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日本語AIでPubMedを検索

日本語AIでPubMedを検索

PubMedの提供する医学論文データベースを日本語で検索できます。AI(Deep Learning)を活用した機械翻訳エンジンにより、精度高く日本語へ翻訳された論文をご参照いただけます。

みんなが読んでいる論文

伸長因子-Tuは、tRNA選択のプルーフリーディング段階において、リボソーム内のアミノアシル-tRNAを繰り返し係合させることができる

Elongation factor-Tu can repetitively engage aminoacyl-tRNA within the ribosome during the proofreading stage of tRNA selection.
  • Justin C Morse
  • Dylan Girodat
  • Benjamin J Burnett
  • Mikael Holm
  • Roger B Altman
  • Karissa Y Sanbonmatsu
  • Hans-Joachim Wieden
  • Scott C Blanchard
  • Proc. Natl. Acad. Sci. U.S.A..2020 02;117(7):3610-3620. 1904469117. doi: 10.1073/pnas.1904469117.Epub 2020-02-05.

A Triad of Ketoacidosis, hypertriglyceridemia, and Acute Pancreatitis Associated With Sugar-Sweetened Soft Drinks Abuse in a Caucasian Patient With Uniagnosed Type 2 Diabetes Mellitus

A Triad of Ketoacidosis, Hypertriglyceridemia, and Acute Pancreatitis Associated With Sugar-Sweetened Soft Drinks Abuse in a Caucasian Patient With Undiagnosed Type 2 Diabetes Mellitus.
  • Alessandra Vitelli
  • Valentina Apuzzi
  • Francesco Calderaro
  • Olimpia Fattoruso
  • Vincenzo Bassi
  • Cureus.2020 May;12(5):e8299. doi: 10.7759/cureus.8299.Epub 2020-05-26.

バイオ炭とウレアーゼ・硝化抑制剤の複合施用は、水田におけるCH排出量削減に相乗効果を発揮する。3 年間の研究

Combined application of biochar with urease and nitrification inhibitors have synergistic effects on mitigating CH emissions in rice field: A three-year study.
  • Tiehu He
  • Junji Yuan
  • Jiafa Luo
  • Stuart Lindsey
  • Jian Xiang
  • Yongxin Lin
  • Deyan Liu
  • Zengming Chen
  • Weixin Ding
  • Sci. Total Environ..2020 Jul;743:140500. S0048-9697(20)34022-5. doi: 10.1016/j.scitotenv.2020.140500.Epub 2020-07-03.

南アフリカ、ムプマランガ州の急性発熱患者における細菌性人獣共通感染症の危険因子

Risk factors for bacterial zoonotic pathogens in acutely febrile patients in Mpumalanga Province, South Africa.
  • Amanda M Berrian
  • Beatriz Martínez-López
  • Vanessa Quan
  • Patricia A Conrad
  • Jacques van Rooyen
  • Gregory J G Simpson
  • John Frean
  • Jacqueline Weyer
  • Jennifer Rossouw
  • Darryn Knobel
  • Lucille Blumberg
  • Zoonoses Public Health.2019 08;66(5):458-469. doi: 10.1111/zph.12577.Epub 2019-03-11.

TP53突然変異のランドスケープを計算科学的に解析すると、頭頸部扁平上皮癌における予後の鍵となるシグネチャーと明確な経路が明らかになる

Computational analysis of TP53 mutational landscape unveils key prognostic signatures and distinct pathobiological pathways in head and neck squamous cell cancer.
  • Vito Carlo Alberto Caponio
  • Giuseppe Troiano
  • Iolanda Adipietro
  • Khrystyna Zhurakivska
  • Claudia Arena
  • Domenica Mangieri
  • Marco Mascitti
  • Nicola Cirillo
  • Lorenzo Lo Muzio
  • Br. J. Cancer.2020 Jul;10.1038/s41416-020-0984-6. doi: 10.1038/s41416-020-0984-6.Epub 2020-07-20.

樹脂抽出物の抗炎症性組成物は、ラットのモノヨードアセテート誘発性変形性関節炎における疼痛を緩和し、軟骨を保護する

An Anti-Inflammatory Composition of Resin Extracts Alleviates Pain and Protects Cartilage in Monoiodoacetate-Induced Osteoarthritis in Rats.
  • Venkata Krishnaraju Alluri
  • Sreenath Kundimi
  • Krishanu Sengupta
  • Trimurtulu Golakoti
  • Eswar Kumar Kilari
  • Evid Based Complement Alternat Med.2020;2020:7381625. doi: 10.1155/2020/7381625.Epub 2020-05-21.

経皮的冠動脈インターベンション成功後の急性心筋梗塞患者および糖尿病予備軍患者における、耐久性のあるポリマーと生分解性ポリマーをベースとした新世代の薬剤溶出ステントの比較

Comparison of Durable-Polymer- and Biodegradable-Polymer-Based Newer-Generation Drug-Eluting Stents in Patients with Acute Myocardial Infarction and Prediabetes After Successful Percutaneous Coronary Intervention.
  • Yong Hoon Kim
  • Ae-Young Her
  • Myung Ho Jeong
  • Byeong-Keuk Kim
  • Sung-Jin Hong
  • Seunghwan Kim
  • Chul-Min Ahn
  • Jung-Sun Kim
  • Young-Guk Ko
  • Donghoon Choi
  • Myeong-Ki Hong
  • Yangsoo Jang
  • Int Heart J.2020 Jul;doi: 10.1536/ihj.19-654.Epub 2020-07-18.

