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日本語AIでPubMedを検索

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日本語AIでPubMedを検索

PubMedの提供する医学論文データベースを日本語で検索できます。AI(Deep Learning)を活用した機械翻訳エンジンにより、精度高く日本語へ翻訳された論文をご参照いただけます。
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みんなが読んでいる論文

先祖代々の遺伝子の再構築と生化学的特徴付けは、イネ科におけるテルペン合成酵素機能の進化についての洞察を与えてくれる

The reconstruction and biochemical characterization of ancestral genes furnish insights into the evolution of terpene synthase function in the Poaceae.
  • Katrin Luck
  • Xinlu Chen
  • Ayla M Norris
  • Feng Chen
  • Jonathan Gershenzon
  • Tobias G Köllner
  • Plant Mol. Biol..2020 Jul;10.1007/s11103-020-01037-4. doi: 10.1007/s11103-020-01037-4.Epub 2020-07-18.

新生児/小児集中治療室における診断ツールとしての全ゲノム迅速シークエンシング

Rapid Whole-Exome Sequencing as a Diagnostic Tool in a Neonatal/Pediatric Intensive Care Unit.
  • Robert Śmigiel
  • Mateusz Biela
  • Krzysztof Szmyd
  • Michal Błoch
  • Elżbieta Szmida
  • Paweł Skiba
  • Anna Walczak
  • Piotr Gasperowicz
  • Joanna Kosińska
  • Małgorzata Rydzanicz
  • Piotr Stawiński
  • Anna Biernacka
  • Marzena Zielińska
  • Waldemar Gołębiowski
  • Agnieszka Jalowska
  • Grażyna Ohia
  • Bożena Głowska
  • Wojciech Walas
  • Barbara Królak-Olejnik
  • Paweł Krajewski
  • Jolanta Sykut-Cegielska
  • Maria M Sąsiadek
  • Rafał Płoski
  • J Clin Med.2020 Jul;9(7). E2220. doi: 10.3390/jcm9072220.Epub 2020-07-13.

C. crescentus xynA2 遺伝子のクローニング、発現および特性評価、および植物バイオマスの分解におけるキシラナーゼIIの応用

Cloning, expression and characterization of C. crescentus xynA2 gene and application of Xylanase II in the deconstruction of plant biomass.
  • Débora Jacomini
  • Larissa Bussler
  • Juliana Moço Corrêa
  • Marina Kimiko Kadowaki
  • Alexandre Maller
  • José Luis da-Conceição Silva
  • Rita de Cássia Garcia Simão
  • Mol. Biol. Rep..2020 Jun;47(6):4427-4438. 10.1007/s11033-020-05507-2. doi: 10.1007/s11033-020-05507-2.Epub 2020-05-18.

アヒルIgY FcとSchisandra chinensis多糖類アジュバントを融合させたRiemerella anatipestifer OmpAの組換えワクチンは、防御免疫応答を向上させる

A recombinant vaccine of Riemerella anatipestifer OmpA fused with duck IgY Fc and Schisandra chinensis polysaccharide adjuvant enhance protective immune response.
  • Shifa Yang
  • Wenwen Dong
  • Guiming Li
  • Zengcheng Zhao
  • Minxun Song
  • Zhongli Huang
  • Jian Fu
  • Fengjuan Jia
  • Shuqian Lin
  • Microb. Pathog..2019 Nov;136:103707. S0882-4010(19)30296-7. doi: 10.1016/j.micpath.2019.103707.Epub 2019-09-03.

カルシトニン遺伝子関連ペプチドおよびアドレノメデュリン受容体へのGタンパク質のカップリングの生化学的特徴付けをネイティブPAGEアッセイを用いて行った

Biochemical characterization of G protein coupling to calcitonin gene-related peptide and adrenomedullin receptors using a native PAGE assay.
  • Amanda M Roehrkasse
  • Margaret L Warner
  • Jason M Booe
  • Augen A Pioszak
  • J. Biol. Chem..2020 Jul;295(28):9736-9751. RA120.013854. doi: 10.1074/jbc.RA120.013854.Epub 2020-06-02.

