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日本語AIでPubMedを検索

日本語AIでPubMedを検索

PubMedの提供する医学論文データベースを日本語で検索できます。AI(Deep Learning)を活用した機械翻訳エンジンにより、精度高く日本語へ翻訳された論文をご参照いただけます。

みんなが読んでいる論文

脱コロニー化ではなく疾患予防-多剤耐性菌をコロニー化した患者における糞便性微生物叢移植のモデル

Disease prevention not decolonization - a model for fecal microbiota transplantation in patients colonized with multidrug-resistant organisms.
  • Rohma Ghani
  • Benjamin H Mullish
  • Julie A K McDonald
  • Anan Ghazy
  • Horace R T Williams
  • Eimear T Brannigan
  • Siddharth Mookerjee
  • Giovanni Satta
  • Mark Gilchrist
  • Neill Duncan
  • Richard Corbett
  • Andrew J Innes
  • Jiří Pavlů
  • Mark R Thursz
  • Frances Davies
  • Julian R Marchesi
  • Clin. Infect. Dis..2020 Jul;ciaa948. doi: 10.1093/cid/ciaa948.Epub 2020-07-18.

Ni(II), Cu(II), Co(II)を用いた二次元MOFの効率的な酸素発生電極触媒としての性能.触媒性能とMOFの構造とレドックスカップリングのポテンシャルの合理化

2D- MOFs with Ni(II), Cu(II) and Co(II) as Efficient Oxygen Evolution Electrocatalysts: Rationalization of Catalytic Performance vs Structure of the MOFs and Potential of the Redox Couples.
  • Anindita Goswami
  • Debanjali Ghosh
  • Vladimir V Chernyshev
  • Avishek Dey
  • Debabrata Pradhan
  • Kumar Biradha
  • ACS Appl Mater Interfaces.2020 Jul;doi: 10.1021/acsami.0c07268.Epub 2020-07-07.

COVID-19患者の詳細な免疫プロファイリングにより、治療上の意味を持つ異なる免疫型が明らかになった

Deep immune profiling of COVID-19 patients reveals distinct immunotypes with therapeutic implications.
  • Divij Mathew
  • Josephine R Giles
  • Amy E Baxter
  • Derek A Oldridge
  • Allison R Greenplate
  • Jennifer E Wu
  • Cécile Alanio
  • Leticia Kuri-Cervantes
  • M Betina Pampena
  • Kurt D'Andrea
  • Sasikanth Manne
  • Zeyu Chen
  • Yinghui Jane Huang
  • John P Reilly
  • Ariel R Weisman
  • Caroline A G Ittner
  • Oliva Kuthuru
  • Jeanette Dougherty
  • Kito Nzingha
  • Nicholas Han
  • Justin Kim
  • Ajinkya Pattekar
  • Eileen C Goodwin
  • Elizabeth M Anderson
  • Madison E Weirick
  • Sigrid Gouma
  • Claudia P Arevalo
  • Marcus J Bolton
  • Fang Chen
  • Simon F Lacey
  • Holly Ramage
  • Sara Cherry
  • Scott E Hensley
  • Sokratis A Apostolidis
  • Alexander C Huang
  • Laura A Vella
  • Michael R Betts
  • Nuala J Meyer
  • E John Wherry
  • Science.2020 Jul;eabc8511. doi: 10.1126/science.abc8511.Epub 2020-07-15.

膵管腺癌における(プロ)レニン受容体に対するモノクローナル抗体の抗増殖効果

Antiproliferative effects of monoclonal antibodies against (pro)renin receptor in pancreatic ductal adenocarcinoma.
  • Asadur Rahman
  • Makoto Matsuyama
  • Akio Ebihara
  • Yuki Shibayama
  • Arif Ul Hasan
  • Hironori Nakagami
  • Fumiaki Suzuki
  • Jiao Sun
  • Tomoe Kobayashi
  • Hiroki Hayashi
  • Daisuke Nakano
  • Hideki Kobara
  • Tsutomu Masaki
  • Akira Nishiyama
  • Mol. Cancer Ther..2020 Jul;molcanther.0228.2019. doi: 10.1158/1535-7163.MCT-19-0228.Epub 2020-07-15.