ラット後根神経節ニューロンにおけるKv7.2のRNA干渉を介したサイレンシングは、選択的チャネルオープナーの抗侵害受容作用を消失させることがわかった

RNA interference-mediated silencing of Kv7.2 in rat dorsal root ganglion neurons abolishes the anti-nociceptive effect of a selective channel opener.
  • Markus Valdor
  • Anke Wagner
  • Heike Fischer
  • Viola Röhrs
  • Wolfgang Schröder
  • Gregor Bahrenberg
  • André Welbers
  • Henry Fechner
  • Jens Kurreck
  • Thomas M Tzschentke
  • Thomas Christoph
  • J Pharmacol Toxicol Methods.2020 May - Jun;103:106693. S1056-8719(20)30022-8. doi: 10.1016/j.vascn.2020.106693.Epub 2020-04-08.

ペクチン修飾FeO NP上にPd NPを作製した。磁性ナノ触媒を用いたC-CおよびC-Nクロスカップリング反応と心血管保護効果の検討

Fabrication of Pd NPs on pectin-modified FeO NPs: A magnetically nanocatalyst for C-C and C-N cross coupling reactions and investigating the cardiovascular protective effects.
  • Wei Zhang
  • Hojat Veisi
  • Reyhaneh Sharifi
  • Delafarin Salamat
  • Bikash Karmakar
  • Malak Hekmati
  • Saba Hemmati
  • Zhiyong Zhang
  • Qiang Su
  • Mohammad Mahdi Zangeneh
  • Int. J. Biol. Macromol..2020 May;S0141-8130(20)33416-4. doi: 10.1016/j.ijbiomac.2020.05.247.Epub 2020-05-30.

多嚢胞性卵巣症候群-痰湿潤症候群のインスリン抵抗性を持つ不妊患者の卵巣顆粒膜細胞におけるIRS-1/PI3K/GLUT4経路の発現に対する電気鍼治療の効果

Effect of Electro-acupuncture on Expression of IRS-1/PI3K/GLUT4 Pathway in Ovarian Granulosa Cells of Infertile Patients with Polycystic Ovary Syndrome-Insulin Resistance of Phlegm-Dampness Syndrome.
  • Shan Xiang
  • Ming-Feng Xia
  • Jing-Yan Song
  • Dan-Qi Liu
  • Fang Lian
  • Chin J Integr Med.2020 Jun;10.1007/s11655-020-3219-z. doi: 10.1007/s11655-020-3219-z.Epub 2020-06-22.

血管周囲幹細胞由来シクロフィリンAはHIF1α依存性血管新生を介してアッシャーマン症候群の子宮環境を改善する

Perivascular Stem Cell-Derived Cyclophilin A Improves Uterine Environment with Asherman's Syndrome via HIF1α-Dependent Angiogenesis.
  • Mira Park
  • Seok-Ho Hong
  • So Hee Park
  • Yeon Sun Kim
  • Seung Chel Yang
  • Hye-Ryun Kim
  • Songmi Noh
  • Sunghun Na
  • Hyung Keun Lee
  • Hyunjung J Lim
  • Sang Woo Lyu
  • Haengseok Song
  • Mol. Ther..2020 May;S1525-0016(20)30249-5. doi: 10.1016/j.ymthe.2020.05.015.Epub 2020-05-20.

新生児集中治療室における抗菌薬の投与。臨床実践は薬物動態学に基づく推奨事項を反映しているか?

Dosing of Antimicrobials in the Neonatal Intensive Care Unit: Does Clinical Practice Reflect Pharmacokinetics-based Recommendations?
  • Ashley Stark
  • Julie Childers
  • Morgan England
  • Reese H Clark
  • Matthew Laughon
  • Michael Cohen-Wolkowiez
  • Daniel K Benjamin
  • P Brian Smith
  • Kelly Wade
  • Rachel G Greenberg
  • Pediatr. Infect. Dis. J..2020 Aug;39(8):713-717. 00006454-202008000-00014. doi: 10.1097/INF.0000000000002657.

FMRPを欠損したヒト多能性幹細胞由来の皮質神経細胞は、自然発火パターンの変化を示す

Cortical neurons derived from human pluripotent stem cells lacking FMRP display altered spontaneous firing patterns.
  • Shreya Das Sharma
  • Rakhi Pal
  • Bharath Kumar Reddy
  • Bhuvaneish T Selvaraj
  • Nisha Raj
  • Krishna Kumar Samaga
  • Durga J Srinivasan
  • Loren Ornelas
  • Dhruv Sareen
  • Matthew R Livesey
  • Gary J Bassell
  • Clive N Svendsen
  • Peter C Kind
  • Siddharthan Chandran
  • Sumantra Chattarji
  • David J A Wyllie
  • Mol Autism.2020 Jun;11(1):52. 10.1186/s13229-020-00351-4. doi: 10.1186/s13229-020-00351-4.Epub 2020-06-19.

慢性ストレスと咬合不安定性によって誘発される咀嚼筋機能障害に対するベンゾジアゼピンの有益な効果を動物実験で明らかにした

Beneficial effects of benzodiazepine on masticatory muscle dysfunction induced by chronic stress and occlusal instability in an experimental animal study.
  • Glauce C Nascimento
  • Bruno L Malzone
  • Daniela M Iyomasa
  • Yamba C L Pereira
  • João Paulo M Issa
  • Christie R A Leite-Panissi
  • Ii-Sei Watanabe
  • Mamie M Iyomasa
  • Ramon Fuentes
  • Elaine Del Bel
  • Fernando J Dias
  • Sci Rep.2020 May;10(1):8787. 10.1038/s41598-020-65524-w. doi: 10.1038/s41598-020-65524-w.Epub 2020-05-29.

