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日本語AIでPubMedを検索

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日本語AIでPubMedを検索

PubMedの提供する医学論文データベースを日本語で検索できます。AI(Deep Learning)を活用した機械翻訳エンジンにより、精度高く日本語へ翻訳された論文をご参照いただけます。
対象期間    ～ 

2020年07月 みんなが読んでいる論文

分子ドッキングを用いたSARS-CoV-2 3CLproとアンジオテンシン変換酵素IIの標的化によるCOVID-19に対する漢方薬の可能性のインシリコスクリーニング

In Silico Screening of Potential Chinese Herbal Medicine Against COVID-19 by Targeting SARS-CoV-2 3CLpro and Angiotensin Converting Enzyme II Using Molecular Docking.
  • Liang-Qin Gao
  • Jing Xu
  • Shao-Dong Chen
  • Chin J Integr Med.2020 Jul;26(7):527-532. 10.1007/s11655-020-3476-x. doi: 10.1007/s11655-020-3476-x.Epub 2020-07-06.

McCune Albright症候群は、GNAS体細胞変異に関連した膵臓癌の膵管内乳頭および粘液性新生物への遺伝的素因である - 症例報告

McCune Albright syndrome is a genetic predisposition to intraductal papillary and mucinous neoplasms of the pancreas associated pancreatic cancer in relation with GNAS somatic mutation - a case report.
  • Sébastien Gaujoux
  • Eric Pasmant
  • Caroline Silve
  • Nadia Mehsen-Cetre
  • Romain Coriat
  • Alexandre Rouquette
  • Bertrand Douset
  • Frédéric Prat
  • Karen Leroy
  • Medicine (Baltimore).2019 Dec;98(50):e18102. 00005792-201912130-00010. doi: 10.1097/MD.0000000000018102.

NiOドープPtナノ構造体ハイブリッドにより増幅された新しいニッケルベース共結晶錯体電極触媒；セロトニン存在下でのシステアミン定量のための高感度アプローチ

A new nickel-based co-crystal complex electrocatalyst amplified by NiO dope Pt nanostructure hybrid; a highly sensitive approach for determination of cysteamine in the presence of serotonin.
  • Hassan Karimi-Maleh
  • Fatemeh Karimi
  • Yasin Orooji
  • Ghobad Mansouri
  • Amir Razmjou
  • Aysenur Aygun
  • Fatih Sen
  • Sci Rep.2020 Jul;10(1):11699. 10.1038/s41598-020-68663-2. doi: 10.1038/s41598-020-68663-2.Epub 2020-07-16.

中等度および重度の子宮内膜症に対する手術後の生殖能力と再発 - レトロスペクティブな単一施設の分析

Reproductive capacity and recurrence of disease after surgery for moderate and severe endometriosis - a retrospective single center analysis.
  • Cordula Schippert
  • Yvonne Witte
  • Janina Bartels
  • Guillermo-José Garcia-Rocha
  • Matthias Jentschke
  • Peter Hillemanns
  • Sudip Kundu
  • BMC Womens Health.2020 Jul;20(1):144. 10.1186/s12905-020-01016-3. doi: 10.1186/s12905-020-01016-3.Epub 2020-07-13.

PyIR: IgBLASTを用いた数十億の免疫グロブリンやT細胞受容体配列を処理するためのスケーラブルなラッパー

PyIR: a scalable wrapper for processing billions of immunoglobulin and T cell receptor sequences using IgBLAST.
  • Cinque Soto
  • Jessica A Finn
  • Jordan R Willis
  • Samuel B Day
  • Robert S Sinkovits
  • Taylor Jones
  • Samuel Schmitz
  • Jens Meiler
  • Andre Branchizio
  • James E Crowe
  • BMC Bioinformatics.2020 Jul;21(1):314. 10.1186/s12859-020-03649-5. doi: 10.1186/s12859-020-03649-5.Epub 2020-07-16.

原発性骨癌の転移に対するMAPK7/MMP9軸の標的化

Targeting the MAPK7/MMP9 axis for metastasis in primary bone cancer.
  • Darrell Green
  • Heather Eyre
  • Archana Singh
  • Jessica T Taylor
  • Jason Chu
  • Lee Jeys
  • Vaiyapuri Sumathi
  • Aman Coonar
  • Doris Rassl
  • Muhammad Babur
  • Duncan Forster
  • Saba Alzabin
  • Frida Ponthan
  • Adam McMahon
  • Brian Bigger
  • Tristan Reekie
  • Michael Kassiou
  • Kaye Williams
  • Tamas Dalmay
  • William D Fraser
  • Katherine G Finegan
  • Oncogene.2020 Jul;10.1038/s41388-020-1379-0. doi: 10.1038/s41388-020-1379-0.Epub 2020-07-13.

循環腫瘍DNAから検出されたEGFR T790M変異を有する非小細胞肺癌のセカンドライン治療におけるオシメルチニブの第II相試験。LiquidLung-O-Cohort 2

A Phase II Trial of Osimertinib in the Second-Line Treatment of Non-small Cell Lung Cancer with the EGFR T790M Mutation, Detected from Circulating Tumor DNA: LiquidLung-O-Cohort 2.
  • Cheol-Kyu Park
  • Hyun-Ju Cho
  • Yoo-Duk Choi
  • In-Jae Oh
  • Young-Chul Kim
  • Cancer Res Treat.2019 Apr;51(2):777-787. crt.2018.387. doi: 10.4143/crt.2018.387.Epub 2018-09-07.

熱帯環境における機械学習アルゴリズムとリモートセンシングデータを用いた地すべり感受性マッピング

Landslide Susceptibility Mapping Using Machine Learning Algorithms and Remote Sensing Data in a Tropical Environment.
  • Viet-Ha Nhu
  • Ayub Mohammadi
  • Himan Shahabi
  • Baharin Bin Ahmad
  • Nadhir Al-Ansari
  • Ataollah Shirzadi
  • John J Clague
  • Abolfazl Jaafari
  • Wei Chen
  • Hoang Nguyen
  • Int J Environ Res Public Health.2020 Jul;17(14). E4933. doi: 10.3390/ijerph17144933.Epub 2020-07-08.

自己免疫における病原性の手がかりに対する天然物の作用。古典的な治療法と比較した全身性エリテマトーデスおよび関節リウマチにおける有効性

Natural products action on pathogenic cues in autoimmunity: Efficacy in systemic lupus erythematosus and rheumatoid arthritis as compared to classical treatments.
  • Fan Cao
  • Ming-Han Cheng
  • Li-Qin Hu
  • Hui-Hui Shen
  • Jin-Hui Tao
  • Xiao-Mei Li
  • Hai-Feng Pan
  • Jian Gao
  • Pharmacol. Res..2020 Jul;:105054. S1043-6618(20)31362-1. doi: 10.1016/j.phrs.2020.105054.Epub 2020-07-06.

イタリアの猛禽類におけるトキソプラズマ・ゴンドイ感染症。血清疫学と危険因子の解析

Toxoplasma gondii infection in raptors from Italy: Seroepidemiology and risk factors analysis.
  • Alessia Libera Gazzonis
  • Sergio Aurelio Zanzani
  • Azzurra Santoro
  • Fabrizia Veronesi
  • Emanuela Olivieri
  • Luca Villa
  • Emanuele Lubian
  • Silvia Lovati
  • Fulvio Bottura
  • Sara Epis
  • Maria Teresa Manfredi
  • Comp. Immunol. Microbiol. Infect. Dis..2018 Oct;60:42-45. S0147-9571(18)30084-5. doi: 10.1016/j.cimid.2018.10.002.Epub 2018-10-13.

メラトニンは、グリコーゲン合成酵素キナーゼ-3と活性酸素種が関与するヒトSK-MEL-1メラノーマ細胞のメラニン生成を誘導する

Melatonin Induces Melanogenesis in Human SK-MEL-1 Melanoma Cells Involving Glycogen Synthase Kinase-3 and Reactive Oxygen Species.
  • Juan Perdomo
  • Carlos Quintana
  • Ignacio González
  • Inmaculada Hernández
  • Sara Rubio
  • Juan F Loro
  • Russel J Reiter
  • Francisco Estévez
  • José Quintana
  • Int J Mol Sci.2020 Jul;21(14). E4970. doi: 10.3390/ijms21144970.Epub 2020-07-14.

TLR4アゴニストは、心臓寄生虫の負担を減少させることにより、トリパノソーマ・クルジ急性致死感染症から保護します

TLR4 agonist protects against Trypanosoma cruzi acute lethal infection by decreasing cardiac parasite burdens.
  • Liliana E Villanueva-Lizama
  • Julio V Cruz-Chan
  • Leroy Versteeg
  • Christian F Teh-Poot
  • Kristyn Hoffman
  • April Kendricks
  • Brian Keegan
  • Jeroen Pollet
  • Fabian Gusovsky
  • Peter J Hotez
  • Maria Elena Bottazzi
  • Kathryn M Jones
  • Parasite Immunol..2020 Jun;:e12769. doi: 10.1111/pim.12769.Epub 2020-06-26.

アルキル化修復ホモログ8（ALKBH8）は、環境汚染物質ナフタレンからマウスの肺を保護し、耐性を駆動します

The epitranscriptomic writer ALKBH8 drives tolerance and protects mouse lungs from the environmental pollutant naphthalene.
  • Andrea Leonardi
  • Nataliia Kovalchuk
  • Lei Yin
  • Lauren Endres
  • Sara Evke
  • Steven Nevins
  • Samuel Martin
  • Peter C Dedon
  • J Andres Melendez
  • Laura Van Winkle
  • Qing-Yu Zhang
  • Xinxin Ding
  • Thomas J Begley
  • Epigenetics.2020 Apr;:1-18. doi: 10.1080/15592294.2020.1750213.Epub 2020-04-17.

ミオイノシトールホメオスタシスを介した細胞死へのシロイヌナズナBIGタンパク質の関与

Involvement of Arabidopsis BIG protein in cell death mediated by Myo-inositol homeostasis.
  • Quentin Bruggeman
  • Florence Piron-Prunier
  • Frédérique Tellier
  • Jean-Denis Faure
  • David Latrasse
  • Deborah Manza-Mianza
  • Christelle Mazubert
  • Sylvie Citerne
  • Stéphanie Boutet-Mercey
  • Raphael Lugan
  • Catherine Bergounioux
  • Cécile Raynaud
  • Moussa Benhamed
  • Marianne Delarue
  • Sci Rep.2020 Jul;10(1):11268. 10.1038/s41598-020-68235-4. doi: 10.1038/s41598-020-68235-4.Epub 2020-07-09.

ブラジル南東部のイビティポカ州立公園における野鳥の未熟なマダニと新規のリケッチア菌株の分子検出

Immature ticks on wild birds and the molecular detection of a novel Rickettsia strain in the Ibitipoca State Park, southeastern Brazil.
  • Diego G Ramirez
  • Hermes R Luz
  • Sebastián Muñoz-Leal
  • Walter Flausino
  • Igor C L Acosta
  • Thiago F Martins
  • Maristela Peckle
  • Helio F Santos
  • Guilherme P Furusawa
  • Marcelo B Labruna
  • João L H Faccini
  • Exp. Appl. Acarol..2020 Jul;81(3):457-467. 10.1007/s10493-020-00521-2. doi: 10.1007/s10493-020-00521-2.Epub 2020-07-08.

レスベラトロールは、初代培養ニューロンにおけるAMPKシグナル伝達経路を介したベンゾ(a)ピレン誘発性ミトコンドリア恒常性の障害を抑制します

Resveratrol prevents benzo(a)pyrene-induced disruption of mitochondrial homeostasis via the AMPK signaling pathway in primary cultured neurons.
  • Run-Run Kang
  • Qian Sun
  • Kai-Ge Chen
  • Qing-Tian Cao
  • Chang Liu
  • Kuan Liu
  • Zhuo Ma
  • Yu Deng
  • Wei Liu
  • Bin Xu
  • Environ. Pollut..2020 Jun;261:114207. S0269-7491(19)36249-9. doi: 10.1016/j.envpol.2020.114207.Epub 2020-02-20.

陽子線治療を受けた肺がん患者の肺炎に対する光子ベースの正常組織合併症確率モデルの更新

Updating Photon-Based Normal Tissue Complication Probability Models for Pneumonitis in Patients With Lung Cancer Treated With Proton Beam Therapy.
  • Varsha Jain
  • Anne G H Niezink
  • Melissa Frick
  • Abigail Doucette
  • Amberly Mendes
  • Charles B Simone
  • Johannes A Langendijk
  • Robin Wijsman
  • Steven J Feigenberg
  • William Levin
  • Keith A Cengel
  • Arjen van der Schaaf
  • Abigail T Berman
  • Pract Radiat Oncol.2020 May;S1879-8500(20)30102-8. doi: 10.1016/j.prro.2020.04.005.Epub 2020-05-13.

4-アルキル-1,4-ジヒドロピリジンとチオスルホネートまたはセレンスルホネートとの可視光促進クロスカップリング反応。スルフィド、セレン化物、スルホキシドへの統一的なアプローチ

Visible-Light-Promoted Cross-Coupling Reactions of 4-Alkyl-1,4-dihydropyridines with Thiosulfonate or Selenium Sulfonate: A Unified Approach to Sulfides, Selenides, and Sulfoxides.
  • Jian Li
  • Xin-Er Yang
  • Shan-Le Wang
  • Long-Long Zhang
  • Xiao-Zhou Zhou
  • Shun-Yi Wang
  • Shun-Jun Ji
  • Org. Lett..2020 Jun;22(12):4908-4913. doi: 10.1021/acs.orglett.0c01776.Epub 2020-06-10.

経口避妊薬を服用している健康な成人女性における月経周期の日によって、便の頻度や形態、胃腸症状が異なる：前向き観察研究

Stool frequency and form and gastrointestinal symptoms differ by day of the menstrual cycle in healthy adult women taking oral contraceptives: a prospective observational study.
  • Taylor C Judkins
  • Jennifer C Dennis-Wall
  • Shireen Madani Sims
  • James Colee
  • Bobbi Langkamp-Henken
  • BMC Womens Health.2020 Jun;20(1):136. 10.1186/s12905-020-01000-x. doi: 10.1186/s12905-020-01000-x.Epub 2020-06-29.

統合失調症の薬理学的治療中に発症した頸部のねじり性ジストニアと小脳運動失調を伴う著しい小脳萎縮を伴うジストニアを疑った1例

[A case suspected of dystonia with marked cerebellar atrophy with torsion dystonia of the neck and cerebellar ataxia that developed during pharmacologic schizophrenia treatment].
  • Yumi Hoshino
  • Masashi Yamazaki
  • Yusuke Mochizuki
  • Hideo Makishita
  • Kunihiro Yoshida
  • Rinsho Shinkeigaku.2020 Jul;doi: 10.5692/clinicalneurol.60.cn-001395.Epub 2020-07-07.

ベンゾアピレンの曝露は、雌のホタテ貝柱Chlamys farreriにおいて、ステロイド生成経路とエストロゲンシグナル伝達経路を介して生殖内分泌かく乱作用を誘導した

Benzo[a]pyrene exposure induced reproductive endocrine-disrupting effects via the steroidogenic pathway and estrogen signaling pathway in female scallop Chlamys farreri.
  • Yingying Yang
  • Yueyao Zhou
  • Luqing Pan
  • Ruiyi Xu
  • Dongyu Li
  • Sci. Total Environ..2020 Jul;726:138585. S0048-9697(20)32101-X. doi: 10.1016/j.scitotenv.2020.138585.Epub 2020-04-08.

組換えバキュロウイルスから発現したThyrinteina arnobia cypovirusポリヘドリンの細胞ライン依存性結晶形態と局在化の研究

Cell-line-dependent crystal morphology and sublocalization of the Thyrinteina arnobia cypovirus polyhedrin expressed from a recombinant baculovirus.
  • Leonardo A Silva
  • Daniel M P Ardisson-Araújo
  • Fabricio S Morgado
  • André B Horta
  • Manoel Victor Franco Lemos
  • Carlos F Wilcken
  • Bergmann M Ribeiro
  • Arch. Virol..2019 Jun;164(6):1677-1682. 10.1007/s00705-019-04214-z. doi: 10.1007/s00705-019-04214-z.Epub 2019-04-06.

インフルエンザA H5N1ウイルス誘発性肺障害の再利用薬としてアミトリプチリン塩酸塩、フラビンアデニンジヌクレオチド、アザシチジン、カルシトリオールを同定した

Identification of amitriptyline HCl, flavin adenine dinucleotide, azacitidine and calcitriol as repurposing drugs for influenza A H5N1 virus-induced lung injury.
  • Fengming Huang
  • Cong Zhang
  • Qiang Liu
  • Yan Zhao
  • Yuqing Zhang
  • Yuhao Qin
  • Xiao Li
  • Chang Li
  • Congzhao Zhou
  • Ningyi Jin
  • Chengyu Jiang
  • PLoS Pathog..2020 03;16(3):e1008341. PPATHOGENS-D-19-02141. doi: 10.1371/journal.ppat.1008341.Epub 2020-03-16.

Mill., Mill.およびL.のEU域外のウイルスおよびビロイドの有害生物分類

Pest categorisation of non-EU viruses and viroids of Mill., Mill. and L.
  • Claude Bragard
  • Katharina Dehnen-Schmutz
  • Paolo Gonthier
  • Marie-Agnès Jacques
  • Josep Anton Jaques Miret
  • Annemarie Fejer Justesen
  • Alan MacLeod
  • Christer Sven Magnusson
  • Panagiotis Milonas
  • Juan A Navas-Cortes
  • Stephen Parnell
  • Roel Potting
  • Philippe Lucien Reignault
  • Hans-Hermann Thulke
  • Wopke Van der Werf
  • Antonio Vicent Civera
  • Jonathan Yuen
  • Lucia Zappalà
  • Thierry Candresse
  • Elisavet Chatzivassiliou
  • Franco Finelli
  • Stephan Winter
  • Michela Chiumenti
  • Francesco Di Serio
  • Tomasz Kaluski
  • Angelantonio Minafra
  • Luisa Rubino
  • EFSA J.2019 Sep;17(9):e05590. EFS25590. doi: 10.2903/j.efsa.2019.5590.Epub 2019-09-30.

可溶性ウロキナーゼプラスミノーゲンアクチベーター受容体の急性冠症候群における長期予後バイオマーカーとしての検討

Soluble urokinase plasminogen activator receptor as a long-term prognostic biomarker in acute coronary syndromes.
  • Óscar Manuel Peiró
  • German Cediel
  • Gil Bonet
  • Sergio Rojas
  • Verónica Quintern
  • Anna Carrasquer
  • Maribel González-Del-Hoyo
  • Esther Sanz
  • Alfredo Bardají
  • Biomarkers.2020 Jul;25(5):402-409. doi: 10.1080/1354750X.2020.1778090.Epub 2020-06-18.

アブサイシン酸の葉面散布はカドミウムストレスを緩和し、カドミウム感受性レタス( L.)の遺伝子型の栄養品質と食品安全性を向上させることがわかった

Foliar application of abscisic acid mitigates cadmium stress and increases food safety of cadmium-sensitive lettuce ( L.) genotype.
  • Mohammed Mujitaba Dawuda
  • Weibiao Liao
  • Linli Hu
  • Jihua Yu
  • Jianming Xie
  • Alejandro Calderón-Urrea
  • Yue Wu
  • Zhongqi Tang
  • PeerJ.2020;8:e9270. 9270. doi: 10.7717/peerj.9270.Epub 2020-07-02.

ウイルスに感染したアブラムシの耐熱性の向上は、ニッチの拡大と種間競争の減少をもたらします

Enhanced heat tolerance of viral-infected aphids leads to niche expansion and reduced interspecific competition.
  • Mitzy F Porras
  • Carlos A Navas
  • James H Marden
  • Mark C Mescher
  • Consuelo M De Moraes
  • Sylvain Pincebourde
  • Andrés Sandoval-Mojica
  • Juan A Raygoza-Garay
  • German A Holguin
  • Edwin G Rajotte
  • Tomás A Carlo
  • Nat Commun.2020 03;11(1):1184. 10.1038/s41467-020-14953-2. doi: 10.1038/s41467-020-14953-2.Epub 2020-03-04.

マイクロプラスチックに吸着した有機汚染物質がメダカの初期生育に影響を与える

Organic contaminants sorbed to microplastics affect marine medaka fish early life stages development.
  • Florane Le Bihanic
  • Christelle Clérandeau
  • Bettie Cormier
  • Jean-Claude Crebassa
  • Steffen H Keiter
  • Ricardo Beiras
  • Bénédicte Morin
  • Marie-Laure Bégout
  • Xavier Cousin
  • Jérôme Cachot
  • Mar. Pollut. Bull..2020 May;154:111059. S0025-326X(20)30177-6. doi: 10.1016/j.marpolbul.2020.111059.Epub 2020-03-31.

