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日本語AIでPubMedを検索

日本語AIでPubMedを検索

PubMedの提供する医学論文データベースを日本語で検索できます。AI(Deep Learning)を活用した機械翻訳エンジンにより、精度高く日本語へ翻訳された論文をご参照いただけます。

みんなが読んでいる論文

没入型技術を活用して、コミュニティ設定でのオピオイド過剰摂取逆転訓練へのアクセスを拡大する。無作為化対照同等性試験の結果

Leveraging immersive technology to expand access to opioid overdose reversal training in community settings: Results from a randomized controlled equivalence trial.
  • Natalie Herbert
  • Sydney Axson
  • Leeann Siegel
  • Kyle Cassidy
  • Ann Marie Hoyt-Brennan
  • Clare Whitney
  • Allison Herens
  • Nicholas A Giordano
  • Drug Alcohol Depend.2020 Jul;214:108160. S0376-8716(20)30325-2. doi: 10.1016/j.drugalcdep.2020.108160.Epub 2020-07-02.

双極性障害におけるファーマコゲノミクスの潜在的標的:現在の検査の検討と治療選択を個別化するための意思決定支援ツールの開発

Potential pharmacogenomic targets in bipolar disorder: considerations for current testing and the development of decision support tools to individualize treatment selection.
  • Alfredo B Cuéllar-Barboza
  • Susan L McElroy
  • Marin Veldic
  • Balwinder Singh
  • Simon Kung
  • Francisco Romo-Nava
  • Nicolas A Nunez
  • Alejandra Cabello-Arreola
  • Brandon J Coombes
  • Miguel Prieto
  • Hannah K Betcher
  • Katherine M Moore
  • Stacey J Winham
  • Joanna M Biernacka
  • Mark A Frye
  • Int J Bipolar Disord.2020 Jul;8(1):23. 10.1186/s40345-020-00184-3. doi: 10.1186/s40345-020-00184-3.Epub 2020-07-04.

デュアル可溶性エポキシドヒドロラーゼ阻害剤/PPAR-γアゴニストは腎線維化を抑制する

Dual soluble epoxide hydrolase inhibitor/PPAR-γ agonist attenuates renal fibrosis.
  • Anna Stavniichuk
  • Md Abdul Hye Khan
  • Michael M Yeboah
  • Marla A Chesnik
  • Wojciech K Jankiewicz
  • Markus Hartmann
  • René Blöcher
  • Theresa Kircher
  • Olexiy Savchuk
  • Ewgenij Proschak
  • John D Imig
  • Prostaglandins Other Lipid Mediat..2020 Jun;150:106472. S1098-8823(20)30065-4. doi: 10.1016/j.prostaglandins.2020.106472.Epub 2020-06-20.

SPARCは肝動脈化学塞栓術後の予後と負の相関があり、ERK/MMPシグナル伝達経路を介して肝細胞癌の増殖と転移を促進する

SPARC Negatively Correlates With Prognosis After Transarterial Chemoembolization and Facilitates Proliferation and Metastasis of Hepatocellular Carcinoma via ERK/MMP Signaling Pathways.
  • Yao Liu
  • Ying Feng
  • Xiaojing Wang
  • Xue Yang
  • Ying Hu
  • Yuxin Li
  • Qun Zhang
  • Yunyi Huang
  • Ke Shi
  • Chongping Ran
  • Jie Hou
  • Li Jiang
  • Junfa Li
  • Xianbo Wang
  • Front Oncol.2020;10:813. doi: 10.3389/fonc.2020.00813.Epub 2020-05-21.

山火事後の北極圏ツンドラへの北方高木の転入に対する菌根菌の接種の全体的な影響は限定的であり、種特異的な反応を示した

Limited overall impacts of ectomycorrhizal inoculation on recruitment of boreal trees into Arctic tundra following wildfire belie species-specific responses.
  • Rebecca E Hewitt
  • F Stuart Chapin
  • Teresa N Hollingsworth
  • Michelle C Mack
  • Adrian V Rocha
  • D Lee Taylor
  • PLoS ONE.2020;15(7):e0235932. PONE-D-20-09652. doi: 10.1371/journal.pone.0235932.Epub 2020-07-09.

医学雑誌に投稿された仕事の開示書:医学雑誌編集者国際委員会からの提案

A disclosure form for work submitted to medical journals: a proposal from the International Committee of Medical Journal Editors.
  • Darren B Taichman
  • Joyce Backus
  • Christopher Baethge
  • Howard Bauchner
  • Annette Flanagin
  • Fernando Florenzano
  • Frank A Frizelle
  • Fiona Godlee
  • Laragh Gollogly
  • Abraham Haileamlak
  • Sung-Tae Hong
  • Richard Horton
  • Astrid James
  • Christine Laine
  • Pamela W Miller
  • Anja Pinborg
  • Eric J Rubin
  • Peush Sahni
  • N. Z. Med. J..2020 02;133(1509):6-8. Epub 2020-02-07.

