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日本語AIでPubMedを検索

日本語AIでPubMedを検索

PubMedの提供する医学論文データベースを日本語で検索できます。AI(Deep Learning)を活用した機械翻訳エンジンにより、精度高く日本語へ翻訳された論文をご参照いただけます。

みんなが読んでいる論文

トリプルネガティブ乳がん細胞における抗増殖遺伝子B細胞転座遺伝子2によるTwist1発現のトランスレーショナルダウンレギュレーション

Translational downregulation of Twist1 expression by antiproliferative gene, B-cell translocation gene 2, in the triple negative breast cancer cells.
  • Preethi Devanand
  • Santhoshkumar Sundaramoorthy
  • Min Sook Ryu
  • Aravinth Kumar Jayabalan
  • Takbum Ohn
  • In Kyoung Lim
  • Cell Death Dis.2019 05;10(6):410. 10.1038/s41419-019-1640-z. doi: 10.1038/s41419-019-1640-z.Epub 2019-05-28.

減衰全反射-フーリエ変換赤外分光法とケモメトリクスによるヘロイン、メタンフェタミン、ケタミンおよびそれらの添加物の分類

Classification of heroin, methamphetamine, ketamine and their additives by attenuated total reflection-Fourier transform infrared spectroscopy and chemometrics.
  • Xinlong He
  • Jifen Wang
  • Xinwei You
  • Fan Niu
  • Linyuan Fan
  • Yufan Lv
  • Spectrochim Acta A Mol Biomol Spectrosc.2020 Jul;241:118665. S1386-1425(20)30644-2. doi: 10.1016/j.saa.2020.118665.Epub 2020-07-11.

強力な抗ライシュマニア活性を有する8-ヒドロキシナフチリジンの同定と最適化。初期SARと活性の評価

Identification and optimisation of a series of 8-hydroxy naphthyridines with potent antileishmanial activity: Initial SAR and assessment of activity.
  • Michael Thomas
  • Manu De Rycker
  • Richard J Wall
  • Daniel Spinks
  • Ola Epemolu
  • Sujatha Manthri
  • Suzanne Norval
  • Maria Osuna-Cabello
  • Stephen Patterson
  • Jennifer Riley
  • Frederick R C Simeons
  • Laste Stojanovski
  • John Thomas
  • Stephen Thompson
  • Claire Naylor
  • Jose M Fiandor
  • Paul G Wyatt
  • Maria Marco
  • Susan Wyllie
  • Kevin D Read
  • Timothy J Miles
  • Ian H Gilbert
  • J. Med. Chem..2020 Jul;doi: 10.1021/acs.jmedchem.0c00705.Epub 2020-07-14.

S100A9は、TLR4/TNF経路を介して帯状疱疹神経痛のマウスモデルにおいて重要な役割を果たしています

S100A9 plays a pivotal role in a mouse model of herpetic neuralgia via TLR4/TNF pathway.
  • Cássia R Silva
  • Bruno M S Melo
  • Jaqueline R Silva
  • Alexandre H Lopes
  • Janaina A Pereira
  • Nerry T Cecilio
  • Jonilson Berlink
  • Giovani G Souza
  • Guilherme Lucas
  • Thomas Vogl
  • Fernando Q Cunha
  • José C Alves-Filho
  • Thiago M Cunha
  • Brain Behav. Immun..2020 Mar;S0889-1591(19)31492-8. doi: 10.1016/j.bbi.2020.03.033.Epub 2020-03-31.

副甲状腺ホルモン、1.25(OH)D、および線維芽細胞増殖因子 23 が産卵鶏のさまざまな組織におけるカルシウム代謝を制御する遺伝子に及ぼす可能性のある役割

Possible roles of parathyroid hormone, 1.25(OH)D, and fibroblast growth factor 23 on genes controlling calcium metabolism across different tissues of the laying hen.
  • A Gloux
  • N Le Roy
  • J Ezagal
  • N Même
  • C Hennequet-Antier
  • M L Piketty
  • D Prié
  • G Benzoni
  • J Gautron
  • Y Nys
  • A Narcy
  • M J Duclos
  • Domest. Anim. Endocrinol..2020 Jul;72:106407. S0739-7240(19)30086-4. doi: 10.1016/j.domaniend.2019.106407.Epub 2019-10-23.