臨床血圧測定のオブザーバーのパフォーマンスの最適化: Lancet Commission on Hypertension Groupからのポジションステートメント動脈圧測定におけるオブザーバーのパフォーマンスの最適化: Posicionamento do Grupo da

[Optimizing observer performance of clinic blood Pressure measurement: a position statement from the Lancet Commission on Hypertension GroupOtimização do desempenho do observador na medição clínica da pressão arterial: posicionamento do Grupo da ].
  • Raj Padwal
  • Norm R C Campbell
  • Aletta E Schutte
  • Michael Hecht Olsen
  • Christian Delles
  • Anthony Etyang
  • J Kennedy Cruickshank
  • George Stergiou
  • Michael K Rakotz
  • Gregory Wozniak
  • Marc G Jaffe
  • Ivor Benjamin
  • Gianfranco Parati
  • James E Sharman
  • Rev. Panam. Salud Publica.2020;44:e88. RPSP.2020.88. doi: 10.26633/RPSP.2020.88.Epub 2020-07-15.

網膜眼底写真における糖尿病性網膜症の検出のためのディープラーニングアルゴリズム。システマティックレビューとメタアナリシス

Deep learning algorithms for detection of diabetic retinopathy in retinal fundus photographs: A systematic review and meta-analysis.
  • Md Mohaimenul Islam
  • Hsuan-Chia Yang
  • Tahmina Nasrin Poly
  • Wen-Shan Jian
  • Yu-Chuan Jack Li
  • Comput Methods Programs Biomed.2020 Jul;191:105320. S0169-2607(19)31101-0. doi: 10.1016/j.cmpb.2020.105320.Epub 2020-01-16.

前立腺肥大症に対するホルミウムレーザーによる前立腺の核出術と経尿道的前立腺切除術との間の前立腺癌の診断価値:レトロスペクティブな比較研究

The diagnostic value of prostate cancer between holmium laser enucleation of the prostate and transurethral resection of the prostate for benign prostatic hyperplasia: A retrospective comparative study.
  • Gaofei He
  • Chengfang Sun
  • Yuanyuan Shu
  • Bohan Wang
  • Chuanjun Du
  • Jimin Chen
  • Jiaming Wen
  • Int J Surg.2020 Jul;79:217-221. S1743-9191(20)30408-8. doi: 10.1016/j.ijsu.2020.05.025.Epub 2020-05-21.

RGS4はPGE2生合成を阻害することで、アレルゲンやアスピリンに関連した気道過敏反応性を促進する

RGS4 promotes allergen- and aspirin-associated airway hyperresponsiveness by inhibiting PGE2 biosynthesis.
  • Gordon S Wong
  • Jamie L Redes
  • Nariman Balenga
  • Morgan McCullough
  • Nathalie Fuentes
  • Ameya Gokhale
  • Cynthia Koziol-White
  • Joseph A Jude
  • Laura A Madigan
  • Eunice C Chan
  • William H Jester
  • Sabrina Biardel
  • Nicolas Flamand
  • Reynold A Panettieri
  • Kirk M Druey
  • J. Allergy Clin. Immunol..2020 Mar;S0091-6749(20)30372-9. doi: 10.1016/j.jaci.2020.03.004.Epub 2020-03-19.

組換えアディポネクチンペプチドは、Smad3 シグナル阻害を介して糖尿病マウスのミトコンドリアおよび ATF4-CHOP アポトーシス経路を抑制し、脳内出血後の神経細胞の生存を促進する

Recombinant adiponectin peptide promotes neuronal survival after intracerebral haemorrhage by suppressing mitochondrial and ATF4-CHOP apoptosis pathways in diabetic mice via Smad3 signalling inhibition.
  • Xun Wu
  • Jianing Luo
  • Haixiao Liu
  • Wenxing Cui
  • Wei Guo
  • Lei Zhao
  • Hao Guo
  • Hao Bai
  • Kang Guo
  • Dayun Feng
  • Yan Qu
  • Cell Prolif..2020 Feb;53(2):e12759. doi: 10.1111/cpr.12759.Epub 2020-01-10.

プレグナンX受容体-シトクロムP450s軸の活性化:PEG化リポソームの強化された血液クリアランス促進現象の可能な理由

Activation of Pregnane X Receptor-Cytochrome P450s Axis: A Possible Reason for the Enhanced Accelerated Blood Clearance Phenomenon of PEGylated Liposomes In Vivo.
  • Fengling Wang
  • Huihui Wang
  • Yifan Wu
  • Lei Wang
  • Ling Zhang
  • Xi Ye
  • Daiyin Peng
  • Weidong Chen
  • Drug Metab. Dispos..2019 08;47(8):785-793. dmd.119.086769. doi: 10.1124/dmd.119.086769.Epub 2019-05-22.