機能化されたPHB顆粒は、組換えバチルス・メガテリウムのコレステロールとアナログの効率的な側鎖切断のための基礎を提供します

Functionalized PHB granules provide the basis for the efficient side-chain cleavage of cholesterol and analogs in recombinant Bacillus megaterium.
  • Adrian Gerber
  • Michael Kleser
  • Rebekka Biedendieck
  • Rita Bernhardt
  • Frank Hannemann
  • Microb. Cell Fact..2015 Jul;14:107. 10.1186/s12934-015-0300-y. doi: 10.1186/s12934-015-0300-y.Epub 2015-07-29.

インスリノーマ局在化のための低用量選択的動脈カルシウム刺激試験:単施設での連続5症例の経験

Low-dose Selective Arterial Calcium Stimulation Test for Localizing Insulinoma: A Single-center Experience of Five Consecutive Cases.
  • Tomonobu Hatoko
  • Takaaki Murakami
  • Masakatsu Sone
  • Daisuke Yabe
  • Toshihiko Masui
  • Yuji Nakamoto
  • Akihiro Furuta
  • Norimitsu Uza
  • Yuzo Kodama
  • Norio Harada
  • Masahito Ogura
  • Akihiro Yasoda
  • Nobuya Inagaki
  • Intern. Med..2020 Jun;doi: 10.2169/internalmedicine.4396-20.Epub 2020-06-30.

転移性去勢抵抗性前立腺癌の転移時の原発病変再生検におけるAKR1C3発現は、第一選択療法としてのアビラテロンの有効性の低さと強く関連している

AKR1C3 expression in primary lesion rebiopsy at the time of metastatic castration-resistant prostate cancer is strongly associated with poor efficacy of abiraterone as a first-line therapy.
  • Jinge Zhao
  • Mengni Zhang
  • Jiandong Liu
  • Zhenhua Liu
  • Pengfei Shen
  • Ling Nie
  • Wenhao Guo
  • Diming Cai
  • Jiyan Liu
  • Cameron M Armstrong
  • Guangxi Sun
  • Junru Chen
  • Sha Zhu
  • Jindong Dai
  • Haoran Zhang
  • Peng Zhao
  • Xingming Zhang
  • Xiaoxue Yin
  • Xudong Zhu
  • Yuchao Ni
  • Ni Chen
  • Hao Zeng
  • Prostate.2019 09;79(13):1553-1562. doi: 10.1002/pros.23875.Epub 2019-07-11.

また、牛骨ミネラルとコラーゲン膜で覆われた自家製下顎骨ブロックを使用して移植された隆起部にインプラントを埋入した場合の10年間の平均追跡調査をレトロスペクティブに行った

A retrospective 10-year mean follow-up of implants placed in ridges grafted using autogenous mandibular blocks covered with bovine bone mineral and collagen membrane.
  • Matteo Chiapasco
  • Grazia Tommasato
  • David Palombo
  • Massimo Del Fabbro
  • Clin Oral Implants Res.2020 Apr;31(4):328-340. doi: 10.1111/clr.13571.Epub 2020-01-20.

ジンセノサイド化合物-MC1は、AMP活性化プロテインキナーゼ依存性機構を介して心筋細胞の酸化ストレスとアポトーシスを減少させる

Ginsenoside compound-Mc1 attenuates oxidative stress and apoptosis in cardiomyocytes through an AMP-activated protein kinase-dependent mechanism.
  • So-Hyeon Hong
  • Hwan-Jin Hwang
  • Joo Won Kim
  • Jung A Kim
  • You Bin Lee
  • Eun Roh
  • Kyung Mook Choi
  • Sei Hyun Baik
  • Hye Jin Yoo
  • J Ginseng Res.2020 Jul;44(4):664-671. S1226-8453(18)30420-2. doi: 10.1016/j.jgr.2019.08.006.Epub 2019-08-26.

腸球のブラシ境界の組み立てを促進するために、接着複合体の足場であるANKS4Bを先端微小絨毛に標的としている

A cryptic sequence targets the adhesion complex scaffold ANKS4B to apical microvilli to promote enterocyte brush border assembly.
  • Maura J Graves
  • Samaneh Matoo
  • Myoung Soo Choi
  • Zachary A Storad
  • Rawnag A El Sheikh Idris
  • Brooke K Pickles
  • Prashun Acharya
  • Paula E Shinder
  • Taylen O Arvay
  • Scott William Crawley
  • J. Biol. Chem..2020 Jul;jbc.RA120.013790. doi: 10.1074/jbc.RA120.013790.Epub 2020-07-06.