炎症から皮膚修復へ。ルピオールの局所適用は、サイトカインレベル、NF-κB、Ki-67、成長因子の発現、およびコラーゲン線維の分布を調節することにより、ラットの皮膚創傷治癒を改善します

From Inflammation to Cutaneous Repair: Topical Application of Lupeol Improves Skin Wound Healing in Rats by Modulating the Cytokine Levels, NF-κB, Ki-67, Growth Factor Expression, and Distribution of Collagen Fibers.
  • Fernando Pereira Beserra
  • Lucas Fernando Sérgio Gushiken
  • Ana Júlia Vieira
  • Danilo Augusto Bérgamo
  • Patrícia Luísa Bérgamo
  • Mariana Oliveira de Souza
  • Carlos Alberto Hussni
  • Regina Kiomi Takahira
  • Rafael Henrique Nóbrega
  • Emanuel Ricardo Monteiro Martinez
  • Christopher John Jackson
  • Gabriela Lemos de Azevedo Maia
  • Ariane Leite Rozza
  • Cláudia Helena Pellizzon
  • Int J Mol Sci.2020 Jul;21(14). E4952. doi: 10.3390/ijms21144952.Epub 2020-07-13.

免疫チェックポイント阻害薬を用いたがん領域の臨床試験で使用された患者報告アウトカム指標：システマティックレビュー

Patient-reported outcome instruments used in immune-checkpoint inhibitor clinical trials in oncology: a systematic review.
  • Sara Colomer-Lahiguera
  • Denise Bryant-Lukosius
  • Sarah Rietkoetter
  • Lorraine Martelli
  • Karin Ribi
  • Donna Fitzpatrick-Lewis
  • Diana Sherifali
  • Angela Orcurto
  • Rosalyn Juergens
  • Manuela Eicher
  • J Patient Rep Outcomes.2020 Jul;4(1):58. 10.1186/s41687-020-00210-z. doi: 10.1186/s41687-020-00210-z.Epub 2020-07-16.

ランゲルハンスの全臓器および膵島の放射線標識されたエクセンジンを用いたイメージングによる吸収線量計算のための全臓器および膵島線量推定法

Whole organ and islet of Langerhans dosimetry for calculation of absorbed doses resulting from imaging with radiolabeled exendin.
  • Inge van der Kroon
  • Wietske Woliner-van der Weg
  • Maarten Brom
  • Lieke Joosten
  • Cathelijne Frielink
  • Mark W Konijnenberg
  • Eric P Visser
  • Martin Gotthardt
  • Sci Rep.2017 01;7:39800. srep39800. doi: 10.1038/srep39800.Epub 2017-01-09.

低用量メトホルミンはヒト食道癌における腫瘍免疫微小環境を再プログラムする。第Ⅱ相臨床試験の結果

Low-dose metformin reprograms the tumor immune microenvironment in human esophageal cancer: Results of a phase II clinical trial.
  • Shuhong Wang
  • Yusheng Lin
  • Xiao Xiong
  • Lu Wang
  • Yi Guo
  • Yuping Chen
  • Shaobin Chen
  • Geng Wang
  • Peng Lin
  • Hongcai Chen
  • Sai-Ching J Yeung
  • Edwin Bremer
  • Hao Zhang
  • Clin. Cancer Res..2020 Jul;clincanres.0113.2020. doi: 10.1158/1078-0432.CCR-20-0113.Epub 2020-07-09.

オーストラリアのハンターバレーとマニングバレー地域における一過性脳虚血発作と軽度脳卒中の可能性のある患者の特徴（INSIST研究）

The Characteristics of Patients With Possible Transient Ischemic Attack and Minor Stroke in the Hunter and Manning Valley Regions, Australia (the INSIST Study).
  • Shinya Tomari
  • Parker Magin
  • Daniel Lasserson
  • Debbie Quain
  • Jose M Valderas
  • Helen M Dewey
  • P Alan Barber
  • Neil J Spratt
  • Dominique A Cadilhac
  • Valery L Feigin
  • Peter M Rothwell
  • Hossein Zareie
  • Carlos Garcia-Esperon
  • Andrew Davey
  • Nashwa Najib
  • Milton Sales
  • Christopher R Levi
  • Front Neurol.2020;11:383. doi: 10.3389/fneur.2020.00383.Epub 2020-05-15.

ゼブラフィッシュ（Danio rerio）の長期摂取における異なるサイズのマイクロプラスチック粒子の潜在的な影響の組織学的、酵素学的、化学的分析

Histological, enzymatic and chemical analyses of the potential effects of differently sized microplastic particles upon long-term ingestion in zebrafish (Danio rerio).
  • Annika Batel
  • Lisa Baumann
  • Camilla Catarci Carteny
  • Bettie Cormier
  • Steffen H Keiter
  • Thomas Braunbeck
  • Mar. Pollut. Bull..2020 Apr;153:111022. S0025-326X(20)30140-5. doi: 10.1016/j.marpolbul.2020.111022.Epub 2020-02-29.

オクトコアのゲノム配列 - 地中海における気候変動の影響を研究するための重要な資料

The Genome Sequence of the Octocoral - A Key Resource To Study the Impact of Climate Change in the Mediterranean.
  • Jean-Baptiste Ledoux
  • Fernando Cruz
  • Jèssica Gómez-Garrido
  • Regina Antoni
  • Julie Blanc
  • Daniel Gómez-Gras
  • Silvija Kipson
  • Paula López-Sendino
  • Agostinho Antunes
  • Cristina Linares
  • Marta Gut
  • Tyler S Alioto
  • Joaquim Garrabou
  • G3 (Bethesda).2020 Jul;g3.401371.2020. doi: 10.1534/g3.120.401371.Epub 2020-07-13.

メラトニンは、マウス肝臓におけるMir-34a/Sirt1/オートファジー経路の活性化を介してベンゾピレン誘導アポトーシスを抑制する

Melatonin inhibits Benzo(a)pyrene-Induced apoptosis through activation of the Mir-34a/Sirt1/autophagy pathway in mouse liver.
  • Samira Barangi
  • Soghra Mehri
  • Zahra Moosavi
  • A Wallace Hayesd
  • Russel J Reiter
  • Daniel P Cardinali
  • Gholamreza Karimi
  • Ecotoxicol. Environ. Saf..2020 Jun;196:110556. S0147-6513(20)30395-X. doi: 10.1016/j.ecoenv.2020.110556.Epub 2020-04-02.

第35回外科学会学術集会報告書。実験的外科手術に焦点を当てた発表、ラボ、ワークショップの概要、クリアウォータービーチ、フロリダ州、2019年9月25-27日

Meeting Report of the 35th Annual Meeting of the Academy of Surgical Research: Summary of Presentations, Labs, and Workshops, Focusing on Experimental Surgery, Clearwater Beach, FL, 25-27 September 2019.
  • Melanie L Graham
  • Jenifer Sweet
  • Jennifer Sheehan
  • J Invest Surg.2020 Jun;:1-8. doi: 10.1080/08941939.2020.1782543.Epub 2020-06-22.

また、PKD2/ポリシスティン-2はBECN1と複合体を形成することでオートファジーを誘導することを明らかにした

PKD2/polycystin-2 induces autophagy by forming a complex with BECN1.
  • Daniel Peña-Oyarzun
  • Marcelo Rodriguez-Peña
  • Francesca Burgos-Bravo
  • Angelo Vergara
  • Catalina Kretschmar
  • Cristian Sotomayor-Flores
  • Cesar A Ramirez-Sarmiento
  • Humbert De Smedt
  • Montserrat Reyes
  • William Perez
  • Vicente A Torres
  • Eugenia Morselli
  • Francisco Altamirano
  • Christian A M Wilson
  • Joseph A Hill
  • Sergio Lavandero
  • Alfredo Criollo
  • Autophagy.2020 Jun;:1-15. doi: 10.1080/15548627.2020.1782035.Epub 2020-06-30.

直腸癌における磁気共鳴画像を用いた局所領域の病期分類：診断精度における拡散強調画像の影響

Locoregional staging using magnetic resonance imaging in rectal cancer: influence of diffusion-weighted imaging in the diagnostic accuracy.
  • Roberto Fornell-Pérez
  • Patricia Alemán-Flores
  • Gabriela Porcel-de Peralta
  • Jano Rubio-García
  • María C González-Domínguez
  • Joel Aranda-Sánchez
  • Valentina Vivas-Escalona
  • Juan F Loro-Ferrer
  • Cir Cir.2020;88(4):420-427. j88/4/420. doi: 10.24875/CIRU.20001719.

非ステロイド性抗炎症薬の探索的ゲノムワイド相互作用解析と大腸がんリスクの予測遺伝子発現

Exploratory genome-wide interaction analysis of non-steroidal anti-inflammatory drugs and predicted gene expression on colorectal cancer risk.
  • Xiaoliang Wang
  • Yu-Ru Su
  • Paneen S Petersen
  • Stephanie Bien
  • Stephanie L Schmit
  • David A Drew
  • Demetrius Albanes
  • Sonja I Berndt
  • Hermann Brenner
  • Peter T Campbell
  • Graham Casey
  • Jenny Cheng-Claude
  • Steven Gallinger
  • Stephen B Gruber
  • Robert W Haile
  • Tabitha A Harrison
  • Michael Hoffmeister
  • Eric J Jacobs
  • Mark A Jenkins
  • Amit D Joshi
  • Li Li
  • Yi Lin
  • Noralane M Lindor
  • Loic Le Marchand
  • Vicente Martín
  • Roger L Milne
  • Robert Maclnnis
  • Victor Moreno
  • Hongmei Nan
  • Polly A Newcomb
  • John D Potter
  • Gad Rennert
  • Hedy S Rennert
  • Martha L Slattery
  • Stephen N Thibodeau
  • Stephanie J Weinstein
  • Michael O Woods
  • Andrew T Chan
  • Emily White
  • Li Hsu
  • Ulrike Peters
  • Cancer Epidemiol. Biomarkers Prev..2020 Jul;cebp.1018.2019. doi: 10.1158/1055-9965.EPI-19-1018.Epub 2020-07-10.

再発性尿管卵管接合部閉塞に対する管理としてのロボット支援腹腔鏡下膿皮形成術：一次膿皮形成術との比較研究

Robotic-assisted laparoscopic pyeloplasty as management for recurrent ureteropelvic junction obstruction: a comparison study with primary pyeloplasty.
  • Peng Zhang
  • Taoping Shi
  • Xenginn Fam
  • Liangyou Gu
  • Yundong Xuan
  • Luojia Yang
  • Baojun Wang
  • Xing Ai
  • Zhuomin Jia
  • Hongzhao Li
  • Xu Zhang
  • Xin Ma
  • Transl Androl Urol.2020 Jun;9(3):1278-1285. tau-09-03-1278. doi: 10.21037/tau.2020.03.25.

ヒスポロンによるリポ多糖類誘発性急性肺障害の軽減、TLR4/PI3K/Akt/mTORおよびKeap1/Nrf2/HO-1経路の制御、および酸化ストレス媒介のERストレス誘発性アポトーシスおよびオートファジーの抑制を介して

Attenuation of Lipopolysaccharide-Induced Acute Lung Injury by Hispolon in Mice, Through Regulating the TLR4/PI3K/Akt/mTOR and Keap1/Nrf2/HO-1 Pathways, and Suppressing Oxidative Stress-Mediated ER Stress-Induced Apoptosis and Autophagy.
  • Ching-Ying Huang
  • Jeng-Shyan Deng
  • Wen-Chin Huang
  • Wen-Ping Jiang
  • Guan-Jhong Huang
  • Nutrients.2020 Jun;12(6). E1742. doi: 10.3390/nu12061742.Epub 2020-06-10.

がん転帰は解剖学的に切除可能な膵管腺癌における術前CA 19-9とは独立している：レトロスペクティブコホート解析

Cancer outcomes are independent of preoperative CA 19-9 in anatomically resectable pancreatic ductal adenocarcinoma: A retrospective cohort analysis.
  • Joon Kyung Kim
  • Danielle K DePeralta
  • Takuya Ogami
  • Jason W Denbo
  • Jose Pimiento
  • Pamela J Hodul
  • Mokenge P Malafa
  • Dae W Kim
  • Jason B Fleming
  • Benjamin D Powers
  • J Surg Oncol.2020 Jul;doi: 10.1002/jso.26103.Epub 2020-07-16.

ヨルダンの酸性スフィンゴミエリン酵素欠損症（ニーマンピックA型およびB型）児におけるSMPD1遺伝子の新規変異．

Novel mutations in the SMPD1 gene in Jordanian children with Acid sphingomyelinase deficiency (Niemann-Pick types A and B).
  • Laith Al-Eitan
  • Kifah Alqa'qa'
  • Wajdi Amayreh
  • Hanan Aljamal
  • Rame Khasawneh
  • Batool Al-Zoubi
  • Israa Okour
  • Amany Haddad
  • Yazan Haddad
  • Hazem Haddad
  • Gene.2020 Jul;747:144683. S0378-1119(20)30352-8. doi: 10.1016/j.gene.2020.144683.Epub 2020-04-18.

Extended-spectrum β-lactamase-producing Enterobacteralesの同定のための臨床予測ルールの独立した外部検証、バーゼル大学病院、スイス、2010年1月～2016年12月

Independent, external validation of clinical prediction rules for the identification of extended-spectrum β-lactamase-producing Enterobacterales, University Hospital Basel, Switzerland, January 2010 to December 2016.
  • Isabelle Vock
  • Lisandra Aguilar-Bultet
  • Adrian Egli
  • Pranita D Tamma
  • Sarah Tschudin-Sutter
  • Euro Surveill..2020 Jul;25(26). doi: 10.2807/1560-7917.ES.2020.25.26.1900317.

ゼラチンをポリビニルアルコールヒドロゲル上にワンポットで共有結合的にグラフトすることで、血管内皮化と血液適合性を向上させ、合成血管グラフトの応用を可能にしました

One-Pot Covalent Grafting of Gelatin on Poly(Vinyl Alcohol) Hydrogel to Enhance Endothelialization and Hemocompatibility for Synthetic Vascular Graft Applications.
  • Muhammad Rizwan
  • Yuan Yao
  • Maud B Gorbet
  • John Tse
  • Deirdre E J Anderson
  • Monica T Hinds
  • Evelyn K F Yim
  • ACS Appl Bio Mater.2020 Jan;3(1):693-703. doi: 10.1021/acsabm.9b01026.Epub 2019-11-19.

ストレプトゾトシン誘発糖尿病ラットにおけるアキレス腱の初期リモデリングに対する光生体調節と運動の効果

Effect of photobiomodulation and exercise on early remodeling of the Achilles tendon in streptozotocin-induced diabetic rats.
  • Anderson Rodrigues de Oliveira
  • Flávio Santos da Silva
  • Raul Hernandes Bortolin
  • Dáfiny Emanuele da Silva Marques
  • Gracielle Vieira Ramos
  • Rita C Marqueti
  • Naisandra Bezerra da Silva
  • Karina Carla de Paula Medeiros
  • Márcio Assolin Corrêa
  • João Paulo Matos Santos Lima
  • Adriana Augusto de Rezende
  • Paul W Ackermann
  • Bento J Abreu
  • Wouber Hérickson de Brito Vieira
  • PLoS ONE.2019;14(2):e0211643. PONE-D-18-29338. doi: 10.1371/journal.pone.0211643.Epub 2019-02-04.

トランスクリプトーム解析により、Cucumis sativus L.のFusarium oxysporum f. sp. cucumerinum感染に対するエチレンを媒介とした防御反応が明らかになった

Transcriptome analysis reveals ethylene-mediated defense responses to Fusarium oxysporum f. sp. cucumerinum infection in Cucumis sativus L.
  • Jingping Dong
  • Yuean Wang
  • Qianqian Xian
  • Xuehao Chen
  • Jun Xu
  • BMC Plant Biol..2020 Jul;20(1):334. 10.1186/s12870-020-02537-7. doi: 10.1186/s12870-020-02537-7.Epub 2020-07-16.

4-クロロ-2-ニトロ安息香酸と4-hy-droxy-キノリンの結晶構造：4-クロロ-2-ニトロ安息香酸-キノリン-4(1)-オン(1/1)と4-hy-droxy-キノリニウム-4-クロロ-2-ニトロ安息香酸の2つの状態にわたる無秩序構造

Crystal structure of 4-chloro-2-nitro-benzoic acid with 4-hy-droxy-quinoline: a disordered structure over two states of 4-chloro-2-nitro-benzoic acid-quinolin-4(1)-one (1/1) and 4-hy-droxy-quinolinium 4-chloro-2-nitro-benzoate.
  • Kazuma Gotoh
  • Hiroyuki Ishida
  • Acta Crystallogr E Crystallogr Commun.2019 Dec;75(Pt 12):1853-1856. lh5935. doi: 10.1107/S205698901901497X.Epub 2019-11-08.

アリゾナ州とニューメキシコ州におけるAmblyomma maculatum sensu lato（アカリ：イクソ科）とRickettsia parkeri（リケッチアレス：リケッチアセア科）の分布と発生状況、2017-2019年

Distribution and Occurrence of Amblyomma maculatum sensu lato (Acari: Ixodidae) and Rickettsia parkeri (Rickettsiales: Rickettsiaceae), Arizona and New Mexico, 2017-2019.
  • Joy A Hecht
  • Michelle E J Allerdice
  • Sandor E Karpathy
  • Hayley D Yaglom
  • Mariana Casal
  • R Ryan Lash
  • Jesus Delgado-de la Mora
  • Jesus D Licona-Enriquez
  • David Delgado-de la Mora
  • Kathleen Groschupf
  • James W Mertins
  • Amanda Moors
  • Don E Swann
  • Christopher D Paddock
  • J. Med. Entomol..2020 Jul;tjaa130. doi: 10.1093/jme/tjaa130.Epub 2020-07-10.

プロサバイバルキナーゼのミトコンドリア内局在の違いとDUSP5とPHLPP-1による機能制御

Distinct intra-mitochondrial localizations of pro-survival kinases and regulation of their functions by DUSP5 and PHLPP-1.
  • Wataru Ohwada
  • Masaya Tanno
  • Toshiyuki Yano
  • Sang-Bing Ong
  • Koki Abe
  • Tatsuya Sato
  • Atsushi Kuno
  • Takayuki Miki
  • Hirohito Sugawara
  • Yusuke Igaki
  • Tetsuji Miura
  • Biochim Biophys Acta Mol Basis Dis.2020 May;1866(10):165851. S0925-4439(20)30198-8. doi: 10.1016/j.bbadis.2020.165851.Epub 2020-05-30.

血球内で測定されたDNA損傷は、生殖細胞腫瘍患者の全生存率と無増悪生存率を予測する

DNA damage measured in blood cells predicts overall and progression-free survival in germ cell tumour patients.
  • Zuzana Sestakova
  • Katarina Kalavska
  • Bozena Smolkova
  • Vera Miskovska
  • Katarina Rejlekova
  • Zuzana Sycova-Mila
  • Patrik Palacka
  • Jana Obertova
  • Andrea Holickova
  • Lenka Hurbanova
  • Dana Jurkovicova
  • Jan Roska
  • Eduard Goffa
  • Daniela Svetlovska
  • Michal Chovanec
  • Jozef Mardiak
  • Michal Mego
  • Miroslav Chovanec
  • Mutat. Res..2020 Jun - Jul;854-855:503200. S1383-5718(20)30070-X. doi: 10.1016/j.mrgentox.2020.503200.Epub 2020-05-23.

ウシウイルス性下痢ウイルス 2 型（BVDV）に持続的に感染した単一の大規模商業牛群のホルスタイン未経産牛と牛の二次臨床疾患、乳生産と品質、繁殖への影響の評価

An Assessment of Secondary Clinical Disease, Milk Production and Quality, and the Impact on Reproduction in Holstein Heifers and Cows from a Single Large Commercial Herd Persistently Infected with Bovine Viral Diarrhea Virus Type 2.
  • Natália Sobreira Basqueira
  • Jean Silva Ramos
  • Fabricio Dias Torres
  • Liria Hiromi Okuda
  • David John Hurley
  • Christopher C L Chase
  • Anny Raissa Carolini Gomes
  • Viviani Gomes
  • Viruses.2020 Jul;12(7). E760. doi: 10.3390/v12070760.Epub 2020-07-15.

ラットにおけるCRISPR媒介一塩基多型モデリングは、地中海の変異体に関連付けられている減少した心血管系リスクへの洞察を明らかにする

CRISPR-Mediated Single Nucleotide Polymorphism Modeling in Rats Reveals Insight Into Reduced Cardiovascular Risk Associated With Mediterranean Variant.
  • Atsushi Kitagawa
  • Igor Kizub
  • Christina Jacob
  • Kevin Michael
  • Angelo D'Alessandro
  • Julie A Reisz
  • Michael Grzybowski
  • Aron M Geurts
  • Petra Rocic
  • Rakhee Gupte
  • Joseph M Miano
  • Sachin A Gupte
  • Hypertension.2020 Aug;76(2):523-532. doi: 10.1161/HYPERTENSIONAHA.120.14772.Epub 2020-06-08.