切除不能な肝細胞がんに対する肝動脈化学塞栓療法とスニチニブ。PRODIGE 16試験の結果

Liver transarterial chemoembolization and sunitinib for unresectable hepatocellular carcinoma: Results of the PRODIGE 16 study.
  • Anthony Turpin
  • Thierry de Baere
  • Alexandra Heurgué
  • Karine Le Malicot
  • Isabelle Ollivier-Hourmand
  • Thierry Lecomte
  • Hervé Perrier
  • Julien Vergniol
  • David Sefrioui
  • Yves Rinaldi
  • Julien Edeline
  • Jean-Louis Jouve
  • Christine Silvain
  • Yves Becouarn
  • Barbara Dauvois
  • Mathieu Baconnier
  • Maryline Debette-Gratien
  • Gael Deplanque
  • Sébastien Dharancy
  • Côme Lepage
  • Mohamed Hebbar
  • Clin Res Hepatol Gastroenterol.2020 Jun;S2210-7401(20)30157-1. doi: 10.1016/j.clinre.2020.05.012.Epub 2020-06-21.

アルゼンチンにおける事故、自殺、殺人による死亡率の傾向の再計算(1997-2018年)事故、自殺、殺人による死亡率の傾向の再計算(1997-2018年)アルゼンチンにおける事故、自殺、殺人による死亡率の傾向の再計算

[Recalculation of trends in mortality from accidents, suicides, and homicides in Argentina, 1997-2018Recálculo das tendências de mortalidade por acidentes, suicídios e homicídios na Argentina, 1997-2018].
  • Adrián Santoro
  • Rev. Panam. Salud Publica.2020;44:e74. RPSP.2020.74. doi: 10.26633/RPSP.2020.74.Epub 2020-07-15.

浸透性角膜形成術におけるエキシマレーザーとフェムト秒レーザーアシストトレフィネーションの比較。レトロスペクティブ研究

Comparison of Excimer Laser Versus Femtosecond Laser Assisted Trephination in Penetrating Keratoplasty: A Retrospective Study.
  • Gábor Tóth
  • Nóra Szentmáry
  • Achim Langenbucher
  • Elina Akhmedova
  • Moatasem El-Husseiny
  • Berthold Seitz
  • Adv Ther.2019 12;36(12):3471-3482. 10.1007/s12325-019-01120-3. doi: 10.1007/s12325-019-01120-3.Epub 2019-10-24.

ベースラインのKarnofskyパフォーマンスステータスは、転移性疾患に対する頭蓋内放射線治療終了後30日以内の死亡を独立して予測する

Baseline Karnofsky performance status is independently predictive of death within 30 days of intracranial radiation therapy completion for metastatic disease.
  • Shearwood McClelland Iii
  • Namita Agrawal
  • May F Elbanna
  • Kevin Shiue
  • Gregory K Bartlett
  • Tim Lautenschlaeger
  • Richard C Zellars
  • Gordon A Watson
  • Susannah G Ellsworth
  • Rep Pract Oncol Radiother.2020 Jul-Aug;25(4):698-700. S1507-1367(20)30028-6. doi: 10.1016/j.rpor.2020.02.014.Epub 2020-02-24.

薬剤溶出ステントまたは薬剤溶出バルーン治療後の薬剤溶出型とベアメタル型のステント内再狭窄の臨床成績。システマティックレビューとメタアナリシス

Clinical Outcomes of Drug-Eluting versus Bare-Metal In-Stent Restenosis after the Treatment of Drug-Eluting Stent or Drug-Eluting Balloon: A Systematic Review and Meta-Analysis.
  • Yi-Xing Yang
  • Yin Liu
  • Chang-Ping Li
  • Peng-Ju Lu
  • Jiao Wang
  • Jing Gao
  • J Interv Cardiol.2020;2020:8179849. doi: 10.1155/2020/8179849.Epub 2020-06-26.

大細胞肺神経内分泌がんにおけるPD-L1発現パターン:これらの患者における免疫療法の使用の潜在的な意味合い:GFPC 03-2017「EPNEC」試験

PD-L1-expression patterns in large-cell neuroendocrine carcinoma of the lung: potential implications for use of immunotherapy in these patients: the GFPC 03-2017 "EPNEC" study.
  • Dominique Arpin
  • Marie-Christine Charpentier
  • Marie Bernardi
  • Isabelle Monnet
  • Aurelie Boni
  • Emmanuel Watkin
  • Isabelle Goubin-Versini
  • Régine Lamy
  • Laurence Gérinière
  • Margaux Geier
  • Fabien Forest
  • Radj Gervais
  • Anne Madrosyk
  • Florian Guisier
  • Cécile Serrand
  • Chrystèle Locher
  • Chantal Decroisette
  • Pierre Fournel
  • Jean-Bernard Auliac
  • Thierry Jeanfaivre
  • Jacques Letreut
  • Hélène Doubre
  • Geraldine Francois
  • Nicolas Piton
  • Christos Chouaïd
  • Diane Damotte
  • Ther Adv Med Oncol.2020;12:1758835920937972. 10.1177_1758835920937972. doi: 10.1177/1758835920937972.Epub 2020-07-07.

胃切除術を受けた高齢の胃がん患者における非在宅退院の予測には、修正されたFrailty Indexが有用である

Modified Frailty Index is Useful in Predicting Non-home Discharge in Elderly Patients with Gastric Cancer Who Undergo Gastrectomy.
  • Tomohiro Osaki
  • Hiroaki Saito
  • Shota Shimizu
  • Yuki Murakami
  • Kozo Miyatani
  • Tomoyuki Matsunaga
  • Shigeru Tatebe
  • Masahide Ikeguchi
  • Yoshiyuki Fujiwara
  • World J Surg.2020 Jul;10.1007/s00268-020-05691-z. doi: 10.1007/s00268-020-05691-z.Epub 2020-07-13.

