポリカプロラクトン/グラフェンオキサイド/クエルセチンナノ繊維状足場。生物学的および構造的特性の評価

Electrospun poly-caprolactone/graphene oxide/quercetin nanofibrous scaffold for wound dressing: Evaluation of biological and structural properties.
  • Soraya Faraji
  • Nona Nowroozi
  • Amideddin Nouralishahi
  • Javad Shabani Shayeh
  • Life Sci..2020 Jul;257:118062. S0024-3205(20)30813-4. doi: 10.1016/j.lfs.2020.118062.Epub 2020-07-09.

Study of Women's Health Across the Nation（SWAN）では、多次元的な睡眠健康は断面的にも縦断的にも脂肪率と関連していない

Multidimensional sleep health is not cross-sectionally or longitudinally associated with adiposity in the Study of Women's Health Across the Nation (SWAN).
  • Marissa A Bowman
  • Ryan C Brindle
  • Hadine Joffe
  • Christopher E Kline
  • Daniel J Buysse
  • Bradley M Appelhans
  • Howard M Kravitz
  • Karen A Matthews
  • Genevieve S Neal-Perry
  • Robert T Krafty
  • Martica H Hall
  • Sleep Health.2020 Jul;S2352-7218(20)30129-7. doi: 10.1016/j.sleh.2020.04.014.Epub 2020-07-14.

テストステロン値およびステロイド 5-α-リダクターゼ 2 多型とオピオイド渇望との関連

Association of Testosterone Levels and Steroid 5-Alpha-Reductase 2 Polymorphisms with Opioid Craving.
  • Eva Janke
  • Adrian Groh
  • Christiane Mühle
  • Kenneth M Dürsteler-MacFarland
  • Gerhard A Wiesbeck
  • Johannes Kornhuber
  • Kirsten Jahn
  • Michael Groeschl
  • Ralf Lichtinghagen
  • Helge Frieling
  • Stefan Bleich
  • Thomas Hillemacher
  • Bernd Lenz
  • Annemarie Heberlein
  • Neuropsychobiology.2020 Jul;:1-10. 000508681. doi: 10.1159/000508681.Epub 2020-07-13.

非増悪性線維芽細胞増殖因子1は、スフィンゴシン-1-リン酸1経路を制御することにより、虚血性脳卒中後の血管新生を促進した

Non-Mitogenic Fibroblast Growth Factor 1 Enhanced Angiogenesis Following Ischemic Stroke by Regulating the Sphingosine-1-Phosphate 1 Pathway.
  • Yuchi Zou
  • Jian Hu
  • Wenting Huang
  • Shasha Ye
  • Fanyi Han
  • Jingting Du
  • Mingjie Shao
  • Ruili Guo
  • Jingjing Lin
  • Yeli Zhao
  • Ye Xiong
  • Xue Wang
  • Front Pharmacol.2020;11:59. doi: 10.3389/fphar.2020.00059.Epub 2020-03-03.

キトサン被覆酸化銅ナノコンポジットの環境生体適合性と抗菌性を向上させた工業用（アゾ）色素の水溶液からの除去

Eco-biocompatibility of chitosan coated biosynthesized copper oxide nanocomposite for enhanced industrial (Azo) dye removal from aqueous solution and antibacterial properties.
  • Selvam Sathiyavimal
  • Seerangaraj Vasantharaj
  • Thamaraiselvi Kaliannan
  • Arivalagan Pugazhendhi
  • Carbohydr Polym.2020 Aug;241:116243. S0144-8617(20)30417-3. doi: 10.1016/j.carbpol.2020.116243.Epub 2020-04-08.

淡水動物プランクトンにおける限られた条件下でのリンの分配と化学量論的調節。淡水動物プランクトンにおけるリンの分配と化学量論的制御：栄養循環への示唆

Allocation and stoichiometric regulation of phosphorus in a freshwater zooplankton under limited conditions: Implication for nutrient cycling.
  • Xuejia He
  • Wen-Xiong Wang
  • Sci. Total Environ..2020 Aug;728:138795. S0048-9697(20)32312-3. doi: 10.1016/j.scitotenv.2020.138795.Epub 2020-04-19.

Rhoeoのペリセントロメアクラスタリングは、ATとGCに富んだヘテロクロマチン画分の自己組織化を含み、発生的に制御されており、分化の過程で増加する

Pericentromere clustering in Tradescantia section Rhoeo involves self-associations of AT- and GC-rich heterochromatin fractions, is developmentally regulated, and increases during differentiation.
  • Hieronim Golczyk
  • Arleta Limanówka
  • Anna Uchman-Książek
  • Chromosoma.2020 Jul;10.1007/s00412-020-00740-x. doi: 10.1007/s00412-020-00740-x.Epub 2020-07-17.

長引く熱性発作の既往を有するてんかんモデルラットのペンチレンテトラゾールを用いた抑うつ様行動におけるグルタミン酸経路の解明

Glutamatergic pathway in depressive-like behavior associated with pentylenetetrazole rat model of epilepsy with history of prolonged febrile seizures.
  • Oluwole Ojo Alese
  • Gwladys Temkou Ngoupaye
  • Cleopatra Rakgantsho
  • Nombuso V Mkhize
  • Simo Zulu
  • Musa V Mabandla
  • Life Sci..2020 Jul;253:117692. S0024-3205(20)30440-9. doi: 10.1016/j.lfs.2020.117692.Epub 2020-05-03.

タバコの煙や炎症性物質への吸入暴露は、肺のエピジェネティックな変化を誘導する

Inhalation exposure to cigarette smoke and inflammatory agents induces epigenetic changes in the lung.
  • Christopher L Seiler
  • J Ung Min Song
  • Delshanee Kotandeniya
  • Jianji Chen
  • Thomas J Y Kono
  • Qiyuan Han
  • Mathia Colwell
  • Benjamin Auch
  • Aaron L Sarver
  • Pramod Upadhyaya
  • Yanan Ren
  • Christopher Faulk
  • Silvio De Flora
  • Sebastiano La Maestra
  • Yue Chen
  • Fekadu Kassie
  • Natalia Y Tretyakova
  • Sci Rep.2020 Jul;10(1):11290. 10.1038/s41598-020-67502-8. doi: 10.1038/s41598-020-67502-8.Epub 2020-07-09.

膵管腺癌における細胞型特異的代謝の解剖

Dissecting cell type-specific metabolism in pancreatic ductal adenocarcinoma.
  • Allison N Lau
  • Zhaoqi Li
  • Laura V Danai
  • Anna M Westermark
  • Alicia M Darnell
  • Raphael Ferreira
  • Vasilena Gocheva
  • Sharanya Sivanand
  • Evan C Lien
  • Kiera M Sapp
  • Jared R Mayers
  • Giulia Biffi
  • Christopher R Chin
  • Shawn M Davidson
  • David A Tuveson
  • Tyler Jacks
  • Nicholas J Matheson
  • Omer Yilmaz
  • Matthew G Vander Heiden
  • Elife.2020 Jul;9. e56782. doi: 10.7554/eLife.56782.Epub 2020-07-10.

FADS1とELOVL2の遺伝子変異は、アラキドン酸のレベルとチュニジアの人口におけるアルツハイマー病のリスクを増加させる

Genetic variants in FADS1 and ELOVL2 increase level of arachidonic acid and the risk of Alzheimer's disease in the Tunisian population.
  • Souha Hammouda
  • Imen Ghzaiel
  • Wided Khamlaoui
  • Sonia Hammami
  • Samia Younes Mhenni
  • Slim Samet
  • Mohamed Hammami
  • Amira Zarrouk
  • Prostaglandins Leukot. Essent. Fatty Acids.2020 Jul;160:102159. S0952-3278(20)30117-4. doi: 10.1016/j.plefa.2020.102159.Epub 2020-07-04.

選択的セロトニン再取り込み阻害薬（SSRI）は、神経芽腫腫瘍の取り込みに影響を与えることなく、血小板中のメタヨードベンジルグアニジン（MIBG）の取り込みを抑制した

Selective serotonin reuptake inhibitors (SSRIs) prevent meta-iodobenzylguanidine (MIBG) uptake in platelets without affecting neuroblastoma tumor uptake.
  • Thomas Blom
  • Rutger Meinsma
  • Marja Rutgers
  • Corine Buitenhuis
  • Marieke Dekken-Van den Burg
  • André B P van Kuilenburg
  • Godelieve A M Tytgat
  • EJNMMI Res.2020 Jul;10(1):78. 10.1186/s13550-020-00662-w. doi: 10.1186/s13550-020-00662-w.Epub 2020-07-08.

ステロール14α-デメチラーゼ（CYP51）を標的とした低分子阻害剤。カンジダアルビカンスに対する合成、分子モデル化、評価

Small-Molecule Inhibitors Targeting Sterol 14α-Demethylase (CYP51): Synthesis, Molecular Modelling and Evaluation Against Candida albicans.
  • Faizah A Binjubair
  • Josie E Parker
  • Andrew G Warrilow
  • Kalika Puri
  • Peter J Braidley
  • Esra Tatar
  • Steven L Kelly
  • Diane E Kelly
  • Claire Simons
  • ChemMedChem.2020 May;doi: 10.1002/cmdc.202000250.Epub 2020-05-27.

ブラジル北東部のコミュニティにおける土壌伝染性蠕虫症に対する学校ベースの大規模治療後の腸内寄生虫の疫学的プロファイルの変化。STHに対する学校ベースの大規模治療後の疫学的プロファイル．

Changes in the epidemiological profile of intestinal parasites after a school-based large-scale treatment for soil-transmitted helminths in a community in northeastern Brazil: Epidemiological profile after large-scale school-based treatment for STH.
  • Yvanna L D C Oliveira
  • Luciana M Oliveira
  • Yrna L M Oliveira
  • Ana M D Nascimento
  • Roseli La Corte
  • Ricardo M Geraldi
  • Luciene Barbosa
  • Pedro H Gazzinelli-Guimarães
  • Ricardo T Fujiwara
  • Lilian L Bueno
  • Silvio S Dolabella
  • Acta Trop..2020 Feb;202:105279. S0001-706X(19)30990-8. doi: 10.1016/j.actatropica.2019.105279.Epub 2019-11-21.

腹腔鏡下スリーブ胃切除術前および後期（10.5年）の食道遠位部および胃における臨床的、内視鏡的、組織学的所見。93％の追跡調査を行ったプロスペクティブ研究の結果

Clinical, Endoscopic, and Histologic Findings at the Distal Esophagus and Stomach Before and Late (10.5 Years) After Laparoscopic Sleeve Gastrectomy: Results of a Prospective Study with 93% Follow-Up.
  • Attila Csendes
  • Omar Orellana
  • Gustavo Martínez
  • Ana María Burgos
  • Manuel Figueroa
  • Enrique Lanzarini
  • Obes Surg.2019 12;29(12):3809-3817. 10.1007/s11695-019-04054-5. doi: 10.1007/s11695-019-04054-5.

電位差測定におけるグラフェンナノプレート。ナノコンポジットカーボンペーストとPVCベースの膜センサーを用いた、血漿および牛乳サンプル中のVilazodone HClの分析

Graphene nanoplatelets in potentiometry: A nanocomposite carbon paste and PVC based membrane sensors for analysis of Vilazodone HCl in plasma and milk samples.
  • Amira M El-Kosasy
  • Mona Hamdy Abdel Rahman
  • Sarah H Abdelaal
  • Talanta.2019 Feb;193:9-14. S0039-9140(18)31009-9. doi: 10.1016/j.talanta.2018.09.091.Epub 2018-09-25.

脳血行動態摂動モデルにおける脳自己調節の評価のための経眼的脳インピーダンス指標

Trans-ocular brain impedance index for assessment of cerebral autoregulation in a porcine model of cerebral hemodynamic perturbation.
  • Mohamad H Tiba
  • Brendan M McCracken
  • Danielle C Leander
  • Carmen I Colmenero
  • Brandon C Cummings
  • Nicholas L Greer
  • Paul Picton
  • Craig A Williamson
  • Kevin R Ward
  • J Clin Monit Comput.2020 Jul;10.1007/s10877-020-00556-1. doi: 10.1007/s10877-020-00556-1.Epub 2020-07-14.

ナシ（Nakai cv. Nijisseiki）果汁濃縮物から精製した5-ヒドロキシメチル-2-フラルデヒドは、B16マウスメラノーマ細胞のメラニン生成を抑制する

5-hydroxymethyl-2-furaldehyde purified from Japanese pear ( Nakai cv. Nijisseiki) juice concentrate inhibits melanogenesis in B16 mouse melanoma cells.
  • Tomohiro Bito
  • Kyohei Koseki
  • Ryota Asano
  • Nakaba Ueda
  • Takuhiro Yamada
  • Yukinori Yabuta
  • Tsuyoshi Ichiyanagi
  • Atsushi Ishihara
  • Kishi Watanabe
  • Fumio Watanabe
  • Biosci. Biotechnol. Biochem..2020 Jul;:1-11. doi: 10.1080/09168451.2020.1792762.Epub 2020-07-16.

腫瘍リウマチ学：悪性腫瘍と筋骨格系疾患の関係

Oncorheumatology: relationship between malignancies and musculoskeletal diseases
  • Zoltán Szekanecz
  • Izabella Gomez
  • Boglárka Soós
  • Levente Bodoki
  • Szilvia Szamosi
  • Csilla András
  • Balázs Juhász
  • László Váróczy
  • Péter Antal-Szalmás
  • Péter Szodoray
  • Nóra Bittner
  • Péter Árkosy
  • Árpád Illés
  • Gabriella Szűcs
  • Katalin Dankó
  • Tamás Bender
  • László Tamási
  • Éva Szekanecz
  • Orv Hetil.2020 07;161(28):1151-1165. doi: 10.1556/650.2020.31800.

Averrhoa bilimbiペクチンベースの食用フィルム。ペクチンの直線性と分岐性がフィルムの物理化学的、機械的、バリア性に及ぼす影響

Averrhoa bilimbi pectin-based edible films: Effects of the linearity and branching of the pectin on the physicochemical, mechanical, and barrier properties of the films.
  • Muhammad Hakimin Shafie
  • Rizana Yusof
  • Dalina Samsudin
  • Chee-Yuen Gan
  • Int. J. Biol. Macromol..2020 Jul;S0141-8130(20)33863-0. doi: 10.1016/j.ijbiomac.2020.07.109.Epub 2020-07-13.

新石器時代の中央ヨーロッパにおける家猫の祖先：シナントロピー的な食生活を示す同位体比の証拠

Ancestors of domestic cats in Neolithic Central Europe: Isotopic evidence of a synanthropic diet.
  • Magdalena Krajcarz
  • Maciej T Krajcarz
  • Mateusz Baca
  • Chris Baumann
  • Wim Van Neer
  • Danijela Popović
  • Magdalena Sudoł-Procyk
  • Bartosz Wach
  • Jarosław Wilczyński
  • Michał Wojenka
  • Hervé Bocherens
  • Proc. Natl. Acad. Sci. U.S.A..2020 Jul;201918884. doi: 10.1073/pnas.1918884117.Epub 2020-07-13.

ヨウ素化造影剤に対する過敏症反応のアレルギー評価のための非経口チャレンジ試験における造影誘発性腎症を予防するためのプロトコール

Protocol to prevent contrast-induced nephropathy in parenteral challenge-tests for allergy evaluation of hypersensitivity reactions to iodinated contrast media.
  • Francisco Vega
  • M Victoria Múgica
  • Laura Argíz
  • Raphaëlle Bazire
  • M Teresa Belver
  • Alfonsa Friera
  • Carlos Blanco
  • Clin. Exp. Allergy.2020 Jul;doi: 10.1111/cea.13709.Epub 2020-07-11.

ロボット支援下の根治的膀胱摘出術における体腔内同所性回腸新膀胱を用いた後方再建術：簡単なステップの説明と結果

Posterior reconstruction during robotic-assisted radical cystectomy with intracorporeal orthotopic ileal neobladder: description and outcomes of a simple step.
  • Bernardo Rocco
  • Lorenzo G Luciani
  • Justin Collins
  • Rodolfo Sanchez-Salas
  • Christofer Adding
  • Daniele Mattevi
  • Abolfazl Hosseini
  • Peter Wiklund
  • J Robot Surg.2020 Jun;10.1007/s11701-020-01108-0. doi: 10.1007/s11701-020-01108-0.Epub 2020-06-29.

微小血管バリア機能の維持には、CD31受容体誘導代謝リプログラミングが必要である

Preservation of microvascular barrier function requires CD31 receptor-induced metabolic reprogramming.
  • Kenneth C P Cheung
  • Silvia Fanti
  • Claudio Mauro
  • Guosu Wang
  • Anitha S Nair
  • Hongmei Fu
  • Silvia Angeletti
  • Silvia Spoto
  • Marta Fogolari
  • Francesco Romano
  • Dunja Aksentijevic
  • Weiwei Liu
  • Baiying Li
  • Lixin Cheng
  • Liwen Jiang
  • Juho Vuononvirta
  • Thanushiyan R Poobalasingam
  • David M Smith
  • Massimo Ciccozzi
  • Egle Solito
  • Federica M Marelli-Berg
  • Nat Commun.2020 Jul;11(1):3595. 10.1038/s41467-020-17329-8. doi: 10.1038/s41467-020-17329-8.Epub 2020-07-17.

MSにおけるCOVID-19のアウトカム。NYU多発性硬化症包括ケアセンターからの初期経験の観察研究

COVID-19 outcomes in MS: Observational study of early experience from NYU Multiple Sclerosis Comprehensive Care Center.
  • Erica Parrotta
  • Ilya Kister
  • Leigh Charvet
  • Carrie Sammarco
  • Valerie Saha
  • Robert Erik Charlson
  • Jonathan Howard
  • Josef Maxwell Gutman
  • Malcolm Gottesman
  • Nada Abou-Fayssal
  • Robyn Wolintz
  • Marshall Keilson
  • Cristina Fernandez-Carbonell
  • Lauren B Krupp
  • Lana Zhovtis Ryerson
  • Neurol Neuroimmunol Neuroinflamm.2020 09;7(5). e835. doi: 10.1212/NXI.0000000000000835.Epub 2020-07-09.