ミオシンVIを欠失した筋芽細胞による異常筋管形成は、細胞骨格組織の変化、筋芽細胞の接着、融合に関連している

Formation of Aberrant Myotubes by Myoblasts Lacking Myosin VI Is Associated with Alterations in the Cytoskeleton Organization, Myoblast Adhesion and Fusion.
  • Lilya Lehka
  • Małgorzata Topolewska
  • Dominika Wojton
  • Olena Karatsai
  • Paloma Alvarez-Suarez
  • Paweł Pomorski
  • Maria Jolanta Rędowicz
  • Cells.2020 Jul;9(7). E1673. doi: 10.3390/cells9071673.Epub 2020-07-11.

アルギニンをベースとしたカチオン性脂質からなるsiRNAの生体適合性ナノベクターを用いたがん細胞の遺伝子ノックダウンへの応用

Biocompatible Nanovector of siRNA Consisting of Arginine-Based Cationic Lipid for Gene Knockdown in Cancer Cells.
  • Natalia Sánchez-Arribas
  • María Martínez-Negro
  • Eva Villar-Álvarez
  • Lourdes Pérez
  • Emilio Aicart
  • Pablo Taboada
  • Andrés Guerrero-Martínez
  • Elena Junquera
  • ACS Appl Mater Interfaces.2020 Jul;doi: 10.1021/acsami.0c06273.Epub 2020-07-13.

Charm IIを用いて牛肉組織中のテトラサイクリンとストレプトマイシンを検出し，関連する耐性菌の分離とガンマ線による耐性制御を行った．

Detection of tetracycline and streptomycin in beef tissues using Charm II, isolation of relevant resistant bacteria and control their resistance by gamma radiation.
  • Eman Araby
  • Hanady G Nada
  • Salwa A Abou El-Nour
  • Ali Hammad
  • BMC Microbiol..2020 Jun;20(1):186. 10.1186/s12866-020-01868-7. doi: 10.1186/s12866-020-01868-7.Epub 2020-06-29.

ヒストンアセチルトランスフェラーゼGcn5は、ヒストンメチルトランスフェラーゼSET1の転写を促進することで遺伝子発現を制御している

Histone acetyltransferase Gcn5 regulates gene expression by promoting the transcription of histone methyltransferase SET1.
  • Xuanyunjing Gong
  • Qi Yu
  • Kai Duan
  • Yue Tong
  • Xinyu Zhang
  • Qianyun Mei
  • Li Lu
  • Xilan Yu
  • Shanshan Li
  • Biochim Biophys Acta Gene Regul Mech.2020 Jul;:194603. S1874-9399(20)30186-3. doi: 10.1016/j.bbagrm.2020.194603.Epub 2020-07-11.

原生動物由来の融合TvG6PD::6PGLタンパク質の特徴と酵素の安定性に及ぼすNADP分子の影響

Characterizing the Fused TvG6PD::6PGL Protein from the Protozoan , and Effects of the NADP Molecule on Enzyme Stability.
  • Laura Morales-Luna
  • Beatriz Hernández-Ochoa
  • Edson Jiovany Ramírez-Nava
  • Víctor Martínez-Rosas
  • Paulina Ortiz-Ramírez
  • Fabiola Fernández-Rosario
  • Abigail González-Valdez
  • Noemí Cárdenas-Rodríguez
  • Hugo Serrano-Posada
  • Sara Centeno-Leija
  • Roberto Arreguin-Espinosa
  • Miguel Cuevas-Cruz
  • Daniel Ortega-Cuellar
  • Verónica Pérez de la Cruz
  • Luz María Rocha-Ramírez
  • Edgar Sierra-Palacios
  • Rosa Angélica Castillo-Rodríguez
  • Vanesa Vega-García
  • Yadira Rufino-González
  • Jaime Marcial-Quino
  • Saúl Gómez-Manzo
  • Int J Mol Sci.2020 Jul;21(14). E4831. doi: 10.3390/ijms21144831.Epub 2020-07-08.

ナチュラルキラー細胞を拡張・活性化したナチュラルキラー細胞は、異なる腫瘍細胞に対して高い抗腫瘍活性を示す

Natural Killer Cells Expanded and Preactivated Exhibit Enhanced Antitumor Activity against Different Tumor Cells in Vitro.
  • Biplob Kumar Biswas
  • Sameer Ahmad Guru
  • Mamta Pervin Sumi
  • Elvia Jamatia
  • Rohit Kumar Gupta
  • Pramod Lali
  • Bidhan Chandra Konar
  • Alpana Saxena
  • Rashid Mir
  • Asian Pac. J. Cancer Prev..2020 Jun;21(6):1595-1605. 89143. doi: 10.31557/APJCP.2020.21.6.1595.Epub 2020-06-01.

フェニルプロパノイド経路の変化は、ポプラの菌根共生能力と根節線虫の感受性に影響を与えている

Alterations in the phenylpropanoid pathway affect poplar ability for ectomycorrhizal colonisation and susceptibility to root-knot nematodes.
  • Marc Behr
  • Fabien Baldacci-Cresp
  • Annegret Kohler
  • Kris Morreel
  • Geert Goeminne
  • Rebecca Van Acker
  • Claire Veneault-Fourrey
  • Adeline Mol
  • Gilles Pilate
  • Wout Boerjan
  • Janice de Almeida Engler
  • Mondher El Jaziri
  • Marie Baucher
  • Mycorrhiza.2020 Jul;10.1007/s00572-020-00976-6. doi: 10.1007/s00572-020-00976-6.Epub 2020-07-09.

イソリキリチゲニンは、MRC-5 細胞において、PI3K/AKT/mTOR 経路を介してオートファジーを活性化し、TGF-β1 誘導性線維芽細胞の増殖を抑制することが知られています

Isoliquiritigenin inhibits TGF-β1-induced fibrogenesis through activating autophagy via PI3K/AKT/mTOR pathway in MRC-5 cells.
  • Jinjuan He
  • Hao Peng
  • Meifang Wang
  • Ying Liu
  • Xingrong Guo
  • Bin Wang
  • Longjun Dai
  • Xueqin Cheng
  • Zhongji Meng
  • Leyong Yuan
  • Fenglin Cai
  • Yijun Tang
  • Acta Biochim. Biophys. Sin. (Shanghai).2020 Jul;gmaa067. doi: 10.1093/abbs/gmaa067.Epub 2020-07-08.

初期変形性関節症の羊モデルにおける異なる細胞ベースの治療後の軟骨バイオメカニクスと膝関節微小環境の評価

Evaluation of cartilage biomechanics and knee joint microenvironment after different cell-based treatments in a sheep model of early osteoarthritis.
  • Francesca Veronesi
  • Matteo Berni
  • Gregorio Marchiori
  • Giorgio Cassiolas
  • Aurelio Muttini
  • Barbara Barboni
  • Lucia Martini
  • Milena Fini
  • Nicola Francesco Lopomo
  • Maurilio Marcacci
  • Elizaveta Kon
  • Int Orthop.2020 Jul;10.1007/s00264-020-04701-y. doi: 10.1007/s00264-020-04701-y.Epub 2020-07-14.

小児の毛細血管性副鼻腔疾患に対する小児内視鏡的毛細血管性副鼻腔治療（PEPSiT）。ヒントとコツと新しい構造化されたプロトコル

Pediatric Endoscopic Pilonidal Sinus Treatment (PEPSiT) in Children With Pilonidal Sinus Disease: Tips and Tricks and New Structurated Protocol.
  • Ciro Esposito
  • Mario Mendoza-Sagaon
  • Fulvia Del Conte
  • Mariapina Cerulo
  • Vincenzo Coppola
  • Giovanni Esposito
  • Giuseppe Cortese
  • Felice Crocetto
  • Ernesto Montaruli
  • Maria Escolino
  • Front Pediatr.2020;8:345. doi: 10.3389/fped.2020.00345.Epub 2020-06-24.

米国外傷外科学会の腎グレード分類システム。分節状腎梗塞はグレードIVの傷害として分類すべきか？

The American Association for the Surgery of Trauma Renal Grading System: Should Segmental Kidney Infarction be Classified as a Grade IV Injury?
  • Sorena Keihani
  • Joel A Gross
  • Ryan P Joyce
  • Sherry S Wang
  • Douglas Rogers
  • Elisa Fang
  • Judith C Hagedorn
  • Bryan Voelzke
  • Alexander P Nocera
  • J Patrick Selph
  • Michael E Rezaee
  • Rachel A Moses
  • Chirag S Arya
  • Rachel L Sensenig
  • Katie Glavin
  • Joshua A Broghammer
  • Margaret M Higgins
  • Shubham Gupta
  • Clara M Castillejo Becerra
  • Nima Baradaran
  • Rosemary A Kozar
  • Raminder Nirula
  • Jeremy B Myers
  • J. Urol..2020 Jul;:101097JU0000000000001240. doi: 10.1097/JU.0000000000001240.Epub 2020-07-10.

ORF4とORF5aの間に挿入されたマーカー遺伝子を発現するブタの生殖・呼吸器症候群ウイルスの生成

Generation of a porcine reproductive and respiratory syndrome virus expressing a marker gene inserted between ORF4 and ORF5a.
  • Yuxu Wang
  • Wei He
  • Qingqing Li
  • Xin Xie
  • Nian Qin
  • Hao Wang
  • Jiabin Huang
  • Siyuan Lin
  • Kang Ouyang
  • Ying Chen
  • Weijian Huang
  • Zuzhang Wei
  • Arch. Virol..2020 Aug;165(8):1803-1813. 10.1007/s00705-020-04679-3. doi: 10.1007/s00705-020-04679-3.Epub 2020-05-30.

血清中インターロイキン-7およびインターロイキン-10の変化は、薬物を使用しない大うつ病性障害と関連している

Altered serum interleukin-7 and interleukin-10 are associated with drug-free major depressive disorder.
  • Sadia Anjum
  • M M A Shalahuddin Qusar
  • Mohammad Shahriar
  • Sardar Mohammad Ashraful Islam
  • Mohiuddin Ahmed Bhuiyan
  • Md Rabiul Islam
  • Ther Adv Psychopharmacol.2020;10:2045125320916655. 10.1177_2045125320916655. doi: 10.1177/2045125320916655.Epub 2020-04-28.

内視鏡医のフィードバックと大腸内視鏡検査の質指標の改善との関連：システマティックレビューとメタアナリシス

Associations between endoscopist feedback and improvements in colonoscopy quality indicators: a systematic review and meta-analysis.
  • Kirles Bishay
  • Natalia Causada-Calo
  • Michael A Scaffidi
  • Catharine M Walsh
  • John T Anderson
  • Alaa Rostom
  • Catherine Dube
  • Rajesh N Keswani
  • Steven J Heitman
  • Robert J Hilsden
  • Risa Shorr
  • Samir C Grover
  • Nauzer Forbes
  • Gastrointest. Endosc..2020 Apr;S0016-5107(20)34177-8. doi: 10.1016/j.gie.2020.03.3865.Epub 2020-04-21.

関連性はあるのかないのか-炎症のメディエーターと抑うつ性、身体活動、体組成、睡眠の関連性を調査している

Is There an Association or Not?-Investigating the Association of Depressiveness, Physical Activity, Body Composition and Sleep With Mediators of Inflammation.
  • Frank M Schmidt
  • Roland Mergl
  • Juliane Minkwitz
  • Lesca M Holdt
  • Daniel Teupser
  • Ulrich Hegerl
  • Hubertus Himmerich
  • Christian Sander
  • Front Psychiatry.2020;11:563. doi: 10.3389/fpsyt.2020.00563.Epub 2020-06-25.

ホロメタボリーの進化の解明への貢献：アオアシシギChrysopa pallens（神経綱：Chrysopidae）の変態期における頭部内部構造の変化

Contribution to understanding the evolution of holometaboly: transformation of internal head structures during the metamorphosis in the green lacewing Chrysopa pallens (Neuroptera: Chrysopidae).
  • Chenjing Zhao
  • Yuchen Ang
  • Mengqing Wang
  • Caixia Gao
  • Kuiyan Zhang
  • Chufei Tang
  • Xingyue Liu
  • Min Li
  • Ding Yang
  • Rudolf Meier
  • BMC Evol. Biol..2020 Jun;20(1):79. 10.1186/s12862-020-01643-2. doi: 10.1186/s12862-020-01643-2.Epub 2020-06-29.

クルクミンは、オートファジー/アポトーシスを調節することにより、PC12細胞におけるヒ素誘発毒性を緩和する

Curcumin alleviates arsenic-induced toxicity in PC12 cells via modulating autophagy/apoptosis.
  • Md Shiblur Rahaman
  • Subrata Banik
  • Mahmuda Akter
  • Md Mostafizur Rahman
  • Md Tajuddin Sikder
  • Toshiyuki Hosokawa
  • Takeshi Saito
  • Masaaki Kurasaki
  • Ecotoxicol. Environ. Saf..2020 Sep;200:110756. S0147-6513(20)30595-9. doi: 10.1016/j.ecoenv.2020.110756.Epub 2020-05-25.

L-アスパラギナーゼのグルタミナーゼ活性は急性リンパ芽球性白血病に対する前臨床活性の持続性に寄与している

Glutaminase Activity of L-Asparaginase Contributes to Durable Preclinical Activity against Acute Lymphoblastic Leukemia.
  • Wai-Kin Chan
  • Thomas D Horvath
  • Lin Tan
  • Todd Link
  • Karine G Harutyunyan
  • Michael A Pontikos
  • Andriy Anishkin
  • Di Du
  • Leona A Martin
  • Eric Yin
  • Susan B Rempe
  • Sergei Sukharev
  • Marina Konopleva
  • John N Weinstein
  • Philip L Lorenzi
  • Mol. Cancer Ther..2019 09;18(9):1587-1592. 1535-7163.MCT-18-1329. doi: 10.1158/1535-7163.MCT-18-1329.Epub 2019-06-17.

モノアミン輸送体に作用する新規チアゾール系モダフィニル類似体の構造活性相関

Structure-Activity Relationships of Novel Thiazole-Based Modafinil Analogues Acting at Monoamine Transporters.
  • Predrag Kalaba
  • Marija Ilić
  • Nilima Y Aher
  • Vladimir Dragačević
  • Marcus Wieder
  • Martin Zehl
  • Judith Wackerlig
  • Stanislav Beyl
  • Simone B Sartori
  • Karl Ebner
  • Alexander Roller
  • Natalie Lukic
  • Tetyana Beryozkina
  • Eduardo Rene Perez Gonzalez
  • Philip Neill
  • Jawad Akbar Khan
  • Vasiliy Bakulev
  • Johann Jakob Leban
  • Steffen Hering
  • Christian Pifl
  • Nicolas Singewald
  • Jana Lubec
  • Ernst Urban
  • Harald H Sitte
  • Thierry Langer
  • Gert Lubec
  • J. Med. Chem..2020 01;63(1):391-417. doi: 10.1021/acs.jmedchem.9b01938.Epub 2019-12-30.

結核菌を封じ込めたマイコバクテリウム結核感染は、結核菌の感染と同時に異種感染防御を誘導する

Contained Mycobacterium tuberculosis infection induces concomitant and heterologous protection.
  • Johannes Nemeth
  • Gregory S Olson
  • Alissa C Rothchild
  • Ana N Jahn
  • Dat Mai
  • Fergal J Duffy
  • Jared L Delahaye
  • Sanjay Srivatsan
  • Courtney R Plumlee
  • Kevin B Urdahl
  • Elizabeth S Gold
  • Alan Aderem
  • Alan H Diercks
  • PLoS Pathog..2020 Jul;16(7):e1008655. PPATHOGENS-D-20-00605. doi: 10.1371/journal.ppat.1008655.Epub 2020-07-16.

湿式ボールミル法とTEMPOを介在させた酸化技術を組み合わせたセルロースカーボンエアロゲルの合成とそのイオン性色素への吸着性能

Synthesis of cellulose carbon aerogel via combined technology of wet ball-milling and TEMPO-mediated oxidation and its supersorption performance to ionic dyes.
  • Peng Huang
  • Peng Zhang
  • Lujuan Min
  • Jingchun Tang
  • Hongwen Sun
  • Bioresour. Technol..2020 Jul;315:123815. S0960-8524(20)31087-7. doi: 10.1016/j.biortech.2020.123815.Epub 2020-07-10.

C5aはリン酸化プロテオームリモデリングを介して好中球のファゴソーム成熟を阻害する

C5a impairs phagosomal maturation in the neutrophil through phosphoproteomic remodelling.
  • Alexander Jt Wood
  • Arlette M Vassallo
  • Marie-Helene Ruchaud-Sparagano
  • Jonathan Scott
  • Carmelo Zinnato
  • Carmen Gonzalez-Tejedo
  • Kamal Kishore
  • Clive S D'Santos
  • A John Simpson
  • David K Menon
  • Charlotte Summers
  • Edwin R Chilvers
  • Klaus Okkenhaug
  • Andrew Conway Morris
  • JCI Insight.2020 Jul;137029. doi: 10.1172/jci.insight.137029.Epub 2020-07-07.

カプサイシンの摂取は、APP/PS1マウスにおける脳アミロイドβの生成を減少させ、アルツハイマー病型の病態と認知障害を減衰させる

Capsaicin consumption reduces brain amyloid-beta generation and attenuates Alzheimer's disease-type pathology and cognitive deficits in APP/PS1 mice.
  • Jun Wang
  • Bin-Lu Sun
  • Yang Xiang
  • Ding-Yuan Tian
  • Chi Zhu
  • Wei-Wei Li
  • Yu-Hui Liu
  • Xian-Le Bu
  • Lin-Lin Shen
  • Wang-Sheng Jin
  • Zhen Wang
  • Gui-Hua Zeng
  • Wei Xu
  • Li-Yong Chen
  • Xiao-Wei Chen
  • Zhian Hu
  • Zhi-Ming Zhu
  • Weihong Song
  • Hua-Dong Zhou
  • Jin-Tai Yu
  • Yan-Jiang Wang
  • Transl Psychiatry.2020 Jul;10(1):230. 10.1038/s41398-020-00918-y. doi: 10.1038/s41398-020-00918-y.Epub 2020-07-13.

マイクロ波を用いた溶媒抽出とダブルショット分析熱分解法を用いて、浜砂試料中の可塑剤とマイクロプラスチックの定性定量を行った

Microwave-assisted solvent extraction and double-shot analytical pyrolysis for the quali-quantitation of plasticizers and microplastics in beach sand samples.
  • Jacopo La Nasa
  • Greta Biale
  • Marco Mattonai
  • Francesca Modugno
  • J. Hazard. Mater..2020 Jun;401:123287. S0304-3894(20)31276-0. doi: 10.1016/j.jhazmat.2020.123287.Epub 2020-06-23.

固定化されたインパラ（Aepyceros melampus）の低酸素血症を検出するための、異なる装着部位でのパルスオキシメトリの信頼性の評価

Evaluation of the reliability of pulse oximetry, at different attachment sites, to detect hypoxaemia in immobilized impala (Aepyceros melampus).
  • Thembeka K Mtetwa
  • Gareth E Zeiler
  • Liesel Laubscher
  • Silke Pfitzer
  • Leith C R Meyer
  • Vet Anaesth Analg.2020 May;47(3):323-333. S1467-2987(20)30007-6. doi: 10.1016/j.vaa.2019.08.051.Epub 2020-02-04.

縦断的デザインを用いた喘息モニタリングにおける横断的バイオマーカー比較。eNoseの前提

Cross-sectional biomarker comparisons in asthma monitoring using a longitudinal design: The eNose premise.
  • Mahmoud I Abdel-Aziz
  • Rianne de Vries
  • Ariana Lammers
  • Binbin Xu
  • Anne H Neerincx
  • Susanne J H Vijverberg
  • Yennece W F Dagelet
  • Aletta D Kraneveld
  • Urs Frey
  • René Lutter
  • Peter J Sterk
  • Anke H Maitland-van der Zee
  • Anirban Sinha
  • Allergy.2020 Jun;doi: 10.1111/all.14354.Epub 2020-06-16.

HBcと核酸の相互作用の微細な調節因子としてのB型肝炎ウイルス（HBV）コアタンパク質のアルギニンリッチC末端ドメインのリン酸化

Phosphorylation of the Arginine-Rich C-Terminal Domains of the Hepatitis B Virus (HBV) Core Protein as a Fine Regulator of the Interaction between HBc and Nucleic Acid.
  • Hugues de Rocquigny
  • Virgile Rat
  • Florentin Pastor
  • Jean Luc Darlix
  • Christophe Hourioux
  • Philippe Roingeard
  • Viruses.2020 Jul;12(7). E738. doi: 10.3390/v12070738.Epub 2020-07-08.

中国産野生稲（Zizania latifolia）の発芽における抗酸化活性、代謝物、フェノール酸、フラボノイド、フェノール生合成遺伝子の動態（英文

Dynamics of antioxidant activities, metabolites, phenolic acids, flavonoids, and phenolic biosynthetic genes in germinating Chinese wild rice (Zizania latifolia).
  • Cheng Chu
  • Yongmei Du
  • Xiuting Yu
  • John Shi
  • Xiaolong Yuan
  • Xinmin Liu
  • Yanhua Liu
  • Hongbo Zhang
  • Zhongfeng Zhang
  • Ning Yan
  • Food Chem.2020 Jul;318:126483. S0308-8146(20)30345-9. doi: 10.1016/j.foodchem.2020.126483.Epub 2020-02-25.