前進浸透膜の防汚性を向上させるために、銀をコアにした金属有機フレームワーク(Ag-MOF)の機能化を行い、銀をコアにした金属有機フレームワーク(Ag-MOF)をその場で成長させることを試みた

In-Situ Ag-MOFs Growth on Pre-Grafted Zwitterions Imparts Outstanding Antifouling Properties to Forward Osmosis Membranes.
  • Mehdi Pejman
  • Mostafa Dadashi Firouzjaei
  • Sadegh Aghapour Aktij
  • Parnab Das
  • Ehsan Zolghadr
  • Hesam Jafarian
  • Ahmad Arabi Shamsabadi
  • Mark A Elliott
  • Mohtada Sadrzadeh
  • Marco Sangermano
  • Ahmad Rahimpour
  • Alberto Tiraferri
  • ACS Appl Mater Interfaces.2020 Jul;doi: 10.1021/acsami.0c12141.Epub 2020-07-17.

630人の患者を対象とした好酸球性食道炎に対するプロトンポンプ阻害薬治療の有効性:EoE connect registryの結果

Efficacy of proton pump inhibitor therapy for eosinophilic oesophagitis in 630 patients: results from the EoE connect registry.
  • Emilio J Laserna-Mendieta
  • Sergio Casabona
  • Danila Guagnozzi
  • Edoardo Savarino
  • Antonia Perelló
  • Antonio Guardiola-Arévalo
  • Jesús Barrio
  • Isabel Pérez-Martínez
  • Anne Lund Krarup
  • Javier Alcedo
  • Susana de la Riva
  • Esther Rey-Iborra
  • Cecilio Santander
  • Ángel Arias
  • Alfredo J Lucendo
  • Aliment. Pharmacol. Ther..2020 Jul;doi: 10.1111/apt.15957.Epub 2020-07-17.

マクロテクスチャーの乳房インプラントおよび乳房の未分化大細胞リンパ腫を有する女性におけるBRCA1/2変異の有病率の増加

Increased prevalence of BRCA1/2 mutations in women with macro-textured breast implants and anaplastic large cell lymphoma of the breast.
  • Mintsje De Boer
  • Michael Hauptmann
  • Nathalie J Hijmering
  • Carel J M van Noesel
  • Hinne A Rakhorst
  • Hanne Ej Meijers-Heijboer
  • Jan Paul De Boer
  • René Rwj van der Hulst
  • Daphne De Jong
  • Flora E van Leeuwen
  • Blood.2020 May;blood.2019004498. doi: 10.1182/blood.2019004498.Epub 2020-05-26.

C9orf72は腸内細菌によって誘導される全身および神経の炎症を抑制します

C9orf72 suppresses systemic and neural inflammation induced by gut bacteria.
  • Aaron Burberry
  • Michael F Wells
  • Francesco Limone
  • Alexander Couto
  • Kevin S Smith
  • James Keaney
  • Gaëlle Gillet
  • Nick van Gastel
  • Jin-Yuan Wang
  • Olli Pietilainen
  • Menglu Qian
  • Pierce Eggan
  • Christopher Cantrell
  • Joanie Mok
  • Irena Kadiu
  • David T Scadden
  • Kevin Eggan
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レシピエント精巣における生殖細胞枯渇は、レチノイン酸不足を介して、整形外科的に移植された精巣片の造精子形成に悪影響を及ぼす

Germ cell depletion in recipient testis has adverse effects on spermatogenesis in orthotopically transplanted testis pieces via retinoic acid insufficiency.
  • Akihiro Tsuchimoto
  • Masaaki Tone
  • Narumi Ogonuki
  • Masashi Hada
  • Atsuo Ogura
  • Seiji Takashima
  • Sci Rep.2020 Jul;10(1):10796. 10.1038/s41598-020-67595-1. doi: 10.1038/s41598-020-67595-1.Epub 2020-07-01.

ForenSeq™ DNA Signature Prep Kitとレーザーで微小解剖した細胞との互換性。細胞数の少ないサンプルで発生する問題点を探る

Compatibility of the ForenSeq™ DNA Signature Prep Kit with laser microdissected cells: An exploration of issues that arise with samples containing low cell numbers.
  • Ryan England
  • Gemma Nancollis
  • Janet Stacey
  • Andrew Sarman
  • Jason Min
  • SallyAnn Harbison
  • Forensic Sci Int Genet.2020 Jul;47:102278. S1872-4973(20)30051-X. doi: 10.1016/j.fsigen.2020.102278.Epub 2020-05-01.

上腕骨近位部骨折に対するステムドヘミア関節形成術と比較した逆全肩関節形成術:5946人の患者のレジストリ分析

Reverse total shoulder arthroplasty compared to stemmed hemiarthroplasty for proximal humeral fractures: a registry analysis of 5946 patients.
  • Owain Critchley
  • Andrew McLean
  • Richard Page
  • Fraser Taylor
  • Stephen Graves
  • Michelle Lorimer
  • Yi Peng
  • Alesha Hatton
  • Gregory Bain
  • J Shoulder Elbow Surg.2020 Jun;S1058-2746(20)30306-2. doi: 10.1016/j.jse.2020.04.005.Epub 2020-06-09.