心房細動と上室性不整脈の治療のためのカテーテルアブレーションは透視検査の使用なしに。急性の有効性と安全性

Catheter Ablation for Treatment of Atrial Fibrillation and Supraventricular Arrhythmias Without Fluoroscopy Use: Acute Efficacy and Safety.
  • Eduardo B Saad
  • Charles Slater
  • Luiz Antonio Oliveira Inácio
  • Gustavo Vignoli Dos Santos
  • Lucas Carvalho Dias
  • Luiz Eduardo Montenegro Camanho
  • Arq. Bras. Cardiol..2020 Jun;114(6):1015-1026. S0066-782X2020000701015. doi: 10.36660/abc.20200096.Epub 2020-07-03.

RLBP1網膜色素変性症(RLBP1 RP)の患者体験をよりよく理解し、患者が報告したアウトカム(PRO)を評価するための質的面接

Qualitative Interviews to Better Understand the Patient Experience and Evaluate Patient-Reported Outcomes (PRO) in RLBP1 Retinitis Pigmentosa (RLBP1 RP).
  • Jane Green
  • Chloe Tolley
  • Sarah Bentley
  • Rob Arbuckle
  • Marie Burstedt
  • James Whelan
  • Karen Holopigian
  • Kali Stasi
  • Brigitte Sloesen
  • Claudio Spera
  • Jean-Yves Deslandes
  • Anmol Mullins
  • Adv Ther.2020 Jun;37(6):2884-2901. 10.1007/s12325-020-01275-4. doi: 10.1007/s12325-020-01275-4.Epub 2020-05-05.

潰瘍性大腸炎とクローン病の組織標本におけるアルド-ケト還元酵素ファミリー1メンバーC3の違いをマイクロプロテオミクスと免疫組織化学で明らかにした

Microproteomics and Immunohistochemistry Reveal Differences in Aldo-Keto Reductase Family 1 Member C3 in Tissue Specimens of Ulcerative Colitis and Crohn's Disease.
  • Karim Arafah
  • Mark Kriegsmann
  • Marcus Renner
  • Felix Lasitschka
  • Margaux Fresnais
  • Katharina Kriegsmann
  • Moritz von Winterfeld
  • Benjamin Goeppert
  • Jörg Kriegsmann
  • Rita Casadonte
  • Daniel Kazdal
  • Philippe Bulet
  • Rémi Longuespée
  • Proteomics Clin Appl.2020 Jul;14(4):e1900110. doi: 10.1002/prca.201900110.Epub 2020-02-16.

プロテインホスファターゼ2A阻害剤CIP2A, SET, PME-1の3つのタンパク質が媒介するリン酸化プロテオームと薬剤応答効果

Phosphoproteome and drug-response effects mediated by the three protein phosphatase 2A inhibitor proteins CIP2A, SET, and PME-1.
  • Otto Kauko
  • Susumu Y Imanishi
  • Evgeny Kulesskiy
  • Laxman Yetukuri
  • Teemu Daniel Laajala
  • Mukund Sharma
  • Karolina Pavic
  • Anna Aakula
  • Christian Rupp
  • Mikael Jumppanen
  • Pekka Haapaniemi
  • Luyao Ruan
  • Bhagwan Yadav
  • Veronika Suni
  • Taru Varila
  • Garry L Corthals
  • Jüri Reimand
  • Krister Wennerberg
  • Tero Aittokallio
  • Jukka Westermarck
  • J. Biol. Chem..2020 Mar;295(13):4194-4211. RA119.011265. doi: 10.1074/jbc.RA119.011265.Epub 2020-02-18.

内皮がチェロノイディス・カルボナリア大動脈の電場刺激誘発収縮を調節する

Endothelium modulates electrical field stimulation-induced contractions of Chelonoidis carbonaria aortic rings.
  • Rafael Campos
  • Felipe Fernandes Jacintho
  • José Britto-Júnior
  • Fabíola Z Mónica
  • Alberto Fernando Oliveira Justo
  • André Sampaio Pupo
  • Ronilson Agnaldo Moreno
  • Valéria Barbosa de Souza
  • André Almeida Schenka
  • Edson Antunes
  • Gilberto De Nucci
  • Comp. Biochem. Physiol. C Toxicol. Pharmacol..2020 Jul;233:108763. S1532-0456(20)30063-6. doi: 10.1016/j.cbpc.2020.108763.Epub 2020-04-11.