SNAILはEZRINとAKTの発現を増加させ、MicroRNAネットワークを制御することで、横紋筋肉腫の転移挙動を促進する

SNAIL Promotes Metastatic Behavior of Rhabdomyosarcoma by Increasing EZRIN and AKT Expression and Regulating MicroRNA Networks.
  • Klaudia Skrzypek
  • Marta Kot
  • Paweł Konieczny
  • Artur Nieszporek
  • Anna Kusienicka
  • Małgorzata Lasota
  • Wojciech Bobela
  • Urszula Jankowska
  • Sylwia Kędracka-Krok
  • Marcin Majka
  • Cancers (Basel).2020 Jul;12(7). E1870. doi: 10.3390/cancers12071870.Epub 2020-07-11.

ステロイド抵抗性ネフローゼ症候群または巣状分節状糸球体硬化症を有する韓国小児患者の遺伝学的研究

Genetic Study in Korean Pediatric Patients with Steroid-Resistant Nephrotic Syndrome or Focal Segmental Glomerulosclerosis.
  • Eujin Park
  • Chung Lee
  • Nayoung K D Kim
  • Yo Han Ahn
  • Young Seo Park
  • Joo Hoon Lee
  • Seong Heon Kim
  • Min Hyun Cho
  • Heeyeon Cho
  • Kee Hwan Yoo
  • Jae Il Shin
  • Hee Gyung Kang
  • Il-Soo Ha
  • Woong-Yang Park
  • Hae Il Cheong
  • J Clin Med.2020 Jun;9(6). E2013. doi: 10.3390/jcm9062013.Epub 2020-06-26.

顆粒球コロニー刺激因子（GCSF）は、背側根ガングリアにおける初期のmicroRNA-122発現をアップレギュレートすることで、単球Chemoattractant Protein-1（MCP-1）発現を抑制し、神経障害性疼痛を減衰させることができる

Granulocyte Colony Stimulating Factor (GCSF) Can Attenuate Neuropathic Pain by Suppressing Monocyte Chemoattractant Protein-1 (MCP-1) Expression, through Upregulating the Early MicroRNA-122 Expression in the Dorsal Root Ganglia.
  • Ming-Feng Liao
  • Jung-Lung Hsu
  • Kwok-Tung Lu
  • Po-Kuan Chao
  • Mei-Yun Cheng
  • Hui-Ching Hsu
  • Ai-Lun Lo
  • Yun-Lin Lee
  • Yu-Hui Hung
  • Rong-Kuo Lyu
  • Hung-Chou Kuo
  • Chun-Che Chu
  • Long-Sun Ro
  • Cells.2020 Jul;9(7). E1669. doi: 10.3390/cells9071669.Epub 2020-07-11.

老化する脳。健康な若年者と高齢者のボランティアにおける安静時と触覚刺激や筋肉刺激にさらされている間に取得された機能的なMRIデータのセット

The aging brain: A set of functional MRI data acquired at rest and during exposure to tactile or muscle proprioceptive stimulation in healthy young and older volunteers.
  • Caroline Landelle
  • Julien Sein
  • Jean-Luc Anton
  • Bruno Nazarian
  • Olivier Felician
  • Anne Kavounoudias
  • Data Brief.2020 Aug;31:105939. S2352-3409(20)30833-7. doi: 10.1016/j.dib.2020.105939.Epub 2020-06-27.

精神活性を有するカチノン誘導体ピロバレロンはゼブラフィッシュ（Danio rerio）の運動機能を変化させ、ドーパミン受容体の発現を低下させる

The psychoactive cathinone derivative pyrovalerone alters locomotor activity and decreases dopamine receptor expression in zebrafish (Danio rerio).
  • Christopher Laurence Souders
  • Robert H Davis
  • Hua Qing
  • Xuefang Liang
  • Marcelo Febo
  • Christopher J Martyniuk
  • Brain Behav.2019 11;9(11):e01420. doi: 10.1002/brb3.1420.Epub 2019-10-18.

糖脂質ペプチドワクチン接種は、肝臓レジデントメモリーCD8 T細胞を誘導し、げっ歯類のマラリアから保護する

Glycolipid-peptide vaccination induces liver-resident memory CD8 T cells that protect against rodent malaria.
  • Lauren E Holz
  • Yu Cheng Chua
  • Maria N de Menezes
  • Regan J Anderson
  • Sarah L Draper
  • Benjamin J Compton
  • Susanna T S Chan
  • Juby Mathew
  • Jasmine Li
  • Lukasz Kedzierski
  • Zhongfang Wang
  • Lynette Beattie
  • Matthias H Enders
  • Sonia Ghilas
  • Rose May
  • Thiago M Steiner
  • Joshua Lange
  • Daniel Fernandez-Ruiz
  • Ana Maria Valencia-Hernandez
  • Taryn L Osmond
  • Kathryn J Farrand
  • Rebecca Seneviratna
  • Catarina F Almeida
  • Kirsteen M Tullett
  • Patrick Bertolino
  • David G Bowen
  • Anton Cozijnsen
  • Vanessa Mollard
  • Geoffrey I McFadden
  • Irina Caminschi
  • Mireille H Lahoud
  • Katherine Kedzierska
  • Stephen J Turner
  • Dale I Godfrey
  • Ian F Hermans
  • Gavin F Painter
  • William R Heath
  • Sci Immunol.2020 Jun;5(48). eaaz8035. doi: 10.1126/sciimmunol.aaz8035.

Ｂｍ８６タンパク質に結合したＰ０ペプチドに基づく抗ダニ抗原の機能および質量分析評価

Functional and Mass Spectrometric Evaluation of an Anti-Tick Antigen Based on the P0 Peptide Conjugated to Bm86 Protein.
  • Alina Rodríguez Mallón
  • Luis Javier González
  • Pedro Enrique Encinosa Guzmán
  • Gervasio Henrique Bechara
  • Gustavo Seron Sanches
  • Satomy Pousa
  • Gleysin Cabrera
  • Ania Cabrales
  • Hilda Garay
  • Raúl Mejías
  • José Raúl López Álvarez
  • Yamil Bello Soto
  • Fabiola Almeida
  • Osmany Guirola
  • Rafmary Rodríguez Fernández
  • Alier Fuentes Castillo
  • Luis Méndez
  • Samanta Jiménez
  • Alexei Licea-Navarro
  • Madelón Portela
  • Rosario Durán
  • Mario Pablo Estrada
  • Pathogens.2020 Jun;9(6). E513. doi: 10.3390/pathogens9060513.Epub 2020-06-25.

SOX4は、肝細胞がん細胞のCXCL12を活性化し、生体内での内皮細胞の遊走と血管新生を調節しています

SOX4 activates CXCL12 in hepatocellular carcinoma cells to modulate endothelial cell migration and angiogenesis in vivo.
  • Chi-Neu Tsai
  • Shu-Chuan Yu
  • Chao-Wei Lee
  • Jong-Hwei Su Pang
  • Chun-Hsin Wu
  • Sey-En Lin
  • Yi-Hsiu Chung
  • Chia-Lung Tsai
  • Sen-Yung Hsieh
  • Ming-Chin Yu
  • Oncogene.2020 Jun;39(24):4695-4710. 10.1038/s41388-020-1319-z. doi: 10.1038/s41388-020-1319-z.Epub 2020-05-13.

酵素消化物（E'jiao）は、過酸化水素による細胞死を防ぎ、神経細胞様PC12細胞におけるアミロイドβクリアランスを促進します

Enzyme-digested (E'jiao) prevents hydrogen peroxide-induced cell death and accelerates amyloid beta clearance in neuronal-like PC12 cells.
  • Li Xiao
  • Feng Liao
  • Ryoji Ide
  • Tetsuro Horie
  • Yumei Fan
  • Chikako Saiki
  • Nobuhiko Miwa
  • Neural Regen Res.2020 Dec;15(12):2270-2272. NeuralRegenRes_2020_15_12_2270_285000. doi: 10.4103/1673-5374.285000.

オーストラリア先住民の動脈構造と機能に対する歯周治療の効果：無作為化比較試験

Effect of periodontal therapy on arterial structure and function among aboriginal australians: a randomized, controlled trial.
  • Kostas Kapellas
  • Louise J Maple-Brown
  • Lisa M Jamieson
  • Loc G Do
  • Kerin O'Dea
  • Alex Brown
  • Tommy Y Cai
  • Nicholas M Anstey
  • David R Sullivan
  • Hao Wang
  • David S Celermajer
  • Gary D Slade
  • Michael R Skilton
  • Hypertension.2014 Oct;64(4):702-8. HYPERTENSIONAHA.114.03359. doi: 10.1161/HYPERTENSIONAHA.114.03359.Epub 2014-06-23.

UBE2Tのホモ接合型ミスセンス変異は軽度のファンコニー貧血の表現型と関連している

Homozygous missense variant in UBE2T is associated with mild Fanconi anemia phenotype.
  • Laura Schultz-Rogers
  • Francis P Lach
  • Kimberly A Rickman
  • Alejandro Ferrer
  • Abhishek A Mangaonkar
  • Tanya L Schwab
  • Christopher T Schmitz
  • Karl J Clark
  • Nikita R Dsouza
  • Michael T Zimmermann
  • Mark Litzow
  • Nicole Jacobi
  • Eric W Klee
  • Agata Smogorzewska
  • Mrinal M Patnaik
  • Haematologica.2020 Jul;haematol.2020.259275. doi: 10.3324/haematol.2020.259275.Epub 2020-07-09.

FRETベースのタウ播種アッセイは、タウフィラメントのプリオン様テンプル化された集合体を表していない

FRET-based Tau seeding assay does not represent prion-like templated assembly of Tau filaments.
  • Senthilvelrajan Kaniyappan
  • Katharina Tepper
  • Jacek Biernat
  • Ram Reddy Chandupatla
  • Sabrina Hübschmann
  • Stephan Irsen
  • Sandra Bicher
  • Christoph Klatt
  • Eva-Maria Mandelkow
  • Eckhard Mandelkow
  • Mol Neurodegener.2020 Jul;15(1):39. 10.1186/s13024-020-00389-1. doi: 10.1186/s13024-020-00389-1.Epub 2020-07-16.

GNASの遺伝子変異との関連性が確認された偽性副甲状腺機能低下症Ia型患者におけるイロプロスト誘発性血小板抑制およびリン酸化プロテオーム変化の障害

Impaired iloprost-induced platelet inhibition and phosphoproteome changes in patients with confirmed pseudohypoparathyroidism type Ia, linked to genetic mutations in GNAS.
  • Frauke Swieringa
  • Fiorella A Solari
  • Oliver Pagel
  • Florian Beck
  • Jingnan Huang
  • Marion A H Feijge
  • Kerstin Jurk
  • Irene M L W Körver-Keularts
  • Nadine J A Mattheij
  • Jörg Faber
  • Joachim Pohlenz
  • Alexandra Russo
  • Connie T R M Stumpel
  • Dirk E Schrander
  • Barbara Zieger
  • Paola E J van der Meijden
  • René P Zahedi
  • Albert Sickmann
  • Johan W M Heemskerk
  • Sci Rep.2020 Jul;10(1):11389. 10.1038/s41598-020-68379-3. doi: 10.1038/s41598-020-68379-3.Epub 2020-07-09.

薬物を注射する人および HIV/AIDS と共に生きる女性性労働者における HCV および／または HBV の共同感染の世界的有病率：システマティックレビューおよびメタアナリシス

Global prevalence of HCV and/or HBV coinfections among people who inject drugs and female sex workers who live with HIV/AIDS: a systematic review and meta-analysis.
  • Roya Rashti
  • Seyed Moayed Alavian
  • Yousef Moradi
  • Heidar Sharafi
  • Amjad Mohamadi Bolbanabad
  • Daem Roshani
  • Ghobad Moradi
  • Arch. Virol..2020 Jul;10.1007/s00705-020-04716-1. doi: 10.1007/s00705-020-04716-1.Epub 2020-07-02.

非セリアック小麦感受性患者の直腸ムコサにおけるTNF-α、IL-17およびIL-22の産生。適応免疫の役割

TNF-α, IL-17 AND IL-22 PRODUCTION IN THE RECTAL MUCOSA OF NON-CELIAC WHEAT SENSITIVITY PATIENTS: ROLE OF ADAPTIVE IMMUNITY.
  • Pasquale Mansueto
  • Diana Di Liberto
  • Francesca Fayer
  • Maurizio Soresi
  • Girolamo Geraci
  • Antonino Giulio Giannone
  • Aurelio Seidita
  • Alberto D'Alcamo
  • Francesco La Blasca
  • Marianna Lo Pizzo
  • Ada Maria Florena
  • Francesco Dieli
  • Antonio Carroccio
  • Am. J. Physiol. Gastrointest. Liver Physiol..2020 Jul;doi: 10.1152/ajpgi.00104.2020.Epub 2020-07-13.

ボトムアップアプローチによるコアシェル型ナノスケールゼロバレント鉄(CS-nZVI)の合成。Cu(II)イオン吸着を利用した物理化学的・分光学的特性評価を行った

Bottom-up approach synthesis of core-shell nanoscale zerovalent iron (CS-nZVI): Physicochemical and spectroscopic characterization with Cu(II) ions adsorption application.
  • Adewumi Oluwasogo Dada
  • Folahan Amoo Adekola
  • Ezekiel Oluyemi Odebunmi
  • Fehintoluwa Elizabeth Dada
  • Olugbenga Solomon Bello
  • Adeniyi Sunday Ogunlaja
  • MethodsX.2020;7:100976. S2215-0161(20)30196-5. doi: 10.1016/j.mex.2020.100976.Epub 2020-06-25.

ニパーウイルス融合糖タンパク質の第三らせんドメインが膜融合カスケードの初期段階と後期段階の両方を修飾することを発見した

Third Helical Domain of the Nipah Virus Fusion Glycoprotein Modulates Both Early and Late Steps in the Membrane Fusion Cascade.
  • J Lizbeth Reyes Zamora
  • Victoria Ortega
  • Gunner P Johnston
  • Jenny Li
  • Nicole M André
  • I Abrrey Monreal
  • Erik M Contreras
  • Gary R Whittaker
  • Hector C Aguilar
  • J. Virol..2020 Jul;JVI.00644-20. doi: 10.1128/JVI.00644-20.Epub 2020-07-15.

抗生物質耐性遺伝子の時間的動態と、14種類の抗生物質による選択下にある水底堆積物中成層における細菌群集との関連

Temporal dynamics of antibiotic resistant genes and their association with the bacterial community in a water-sediment mesocosm under selection by 14 antibiotics.
  • Chengxun Deng
  • Xiaowei Liu
  • Lanlan Li
  • Jianghong Shi
  • Wei Guo
  • Jianhui Xue
  • Environ Int.2020 Apr;137:105554. S0160-4120(19)34366-1. doi: 10.1016/j.envint.2020.105554.Epub 2020-02-18.

は、自律的なBCRシグナル伝達を可能にする一点変異の獲得によるCLLの遺伝的危険因子である

is an inherited risk factor for CLL through the acquisition of a single-point mutation enabling autonomous BCR signaling.
  • Palash C Maity
  • Mayas Bilal
  • Marvyn T Koning
  • Marc Young
  • Cornelis A M van Bergen
  • Valerio Renna
  • Antonella Nicolò
  • Moumita Datta
  • Eva Gentner-Göbel
  • Rob S Barendse
  • Sebastiaan F Somers
  • Ruben A L de Groen
  • Joost S P Vermaat
  • Daniela Steinbrecher
  • Christof Schneider
  • Eugen Tausch
  • Tamara Bittolo
  • Riccardo Bomben
  • Andrea Nicola Mazzarello
  • Giovanni Del Poeta
  • Wilma G M Kroes
  • J Tom van Wezel
  • Katharina Imkeller
  • Christian E Busse
  • Massimo Degano
  • Tamam Bakchoul
  • Axel Ronald Schulz
  • Henrik Mei
  • Paolo Ghia
  • Konstantia Kotta
  • Kostas Stamatopoulos
  • Hedda Wardemann
  • Antonella Zucchetto
  • Nicholas Chiorazzi
  • Valter Gattei
  • Stephan Stilgenbauer
  • Hendrik Veelken
  • Hassan Jumaa
  • Proc. Natl. Acad. Sci. U.S.A..2020 02;117(8):4320-4327. 1913810117. doi: 10.1073/pnas.1913810117.Epub 2020-02-11.

メタゲノム解析とネットワーク解析により、埋立排水流通システムにおける抗生物質レジストームと細菌種のプロファイルと共起パターンを解読した

Metagenomic and network analyses decipher profiles and co-occurrence patterns of antibiotic resistome and bacterial taxa in the reclaimed wastewater distribution system.
  • Guijuan Zhang
  • Yuntao Guan
  • Renxin Zhao
  • Jie Feng
  • Jin Huang
  • Liping Ma
  • Bing Li
  • J. Hazard. Mater..2020 Jun;400:123170. S0304-3894(20)31159-6. doi: 10.1016/j.jhazmat.2020.123170.Epub 2020-06-11.

コカインとアルコールの併用摂取によって引き起こされた重度の横紋筋融解症と急性腎不全を呈し、血液透析依存性の末期腎疾患に至る。症例報告と文献レビュー

Cocaine and Alcohol Co-Ingestion-Induced Severe Rhabdomyolysis With Acute Kidney Injury Culminating in Hemodialysis-Dependent End-Stage Renal Disease: A Case Report and Literature Review.
  • Sasmit Roy
  • Venu Madhav Konala
  • Sreedhar Adapa
  • Srikanth Naramala
  • Subhasish Bose
  • Cureus.2020 Jun;12(6):e8595. doi: 10.7759/cureus.8595.Epub 2020-06-13.

極薄グラファイトナノシートに埋め込まれたMoドープSnO2ナノ粒子は、リチウムイオン電池用負極材料として、高可逆容量、優れた速度、長寿命を実現している

Mo-doped SnO2 nanoparticles embedded in ultrathin graphite nanosheets as a high reversible capacity, superior rate and long cycle life anode material for lithium-ion batteries.
  • Yefeng Feng
  • Kaidan Wu
  • Yukun Sun
  • Zhiling Guo
  • Jin Ke
  • Xiping Huang
  • Chen Bai
  • Huafeng Dong
  • Deping Xiong
  • Miao He
  • Langmuir.2020 Jul;doi: 10.1021/acs.langmuir.0c01604.Epub 2020-07-17.

乳癌における乳頭・乳輪動脈複合体への動脈供給に対する低濃度・低流量の造影剤を用いた二重エネルギーコンピュータ断層撮影による単色画像の画質を従来のコンピュータ断層撮影による血管造影と比較して評価した

Evaluating the Image Quality of Monoenergetic Images From Dual-Energy Computed Tomography With Low-Concentration and Low-Flow-Rate Contrast Media for the Arterials Supply to the Nipple-Areola Complex in Breast Cancer Compared With Conventional Computed Tomography Angiography.
  • Xiangfei Zeng
  • Xiaoxia Wang
  • Huifang Chen
  • Daihong Liu
  • Jinfang Shi
  • Jing Zhang
  • Xiaoqin Li
  • Liyin Zhang
  • Yi Yang
  • Jiuquan Zhang
  • J Comput Assist Tomogr.2020 Jul;doi: 10.1097/RCT.0000000000001063.Epub 2020-07-06.

中国人集団における血清尿酸と眼底動脈硬化症の発症との性差別関連。レトロスペクティブな横断的研究

Gender-Specific Association between Serum Uric Acid and Incident Fundus Arteriosclerosis in Chinese Population: A Retrospective Cross-Sectional Study.
  • Qianqian Liu
  • Chunxing Liu
  • Yonghui Gao
  • Xinyan Zhang
  • Nengjun Yi
  • Jianping Cao
  • Yamin Wang
  • Yongbin Jiang
  • Zaixiang Tang
  • Sci Rep.2020 May;10(1):8595. 10.1038/s41598-020-65575-z. doi: 10.1038/s41598-020-65575-z.Epub 2020-05-25.

COVID-19時代の耳鼻咽喉科手術における乳頭切除術中のエアロゾル分散とカスタム緩和戦略

Aerosol Dispersion During Mastoidectomy and Custom Mitigation Strategies for Otologic Surgery in the COVID-19 Era.
  • Divya A Chari
  • Alan D Workman
  • Jenny X Chen
  • David H Jung
  • Dunia Abdul-Aziz
  • Elliott D Kozin
  • Aaron K Remenschneider
  • Daniel J Lee
  • D Bradley Welling
  • Benjamin S Bleier
  • Alicia M Quesnel
  • Otolaryngol Head Neck Surg.2020 Jul;:194599820941835. doi: 10.1177/0194599820941835.Epub 2020-07-14.

エフェクターを含まない状態と結合した状態のプレQ1-Iリボスイッチの解析から、代謝産物をプログラムした核酸塩基積層スパインが遺伝子制御を制御していることが明らかになった

Analysis of a preQ1-I riboswitch in effector-free and bound states reveals a metabolite-programmed nucleobase-stacking spine that controls gene regulation.
  • Griffin M Schroeder
  • Debapratim Dutta
  • Chapin E Cavender
  • Jermaine L Jenkins
  • Elizabeth M Pritchett
  • Cameron D Baker
  • John M Ashton
  • David H Mathews
  • Joseph E Wedekind
  • Nucleic Acids Res..2020 Jun;gkaa546. doi: 10.1093/nar/gkaa546.Epub 2020-06-29.