母性ベタインサプリメントは、SREBP2とCYP7A1遺伝子のエピジェネティックな変調を持つ鶏の子孫における肝コレステロール沈着を減少させます

Maternal betaine supplementation decreases hepatic cholesterol deposition in chicken offspring with epigenetic modulation of SREBP2 and CYP7A1 genes.
  • Yun Hu
  • Yue Feng
  • Zequn Ding
  • Lilei Lv
  • Yi Sui
  • Qinwei Sun
  • Halima Abobaker
  • Demin Cai
  • Ruqian Zhao
  • Poult. Sci..2020 Jun;99(6):3111-3120. S0032-5791(20)30076-6. doi: 10.1016/j.psj.2019.12.058.Epub 2020-04-14.

16項目の変形性膝関節症患者教育質問票(KOPEQ)に基づいた7項目の膝関節置換術患者教育質問票(KR-PEQ-7)の検証

Validation of the 7-item knee replacement patient education questionnaire (KR-PEQ-7), based on the 16-item knee osteoarthritis patient education questionnaire (KOPEQ).
  • Erika O Huber
  • Axel Boger
  • André Meichtry
  • Caroline H Bastiaenen
  • BMC Musculoskelet Disord.2020 Jul;21(1):468. 10.1186/s12891-020-03476-y. doi: 10.1186/s12891-020-03476-y.Epub 2020-07-16.

凍結精子症の男性からの射精精精子を3個以下にするための改良透過性凍結精子無添加ガラス固化法と、この方法で生まれた14人の子供の7年間の追跡調査

Modified permeable cryoprotectant-free vitrification method for three or fewer ejaculated spermatozoa from cryptozoospermic men and 7-year follow-up study of 14 children born from this method.
  • Motoharu Ohno
  • Atsushi Tanaka
  • Motoi Nagayoshi
  • Takashi Yamaguchi
  • Youichi Takemoto
  • Izumi Tanaka
  • Seiji Watanabe
  • Atsuo Itakura
  • Hum. Reprod..2020 May;35(5):1019-1028. 5834445. doi: 10.1093/humrep/deaa072.

Affective Switch Associated Associated With Oral, Low Dose Ketamine Treatment in a Patient With Treatment Resistant Bipolar I Depression.症例報告と文献レビュー

Affective Switch Associated With Oral, Low Dose Ketamine Treatment in a Patient With Treatment Resistant Bipolar I Depression. Case Report and Literature Review.
  • Alina Wilkowska
  • Łukasz Szałach
  • Jakub Słupski
  • Aleksandra Wielewicka
  • Małgorzata Czarnota
  • Maria Gałuszko-Węgielnik
  • Mariusz S Wiglusz
  • Wiesław J Cubała
  • Front Psychiatry.2020;11:516. doi: 10.3389/fpsyt.2020.00516.Epub 2020-06-03.

入院患者における介護者による疼痛管理介入が患者、介護者、提供者、医療システムの転帰に及ぼす影響。システマティックレビュー

The effect of caregiver-facilitated pain management interventions in hospitalized patients on patient, caregiver, provider and health system outcomes: A systematic review.
  • Israt Yasmeen
  • Karla D Krewulak
  • Cherri Zhang
  • Henry T Stelfox
  • Kirsten M Fiest
  • J Pain Symptom Manage.2020 Jun;S0885-3924(20)30574-1. doi: 10.1016/j.jpainsymman.2020.06.030.Epub 2020-06-29.

石油系炭化水素に対するプランクトン群集の反応をカスタマイズした場合のエンドポイントとしての周期密度。毒性効果のレベルは、適切な時間スケールと一致させる必要がある

Periodic density as an endpoint of customized plankton community responses to petroleum hydrocarbons: A level of toxic effect should be matched with a suitable time scale.
  • Changyou Wang
  • Siwen Wang
  • Xinming Jiao
  • Bin Yang
  • Shengkang Liang
  • Zhuhua Luo
  • Longjiang Mao
  • Ecotoxicol. Environ. Saf..2020 Sep;201:110723. S0147-6513(20)30562-5. doi: 10.1016/j.ecoenv.2020.110723.Epub 2020-05-30.

外傷性脳損傷患者における選択的脳冷却用鼻咽頭カテーテルの有効性と安全性。プロスペクティブ、非ランダム化パイロット研究

Efficacy and Safety of a Nasopharyngeal Catheter for Selective Brain Cooling in Patients with Traumatic Brain Injury: A Prospective, Non-randomized Pilot Study.
  • Raphael Einsfeld Simões Ferreira
  • Bernardo Lembo Conde de Paiva
  • Flávio Geraldo Rezende de Freitas
  • Flávia Ribeiro Machado
  • Gisele Sampaio Silva
  • Rafael Mônaco Raposo
  • Conrado Feisthauer Silveira
  • Ricardo Silva Centeno
  • Neurocrit Care.2020 Jul;10.1007/s12028-020-01052-9. doi: 10.1007/s12028-020-01052-9.Epub 2020-07-17.

"実生活"多環芳香族炭化水素(PAH)混合物は、hCG、hPLおよびhPLGFレベルを調節し、ヒト胎盤細胞株におけるMMP-2/MMP-9比およびVEGF発現の生理的比率を混乱させる

"Real life" polycyclic aromatic hydrocarbon (PAH) mixtures modulate hCG, hPL and hPLGF levels and disrupt the physiological ratio of MMP-2 to MMP-9 and VEGF expression in human placenta cell lines.
  • Eliza Drwal
  • Agnieszka Rak
  • Wacław Tworzydło
  • Ewa Łucja Gregoraszczuk
  • Reprod. Toxicol..2020 Aug;95:1-10. S0890-6238(20)30019-8. doi: 10.1016/j.reprotox.2020.02.006.Epub 2020-05-11.