ネパールにおける成長モニタリングと促進の障壁と促進要因。ネパールにおける成長モニタリングと促進の障壁と促進要因：家庭、保健ワーカー、女性コミュニティ保健ボランティアの認識

Barriers and facilitators to growth monitoring and promotion in Nepal: Household, health worker and female community health volunteer perceptions.
  • Madeline M Pollifrone
  • Kenda Cunningham
  • Pooja Pandey Rana
  • Morgan M Philbin
  • Shraddha Manandhar
  • Krishna P Lamsal
  • Raj Nandan Mandal
  • Vikash Deuja
  • Matern Child Nutr.2020 Jul;:e12999. doi: 10.1111/mcn.12999.Epub 2020-07-12.

ヨルダンの青少年における早期結婚と性暴力・性暴力に関連した研究、政策、保健サービスの提供環境についての社会・生態学的な検討

A social-ecological examination into the research, policy and health service delivery environment related to early marriage and sexual and gender-based violence among youth in Jordan.
  • Jewel Gausman
  • Areej Othman
  • Abeer Dababneh
  • Maysoon Dabobe
  • Iqbal Hamad
  • Insaf Daas
  • Ana Langer
  • BMC Int Health Hum Rights.2020 Jul;20(1):16. 10.1186/s12914-020-00234-y. doi: 10.1186/s12914-020-00234-y.Epub 2020-07-13.

産後期間中の専門的支援：専門的サービスに対する原始母体の母親の見解と期待、専門的支援を利用する上での障壁を明らかにした

Professional support during the postpartum period: primiparous mothers' views on professional services and their expectations, and barriers to utilizing professional help.
  • Yiping Nan
  • Jingjun Zhang
  • Anum Nisar
  • Lanting Huo
  • Lei Yang
  • Juan Yin
  • Duolao Wang
  • Atif Rahman
  • Yan Gao
  • Xiaomei Li
  • BMC Pregnancy Childbirth.2020 Jul;20(1):402. 10.1186/s12884-020-03087-4. doi: 10.1186/s12884-020-03087-4.Epub 2020-07-11.

mepAおよびnorA遺伝子をコードする流出ポンプを過剰発現する黄色ブドウ球菌株におけるオゼノキサシンと他のキノロン類の比較活性

Comparative activity of ozenoxacin and other quinolones in Staphylococcus aureus strains overexpressing the efflux pumps encoding genes mepA and norA.
  • Y López
  • M Tato
  • F D Gargallo-Viola
  • R Cantón
  • J Vila
  • I Zsolt
  • Int. J. Antimicrob. Agents.2020 Jul;:106082. S0924-8579(20)30252-1. doi: 10.1016/j.ijantimicag.2020.106082.Epub 2020-07-10.

エンベロープタンパク質のユビキチン化がジカウイルスの侵入と発症を促進する

Envelope protein ubiquitination drives entry and pathogenesis of Zika virus.
  • Maria I Giraldo
  • Hongjie Xia
  • Leopoldo Aguilera-Aguirre
  • Adam Hage
  • Sarah van Tol
  • Chao Shan
  • Xuping Xie
  • Gail L Sturdevant
  • Shelly J Robertson
  • Kristin L McNally
  • Kimberly Meade-White
  • Sasha R Azar
  • Shannan L Rossi
  • Wendy Maury
  • Michael Woodson
  • Holly Ramage
  • Jeffrey R Johnson
  • Nevan J Krogan
  • Marc C Morais
  • Sonja M Best
  • Pei-Yong Shi
  • Ricardo Rajsbaum
  • Nature.2020 Jul;10.1038/s41586-020-2457-8. doi: 10.1038/s41586-020-2457-8.Epub 2020-07-08.

癌ナノメディシン特集号レビュー ナノ粒子による抗癌剤送達。従来の治療や免疫療法のための治療ツールとしての細胞外ベシクルまたは合成ナノビーズ

Cancer Nanomedicine Special Issue Review Anticancer Drug Delivery with Nanoparticles: Extracellular Vesicles or Synthetic Nanobeads as Therapeutic Tools for Conventional Treatment or Immunotherapy.
  • Maria Raffaella Zocchi
  • Francesca Tosetti
  • Roberto Benelli
  • Alessandro Poggi
  • Cancers (Basel).2020 Jul;12(7). E1886. doi: 10.3390/cancers12071886.Epub 2020-07-13.

マダガスカルとコモロ島の新しい遺伝子型を明らかにした集団ゲノミクス

Population Genomics of Reveals a New Genotype in Madagascar and the Comoros.
  • Charlotte Avanzi
  • Emmanuel Lécorché
  • Fetra Angelot Rakotomalala
  • Andrej Benjak
  • Fahafahantsoa Rapelanoro Rabenja
  • Lala S Ramarozatovo
  • Bertrand Cauchoix
  • Mala Rakoto-Andrianarivelo
  • Maria Tió-Coma
  • Thyago Leal-Calvo
  • Philippe Busso
  • Stefanie Boy-Röttger
  • Aurélie Chauffour
  • Tahinamandrato Rasamoelina
  • Aina Andrianarison
  • Fandresena Sendrasoa
  • John S Spencer
  • Pushpendra Singh
  • Digambar Ramchandra Dashatwar
  • Rahul Narang
  • Jean-Luc Berland
  • Vincent Jarlier
  • Claudio G Salgado
  • Milton O Moraes
  • Annemieke Geluk
  • Andriamira Randrianantoandro
  • Emmanuelle Cambau
  • Stewart T Cole
  • Front Microbiol.2020;11:711. doi: 10.3389/fmicb.2020.00711.Epub 2020-05-11.

ピンナップ類における生態進化のスケールを超えた遺伝的変動の決定要因

Determinants of genetic variation across eco-evolutionary scales in pinnipeds.
  • Claire R Peart
  • Sergio Tusso
  • Saurabh D Pophaly
  • Fidel Botero-Castro
  • Chi-Chih Wu
  • David Aurioles-Gamboa
  • Amy B Baird
  • John W Bickham
  • Jaume Forcada
  • Filippo Galimberti
  • Neil J Gemmell
  • Joseph I Hoffman
  • Kit M Kovacs
  • Mervi Kunnasranta
  • Christian Lydersen
  • Tommi Nyman
  • Larissa Rosa de Oliveira
  • Anthony J Orr
  • Simona Sanvito
  • Mia Valtonen
  • Aaron B A Shafer
  • Jochen B W Wolf
  • Nat Ecol Evol.2020 Jun;10.1038/s41559-020-1215-5. doi: 10.1038/s41559-020-1215-5.Epub 2020-06-08.

脂肪率の上昇に伴う多嚢胞性卵巣症候群は、レプチンやアディポネクチンとは異なるTNF-αおよびIL-6の血清レベルを阻害する

Polycystic ovary syndrome associated with increased adiposity interferes with serum levels of TNF-alpha and IL-6 differently from leptin and adiponectin.
  • Nathália Sigilló Cardoso
  • Victor Barbosa Ribeiro
  • Sabrina Graziani Veloso Dutra
  • Rui Alberto Ferriani
  • Ada Clarice Gastaldi
  • João Eduardo de Araújo
  • Hugo Celso Dutra de Souza
  • Arch Endocrinol Metab.2020 Feb;64(1):4-10. S2359-39972020000100004. doi: 10.20945/2359-3997000000197.Epub 2020-03-13.

ヤギから採取したネコノミ（Ctenocephalides felis）サンプルのパラ遺伝子におけるノックダウン耐性変異の高頻度

High frequency of knockdown resistance mutations in the para gene of cat flea (Ctenocephalides felis) samples collected from goats.
  • Sedef Erkunt Alak
  • Ahmet Efe Köseoğlu
  • Çağrı Kandemir
  • Turğay Taşkın
  • Samiye Demir
  • Mert Döşkaya
  • Cemal Ün
  • Hüseyin Can
  • Parasitol. Res..2020 Jul;119(7):2067-2073. 10.1007/s00436-020-06714-3. doi: 10.1007/s00436-020-06714-3.Epub 2020-05-28.

ポリマーフリーと耐久性のあるポリマー薬剤溶出冠動脈ステントの無作為化試験からの10年間の成績

10-Year Outcomes From a Randomized Trial of Polymer-Free Versus Durable Polymer Drug-Eluting Coronary Stents.
  • Sebastian Kufner
  • Maximilian Ernst
  • Salvatore Cassese
  • Michael Joner
  • Katharina Mayer
  • Roisin Colleran
  • Tobias Koppara
  • Erion Xhepa
  • Tobias Koch
  • Jens Wiebe
  • Tareq Ibrahim
  • Massimiliano Fusaro
  • Karl-Ludwig Laugwitz
  • Heribert Schunkert
  • Adnan Kastrati
  • Robert A Byrne
  • J. Am. Coll. Cardiol..2020 Jul;76(2):146-158. S0735-1097(20)35314-6. doi: 10.1016/j.jacc.2020.05.026.

ボリビアの若い女性の間で効果的な避妊の受け入れと使用を増やすために携帯電話のインスタントメッセージングによって配信された介入。無作為化対照試験

An Intervention Delivered by Mobile Phone Instant Messaging to Increase Acceptability and Use of Effective Contraception Among Young Women in Bolivia: Randomized Controlled Trial.
  • Ona L McCarthy
  • Carolina Aliaga
  • Maria Eugenia Torrico Palacios
  • Jhonny López Gallardo
  • Silvia Huaynoca
  • Baptiste Leurent
  • Phil Edwards
  • Melissa Palmer
  • Irrfan Ahamed
  • Caroline Free
  • J. Med. Internet Res..2020 Jun;22(6):e14073. v22i6e14073. doi: 10.2196/14073.Epub 2020-06-22.

ステロイドのLC/ESI-MS/MSアッセイにおけるスループット向上のための複数の類似試薬を用いた誘導体化によるサンプルの多重化。血漿17α-ヒドロキシプロゲステロンを例に挙げています

Sample-multiplexing by derivatization using multiple analogous reagents for enhancing throughput in LC/ESI-MS/MS assay of steroids: Plasma 17α-hydroxyprogesterone as an example.
  • Miki Kamemura
  • Mai Yokota
  • Shoujiro Ogawa
  • Takahiro Sugiura
  • Tatsuya Higashi
  • J. Chromatogr. B Analyt. Technol. Biomed. Life Sci..2020 Jun;1146:122117. S1570-0232(20)30272-5. doi: 10.1016/j.jchromb.2020.122117.Epub 2020-04-15.

リソソームシアル酸トランスポーターSialinの新しいリガンドとしての芳香族またはヘテロ芳香族置換基を有するアミノ酸

Amino Acids Bearing Aromatic or Heteroaromatic Substituents as a New Class of Ligands for the Lysosomal Sialic Acid Transporter Sialin.
  • Lilian Dubois
  • Nicolas Pietrancosta
  • Alexandre Cabaye
  • Isabelle Fanget
  • Cécile Debacker
  • Pierre-André Gilormini
  • Patrick M Dansette
  • Julien Dairou
  • Christophe Biot
  • Roseline Froissart
  • Anne Goupil-Lamy
  • Hugues-Olivier Bertrand
  • Francine C Acher
  • Isabelle McCort-Tranchepain
  • Bruno Gasnier
  • Christine Anne
  • J. Med. Chem..2020 Jul;doi: 10.1021/acs.jmedchem.9b02119.Epub 2020-07-15.

現代の創薬を支援するためにzileutonとその不純物に関するインシリコ治療と毒性学的プロファイリングと組み合わせた薬剤分析

Pharmaceutical analysis combined with in-silico therapeutic and toxicological profiling on zileuton and its impurities to assist in modern drug discovery.
  • Saurabh B Ganorkar
  • Yvan Vander Heyden
  • Atul A Shirkhedkar
  • Deepak K Lokwani
  • Dinesh M Dhumal
  • Preeti S Bobade
  • J Pharm Biomed Anal.2020 Feb;179:112982. S0731-7085(19)31948-X. doi: 10.1016/j.jpba.2019.112982.Epub 2019-11-15.

妊娠初期および妊娠中期における経口ブドウ糖負荷試験中の代謝物の変化。PEARLS無作為化、制御された生活習慣試験からの知見

Changes in Metabolites During an Oral Glucose Tolerance Test in Early and Mid-Pregnancy: Findings from the PEARLS Randomized, Controlled Lifestyle Trial.
  • Danielle E Haslam
  • Jun Li
  • Liming Liang
  • Marijulie Martinez
  • Cristina Palacios
  • Maria A Trak-Fellermeier
  • Paul W Franks
  • Kaumudi Joshipura
  • Shilpa N Bhupathiraju
  • Metabolites.2020 Jul;10(7). E284. doi: 10.3390/metabo10070284.Epub 2020-07-10.

大西洋中部地域の小さな流域における水生炭素のフラックスと資源量をより正確に定量化するために、河床における土砂の膨張過程をモデル化した

Modeling sediment diagenesis processes on riverbed to better quantify aquatic carbon fluxes and stocks in a small watershed of the Mid-Atlantic region.
  • Junyu Qi
  • Xuesong Zhang
  • Sangchul Lee
  • Yiping Wu
  • Glenn E Moglen
  • Gregory W McCarty
  • Carbon Balance Manag.2020 Jul;15(1):13. 10.1186/s13021-020-00148-1. doi: 10.1186/s13021-020-00148-1.Epub 2020-07-06.

内視鏡的超音波ガイド下細針吸引を用いた膵臓悪性腫瘍の診断における細胞学的製剤と組織学的製剤の比較

Comparison of cytological and histological preparations in the diagnosis of pancreatic malignancies using endoscopic ultrasound-guided fine needle aspiration.
  • Dong Kee Jang
  • Sang Hyub Lee
  • Jun Kyu Lee
  • Woo Hyun Paik
  • Kwang Hyun Chung
  • Ban Seok Lee
  • Jun Hyuk Son
  • Jae Woo Lee
  • Ji Kon Ryu
  • Yong-Tae Kim
  • Kyoung-Bun Lee
  • HBPD INT.2017 Aug;16(4):418-423. S1499-3872(17)60035-3. doi: 10.1016/S1499-3872(17)60035-3.

網膜色素上皮細胞におけるオステオポンチンの浸透圧および低酸素誘導。浸透圧と低酸素による網膜色素上皮細胞におけるオステオポンチンの誘導：プリンリン作動性受容体シグナルの関与

Osmotic and hypoxic induction of osteopontin in retinal pigment epithelial cells: Involvement of purinergic receptor signaling.
  • Margrit Hollborn
  • Ricarda Brück
  • Heidrun Kuhrt
  • Peter Wiedemann
  • Andreas Bringmann
  • Mol. Vis..2020;26:188-203. Epub 2020-03-08.

切除した非小細胞肺癌患者における腫瘍浸潤リンパ球（TIL）の予後予測値、およびそのPD-L1発現およびDNA修復タンパク質RAD51との関連

Prognostic value of tumor-infiltrating lymphocytes (TILs) and their association with PD-L1 expression and DNA repair protein RAD51 in patients with resected non-small cell lung carcinoma.
  • Mariam Gachechiladze
  • Josef Škarda
  • Daniela Skanderová
  • Ivo Überall
  • Vítězslav Kolek
  • Petra Smičkova
  • Petr Vojta
  • Jana Vbrková
  • Marián Hajdúch
  • Ilay Shani
  • Zdeněk Kolář
  • Rolf Stahel
  • Walter Weder
  • Undine Rulle
  • Alex Soltermann
  • Markus Joerger
  • Lung Cancer.2020 Jun;147:30-38. S0169-5002(20)30499-2. doi: 10.1016/j.lungcan.2020.06.025.Epub 2020-06-23.

透視検査を行わない緩和的食道ステント留置術の臨床的有効性と安全性：システマティックレビューとメタアナリシス

Clinical efficacy and safety of palliative esophageal stenting without fluoroscopy: a systematic review and meta-analysis.
  • Saurabh Chandan
  • Babu P Mohan
  • Shahab R Khan
  • Neil Bhogal
  • Andrew Canakis
  • Mohammad Bilal
  • Amaninder S Dhaliwal
  • Muhammad Aziz
  • Harmeet S Mashiana
  • Shailender Singh
  • Wade Lee-Smith
  • Suresh Ponnada
  • Ishfaq Bhat
  • Douglas Pleskow
  • Endosc Int Open.2020 Jul;8(7):E944-E952. doi: 10.1055/a-1164-6398.Epub 2020-06-16.

テロメアの萎縮と機能不全：ナイメーヘン壊死症候群におけるプロジェロイド表現型の潜在的な引き金となる

Telomere attrition and dysfunction: a potential trigger of the progeroid phenotype in nijmegen breakage syndrome.
  • Raneem Habib
  • Ryong Kim
  • Heidemarie Neitzel
  • Ilja Demuth
  • Krystyna Chrzanowska
  • Eva Seemanova
  • Renaldo Faber
  • Martin Digweed
  • Reinhard Voss
  • Kathrin Jäger
  • Karl Sperling
  • Michael Walter
  • Aging (Albany NY).2020 Jun;12(12):12342-12375. 103453. doi: 10.18632/aging.103453.Epub 2020-06-20.

レム睡眠行動障害のバリアント：多施設研究

variants in REM sleep behavior disorder: a multicenter study.
  • Lynne Krohn
  • Jennifer A Ruskey
  • Uladzislau Rudakou
  • Etienne Leveille
  • Farnaz Asayesh
  • Michele T M Hu
  • Isabelle Arnulf
  • Yves Dauvilliers
  • Birgit Högl
  • Ambra Stefani
  • Christelle Charley Monaca
  • Abril Beatriz
  • Giuseppe Plazzi
  • Elena Antelmi
  • Luigi Ferini-Strambi
  • Anna Heidbreder
  • Bradley F Boeve
  • Alberto J Espay
  • Valérie Cochen De Cock
  • Brit Mollenhauer
  • Friederike Sixel-Döring
  • Claudia Trenkwalder
  • Karel Sonka
  • David Kemlink
  • Michela Figorilli
  • Monica Puligheddu
  • Femke Dijkstra
  • Mineke Viaene
  • Wolfgang Oertel
  • Marco Toffoli
  • Gian Luigi Gigli
  • Mariarosaria Valente
  • Jean-François Gagnon
  • Alex Desautels
  • Jacques Y Montplaisir
  • Ronald B Postuma
  • Guy A Rouleau
  • Ziv Gan-Or
  • Neurology.2020 Jun;10.1212/WNL.0000000000010042. doi: 10.1212/WNL.0000000000010042.Epub 2020-06-26.