Baicalinは、Notch1-Snail軸を介したポッドサイトのEMTを阻害することで、アドリアマイシン誘発性の巣状分節性糸球体硬化症と蛋白尿を緩和する

Baicalin alleviates adriamycin-induced focal segmental glomerulosclerosis and proteinuria by inhibiting the Notch1-Snail axis mediated podocyte EMT.
  • Yitian Dou
  • Yichun Shang
  • Yongmei Shen
  • Jingtian Qu
  • Chunliu Liu
  • Jiasong Cao
  • Life Sci..2020 Jun;:118010. S0024-3205(20)30760-8. doi: 10.1016/j.lfs.2020.118010.Epub 2020-06-26.

ウイルスポリメラーゼとゲノムの3'非翻訳領域との間の正のエピスタシスは、デングウイルスの疫学的な適合性を明らかにした

Positive epistasis between viral polymerase and the 3' untranslated region of its genome reveals the epidemiologic fitness of dengue virus.
  • Ayesa Syenina
  • Dhanasekaran Vijaykrishna
  • Esther Shuyi Gan
  • Hwee Cheng Tan
  • Milly M Choy
  • Tanamas Siriphanitchakorn
  • Colin Cheng
  • Subhash G Vasudevan
  • Eng Eong Ooi
  • Proc. Natl. Acad. Sci. U.S.A..2020 May;117(20):11038-11047. 1919287117. doi: 10.1073/pnas.1919287117.Epub 2020-05-04.

サイバーナイフM6システムを用いた定位放射線治療後の肺癌患者における放射線誘発性二次癌リスクの評価

Radiation-Induced Secondary Cancer Risk Assessment in Patients With Lung Cancer After Stereotactic Body Radiotherapy Using the CyberKnife M6 System With Lung-Optimized Treatment.
  • Pei-Ju Chao
  • I-Hsing Tsai
  • Chun-Chieh Huang
  • Chih-Hsueh Lin
  • Chin-Shiuh Shieh
  • Yang-Wei Hsieh
  • Pei-Ying Yang
  • Hsiao-Fei Lee
  • Tsair-Fwu Lee
  • Front Bioeng Biotechnol.2020;8:306. doi: 10.3389/fbioe.2020.00306.Epub 2020-05-07.

PI3Kδ/CK1εのデュアルPI3Kδ/CK1ε阻害剤であるumbralisibは、CLL T細胞に対してユニークな免疫調節作用を示します

The dual PI3Kδ/CK1ε inhibitor umbralisib exhibits unique immunomodulatory effects on CLL T cells.
  • Kamira Maharaj
  • John J Powers
  • Alex Achille
  • Melanie Mediavilla-Varela
  • Wael Gamal
  • Karen L Burger
  • Renee Fonseca
  • Kun Jiang
  • Hari P Miskin
  • Dave Maryanski
  • Andrii Monastyrskyi
  • Derek R Duckett
  • William R Roush
  • John L Cleveland
  • Eva Sahakian
  • Javier Pinilla-Ibarz
  • Blood Adv.2020 Jul;4(13):3072-3084. 461272. doi: 10.1182/bloodadvances.2020001800.

エチオピア、アディスアベバ、アディスアベバのBlack Lion専門病院成人腫瘍病棟における乳がん患者における再発の発生率と予測因子。生存期間分析を伴うレトロスペクティブ・フォローアップ研究

Incidence and Predictors of Recurrence among Breast Cancer Patients in Black Lion Specialized Hospital Adult Oncology Unit, Addis Ababa, Ethiopia: Retrospective Follow-up Study with Survival Analysis.
  • Wondimeneh Shibabaw Shiferaw
  • Yared Asmare Aynalem
  • Tadesse Yirga Akalu
  • Tefera Mulugeta Demelew
  • J Cancer Prev.2020 Jun;25(2):111-118. JCP-25-111. doi: 10.15430/JCP.2020.25.2.111.

スコポラミンの慢性投与は、ウィスターラットの海馬においてGSK3βP9、βセクレターゼ、アミロイドβ、酸化ストレスを増加させた

Chronic Administration of Scopolamine Increased GSK3βP9, Beta Secretase, Amyloid Beta, and Oxidative Stress in the Hippocampus of Wistar Rats.
  • Maricarmen Hernández-Rodríguez
  • Ivonne Maciel Arciniega-Martínez
  • Iohanan Daniel García-Marín
  • José Correa-Basurto
  • Martha Cecilia Rosales-Hernández
  • Mol. Neurobiol..2020 Jul;10.1007/s12035-020-02009-x. doi: 10.1007/s12035-020-02009-x.Epub 2020-07-07.

アフラトキシン生合成経路のD,M,R,S遺伝子の発現を低下させることにより、果実や果実、カプサイシン、ピペリンのアフラトキシン産生を抑制する効果がある

Inhibitory effect of and fruits, capsaicin and piperine on aflatoxins production in by downregulating the expression of D, M, R, and S genes of aflatoxins biosynthetic pathway.
  • Génesis V Buitimea-Cantúa
  • Nydia E Buitimea-Cantúa
  • María Del Refugio Rocha-Pizaña
  • Alejandro Hernández-Morales
  • Elisa Magaña-Barajas
  • Jorge Molina-Torres
  • J Environ Sci Health B.2020 Jul;:1-9. doi: 10.1080/03601234.2020.1787758.Epub 2020-07-11.

イングランドの黒人、アジア人、少数民族グループは、COVID-19：NHS死亡データの間接的な標準化により死亡リスクが高まる

Black, Asian and Minority Ethnic groups in England are at increased risk of death from COVID-19: indirect standardisation of NHS mortality data.
  • Robert W Aldridge
  • Dan Lewer
  • Srinivasa Vittal Katikireddi
  • Rohini Mathur
  • Neha Pathak
  • Rachel Burns
  • Ellen B Fragaszy
  • Anne M Johnson
  • Delan Devakumar
  • Ibrahim Abubakar
  • Andrew Hayward
  • Wellcome Open Res.2020;5:88. doi: 10.12688/wellcomeopenres.15922.2.Epub 2020-06-24.

ATPGD1（カルノシン合成酵素）の心臓特異的な過剰発現は、ヒスチジンジペプチドレベルを増加させ、心筋虚血再灌流傷害を防ぐことができます

Cardiospecific Overexpression of ATPGD1 (Carnosine Synthase) Increases Histidine Dipeptide Levels and Prevents Myocardial Ischemia Reperfusion Injury.
  • Jingjing Zhao
  • Daniel J Conklin
  • Yiru Guo
  • Xiang Zhang
  • Detlef Obal
  • Luping Guo
  • Ganapathy Jagatheesan
  • Kartik Katragadda
  • Liqing He
  • Xinmin Yin
  • Md Aminul Islam Prodhan
  • Jasmit Shah
  • David Hoetker
  • Amit Kumar
  • Vijay Kumar
  • Michael F Wempe
  • Aruni Bhatnagar
  • Shahid P Baba
  • J Am Heart Assoc.2020 Jun;9(12):e015222. doi: 10.1161/JAHA.119.015222.Epub 2020-06-09.

フタル酸塩および環境フェノール類への暴露と腎機能マーカーとの関連。韓国国民環境保健調査（KoNEHS）2015-2017．

Association of exposure to phthalates and environmental phenolics with markers of kidney function: Korean National Environmental Health Survey (KoNEHS) 2015-2017.
  • Inae Lee
  • Jae Yoon Park
  • Sunmi Kim
  • Jung Nam An
  • Jeonghwan Lee
  • Hyunwoong Park
  • Sun Kyoung Jung
  • Sung Yeon Kim
  • Jung Pyo Lee
  • Kyungho Choi
  • Environ Int.2020 Jul;143:105877. S0160-4120(20)31832-8. doi: 10.1016/j.envint.2020.105877.Epub 2020-07-06.

成人セリアック病では診断時のアラーム症状の頻度が高いにもかかわらず、上部内視鏡的消化管所見の有病率は低い

Low prevalence of upper endoscopic gastrointestinal findings despite high frequency of alarm symptoms at the time of diagnosis in adult coeliac disease.
  • Stiliano Maimaris
  • Annalisa Schiepatti
  • Gian Marco Gabrielli
  • Martina Costetti
  • Stefania Costa
  • David S Sanders
  • Fabiana Zingone
  • Antonio Carroccio
  • Carolina Ciacci
  • Antonio Di Sabatino
  • Federico Biagi
  • Eur J Gastroenterol Hepatol.2020 Jul;doi: 10.1097/MEG.0000000000001829.Epub 2020-07-14.

スペインの13都市における廃水分析によるフタル酸系可塑剤への人口曝露の評価

Assessing population exposure to phthalate plasticizers in thirteen Spanish cities through the analysis of wastewater.
  • Iria González-Mariño
  • Leticia Ares
  • Rosa Montes
  • Rosario Rodil
  • Rafael Cela
  • Ester López-García
  • Cristina Postigo
  • Miren López de Alda
  • Eva Pocurull
  • Rosa María Marcé
  • Lubertus Bijlsma
  • Félix Hernández
  • Yolanda Picó
  • Vicente Andreu
  • Andreu Rico
  • Yolanda Valcárcel
  • Manuel Miró
  • Néstor Etxebarria
  • José Benito Quintana
  • J. Hazard. Mater..2020 Jun;401:123272. S0304-3894(20)31261-9. doi: 10.1016/j.jhazmat.2020.123272.Epub 2020-06-22.

"適切な時期は生後すぐ"：エスワティニにおけるポイント・オブ・ケア出産検査の受容性：乳児保育者、医療従事者、政策立案者からの質的な結果

"The right time is just after birth": acceptability of point-of-care birth testing in Eswatini: qualitative results from infant caregivers, health care workers, and policymakers.
  • Emma Sacks
  • Philisiwe Khumalo
  • Bhekisisa Tsabedze
  • William Montgomery
  • Nobuhle Mthethwa
  • Bonisile Nhlabatsi
  • Thembie Masuku
  • Jennifer Cohn
  • Caspian Chouraya
  • BMC Pediatr.2020 Jul;20(1):347. 10.1186/s12887-020-02242-2. doi: 10.1186/s12887-020-02242-2.Epub 2020-07-15.

プララトレキサート耐性T細胞リンパ腫株の作製により、エピジェネティック修飾剤を用いて克服される後天的薬剤耐性の2つのパターンが明らかになった

Generation of pralatrexate resistant T-cell lymphoma lines reveals two patterns of acquired drug resistance that is overcome with epigenetic modifiers.
  • Luigi Scotto
  • Cristina Kinahan
  • Beatrice Casadei
  • Michael Mangone
  • Eugene Douglass
  • Murty V Vundavalli
  • Enrica Marchi
  • Helen Ma
  • Changchun George
  • Francesca Montanari
  • Andrea Califano
  • Owen A O'Connor
  • Genes Chromosomes Cancer.2020 Jul;doi: 10.1002/gcc.22884.Epub 2020-07-02.

バージニア州とニュージャージー州のアジア・ロングホーンテッド・ダニ（Haemaphysalis longicornis）陽性サイトでの野生動物宿主および環境中のダニの調査、2018年

Surveys for ticks on wildlife hosts and in the environment at Asian longhorned tick (Haemaphysalis longicornis)-positive sites in Virginia and New Jersey, 2018.
  • Seth A White
  • Sarah N Bevins
  • Mark G Ruder
  • David Shaw
  • Stacey L Vigil
  • Adam Randall
  • Thomas J Deliberto
  • Kristen Dominguez
  • Alec T Thompson
  • James W Mertins
  • Jeffery T Alfred
  • Michael J Yabsley
  • Transbound Emerg Dis.2020 Jul;doi: 10.1111/tbed.13722.Epub 2020-07-08.

藻類-クラッドセランの放牧者-オオイトトンボ類の食物連鎖に及ぼすノルフロキサシンの影響。藻類の形態学が媒介する栄養連鎖のカスケード

Effect of norfloxacin on algae-cladoceran grazer-larval damselfly food chains: Algal morphology-mediated trophic cascades.
  • Lingling Wan
  • Yaoyue Long
  • Jin Hui
  • Hao Zhang
  • Zhiyong Hou
  • Jiexin Tan
  • Ying Pan
  • Shucun Sun
  • Chemosphere.2020 Oct;256:127166. S0045-6535(20)31359-X. doi: 10.1016/j.chemosphere.2020.127166.Epub 2020-05-24.

衝撃下顎第三大臼歯手術における術後疼痛、腫脹、三叉神経症に対する外科的ドレーン配置とキネシオロジーテープの使用の比較

Comparison of Surgical Drain Placement With Use of Kinesiologic Tape on Postoperative Pain, Swelling, and Trismus in Impacted Mandibular Third Molar Surgery.
  • Dilek Menziletoglu
  • Arif Yigit Guler
  • Funda Basturk
  • Bozkurt Kubilay Isik
  • J. Oral Maxillofac. Surg..2020 Jun;S0278-2391(20)30666-2. doi: 10.1016/j.joms.2020.06.023.Epub 2020-06-22.

Grygar（2020）の「軍事汚染されたサイトの潜在的なフィトマネジメントとバイオ燃料作物miscanthus x giganteusを使用したバイオマス生産」のコメントへの対応-Pidlisnyuk etal.(2019).環境汚染、261：113038

Response to Grygar (2020) comments on "Potential phytomanagement of military polluted sites and biomass production using biofuel crop miscanthus x giganteus"- Pidlisnyuk et al. (2019). Environmental pollution, 261: 113038.
  • Valentina Pidlisnyuk
  • Larry Erickson
  • Tatyana Stefanovska
  • Ganga Hettiarachchi
  • Lawrence Davis
  • Josef Trögl
  • Pavlo Shapoval
  • Environ. Pollut..2020 Jun;:115037. S0269-7491(20)34826-0. doi: 10.1016/j.envpol.2020.115037.Epub 2020-06-20.

オールトランスレチノイン酸は血小板機能と血栓形成に障害を与え、プロテインキナーゼCßI/δリン酸化を阻害する

All-Trans Retinoic Acid Impairs Platelet Function and Thrombus Formation and Inhibits Protein Kinase CßI/δ Phosphorylation.
  • Qi Luo
  • Guangyu Wei
  • Xiamin Wang
  • Xiaoqi Xu
  • Wen Ju
  • Zhenyu Li
  • Elizabeth E Gardiner
  • Robert K Andrews
  • Lingyu Zeng
  • Kailin Xu
  • Jianlin Qiao
  • Thromb. Haemost..2019 10;119(10):1655-1664. doi: 10.1055/s-0039-1693737.Epub 2019-08-01.

カルノシンは、ポッドサイトにおける細胞ストレス応答を活性化し、糖化ストレスおよび脂質過酸化ストレスを減少させる

Carnosine Activates Cellular Stress Response in Podocytes and Reduces Glycative and Lipoperoxidative Stress.
  • Maria Scuto
  • Angela Trovato Salinaro
  • Sergio Modafferi
  • Alessandra Polimeni
  • Tilman Pfeffer
  • Tim Weigand
  • Vittorio Calabrese
  • Claus Peter Schmitt
  • Verena Peters
  • Biomedicines.2020 Jun;8(6). E177. doi: 10.3390/biomedicines8060177.Epub 2020-06-26.

小児におけるJJステントの術後のシームレスな抜去。JJステントを尿道バルーンカテーテルの先端に固定することで、さらなる手術を避けることができます

Seamless post-operative removal of JJ stents in the paediatric population: Securing the JJ stent to the tip of the urethral balloon catheter avoids a further operation.
  • Lewis Taylor
  • Alexander Cho
  • Naima Smeulders
  • J Pediatr Urol.2020 Jun;S1477-5131(20)30405-8. doi: 10.1016/j.jpurol.2020.06.028.Epub 2020-06-26.

Brucella FtrAにおける保存されたCu結合残基のコンフォメーション安定性と機能性の発現における役割を調べる

Investigating the roles of the conserved Cu-binding residues on Brucella FtrA in producing conformational stability and functionality.
  • Sambuddha Banerjee
  • Ryan J Garrigues
  • Mina N Chanakira
  • Jacob J Negron-Olivo
  • Yasmene H Odeh
  • Anne M Spuches
  • R Martin Roop
  • Joshua Edison Pitzer
  • Daniel W Martin
  • Saumya Dasgupta
  • J. Inorg. Biochem..2020 Jun;210:111162. S0162-0134(20)30190-2. doi: 10.1016/j.jinorgbio.2020.111162.Epub 2020-06-23.

2,5-二置換および1,2,5-三置換ベンズイミダゾールの合成と抗菌活性

Synthesis and Antimycobacterial Activity of 2,5-Disubstituted and 1,2,5-Trisubstituted Benzimidazoles.
  • Rogelio Jiménez-Juárez
  • Wendy Cruz-Chávez
  • Nayeli de Jesús-Ramírez
  • Guadalupe Ivonne Castro-Ramírez
  • Itzel Uribe-González
  • Gabriela Martínez-Mejía
  • Ricardo Ruiz-Nicolás
  • Charmina Aguirre-Alvarado
  • Nayeli Shantal Castrejón-Jiménez
  • Blanca Estela García-Pérez
  • Front Chem.2020;8:433. doi: 10.3389/fchem.2020.00433.Epub 2020-06-19.

BICD2のC末端切断によるダイニン媒介核転座の障害は、神経細胞の遊走障害とヒトの脳奇形につながる

Impairment in dynein-mediated nuclear translocation by BICD2 C-terminal truncation leads to neuronal migration defect and human brain malformation.
  • Meng-Han Tsai
  • Haw-Yuan Cheng
  • Fang-Shin Nian
  • Chen Liu
  • Nian-Hsin Chao
  • Kuo-Liang Chiang
  • Shu-Fang Chen
  • Jin-Wu Tsai
  • Acta Neuropathol Commun.2020 Jul;8(1):106. 10.1186/s40478-020-00971-0. doi: 10.1186/s40478-020-00971-0.Epub 2020-07-14.

本研究では、比色スクリーニング法を用いて分離された土壌中のDNRA細菌の生理的特徴を明らかにし、DNRA活性の生態生理学的制御にNOが関与していることを示唆した

Physiological characterization of soil DNRA bacteria isolated via a colorimetric screening method implies involvement of NO in ecophysiological regulation of DNRA activity.
  • Hokwan Heo
  • Miye Kwon
  • Bongkeun Song
  • Sukhwan Yoon
  • Appl. Environ. Microbiol..2020 Jul;AEM.01054-20. doi: 10.1128/AEM.01054-20.Epub 2020-07-06.

Plasmodium vivax reticulocyte binding protein 2bに対する抗体は、ブラジルとタイのマラリア感染率の低い地域に住む集団において、P. vivaxマラリアに対する保護と関連しています

Antibodies to Plasmodium vivax reticulocyte binding protein 2b are associated with protection against P. vivax malaria in populations living in low malaria transmission regions of Brazil and Thailand.
  • Wen-Qiang He
  • Stephan Karl
  • Michael T White
  • Wang Nguitragool
  • Wuelton Monteiro
  • Andrea Kuehn
  • Jakub Gruszczyk
  • Camila T França
  • Jetsumon Sattabongkot
  • Marcus V G Lacerda
  • Wai-Hong Tham
  • Ivo Mueller
  • PLoS Negl Trop Dis.2019 08;13(8):e0007596. PNTD-D-18-01393. doi: 10.1371/journal.pntd.0007596.Epub 2019-08-19.

北欧の典型的な住宅を対象とした土壌中の放射性汚染物質の移動、居住者の居住状況及び汚染の変動がアイソ線量線に及ぼす影響

Influence of the migration of radioactive contaminants in soil, resident occupancy, and variability in contamination on isodose lines for typical Northern European houses.
  • Yvonne Hinrichsen
  • Robert Finck
  • Johan Martinsson
  • Christopher Rääf
  • Kasper Grann Andersson
  • Sci Rep.2019 05;9(1):7876. 10.1038/s41598-019-44392-z. doi: 10.1038/s41598-019-44392-z.Epub 2019-05-27.

臨床サンプル中のサイロキシン検出のための多機能DNA/ロジウムナノプレートヘテロレイヤーからなる電気化学バイオセンサーの作製

Fabrication of electrochemical biosensor composed of multi-functional DNA/rhodium nanoplate heterolayer for thyroxine detection in clinical sample.
  • Sun Yong Park
  • Jinmyeong Kim
  • Gyeonghye Yim
  • Hongje Jang
  • Yeonju Lee
  • Soo Min Kim
  • Chulhwan Park
  • Min-Ho Lee
  • Taek Lee
  • Colloids Surf B Biointerfaces.2020 Jul;195:111240. S0927-7765(20)30596-8. doi: 10.1016/j.colsurfb.2020.111240.Epub 2020-07-02.