自己免疫CD8 T細胞の炎症性プロファイルはLDHA活性の増加と好気性解糖に依存している

Proinflammatory profile of autoimmune CD8 T cells relies on increased LDHA activity and aerobic glycolysis.
  • M Margarida Souto-Carneiro
  • Karel D Klika
  • Mónica T Abreu
  • André P Meyer
  • Rainer Saffrich
  • Roger Sandhoff
  • Richard Jennemann
  • Franziska V Kraus
  • Lars-Oliver Tykocinski
  • Volker Eckstein
  • Lina Carvalho
  • Mark Kriegsmann
  • Thomas Giese
  • Hanns-Martin Lorenz
  • Rui A Carvalho
  • 2020 Jun;doi: 10.1002/art.41420.Epub 2020-06-30.

メキシコの高齢者におけるCOVID-19の重症度および致死率に対する構造的健康決定要因および併存疾患の不平等な影響。時系列的な加齢を超えた考察

Unequal impact of structural health determinants and comorbidity on COVID-19 severity and lethality in older Mexican adults: Considerations beyond chronological aging.
  • Omar Yaxmehen Bello-Chavolla
  • Armando González-Díaz
  • Neftali Eduardo Antonio-Villa
  • Carlos A Fermín-Martínez
  • Alejandro Márquez-Salinas
  • Arsenio Vargas-Vázquez
  • Jessica Paola Bahena-López
  • Carmen García-Peña
  • Carlos A Aguilar-Salinas
  • Luis Miguel Gutiérrez-Robledo
  • J. Gerontol. A Biol. Sci. Med. Sci..2020 Jun;glaa163. doi: 10.1093/gerona/glaa163.Epub 2020-06-29.

ビフィドバクテリウム・アドレセンティスとラクトバチルス・ラムノサスは、腸内細菌叢に依存する異なる経路の調節を通じて、高脂肪・高コレステロール食によって誘導される非アルコール性脂肪性肝疾患を緩和することが示された

Bifidobacterium adolescentis and Lactobacillus rhamnosus alleviate non-alcoholic fatty liver disease induced by a high-fat, high-cholesterol diet through modulation of different gut microbiota-dependent pathways.
  • Gang Wang
  • Ting Jiao
  • Yue Xu
  • Daozheng Li
  • Qian Si
  • Jianfeng Hao
  • Jianxin Zhao
  • Hao Zhang
  • Wei Chen
  • Food Funct.2020 Jun;doi: 10.1039/c9fo02905b.Epub 2020-06-23.

吸入損傷が疑われる成人患者における自由対制限的挿管基準の予測適用可能性-レトロスペクティブ・コホート研究

The predictive applicability of liberal versus restrictive intubation criteria in adult patients with suspected inhalation injury - a retrospective cohort study.
  • Minesh Chotalia
  • Christine Pirrone
  • Thomas Mangham
  • Barbara Torlinska
  • Randeep Mullhi
  • Kaye England
  • Tomasz Torlinski
  • J Burn Care Res.2020 Jun;iraa092. doi: 10.1093/jbcr/iraa092.Epub 2020-06-06.

イメージング質量分析法は、ラットモデルにおける肝性温熱虚血と再灌流中のジヒドロキシコリン酸のタウリン抱合体の変化を明らかにします

Imaging Mass Spectrometry Reveals the Changes in the Taurine Conjugates of Dihydroxycholanoic Acid During Hepatic Warm Ischemia and Reperfusion in a Rat Model.
  • Kengo Shibata
  • Takahiro Hayasaka
  • Satsuki Hashimoto
  • Kohei Umemoto
  • Takahisa Ishikawa
  • Sodai Sakamoto
  • Koichi Kato
  • Shingo Shimada
  • Norio Kawamura
  • Kenji Wakayama
  • Nozomi Kobayashi
  • Yuka Hama
  • Moto Fukai
  • Tsuyoshi Shimamura
  • Akinobu Taketomi
  • Transplant. Proc..2020 Jun;S0041-1345(19)31739-7. doi: 10.1016/j.transproceed.2020.01.169.Epub 2020-06-30.