悪性閉塞の緩和を目的とした新たに設計されたアンカバード胆道ステント：前向き研究の結果

A newly designed uncovered biliary stent for palliation of malignant obstruction: results of a prospective study.
  • Christopher Lawrence
  • Jose Nieto
  • Willis G Parsons
  • André Roy
  • Nalini M Guda
  • Stephen E Steinberg
  • Muhammad K Hasan
  • Juan Carlos Bucobo
  • Satish Nagula
  • Nicholas D Dey
  • Jonathan M Buscaglia
  • BMC Gastroenterol.2020 Jun;20(1):184. 10.1186/s12876-020-01325-9. doi: 10.1186/s12876-020-01325-9.Epub 2020-06-10.

HPVワクチン接種。イタリアコルポスコピー・子宮頸管・膣病理学会（SICPCV）のポジションペーパー

HPV Vaccination: The Position Paper of the Italian Society of Colposcopy and Cervico-Vaginal Pathology (SICPCV).
  • Andrea Ciavattini
  • Luca Giannella
  • Rosa De Vincenzo
  • Jacopo Di Giuseppe
  • Maria Papiccio
  • Ankica Lukic
  • Giovanni Delli Carpini
  • Antonio Perino
  • Antonio Frega
  • Francesco Sopracordevole
  • Maggiorino Barbero
  • Murat Gultekin
  • Vaccines (Basel).2020 Jul;8(3). E354. doi: 10.3390/vaccines8030354.Epub 2020-07-02.

Zophobas atratus（Coleoptera: Tenebrionidae）の幼虫であるスーパーワームにおける低密度ポリエチレンとポリスチレンの生分解。広範囲と限定された範囲での脱重合

Biodegradation of low-density polyethylene and polystyrene in superworms, larvae of Zophobas atratus (Coleoptera: Tenebrionidae): Broad and limited extent depolymerization.
  • Bo-Yu Peng
  • Yiran Li
  • Rui Fan
  • Zhibin Chen
  • Jiabin Chen
  • Anja M Brandon
  • Craig S Criddle
  • Yalei Zhang
  • Wei-Min Wu
  • Environ. Pollut..2020 Jul;266(Pt 1):115206. S0269-7491(20)31299-9. doi: 10.1016/j.envpol.2020.115206.Epub 2020-07-10.

有望な薬剤候補としての2つの新しいクラスの融合アザイサイトシン含有コンジェナー。デザイン、合成、およびin vitro、ex vivo、in silico試験

Two novel classes of fused azaisocytosine-containing congeners as promising drug candidates: Design, synthesis as well as in vitro, ex vivo and in silico studies.
  • Małgorzata Sztanke
  • Jolanta Rzymowska
  • Małgorzata Janicka
  • Krzysztof Sztanke
  • Bioorg. Chem..2020 Jan;95:103480. S0045-2068(19)30556-5. doi: 10.1016/j.bioorg.2019.103480.Epub 2019-12-09.

実践におけるイノベーション。思春期の若者のための弁証法的行動療法：公共コミュニティのメンタルヘルス環境における16週間のプログラムの多施設実施と評価

Innovations in Practice: Dialectical behaviour therapy for adolescents: multisite implementation and evaluation of a 16-week programme in a public community mental health setting.
  • Daniel Flynn
  • Mary Kells
  • Mary Joyce
  • Paul Corcoran
  • Conall Gillespie
  • Catalina Suarez
  • Michaela Swales
  • Ella Arensman
  • Child Adolesc Ment Health.2019 Feb;24(1):76-83. doi: 10.1111/camh.12298.Epub 2018-09-17.

エナンチオピュアなスピロインドリン-3,5'-オキサゾリジン-2,2'-ジオンの合成のための触媒フリーの立体選択的なCOのフォーマル3+2-環化付加反応を水および環境下で開発した

Catalyst-Free Stereocontrolled Formal [3 + 2]-Cycloaddition of CO for the Synthesis of Enantiopure Spiro[indoline-3,5'-oxazolidine]-2,2'-diones under Aqueous and Ambient Conditions.
  • Saumen Hajra
  • Anurag Biswas
  • Org. Lett..2020 Jul;22(13):4990-4994. doi: 10.1021/acs.orglett.0c01526.Epub 2020-06-16.

コンパニオンアニマル用殺虫剤であるフララナーの、業界をリードする農業用殺虫剤と比較した、抵抗性および感受性のあるアブラバエの株に対する毒性

Toxicity of fluralaner, a companion animal insecticide, relative to industry-leading agricultural insecticides against resistant and susceptible strains of filth flies.
  • Edwin R Burgess
  • Christopher J Geden
  • Kimberly H Lohmeyer
  • B H King
  • Erika T Machtinger
  • Jeffrey G Scott
  • Sci Rep.2020 Jul;10(1):11166. 10.1038/s41598-020-68121-z. doi: 10.1038/s41598-020-68121-z.Epub 2020-07-07.

21-ヒドロキシラーゼ欠損症による非古典的先天性副腎肥大症の小児および青年における遺伝子型-フェノタイプ相関

Genotype-phenotype correlations in children and adolescents with nonclassical congenital adrenal hyperplasia due to 21-hydroxylase deficiency.
  • Helmuth-Günther Dörr
  • Nadja Schulze
  • Markus Bettendorf
  • Gerhard Binder
  • Walter Bonfig
  • Christian Denzer
  • Desiree Dunstheimer
  • Kirsten Salzgeber
  • Heinrich Schmidt
  • Karl Otfried Schwab
  • Egbert Voss
  • Martin Wabitsch
  • Joachim Wölfle
  • Mol Cell Pediatr.2020 Jul;7(1):8. 10.1186/s40348-020-00100-w. doi: 10.1186/s40348-020-00100-w.Epub 2020-07-09.

老化ニッチでのPiwiの減少は、Toll-GSK3シグナル伝達を介して生殖細胞幹細胞を排除する

Piwi reduction in the aged niche eliminates germline stem cells via Toll-GSK3 signaling.
  • Kun-Yang Lin
  • Wen-Der Wang
  • Chi-Hung Lin
  • Elham Rastegari
  • Yu-Han Su
  • Yu-Tzu Chang
  • Yung-Feng Liao
  • Yi-Chieh Chang
  • Haiwei Pi
  • Bo-Yi Yu
  • Shu-Hwa Chen
  • Chung-Yen Lin
  • Mei-Yeh Lu
  • Tsu-Yi Su
  • Fei-Yang Tzou
  • Chih-Chiang Chan
  • Hwei-Jan Hsu
  • Nat Commun.2020 Jun;11(1):3147. 10.1038/s41467-020-16858-6. doi: 10.1038/s41467-020-16858-6.Epub 2020-06-19.

SEPN1関連ミオパチーにおける小胞体とミトコンドリアの接触不良と生体エネルギー

Defective endoplasmic reticulum-mitochondria contacts and bioenergetics in SEPN1-related myopathy.
  • Anne Filipe
  • Alexander Chernorudskiy
  • Sandrine Arbogast
  • Ersilia Varone
  • Rocío-Nur Villar-Quiles
  • Diego Pozzer
  • Maryline Moulin
  • Stefano Fumagalli
  • Eva Cabet
  • Swati Dudhal
  • Maria-Grazia De Simoni
  • Raphaël Denis
  • Nathalie Vadrot
  • Corinne Dill
  • Matteo Giovarelli
  • Luke Szweda
  • Clara De Palma
  • Paolo Pinton
  • Carlotta Giorgi
  • Carlo Viscomi
  • Emilio Clementi
  • Sonia Missiroli
  • Simona Boncompagni
  • Ester Zito
  • Ana Ferreiro
  • Cell Death Differ..2020 Jul;10.1038/s41418-020-0587-z. doi: 10.1038/s41418-020-0587-z.Epub 2020-07-13.

定量的グローバル研究により、真菌王国全体での開始コドンコンテキストによる翻訳制御の違いが明らかになった

Quantitative global studies reveal differential translational control by start codon context across the fungal kingdom.
  • Edward W J Wallace
  • Corinne Maufrais
  • Jade Sales-Lee
  • Laura R Tuck
  • Luciana de Oliveira
  • Frank Feuerbach
  • Frédérique Moyrand
  • Prashanthi Natarajan
  • Hiten D Madhani
  • Guilhem Janbon
  • Nucleic Acids Res..2020 03;48(5):2312-2331. 5724440. doi: 10.1093/nar/gkaa060.

ホエイプロテインは、組織特異的な方法で重要な抗酸化酵素の活性を高めることで、ラットの抗酸化プロファイルを向上させます

Whey protein boosts the antioxidant profile of rats by enhancing the activities of crucial antioxidant enzymes in a tissue-specific manner.
  • Aristidis S Veskoukis
  • Efthalia Kerasioti
  • Zoi Skaperda
  • Porfirios Apostolos Papapostolou
  • Charitini Nepka
  • Demetrios A Spandidos
  • Eftihia Asprodini
  • Ioannis Taitzoglou
  • Demetrios Kouretas
  • Food Chem. Toxicol..2020 Aug;142:111508. S0278-6915(20)30398-7. doi: 10.1016/j.fct.2020.111508.Epub 2020-06-13.

妊娠中のシトルリンやアルギニンと母親のサプリメントは、子宮内成長制限（IUGR）のモデルで胎児のアミノ酸の可用性に影響を与えます

Maternal supplementation with citrulline or arginine during gestation impacts fetal amino acid availability in a model of intrauterine growth restriction (IUGR).
  • Aurélie Bourdon
  • Jacob Hannigsberg
  • Emilie Misbert
  • Thang Nhat Tran
  • Valérie Amarger
  • Véronique Ferchaud-Roucher
  • Norbert Winer
  • Dominique Darmaun
  • Clin Nutr.2020 Apr;S0261-5614(20)30154-0. doi: 10.1016/j.clnu.2020.03.036.Epub 2020-04-10.

フレイル高齢者における高血圧の管理-29 カ国の開業医によるガイドライン使用の役割

Managing hypertension in frail oldest-old-The role of guideline use by general practitioners from 29 countries.
  • Céline Roulet
  • Zsofia Rozsnyai
  • Katharina Tabea Jungo
  • Milly A van der Ploeg
  • Carmen Floriani
  • Donata Kurpas
  • Shlomo Vinker
  • Sanda Kreitmayer Pestic
  • Ferdinando Petrazzuoli
  • Kathryn Hoffmann
  • Rita P A Viegas
  • Christian Mallen
  • Athina Tatsioni
  • Hubert Maisonneuve
  • Claire Collins
  • Heidrun Lingner
  • Rosy Tsopra
  • Yolanda Mueller
  • Rosalinde K E Poortvliet
  • Jacobijn Gussekloo
  • Sven Streit
  • PLoS ONE.2020;15(7):e0236064. PONE-D-20-09925. doi: 10.1371/journal.pone.0236064.Epub 2020-07-10.

イングランド北西部の非粘膜性上皮性卵巣癌における生殖細胞型BRCA1/2検査の主流化

Mainstreaming germline BRCA1/2 testing in non-mucinous epithelial ovarian cancer in the North West of England.
  • Nicola Flaum
  • Robert D Morgan
  • George J Burghel
  • Michael Bulman
  • Andrew R Clamp
  • Jurjees Hasan
  • Claire L Mitchell
  • Doina Badea
  • Sarah Moon
  • Martin Hogg
  • Dennis Hadjiyiannakis
  • Tara Clancy
  • Helene Schlecht
  • Emma R Woodward
  • Emma J Crosbie
  • Richard J Edmondson
  • Andrew J Wallace
  • Gordon C Jayson
  • Fiona I Lalloo
  • Elaine F Harkness
  • D Gareth R Evans
  • Eur. J. Hum. Genet..2020 Jul;10.1038/s41431-020-0692-y. doi: 10.1038/s41431-020-0692-y.Epub 2020-07-10.

ホスホジエステラーゼ5A1とアバナフィルの複合体の構造から、イソフォーム選択性の分子基盤とハロゲン結合によるα-ヘリックス骨格酸素の標的化の指針を明らかにした

Structure of Human Phosphodiesterase 5A1 Complexed with Avanafil Reveals Molecular Basis of Isoform Selectivity and Guide-lines for Targeting α-Helix Backbone Oxygen by Halogen Bonding.
  • Chao-Ming Hsieh
  • Chun-Yi Chen
  • Ji-Wang Chern
  • Nei-Li Chan
  • J. Med. Chem..2020 Jul;doi: 10.1021/acs.jmedchem.0c00853.Epub 2020-07-14.

高脂肪食誘発性肥満とD-ガラクトース誘発性老化の動物モデルにおける海馬における脂肪量と肥満関連タンパク質発現の変化

Changes of fat-mass and obesity-associated protein expression in the hippocampus in animal models of high-fat diet-induced obesity and D-galactose-induced aging.
  • Min Soo Kang
  • Woosuk Kim
  • Tae Hyeong Kim
  • Hyo Young Jung
  • Hyun Jung Kwon
  • Dae Won Kim
  • In Koo Hwang
  • Jung Hoon Choi
  • Lab Anim Res.2020;36:20. 46. doi: 10.1186/s42826-020-00046-0.Epub 2020-07-06.

心臓埋め込み型電子機器を装着した患者に対する放射線治療

Radiotherapy in Patients With a Cardiac Implantable Electronic Device.
  • Ardalan Sharifzadehgan
  • Marc Laurans
  • Marine Thuillot
  • Andres Huertas
  • Pierre Baudinaud
  • Kumar Narayanan
  • Mariana Mirabel
  • Jean-Emmanuel Bibault
  • Pierre Frey
  • Victor Waldmann
  • Emilie Varlet
  • Denis Amet
  • Christophe Juin
  • Thomas Lavergne
  • Xavier Jouven
  • Philippe Giraud
  • Catherine Durdux
  • Eloi Marijon
  • Am. J. Cardiol..2020 Aug;128:196-201. S0002-9149(20)30467-7. doi: 10.1016/j.amjcard.2020.04.045.Epub 2020-05-15.

フェロモンオドラントレセプターの反応から、ヨーロッパのトウモロコシボローバー、Ostrinia nubilalisにおける秘密の冗長性フェロモン成分の存在が明らかになった

Pheromone Odorant Receptor Responses Reveal the Presence of a Cryptic, Redundant Sex Pheromone Component in the European Corn Borer, Ostrinia nubilalis.
  • Kevin W Wanner
  • Kevin Moore
  • Jianrong Wei
  • Brent C Herdlicka
  • Charles E Linn
  • Thomas C Baker
  • J. Chem. Ecol..2020 Jul;10.1007/s10886-020-01196-0. doi: 10.1007/s10886-020-01196-0.Epub 2020-07-17.

コートジボワールにおけるHIVに周産期感染した思春期の女性におけるヒト乳頭腫ウイルス感染症

Human papilloma viruses infection among adolescent females perinatally infected with HIV in Côte d'Ivoire.
  • Boris Tchounga
  • Apollinaire Horo
  • Simon Boni
  • Aristophane Tanon
  • Madeleine Amorissani Folquet
  • Isabelle Garrigue
  • Valeriane Leroy
  • François Dabis
  • Didier Ekouevi
  • Antoine Jaquet
  • Sex Transm Infect.2020 Jul;sextrans-2019-054420. doi: 10.1136/sextrans-2019-054420.Epub 2020-07-13.

フロリダ州の消防署における汚染防止対策の実施状況と消防組織レベルの特徴との関連。消防士がんイニシアチブからの証拠

Fire Service Organizational-level Characteristics are Associated with Adherence to Contamination Control Practices in Florida Fire Departments: Evidence from the Firefighter Cancer Initiative.
  • Paola Louzado-Feliciano
  • Kevin A Griffin
  • Katerina M Santiago
  • Natasha Schaefer Solle
  • Tulay Koru-Sengul
  • Casey Grant
  • Neal Niemczyk
  • David J Lee
  • Erin N Kobetz
  • Alberto J Caban-Martinez
  • J. Occup. Environ. Med..2020 Jul;doi: 10.1097/JOM.0000000000001953.Epub 2020-07-07.

α-トコフェロールベースのPEG化リポソームを用いたmicroRNA-134（miR-134）の外因性送達による皮膚扁平上皮癌の効果的な治療法

Exogenous delivery of microRNA-134 (miR-134) using α-tocopherol-based PEGylated liposome for effective treatment in skin squamous cell carcinoma.
  • Chen Jing
  • Li Yan
  • Zhang Wei
  • Zhang Shoumin
  • Yin Guangwen
  • Zhang Jiangan
  • Jia Xuesong
  • Chen Hongxiang
  • Duan Ziyu
  • Li Jianguo
  • Drug Deliv Transl Res.2020 Jun;10.1007/s13346-020-00811-7. doi: 10.1007/s13346-020-00811-7.Epub 2020-06-22.

LncRNAであるFTXは、Kupffer細胞のM1/M2分極を制御することで、非アルコール性脂肪肝疾患から肝細胞癌への進行を抑制することが明らかになった

LncRNA FTX represses the progression of non-alcoholic fatty liver disease to hepatocellular carcinoma via regulating the M1/M2 polarization of Kupffer cells.
  • Huajun Wu
  • Zhiwei Zhong
  • Anji Wang
  • Chunhui Yuan
  • Ke Ning
  • Huanhuan Hu
  • Chao Wang
  • Xiangbao Yin
  • Cancer Cell Int..2020;20:266. 1354. doi: 10.1186/s12935-020-01354-0.Epub 2020-06-24.