GATA1 病原性バリアントのスクリーニングを受けた一過性異常骨髄球増殖症を有するダウン症候群新生児のコホートにおける全血球数の違い

Complete blood count differences in a cohort of Down syndrome neonates with transient abnormal myelopoiesis screened for GATA1 pathogenic variants.
  • Mireya Orozco-Vela
  • Alfredo Corona-Rivera
  • Rosa Margarita Cruz-Osorio
  • Lucero Mendoza-Maldonado
  • Aurea Márquez-Mora
  • César Cenobio Barba-Barba
  • Christian Peña-Padilla
  • Alejandra Baldomero-López
  • Lucina Bobadilla-Morales
  • Jorge Román Corona-Rivera
  • Am. J. Med. Genet. A.2020 Jul;doi: 10.1002/ajmg.a.61748.Epub 2020-07-18.

体液性免疫は、生殖細胞を排除することなく、マラリア原虫の再発を防ぎます

Humoral immunity prevents clinical malaria during Plasmodium relapses without eliminating gametocytes.
  • Chester J Joyner
  • Cristiana F A Brito
  • Celia L Saney
  • Regina Joice Cordy
  • Maren L Smith
  • Stacey A Lapp
  • Monica Cabrera-Mora
  • Shuya Kyu
  • Nicolas Lackman
  • Mustafa V Nural
  • Jeremy D DeBarry
  • Jessica C Kissinger
  • Mark P Styczynski
  • F Eun-Hyung Lee
  • Tracey J Lamb
  • Mary R Galinski
  • PLoS Pathog..2019 09;15(9):e1007974. PPATHOGENS-D-18-02403. doi: 10.1371/journal.ppat.1007974.Epub 2019-09-19.

低分子阻害剤 OGP46 は、BCR-ABL/JAK-STAT 経路を介したイマチニブ耐性 BCR-ABL 変異に対して有効である

A Small Molecule Inhibitor, OGP46, Is Effective against Imatinib-Resistant BCR-ABL Mutations via the BCR-ABL/JAK-STAT Pathway.
  • Liuya Wei
  • Yang Yang
  • Pranav Gupta
  • Aihong Wang
  • Min Zhao
  • Yao Zhao
  • Mei Qu
  • Yu Ke
  • Ying Liu
  • Hong-Min Liu
  • Xin Xu
  • Yanli Sun
  • Zhe-Sheng Chen
  • Zhenbo Hu
  • Mol Ther Oncolytics.2020 Sep;18:137-148. S2372-7705(20)30087-5. doi: 10.1016/j.omto.2020.06.008.Epub 2020-06-09.

高血圧症は、低酸素血症の成体ラットの血液中にインターロイキン-1βの過剰産生を誘導することにより、血液脳関門の障害を悪化させる

Hypercapnia exacerbates the disruption of the blood‑brain barrier by inducing interleukin‑1β overproduction in the blood of hypoxemic adult rats.
  • Hongguang Ding
  • Xinqiang Liu
  • Xusheng Li
  • Miaoyun Wen
  • Ya Li
  • Yongli Han
  • Linqiang Huang
  • Mengting Liu
  • Hongke Zeng
  • Int. J. Mol. Med..2020 Aug;46(2):762-772. doi: 10.3892/ijmm.2020.4604.Epub 2020-05-14.

局所進行性の咽頭下咽頭および舌底部がんに対する導入化学療法に続いて化学放射線療法を併用した場合のCCRTとの比較

Induction chemotherapy followed by concurrent chemoradiotherapy versus CCRT for locally advanced hypopharynx and base of tongue cancer.
  • Sung Hee Lim
  • Jong-Mu Sun
  • Joohyun Hong
  • Dongryul Oh
  • Yong Chan Ahn
  • Man Ki Chung
  • Han-Sin Jeong
  • Young-Ik Son
  • Myung-Ju Ahn
  • Chung-Hwan Baek
  • Keunchil Park
  • Korean J. Intern. Med..2020 Apr;kjim.2019.161. doi: 10.3904/kjim.2019.161.Epub 2020-04-03.

皮膚Aβ-非侵害受容性ではなくC-侵害受容性の背側根神経節ニューロンは、有痛性糖尿病性神経障害のストレプトゾトシンラットモデルにおける自発的な活動を示す

Cutaneous Aβ-Non-nociceptive, but Not C-Nociceptive, Dorsal Root Ganglion Neurons Exhibit Spontaneous Activity in the Streptozotocin Rat Model of Painful Diabetic Neuropathy .
  • Laiche Djouhri
  • Asad Zeidan
  • Seham A Abd El-Aleem
  • Trevor Smith
  • Front Neurosci.2020;14:530. doi: 10.3389/fnins.2020.00530.Epub 2020-05-25.

新規微生物ムラミダーゼのブロイラーニワトリへの栄養補給が消化管機能と成長能に及ぼす影響の評価

Evaluation of dietary supplementation of a novel microbial muramidase on gastrointestinal functionality and growth performance in broiler chickens.
  • Mounira Sais
  • Ana C Barroeta
  • Paola López-Colom
  • Miquel Nofrarías
  • Natàlia Majó
  • Rual Lopez-Ulibarri
  • Estefanía Pérez Calvo
  • Susana M Martín-Orúe
  • Poult. Sci..2020 Jan;99(1):235-245. S0032-5791(19)57868-3. doi: 10.3382/ps/pez466.Epub 2019-12-30.

アミロイド完全血液学的反応の精緻化：比率よりも優れた定量的血清遊離軽鎖

Refining amyloid complete hematological response: quantitative serum free light chains superior to ratio.
  • Eli Muchtar
  • Morie A Gertz
  • Martha Q Lacy
  • Nelson Leung
  • Francis K Buadi
  • David Dingli
  • Suzanne R Hayman
  • Ronald S Go
  • Prashant Kapoor
  • Wilson Gonsalves
  • Taxiarchis V Kourelis
  • Rahma Warsame
  • Yi Lisa Hwa
  • Amie Fonder
  • Miriam Hobbs
  • Stephen Russell
  • John A Lust
  • Mustaqueem Siddiqui
  • S Vincent Rajkumar
  • Robert A Kyle
  • Shaji K Kumar
  • Angela Dispenzieri
  • Am. J. Hematol..2020 Jul;doi: 10.1002/ajh.25940.Epub 2020-07-18.

抗菌・抗寄生虫剤としてのアセチル化によるチカガムの改質特性評価と生物学的性質

Modified chicha gum by acetylation for antimicrobial and antiparasitic applications: Characterization and biological properties.
  • Elton Marks Araujo Braz
  • Solranny Carla Cavalcante Costa Silva
  • Carla Adriana Rodrigues Sousa Brito
  • Fernando Aécio Amorim Carvalho
  • Michel Muálem Moraes Alves
  • Humberto Medeiros Barreto
  • Durcilene Alves Silva
  • Rui Magalhães
  • Ana Leite Oliveira
  • Edson C Silva-Filho
  • Int. J. Biol. Macromol..2020 May;S0141-8130(20)33381-X. doi: 10.1016/j.ijbiomac.2020.05.219.Epub 2020-05-29.

アジュバントされた H5N1 インフルエンザワクチンは、ヒトにおける交差反応性メモリー B 細胞および株特異的ナイーブ B 細胞応答の両方を増強する

Adjuvanted H5N1 influenza vaccine enhances both cross-reactive memory B cell and strain-specific naive B cell responses in humans.
  • Ali H Ellebedy
  • Raffael Nachbagauer
  • Katherine J L Jackson
  • Ya-Nan Dai
  • Julianna Han
  • Wafaa B Alsoussi
  • Carl W Davis
  • Daniel Stadlbauer
  • Nadine Rouphael
  • Veronika Chromikova
  • Megan McCausland
  • Cathy Y Chang
  • Mario Cortese
  • Mary Bower
  • Chakravarthy Chennareddy
  • Aaron J Schmitz
  • Veronika I Zarnitsyna
  • Lilin Lai
  • Arvind Rajabhathor
  • Cheyann Kazemian
  • Rustom Antia
  • Mark J Mulligan
  • Andrew B Ward
  • Daved H Fremont
  • Scott D Boyd
  • Bali Pulendran
  • Florian Krammer
  • Rafi Ahmed
  • Proc. Natl. Acad. Sci. U.S.A..2020 Jul;201906613. doi: 10.1073/pnas.1906613117.Epub 2020-07-13.

このように、PLTPはBAT-肝臓間コミュニケーションのメディエーターとして、全身のブドウ糖と脂質の恒常性の調節に寄与していることが示唆された

The regulation of glucose and lipid homeostasis via PLTP as a mediator of BAT-liver communication.
  • Carlos H Sponton
  • Takashi Hosono
  • Junki Taura
  • Mark P Jedrychowski
  • Takeshi Yoneshiro
  • Qiang Wang
  • Makoto Takahashi
  • Yumi Matsui
  • Kenji Ikeda
  • Yasuo Oguri
  • Kazuki Tajima
  • Kosaku Shinoda
  • Rachana N Pradhan
  • Yong Chen
  • Zachary Brown
  • Lindsay S Roberts
  • Carl C Ward
  • Hiroki Taoka
  • Yoko Yokoyama
  • Mitsuhiro Watanabe
  • Hiroshi Karasawa
  • Daniel K Nomura
  • Shingo Kajimura
  • EMBO Rep..2020 Jul;:e49828. doi: 10.15252/embr.201949828.Epub 2020-07-16.

低用量のオンコロイド性アデノウイルス療法は、腫瘍誘発性免疫抑制を克服し、抗PD-1抗体療法に対して頭蓋内グリオーマを感作する

Low-dose oncolytic adenovirus therapy overcomes tumor-induced immune suppression and sensitizes intracranial gliomas to anti-PD-1 therapy.
  • Zineb Belcaid
  • Cor Berrevoets
  • John Choi
  • Edward van Beelen
  • Eftychia Stavrakaki
  • Tessa Pierson
  • Jenneke Kloezeman
  • Denis Routkevitch
  • Mariëlle van der Kaaij
  • Alicia van der Ploeg
  • Dimitrios Mathios
  • Stefan Sleijfer
  • Clemens Dirven
  • Michael Lim
  • Reno Debets
  • Martine L M Lamfers
  • Neurooncol Adv.2020 Jan-Dec;2(1):vdaa011. vdaa011. doi: 10.1093/noajnl/vdaa011.Epub 2020-02-03.

私たちが知っていることをして、何をすべきかを知っています。乳がん予防のための科学と行動をリンクさせるカリフォルニアの人々（CLASP-BC）

Doing What We Know, Knowing What to Do: Californians Linking Action with Science for Prevention of Breast Cancer (CLASP-BC).
  • Jon F Kerner
  • Marion H E Kavanaugh-Lynch
  • Lourdes Baezconde-Garbanati
  • Christopher Politis
  • Aviva Prager
  • Ross C Brownson
  • Int J Environ Res Public Health.2020 Jul;17(14). E5050. doi: 10.3390/ijerph17145050.Epub 2020-07-14.

フィブリノーゲンは、ヒストンの細胞毒性作用から好中球を保護し、イオノマイシンによって誘導される好中球の細胞外トラップ形成を遅延させる

Fibrinogen protects neutrophils from the cytotoxic effects of histones and delays neutrophil extracellular trap formation induced by ionomycin.
  • Matthew Locke
  • Robert J Francis
  • Evgenia Tsaousi
  • Colin Longstaff
  • Sci Rep.2020 Jul;10(1):11694. 10.1038/s41598-020-68584-0. doi: 10.1038/s41598-020-68584-0.Epub 2020-07-16.

ブラジルから分離されたCryptococcus gattiiの臨床分離株および環境分離株の高い遺伝的変動性

High genetic variability of clinical and environmental Cryptococcus gattii isolates from Brazil.
  • Anderson Mançan Vilas-Bôas
  • Leonardo Euripedes Andrade-Silva
  • Kennio Ferreira-Paim
  • Delio José Mora
  • Thatiana Bragine Ferreira
  • Daniel de Assis Santos
  • Aercio Sebastião Borges
  • Marcia de Souza Carvalho Melhem
  • Mario Léon Silva-Vergara
  • Med. Mycol..2020 Apr;myaa019. doi: 10.1093/mmy/myaa019.Epub 2020-04-28.

フェンベンダゾールは、成長、ウイルス性の可能性、およびモデルの動物感染を制御する

Fenbendazole Controls Growth, Virulence Potential, and Animal Infection in the Model.
  • Haroldo C de Oliveira
  • Luna S Joffe
  • Karina S Simon
  • Rafael F Castelli
  • Flavia C G Reis
  • Arielle M Bryan
  • Beatriz S Borges
  • Lia C Soares Medeiros
  • Anamelia L Bocca
  • Maurizio Del Poeta
  • Marcio L Rodrigues
  • Antimicrob. Agents Chemother..2020 May;64(6). e00286-20. doi: 10.1128/AAC.00286-20.Epub 2020-05-21.

ブラジル、ミナスジェライス州ウロプレトの農村集団におけるNOS3およびAPOB遺伝子のバリアントと関連したチェメリンの高レベル

High levels of chemerin associated with variants in the NOS3 and APOB genes in rural populations of Ouro Preto, Minas Gerais, Brazil.
  • A P Batista
  • K F Barbosa
  • C Z Masioli
  • E M Queiroz
  • C C Marinho
  • A P C Cândido
  • G L L Machado-Coelho
  • Braz. J. Med. Biol. Res..2020;53(6):e9113. S0100-879X2020000600601. doi: 10.1590/1414-431x20209113.Epub 2020-05-08.

コロナウイルス病2019（COVID-19）：医学文献のエビデンスマップ

Coronavirus disease 2019 (COVID-19): an evidence map of medical literature.
  • Nan Liu
  • Marcel Lucas Chee
  • Chenglin Niu
  • Pin Pin Pek
  • Fahad Javaid Siddiqui
  • John Pastor Ansah
  • David Bruce Matchar
  • Sean Shao Wei Lam
  • Hairil Rizal Abdullah
  • Angelique Chan
  • Rahul Malhotra
  • Nicholas Graves
  • Mariko Siyue Koh
  • Sungwon Yoon
  • Andrew Fu Wah Ho
  • Daniel Shu Wei Ting
  • Jenny Guek Hong Low
  • Marcus Eng Hock Ong
  • BMC Med Res Methodol.2020 07;20(1):177. 10.1186/s12874-020-01059-y. doi: 10.1186/s12874-020-01059-y.Epub 2020-07-02.

ボトリオスペルマリア枯れ病に感染したブドウの品種および木部に依存するメタボロームフィンガープリント

Cultivar- and wood area-dependent metabolomic fingerprints of grapevine infected by Botryosphaeria dieback.
  • Christelle Lemaître-Guillier
  • Florence Fontaine
  • Chloé Roullier-Gall
  • Mourad Harir
  • Maryline Magnin-Robert
  • Christophe Clément
  • Sophie Trouvelot
  • Régis D Gougeon
  • Philippe Schmitt-Kopplin
  • Marielle Adrian
  • Phytopathology.2020 Jun;doi: 10.1094/PHYTO-02-20-0055-R.Epub 2020-06-29.

抗酸化物質である熟成ニンニク抽出物は、野生型および多剤耐性ヒト癌細胞に対して、ミトコンドリア透過性を変化させることで細胞毒性効果を発揮する

The antioxidant, aged garlic extract, exerts cytotoxic effects on wild-type and multidrug-resistant human cancer cells by altering mitochondrial permeability.
  • Shinji Ohkubo
  • Lisa Dalla Via
  • Silvia Grancara
  • Yuta Kanamori
  • Aída Nelly García-Argáez
  • Gianluca Canettieri
  • Paolo Arcari
  • Antonio Toninello
  • Enzo Agostinelli
  • Int. J. Oncol..2018 Sep;53(3):1257-1268. doi: 10.3892/ijo.2018.4452.Epub 2018-06-22.

マサチューセッツ州のPNQIN協同組合における新生児オピオイド離脱症候群ケアツール「食べる、眠る、コンソール」を実装するための品質改善イニシアチブ

A quality improvement initiative to implement the eat, sleep, console neonatal opioid withdrawal syndrome care tool in Massachusetts' PNQIN collaborative.
  • Elisha M Wachman
  • Mary Houghton
  • Patrice Melvin
  • Breanna C Isley
  • Jennifer Murzycki
  • Rachana Singh
  • Susan Minear
  • Kathryn Dee L MacMillan
  • Debra Banville
  • Amy Walker
  • Teresa Mitchell
  • Rose Galimi-Hayes
  • Selena Jorgensen
  • Daphne Remy Gomes
  • Fran Hodgins
  • Bonny L Whalen
  • Hafsatou Diop
  • Munish Gupta
  • J Perinatol.2020 Jul;10.1038/s41372-020-0733-y. doi: 10.1038/s41372-020-0733-y.Epub 2020-07-16.

ベッツィンガー複合体前介在ニューロンのTrpm4イオンチャネルは呼吸運動パターンには必須であるが、リズムには必須ではない

Trpm4 ion channels in pre-Bötzinger complex interneurons are essential for breathing motor pattern but not rhythm.
  • Maria Cristina D Picardo
  • Yae K Sugimura
  • Kaitlyn E Dorst
  • Prajkta S Kallurkar
  • Victoria T Akins
  • Xingru Ma
  • Ryoichi Teruyama
  • Romain Guinamard
  • Kaiwen Kam
  • Margaret S Saha
  • Christopher A Del Negro
  • PLoS Biol..2019 02;17(2):e2006094. pbio.2006094. doi: 10.1371/journal.pbio.2006094.Epub 2019-02-21.

中手骨脱臼を伴う冠状浜手骨折は2方向アプローチによる経皮的ピン止め固定を用いたヘッドレス圧縮スクリューを用いて効果的に治療した．2症例の報告

Coronal Hamate Fractures with Carpometacarpal Dislocation Treated Effectively Using Headless Compression Screws with Percutaneous Pinning Fixation by Using the 2-Directional Approach: A Report of 2 Cases.
  • Hirokazu Shimizu
  • Tomoya Matsuhashi
  • Akira Fukushima
  • Yusuke Menjo
  • Yoshihiro Hojo
  • Norimasa Iwasaki
  • JBJS Case Connect.2020 Apr-Jun;10(2):e0361. 01709767-202006000-00041. doi: 10.2106/JBJS.CC.19.00361.

治療前後のコタール症候群におけるFDG-PET：脳機能イメージングは虚無的妄想の二因子仮説を支持できるか？

FDG-PET in Cotard syndrome before and after treatment: can functional brain imaging support a two-factor hypothesis of nihilistic delusions?
  • Miguel Restrepo-Martínez
  • Mariana Espinola-Nadurille
  • Leo Bayliss
  • Ivan Díaz-Meneses
  • Nora E Kerik
  • Mario F Mendez
  • Jesús Ramírez-Bermúdez
  • Cogn Neuropsychiatry.2019 11;24(6):470-480. doi: 10.1080/13546805.2019.1676710.Epub 2019-10-09.

日本人の慢性B型肝炎ウイルス感染症治療に使用されているヌクレオス(t)イデアナログをエンテカビルからテノフォビルアラフェンアミドフマル酸塩に切り替えることの意義

Significance of switching of the nucleos(t)ide analog used to treat Japanese patients with chronic hepatitis B virus infection from entecavir to tenofovir alafenamide fumarate.
  • Yoshihito Uchida
  • Masamitsu Nakao
  • Shohei Tsuji
  • Hayato Uemura
  • Jun-Ichi Kouyama
  • Kayoko Naiki
  • Daisuke Motoya
  • Kayoko Sugawara
  • Nobuaki Nakayama
  • Yukinori Imai
  • Tomoaki Tomiya
  • Satoshi Mochida
  • J. Med. Virol..2020 Aug;92(8):1370. doi: 10.1002/jmv.25837.Epub 2020-04-17.

妊娠中の予防接種に関する世界的な展望と今後の研究開発のための優先事項。国際的なコンセンサス・ステートメント

Global Perspectives on Immunization During Pregnancy and Priorities for Future Research and Development: An International Consensus Statement.
  • Bahaa Abu-Raya
  • Kirsten Maertens
  • Kathryn M Edwards
  • Saad B Omer
  • Janet A Englund
  • Katie L Flanagan
  • Matthew D Snape
  • Gayatri Amirthalingam
  • Elke Leuridan
  • Pierre Van Damme
  • Vana Papaevangelou
  • Odile Launay
  • Ron Dagan
  • Magda Campins
  • Anna Franca Cavaliere
  • Tiziana Frusca
  • Sofia Guidi
  • Miguel O'Ryan
  • Ulrich Heininger
  • Tina Tan
  • Ahmed R Alsuwaidi
  • Marco A Safadi
  • Luz M Vilca
  • Nasamon Wanlapakorn
  • Shabir A Madhi
  • Michelle L Giles
  • Roman Prymula
  • Shamez Ladhani
  • Federico Martinón-Torres
  • Litjen Tan
  • Lessandra Michelin
  • Giovanni Scambia
  • Nicola Principi
  • Susanna Esposito
  • Front Immunol.2020;11:1282. doi: 10.3389/fimmu.2020.01282.Epub 2020-06-24.

