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日本語AIでPubMedを検索

日本語AIでPubMedを検索

PubMedの提供する医学論文データベースを日本語で検索できます。AI(Deep Learning)を活用した機械翻訳エンジンにより、精度高く日本語へ翻訳された論文をご参照いただけます。

みんなが読んでいる論文

抗線溶性部位特異的ファーマコレーザー治療によるポートワインの汚れの治療のための熱感受性リポソームのインビボ評価

In Vivo Assessment of Thermosensitive Liposomes for the Treatment of Port Wine Stains by Antifibrinolytic Site-Specific Pharmaco-Laser Therapy.
  • Mingjuan Li
  • M Ingmar van Raath
  • Shervin Khakpour
  • Ahmet Seçilir
  • Bart C Sliggers
  • Xuan Huang
  • Baoyue Ding
  • Gert Storm
  • René R van der Hulst
  • Anton I P M de Kroon
  • Michal Heger
  • Pharmaceutics.2020 Jun;12(6). E591. doi: 10.3390/pharmaceutics12060591.Epub 2020-06-25.

硝酸ナトリウム処理ラットにおけるJ.carnae葉抽出物の血球保護作用および赤血球膜安定化作用

Haematoprotective and red blood cell membrane stabilizing effects of Justicia carnae leaf extracts in sodium nitrate-treated rats.
  • Eberechukwu Mbanaso
  • Azubuike Nwankwo
  • Solomon Nnah Ijioma
  • Okezie Emmanuel
  • Eziuche Amadike Ugbogu
  • Ngozi Nwagbara
  • Kingsley Ugwuanyi
  • J Basic Clin Physiol Pharmacol.2020 Jul;/j/jbcpp.ahead-of-print/jbcpp-2019-0275/jbcpp-2019-0275.xml. doi: 10.1515/jbcpp-2019-0275.Epub 2020-07-13.

ヒトコレクトリン-11(COLEC11)とそのMASP2との相乗的な遺伝的相互作用は、シャーガス病の病態生理に関連しています

Human collectin-11 (COLEC11) and its synergic genetic interaction with MASP2 are associated with the pathophysiology of Chagas Disease.
  • Thaisa Lucas Sandri
  • Fabiana Antunes Andrade
  • Kárita Cláudia Freitas Lidani
  • Elias Einig
  • Angelica Beate Winter Boldt
  • Benjamin Mordmüller
  • Meral Esen
  • Iara J Messias-Reason
  • PLoS Negl Trop Dis.2019 04;13(4):e0007324. PNTD-D-18-01714. doi: 10.1371/journal.pntd.0007324.Epub 2019-04-17.

黒胡椒由来のアルカロイドはNF-κB経路の活性化を阻害することにより、マウスマクロファージにおける抗炎症活性を示します

Alkaloids from Black Pepper ( L.) Exhibit Anti-Inflammatory Activity in Murine Macrophages by Inhibiting Activation of NF-κB Pathway.
  • Heying Pei
  • Linlin Xue
  • Minghai Tang
  • Huan Tang
  • Shuang Kuang
  • Lun Wang
  • Xu Ma
  • Xiaoying Cai
  • Yan Li
  • Min Zhao
  • Aihua Peng
  • Haoyu Ye
  • Lijuan Chen
  • J. Agric. Food Chem..2020 Feb;68(8):2406-2417. doi: 10.1021/acs.jafc.9b07754.Epub 2020-02-18.

一半球の可塑性、二半球からの制御:新生児ラットの片側皮質脊髄損傷後の下降運動経路の適応性

Plasticity in One Hemisphere, Control From Two: Adaptation in Descending Motor Pathways After Unilateral Corticospinal Injury in Neonatal Rats.
  • Tong-Chun Wen
  • Sophia Lall
  • Corey Pagnotta
  • James Markward
  • Disha Gupta
  • Shivakeshavan Ratnadurai-Giridharan
  • Jacqueline Bucci
  • Lucy Greenwald
  • Madelyn Klugman
  • N Jeremy Hill
  • Jason B Carmel
  • Front Neural Circuits.2018;12:28. doi: 10.3389/fncir.2018.00028.Epub 2018-04-12.