プレオトロピンは血管内皮増殖因子受容体2に選択的に結合し、αβインテグリンの発現に依存して細胞移動を阻害または刺激する

Pleiotrophin selectively binds to vascular endothelial growth factor receptor 2 and inhibits or stimulates cell migration depending on αβ integrin expression.
  • Margarita Lamprou
  • Pinelopi Kastana
  • Fani Kofina
  • Ηaralampos Tzoupis
  • Spyridoula Barmpoutsi
  • Md Sanaullah Sajib
  • Marina Koutsioumpa
  • Evangelia Poimenidi
  • Aikaterini A Zompra
  • Dimitrios Tassopoulos
  • Effrosyni Choleva
  • Theodore Tselios
  • Constantinos M Mikelis
  • Evangelia Papadimitriou
  • Angiogenesis.2020 Jul;10.1007/s10456-020-09733-x. doi: 10.1007/s10456-020-09733-x.Epub 2020-07-17.

アヤワスカがナイーブユーザーのメンタルヘルスと生活の質に与える影響。縦断的研究と横断的研究の組み合わせ

Effects of ayahuasca on mental health and quality of life in naïve users: A longitudinal and cross-sectional study combination.
  • Daniel F Jiménez-Garrido
  • María Gómez-Sousa
  • Genís Ona
  • Rafael G Dos Santos
  • Jaime E C Hallak
  • Miguel Ángel Alcázar-Córcoles
  • José Carlos Bouso
  • Sci Rep.2020 Mar;10(1):4075. 10.1038/s41598-020-61169-x. doi: 10.1038/s41598-020-61169-x.Epub 2020-03-05.

酵母細胞壁由来のマンノプロテインの活性画分は、成犬および高齢犬の自然免疫および獲得免疫を刺激する

Active fractions of mannoproteins derived from yeast cell wall stimulate innate and acquired immunity of adult and elderly dogs.
  • F S A Kroll
  • T C Putarov
  • L Zaine
  • K S Venturini
  • C G Aoki
  • J P F Santos
  • V Pedrinelli
  • T H A Vendramini
  • M A Brunetto
  • A C Carciofi
  • Anim. Feed Sci. Technol..2020 Mar;261:114392. S0377-8401(18)31570-0. doi: 10.1016/j.anifeedsci.2020.114392.Epub 2020-01-10.

海洋南極のエコロジー氷河における氷晶石穴生態系のビオトープとバイオセノシス

Biotope and biocenosis of cryoconite hole ecosystems on Ecology Glacier in the maritime Antarctic.
  • Jakub Buda
  • Edyta Łokas
  • Mirosława Pietryka
  • Dorota Richter
  • Wojciech Magowski
  • Nataliia S Iakovenko
  • Dorota L Porazinska
  • Tomasz Budzik
  • Mariusz Grabiec
  • Jakub Grzesiak
  • Piotr Klimaszyk
  • Paweł Gaca
  • Krzysztof Zawierucha
  • Sci. Total Environ..2020 Jul;724:138112. S0048-9697(20)31625-9. doi: 10.1016/j.scitotenv.2020.138112.Epub 2020-03-24.

スプライシングとマイクロプロセッサー複合体の拮抗は、細胞周期再突入のためのLnc-MIRHGの血清誘発処理を決定する

Antagonism between Splicing and Microprocessor complex Dictates the Serum-induced Processing of Lnc-MIRHG for Efficient Cell Cycle Re-entry.
  • Qinyu Sun
  • Qinyu Hao
  • Yo-Chuen Lin
  • You Jin Song
  • Sushant Bangru
  • Waqar Arif
  • Vidisha Tripathi
  • Yang Zhang
  • Jung-Hyun Cho
  • Susan M Freier
  • Lisa Jenkins
  • Jian Ma
  • Je-Hyun Yoon
  • Auinash Kalsotra
  • Ashish Lal
  • Supriya G Prasanth
  • Kannanganattu V Prasanth
  • RNA.2020 Jul;rna.075309.120. doi: 10.1261/rna.075309.120.Epub 2020-07-16.

カーボベルデにおける2015-2016年のジカウイルスアウトブレイクのゲノム疫学

Genomic Epidemiology of 2015-2016 Zika Virus Outbreak in Cape Verde.
  • Oumar Faye
  • Maria de Lourdes Monteiro
  • Bram Vrancken
  • Matthieu Prot
  • Sebastian Lequime
  • Maryam Diarra
  • Oumar Ndiaye
  • Tomas Valdez
  • Sandra Tavarez
  • Jessica Ramos
  • Silvânia da Veiga Leal
  • Cecilio Pires
  • Antonio Moreira
  • Maria Filomena Tavares
  • Linete Fernandes
  • Jorge Noel Barreto
  • Maria do Céu Teixeira
  • Maria da Luz de Lima Mendonça
  • Carolina Cardoso da Silva Leite Gomes
  • Mariano Salazar Castellon
  • Laurence Ma
  • Frédéric Lemoine
  • Fabiana Gámbaro-Roglia
  • Déborah Delaune
  • Gamou Fall
  • Ibrahima Socé Fall
  • Mamadou Diop
  • Anavaj Sakuntabhai
  • Cheikh Loucoubar
  • Philippe Lemey
  • Edward C Holmes
  • Ousmane Faye
  • Amadou Alpha Sall
  • Etienne Simon-Loriere
  • Emerging Infect. Dis..2020 Jun;26(6):1084-1090. doi: 10.3201/eid2606.190928.

エクスパンシン遺伝子ファミリーのゲノムワイドな同定により、エクスパンシン遺伝子が綿花の繊維細胞の成長に関与していることが明らかになった

Genome-wide identification of the expansin gene family reveals that expansin genes are involved in fibre cell growth in cotton.
  • Li-Min Lv
  • Dong-Yun Zuo
  • Xing-Fen Wang
  • Hai-Liang Cheng
  • You-Ping Zhang
  • Qiao-Lian Wang
  • Guo-Li Song
  • Zhi-Ying Ma
  • BMC Plant Biol..2020 May;20(1):223. 10.1186/s12870-020-02362-y. doi: 10.1186/s12870-020-02362-y.Epub 2020-05-19.

微粒子状物質曝露と乳房腫瘍および隣接正常乳房組織における遺伝子発現経路との関与

Involvement of fine particulate matter exposure with gene expression pathways in breast tumor and adjacent-normal breast tissue.
  • Natalie C DuPré
  • Yujing J Heng
  • Benjamin A Raby
  • Kimberly Glass
  • Jaime E Hart
  • Jen-Hwa Chu
  • Catherine Askew
  • A Heather Eliassen
  • Susan E Hankinson
  • Peter Kraft
  • Francine Laden
  • Rulla M Tamimi
  • Environ. Res..2020 Jul;186:109535. S0013-9351(20)30428-X. doi: 10.1016/j.envres.2020.109535.Epub 2020-04-15.

ショウジョウバエメラノガスターの性ペプチドの構造：水酸化イソロイシンの同定とアミノ酸の水酸化パターンの系統変化

The structure of the Drosophila melanogaster sex peptide: Identification of hydroxylated isoleucine and a strain variation in the pattern of amino acid hydroxylation.
  • Sebastian Sturm
  • Adam Dowle
  • Neil Audsley
  • R Elwyn Isaac
  • Insect Biochem. Mol. Biol..2020 Jun;124:103414. S0965-1748(20)30103-X. doi: 10.1016/j.ibmb.2020.103414.Epub 2020-06-24.

危機的に絶滅の危機に瀕している単一島嶼の固有種の鳥では、高いMHC遺伝子コピー数がホモ接合にもかかわらず多様性を維持しているが、MHCに基づく仲間選択の証拠はない

High MHC gene copy number maintains diversity despite homozygosity in a Critically Endangered single-island endemic bird, but no evidence of MHC-based mate choice.
  • Martin Stervander
  • Elisa G Dierickx
  • Jack Thorley
  • M de L Brooke
  • Helena Westerdahl
  • Mol. Ecol..2020 May;doi: 10.1111/mec.15471.Epub 2020-05-16.

肺サルコイドーシスにおける高用量ブデゾニド吸入開始後の臨床経過と血清KL-6レベルの顕著な改善

Remarkable Improvement in Clinical Course and Serum KL-6 Levels after Initiation of High-Dose Inhaled Budesonide in Pulmonary Sarcoidosis.
  • Yoshitaka Morimatsu
  • Masaki Okamoto
  • Tomotaka Kawayama
  • Yusuke Mizoguchi
  • Haruki Imaoka
  • Hideo Ogino
  • Taketoshi Kawazu
  • Tatsuya Ishitake
  • Tomoaki Hoshino
  • Kurume Med J.2020 Jul;66(1):71-75. doi: 10.2739/kurumemedj.MS661003.Epub 2020-05-01.

糖尿病性肩関節炎患者における肩の痛み、機能、可動域の改善における橈骨体外衝撃波治療と超音波ガイド下低用量関節内ステロイド注射の有効性

Effectiveness of radial extracorporeal shock-wave therapy versus ultrasound-guided low-dose intra-articular steroid injection in improving shoulder pain, function, and range of motion in diabetic patients with shoulder adhesive capsulitis.
  • Tasneem El Desouky Mohammed El Naggar
  • Ahmed Ibrahim Elsayed Maaty
  • Aly Elsayed Mohamed
  • J Shoulder Elbow Surg.2020 Jul;29(7):1300-1309. S1058-2746(20)30265-2. doi: 10.1016/j.jse.2020.03.005.

妊婦の血糖コントロールマーカーと母体および新生児の転帰との関係に関する多施設共同全包括的プロスペクティブ研究

A multicenter all-inclusive prospective study on the relationship between glycemic control markers and maternal and neonatal outcomes in pregnant women.
  • Xiaoming Zhang
  • Yumei Wei
  • Ling Fan
  • Yangyu Zhao
  • Yufeng Li
  • Yanjun Liu
  • Juming Lu
  • Linong Ji
  • Huixia Yang
  • J. Matern. Fetal. Neonatal. Med..2020 Jul;:1-8. doi: 10.1080/14767058.2019.1678139.Epub 2020-07-15.

ヒト感染性マラリア寄生虫におけるRH5複合体構成要素CyRPAとRIPRの多様な役割

Divergent roles for the RH5 complex components, CyRPA and RIPR in human-infective malaria parasites.
  • Ellen Knuepfer
  • Katherine E Wright
  • Surendra Kumar Prajapati
  • Thomas A Rawlinson
  • Franziska Mohring
  • Marion Koch
  • Oliver R Lyth
  • Steven A Howell
  • Elizabeth Villasis
  • Ambrosius P Snijders
  • Robert W Moon
  • Simon J Draper
  • Anna Rosanas-Urgell
  • Matthew K Higgins
  • Jake Baum
  • Anthony A Holder
  • PLoS Pathog..2019 06;15(6):e1007809. PPATHOGENS-D-18-01406. doi: 10.1371/journal.ppat.1007809.Epub 2019-06-11.

2 型糖尿病または原発性高コレステロール血症患者における高オンアスピリン血小板反応性とスーパーオキシドジスムターゼ活性低下との関連

Association between High On-Aspirin Platelet Reactivity and Reduced Superoxide Dismutase Activity in Patients Affected by Type 2 Diabetes Mellitus or Primary Hypercholesterolemia.
  • Cristina Barale
  • Franco Cavalot
  • Chiara Frascaroli
  • Katia Bonomo
  • Alessandro Morotti
  • Angelo Guerrasio
  • Isabella Russo
  • Int J Mol Sci.2020 Jul;21(14). E4983. doi: 10.3390/ijms21144983.Epub 2020-07-15.

水性媒体からビスフェノールA（BPA）を除去するためのスイッチグラス（Panicum virgatum）（米国産2品種）のファイトレメディエーションの可能性

Phytoremediation potential of switchgrass (Panicum virgatum), two United States native varieties, to remove bisphenol-A (BPA) from aqueous media.
  • Jacob C Phouthavong-Murphy
  • Alyssa K Merrill
  • Stephanie Zamule
  • David Giacherio
  • Beverly Brown
  • Carol Roote
  • Padmini Das
  • Sci Rep.2020 01;10(1):835. 10.1038/s41598-019-56655-w. doi: 10.1038/s41598-019-56655-w.Epub 2020-01-21.

思春期の鎖骨骨折の記述的疫学。FACTS（思春期鎖骨外傷および手術後の機能）プロスペクティブ多施設コホート研究の結果

Descriptive Epidemiology of Adolescent Clavicle Fractures: Results From the FACTS (Function after Adolescent Clavicle Trauma and Surgery) Prospective, Multicenter Cohort Study.
  • Henry B Ellis
  • Ying Li
  • Donald S Bae
  • Leslie A Kalish
  • Philip L Wilson
  • Andrew T Pennock
  • Jeffrey J Nepple
  • Samuel C Willimon
  • David D Spence
  • Nirav K Pandya
  • Mininder S Kocher
  • Eric W Edmonds
  • Frances A Farley
  • J Eric Gordon
  • Derek M Kelly
  • Michael T Busch
  • Coleen S Sabatini
  • Benton E Heyworth
  • Orthop J Sports Med.2020 May;8(5):2325967120921344. 10.1177_2325967120921344. doi: 10.1177/2325967120921344.Epub 2020-05-29.

ClbR は大腸菌におけるコリバクチン遺伝子発現の鍵となる転写活性化因子である

ClbR Is the Key Transcriptional Activator of Colibactin Gene Expression in Escherichia coli.
  • Alexander Wallenstein
  • Nadine Rehm
  • Marina Brinkmann
  • Martina Selle
  • Nadège Bossuet-Greif
  • Daniel Sauer
  • Boyke Bunk
  • Cathrin Spröer
  • Haleluya Tesfaye Wami
  • Stefan Homburg
  • Rudolf von Bünau
  • Simone König
  • Jean-Philippe Nougayrède
  • Jörg Overmann
  • Eric Oswald
  • Rolf Müller
  • Ulrich Dobrindt
  • mSphere.2020 Jul;5(4). e00591-20. doi: 10.1128/mSphere.00591-20.Epub 2020-07-15.

イタリアにおけるロンゴバルド人の移動性の指標としてのストロンチウムと酸素同位体：ポベグリーノ・ヴェロネーゼでの調査

Strontium and oxygen isotopes as indicators of Longobards mobility in Italy: an investigation at Povegliano Veronese.
  • Guendalina Francisci
  • Ileana Micarelli
  • Paola Iacumin
  • Francesca Castorina
  • Fabio Di Vincenzo
  • Martina Di Matteo
  • Caterina Giostra
  • Giorgio Manzi
  • Mary Anne Tafuri
  • Sci Rep.2020 Jul;10(1):11678. 10.1038/s41598-020-67480-x. doi: 10.1038/s41598-020-67480-x.Epub 2020-07-15.

LPAR2受容体の活性化は、マウス大腸における放射線誘発性のアピカルジャンクショナルコンプレックスの破壊と粘膜バリア機能障害を減衰させる

LPAR2 receptor activation attenuates radiation-induced disruption of apical junctional complexes and mucosal barrier dysfunction in mouse colon.
  • Pradeep K Shukla
  • Avtar S Meena
  • Ruchika Gangwar
  • Erzsebet Szabo
  • Andrea Balogh
  • Sue Chin Lee
  • Alain Vandewalle
  • Gabor Tigyi
  • RadhaKrishna Rao
  • FASEB J..2020 Jul;doi: 10.1096/fj.202000544R.Epub 2020-07-12.

ミクロンおよびサブミクロンサイズのコアシェルキャリアのラジオラベリング戦略を研究する

Radiolabeling Strategies of Micron- and Submicron-Sized Core-Shell Carriers for Studies.
  • Mikhail V Zyuzin
  • Dmitrii Antuganov
  • Yana V Tarakanchikova
  • Timofey E Karpov
  • Tatiana V Mashel
  • Elena N Gerasimova
  • Oleksii O Peltek
  • Nominé Alexandre
  • Stéphanie Bruyere
  • Yulia A Kondratenko
  • Albert R Muslimov
  • Alexander S Timin
  • ACS Appl Mater Interfaces.2020 Jul;12(28):31137-31147. doi: 10.1021/acsami.0c06996.Epub 2020-07-02.

第二世代クリオバルーンアブレーション後の心房不整脈再発のメカニズムを検討した

The mechanisms of recurrent atrial arrhythmias after second-generation cryoballoon ablation.
  • Shinsuke Miyazaki
  • Tomoki Horie
  • Hitoshi Hachiya
  • Kanae Hasegawa
  • Takatsugu Kajiyama
  • Tomonori Watanabe
  • Hiroaki Nakamura
  • Eri Ishikawa
  • Moe Mukai
  • Daisetsu Aoyama
  • Minoru Nodera
  • Kenichi Kaseno
  • Yoshito Iesaka
  • Hiroshi Tada
  • Am. Heart J..2020 03;221:29-38. S0002-8703(19)30342-4. doi: 10.1016/j.ahj.2019.12.002.Epub 2019-12-16.

ナノスケールのクルクミンとレスベラトロールの、変調された電気ハイパーサーミアによる大腸がんにおける宿主免疫と抗腫瘍効果の潜在的な強化

Potential enhancement of host immunity and anti-tumor efficacy of nanoscale curcumin and resveratrol in colorectal cancers by modulated electro- hyperthermia.
  • I-Ming Kuo
  • Jih-Jong Lee
  • Yu-Shan Wang
  • Hsin-Chien Chiang
  • Cheng-Chung Huang
  • Pei-Jong Hsieh
  • Winston Han
  • Chiao-Hsu Ke
  • Albert T C Liao
  • Chen-Si Lin
  • BMC Cancer.2020 Jun;20(1):603. 10.1186/s12885-020-07072-0. doi: 10.1186/s12885-020-07072-0.Epub 2020-06-29.

黒リンナノシートを用いた花のような3次元MOFのMnドーピングによる階層的な花弁成長を利用したヒトストレス誘導性ホスホタンパク質1の電気化学的アプタセンサの開発

Mn-Doping-induced hierarchical petal growth of a flower-like 3D MOF assembled with black phosphorous nanosheets as an electrochemical aptasensor of human stress-induced phosphoprotein 1.
  • Zejun Sun
  • Hui Jin
  • Yujiao Sun
  • Xiaowen Jiang
  • Rijun Gui
  • Nanoscale.2020 Jul;12(27):14538-14548. doi: 10.1039/d0nr02342f.Epub 2020-07-02.