パラス女性における骨盤底筋と尿失禁の治療に対する高強度集束電磁技術と電気刺激の効果に関する比較研究。治療後のデータの分析

A Comparative Study on the Effects of High-Intensity Focused Electromagnetic Technology and Electrostimulation for the Treatment of Pelvic Floor Muscles and Urinary Incontinence in Parous Women: Analysis of Posttreatment Data.
  • Elena Silantyeva
  • Dragana Zarkovic
  • Evgeniia Astafeva
  • Ramina Soldatskaia
  • Mekan Orazov
  • Marina Belkovskaya
  • Mark Kurtser
  • Female Pelvic Med Reconstr Surg.2020 Jan;doi: 10.1097/SPV.0000000000000807.Epub 2020-01-25.

血小板が豊富な血漿(PRP)は、血管新生とコラーゲン合成を促進することで、マウスの膝蓋腱の治癒を促進します

Platelet-rich plasma (PRP) accelerates murine patellar tendon healing through enhancement of angiogenesis and collagen synthesis.
  • Yohei Kobayashi
  • Yoshitomo Saita
  • Tomoiku Takaku
  • Tomomasa Yokomizo
  • Hirofumi Nishio
  • Hiroshi Ikeda
  • Yuji Takazawa
  • Masashi Nagao
  • Kazuo Kaneko
  • Norio Komatsu
  • J Exp Orthop.2020 Jul;7(1):49. 10.1186/s40634-020-00267-1. doi: 10.1186/s40634-020-00267-1.Epub 2020-07-08.

ドイツ領北海(北海)の一般的な洋上風力発電所の基礎に生息する移動性海底メガファウナ - 展開から2年後、Cancer pagurusの生産量が増加している

Mobile demersal megafauna at common offshore wind turbine foundations in the German Bight (North Sea) two years after deployment - increased production rate of Cancer pagurus.
  • R Krone
  • G Dederer
  • P Kanstinger
  • P Krämer
  • C Schneider
  • I Schmalenbach
  • Mar. Environ. Res..2017 Feb;123:53-61. S0141-1136(16)30301-4. doi: 10.1016/j.marenvres.2016.11.011.Epub 2016-11-29.

p21 の過剰発現は、細胞周期制御を介して CD43+細胞の生成を阻害することで、ヒト造血に抑制効果がある

Overexpression of p21 Has Inhibitory Effect on Human Hematopoiesis by Blocking Generation of CD43+ Cells via Cell-Cycle Regulation.
  • Jiahui Zeng
  • Huifang Zhang
  • Yuanling Liu
  • Wencui Sun
  • Danying Yi
  • Lijiao Zhu
  • Yonggang Zhang
  • Xu Pan
  • Yijing Chen
  • Ya Zhou
  • Guohui Bian
  • Mowen Lai
  • Qiongxiu Zhou
  • Jiaxin Liu
  • Bo Chen
  • Feng Ma
  • Int J Stem Cells.2020 Jul;13(2):202-211. ijsc20033. doi: 10.15283/ijsc20033.

バキュロウイルス蛋白質発現系を用いた生きた昆虫細胞の蛋白質の高分解能異核多次元NMR

High-resolution heteronuclear multidimensional NMR of proteins in living insect cells using a baculovirus protein expression system.
  • Jumpei Hamatsu
  • Daniel O'Donovan
  • Takashi Tanaka
  • Takahiro Shirai
  • Yuichiro Hourai
  • Tsutomu Mikawa
  • Teppei Ikeya
  • Masaki Mishima
  • Wayne Boucher
  • Brian O Smith
  • Ernest D Laue
  • Masahiro Shirakawa
  • Yutaka Ito
  • J. Am. Chem. Soc..2013 Feb;135(5):1688-91. doi: 10.1021/ja310928u.Epub 2013-01-27.

DNA複製タンパク質Cdc45は、Leishmania donovaniのPIPボックスを介してPCNAと直接相互作用し、Cdc45のPIPボックスは細胞の生存に不可欠である

DNA replication protein Cdc45 directly interacts with PCNA via its PIP box in Leishmania donovani and the Cdc45 PIP box is essential for cell survival.
  • Aarti Yadav
  • Varshni Sharma
  • Jyoti Pal
  • Pallavi Gulati
  • Manisha Goel
  • Udita Chandra
  • Neha Bansal
  • Swati Saha
  • PLoS Pathog..2020 05;16(5):e1008190. PPATHOGENS-D-19-02030. doi: 10.1371/journal.ppat.1008190.Epub 2020-05-15.