免疫療法を試験するためのヒト化マウスNPC-PDXモデルの確立と特性評価

Establishment and Characterization of Humanized Mouse NPC-PDX Model for Testing Immunotherapy.
  • Wai Nam Liu
  • Shin Yie Fong
  • Wilson Wei Sheng Tan
  • Sue Yee Tan
  • Min Liu
  • Jia Ying Cheng
  • Sherlly Lim
  • Lisda Suteja
  • Edwin Kunxiang Huang
  • Jerry Kok Yen Chan
  • Narayanan Gopalakrishna Iyer
  • Joe Poh Sheng Yeong
  • Darren Wan-Teck Lim
  • Qingfeng Chen
  • Cancers (Basel).2020 Apr;12(4). E1025. doi: 10.3390/cancers12041025.Epub 2020-04-22.

乳酸脱水素酵素阻害はIL-21と相乗的に作用し、CD8 T細胞の幹細胞化と抗腫瘍免疫を促進する

Lactate dehydrogenase inhibition synergizes with IL-21 to promote CD8 T cell stemness and antitumor immunity.
  • Dalton Hermans
  • Sanjivan Gautam
  • Juan C García-Cañaveras
  • Daniel Gromer
  • Suman Mitra
  • Rosanne Spolski
  • Peng Li
  • Stephen Christensen
  • Rosa Nguyen
  • Jian-Xin Lin
  • Jangsuk Oh
  • Ning Du
  • Sharon Veenbergen
  • Jessica Fioravanti
  • Risa Ebina-Shibuya
  • Christopher Bleck
  • Leonard M Neckers
  • Joshua D Rabinowitz
  • Luca Gattinoni
  • Warren J Leonard
  • Proc. Natl. Acad. Sci. U.S.A..2020 03;117(11):6047-6055. 1920413117. doi: 10.1073/pnas.1920413117.Epub 2020-03-02.

アビラテロンとプレドニゾンによる治療を受けた転移性ホルモン感受性前立腺がん患者における前立腺表面抗原の変化パターンの特定

Identifying Prostate Surface Antigen Patterns of Change in Patients with Metastatic Hormone Sensitive Prostate Cancer Treated with Abiraterone and Prednisone.
  • Iris Y Sheng
  • Jaleh Fallah
  • Ruby Gupta
  • Hong Li
  • Kimberly Allman
  • Allison Martin
  • Pedro Barata
  • Moshe C Ornstein
  • Timothy D Gilligan
  • Brian I Rini
  • Jorge A Garcia
  • Target Oncol.2020 Jul;10.1007/s11523-020-00734-w. doi: 10.1007/s11523-020-00734-w.Epub 2020-07-13.

ナタネ茎のSclerotinia sclerotiorumに対する抵抗性の向上とナタネ藁由来の溶存有機物の菌糸体上での阻害に対する土壌中のセレンの強化と改善

Enhancement and improvement of selenium in soil to the resistance of rape stem against Sclerotinia sclerotiorum and the inhibition of dissolved organic matter derived from rape straw on mycelium.
  • Qin Cheng
  • Wei Jia
  • Chengxiao Hu
  • Guangyu Shi
  • Dandan Yang
  • Miaomiao Cai
  • Ting Zhan
  • Yanni Tang
  • Yingjie Zhou
  • Xuecheng Sun
  • Xiaohu Zhao
  • Environ. Pollut..2020 May;265(Pt A):114827. S0269-7491(20)30775-2. doi: 10.1016/j.envpol.2020.114827.Epub 2020-05-19.

ホルモン受容体陽性転移性乳癌患者におけるパルボシクリブの早期投与量の強度低下が臨床転帰に及ぼす影響

Impact of early dose intensity reduction of Palbociclib on clinical outcomes in patients with hormone-receptor-positive metastatic breast cancer.
  • Bahar Moftakhar
  • Manidhar Lekkala
  • Myla Strawderman
  • Tae C Smith
  • Philip Meacham
  • Bryan Fitzgerald
  • Carla I Falkson
  • Ajay Dhakal
  • Breast Cancer Res. Treat..2020 Jul;10.1007/s10549-020-05793-1. doi: 10.1007/s10549-020-05793-1.Epub 2020-07-15.

感覚野を供給する動脈上に増殖した未破裂のGemella Morbillorum感染性動脈瘤に対するY字型動脈グラフトを用いた頭蓋内バイパス術.症例報告

Intracranial-Intracranial Bypass Using a "Y"-Shaped Artery Graft for Growing Unruptured Gemella Morbillorum Infectious Aneurysm on Artery Supplying Sensory Cortex: A Case Report.
  • Masato Shiba
  • Naoki Toma
  • Munenari Ikezawa
  • Yusuke Kuroda
  • Yume Suzuki
  • Reona Asada
  • Yoichi Miura
  • Ryuta Yasuda
  • Hidenori Suzuki
  • World Neurosurg.2020 Jul;S1878-8750(20)31577-1. doi: 10.1016/j.wneu.2020.07.056.Epub 2020-07-16.