治癒療法が適応とならない小型（5cm以下）肝細胞がんに対する定位放射線療法。単群、第II相臨床試験の結果

Stereotactic body radiation therapy for small (≤5 cm) hepatocellular carcinoma not amenable to curative treatment: Results of a single-arm, phase II clinical trial.
  • Sang Min Yoon
  • So Yeon Kim
  • Young-Suk Lim
  • Kang Mo Kim
  • Ju Hyun Shim
  • Danbi Lee
  • Jihyun An
  • Jinhong Jung
  • Jong Hoon Kim
  • Han Chu Lee
  • Clin Mol Hepatol.2020 Jul;cmh.2020.0038. doi: 10.3350/cmh.2020.0038.Epub 2020-07-10.

リドカイン、ロピバカイン、ブピバカインのヒト脂肪由来間葉系幹細胞の生存率および代謝活性に対する細胞毒性の違い

Differences in cytotoxicity of lidocaine, ropivacaine, bupivacaine on the viability and metabolic activity of human adipose-derived mesenchymal stem cells.
  • Eva Kubrova
  • Min Su
  • Catalina Galeano-Garces
  • M Lizeth Galvan
  • Sofia Jerez
  • Allan B Dietz
  • Jay Smith
  • Wenchun Qu
  • Andre J van Wijnen
  • Am J Phys Med Rehabil.2020 Jul;doi: 10.1097/PHM.0000000000001529.Epub 2020-07-09.

2種類のレニン-アンジオテンシン系阻害薬のラットにおけるβ因子XIIaに関連したニュープレッサー蛋白質によって誘導される高血圧に対する効果

The effects of two types of renin-angiotensin system inhibitors on the hypertension induced by new pressor protein associated with beta-factor XIIa in rats.
  • Akbar Pejhan
  • Ali Gohari
  • Mohammad Hassan Rakhshani
  • Peter C Papageorgiou
  • Muhammad Ibrar Mustafa
  • Rahim Golmohammadi
  • Res Pharm Sci.2020 Apr;15(2):174-181. RPS-15-174. doi: 10.4103/1735-5362.283817.Epub 2020-05-11.

臼歯部切歯低小石灰化の影響を受けた切歯に対するカゼインホスホペプチドアモルファスリン酸カルシウムによるマイクロアブレーションおよびマイクロアブレーション後の審美性の比較評価

Comparative Evaluation of Esthetics after Microabrasion and Microabrasion followed by Casein Phosphopeptide-Amorphous Calcium Fluoride Phosphate on Molar Incisor Hypomineralization-Affected Incisors.
  • Ranu Bhandari
  • Seema Thakur
  • Parul Singhal
  • Deepak Chauhan
  • Cheranjeevi Jayam
  • Teerthesh Jain
  • Contemp Clin Dent.2019 Jan-Mar;10(1):9-15. CCD-10-9. doi: 10.4103/ccd.ccd_852_17.

心房細動および／またはフラッターを有する患者における、除細動時またはアブレーション時の抑うつ症状と不安の探索

Exploring Depressive Symptoms and Anxiety Among Patients With Atrial Fibrillation and/or Flutter at the Time of Cardioversion or Ablation.
  • Theresa A Koleck
  • Shazia A Mitha
  • Angelo Biviano
  • Billy A Caceres
  • Elizabeth J Corwin
  • Isaac Goldenthal
  • Ruth Masterson Creber
  • Meghan Reading Turchioe
  • Kathleen T Hickey
  • Suzanne Bakken
  • J Cardiovasc Nurs.2020 Jul;doi: 10.1097/JCN.0000000000000723.Epub 2020-07-13.

イングランド、スコットランドとノルウェー、スウェーデンとの歯科および口腔感染症に対する抗菌薬処方の比較と、2010年から2016年までの全国消費に対する相対的な貢献

Comparison of antimicrobial prescribing for dental and oral infections in England and Scotland with Norway and Sweden and their relative contribution to national consumption 2010-2016.
  • Andrew Smith
  • Rania Al-Mahdi
  • William Malcolm
  • Nikolaus Palmer
  • Gunnar Dahlen
  • Mohammed Al-Haroni
  • BMC Oral Health.2020 Jun;20(1):172. 10.1186/s12903-020-01163-x. doi: 10.1186/s12903-020-01163-x.Epub 2020-06-16.

S1ドメインRNA結合タンパク質（CvfD）は、D39における寒冷感受性、リン酸輸送、および病原性を媒介する新しい転写後調節因子である

S1-Domain RNA-Binding Protein (CvfD) Is a New Post-Transcriptional Regulator That Mediates Cold Sensitivity, Phosphate Transport, and Virulence in D39.
  • Dhriti Sinha
  • Jiaqi J Zheng
  • Ho-Ching Tiffany Tsui
  • John D Richardson
  • Nicholas R De Lay
  • Malcolm E Winkler
  • J. Bacteriol..2020 Jun;JB.00245-20. doi: 10.1128/JB.00245-20.Epub 2020-06-29.

小児肥満に対する包括的介入が低年齢児の食生活の多様性に及ぼす影響。中国における学校ベースの無作為化比較試験からのエビデンス

The effect of comprehensive intervention for childhood obesity on dietary diversity among younger children: Evidence from a school-based randomized controlled trial in China.
  • Haiquan Xu
  • Olivier Ecker
  • Qian Zhang
  • Songming Du
  • Ailing Liu
  • Yanping Li
  • Xiaoqi Hu
  • Tingyu Li
  • Hongwei Guo
  • Ying Li
  • Guifa Xu
  • Weijia Liu
  • Jun Ma
  • Junmao Sun
  • Kevin Chen
  • Guansheng Ma
  • PLoS ONE.2020;15(7):e0235951. PONE-D-19-24892. doi: 10.1371/journal.pone.0235951.Epub 2020-07-17.

食事誘発性肥満モデルにおけるクロピドグレル抵抗性はインターロイキン-1受容体によって媒介され、DT-678で克服される

Clopidogrel Resistance in a Murine Model of Diet-Induced Obesity Is Mediated by the Interleukin-1 Receptor and Overcome With DT-678.
  • Yifang Sun
  • Jessica Venugopal
  • Chiao Guo
  • Yanbo Fan
  • Jianping Li
  • Yanjun Gong
  • Y Eugene Chen
  • Haoming Zhang
  • Daniel T Eitzman
  • Arterioscler. Thromb. Vasc. Biol..2020 06;40(6):1533-1542. doi: 10.1161/ATVBAHA.120.314146.Epub 2020-04-09.

デンマークにおける同種造血幹細胞移植後の慢性眼球移植片対宿主病-条件付けレジメンに応じた成人のリスクと発生率に関連する因子

Chronic ocular graft-versus-host disease after allogeneic haematopoietic stem cell transplantation in Denmark - factors associated with risks and rates in adults according to conditioning regimen.
  • Helene Jeppesen
  • Henrik Sengeløv
  • Frank Eriksson
  • Jens Folke Kiilgaard
  • Susanne Tvede Andersen
  • Jens Lindegaard
  • Hanne Olsen Julian
  • Steffen Heegaard
  • Bone Marrow Transplant..2020 Jul;10.1038/s41409-020-0993-3. doi: 10.1038/s41409-020-0993-3.Epub 2020-07-12.

CBCTを用いた無外傷性副鼻腔補強術のコンピュータベースの定量化

Computer-based quantification of an atraumatic sinus augmentation technique using CBCT.
  • F Inchingolo
  • G Dipalma
  • G Paduanelli
  • L A De Oliveira
  • A M Inchingolo
  • P I Georgakopoulos
  • A D Inchingolo
  • G Malcangi
  • E Athanasiou
  • E Fotopoulou
  • S Tsantis
  • I P Georgakopoulos
  • N C Diem Kieu
  • C Gargiulo Isacco
  • A Ballini
  • F Goker
  • C Mortellaro
  • A Greco Lucchina
  • M Del Fabbro
  • J. Biol. Regul. Homeost. Agents.2019 Nov-Dec;33(6 Suppl. 2):31-39. 4.

MAPTハプロタイプ層別化GWASにより、ADリスクバリアントの差動関連が明らかになった

MAPT haplotype-stratified GWAS reveals differential association for AD risk variants.
  • Samantha L Strickland
  • Joseph S Reddy
  • Mariet Allen
  • Aurelie N'songo
  • Jeremy D Burgess
  • Morgane M Corda
  • Travis Ballard
  • Xue Wang
  • Minerva M Carrasquillo
  • Joanna M Biernacka
  • Gregory D Jenkins
  • Shubhabrata Mukherjee
  • Kevin Boehme
  • Paul Crane
  • John S Kauwe
  • Nilüfer Ertekin-Taner
  • Alzheimers Dement.2020 Jul;16(7):983-1002. doi: 10.1002/alz.12099.Epub 2020-05-13.

Erratum to '10-year Mortality, Disease Progression, and Treatment-related Side Effects in the Men with Localised Prostate Cancer from ProtecT Randomised Controlled Trial According to the Treatment Received' European Urology 77 (2020) 320-330

Erratum to 'Ten-year Mortality, Disease Progression, and Treatment-related Side Effects in Men with Localised Prostate Cancer from the ProtecT Randomised Controlled Trial According to Treatment Received' [European Urology 77 (2020) 320-330].
  • David E Neal
  • Chris Metcalfe
  • Jenny L Donovan
  • J Athene Lane
  • Michael Davis
  • Grace J Young
  • Susan J Dutton
  • Eleanor I Walsh
  • Richard M Martin
  • Tim J Peters
  • Emma L Turner
  • Malcolm Mason
  • Richard Bryant
  • Prasad Bollina
  • James Catto
  • Alan Doherty
  • David Gillatt
  • Vincent Gnanapragasam
  • Peter Holding
  • Owen Hughes
  • Roger Kockelbergh
  • Howard Kynaston
  • Jon Oxley
  • Alan Paul
  • Edgar Paez
  • Derek J Rosario
  • Edward Rowe
  • John Staffurth
  • Doug G Altman
  • Freddie C Hamdy
  • Eur. Urol..2020 Jul;S0302-2838(20)30392-4. doi: 10.1016/j.eururo.2020.05.030.Epub 2020-07-02.

ヒト細胞におけるコンビナトリアル遺伝学的スクリーニングのためのAsCas12aの最適化

Optimization of AsCas12a for combinatorial genetic screens in human cells.
  • Peter C DeWeirdt
  • Kendall R Sanson
  • Annabel K Sangree
  • Mudra Hegde
  • Ruth E Hanna
  • Marissa N Feeley
  • Audrey L Griffith
  • Teng Teng
  • Samantha M Borys
  • Christine Strand
  • J Keith Joung
  • Benjamin P Kleinstiver
  • Xuewen Pan
  • Alan Huang
  • John G Doench
  • Nat. Biotechnol..2020 Jul;10.1038/s41587-020-0600-6. doi: 10.1038/s41587-020-0600-6.Epub 2020-07-13.

不確定な腎腫瘤に対する造影超音波検査が患者の臨床管理に及ぼす影響。2施設からのレトロスペクティブな分析。2施設からのレトロスペクティブ分析

Effects of Contrast-Enhanced Ultrasound of Indeterminate Renal Masses on Patient Clinical Management: Retrospective Analysis from Two Institutions: Retrospective Analysis From 2 Institutions.
  • John R Eisenbrey
  • Aya Kamaya
  • Sriharsha Gummadi
  • Kristen Bird
  • David Burrowes
  • Diego Arias
  • Costas D Lallas
  • Edouard J Trabulsi
  • Andrej Lyshchik
  • J Ultrasound Med.2020 Jul;doi: 10.1002/jum.15383.Epub 2020-07-13.

ブタ精子を17℃で液体保存している間の精液中の血漿の存在は、精子の体外容量化とアクロソームエクソサイトーシスを誘発する能力を調節している

The Presence of Seminal Plasma during Liquid Storage of Pig Spermatozoa at 17 °C Modulates Their Ability to Elicit In Vitro Capacitation and Trigger Acrosomal Exocytosis.
  • Ana Paula Pinoti Pavaneli
  • Sandra Recuero
  • Bruna Resende Chaves
  • Estela Garcia-Bonavila
  • Marc Llavanera
  • Elisabeth Pinart
  • Sergi Bonet
  • André Furugen Cesar De Andrade
  • Marc Yeste
  • Int J Mol Sci.2020 Jun;21(12). E4520. doi: 10.3390/ijms21124520.Epub 2020-06-25.

抗レトロウイルス療法にもかかわらず、潜在的な病原性細菌を有するHIV感染者における気道マイクロバイオームの富化

Enrichment of the airway microbiome in people living with HIV with potential pathogenic bacteria despite antiretroviral therapy.
  • Sylvia A D Rofael
  • James Brown
  • Elisha Pickett
  • Margaret Johnson
  • John R Hurst
  • David Spratt
  • Marc Lipman
  • Timothy D McHugh
  • EClinicalMedicine.2020 Jul;24:100427. S2589-5370(20)30171-1. doi: 10.1016/j.eclinm.2020.100427.Epub 2020-06-27.

ヒト髄芽細胞腫細胞における短期ヘッジホッグシグナル伝達のリン酸化プロテオミクス

Phosphoproteomics of short-term hedgehog signaling in human medulloblastoma cells.
  • Tamara Scheidt
  • Oliver Alka
  • Humberto Gonczarowska-Jorge
  • Wolfgang Gruber
  • Florian Rathje
  • Margherita Dell'Aica
  • Marc Rurik
  • Oliver Kohlbacher
  • René P Zahedi
  • Fritz Aberger
  • Christian G Huber
  • Cell Commun. Signal.2020 Jun;18(1):99. 10.1186/s12964-020-00591-0. doi: 10.1186/s12964-020-00591-0.Epub 2020-06-23.

気候温暖化に伴う範囲拡大と在来植物の環境下における土壌線虫群集の緯度的変化

Latitudinal variation in soil nematode communities under climate warming-related range-expanding and native plants.
  • Rutger A Wilschut
  • Stefan Geisen
  • Henk Martens
  • Olga Kostenko
  • Mattias de Hollander
  • Freddy C Ten Hooven
  • Carolin Weser
  • L Basten Snoek
  • Janneke Bloem
  • Danka Caković
  • Tatjana Čelik
  • Kadri Koorem
  • Nikos Krigas
  • Marta Manrubia
  • Kelly S Ramirez
  • Maria A Tsiafouli
  • Branko Vreš
  • Wim H van der Putten
  • Glob Chang Biol.2019 08;25(8):2714-2726. doi: 10.1111/gcb.14657.Epub 2019-05-20.

術前に目立たない腎機能を有する患者における腎部分切除術後の慢性腎臓病-好奇心か、それとも関連する問題か？

Chronic Kidney Disease After Partial Nephrectomy in Patients With Preoperative Inconspicuous Renal Function - Curiosity or Relevant Issue?
  • Malin Nientiedt
  • Riccardo Bertolo
  • Riccardo Campi
  • Umberto Capitanio
  • Selcuk Erdem
  • Önder Kara
  • Tobias Klatte
  • Alessandro Larcher
  • Maria Carmen Mir
  • Idir Ouzaid
  • Eduard Roussel
  • Maciej Salagierski
  • Frank Waldbillig
  • Maximillian Christian Kriegmair
  • Clin Genitourin Cancer.2020 May;S1558-7673(20)30115-4. doi: 10.1016/j.clgc.2020.05.007.Epub 2020-05-20.

HDAC1/2 阻害剤ロミデプシンがマウスの DEN 誘発肝細胞発癌を抑制することを明らかにした

HDAC1/2 Inhibitor Romidepsin Suppresses DEN-Induced Hepatocellular Carcinogenesis in Mice.
  • Hara Afaloniati
  • Katerina Angelopoulou
  • Alexander Giakoustidis
  • Alexandros Hardas
  • Athanasios Pseftogas
  • Kali Makedou
  • Athanasios Gargavanis
  • Thomas Goulopoulos
  • Stavros Iliadis
  • Vasileios Papadopoulos
  • Apostolos Papalois
  • George Mosialos
  • Theofilos Poutahidis
  • Dimitrios Giakoustidis
  • Onco Targets Ther.2020;13:5575-5588. 250233. doi: 10.2147/OTT.S250233.Epub 2020-06-15.

抗癌活性を有する新規ヒストン脱アセチル化酵素阻害剤としてのクマリン系N-ヒドロキシシンナムアミド誘導体の設計、合成および生物学的評価

Design, synthesis and biological evaluation of coumarin-based N-hydroxycinnamamide derivatives as novel histone deacetylase inhibitors with anticancer activities.
  • Jiaoli Ding
  • Jing Liu
  • Zhipeng Zhang
  • Jie Guo
  • Maojun Cheng
  • Yang Wan
  • Rikang Wang
  • Yuanying Fang
  • Zhiyu Guan
  • Yi Jin
  • Sai-Sai Xie
  • Bioorg. Chem..2020 Jun;101:104023. S0045-2068(20)31320-1. doi: 10.1016/j.bioorg.2020.104023.Epub 2020-06-17.

一次乳児シリーズ期間中に髄膜炎球菌血清群C結合ワクチンと併用して投与されるDTaP5-HB-IPV-Hibワクチンの無作為化臨床試験

Randomized clinical trial of DTaP5-HB-IPV-Hib vaccine administered concomitantly with meningococcal serogroup C conjugate vaccines during the primary infant series.
  • Jennifer L Oliver
  • Christine Sadorge
  • Florence Boisnard
  • Matthew D Snape
  • Richard Tomlinson
  • Rebecca Mann
  • Peter Rudd
  • Shyam Bhakthavalsala
  • Saul N Faust
  • Paul T Heath
  • Stephen M Hughes
  • Ray Borrow
  • Stéphane Thomas
  • Adam Finn
  • Vaccine.2020 Jul;S0264-410X(20)30787-8. doi: 10.1016/j.vaccine.2020.06.015.Epub 2020-07-09.