サフィナミドの覚醒剤誘発性神経変性に対する神経保護作用と神経生存能。BDNF/TrkB/PGC-1αシグナル伝達経路とミトコンドリアアンカップリングプロテイン-2(UCP-2)の役割の仮説的可能性

Neuroprotective and neuro-survival properties of safinamide against methamphetamine-induced neurodegeneration: Hypothetic possible role of BDNF/TrkB/PGC-1α signaling pathway and mitochondrial uncoupling protein -2(UCP-2).
  • Afrah Sepehr
  • Fereshteh Taheri
  • Sara Heidarian
  • Majid Motaghinejad
  • Sepideh Safari
  • Med. Hypotheses.2020 Jul;143:110094. S0306-9877(20)30442-4. doi: 10.1016/j.mehy.2020.110094.Epub 2020-07-11.

甲状腺転写因子1(TTF-1)陰性、EGFR/ALK陰性の肺腺がんにおけるペメトレキセドベースの化学療法は、ペメトレキセドを含まないレジメンよりも劣る:傾向スコアマッチドペア分析

Pemetrexed-Based Chemotherapy Is Inferior to Pemetrexed-Free Regimens in Thyroid Transcription Factor 1 (TTF-1)-Negative, EGFR/ALK-Negative Lung Adenocarcinoma: A Propensity Score Matched Pairs Analysis.
  • Nikolaj Frost
  • Tamar Zhamurashvili
  • Maximilian von Laffert
  • Frederick Klauschen
  • Christoph Ruwwe-Glösenkamp
  • Matthias Raspe
  • Matthias Brunn
  • Sebastian Ochsenreither
  • Bettina Temmesfeld-Wollbrück
  • Norbert Suttorp
  • Christian Grohé
  • Martin Witzenrath
  • Clin Lung Cancer.2020 May;S1525-7304(20)30154-6. doi: 10.1016/j.cllc.2020.05.014.Epub 2020-05-22.

ミクログリアの活性化を調節することで、歯状回におけるアルギナーゼ1を介した母体免疫活性化による統合失調症関連行動の表現型を防ぐことができる

Modulating microglia activation prevents maternal immune activation induced schizophrenia-relevant behavior phenotypes via arginase 1 in the dentate gyrus.
  • Yucen Xia
  • Zhiqing Zhang
  • Weipeng Lin
  • Jinglan Yan
  • Chuan'an Zhu
  • Dongmin Yin
  • Su He
  • Yang Su
  • Nenggui Xu
  • Robert William Caldwell
  • Lin Yao
  • Yongjun Chen
  • Neuropsychopharmacology.2020 Jun;10.1038/s41386-020-0743-7. doi: 10.1038/s41386-020-0743-7.Epub 2020-06-29.

インド・ベンガルールの農村と都市の界面における野縁植生の構造と構成:農業生態系の未踏の側面に関する事例研究

Structure and composition of field margin vegetation in the rural-urban interface of Bengaluru, India: a case study on an unexplored dimension of agroecosystems.
  • Sunil Nautiyal
  • Mrinalini Goswami
  • Rama Rao Nidamanuri
  • Ellen M Hoffmann
  • Andreas Buerkert
  • Environ Monit Assess.2020 Jul;192(8):520. 10.1007/s10661-020-08428-6. doi: 10.1007/s10661-020-08428-6.Epub 2020-07-15.

人工河川の底生無脊椎動物および生態系機能に及ぼす有機UVフィルター3-(4-メチルベンジリデン)樟脳の効果(英文

Effects of the organic UV-filter, 3-(4-methylbenzylidene) camphor, on benthic invertebrates and ecosystem function in artificial streams.
  • Diana Campos
  • Ana L Machado
  • Diogo N Cardoso
  • Ana Rita R Silva
  • Patrícia V Silva
  • Andreia C M Rodrigues
  • Fátima C P Simão
  • Susana Loureiro
  • Kateřina Grabicová
  • Petra Nováková
  • Amadeu M V M Soares
  • João L T Pestana
  • Environ. Pollut..2020 May;260:113981. S0269-7491(19)36601-1. doi: 10.1016/j.envpol.2020.113981.Epub 2020-01-13.

肥満成人のスリーブ胃切除術後1年後の完全寛解および部分寛解、改善、または糖尿病状態の変化なしと関連する因子

Factors associated with complete and partial remission, improvement, or unchanged diabetes status of obese adults 1 year after sleeve gastrectomy.
  • Isra Elgenaied
  • Walid El Ansari
  • Mohamed Aly Elsherif
  • Sama Abdulrazzaq
  • Amjad Salah Qabbani
  • Wahiba Elhag
  • Surg Obes Relat Dis.2020 May;S1550-7289(20)30271-9. doi: 10.1016/j.soard.2020.05.013.Epub 2020-05-27.