潜在クラス解析により同定された非ステロイド性抗炎症性疾患増悪性呼吸器疾患のサブフェノタイプ

Subphenotypes of nonsteroidal antiinflammatory disease-exacerbated respiratory disease identified by latent class analysis.
  • Natalia Celejewska-Wójcik
  • Krzysztof Wójcik
  • Maria Ignacak-Popiel
  • Adam Ćmiel
  • Katarzyna Tyrak
  • Anna Gielicz
  • Aleksander Kania
  • Paweł Nastałek
  • Marek Sanak
  • Lucyna Mastalerz
  • Allergy.2020 04;75(4):831-840. doi: 10.1111/all.14141.Epub 2020-01-28.

ヘキサクロロナフタレンは、活性酸素の産生促進機構を介してミトコンドリア依存性の神経毒性を誘導する

Hexachloronaphthalene Induces Mitochondrial-Dependent Neurotoxicity via a Mechanism of Enhanced Production of Reactive Oxygen Species.
  • Malwina Lisek
  • Joanna Stragierowicz
  • Feng Guo
  • Philipp P Prosseda
  • Magdalena Wiktorska
  • Bozena Ferenc
  • Anna Kilanowicz
  • Ludmila Zylinska
  • Tomasz Boczek
  • Oxid Med Cell Longev.2020;2020:2479234. doi: 10.1155/2020/2479234.Epub 2020-06-26.

IVA-B期の口腔咽頭癌または咽頭下癌患者を対象とした臓器温存療法としての体積変調アーク療法を用いた導入化学療法と化学放射線療法の長期治療成績の検討

Long-term outcomes of induction chemotherapy followed by chemoradiotherapy using volumetric-modulated arc therapy as an organ preservation approach in patients with stage IVA-B oropharyngeal or hypopharyngeal cancers.
  • Katsumaro Kubo
  • Yuji Murakami
  • Masahiro Kenjo
  • Nobuki Imano
  • Yuki Takeuchi
  • Ikuno Nishibuchi
  • Tomoki Kimura
  • Daisuke Kawahara
  • Tsutomu Ueda
  • Sachio Takeno
  • Yasushi Nagata
  • J. Radiat. Res..2020 Jul;61(4):554-562. 5858247. doi: 10.1093/jrr/rraa033.

ハンガリーの一般成人集団におけるeHealthリテラシーと患者報告による外来診療の経験の探索。横断的研究

Exploring eHealth Literacy and Patient-Reported Experiences with Outpatient Care in the Hungarian General Adult Population: A Cross-Sectional Study.
  • Zsombor Zrubka
  • Óscar Brito Fernandes
  • Petra Baji
  • Ottó Hajdu
  • Levente Kovács
  • Dionne Kringos
  • Niek Klazinga
  • László Gulácsi
  • Valentin Brodszky
  • Fanni Rencz
  • Márta Péntek
  • J. Med. Internet Res..2020 Jun;doi: 10.2196/19013.Epub 2020-06-15.

健康な白人患者における重度の外傷が引き金となった細菌性血管腫症.症例報告

Bacillary angiomatosis triggered by severe trauma in a healthy Caucasian patient: A case report.
  • Mihaela Balaban
  • Roxana Ioana Nedelcu
  • Gabriela Balmes
  • Teodora Adela Todorovic
  • Alice Brinzea
  • Luciana Nichita
  • Cristiana Gabriela Popp
  • Razvan Theodor Andrei
  • Sabina Andrada Zurac
  • Daniela Adriana Ion
  • Gabriela Turcu
  • Exp Ther Med.2020 Jul;20(1):56-60. ETM-0-0-8260. doi: 10.3892/etm.2019.8260.Epub 2019-11-29.

リボソームリサイクル反応のためのモデルポストターミネーション複合体(PoTC)の化学的・構造的特性評価RRFとEF-GによるmRNAの放出の証拠

Chemical and structural characterization of a model Post-Termination Complex (PoTC) for the ribosome recycling reaction: Evidence for the release of the mRNA by RRF and EF-G.
  • Nobuhiro Iwakura
  • Takeshi Yokoyama
  • Fabio Quaglia
  • Kaoru Mitsuoka
  • Kazuhiro Mio
  • Hideki Shigematsu
  • Mikako Shirouzu
  • Akira Kaji
  • Hideko Kaji
  • PLoS ONE.2017;12(5):e0177972. PONE-D-16-39755. doi: 10.1371/journal.pone.0177972.Epub 2017-05-24.

クエン酸第二鉄調節因子FecRは、ユニークなツインアルギニン輸送依存性メカニズムを介して細菌内膜を横断してトランスロケーションされている

Ferric Citrate Regulator FecR Is Translocated across the Bacterial Inner Membrane via a Unique Twin-Arginine Transport-Dependent Mechanism.
  • Ian J Passmore
  • Jennifer M Dow
  • Francesc Coll
  • Jon Cuccui
  • Tracy Palmer
  • Brendan W Wren
  • J. Bacteriol..2020 Apr;202(9). e00541-19. doi: 10.1128/JB.00541-19.Epub 2020-04-09.