妊娠糖尿病に合併した妊娠から降臨した子供の糖尿病/心血管/脳血管疾患関連microRNAの大幅に変化した発現プロファイル-心血管リスクの増加のためのいくつかの可能な理由の一つ

Substantially Altered Expression Profile of Diabetes/Cardiovascular/Cerebrovascular Disease Associated microRNAs in Children Descending from Pregnancy Complicated by Gestational Diabetes Mellitus-One of Several Possible Reasons for an Increased Cardiovascular Risk.
  • Ilona Hromadnikova
  • Katerina Kotlabova
  • Lenka Dvorakova
  • Ladislav Krofta
  • Jan Sirc
  • Cells.2020 Jun;9(6). E1557. doi: 10.3390/cells9061557.Epub 2020-06-26.

ブファリンは、アンドロゲン受容体の脱リン酸化と細胞周期関連キナーゼ分解を介して、B型肝炎ウイルス関連肝細胞癌の発生を抑制することが明らかになった

Bufalin inhibits hepatitis B virus-associated hepatocellular carcinoma development through androgen receptor dephosphorylation and cell cycle-related kinase degradation.
  • Zhuo Yu
  • Hai Feng
  • Yunhui Zhuo
  • Man Li
  • Xiaojun Zhu
  • Lingying Huang
  • Xin Zhang
  • Zhenhua Zhou
  • Chao Zheng
  • Yun Jiang
  • Fan Le
  • Dae-Yeul Yu
  • Alfred Szelok Cheng
  • Xuehua Sun
  • Yueqiu Gao
  • Cell Oncol (Dordr).2020 Jul;10.1007/s13402-020-00546-0. doi: 10.1007/s13402-020-00546-0.Epub 2020-07-04.

フランス本土の羊群におけるHaemonchus contortus集団のイベルメクチンおよびベンズイミダゾールに対する多重耐性、第一報

Multiple-resistance to ivermectin and benzimidazole of a Haemonchus contortus population in a sheep flock from mainland France, first report.
  • T Cazajous
  • F Prevot
  • A Kerbiriou
  • M Milhes
  • C Grisez
  • A Tropee
  • C Godart
  • A Aragon
  • P Jacquiet
  • Vet Parasitol Reg Stud Reports.2018 12;14:103-105. S2405-9390(18)30058-3. doi: 10.1016/j.vprsr.2018.09.005.Epub 2018-09-14.

綿花のα1,3-4-フコシルトランスフェラーゼをコードする遺伝子FucT4は、細胞伸長に重要な役割を果たしており、繊維品質と有意に関連している

A cotton α1,3-/4-fucosyltransferase-encoding gene, FucT4, plays an important role in cell elongation and is significantly associated with fiber quality.
  • Xiaoguang Shang
  • Lijie Zhu
  • Yujia Duan
  • Wangzhen Guo
  • Mol. Genet. Genomics.2020 May;10.1007/s00438-020-01687-5. doi: 10.1007/s00438-020-01687-5.Epub 2020-05-27.

アトラーゼBは、抗補体活性と抗凝固活性を有する新規メタロプロテアーゼであり、不調和な心臓異種移植片の拒絶反応を有意に遅延させる

Atrase B, a novel metalloprotease with anti-complement and anti-coagulant activity, significantly delays discordant cardiac xenograft rejection.
  • Cheng Fu
  • Lei Shi
  • Xia Huang
  • Hao Feng
  • Xiaosheng Tan
  • Song Chen
  • Lan Zhu
  • Qianyun Sun
  • Gang Chen
  • Xenotransplantation.2020 Jun;:e12616. doi: 10.1111/xen.12616.Epub 2020-06-12.

スペイン中部ピレネー山脈の水と植生の動態に及ぼす耕作放棄後の能動的および受動的な土地利用管理の影響

Effects of active and passive land use management after cropland abandonment on water and vegetation dynamics in the Central Spanish Pyrenees.
  • M Khorchani
  • E Nadal-Romero
  • C Tague
  • T Lasanta
  • J Zabalza
  • N Lana-Renault
  • F Domínguez-Castro
  • J Choate
  • Sci. Total Environ..2020 May;717:137160. S0048-9697(20)30670-7. doi: 10.1016/j.scitotenv.2020.137160.Epub 2020-02-07.

ミトコンドリアGWASおよび核-ミトコンドリアエピスタシスとT1DM患者のBMIとの関連

Mitochondrial GWAS and association of nuclear - mitochondrial epistasis with BMI in T1DM patients.
  • Agnieszka H Ludwig-Słomczyńska
  • Michał T Seweryn
  • Przemysław Kapusta
  • Ewelina Pitera
  • Samuel K Handelman
  • Urszula Mantaj
  • Katarzyna Cyganek
  • Paweł Gutaj
  • Łucja Dobrucka
  • Ewa Wender-Ożegowska
  • Maciej T Małecki
  • Paweł P Wołkow
  • BMC Med Genomics.2020 Jul;13(1):97. 10.1186/s12920-020-00752-7. doi: 10.1186/s12920-020-00752-7.Epub 2020-07-07.

亜鉛(II)-亜鉛(II)-銅(II)のアミド官能基化錯体におけるトランスメタレーションとスチレン酸化およびニトロアルドールカップリングへの触媒的応用

Zn(II)-to-Cu(II) Transmetalation in an Amide Functionalized Complex and Catalytic Applications in Styrene Oxidation and Nitroaldol Coupling.
  • Anup Paul
  • Luísa M D R S Martins
  • Anirban Karmakar
  • Maxim L Kuznetsov
  • M Fátima C Guedes da Silva
  • Armando J L Pombeiro
  • Molecules.2020 Jun;25(11). E2644. doi: 10.3390/molecules25112644.Epub 2020-06-06.

1日あたりのタバコを減らすことと、ニコチン含有量が非常に少ないタバコに移行することの両方が、通常のブランドタバコの需要を減少させる

Both reducing cigarettes per day and transitioning to very low-nicotine-content cigarettes decreases demand for usual-brand cigarettes.
  • Tyler D Nighbor
  • Elias M Klemperer
  • John R Hughes
  • Ellaina N Reed
  • Samuel J Simone
  • Julia C West
  • Exp Clin Psychopharmacol.2020 Jul;2020-50178-001. doi: 10.1037/pha0000403.Epub 2020-07-13.

多発性硬化症に起因する持続性特発性顔面痛と中枢神経障害性疼痛に対する反復的経皮的ラジオ波熱凝固療法-レトロスペクティブな単中心解析-

Repetitive percutaneous radiofrequency thermocoagulation for persistent idiopathic facial pain and central neuropathic pain attributed to multiple sclerosis-a retrospective monocentric analysis.
  • Bilal Al Barim
  • Lars Lemcke
  • Michael Schwake
  • Stephanie Schipmann
  • Walter Stummer
  • Acta Neurochir (Wien).2020 Jul;10.1007/s00701-020-04486-4. doi: 10.1007/s00701-020-04486-4.Epub 2020-07-14.

PEワックス形成のためのビスシクロヘプチル縮合ビス(イミノ)ピリジンコバルト触媒：触媒性能と熱安定性に及ぼすフッ化物置換の効果

Bis-cycloheptyl-fused bis(imino)pyridine-cobalt catalysts for PE wax formation: positive effects of fluoride substitution on catalytic performance and thermal stability.
  • Qiuyue Zhang
  • Ningning Wu
  • Junfeng Xiang
  • Gregory A Solan
  • Hongyi Suo
  • Yanping Ma
  • Tongling Liang
  • Wen-Hua Sun
  • Dalton Trans.2020 Jul;49(27):9425-9437. doi: 10.1039/d0dt01876g.

vWF の成熟と放出は、ワイベル-パラード小体の生合成の 2 つの調節因子であるエクソシストと BLOC-2 によって制御されています

vWF maturation and release are controlled by two regulators of Weibel-Palade body biogenesis: exocyst and BLOC-2.
  • Anish Vaibhav Sharda
  • Alexandra M Barr
  • Joshua A Harrison
  • Adrian R Wilkie
  • Chao Fang
  • Lourdes M Mendez
  • Ionita C Ghiran
  • Joseph E Italiano
  • Robert Flaumenhaft
  • Blood.2020 Jul;blood.2020005300. doi: 10.1182/blood.2020005300.Epub 2020-07-02.

左心房低電圧領域のない持続性心房細動における補助的電気生理学的テストガイド付き左心房後壁分離の有効性

Efficacy of an Adjunctive Electrophysiological Test-Guided Left Atrial Posterior Wall Isolation in Persistent Atrial Fibrillation Without a Left Atrial Low Voltage Area.
  • Hirosuke Yamaji
  • Shunichi Higashiya
  • Takashi Murakami
  • Kazuyoshi Hina
  • Hiroshi Kawamura
  • Masaaki Murakami
  • Shigeshi Kamikawa
  • Satoshi Hirohata
  • Shozo Kusachi
  • Circ Arrhythm Electrophysiol.2020 Jul;doi: 10.1161/CIRCEP.119.008191.Epub 2020-07-13.

ブタの心肺蘇生時の脳酸素化と脳代謝に及ぼすアドレナリン投与量の違いによる影響

Effects of different adrenaline doses on cerebral oxygenation and cerebral metabolism during cardiopulmonary resuscitation in pigs.
  • Gabriel Putzer
  • Judith Martini
  • Patrick Spraider
  • Rouven Hornung
  • Daniel Pinggera
  • Julia Abram
  • Niklas Altaner
  • Tobias Hell
  • Bernhard Glodny
  • Raimund Helbok
  • Peter Mair
  • Resuscitation.2020 Jul;S0300-9572(20)30260-4. doi: 10.1016/j.resuscitation.2020.06.024.Epub 2020-07-08.

アヤワスカはメチルフェニデート誘発の条件付き場所選好性の回復を阻害する：行動と脳内Fos発現の評価

Ayahuasca blocks the reinstatement of methylphenidate-induced conditioned place preference in mice: behavioral and brain Fos expression evaluations.
  • Henrique S Reis
  • Isa R S Rodrigues
  • Alexia Anjos-Santos
  • Matheus Libarino-Santos
  • Yasmim A Serra
  • Elisângela G Cata-Preta
  • Daniella Oliveira-Campos
  • Natali D Kisaki
  • Thaísa Barros-Santos
  • Thais S Yokoyama
  • Fabio C Cruz
  • Alexandre J Oliveira-Lima
  • Paulo C R Barbosa
  • Lais F Berro
  • Eduardo A V Marinho
  • Psychopharmacology (Berl.).2020 Jul;10.1007/s00213-020-05609-6. doi: 10.1007/s00213-020-05609-6.Epub 2020-07-16.

特発性レム睡眠行動障害における異質な代謝進行の特徴を明らかにする

Characterizing the heterogeneous metabolic progression in idiopathic REM sleep behavior disorder.
  • Xianhua Han
  • Ping Wu
  • Ian Alberts
  • Hucheng Zhou
  • Huan Yu
  • Panagiotis Bargiotas
  • Igor Yakushev
  • Jian Wang
  • Guenter Höglinger
  • Stefan Förster
  • Claudio Bassetti
  • Wolfgang Oertel
  • Markus Schwaiger
  • Sung-Cheng Huang
  • Paul Cumming
  • Axel Rominger
  • Jiehui Jiang
  • Chuantao Zuo
  • Kuangyu Shi
  • Neuroimage Clin.2020 May;27:102294. S2213-1582(20)30131-5. doi: 10.1016/j.nicl.2020.102294.Epub 2020-05-26.

心臓手術後の術後オピオイド消費に対する超音波ガイド下胸部横筋平面ブロックの有効性。プロスペクティブ、無作為化、二重盲検試験

Efficacy of Ultrasound-Guided Transversus Thoracic Muscle Plane Block on Postoperative Opioid Consumption After Cardiac Surgery: A Prospective, Randomized, Double-Blind Study.
  • Muhammed Enes Aydin
  • Ali Ahiskalioglu
  • Irem Ates
  • Ibrahim Hakki Tor
  • Ferhat Borulu
  • Ozlem Dilara Erguney
  • Mine Celik
  • Nazim Dogan
  • J. Cardiothorac. Vasc. Anesth..2020 Jun;S1053-0770(20)30585-1. doi: 10.1053/j.jvca.2020.06.044.Epub 2020-06-18.

腎移植患者と健常者のウイルス特異的記憶とde novoアロ特異的T細胞応答に対するベラタセプトの効果の違い

Differential effects of Belatacept on virus-specific memory versus de novo allo-specific T cell responses of kidney transplant recipients and healthy donors.
  • Jenny Franziska Kühne
  • Christine Neudörfl
  • Kerstin Beushausen
  • Jana Keil
  • Svitlana Malysheva
  • Franziska Wandrer
  • Hermann Haller
  • Martin Messerle
  • Cornelia Blume
  • Michael Neuenhahn
  • Fabian Schlott
  • Wolfgang Hammerschmidt
  • Reinhard Zeidler
  • Christine S Falk
  • Transpl. Immunol..2020 Aug;61:101291. S0966-3274(19)30167-4. doi: 10.1016/j.trim.2020.101291.Epub 2020-04-21.

膝関節全置換術を受けた関節リウマチ患者におけるトラネキサム酸による先制的抗線溶の有効性：無作為化比較試験のための研究プロトコール

Effectiveness of preemptive antifibrinolysis with tranexamic acid in rheumatoid arthritis patients undergoing total knee arthroplasty: a study protocol for a randomized controlled trial.
  • Yiting Lei
  • Jiacheng Liu
  • Xi Liang
  • Ning Hu
  • Fuxing Pei
  • Wei Huang
  • BMC Musculoskelet Disord.2020 Jul;21(1):465. 10.1186/s12891-020-03488-8. doi: 10.1186/s12891-020-03488-8.Epub 2020-07-15.

ヒドロキサム酸およびベンザミド型ヒストン脱アセチル化酵素阻害剤（HDACi）の遺伝毒性のin vitro評価

In Vitro Assessment of the Genotoxic Hazard of Novel Hydroxamic Acid- and Benzamide-Type Histone Deacetylase Inhibitors (HDACi).
  • Annabelle Friedrich
  • Ann-Sophie Assmann
  • Lena Schumacher
  • Jana V Stuijvenberg
  • Matthias U Kassack
  • Wolfgang A Schulz
  • Wynand P Roos
  • Finn K Hansen
  • Marc Pflieger
  • Thomas Kurz
  • Gerhard Fritz
  • Int J Mol Sci.2020 Jul;21(13). E4747. doi: 10.3390/ijms21134747.Epub 2020-07-03.

Deschloroclozapineは、強力かつ選択的なケモジェニックアクチュエーターであり、マウスやサルの神経細胞や行動の迅速な調節を可能にします

Deschloroclozapine, a potent and selective chemogenetic actuator enables rapid neuronal and behavioral modulations in mice and monkeys.
  • Yuji Nagai
  • Naohisa Miyakawa
  • Hiroyuki Takuwa
  • Yukiko Hori
  • Kei Oyama
  • Bin Ji
  • Manami Takahashi
  • Xi-Ping Huang
  • Samuel T Slocum
  • Jeffrey F DiBerto
  • Yan Xiong
  • Takuya Urushihata
  • Toshiyuki Hirabayashi
  • Atsushi Fujimoto
  • Koki Mimura
  • Justin G English
  • Jing Liu
  • Ken-Ichi Inoue
  • Katsushi Kumata
  • Chie Seki
  • Maiko Ono
  • Masafumi Shimojo
  • Ming-Rong Zhang
  • Yutaka Tomita
  • Jin Nakahara
  • Tetsuya Suhara
  • Masahiko Takada
  • Makoto Higuchi
  • Jian Jin
  • Bryan L Roth
  • Takafumi Minamimoto
  • Nat. Neurosci..2020 Jul;10.1038/s41593-020-0661-3. doi: 10.1038/s41593-020-0661-3.Epub 2020-07-06.

ジブチリルcAMPまたはインターロイキン-6によるアストロサイト分化は、C6グリオーマ細胞におけるマンノース結合レクチン（MBL）-関連セリンプロテアーゼ（MASP）-1/3発現を増強する

Dibutyryl cAMP- or Interleukin-6-induced astrocytic differentiation enhances mannose binding lectin (MBL)-associated serine protease (MASP)-1/3 expression in C6 glioma cells.
  • Valentina Pagliara
  • Maddalena Parafati
  • Annagrazia Adornetto
  • Misti C White
  • Mariorosario Masullo
  • Maurizio Grimaldi
  • Rosaria Arcone
  • Arch. Biochem. Biophys..2018 09;653:39-49. S0003-9861(18)30064-X. doi: 10.1016/j.abb.2018.06.016.Epub 2018-06-28.

親の養育行動の想起と抑うつ性との関連：人口ベースのGutenberg Health Studyにおける第1次移民と非移民の比較

The association between recalled parental rearing behavior and depressiveness: a comparison between 1st immigrants and non-immigrants in the population-based Gutenberg Health Study.
  • Eva M Klein
  • Elmar Brähler
  • Katja Petrowski
  • Ana N Tibubos
  • Mareike Ernst
  • Jörg Wiltink
  • Matthias Michal
  • Philipp S Wild
  • Andreas Schulz
  • Thomas Münzel
  • Jochem König
  • Karl Lackner
  • Norbert Pfeiffer
  • Manfred E Beutel
  • BMC Psychiatry.2020 Jul;20(1):367. 10.1186/s12888-020-02755-1. doi: 10.1186/s12888-020-02755-1.Epub 2020-07-13.

超低出生体重児におけるマンノース結合レクチンおよびマンノース結合タンパク質関連セリンプロテアーゼ2レベルと感染症

Mannose-binding lectin and mannose-binding protein-associated serine protease 2 levels and infection in very-low-birth-weight infants.
  • Annika Hartz
  • Lena Schreiter
  • Julia Pagel
  • Katja Moser
  • Christian Wieg
  • Anneke Grotheer
  • Jan Rupp
  • Egbert Herting
  • Wolfgang Göpel
  • Christoph Härtel
  • Pediatr. Res..2018 07;84(1):134-138. 10.1038/s41390-018-0017-9. doi: 10.1038/s41390-018-0017-9.Epub 2018-05-28.