膀胱扁平上皮癌は高リスクのHPVと関連していない

Squamous Cell Carcinoma of the Bladder is Not Associated with High-Risk HPV.
  • Jennifer Gordetsky
  • Andrew J Spieker
  • Maria Del Carmen Rodriguez Pena
  • Sonia Kamanda
  • Michele R Anderson
  • John Cheville
  • Steve Boorjian
  • Igor Frank
  • Carlos Prieto Granada
  • Eva Comperat
  • Michelle S Hirsch
  • Kenneth A Iczkowski
  • Brittney Imblum
  • Lauren Schwartz
  • Giovanna A Giannico
  • Soroush Rais-Bahrami
  • Urology.2020 Jul;S0090-4295(20)30832-3. doi: 10.1016/j.urology.2020.06.065.Epub 2020-07-15.

オーストラリアのダーウィン地域におけるキネトプラスティダ（Kinetoplastida: Trypanosomatidae）の媒介者と疑われる() (Diptera: Ceratopogonidae)の種を、新しいサーベイランスシステムを用いて調査した

Utilising a novel surveillance system to investigate species of () (Diptera: Ceratopogonidae) as the suspected vectors of (Kinetoplastida: Trypanosomatidae) in the Darwin region of Australia.
  • Elina Panahi
  • Martin Shivas
  • Sonja Hall-Mendelin
  • Nina Kurucz
  • Penny A Rudd
  • Rachel De Araujo
  • Eloise B Skinner
  • Lorna Melville
  • Lara J Herrero
  • Int J Parasitol Parasites Wildl.2020 Aug;12:192-198. S2213-2244(20)30060-2. doi: 10.1016/j.ijppaw.2020.06.004.Epub 2020-06-17.

S-メチル-L-システインは、内因性メチオニンを中心としたレドックスサイクルを模倣することにより、神経細胞のアンチマイシンA誘発ミトコンドリア障害を防御することを明らかにした

S-methyl-L-cysteine Protects against Antimycin A-induced Mitochondrial Dysfunction in Neural Cells via Mimicking Endogenous Methionine-centered Redox Cycle.
  • Lan Ni
  • Xin-Lei Guan
  • Fu-Feng Chen
  • Peng-Fei Wu
  • Curr Med Sci.2020 Jun;40(3):422-433. 10.1007/s11596-020-2196-y. doi: 10.1007/s11596-020-2196-y.Epub 2020-07-17.

LPAR1トラフィッキングのN-WASP制御は、膵臓癌細胞の転移を促進するために自己生成されたLPA勾配への応答を確立する

N-WASP Control of LPAR1 Trafficking Establishes Response to Self-Generated LPA Gradients to Promote Pancreatic Cancer Cell Metastasis.
  • Amelie Juin
  • Heather J Spence
  • Kirsty J Martin
  • Ewan McGhee
  • Matthew Neilson
  • Marie F A Cutiongco
  • Nikolaj Gadegaard
  • Gillian Mackay
  • Loic Fort
  • Sergio Lilla
  • Gabriela Kalna
  • Peter Thomason
  • Yvette W H Koh
  • Jim C Norman
  • Robert H Insall
  • Laura M Machesky
  • Dev. Cell.2019 11;51(4):431-445.e7. S1534-5807(19)30774-9. doi: 10.1016/j.devcel.2019.09.018.Epub 2019-10-24.

核内でコードされたDREB転写因子によるミトコンドリアorf355遺伝子発現の活性化は、トウモロコシの細胞質性雄性不稔を引き起こす

Activation of Mitochondrial orf355 Gene Expression by A Nuclear-Encoded DREB Transcription Factor Causes Cytoplasmic Male Sterility in Maize.
  • Senlin Xiao
  • Jie Zang
  • Yuanrong Pei
  • Jie Liu
  • Juan Liu
  • Wei Song
  • Zi Shi
  • Aiguo Su
  • Jiuran Zhao
  • Huabang Chen
  • Mol Plant.2020 Jul;S1674-2052(20)30215-X. doi: 10.1016/j.molp.2020.07.002.Epub 2020-07-03.

土壌中の揮発性多環芳香族炭化水素の定量のためのHPLCと結合した充填吸着剤による冷却支援型ヘッドスペースマイクロ抽出法（HS-MEPS）を開発した

Cooling assisted headspace microextraction by packed sorbent coupled to HPLC for the determination of volatile polycyclic aromatic hydrocarbons in soil.
  • Fariba Nazari Serenjeh
  • Payman Hashemi
  • Ali Reza Ghiasvand
  • Fahimeh Rasolzadeh
  • Nahid Heydari
  • Alireza Badiei
  • Anal. Chim. Acta.2020 Aug;1125:128-134. S0003-2670(20)30625-5. doi: 10.1016/j.aca.2020.05.067.Epub 2020-05-29.

グローバル髄膜炎ゲノムパートナーシップ

The global meningitis genome partnership.
  • Elizabeth Rodgers
  • Stephen D Bentley
  • Ray Borrow
  • Holly B Bratcher
  • Sylvain Brisse
  • Angela B Brueggemann
  • Dominique A Caugant
  • Jamie Findlow
  • LeAnne Fox
  • Linda Glennie
  • Lee H Harrison
  • Odile B Harrison
  • Robert S Heyderman
  • Melissa Jansen van Rensburg
  • Keith A Jolley
  • Brenda Kwambana-Adams
  • Shamez Ladhani
  • Marc LaForce
  • Michael Levin
  • Jay Lucidarme
  • Neil MacAlasdair
  • Jenny Maclennan
  • Martin C J Maiden
  • Laura Maynard-Smith
  • Alessandro Muzzi
  • Philipp Oster
  • Charlene M C Rodrigues
  • Olivier Ronveaux
  • Laura Serino
  • Vinny Smith
  • Arie van der Ende
  • Julio Vázquez
  • Xin Wang
  • Saber Yezli
  • James M Stuart
  • J. Infect..2020 Jun;S0163-4453(20)30446-1. doi: 10.1016/j.jinf.2020.06.064.Epub 2020-06-29.

cusatuzumabでCD70を標的とすることで、低メチル化剤で治療された患者の急性骨髄性白血病幹細胞が排除される

Targeting CD70 with cusatuzumab eliminates acute myeloid leukemia stem cells in patients treated with hypomethylating agents.
  • Carsten Riether
  • Thomas Pabst
  • Sabine Höpner
  • Ulrike Bacher
  • Magdalena Hinterbrandner
  • Yara Banz
  • Rouven Müller
  • Markus G Manz
  • Walid H Gharib
  • David Francisco
  • Remy Bruggmann
  • Luc van Rompaey
  • Mahan Moshir
  • Tim Delahaye
  • Domenica Gandini
  • Ellen Erzeel
  • Anna Hultberg
  • Samson Fung
  • Hans de Haard
  • Nicolas Leupin
  • Adrian F Ochsenbein
  • Nat. Med..2020 Jun;10.1038/s41591-020-0910-8. doi: 10.1038/s41591-020-0910-8.Epub 2020-06-29.

HIV-1 自然感染および RV114 ワクチン試験における Fc 媒介応答に関与する C1/C2 エピトープの認識パターン

Recognition Patterns of the C1/C2 Epitopes Involved in Fc-Mediated Response in HIV-1 Natural Infection and the RV114 Vaccine Trial.
  • William D Tolbert
  • Verna Van
  • Rebekah Sherburn
  • Marina Tuyishime
  • Fang Yan
  • Dung N Nguyen
  • Sherry Stanfield-Oakley
  • David Easterhoff
  • Mattia Bonsignori
  • Barton F Haynes
  • M Anthony Moody
  • Krishanu Ray
  • Guido Ferrari
  • George K Lewis
  • Marzena Pazgier
  • mBio.2020 Jun;11(3). e00208-20. doi: 10.1128/mBio.00208-20.Epub 2020-06-30.

繊毛化ヒト鼻上皮細胞における細胞内Clによって制御された繊毛拍動振幅と高率のCO産生

Ciliary beating amplitude controlled by intracellular Cl and a high rate of CO production in ciliated human nasal epithelial cells.
  • Taka-Aki Inui
  • Kentaro Murakami
  • Makoto Yasuda
  • Shigeru Hirano
  • Yukiko Ikeuchi
  • Haruka Kogiso
  • Shigekuni Hosogi
  • Toshio Inui
  • Yoshinori Marunaka
  • Takashi Nakahari
  • Pflugers Arch..2019 08;471(8):1127-1142. 10.1007/s00424-019-02280-5. doi: 10.1007/s00424-019-02280-5.Epub 2019-05-18.

オリーブのバイオマスをベースにした高表面積活性炭へのアモキシシリンの吸着：速度論的・平衡論的研究

Adsorption of amoxicillin onto high surface area-activated carbons based on olive biomass: kinetic and equilibrium studies.
  • Daniel Lucas Costa Rodrigues
  • Fernando Machado Machado
  • Alice Gonçalves Osório
  • Cristiane Ferraz de Azevedo
  • Eder Claudio Lima
  • Raphaelle S da Silva
  • Diana Ramos Lima
  • Fernanda Medeiros Gonçalves
  • Environ Sci Pollut Res Int.2020 Jul;10.1007/s11356-020-09583-6. doi: 10.1007/s11356-020-09583-6.Epub 2020-07-18.

インドネシアの蚊から分離された蚊媒介ウイルス、昆虫特異的フラビウイルス（フラビウイルス科、フラビウイルス属）、Bannaウイルス（Reoviridae科、Seadornavirus属）、Bogorウイルス（Permutotetraviridae科の未分類メンバー）、およびalphamesoniviruses 2および3（Mesoniviridae科、Alphamesonivirus属）を用いて、蚊が媒介するウイルスを調査した

Mosquito-borne viruses, insect-specific flaviviruses (family Flaviviridae, genus Flavivirus), Banna virus (family Reoviridae, genus Seadornavirus), Bogor virus (unassigned member of family Permutotetraviridae), and alphamesoniviruses 2 and 3 (family Mesoniviridae, genus Alphamesonivirus) isolated from Indonesian mosquitoes.
  • Ryusei Kuwata
  • Shun Torii
  • Hiroshi Shimoda
  • Keita Ishijima
  • Kenzo Yonemitsu
  • Shohei Minami
  • Yudai Kuroda
  • Kango Tatemoto
  • Ngo Thuy Bao Tran
  • Ai Takano
  • Tsutomu Omatsu
  • Tetsuya Mizutani
  • Kentaro Itokawa
  • Haruhiko Isawa
  • Kyoko Sawabe
  • Tomohiko Takasaki
  • Dewi Maria Yuliani
  • Dimas Abiyoga
  • Upik Kesumawati Hadi
  • Agus Setiyono
  • Eiichi Hondo
  • Srihadi Agungpriyono
  • Ken Maeda
  • J. Vet. Med. Sci..2020 May;doi: 10.1292/jvms.20-0261.Epub 2020-05-25.

ニコチンは若年成人ラットのマイトファジークリアランスを阻害することで心毒性を誘導する

Nicotine induces cardiac toxicity through blocking mitophagic clearance in young adult rat.
  • Guizhi Jia
  • Zhijun Meng
  • Caihong Liu
  • Xinliang Ma
  • Jia Gao
  • Jing Liu
  • Rui Guo
  • Zheyi Yan
  • Theodore Christopher
  • Bernard Lopez
  • Wenxia Liu
  • Hongliang Dai
  • Wayne Bond Lau
  • Xiangying Jiao
  • Jianli Zhao
  • Zi-Xuan Wang
  • Jimin Cao
  • Yajing Wang
  • Life Sci..2020 Jul;:118084. S0024-3205(20)30835-3. doi: 10.1016/j.lfs.2020.118084.Epub 2020-07-11.

治療的中絶と子宮外妊娠：イスラム国イランにおける胎児幹細胞研究と治療の代替ソース

Therapeutic abortion and ectopic pregnancy: alternative sources for fetal stem cell research and therapy in Iran as an Islamic country.
  • Parisa Goodarzi
  • Khadijeh Falahzadeh
  • Hamidreza Aghayan
  • Moloud Payab
  • Bagher Larijani
  • Sepideh Alavi-Moghadam
  • Akram Tayanloo-Beik
  • Hossein Adibi
  • Kambiz Gilany
  • Babak Arjmand
  • Cell Tissue Bank.2019 Mar;20(1):11-24. 10.1007/s10561-018-9741-y. doi: 10.1007/s10561-018-9741-y.Epub 2018-12-07.

黄色ブドウ球菌バイオフィルムによる乳酸産生は、持続感染時に宿主免疫応答を再プログラムするHDAC11を阻害する

Lactate production by Staphylococcus aureus biofilm inhibits HDAC11 to reprogramme the host immune response during persistent infection.
  • Cortney E Heim
  • Megan E Bosch
  • Kelsey J Yamada
  • Amy L Aldrich
  • Sujata S Chaudhari
  • David Klinkebiel
  • Casey M Gries
  • Abdulelah A Alqarzaee
  • Yixuan Li
  • Vinai C Thomas
  • Edward Seto
  • Adam R Karpf
  • Tammy Kielian
  • Nat Microbiol.2020 Jul;10.1038/s41564-020-0756-3. doi: 10.1038/s41564-020-0756-3.Epub 2020-07-13.

その結果、三酸化ヒ素と BIBR1532 は、NF-κB シグナル伝達経路の減衰を介して乳がん細胞の増殖を相乗的に抑制することが確認されました

Arsenic trioxide and BIBR1532 synergistically inhibit breast cancer cell proliferation through attenuation of NF-κB signaling pathway.
  • Ali Nasrollahzadeh
  • Davood Bashash
  • Majid Kabuli
  • Zahra Zandi
  • Bahahreh Kashani
  • Azam Zaghal
  • Seyed A Mousavi
  • Seyed H Ghaffari
  • Life Sci..2020 Jul;:118060. S0024-3205(20)30811-0. doi: 10.1016/j.lfs.2020.118060.Epub 2020-07-06.

ビフェントリンとアセトクロルの二種類の組み合わせに曝露した胚-幼体ゼブラフィッシュにおける甲状腺ホルモンレベルと関連遺伝子発現の変化

Changes in thyroid hormone levels and related gene expressions in embryo-larval zebrafish exposed to binary combinations of bifenthrin and acetochlor.
  • Dongmei Guo
  • Wenping Liu
  • Jing Qiu
  • Yun Li
  • Liezong Chen
  • Shenggan Wu
  • Qiang Wang
  • Yongzhong Qian
  • Ecotoxicology.2020 Jul;29(5):584-593. 10.1007/s10646-020-02206-3. doi: 10.1007/s10646-020-02206-3.Epub 2020-05-28.

高麗紅参は、エストロゲン受容体βや脳由来の神経栄養因子のアップレギュレーションを介して酸化ストレスを抑制することで、間欠的な熱ストレスを受けたラット脳の神経炎症を緩和し、細胞の生存を促進します

Korean Red Ginseng alleviates neuroinflammation and promotes cell survival in the intermittent heat stress-induced rat brain by suppressing oxidative stress via estrogen receptor beta and brain-derived neurotrophic factor upregulation.
  • Hamid Iqbal
  • Si-Kwan Kim
  • Kyu-Min Cha
  • Min-Sik Jeong
  • Prachetash Ghosh
  • Dong-Kwon Rhee
  • J Ginseng Res.2020 Jul;44(4):593-602. S1226-8453(19)30012-0. doi: 10.1016/j.jgr.2019.05.007.Epub 2019-05-24.

低酸素およびミトコンドリア呼吸阻害剤によるスクイコチリエート寄生虫のオルタナティブオキシダーゼの分子特性と遺伝子発現の調節

Molecular characterization and gene expression modulation of the alternative oxidase in a scuticociliate parasite by hypoxia and mitochondrial respiration inhibitors.
  • Iría Folgueira
  • Jesús Lamas
  • Rosa Ana Sueiro
  • José Manuel Leiro
  • Sci Rep.2020 Jul;10(1):11880. 10.1038/s41598-020-68791-9. doi: 10.1038/s41598-020-68791-9.Epub 2020-07-17.

妊娠初期に子豚にアルギニンを補給すると、豚のコンセプテーゼのエネルギー感受性経路に影響を与えます

l-Arginine supplementation of gilts during early gestation modulates energy sensitive pathways in pig conceptuses.
  • Ingrid S Garcia
  • Susana A Teixeira
  • Karine A Costa
  • Daniele B D Marques
  • Gustavo de A Rodrigues
  • Thaís C Costa
  • José D Guimarães
  • Pamela I Otto
  • Alysson Saraiva
  • Adriana M G Ibelli
  • Maurício E Cantão
  • Haniel C de Oliveira
  • Mônica C Ledur
  • Jane de O Peixoto
  • Simone E F Guimarães
  • Mol. Reprod. Dev..2020 Jun;doi: 10.1002/mrd.23397.Epub 2020-06-27.

抗レトロウイルス管理のためのミトコンドリアトキシコゲノミクス。未感染患者におけるHIV曝露後の予防

Mitochondrial Toxicogenomics for Antiretroviral Management: HIV Post-exposure Prophylaxis in Uninfected Patients.
  • Maria Bañó
  • Constanza Morén
  • Sergio Barroso
  • Diana Luz Juárez
  • Mariona Guitart-Mampel
  • Ingrid González-Casacuberta
  • Judith Canto-Santos
  • Ester Lozano
  • Agathe León
  • Enric Pedrol
  • Òscar Miró
  • Ester Tobías
  • Josep Mallolas
  • Jhon F Rojas
  • Francesc Cardellach
  • Esteban Martínez
  • Gloria Garrabou
  • Front Genet.2020;11:497. doi: 10.3389/fgene.2020.00497.Epub 2020-05-26.

ピペリンアルカロイドは、G2/M期の細胞周期停止、カスパーゼ活性化、細胞遊走阻害、PI3K/Akt/GSK3βシグナル伝達経路の阻害により、シスプラチン抵抗性卵巣癌において抗癌作用、アポトーシス作用を誘導する

Piperine alkaloid induces anticancer and apoptotic effects in cisplatin resistant ovarian carcinoma by inducing G2/M phase cell cycle arrest, caspase activation and inhibition of cell migration and PI3K/Akt/GSK3β signalling pathway.
  • Min Qiu
  • Chunyan Xue
  • Lingyan Zhang
  • J BUON.2019 Nov-Dec;24(6):2316-2321.

コイ医科大学の学生における月経前症候群の酸化ストレスマーカーに及ぼすベンソン・リラクセーションの影響

The Influence of Benson Relaxation on Oxidative Stress Marker of Premenstrual Syndrome in Students of Khoy University of Medical Sciences.
  • Jalhe Bagheri Hamzyan Olia
  • Soryya Zinalpoor
  • Shahriar Sakhaei
  • Hassan Ebrahimpour Sadagheyani
  • Hossein Motaarefi
  • Open Access Maced J Med Sci.2019 Dec;7(23):4149-4154. OAMJMS-7-4149. doi: 10.3889/oamjms.2019.865.Epub 2019-12-10.

成人における在宅経腸栄養-全国多施設調査．

Home Enteral Nutrition in Adults-Nationwide Multicenter Survey.
  • Marcin Folwarski
  • Stanisław Kłęk
  • Agata Zoubek-Wójcik
  • Waldemar Szafrański
  • Lidia Bartoszewska
  • Krzysztof Figuła
  • Marlena Jakubczyk
  • Anna Jurczuk
  • Zbigniew Kamocki
  • Karolina Kaźmierczak-Siedlecka
  • Tomasz Kowalczyk
  • Bogna Kwella
  • Przemysław Matras
  • Karolina Skonieczna-Żydecka
  • Joanna Sonsala-Wołczyk
  • Jacek Szopiński
  • Krystyna Urbanowicz
  • Anna Zmarzły
  • Nutrients.2020 Jul;12(7). E2087. doi: 10.3390/nu12072087.Epub 2020-07-14.

ロッド特異的なDHDDSアブレーションによって引き起こされる網膜変性は、タンパク質のN-グリコシル化の同時阻害なしに発生します

Retinal Degeneration Caused by Rod-Specific Dhdds Ablation Occurs without Concomitant Inhibition of Protein N-Glycosylation.
  • Sriganesh Ramachandra Rao
  • Lara A Skelton
  • Fuguo Wu
  • Agnieszka Onysk
  • Grzegorz Spolnik
  • Witold Danikiewicz
  • Mark C Butler
  • Delores A Stacks
  • Liliana Surmacz
  • Xiuqian Mu
  • Ewa Swiezewska
  • Steven J Pittler
  • Steven J Fliesler
  • iScience.2020 Jun;23(6):101198. S2589-0042(20)30383-7. doi: 10.1016/j.isci.2020.101198.Epub 2020-05-23.

次亜塩素酸カルシウムの過酢酸と活性塩素の致死濃度と亜致死濃度の影響

Effects of lethal and sublethal concentrations of peracetic acid and active chlorine of calcium hypochlorite on Chironomus xanthus.
  • Luana Priscilla Rodrigues Macêdo
  • Aline Silvestre Pereira Dornelas
  • Mayane Marques Vieira
  • Joel Santiago de Jesus Ferreira
  • Renato Almeida Sarmento
  • Grasiele Soares Cavallini
  • Chemosphere.2020 Oct;256:127171. S0045-6535(20)31364-3. doi: 10.1016/j.chemosphere.2020.127171.Epub 2020-05-23.