Dioscorea tokoro Makino ex Miyabe に含まれるトコロニンは、古典的 MAPK パスウェイ活性化の抑制を介して B16 細胞のα-MSH 誘導メラニン生成を抑制した

Tokoronin Contained in Dioscorea tokoro Makino ex Miyabe Suppressed α-MSH-Induced Melanogenesis in B16 Cells via Suppression of Classical MAPK Pathway Activation.
  • Motohiko Ukiya
  • Daisuke Sato
  • Hirokazu Kimura
  • Yasuaki Hirai
  • Atsuyoshi Nishina
  • Chem. Biodivers..2020 Jun;17(6):e2000077. doi: 10.1002/cbdv.202000077.Epub 2020-05-07.

TBK1 と IKKε は、ミエロイド細胞における STING 誘導 NF-κB 応答を媒介するために冗長に作用します

TBK1 and IKKε Act Redundantly to Mediate STING-Induced NF-κB Responses in Myeloid Cells.
  • Katherine R Balka
  • Cynthia Louis
  • Tahnee L Saunders
  • Amber M Smith
  • Dale J Calleja
  • Damian B D'Silva
  • Fiona Moghaddas
  • Maximilien Tailler
  • Kate E Lawlor
  • Yifan Zhan
  • Christopher J Burns
  • Ian P Wicks
  • Jonathan J Miner
  • Benjamin T Kile
  • Seth L Masters
  • Dominic De Nardo
  • Cell Rep.2020 Apr;31(1):107492. S2211-1247(20)30370-3. doi: 10.1016/j.celrep.2020.03.056.

片頭痛患者の甲状腺機能に関連するホルモンレベルを報告した最近の研究のシステマティックレビューおよびメタアナリシスを、2020年4月までに実施した

A systematic review and meta-analysis of recent studies reporting hormone levels related to thyroid gland function in migraineurs, until April 2020.
  • Ali Seidkhani-Nahal
  • Asad Mirzaei
  • Gholam Basati
  • Davoud Parvizi-Faraz
  • Ali Noori-Zadeh
  • Hormones (Athens).2020 Jul;10.1007/s42000-020-00228-4. doi: 10.1007/s42000-020-00228-4.Epub 2020-07-15.

グルタミン制限下で選択されたチャイニーズハムスター卵巣細胞における過剰なグルタミン合成酵素活性は、グルタミン不足条件下では成長制限的であり、セリンによって阻害される可能性がある

Superfluous glutamine synthetase activity in Chinese Hamster Ovary cells selected under glutamine limitation is growth limiting in glutamine-replete conditions and can be inhibited by serine.
  • Vishwanathgouda Maralingannavar
  • Dharmeshkumar Parmar
  • Venkateswarlu Panchagnula
  • Mugdha Gadgil
  • Biotechnol. Prog..2019 09;35(5):e2856. doi: 10.1002/btpr.2856.Epub 2019-06-12.

ヒト臍帯多能性間葉系間葉系間葉系間質細胞は、炎症反応や酸化ストレスを軽減することで、精子形成細胞の急性虚血再灌流障害を緩和することがわかった

Human umbilical cord multipotent mesenchymal stromal cells alleviate acute ischemia-reperfusion injury of spermatogenic cells via reducing inflammatory response and oxidative stress.
  • Liang Zhong
  • Mengbo Yang
  • Xiangyu Zou
  • Tao Du
  • Huiming Xu
  • Jie Sun
  • Stem Cell Res Ther.2020 Jul;11(1):294. 10.1186/s13287-020-01813-5. doi: 10.1186/s13287-020-01813-5.Epub 2020-07-17.

転移性大腸がん患者の予後評価のための無細胞全DNA、カルチノエンブリオニック抗原、C反応性タンパク質

Total cell-free DNA, carcinoembryonic antigen, and C-reactive protein for assessment of prognosis in patients with metastatic colorectal cancer.
  • Karen-Lise Garm Spindler
  • Christina Demuth
  • Boe Sandahl Sorensen
  • Julia S Johansen
  • Dorte Nielsen
  • Niels Pallisgaard
  • Estrid Hoegdall
  • Per Pfeiffer
  • Benny Vittrup Jensen
  • Tumour Biol..2018 Nov;40(11):1010428318811207. doi: 10.1177/1010428318811207.