髭竜アデノウイルス1の完全なゲノム配列には、C型レクチン様ドメインスーパーファミリーのタンパク質をコードする3つの遺伝子が含まれています

The complete genome sequence of bearded dragon adenovirus 1 harbors three genes encoding proteins of the C-type lectin-like domain superfamily.
  • Judit J Pénzes
  • Leonóra Szirovicza
  • Balázs Harrach
  • Infect. Genet. Evol..2020 Sep;83:104321. S1567-1348(20)30152-0. doi: 10.1016/j.meegid.2020.104321.Epub 2020-04-14.

慢性疲労と線維筋痛症の症状は、欠損性統合失調症の重要な構成要素であり、活性化された免疫炎症性経路と強く関連している

Chronic fatigue and fibromyalgia symptoms are key components of deficit schizophrenia and are strongly associated with activated immune-inflammatory pathways.
  • Abbas F Almulla
  • Hussein Kadhem Al-Hakeim
  • Mokhlad Swadi Abed
  • Andre F Carvalho
  • Michael Maes
  • Schizophr. Res..2020 May;S0920-9964(20)30255-3. doi: 10.1016/j.schres.2020.05.003.Epub 2020-05-26.

日本における野生型トランススチレチンアミロイド心筋症の臨床的特徴と自然史

Clinical characteristics and natural history of wild-type transthyretin amyloid cardiomyopathy in Japan.
  • Toshihiro Yamada
  • Seiji Takashio
  • Yuichiro Arima
  • Masato Nishi
  • Mami Morioka
  • Kyoko Hirakawa
  • Shinsuke Hanatani
  • Koichiro Fujisue
  • Kenshi Yamanaga
  • Hisanori Kanazawa
  • Daisuke Sueta
  • Satoshi Araki
  • Hiroki Usuku
  • Taishi Nakamura
  • Satoru Suzuki
  • Eiichiro Yamamoto
  • Mitsuharu Ueda
  • Koichi Kaikita
  • Kenichi Tsujita
  • ESC Heart Fail.2020 Jul;doi: 10.1002/ehf2.12884.Epub 2020-07-16.

ポルト-全身性シャント-小児における高アンドロゲン血症のまれな原因。2例の症例報告と文献のレビュー

Porto-systemic shunt - a rare cause of hyperandrogenism in children. Two case reports and review of literature.
  • Mikołaj Danko
  • Anna Malinowska
  • Elżbieta Moszczyńska
  • Joanna Pawłowska
  • Maria Szarras-Czapnik
  • Małgorzata Walewska-Wolf
  • Urszula Wątrobińska
  • Mieczysław Szalecki
  • J. Pediatr. Endocrinol. Metab..2020 Jul;/j/jpem.ahead-of-print/jpem-2020-0123/jpem-2020-0123.xml. doi: 10.1515/jpem-2020-0123.Epub 2020-07-13.

パルバルブミン発現および非特異的GABAニューロンからのCA1錐体細胞へのGABA放出は、マウス海馬のシナプス前GABA受容体によって異なって調節されている

GABA releases from parvalbumin-expressing and unspecific GABAergic neurons onto CA1 pyramidal cells are differentially modulated by presynaptic GABA receptors in mouse hippocampus.
  • Yingqian Liu
  • Xingwu Jordan Yang
  • Haiping Xia
  • Cha-Min Tang
  • Kun Yang
  • Biochem. Biophys. Res. Commun..2019 12;520(2):449-452. S0006-291X(19)31933-3. doi: 10.1016/j.bbrc.2019.10.044.Epub 2019-10-10.

喘息やその他の呼吸器疾患におけるスフィンゴシン-1-リン酸の役割をLuminex社のマルチプル・アナリティクス・プロファイリング技術を用いた次世代知識発見プラットフォームで解明

Decoding the Role of Sphingosine-1-Phosphate in Asthma and Other Respiratory System Diseases Using Next Generation Knowledge Discovery Platforms Coupled With Luminex Multiple Analyte Profiling Technology.
  • Sami Bahlas
  • Laila A Damiati
  • Ayman S Al-Hazmi
  • Peter Natesan Pushparaj
  • Front Cell Dev Biol.2020;8:444. doi: 10.3389/fcell.2020.00444.Epub 2020-06-19.

再生歯内療法で使用されている従来の3種類の抗生物質ペーストと修正された3種類の抗生物質ペーストによって誘発された歯の変色の比較分析

Comparative analysis of tooth discoloration induced by conventional and modified triple antibiotic pastes used in regenerative endodontics.
  • Meenakshi Venkataraman
  • Somya Singhal
  • Aseem P Tikku
  • Anil Chandra
  • Indian J Dent Res.2019 Nov-Dec;30(6):933-936. IndianJDentRes_2019_30_6_933_275883. doi: 10.4103/ijdr.IJDR_782_18.

腸管上皮細胞とシークレットームを介した相互作用。セロバール・チフス菌のセクレトームおよびTNF-α誘導性炎症反応の減衰におけるR0011由来のセクレトーム成分の役割

Secretome-Mediated Interactions with Intestinal Epithelial Cells: A Role for Secretome Components from R0011 in the Attenuation of Serovar Typhimurium Secretome and TNF-α-Induced Proinflammatory Responses.
  • Michael P Jeffrey
  • Chad W MacPherson
  • Olivier Mathieu
  • Thomas A Tompkins
  • Julia M Green-Johnson
  • J. Immunol..2020 May;204(9):2523-2534. jimmunol.1901440. doi: 10.4049/jimmunol.1901440.Epub 2020-04-01.

シェーグレン症候群における唾液腺超音波スコアリングシステムのビデオクリップ評価：OMERACT超音波ワーキンググループの信頼性演習

Video clip assessment of a salivary gland ultrasound scoring system in Sjögren's syndrome using consensual definitions: an OMERACT ultrasound working group reliability exercise.
  • Sandrine Jousse-Joulin
  • Maria Antonietta D'Agostino
  • Celine Nicolas
  • Esperanza Naredo
  • Sarah Ohrndorf
  • Marina Backhaus
  • Giorgio Tamborrini
  • Isabelle Chary-Valckenaere
  • Lene Terslev
  • Annamaria Iagnocco
  • Paz Collado
  • Cristina Hernández-Díaz
  • Frederique Gandjbakhch
  • Wolfgang A Schmidt
  • Georgios Filippou
  • Christian Dejaco
  • Martin Helmut Stradner
  • Mohamed Atia Mortada
  • Alojzija Hočevar
  • Stavros Chrysidis
  • Ghada El Mardenly
  • Juan José de Agustín
  • Ralf Thiele
  • Daryl K MacCarter
  • Stephanie Finzel
  • Petra Hanova
  • Alen Zabotti
  • Cornelia Glaser
  • Zarrin Alavi
  • Daniel Sten Hammenfors
  • Florence Gatineau
  • George Aw Bruyn
  • Ann. Rheum. Dis..2019 07;78(7):967-973. annrheumdis-2019-215024. doi: 10.1136/annrheumdis-2019-215024.Epub 2019-04-29.

Grb7乳がん標的の環状ペプチド阻害剤の評価。カーゴの小さな変化が細胞活性の大きな変化をもたらす

Evaluation of Cyclic Peptide Inhibitors of the Grb7 Breast Cancer Target: Small Change in Cargo Results in Large Change in Cellular Activity.
  • Jianrong Sang
  • Ketav Kulkarni
  • Gabrielle M Watson
  • Xiuquan Ma
  • David J Craik
  • Sónia T Henriques
  • Aaron G Poth
  • Aurélie H Benfield
  • Jacqueline A Wilce
  • Molecules.2019 Oct;24(20). E3739. doi: 10.3390/molecules24203739.Epub 2019-10-17.

"エクシフォイド下チューブ心膜切開術とコンピュータ断層撮影による心嚢液貯留の治療-あるいは心エコー-ガイド付き経皮カテーテルドレナージ法" へのコメント

Comments on "Treatment of Pericardial Effusion Through Subxiphoid Tube Pericardiostomy and Computerized Tomography - Or Echocardiography - Guided Percutaneous Catheter Drainage Methods".
  • Kyriakos Spiliopoulos
  • Dimitrios Magouliotis
  • John Skoularigis
  • Filippos Triposkiadis
  • Braz J Cardiovasc Surg.2019 12;34(5):642. doi: 10.21470/1678-9741-2019-0331.Epub 2019-12-01.

Lactobacillus rhamnosus D1 または Weissella paramesenteroides GIR16L4 またはその両方をスターター培養したチーズにおける黄色ブドウ球菌の生存性とその毒素（SEC および TSST-1）の発現について検討した

Viability of Staphylococcus aureus and expression of its toxins (SEC and TSST-1) in cheeses using Lactobacillus rhamnosus D1 or Weissella paramesenteroides GIR16L4 or both as starter cultures.
  • G O Silva
  • R D Castro
  • L G Oliveira
  • F M Sant'Anna
  • C D Barbosa
  • S H C Sandes
  • R S Silva
  • M F S Resende
  • A M Q Lana
  • A C Nunes
  • M M O P Cerqueira
  • M R Souza
  • J. Dairy Sci..2020 May;103(5):4100-4108. S0022-0302(20)30205-8. doi: 10.3168/jds.2018-16037.Epub 2020-03-18.

バシトラシンのsub-MICによって誘導された細胞エンベロープストレスに応答して、細胞外DNA依存性バイオフィルム内に耐性遺伝子を拡散させる潜在的なリスク

Potential risk to spread resistant genes within the extracellular DNA-dependent biofilm of in response to cell envelope stress induced by sub-MIC of bacitracin.
  • Ryo Nagasawa
  • Tsutomu Sato
  • Nobuhiko Nomura
  • Tomoyo Nakamura
  • Hidenobu Senpuku
  • Appl. Environ. Microbiol..2020 Jun;AEM.00770-20. doi: 10.1128/AEM.00770-20.Epub 2020-06-12.

末梢血中の() mRNAの発現レベルは、乳がんの再発を予測するための潜在的なバイオマーカーである

The Expression Level of () mRNA in Peripheral Blood Is a Potential Biomarker for Predicting Recurrence in Breast Cancer.
  • Takaaki Masuda
  • Miwa Noda
  • Akihiro Kitagawa
  • Qingjiang Hu
  • Atsushi Fujii
  • Shuhei Ito
  • Keisuke Kosai
  • Yuki Ando
  • Yoshihiro Matsumoto
  • Hajime Ohtsu
  • Hiroki Uchida
  • Shinji Ohno
  • Koshi Mimori
  • Anticancer Res..2020 Jul;40(7):3733-3742. 40/7/3733. doi: 10.21873/anticanres.14362.

遺伝学的解析により、家族性症候群性拡張型心筋症の鑑別診断が可能となった。アルストレム症候群の新しい症例

Genetic analysis resolves differential diagnosis of a familial syndromic dilated cardiomyopathy: A new case of Alström syndrome.
  • Barbara Lombardo
  • Valeria D'Argenio
  • Emanuele Monda
  • Andrea Vitale
  • Martina Caiazza
  • Lucia Sacchetti
  • Lucio Pastore
  • Giuseppe Limongelli
  • Giulia Frisso
  • Cristina Mazzaccara
  • Mol Genet Genomic Med.2020 Jul;8(7):e1260. doi: 10.1002/mgg3.1260.Epub 2020-05-12.

アルベンダゾールとメトロニダゾールの光触媒オゾン化反応における各種紫外線照射の重要な役割を検討した。統合化と相乗的反応機構の解明

Scrutinizing the vital role of various ultraviolet irradiations on the comparative photocatalytic ozonation of albendazole and metronidazole: Integration and synergistic reactions mechanism.
  • Mehrangiz Fathinia
  • Alireza Khataee
  • Behrouz Vahid
  • Sang Woo Joo
  • J. Environ. Manage..2020 Jul;272:111044. S0301-4797(20)30972-5. doi: 10.1016/j.jenvman.2020.111044.Epub 2020-07-14.

溶存ニッケルとニッケルに汚染された懸濁液が強アルカリ性のサンゴである Acropora muricata に及ぼす影響

Effects of dissolved nickel and nickel-contaminated suspended sediment on the scleractinian coral, Acropora muricata.
  • Megan L Gillmore
  • Francesca Gissi
  • Lisa A Golding
  • Jenny L Stauber
  • Amanda J Reichelt-Brushett
  • Andrea Severati
  • Craig A Humphrey
  • Dianne F Jolley
  • Mar. Pollut. Bull..2020 Mar;152:110886. S0025-326X(20)30004-7. doi: 10.1016/j.marpolbul.2020.110886.Epub 2020-02-17.

プロパンアミド鎖を有する新規6-メトキシベンゾチアゾール-ピペラジン誘導体の合成、抗菌性、抗酸化性および分子ドッキング研究

Synthesis, Antimicrobial, Antioxidant and Molecular Docking Studies on Novel 6-Methoxybenzothiazole-piperazine Derivatives with Propanamide Chain.
  • Nesrin Atiah Alhusadi
  • Bengisu Turgutalp
  • Inci Deniz
  • Ebru Turkoz Acar
  • Hande Sipahi
  • Mine Yarim
  • Enise Ece Gurdal
  • Curr Top Med Chem.2020 Jun;CTMC-EPUB-107442. doi: 10.2174/1568026620666200618122500.Epub 2020-06-18.

抗CD22 90Y-エプラツズマブテトラキセタンと抗CD20ベルツズマブの併用療法：再発・難治性の侵攻性非ホジキンリンパ腫患者を対象とした第I相試験

Anti-CD22 90Y-epratuzumab tetraxetan combined with anti-CD20 veltuzumab: a phase I study in patients with relapsed/refractory, aggressive non-Hodgkin lymphoma.
  • Thomas E Witzig
  • Michael B Tomblyn
  • Jamal G Misleh
  • Ebenezer A Kio
  • Robert M Sharkey
  • William A Wegener
  • David M Goldenberg
  • Haematologica.2014 Nov;99(11):1738-45. haematol.2014.112110. doi: 10.3324/haematol.2014.112110.Epub 2014-08-22.

全ゲノムシークエンシングにより、家族性アルストローム症候群患者において、まれな2価のALMS1ミスセンス変異とストップゲイン変異が同定されました

Whole exome sequencing identifies rare biallelic ALMS1 missense and stop gain mutations in familial Alström syndrome patients.
  • Naglaa M Kamal
  • Ahmed N Sahly
  • Babajan Banaganapalli
  • Omran M Rashidi
  • Preetha J Shetty
  • Jumana Y Al-Aama
  • Noor A Shaik
  • Ramu Elango
  • Omar I Saadah
  • Saudi J Biol Sci.2020 Jan;27(1):271-278. S1319-562X(19)30168-8. doi: 10.1016/j.sjbs.2019.09.006.Epub 2019-09-11.

クロザピン投与ラットの心臓、腎臓、免疫障害を減衰させるスルピリドの役割：Kim-1、TIMP-1、CYPアイソフォームをコードする遺伝子のmRNA発現パターン

The role of sulpiride in attenuating the cardiac, renal, and immune disruptions in rats receiving clozapine: mRNA expression pattern of the genes encoding Kim-1, TIMP-1, and CYP isoforms.
  • Amany T Mohammed
  • Samah R Khalil
  • Fagr A Mahmoud
  • Gamal A Elmowalid
  • Haytham A Ali
  • Hamed A El-Serehy
  • Mohamed M Abdel-Daim
  • Environ Sci Pollut Res Int.2020 Jul;27(20):25404-25414. 10.1007/s11356-020-08914-x. doi: 10.1007/s11356-020-08914-x.Epub 2020-04-29.

リモートセンシング、同位体組成とメタゲノム解析により、ドセ川鉱石の噴煙がアブロルホス銀行南部の岩礁に到達したことが明らかになった

Remote sensing, isotopic composition and metagenomics analyses revealed Doce River ore plume reached the southern Abrolhos Bank Reefs.
  • Ronaldo B Francini-Filho
  • Marcelle C Cordeiro
  • Claudia Y Omachi
  • André M Rocha
  • Laura Bahiense
  • Gizele D Garcia
  • Diogo Tschoeke
  • Marcelo G de Almeida
  • Thiago P Rangel
  • Braulio Cherene Vaz De Oliveira
  • Diogo Q R de Almeida
  • Rafael Menezes
  • Eric F Mazzei
  • Jean-Christophe Joyeux
  • Carlos E Rezende
  • Cristiane C Thompson
  • Fabiano L Thompson
  • Sci. Total Environ..2019 Dec;697:134038. S0048-9697(19)34015-X. doi: 10.1016/j.scitotenv.2019.134038.Epub 2019-08-29.

ガソリンスタンドアテンダントにおける免疫・炎症・酸化ストレスバイオマーカーの評価

Evaluation of immunological, inflammatory, and oxidative stress biomarkers in gasoline station attendants.
  • Angela Maria Moro
  • Elisa Sauer
  • Natália Brucker
  • Mariele Feiffer Charão
  • Bruna Gauer
  • Sabrina Nunes do Nascimento
  • Gabriela Goethel
  • Marta Maria Medeiros Frescura Duarte
  • Solange Cristina Garcia
  • BMC Pharmacol Toxicol.2019 12;20(Suppl 1):75. 10.1186/s40360-019-0355-1. doi: 10.1186/s40360-019-0355-1.Epub 2019-12-19.

マンニトールはヒト小気管支の肥満細胞依存性収縮を誘発し、プロスタサイクリンによる気管支保護作用を示した

Mannitol triggers mast cell-dependent contractions of human small bronchi and prostacyclin bronchoprotection.
  • Jesper Säfholm
  • Martijn L Manson
  • Johan Bood
  • Mamdoh Al-Ameri
  • Ann-Charlotte Orre
  • Johan Raud
  • Sven-Erik Dahlén
  • Mikael Adner
  • J. Allergy Clin. Immunol..2019 10;144(4):984-992. S0091-6749(19)30763-8. doi: 10.1016/j.jaci.2019.04.031.Epub 2019-06-14.