Corynebacterium glutamicumにおけるキシロースからキシロン酸へのバイオ変換遺伝子の異種発現とバイオプロセスの最適化

Heterologous expression of genes for bioconversion of xylose to xylonic acid in Corynebacterium glutamicum and optimization of the bioprocess.
  • M S Lekshmi Sundar
  • Aliyath Susmitha
  • Devi Rajan
  • Silvin Hannibal
  • Keerthi Sasikumar
  • Volker F Wendisch
  • K Madhavan Nampoothiri
  • AMB Express.2020 Apr;10(1):68. 10.1186/s13568-020-01003-9. doi: 10.1186/s13568-020-01003-9.Epub 2020-04-15.

確率的学習と反転時の注意力測定に及ぼす慢性的な断続的自発的アルコール消費の性依存性効果

Sex-dependent effects of chronic intermittent voluntary alcohol consumption on attentional, not motivational, measures during probabilistic learning and reversal.
  • Claudia G Aguirre
  • Alexandra Stolyarova
  • Kanak Das
  • Saisriya Kolli
  • Vincent Marty
  • Lara Ray
  • Igor Spigelman
  • Alicia Izquierdo
  • PLoS ONE.2020;15(6):e0234729. PONE-D-19-33516. doi: 10.1371/journal.pone.0234729.Epub 2020-06-18.

耳石経路を伴う核前神経障害を伴う先天性第三頭蓋神経麻痺。先天性第三頭蓋神経麻痺の根底には、新しい先天性頭蓋神経障害が存在する

Congenital third cranial nerve palsy with prenuclear dysinnervation involving otolithic pathways: Underpinnings of a novel congenital cranial dysinnervation disorder.
  • Pramod K Pandey
  • Divya Kishore
  • Annu Joon
  • Priya Saraf
  • Indian J Ophthalmol.2020 Jul;68(7):1478-1480. IndianJOphthalmol_2020_68_7_1478_287503. doi: 10.4103/ijo.IJO_1627_19.

食道内視鏡的粘膜下層剥離術後の狭窄予防としてのステロイド注射とポリグリコール酸遮蔽：レトロスペクティブな比較分析

Steroid injection and polyglycolic acid shielding as a prevention against stricture after esophageal endoscopic submucosal dissection: a retrospective comparative analysis.
  • Yoshiki Sakaguchi
  • Yosuke Tsuji
  • Tomohiro Shinozaki
  • Daisuke Ohki
  • Hiroya Mizutani
  • Chihiro Minatsuki
  • Keiko Niimi
  • Nobutake Yamamichi
  • Kazuhiko Koike
  • Gastrointest. Endosc..2020 May;S0016-5107(20)34270-X. doi: 10.1016/j.gie.2020.04.070.Epub 2020-05-03.

運動時の体温上昇は、2型糖尿病ラットの骨格筋におけるAktシグナル伝達経路の活性化に不可欠である

Body temperature elevation during exercise is essential for activating the Akt signaling pathway in the skeletal muscle of type 2 diabetic rats.
  • Takamasa Tsuzuki
  • Toshinori Yoshihara
  • Noriko Ichinoseki-Sekine
  • Ryo Kakigi
  • Yuri Takamine
  • Hiroyuki Kobayashi
  • Hisashi Naito
  • PLoS ONE.2018;13(10):e0205456. PONE-D-18-18834. doi: 10.1371/journal.pone.0205456.Epub 2018-10-10.