鳥類および魚類におけるアリール炭化水素受容体の低活性アゴニストへの曝露による早期ライフステージ死亡率の予測。種を超えた定量的副作用経路のアプローチ

Predicting Early Life Stage Mortality in Birds and Fishes from Exposure to Low Potency Agonists of the Aryl Hydrocarbon Receptor: A Cross-species Quantitative Adverse Outcome Pathway Approach.
  • Jon A Doering
  • Justin Dubiel
  • Steve Wiseman
  • Environ. Toxicol. Chem..2020 Jul;doi: 10.1002/etc.4816.Epub 2020-07-10.

インドネシアにおけるwMel Wolbachiaの規模での放流を用いたデング熱の制御の費用対効果:モデリング研究

The cost-effectiveness of controlling dengue in Indonesia using wMel Wolbachia released at scale: a modelling study.
  • Oliver J Brady
  • Dinar D Kharisma
  • Nandyan N Wilastonegoro
  • Kathleen M O'Reilly
  • Emilie Hendrickx
  • Leonardo S Bastos
  • Laith Yakob
  • Donald S Shepard
  • BMC Med.2020 Jul;18(1):186. 10.1186/s12916-020-01638-2. doi: 10.1186/s12916-020-01638-2.Epub 2020-07-09.

市中肺炎で入院した小児および成人におけるパラインフルエンザウイルス1~3型感染

Parainfluenza Virus Types 1-3 Infections Among Children and Adults Hospitalized with Community-Acquired Pneumonia.
  • Leigh M Howard
  • Kathryn M Edwards
  • Yuwei Zhu
  • Derek J Williams
  • Wesley H Self
  • Seema Jain
  • Krow Ampofo
  • Andrew T Pavia
  • Sandra R Arnold
  • Jonathan A McCullers
  • Evan J Anderson
  • Richard G Wunderink
  • Carlos G Grijalva
  • Clin. Infect. Dis..2020 Jul;ciaa973. doi: 10.1093/cid/ciaa973.Epub 2020-07-18.

幹細胞多能性遺伝子Klf4とOct4は、末期の動脈硬化性病変の発症に重要な複雑なSMC表現型の変化を制御している

The Stem Cell Pluripotency Genes Klf4 and Oct4 Regulate Complex SMC Phenotypic Changes Critical in Late-Stage Atherosclerotic Lesion Pathogenesis.
  • Gabriel F Alencar
  • Katherine M Owsiany
  • Santosh K
  • Katyayani Sukhavasi
  • Giuseppe Mocci
  • Anh Nguyen
  • Corey M Williams
  • Sohel Shamsuzzaman
  • Michal Mokry
  • Christopher A Henderson
  • Ryan Haskins
  • Richard A Baylis
  • Aloke V Finn
  • Coleen A McNamara
  • Eli R Zunder
  • Vamsidhar Venkata
  • Gerard Pasterkamp
  • Johan Björkegren
  • Stefan Bekiranov
  • Gary K Owens
  • Circulation.2020 Jul;doi: 10.1161/CIRCULATIONAHA.120.046672.Epub 2020-07-17.

トランスフェモラル大動脈弁置換術または外科的大動脈弁置換術後の大動脈弁狭窄症患者における右室機能のメタアナリシス

Meta-analysis of right ventricular function in patients with aortic stenosis after transfemoral aortic valve replacement or surgical aortic valve replacement.
  • Yunshan Cao
  • Vikas Singh
  • Aqian Wang
  • Liyan Zhang
  • Tingting He
  • Hongling Su
  • Rong Wei
  • Yichao Duan
  • Kaiyu Jiang
  • Wenyu Wu
  • Yan Huang
  • Sammy Elmariah
  • Guanming Qi
  • Xin Su
  • Yan Zhang
  • Min Zhang
  • Ther Adv Chronic Dis.2020;11:2040622320933775. 10.1177_2040622320933775. doi: 10.1177/2040622320933775.Epub 2020-07-03.