ロシア・シベリアのIxodes persulcatus/Ixodes trianguliceps同属地域における小型哺乳類およびマダニに循環するAnaplasmataceaeの遺伝的変動

Genetic variability of Anaplasmataceae circulating in small mammals and ticks in an Ixodes persulcatus/Ixodes trianguliceps sympatric area in Russian Siberia.
  • Vera Rar
  • Valeriy Yakimenko
  • Artem Tikunov
  • Marat Makenov
  • Tamara Epikhina
  • Aleksey Tancev
  • Nina Tikunova
  • Ticks Tick Borne Dis.2020 Jun;:101499. S1877-959X(20)30147-3. doi: 10.1016/j.ttbdis.2020.101499.Epub 2020-06-28.

ピノセンブリンは、N-カドヘリンとGABAB受容体のmRNAレベルを低下させることにより、卵巣がん細胞の増殖・遊走を抑制し、アポトーシスを促進する

Pinocembrin inhibits the proliferation and migration and promotes the apoptosis of ovarian cancer cells through down-regulating the mRNA levels of N-cadherin and GABAB receptor.
  • Jun Gao
  • Shixin Lin
  • Yao Gao
  • Xia Zou
  • Jun Zhu
  • Man Chen
  • Hong Wan
  • Hong Zhu
  • Biomed. Pharmacother..2019 Dec;120:109505. S0753-3322(19)31606-3. doi: 10.1016/j.biopha.2019.109505.Epub 2019-10-18.

β3アドレナリンと甲状腺ホルモンのシグナル統合を介した脂肪細胞の熱発育と脂肪形成の制御

Control of Adipocyte Thermogenesis and Lipogenesis through β3-Adrenergic and Thyroid Hormone Signal Integration.
  • Adilson Guilherme
  • Batuhan Yenilmez
  • Alexander H Bedard
  • Felipe Henriques
  • Dianxin Liu
  • Alexandra Lee
  • Lauren Goldstein
  • Mark Kelly
  • Sarah M Nicoloro
  • Min Chen
  • Lee Weinstein
  • Sheila Collins
  • Michael P Czech
  • Cell Rep.2020 May;31(5):107598. S2211-1247(20)30547-7. doi: 10.1016/j.celrep.2020.107598.

機械学習技術を用いた肝内胆管癌表現型の新しい分類。国際的な多施設での分析

A Novel Classification of Intrahepatic Cholangiocarcinoma Phenotypes Using Machine Learning Techniques: An International Multi-Institutional Analysis.
  • Diamantis I Tsilimigras
  • J Madison Hyer
  • Anghela Z Paredes
  • Adrian Diaz
  • Dimitrios Moris
  • Alfredo Guglielmi
  • Luca Aldrighetti
  • Matthew Weiss
  • Todd W Bauer
  • Sorin Alexandrescu
  • George A Poultsides
  • Shishir K Maithel
  • Hugo P Marques
  • Guillaume Martel
  • Carlo Pulitano
  • Feng Shen
  • Olivier Soubrane
  • Bas Groot Koerkamp
  • Itaru Endo
  • Timothy M Pawlik
  • Ann. Surg. Oncol..2020 Jun;10.1245/s10434-020-08696-z. doi: 10.1245/s10434-020-08696-z.Epub 2020-06-03.

Siewert 2型食道胃接合部腺癌に対する胃全摘術時の経口腔内挿入型アンビル法による食道結腸吻合術と円形ステープラーを用いた体外吻合術の安全性を検討した

The safety of esophagojejunostomy via a transorally inserted-anvil method vs extracorporeal anastomosis using a circular stapler during total gastrectomy for Siewert type 2 adenocarcinoma of the esophagogastric junction.
  • Xin-Hua Chen
  • Yan-Feng Hu
  • Jun Luo
  • Yue-Hong Chen
  • Hao Liu
  • Tian Lin
  • Hao Chen
  • Guo-Xin Li
  • Jiang Yu
  • Gastroenterol Rep (Oxf).2020 Jun;8(3):242-251. goz046. doi: 10.1093/gastro/goz046.Epub 2019-10-11.

イネの茎の成長過程におけるジベレリン酸応答の拮抗的制御

Antagonistic regulation of the gibberellic acid response during stem growth in rice.
  • Keisuke Nagai
  • Yoshinao Mori
  • Shin Ishikawa
  • Tomoyuki Furuta
  • Rico Gamuyao
  • Yoko Niimi
  • Tokunori Hobo
  • Moyuri Fukuda
  • Mikiko Kojima
  • Yumiko Takebayashi
  • Atsushi Fukushima
  • Yasuyo Himuro
  • Masatomo Kobayashi
  • Wataru Ackley
  • Hiroshi Hisano
  • Kazuhiro Sato
  • Aya Yoshida
  • Jianzhong Wu
  • Hitoshi Sakakibara
  • Yutaka Sato
  • Hiroyuki Tsuji
  • Takashi Akagi
  • Motoyuki Ashikari
  • Nature.2020 Jul;10.1038/s41586-020-2501-8. doi: 10.1038/s41586-020-2501-8.Epub 2020-07-15.

心臓移植片血管障害の長期転帰：国際心臓肺移植学会の血管造影評価尺度の重要性

Long-term outcome of cardiac allograft vasculopathy: Importance of the International Society for Heart and Lung Transplantation angiographic grading scale.
  • Jan M Van Keer
  • Lucas N L Van Aelst
  • Filip Rega
  • Walter Droogne
  • Gabor Voros
  • Bart Meyns
  • Johan Vanhaecke
  • Marie-Paule Emonds
  • Stefan Janssens
  • Maarten Naesens
  • Johan Van Cleemput
  • J. Heart Lung Transplant..2019 11;38(11):1189-1196. S1053-2498(19)31623-7. doi: 10.1016/j.healun.2019.08.005.Epub 2019-08-10.

退役軍人健康局のカイロプラクティックサービス利用率を予測するための教師付き機械学習アプローチの検討

Exploring supervised machine learning approaches to predicting Veterans Health Administration chiropractic service utilization.
  • Brian C Coleman
  • Samah Fodeh
  • Anthony J Lisi
  • Joseph L Goulet
  • Kelsey L Corcoran
  • Harini Bathulapalli
  • Cynthia A Brandt
  • Chiropr Man Therap.2020 Jul;28(1):47. 10.1186/s12998-020-00335-4. doi: 10.1186/s12998-020-00335-4.Epub 2020-07-17.

CD28およびCTLA-4受容体による入れ子状拮抗フィードバック回路を介した定足数制御は、T細胞集団のダイナミクスに頑健性をもたらす

Quorum Regulation via Nested Antagonistic Feedback Circuits Mediated by the Receptors CD28 and CTLA-4 Confers Robustness to T Cell Population Dynamics.
  • Simon Zenke
  • Margriet M Palm
  • Julia Braun
  • Alina Gavrilov
  • Philippa Meiser
  • Jan P Böttcher
  • Niklas Beyersdorf
  • Stephan Ehl
  • Audrey Gerard
  • Tim Lämmermann
  • Ton N Schumacher
  • Joost B Beltman
  • Jan C Rohr
  • Immunity.2020 02;52(2):313-327.e7. S1074-7613(20)30046-7. doi: 10.1016/j.immuni.2020.01.018.Epub 2020-02-11.

フォアガット線虫Haemonchus contortusと薬用植物は、実験的に感染した子羊の糞便微生物群集に影響を与えることができるか？

Can the foregut nematode Haemonchus contortus and medicinal plants influence the fecal microbial community of the experimentally infected lambs?
  • Dominika Mravčáková
  • Svetlana Kišidayová
  • Anna Kopčáková
  • Peter Pristaš
  • Jana Pisarčíková
  • Magda Bryszak
  • Adam Cieslak
  • Marián Várady
  • Zora Váradyová
  • PLoS ONE.2020;15(6):e0235072. PONE-D-20-00728. doi: 10.1371/journal.pone.0235072.Epub 2020-06-23.

DNAメタバーコーディングによる食餌解析から推定される地中げっ歯類の生態的特殊化とニッチ重複

Ecological specialization and niche overlap of subterranean rodents inferred from DNA metabarcoding diet analysis.
  • Carla Martins Lopes
  • Marta De Barba
  • Frédéric Boyer
  • Céline Mercier
  • Daniel Galiano
  • Bruno Busnello Kubiak
  • Renan Maestri
  • Pedro Joel Silva da Silva Filho
  • Ludovic Gielly
  • Eric Coissac
  • Thales Renato Ochotorena de Freitas
  • Pierre Taberlet
  • Mol. Ecol..2020 Jul;doi: 10.1111/mec.15549.Epub 2020-07-12.

タンデム遺伝子の重複は、植物におけるカフェインとクロシン生合成経路の発散的進化を促進する

Tandem gene duplications drive divergent evolution of caffeine and crocin biosynthetic pathways in plants.
  • Zhichao Xu
  • Xiangdong Pu
  • Ranran Gao
  • Olivia Costantina Demurtas
  • Steven J Fleck
  • Michaela Richter
  • Chunnian He
  • Aijia Ji
  • Wei Sun
  • Jianqiang Kong
  • Kaizhi Hu
  • Fengming Ren
  • Jiejie Song
  • Zhe Wang
  • Ting Gao
  • Chao Xiong
  • Haoying Yu
  • Tianyi Xin
  • Victor A Albert
  • Giovanni Giuliano
  • Shilin Chen
  • Jingyuan Song
  • BMC Biol..2020 Jun;18(1):63. 10.1186/s12915-020-00795-3. doi: 10.1186/s12915-020-00795-3.Epub 2020-06-18.

渓流や湖沼の堆積物の生物学的質を評価するための豊富さに基づいた指標としてのオリゴチャイテムのハイスループットDNAバーコード化

High-throughput DNA barcoding of oligochaetes for abundance-based indices to assess the biological quality of sediments in streams and lakes.
  • Régis Vivien
  • Laure Apothéloz-Perret-Gentil
  • Jan Pawlowski
  • Inge Werner
  • Michel Lafont
  • Benoit J D Ferrari
  • Sci Rep.2020 Feb;10(1):2041. 10.1038/s41598-020-58703-2. doi: 10.1038/s41598-020-58703-2.Epub 2020-02-06.

ミトコンドリア核タンパク質のダイナミクスと活性酸素種の制御を超解像イメージングで明らかにした多応答蛍光プローブ

A Multi-responsive Fluorescent Probe Reveals Mitochondrial Nucleoprotein Dynamics with Reactive Oxygen Species Regulation through Super-resolution Imaging.
  • Guanqing Yang
  • Zhengjie Liu
  • Ruilong Zhang
  • Xiaohe Tian
  • Juan Chen
  • Guangmei Han
  • Bianhua Liu
  • Xinya Han
  • Yao Fu
  • Zhangjun Hu
  • Zhongping Zhang
  • Angew. Chem. Int. Ed. Engl..2020 Jun;doi: 10.1002/anie.202005959.Epub 2020-06-22.

B型肝炎ウイルス関連急性・慢性肝不全に対するグルココルチコイド対従来の治療。システマティックレビューおよびメタアナリシス

Glucocorticoid versus traditional therapy for hepatitis B virus-related acute-on-chronic liver failure: A systematic review and meta-analysis.
  • Ranran Gao
  • Yang Li
  • Yang Cao
  • Rongjiong Zheng
  • Li Tang
  • Jianzhong Yang
  • Xiaobo Lu
  • Medicine (Baltimore).2020 Jun;99(25):e20604. 00005792-202006190-00037. doi: 10.1097/MD.0000000000020604.

Irp2は鉄を介したCdkal1触媒によるtRNA修飾を介してインスリン産生を制御している

Irp2 regulates insulin production through iron-mediated Cdkal1-catalyzed tRNA modification.
  • Maria C Ferreira Dos Santos
  • Cole P Anderson
  • Susanne Neschen
  • Kimberly B Zumbrennen-Bullough
  • Steven J Romney
  • Melanie Kahle-Stephan
  • Birgit Rathkolb
  • Valerie Gailus-Durner
  • Helmut Fuchs
  • Eckhard Wolf
  • Jan Rozman
  • Martin Hrabe de Angelis
  • Weiling Maggie Cai
  • Malini Rajan
  • Jennifer Hu
  • Peter C Dedon
  • Elizabeth A Leibold
  • Nat Commun.2020 01;11(1):296. 10.1038/s41467-019-14004-5. doi: 10.1038/s41467-019-14004-5.Epub 2020-01-15.

COVID-19の地域有病率低下期における医療従事者間のSARS-CoV-2感染を効果的にコントロールする

Effective control of SARS-CoV-2 transmission between healthcare workers during a period of diminished community prevalence of COVID-19.
  • Nick K Jones
  • Lucy Rivett
  • Dominic Sparkes
  • Sally Forrest
  • Sushmita Sridhar
  • Jamie Young
  • Joana Pereira-Dias
  • Claire Cormie
  • Harmeet Gill
  • Nicola Reynolds
  • Michelle Wantoch
  • Matthew Routledge
  • Ben Warne
  • Jack Levy
  • William David Córdova Jiménez
  • Fathima Nisha Begum Samad
  • Chris McNicholas
  • Mark Ferris
  • Jane Gray
  • Michael Gill
  • Stephen Baker
  • John Bradley
  • Gordon Dougan
  • Ian Goodfellow
  • Ravi Gupta
  • Paul J Lehner
  • Paul A Lyons
  • Nicholas J Matheson
  • Kenneth Gc Smith
  • M Estee Torok
  • Mark Toshner
  • Martin D Curran
  • Stewart Fuller
  • Afzal Chaudhry
  • Ashley Shaw
  • John R Bradley
  • Gregory J Hannon
  • Ian G Goodfellow
  • Gordon Dougan
  • Kenneth Gc Smith
  • Paul J Lehner
  • Giles Wright
  • Nicholas J Matheson
  • Stephen Baker
  • Michael P Weekes
  • Elife.2020 06;9. e59391. doi: 10.7554/eLife.59391.Epub 2020-06-19.

PUF60およびU2AF65のRNA認識モチーフにおけるがん関連の置換により、正しいフォールディングと3'スプライスサイト選択に必要な残基が明らかになった

Cancer-Associated Substitutions in RNA Recognition Motifs of PUF60 and U2AF65 Reveal Residues Required for Correct Folding and 3' Splice-Site Selection.
  • Jana Kralovicova
  • Ivana Borovska
  • Monika Kubickova
  • Peter J Lukavsky
  • Igor Vorechovsky
  • Cancers (Basel).2020 Jul;12(7). E1865. doi: 10.3390/cancers12071865.Epub 2020-07-11.

肺大切除術における非挿管型ユニポータルビデオ支援胸部手術の手術困難度を管理するための変換法：挿管なしの単純な胸腔切開術

Conversion method to manage surgical difficulties in non-intubated uniportal video-assisted thoracic surgery for major lung resection: simple thoracotomy without intubation.
  • József Furák
  • Zsolt Szabó
  • Tamás Tánczos
  • Attila Paszt
  • Anna Rieth
  • Tibor Németh
  • Balázs Pécsy
  • Aurél Ottlakán
  • Ferenc Rárosi
  • György Lázár
  • Zsolt Molnár
  • J Thorac Dis.2020 May;12(5):2061-2069. jtd-12-05-2061. doi: 10.21037/jtd-19-3830.

スプライシング欠損を引き起こす新規ABCA4欠失挿入変異による偽優性スターガルト病の血統における表現型-遺伝子型の相関性

Phenotype-genotype correlations in a pseudodominant Stargardt disease pedigree due to a novel ABCA4 deletion-insertion variant causing a splicing defect.
  • Di Huang
  • Jennifer A Thompson
  • Jason Charng
  • Enid Chelva
  • Samuel McLenachan
  • Shang-Chih Chen
  • Dan Zhang
  • Terri L McLaren
  • Tina M Lamey
  • Ian J Constable
  • John N De Roach
  • May Thandar Aung-Htut
  • Abbie Adams
  • Sue Fletcher
  • Steve D Wilton
  • Fred K Chen
  • Mol Genet Genomic Med.2020 Jul;8(7):e1259. doi: 10.1002/mgg3.1259.Epub 2020-04-23.

トリヨードチロニンは、分化したTHP-1マクロファージの甲状腺ホルモン受容体αを介して、シリカ誘発性酸化ストレス、炎症、アポトーシスを抑制する

Triiodothyronine Attenuates Silica-Induced Oxidative Stress, Inflammation, and Apoptosis via Thyroid Hormone Receptor α in Differentiated THP-1 Macrophages.
  • Shiming Gan
  • Meng Yang
  • Lieyang Fan
  • Li Xie
  • Yiju Xu
  • Bin Wang
  • Tao Xu
  • Linling Yu
  • Jixuan Ma
  • Weihong Chen
  • Chem. Res. Toxicol..2020 May;33(5):1256-1265. doi: 10.1021/acs.chemrestox.0c00018.Epub 2020-04-03.

内視鏡下手術へのアプローチ。コロナウイルス病2019年患者を対象とした第四大学紹介センターからのルーティンプロトコール

Approach to Endoscopic Procedures: A Routine Protocol from a Quaternary University Referral Center Exclusively for Coronavirus Disease 2019 Patients.
  • Tomazo Antonio Prince Franzini
  • Ana Paula Samy Tanaka Kotinda
  • Diogo Turiani Hourneaux de Moura
  • Márcia Lopes Vicente Badana
  • Marion Sielfeld de Medeiros
  • Patrícia Goulart Rodrigues Lima
  • Brigitte Feiner de Mello
  • Rafael Priante Kayano
  • Maria José Carvalho Carmona
  • Marcelo Cristiano Rocha
  • Aléia Faustina Campos
  • Thomas R McCarty
  • Thaís Guimarães
  • Maria Luisa do Nascimento Moura
  • Christopher C Thompson
  • Eduardo Guimarães Hourneaux de Moura
  • Clinics (Sao Paulo).2020;75:e1989. S1807-59322020000100240. doi: 10.6061/clinics/2020/e1989.Epub 2020-06-12.