NSAID増悪性呼吸器疾患における炎症性マクロファージの記憶

Inflammatory macrophage memory in NSAID-exacerbated respiratory disease.
  • Pascal Haimerl
  • Ulrike Bernhardt
  • Sonja Schindela
  • Fiona Dr Henkel
  • Antonie Lechner
  • Ulrich M Zissler
  • Xavier Pastor
  • Dominique Thomas
  • Alexander Cecil
  • Yan Ge
  • Mark Haid
  • Cornelia Prehn
  • Janina Tokarz
  • Matthias Heinig
  • Jerzy Adamski
  • Carsten B Schmidt-Weber
  • Adam M Chaker
  • Julia Esser-von Bieren
  • J. Allergy Clin. Immunol..2020 Jun;S0091-6749(20)30803-4. doi: 10.1016/j.jaci.2020.04.064.Epub 2020-06-12.

コアシェルポリ(D,l-ラクチド-コ-グリコリド)-キトサンナノスフェアとシムバスタチン-ドキシサイクリンを用いた歯周および骨修復のためのコアシェルキトサンナノスフェア

Core-Shell poly-(D,l-Lactide-co-Glycolide)-chitosan Nanospheres with simvastatin-doxycycline for periodontal and osseous repair.
  • Po-Chun Chang
  • Wei-Chiu Tai
  • Hui-Ting Luo
  • Chern-Hsiung Lai
  • Hsu-Hsiang Lin
  • Zhi-Jie Lin
  • Ying-Chieh Chang
  • Bor-Shiunn Lee
  • Int. J. Biol. Macromol..2020 May;158:627-635. S0141-8130(20)33043-9. doi: 10.1016/j.ijbiomac.2020.04.183.Epub 2020-05-07.

Ad5 ベクター化 HIV ワクチン接種者における粘膜 T 細胞の長期的な活性化とホーミング表現型

Long-term mucosal T cell activation and homing phenotypes in recipients of an Ad5-vectored HIV vaccine.
  • Marcel E Curlin
  • Jason Shao
  • Gabriela Diaz
  • Paul T Edlefsen
  • Richard M Novak
  • Kenneth H Mayer
  • Mary Allen
  • Cecilia Morgan
  • Janine Maenza
  • Susan Buchbinder
  • Michael C Keefer
  • Stephen C De Rosa
  • Lawrence Corey
  • Ann Duerr
  • Vaccine.2020 Jul;S0264-410X(20)30829-X. doi: 10.1016/j.vaccine.2020.06.043.Epub 2020-07-14.

ネオアジュバント化学療法後の乳癌における腋窩ステージングの問題点。標的腋窩郭清の役割とリンパ節マーカーの種類

The problem of axillary staging in breast cancer after neoadjuvant chemotherapy. Role of targeted axillary dissection and types of lymph node markers.
  • Diego Flores-Funes
  • José Aguilar-Jiménez
  • María Martínez-Gálvez
  • María José Ibáñez-Ibáñez
  • Luis Carrasco-González
  • José Ignacio Gil-Izquierdo
  • José Luis Aguayo-Albasini
  • Cir Esp.2020 May;S0009-739X(20)30097-X. doi: 10.1016/j.ciresp.2020.03.012.Epub 2020-05-05.

電気熱原子吸光分析法を用いた液相マイクロ抽出をベースとした環境に優しい超音波支援型深層共晶溶媒による水中および生物学的試料中の水銀のスペシエーション

Speciation of mercury in water and biological samples by eco-friendly ultrasound-assisted deep eutectic solvent based on liquid phase microextraction with electrothermal atomic absorption spectrometry.
  • Arnon Thongsaw
  • Yuthapong Udnan
  • Gareth M Ross
  • Wipharat Chuachuad Chaiyasith
  • Talanta.2019 May;197:310-318. S0039-9140(19)30018-9. doi: 10.1016/j.talanta.2019.01.018.Epub 2019-01-09.

三酸化ヒ素はインターフェロン阻害を介して形質細胞性樹状細胞の調節機能を誘導する

Arsenic trioxide induces regulatory functions of plasmacytoid dendritic cells through interferon- inhibition.
  • Yishan Ye
  • Laure Ricard
  • Lama Siblany
  • Nicolas Stocker
  • Frédéric De Vassoigne
  • Eolia Brissot
  • Baptiste Lamarthée
  • Arsène Mekinian
  • Mohamad Mohty
  • Béatrice Gaugler
  • Florent Malard
  • Acta Pharm Sin B.2020 Jun;10(6):1061-1072. S2211-3835(19)30954-2. doi: 10.1016/j.apsb.2020.01.016.Epub 2020-01-31.