良性家族性乳児性痙攣:2q24番染色体上の新規遺伝子座のマッピングと遺伝的異質性の証拠

Benign familial infantile convulsions: mapping of a novel locus on chromosome 2q24 and evidence for genetic heterogeneity.
  • M Malacarne
  • E Gennaro
  • F Madia
  • S Pozzi
  • D Vacca
  • B Barone
  • B dalla Bernardina
  • A Bianchi
  • P Bonanni
  • P De Marco
  • A Gambardella
  • L Giordano
  • M L Lispi
  • A Romeo
  • E Santorum
  • F Vanadia
  • M Vecchi
  • P Veggiotti
  • F Vigevano
  • F Viri
  • F D Bricarelli
  • F Zara
  • Am. J. Hum. Genet..2001 Jun;68(6):1521-6. S0002-9297(07)61064-7. doi: 10.1086/320596.Epub 2001-04-20.

開口緑内障および眼圧亢進症に対するビマトプロストインプラントの第3相無作為化20ヵ月間試験(ARTEMIS 1)

Phase 3, Randomized, 20-Month Study of Bimatoprost Implant in Open-Angle Glaucoma and Ocular Hypertension (ARTEMIS 1).
  • Felipe A Medeiros
  • Thomas R Walters
  • Miriam Kolko
  • Michael Coote
  • Marina Bejanian
  • Margot L Goodkin
  • Qiang Guo
  • Jane Zhang
  • Michael R Robinson
  • Robert N Weinreb
  • Ophthalmology.2020 Jun;S0161-6420(20)30555-8. doi: 10.1016/j.ophtha.2020.06.018.Epub 2020-06-13.

数学的に導かれたアプローチを用いて、マウスモデルにおけるキメラ抗原受容体T細胞の投与数を減少させる

Less is more: reducing the number of administered chimeric antigen receptor T cells in a mouse model using a mathematically guided approach.
  • Anat Globerson Levin
  • Natalie Kronik
  • Tamar Shiloach
  • Tova Waks
  • Zelig Eshhar
  • Vladimir Vainstein
  • Cancer Immunol. Immunother..2020 Jul;69(7):1165-1175. 10.1007/s00262-020-02516-9. doi: 10.1007/s00262-020-02516-9.Epub 2020-03-04.

LQFM126プロトタイプのB16F10メラノーマ細胞に対する抗血管新生・抗腫瘍活性

Antiangiogenic and antitumoral activity of LQFM126 prototype against B16F10 melanoma cells.
  • Artur Christian Garcia da Silva
  • Bruna Dos Santos Rodrigues
  • Wanessa Machado Andrade
  • Thaís Rosa Marques Dos Santos
  • Flávio Silva de Carvalho
  • Germán Sanz
  • Boniek G Vaz
  • Luciano M Lião
  • Ricardo Menegatti
  • Marize Campos Valadares
  • Chem. Biol. Interact..2020 Jul;325:109127. S0009-2797(20)30404-X. doi: 10.1016/j.cbi.2020.109127.Epub 2020-05-11.

穴が多ければコントラストが上がる?心臓CTにおける18ゲージの非開孔カテーテルと22ゲージの開孔カテーテルの比較

More holes, more contrast? Comparing an 18-gauge non-fenestrated catheter with a 22-gauge fenestrated catheter for cardiac CT.
  • Andreas Marco Fischer
  • Philipp Riffel
  • Thomas Henzler
  • U Joseph Schoepf
  • Andres F Abadia
  • Richard Robert Bayer
  • Holger Haubenreisser
  • Dante Giovagnoli
  • Alexander Kremer
  • Stefan O Schoenberg
  • Joshua Gawlitza
  • PLoS ONE.2020;15(6):e0234311. PONE-D-19-24782. doi: 10.1371/journal.pone.0234311.Epub 2020-06-08.

雄性ラットにおける片側慢性拘縮損傷による能動相随意輪走の抑制。TLR4またはP2X7アンタゴニストにモルヒネを短時間投与した場合の持続的な治療効果

Suppression of active phase voluntary wheel running in male rats by unilateral chronic constriction injury: Enduring therapeutic effects of a brief treatment of morphine combined with TLR4 or P2X7 antagonists.
  • Suzanne M Green-Fulgham
  • Jayson B Ball
  • Steven F Maier
  • Kenner C Rice
  • Linda R Watkins
  • Peter M Grace
  • J. Neurosci. Res..2020 Jun;doi: 10.1002/jnr.24645.Epub 2020-06-13.