柔軟性の高い高分解能質量分析アプローチによる都市排水中の新規精神活性物質のスクリーニング

Flexible high resolution-mass spectrometry approach for screening new psychoactive substances in urban wastewater.
  • Noelia Salgueiro-González
  • Sara Castiglioni
  • Emma Gracia-Lor
  • Lubertus Bijlsma
  • Alberto Celma
  • Renzo Bagnati
  • Félix Hernández
  • Ettore Zuccato
  • Sci. Total Environ..2019 Nov;689:679-690. S0048-9697(19)32909-2. doi: 10.1016/j.scitotenv.2019.06.336.Epub 2019-06-26.

エトリパミル点鼻スプレーによる上室性頻拍から副鼻腔リズムへの迅速変換

Etripamil Nasal Spray for Rapid Conversion of Supraventricular Tachycardia to Sinus Rhythm.
  • Bruce S Stambler
  • Paul Dorian
  • Philip T Sager
  • Douglas Wight
  • Philippe Douville
  • Diane Potvin
  • Pirouz Shamszad
  • Ronald J Haberman
  • Richard S Kuk
  • Dhanunjaya R Lakkireddy
  • Jose M Teixeira
  • Kenneth C Bilchick
  • Roger S Damle
  • Robert C Bernstein
  • Wilson W Lam
  • Gearoid O'Neill
  • Peter A Noseworthy
  • Kalpathi L Venkatachalam
  • Benoit Coutu
  • Blandine Mondésert
  • Francis Plat
  • J. Am. Coll. Cardiol..2018 07;72(5):489-497. S0735-1097(18)34992-1. doi: 10.1016/j.jacc.2018.04.082.

ガーナにおけるサルシパルム原虫ヒスチジンリッチプロテイン2の多様性

Plasmodium falciparum histidine-rich protein 2 diversity in Ghana.
  • Otchere Addai-Mensah
  • Bismarck Dinko
  • Mark Noagbe
  • Selassie Louis Ameke
  • Max Efui Annani-Akollor
  • Eddie-Williams Owiredu
  • Kofi Mensah
  • Richmond Tackie
  • Eliezer Togbe
  • Comfort Agyare-Kwabi
  • Charles Gyasi
  • Constance Adu-Gyamfi
  • Alexander Yaw Debrah
  • Malar. J..2020 Jul;19(1):256. 10.1186/s12936-020-03328-z. doi: 10.1186/s12936-020-03328-z.Epub 2020-07-16.

LC-MSおよびHS-SPME-GC-O-MSによるニュージーランド産4品種のフェジョア果汁中のフェノール化合物およびアロマ活性化合物の特性評価

Characterization of phenolic compounds and aroma active compounds in feijoa juice from four New Zealand grown cultivars by LC-MS and HS-SPME-GC-O-MS.
  • Yaoyao Peng
  • Karen Suzanne Bishop
  • Jingying Zhang
  • Donglin Chen
  • Siew Young Quek
  • Food Res. Int..2020 Mar;129:108873. S0963-9969(19)30759-8. doi: 10.1016/j.foodres.2019.108873.Epub 2019-12-05.

健康な小児1300人における三尖頭環状面収縮期エクスカーションと僧帽弁環状面収縮期エクスカーションの心臓基準値。単施設での結果

Tricuspid annular plane systolic excursion and mitral annular plane systolic excursion cardiac reference values in 1300 healthy children: Single-center results.
  • Mahmut Keskin
  • Özkan Kaya
  • Tamer Yoldaş
  • Selmin Karademir
  • Utku Arman Örün
  • Senem Özgür
  • Vehbi Doğan
  • Osman Gürdal
  • Echocardiography.2020 Jul;doi: 10.1111/echo.14793.Epub 2020-07-20.

COVID-19患者の治療における回復期血漿と間葉系幹細胞の相乗的役割:不顕性症例報告

A synergistic role of convalescent plasma and mesenchymal stem cells in the treatment of severely ill COVID-19 patients: a clinical case report.
  • Hongbing Peng
  • Tiefeng Gong
  • Xiaoying Huang
  • Xun Sun
  • Hong Luo
  • Weizhong Wang
  • Junbiao Luo
  • Baowei Luo
  • Yanhui Chen
  • Xingxing Wang
  • Haifeng Long
  • Hua Mei
  • Chuang Li
  • Yanni Dai
  • Honghui Li
  • Stem Cell Res Ther.2020 Jul;11(1):291. 10.1186/s13287-020-01802-8. doi: 10.1186/s13287-020-01802-8.Epub 2020-07-16.

CNS受容体への結合を低減した抗結核性ポリハロゲン化フェノチアジンおよびフェノセレナジン

Antitubercular polyhalogenated phenothiazines and phenoselenazine with reduced binding to CNS receptors.
  • Maria Giulia Nizi
  • Jenny Desantis
  • Yoshio Nakatani
  • Serena Massari
  • Maria Angela Mazzarella
  • Gauri Shetye
  • Stefano Sabatini
  • Maria Letizia Barreca
  • Giuseppe Manfroni
  • Tommaso Felicetti
  • Rowena Rushton-Green
  • Kiel Hards
  • Gniewomir Latacz
  • Grzegorz Satała
  • Andrzej J Bojarski
  • Violetta Cecchetti
  • Michal H Kolář
  • Jadwiga Handzlik
  • Gregory M Cook
  • Scott G Franzblau
  • Oriana Tabarrini
  • Eur J Med Chem.2020 Jun;201:112420. S0223-5234(20)30391-3. doi: 10.1016/j.ejmech.2020.112420.Epub 2020-06-05.