HNF1A糖尿病（3型若年者の成熟期糖尿病）患者におけるリナグリプチン治療の有無にかかわらずグリメピリドの有効性と安全性。A Randomized, Double-Blinded, Placebo-Controlled, Crossover Trial (GLIMLINA)

Efficacy and Safety of Glimepiride With or Without Linagliptin Treatment in Patients With HNF1A Diabetes (Maturity-Onset Diabetes of the Young Type 3): A Randomized, Double-Blinded, Placebo-Controlled, Crossover Trial (GLIMLINA).
  • Alexander S Christensen
  • Sofie Hædersdal
  • Julie Støy
  • Heidi Storgaard
  • Ulla Kampmann
  • Julie L Forman
  • Marta Seghieri
  • Jens J Holst
  • Torben Hansen
  • Filip K Knop
  • Tina Vilsbøll
  • Diabetes Care.2020 Jul;dc200408. doi: 10.2337/dc20-0408.Epub 2020-07-13.

メンサピペリタ精油への連続暴露は、持続的に流行するサルモネラ菌PT4の培養性に影響を与え、膜修復を誘導することがわかった

Successive exposure to Mentha piperita L. essential oil affects the culturability and induces membrane repair in a persister epidemic Salmonella Typhimurium PT4.
  • Adma Nadja Ferreira de Melo
  • Geany Targino de Souza Pedrosa
  • Erika Tayse da Cruz Almeida
  • Guojie Cao
  • Dumitru Macarisin
  • Donald W Schaffner
  • Evandro L de Souza
  • Marciane Magnani
  • Microb. Pathog..2020 May;149:104264. S0882-4010(20)30630-6. doi: 10.1016/j.micpath.2020.104264.Epub 2020-05-25.

花粉がインフルエンザ様の流行を抑制する季節的要因と思われる花粉の数と花粉症とインフルエンザ様発症率の逆関係を調べたオランダの研究 2016-2019年

Pollen likely seasonal factor in inhibiting flu-like epidemics. A Dutch study into the inverse relation between pollen counts, hay fever and flu-like incidence 2016-2019.
  • Martijn J Hoogeveen
  • Sci. Total Environ..2020 Jul;727:138543. S0048-9697(20)32056-8. doi: 10.1016/j.scitotenv.2020.138543.Epub 2020-04-17.

モリンガオレイフェラ茎（MOS）加工飼料を給与した場合の産卵鴨の成長・産卵成績および免疫・抗酸化活性に及ぼす影響

Effects of feeding diets with processed Moringa oleifera stem meal on growth and laying performance, and immunological and antioxidant activities in laying ducks.
  • S L Yang
  • R C Yang
  • X Zhou
  • S H Yang
  • L L Luo
  • Y C Zhu
  • Surintorn Boonanuntan
  • Poult. Sci..2020 Jul;99(7):3445-3451. S0032-5791(20)30238-8. doi: 10.1016/j.psj.2020.04.002.Epub 2020-04-24.

CFTR補正装置ABBV-2222/GLPG2222によるF508delCFTRタンパク質プロセシングの生物学的特性評価

Biological Characterization of F508delCFTR Protein Processing by the CFTR Corrector ABBV-2222/GLPG2222.
  • Ashvani K Singh
  • Yihong Fan
  • Corina Balut
  • Sara Alani
  • Arlene M Manelli
  • Andrew M Swensen
  • Ying Jia
  • Torben R Neelands
  • Timothy A Vortherms
  • Bo Liu
  • Xenia B Searle
  • Xueqing Wang
  • Wenqing Gao
  • Tzyh-Chang Hwang
  • Hong Y Ren
  • Douglas Cyr
  • Philip R Kym
  • Katja Conrath
  • Chris Tse
  • J. Pharmacol. Exp. Ther..2020 01;372(1):107-118. jpet.119.261800. doi: 10.1124/jpet.119.261800.Epub 2019-11-15.