細菌性アミロイドcurliのin vivo合成は、S. Typhimurium感染時の関節炎症に寄与する

In vivo synthesis of bacterial amyloid curli contributes to joint inflammation during S. Typhimurium infection.
  • Amanda L Miller
  • J Alex Pasternak
  • Nicole J Medeiros
  • Lauren K Nicastro
  • Sarah A Tursi
  • Elizabeth G Hansen
  • Ryan Krochak
  • Akosiererem S Sokaribo
  • Keith D MacKenzie
  • Melissa B Palmer
  • Dakoda J Herman
  • Nikole L Watson
  • Yi Zhang
  • Heather L Wilson
  • R Paul Wilson
  • Aaron P White
  • Çagla Tükel
  • PLoS Pathog..2020 Jul;16(7):e1008591. PPATHOGENS-D-20-00087. doi: 10.1371/journal.ppat.1008591.Epub 2020-07-09.

化学療法誘発性末梢神経障害に対する鍼治療の有効性。A pilot, Randomized, Assessor-Blinded, Controlled Trial

Effectiveness of Acupuncture Treatment on Chemotherapy-Induced Peripheral Neuropathy: A Pilot, Randomized, Assessor-Blinded, Controlled Trial.
  • Somayeh Iravani
  • Amir Hooman Kazemi Motlagh
  • Seyede Zahra Emami Razavi
  • Farhad Shahi
  • Jing Wang
  • Li Hou
  • Wenjun Sun
  • Mohammad Reza Afshari Fard
  • Mahdi Aghili
  • Mehrdad Karimi
  • Hossein Rezaeizadeh
  • Baixiao Zhao
  • Pain Res Manag.2020;2020:2504674. doi: 10.1155/2020/2504674.Epub 2020-06-29.

大腸癌細胞におけるプログラムされた死のリガンド2(PD-L2)の発現を増加させるが、4-1BBリガンドの発現は増加させない

Increasing the expression of programmed death ligand 2 (PD-L2) but not 4-1BB ligand in colorectal cancer cells.
  • Parastoo Shakerin
  • Bijan Sedighi Moghadam
  • Kaveh Baghaei
  • Zahra Safaei Naraghi
  • Kambiz Kamyab Hesari
  • Hamid Asadzadeh Aghdaei
  • Raheleh Shokouhi Shoormasti
  • Mohammad Sadegh Fazeli
  • Maryam Nourizadeh
  • Mol. Biol. Rep..2020 Jul;10.1007/s11033-020-05289-7. doi: 10.1007/s11033-020-05289-7.Epub 2020-07-13.

口腔液中の17種類の乱用薬物の定量のための新しいLC-MS/MS確認法と実試料への適用

A new LC-MS/MS confirmation method for the determination of 17 drugs of abuse in oral fluid and its application to real samples.
  • Elisa Bassotti
  • Giuseppe Maria Merone
  • Annachiara D'Urso
  • Fabio Savini
  • Marcello Locatelli
  • Angela Tartaglia
  • Paolo Dossetto
  • Cristian D'Ovidio
  • Ugo de Grazia
  • Forensic Sci. Int..2020 Jul;312:110330. S0379-0738(20)30192-4. doi: 10.1016/j.forsciint.2020.110330.Epub 2020-05-12.

酸化ストレス、損傷と不十分な抗酸化防御が強化され、水不足ストレスと熱ストレスの組み合わせでの不十分な回復に向けて貢献している(Bathua)のいずれかのストレスだけではなく、どちらかのストレスに比べて

Enhanced oxidative stress, damage and inadequate antioxidant defense contributes towards insufficient recovery in water deficit stress and heat stress combination compared to either stresses alone in (Bathua).
  • Vimal Kumar Semwal
  • Renu Khanna-Chopra
  • Physiol Mol Biol Plants.2020 Jul;26(7):1331-1339. 821. doi: 10.1007/s12298-020-00821-2.Epub 2020-06-10.