バングラデシュ農村部の幼い子供たちの呼吸器疾患に対する水質、衛生、衛生、栄養改善の効果。多施設クラスター無作為化対照試験

Effect of Improved Water Quality, Sanitation, Hygiene and Nutrition Interventions on Respiratory Illness in Young Children in Rural Bangladesh: A Multi-Arm Cluster-Randomized Controlled Trial.
  • Sania Ashraf
  • Mahfuza Islam
  • Leanne Unicomb
  • Mahbubur Rahman
  • Peter J Winch
  • Benjamin F Arnold
  • Jade Benjamin-Chung
  • Pavani K Ram
  • John M Colford
  • Stephen P Luby
  • Am. J. Trop. Med. Hyg..2020 05;102(5):1124-1130. doi: 10.4269/ajtmh.19-0769.

MicroRNA-10aは概日時計遺伝子の発現低下を介してC型肝炎ウイルス関連肝硬変の肝代謝を損なう 脳と筋肉のアリール炭化水素受容体核トランスロケーター-Like 1

MicroRNA-10a Impairs Liver Metabolism in Hepatitis C Virus-Related Cirrhosis Through Deregulation of the Circadian Clock Gene Brain and Muscle Aryl Hydrocarbon Receptor Nuclear Translocator-Like 1.
  • Rika Horii
  • Masao Honda
  • Takayoshi Shirasaki
  • Tetsuro Shimakami
  • Ryogo Shimizu
  • Souma Yamanaka
  • Kazuhisa Murai
  • Kazunori Kawaguchi
  • Kuniaki Arai
  • Tatsuya Yamashita
  • Yoshio Sakai
  • Taro Yamashita
  • Hikari Okada
  • Mikiko Nakamura
  • Eishiro Mizukoshi
  • Shuichi Kaneko
  • Hepatol Commun.2019 Dec;3(12):1687-1703. HEP41431. doi: 10.1002/hep4.1431.Epub 2019-09-26.

強く閉じ込められたペロブスカイト量子ドットをベースとした青色LED用バイポーラ・シェル・リサーフェシング

Bipolar-shell resurfacing for blue LEDs based on strongly confined perovskite quantum dots.
  • Yitong Dong
  • Ya-Kun Wang
  • Fanglong Yuan
  • Andrew Johnston
  • Yuan Liu
  • Dongxin Ma
  • Min-Jae Choi
  • Bin Chen
  • Mahshid Chekini
  • Se-Woong Baek
  • Laxmi Kishore Sagar
  • James Fan
  • Yi Hou
  • Mingjian Wu
  • Seungjin Lee
  • Bin Sun
  • Sjoerd Hoogland
  • Rafael Quintero-Bermudez
  • Hinako Ebe
  • Petar Todorovic
  • Filip Dinic
  • Peicheng Li
  • Hao Ting Kung
  • Makhsud I Saidaminov
  • Eugenia Kumacheva
  • Erdmann Spiecker
  • Liang-Sheng Liao
  • Oleksandr Voznyy
  • Zheng-Hong Lu
  • Edward H Sargent
  • Nat Nanotechnol.2020 Jul;10.1038/s41565-020-0714-5. doi: 10.1038/s41565-020-0714-5.Epub 2020-07-06.

Hunigの塩基は、強力な抗酸化剤および2HCK酵素増殖阻害剤としての新規な1-(2,3-ジヒドロ-1H-インデン-1-イル)-3-アリール尿素/チオ尿素誘導体の合成を触媒した

Hunig's base catalyzed synthesis of new 1-(2,3-dihydro-1H-inden-1-yl)-3-aryl urea/thiourea derivatives as potent antioxidants and 2HCK enzyme growth inhibitors.
  • Venkataramana Lachhi Reddy
  • Vijay Kumar Reddy Avula
  • Grigoriy V Zyryanov
  • Swetha Vallela
  • Jaya Shree Anireddy
  • Visweswara Rao Pasupuleti
  • Naga Raju Chamarthi
  • Bioorg. Chem..2020 Jan;95:103558. S0045-2068(19)31680-3. doi: 10.1016/j.bioorg.2019.103558.Epub 2019-12-29.