妊娠中の食事因子と小児期のアトピーの転帰：アレルギーと臨床免疫学の欧州アカデミーからの系統的レビュー

Dietary factors during pregnancy and atopic outcomes in childhood: a systematic review from the European Academy of Allergy and Clinical Immunology.
  • C Venter
  • C Agostoni
  • S H Arshad
  • M Ben-Abdallah
  • G Du Toit
  • D M Fleischer
  • M Greenhawt
  • D H Glueck
  • M Groetch
  • N Lunjani
  • K Maslin
  • A Maiorella
  • R Meyer
  • A Muraro
  • M J Netting
  • B I Nwaru
  • D J Palmer
  • M P Palumbo
  • G Roberts
  • C Roduit
  • P K Smith
  • E Untersmayr
  • L Vanderlinden
  • L O'Mahony
  • Pediatr Allergy Immunol.2020 Jun;doi: 10.1111/pai.13303.Epub 2020-06-10.

漢方薬Radix Paeoniae Rubraがアラキドン酸経路のPTGS2を調節して慢性骨盤内炎症疾患を改善するメカニズムの研究

Research on the mechanism of Chinese herbal medicine Radix Paeoniae Rubra in improving chronic pelvic inflammation disease by regulating PTGS2 in the arachidonic acid pathway.
  • Xiao-Hong Li
  • Yan-Ru Liu
  • Da-Hai Jiang
  • Zhi-Shu Tang
  • Da-Wei Qian
  • Zhong-Xing Song
  • Lin Chen
  • Xin-Bo Shi
  • Ning-Juan Yang
  • Ya-Feng Yan
  • Ai-Bing Chang
  • Biomed. Pharmacother..2020 Jun;129:110052. S0753-3322(20)30243-2. doi: 10.1016/j.biopha.2020.110052.Epub 2020-06-16.

心房間ブロック、左房線維症、機械的同期不全との関連性：心電図と磁気共鳴画像の相関

Association between interatrial block, left atrial fibrosis, and mechanical dyssynchrony: Electrocardiography-magnetic resonance imaging correlation.
  • Luisa Ciuffo
  • Vanesa Bruña
  • Manuel Martínez-Sellés
  • Henrique Doria de Vasconcellos
  • Susumu Tao
  • Tarek Zghaib
  • Saman Nazarian
  • David D Spragg
  • Joseph Marine
  • Ronald D Berger
  • Joao A C Lima
  • Hugh Calkins
  • Antonio Bayés-de-Luna
  • Hiroshi Ashikaga
  • J. Cardiovasc. Electrophysiol..2020 Jul;31(7):1719-1725. doi: 10.1111/jce.14608.Epub 2020-06-15.

悪性胸膜中皮腫におけるBAP-1免疫組織化学の予後的役割を問う。システマティックレビューとメタアナリシスを用いた単一施設の経験

Questioning the prognostic role of BAP-1 immunohistochemistry in malignant pleural mesothelioma: A single center experience with systematic review and meta-analysis.
  • Luca Cantini
  • Federica Pecci
  • Alberto Murrone
  • Marco Tomasetti
  • Cecilia Copparoni
  • Ilaria Fiordoliva
  • Francesca Morgese
  • Silvia Rinaldi
  • Paola Mazzanti
  • Corrado Rubini
  • Alessia Cimadamore
  • Francesca Barbisan
  • Riccardo Giampieri
  • Marina Scarpelli
  • Lory Santarelli
  • Rossana Berardi
  • Lung Cancer.2020 Aug;146:318-326. S0169-5002(20)30498-0. doi: 10.1016/j.lungcan.2020.06.024.Epub 2020-06-21.