下顎切開管の有病率と形態．コーンビームコンピュータ断層撮影を用いた北京地区の人口における健康な大あご、歯周炎、無歯顎の比較

Prevalence and Morphology of Mandibular Incisive Canal: Comparison among Healthy, Periodontitis and Edentulous Mandibles in a Population of the Beijing Area Using Cone-beam Computed Tomography.
  • Ya Qiong Zhang
  • Xue Bing Yan
  • Li Qi Zhang
  • Xiao Yan Xie
  • Deng Gao Liu
  • Zu Yan Zhang
  • Chin J Dent Res.2019;22(4):241-249. 43735. doi: 10.3290/j.cjdr.a43735.

トウモロコシワラとキャベツ廃棄物の共エンサイリングシステムの発酵特性と微生物群集の多様性に及ぼす季節温度の違いの影響

Effects of different simulated seasonal temperatures on the fermentation characteristics and microbial community diversities of the maize straw and cabbage waste co-ensiling system.
  • Haiwei Ren
  • Yinping Feng
  • Tong Liu
  • Jinping Li
  • Zhiye Wang
  • Shanfei Fu
  • Yi Zheng
  • Zhangpu Peng
  • Sci. Total Environ..2020 Mar;708:135113. S0048-9697(19)35105-8. doi: 10.1016/j.scitotenv.2019.135113.Epub 2019-11-22.

腎移植患者におけるファーマコゲノミクスと実践への統合の可能性

Pharmacogenomics in kidney transplant recipients and potential for integration into practice.
  • Tam T Nguyen
  • Rachael A Pearson
  • Moataz E Mohamed
  • David P Schladt
  • Danielle Berglund
  • Zachary Rivers
  • Debra J Skaar
  • Baolin Wu
  • Weihua Guan
  • Jessica van Setten
  • Brendan J Keating
  • Casey Dorr
  • Rory P Remmel
  • Arthur J Matas
  • Roslyn B Mannon
  • Ajay K Israni
  • William S Oetting
  • Pamala A Jacobson
  • J Clin Pharm Ther.2020 Jul;doi: 10.1111/jcpt.13223.Epub 2020-07-14.

同一環境下で飼育された寄生虫の子鳥と宿主の子鳥の腸内細菌叢：遺伝的影響と環境的影響の切り分け

The gut microbiota of brood parasite and host nestlings reared within the same environment: disentangling genetic and environmental effects.
  • Chop Yan Lee
  • Juan Manuel Peralta-Sánchez
  • Manuel Martínez-Bueno
  • Anders Pape Møller
  • Miguel Rabelo-Ruiz
  • Carmen Zamora-Muñoz
  • Juan José Soler
  • ISME J.2020 Jul;10.1038/s41396-020-0719-y. doi: 10.1038/s41396-020-0719-y.Epub 2020-07-17.

ケタミンの持続的な抗うつ活性には、皮質およびラッパのGABA、AMPA受容体およびグリアGLT-1グルタミン酸トランスポーターが寄与しています

Cortical and raphe GABA, AMPA receptors and glial GLT-1 glutamate transporter contribute to the sustained antidepressant activity of ketamine.
  • Thu Ha Pham
  • Céline Defaix
  • Thi Mai Loan Nguyen
  • Indira Mendez-David
  • Laurent Tritschler
  • Denis J David
  • Alain M Gardier
  • Pharmacol. Biochem. Behav..2020 05;192:172913. S0091-3057(19)30648-3. doi: 10.1016/j.pbb.2020.172913.Epub 2020-03-20.

オーストラリアの早産児集団における重度未熟児網膜症（ROP）を同定するためのWINROP（オンライン予測モデル）の検証：レトロスペクティブ研究

Validation of WINROP (online prediction model) to identify severe retinopathy of prematurity (ROP) in an Australian preterm population: a retrospective study.
  • Saumil Desai
  • Sam E Athikarisamy
  • Pia Lundgren
  • Karen Simmer
  • Geoffrey C Lam
  • Eye (Lond).2020 Jul;10.1038/s41433-020-1094-7. doi: 10.1038/s41433-020-1094-7.Epub 2020-07-17.

Mfn2とIREαの相互作用を介したフェロプトーシスはヒ素誘発性非アルコール性脂肪肝炎を促進する

Ferroptosis mediated by the interaction between Mfn2 and IREα promotes arsenic-induced nonalcoholic steatohepatitis.
  • Sen Wei
  • Tianming Qiu
  • Ningning Wang
  • Xiaofeng Yao
  • Liping Jiang
  • Xue Jia
  • Ye Tao
  • Jingyuan Zhang
  • Yuhan Zhu
  • Guang Yang
  • Xiaofang Liu
  • Shuang Liu
  • Xiance Sun
  • Environ. Res..2020 Jun;188:109824. S0013-9351(20)30719-2. doi: 10.1016/j.envres.2020.109824.Epub 2020-06-23.

タクロリムスは、ナトリウム-カリウム-2塩化物コトランスポーターとナトリウム-塩化物コトランスポーターの活性化を介して、4型バルター症候群モデルマウスの表現型を改善する

Tacrolimus ameliorates the phenotypes of type 4 Bartter syndrome model mice through activation of sodium-potassium-2 chloride cotransporter and sodium-chloride cotransporter.
  • Yoshiaki Matsuura
  • Naohiro Nomura
  • Wakana Shoda
  • Takayasu Mori
  • Kiyoshi Isobe
  • Koichiro Susa
  • Fumiaki Ando
  • Eisei Sohara
  • Tatemitsu Rai
  • Shinichi Uchida
  • Biochem. Biophys. Res. Commun..2019 09;517(2):364-368. S0006-291X(19)31440-8. doi: 10.1016/j.bbrc.2019.07.086.Epub 2019-07-27.

シリカナノ粒子をマウスに単回静脈内投与した場合の1年間の慢性毒性評価とそのEx vivoヒト血液適合性

One-year chronic toxicity evaluation of single dose intravenously administered silica nanoparticles in mice and their Ex vivo human hemocompatibility.
  • Raziye Mohammadpour
  • Darwin L Cheney
  • Jason W Grunberger
  • Mostafa Yazdimamaghani
  • Jolanta Jedrzkiewicz
  • Kyle J Isaacson
  • Marina A Dobrovolskaia
  • Hamidreza Ghandehari
  • J Control Release.2020 May;324:471-481. S0168-3659(20)30304-7. doi: 10.1016/j.jconrel.2020.05.027.Epub 2020-05-25.

心臓弁手術後の成人患者におけるせん妄に対する術中デクスメデトミジン点滴の効果：無作為化二重盲検プラセボ対照試験のプロトコール

Effect of intraoperative dexmedetomidine infusion on delirium in adult patients following cardiac valve surgery: a protocol of a randomized, double-blinded, and placebo-controlled study.
  • Hong-Bai Wang
  • Liang Zhang
  • Zhe Zhang
  • Su Yuan
  • Fu-Xia Yan
  • Qi-Peng Luo
  • Trials.2020 Jul;21(1):645. 10.1186/s13063-020-04574-x. doi: 10.1186/s13063-020-04574-x.Epub 2020-07-14.

インドール産生の阻害は、大腸菌ペルシスターに対するキノロン系抗生物質の活性を高める

Inhibition of indole production increases the activity of quinolone antibiotics against E. coli persisters.
  • Ashraf Zarkan
  • Marta Matuszewska
  • Stephen B Trigg
  • Meng Zhang
  • Daaniyah Belgami
  • Cameron Croft
  • Junyan Liu
  • Sawssen El-Ouisi
  • Jack Greenhalgh
  • James S Duboff
  • Taufiq Rahman
  • David K Summers
  • Sci Rep.2020 Jul;10(1):11742. 10.1038/s41598-020-68693-w. doi: 10.1038/s41598-020-68693-w.Epub 2020-07-16.

受精治療を受けている多嚢胞性卵巣症候群患者で卵巣刺激に過剰反応または過少反応した患者におけるレスキュー成熟。有効な選択肢か？症例シリーズ研究

Rescue Maturation in Polycystic Ovarian Syndrome Patients Undergoing Fertilization Treatment who Overrespond or Underrespond to Ovarian Stimulation: Is It A Viable Option? A Case Series Study.
  • Muhammad Fatum
  • Marie Eve Bergeron
  • Caroline Ross
  • Anni Ding
  • Ayesha Bhevan
  • Karen Turner
  • Tim Child
  • Int J Fertil Steril.2020 Jul;14(2):137-142. doi: 10.22074/ijfs.2020.6025.Epub 2020-07-15.

ミツバチ（A. mellifera）における急性接触毒性と作用モードのプロファイリングを予測するQSARモデルの統合。オープンソースデータベースを用いたデータキュレーション、性能試験、バリデーション

Integrating QSAR models predicting acute contact toxicity and mode of action profiling in honey bees (A. mellifera): Data curation using open source databases, performance testing and validation.
  • Edoardo Carnesecchi
  • Cosimo Toma
  • Alessandra Roncaglioni
  • Nynke Kramer
  • Emilio Benfenati
  • Jean Lou C M Dorne
  • Sci. Total Environ..2020 Sep;735:139243. S0048-9697(20)32760-1. doi: 10.1016/j.scitotenv.2020.139243.Epub 2020-05-17.

重症のCOVID-19患者は、SARS-CoV-2に反応するCD8 T細胞の機能特性が増強されていることを示した

Severely ill COVID-19 patients display augmented functional properties in SARS-CoV-2-reactive CD8 T cells.
  • Anthony Kusnadi
  • Ciro Ramírez-Suástegui
  • Vicente Fajardo
  • Serena J Chee
  • Benjamin J Meckiff
  • Hayley Simon
  • Emanuela Pelosi
  • Grégory Seumois
  • Ferhat Ay
  • Pandurangan Vijayanand
  • Christian H Ottensmeier
  • bioRxiv.2020 Jul;2020.07.09.194027. doi: 10.1101/2020.07.09.194027.Epub 2020-07-10.

間葉系間葉系間質細胞からのインスリン産生細胞。糖尿病ラットの認知機能障害に対する保護はインプラント部位に依存する

Insulin-producing cells from mesenchymal stromal cells: Protection against cognitive impairment in diabetic rats depends upon implant site.
  • Krista Minéia Wartchow
  • Leticia Rodrigues
  • Lílian Juliana Lissner
  • Barbara Carolina Federhen
  • Nicholas Guerini Selistre
  • Aline Moreira
  • Carlos-Alberto Gonçalves
  • Patrícia Sesterheim
  • Life Sci..2020 Jun;251:117587. S0024-3205(20)30335-0. doi: 10.1016/j.lfs.2020.117587.Epub 2020-03-26.

急性大動脈解離に対する緊急手術を受けた八重体患者の輸血特性と止血状態：レトロスペクティブ研究

Transfusion characteristics and hemostatic conditions in octogenarians undergoing emergency surgery for acute aortic dissection: a retrospective study.
  • Tetsuhito Masubuchi
  • Kenji Yoshitani
  • Kimito Minami
  • Chisaki Yokoyama
  • Akito Tsukinaga
  • Takahisa Goto
  • Yoshihiko Ohnishi
  • JA Clin Rep.2020 Jul;6(1):52. 10.1186/s40981-020-00358-z. doi: 10.1186/s40981-020-00358-z.Epub 2020-07-09.

ヒト子宮頸がんHeLa株における細菌性シクロジペプチドの抗増殖効果は、TSC1/2依存的にmTORC1/C2複合体を阻害するなど、複数のプロテインキナーゼを標的としていることが明らかになった

Antiproliferative effect of bacterial cyclodipeptides in the HeLa line of human cervical cancer reveals multiple protein kinase targeting, including mTORC1/C2 complex inhibition in a TSC1/2-dependent manner.
  • Laura Hernández-Padilla
  • Homero Reyes de la Cruz
  • Jesús Campos-García
  • Apoptosis.2020 Jul;10.1007/s10495-020-01619-z. doi: 10.1007/s10495-020-01619-z.Epub 2020-07-02.

COVID-19パンデミック時の外傷患者の初期トリアージにおけるPCRスクリーニングの有用性

Usefulness of PCR screening in the initial triage of trauma patients during COVID-19 pandemic.
  • Juan Antonio Porcel-Vazquez
  • Jose Vicente Andres-Peiro
  • Yaiza Garcia-Sanchez
  • Ernesto Guerra-Farfan
  • Jaume Mestre-Torres
  • Joan Minguell-Monyart
  • Vicente Molero-Garcia
  • Jordi Selga Marsa
  • Jordi Tomas-Hernandez
  • Maria Del Mar Villar-Casares
  • Mohit Bhandari
  • Jordi Teixidor-Serra
  • J Orthop Trauma.2020 Jul;doi: 10.1097/BOT.0000000000001903.Epub 2020-07-13.

サンゴのMontastraea cavernosaとMussismilia braziliensisに関連した系統的に多様な共生細菌の保存された色素プロファイル

Conserved Pigment Profiles in Phylogenetically Diverse Symbiotic Bacteria Associated with the Corals Montastraea cavernosa and Mussismilia braziliensis.
  • Tooba Varasteh
  • Lidilhone Hamerski
  • Diogo Tschoeke
  • Arthur Silva Lima
  • Gizele Garcia
  • Carlos Alberto Nunes Cosenza
  • Cristiane Thompson
  • Fabiano Thompson
  • Microb. Ecol..2020 Jul;10.1007/s00248-020-01551-4. doi: 10.1007/s00248-020-01551-4.Epub 2020-07-18.

急性低酸素血症性呼吸不全および急性呼吸窮迫症候群患者における死亡の原因と特徴：レトロスペクティブコホート研究

Causes and characteristics of death in patients with acute hypoxemic respiratory failure and acute respiratory distress syndrome: a retrospective cohort study.
  • Scott W Ketcham
  • Yub Raj Sedhai
  • H Catherine Miller
  • Thomas C Bolig
  • Amy Ludwig
  • Ivan Co
  • Dru Claar
  • Jakob I McSparron
  • Hallie C Prescott
  • Michael W Sjoding
  • Crit Care.2020 07;24(1):391. 10.1186/s13054-020-03108-w. doi: 10.1186/s13054-020-03108-w.Epub 2020-07-03.

エピネフリンでメラニン化したクリプトコッカス・ネオフォルマン/クリプトコッカス・ガッティイ種複合体。アンホテリシンB曝露後の酵母生存率の上昇

Cryptococcus neoformans/Cryptococcus gattii species complex melanized by epinephrine: Increased yeast survival after amphotericin B exposure.
  • Raimunda Sâmia Norgueira Brilhante
  • Maria Gleiciane da Rocha
  • Jonathas Sales de Oliveira
  • Waldemiro Aquino Pereira-Neto
  • Glaucia Morgana de Melo Guedes
  • Rossana de Aguiar Cordeiro
  • José Júlio Costa Sidrim
  • Marcos Fábio Gadelha Rocha
  • Débora de Souza Collares Maia Castelo-Branco
  • Microb. Pathog..2020 Jun;143:104123. S0882-4010(20)30410-1. doi: 10.1016/j.micpath.2020.104123.Epub 2020-03-10.

渤海中央部（中国）におけるHPLC-顔料法とフローサイトメトリーを用いた自己栄養性ピコプランクトン群集の時間的・空間的分布の決定

Determining temporal and spatial distribution of autotrophic picoplankton community composition through HPLC-pigment method and flow cytometry in the central Bohai Sea (China).
  • Guowang Yan
  • Tao Jiang
  • Yaya Zhang
  • Zhengguo Cui
  • Keming Qu
  • Yaoyang Zheng
  • Lin Lu
  • Yu Li
  • Mar. Pollut. Bull..2020 Aug;157:111261. S0025-326X(20)30379-9. doi: 10.1016/j.marpolbul.2020.111261.Epub 2020-06-20.

デリーでのブルセラ症の蔓延につながる水牛飼育員の習慣を特定するための研究である

A study to identify the practices of the buffalo keepers which inadvertently lead to the spread of brucellosis in Delhi.
  • Nimita Kant
  • Parul Kulshreshtha
  • Rashmi Singh
  • Anuradha Mal
  • Amita Dwivedi
  • Riya Ahuja
  • Rinkle Mehra
  • Mohit Tehlan
  • Paritosh Ahmed
  • Shilpa Kaushik
  • Shipra
  • Shashikant Kumar
  • Aas Mohammad
  • Shrikrishn Shukla
  • Damini Singh
  • Rakesh Bhatnagar
  • BMC Vet. Res..2018 Nov;14(1):329. 10.1186/s12917-018-1670-2. doi: 10.1186/s12917-018-1670-2.Epub 2018-11-06.

レーザー末梢眼瞼切開術後の短期眼圧変化の予測因子。A Prospective Randomized Study

Predictors of Short-Term Intraocular Pressure Change after Laser Peripheral Iridotomy: A Prospective Randomized Study.
  • Nazlee Zebardast
  • Srinivasan Kavitha
  • Krishnamurthy Palaniswamy
  • Mohideen Abdul Kader
  • Ganesh Raman
  • Sharmila Rajendrababu
  • Pradeep Y Ramulu
  • Venkatesh Rengaraj
  • Ophthalmol Glaucoma.2018 Nov - Dec;1(3):197-205. S2589-4196(18)30145-5. doi: 10.1016/j.ogla.2018.10.005.Epub 2018-10-19.

早期子宮筋肉腫の補助療法における化学療法の影響。システマティックレビューと更新されたメタアナリシス

Impact of Chemotherapy in the Adjuvant Setting of Early Stage Uterine Leiomyosarcoma: A Systematic Review and Updated Meta-Analysis.
  • Alessandro Rizzo
  • Margherita Nannini
  • Annalisa Astolfi
  • Valentina Indio
  • Pierandrea De Iaco
  • Anna Myriam Perrone
  • Antonio De Leo
  • Lorena Incorvaia
  • Valerio Di Scioscio
  • Maria Abbondanza Pantaleo
  • Cancers (Basel).2020 Jul;12(7). E1899. doi: 10.3390/cancers12071899.Epub 2020-07-14.

左室肥大症における高血圧、血管・心臓リモデリング、高血圧性腎症遺伝子の発現に及ぼすガソトランスミッター処理の影響

Effect of gasotransmitters treatment on expression of hypertension, vascular and cardiac remodeling and hypertensive nephropathy genes in left ventricular hypertrophy.
  • Ashfaq Ahmad
  • Zainab Riaz
  • Munavvar Abdul Sattar
  • Safia Akhtar Khan
  • Edward James John
  • Sumbal Rashid
  • Syed Tahir Abbas Shah
  • Muhammad Arshad Rafiq
  • Maleeha Azam
  • Raheel Qamar
  • Gene.2020 May;737:144479. S0378-1119(20)30148-7. doi: 10.1016/j.gene.2020.144479.Epub 2020-02-14.

ミトコンドリア呼吸は慢性リンパ性白血病の予後マーカーと相関し、イブルチニブ投与により正常化する

Mitochondrial Respiration Correlates with Prognostic Markers in Chronic Lymphocytic Leukemia and Is Normalized by Ibrutinib Treatment.
  • Subir Roy Chowdhury
  • Eric D J Bouchard
  • Ryan Saleh
  • Zoann Nugent
  • Cheryl Peltier
  • Edgard Mejia
  • Sen Hou
  • Carly McFall
  • Mandy Squires
  • Donna Hewitt
  • Linda Davidson
  • Garry X Shen
  • James B Johnston
  • Christine Doucette
  • Grant M Hatch
  • Paul Fernyhough
  • Aaron Marshall
  • Spencer B Gibson
  • David E Dawe
  • Versha Banerji
  • Cancers (Basel).2020 Mar;12(3). E650. doi: 10.3390/cancers12030650.Epub 2020-03-11.

皮質ChATニューロンはアセチルコリンとGABAを標的および脳領域特異的な方法で共同伝達している

Cortical ChAT neurons co-transmit acetylcholine and GABA in a target- and brain-region-specific manner.
  • Adam J Granger
  • Wengang Wang
  • Keiramarie Robertson
  • Mahmoud El-Rifai
  • Andrea F Zanello
  • Karina Bistrong
  • Arpiar Saunders
  • Brian W Chow
  • Vicente Nuñez
  • Miguel Turrero García
  • Corey C Harwell
  • Chenghua Gu
  • Bernardo L Sabatini
  • Elife.2020 Jul;9. e57749. doi: 10.7554/eLife.57749.Epub 2020-07-02.

枯草菌は、真菌細胞の輸送、エネルギー代謝、浸透圧代謝を阻害するイトゥリンAを産生することで、アスペルギルス・カルボナリウスを阻害することが、トランスクリプトーム解析により明らかになりました

Bacillus subtilis inhibits Aspergillus carbonarius by producing iturin A, which disturbs the transport, energy metabolism, and osmotic pressure of fungal cells as revealed by transcriptomics analysis.
  • Chunmei Jiang
  • Zhenzhu Li
  • Yihong Shi
  • Dan Guo
  • Bin Pang
  • Xianqing Chen
  • Dongyan Shao
  • Yanlin Liu
  • Junling Shi
  • Int. J. Food Microbiol..2020 Jul;330:108783. S0168-1605(20)30277-4. doi: 10.1016/j.ijfoodmicro.2020.108783.Epub 2020-07-03.