高プロラクチン血症は、橋本甲状腺炎患者の甲状腺自己免疫に対するビタミンD/セレノメチオニン併用療法の抑制効果を減少させる。試験的研究

Hyperprolactinaemia attenuates the inhibitory effect of vitamin D/selenomethionine combination therapy on thyroid autoimmunity in euthyroid women with Hashimoto's thyroiditis: A pilot study.
  • Robert Krysiak
  • Karolina Kowalcze
  • Bogusław Okopień
  • J Clin Pharm Ther.2020 Jul;doi: 10.1111/jcpt.13214.Epub 2020-07-10.

動的光による光合成の抑制は、窒素欠乏条件下では、十分な窒素供給条件下よりも、ダイズの方がより少なく、むしろ多くなった

Dynamic light caused less photosynthetic suppression, rather than more, under nitrogen deficit conditions than under sufficient nitrogen supply conditions in soybean.
  • Yu-Ting Li
  • Ying Li
  • Yue-Nan Li
  • Ying Liang
  • Qiang Sun
  • Geng Li
  • Peng Liu
  • Zi-Shan Zhang
  • Hui-Yuan Gao
  • BMC Plant Biol..2020 Jul;20(1):339. 10.1186/s12870-020-02516-y. doi: 10.1186/s12870-020-02516-y.Epub 2020-07-17.

冠動脈CT造影における低ヨード濃度造影を用いた低管電圧プロトコルと高管電圧プロトコルを用いた高ヨード濃度造影の実現可能性を比較した

Comparing feasibility of low-tube-voltage protocol with low-iodine-concentration contrast and high-tube-voltage protocol with high-iodine-concentration contrast in coronary computed tomography angiography.
  • Min Jae Cha
  • Sung Mok Kim
  • Tae Ran Ahn
  • Yeon Hyeon Choe
  • PLoS ONE.2020;15(7):e0236108. PONE-D-20-04325. doi: 10.1371/journal.pone.0236108.Epub 2020-07-16.

PRRSV-1の病原菌Lena株感染の急性期における肺組織傷害におけるプロおよび抗炎症反応の活性化

Activation of pro- and anti-inflammatory responses in lung tissue injury during the acute phase of PRRSV-1 infection with the virulent strain Lena.
  • J M Sánchez-Carvajal
  • I M Rodríguez-Gómez
  • I Ruedas-Torres
  • F Larenas-Muñoz
  • I Díaz
  • C Revilla
  • E Mateu
  • J Domínguez
  • G Martín-Valls
  • I Barranco
  • F J Pallarés
  • L Carrasco
  • J Gómez-Laguna
  • Vet. Microbiol..2020 Jul;246:108744. S0378-1135(20)30433-8. doi: 10.1016/j.vetmic.2020.108744.Epub 2020-06-02.

HMGB1の酸性尾部は、その二次構造とコンフォメーションの柔軟性を制御している。円形二色性と分子動力学シミュレーションによる研究

The acidic tail of HMGB1 regulates its secondary structure and conformational flexibility: A circular dichroism and molecular dynamics simulation study.
  • Wresti L Anggayasti
  • Kenta Ogino
  • Eiji Yamamoto
  • Erik Helmerhorst
  • Kenji Yasuoka
  • Ricardo L Mancera
  • Comput Struct Biotechnol J.2020;18:1160-1172. S2001-0370(20)30275-0. doi: 10.1016/j.csbj.2020.05.012.Epub 2020-05-16.

Toll-like receptor 7-adapter complexはHIV刺激を受けた形質細胞性樹状細胞におけるインターフェロン-α産生を調節している

Toll-like receptor 7-adapter complex modulates interferon-α production in HIV-stimulated plasmacytoid dendritic cells.
  • Andy A Patamawenu
  • Nathaniel E Wright
  • Tulley Shofner
  • Sean Evans
  • Maura M Manion
  • Nicole Doria-Rose
  • Stephen A Migueles
  • Daniel Mendoza
  • Bennett Peterson
  • Christopher Wilhelm
  • Julia Rood
  • Amy Berkley
  • Nancy A Cogliano
  • C Jason Liang
  • Kiki Tesselaar
  • Frank Miedema
  • Julian Bess
  • Jeffrey Lifson
  • Mark Connors
  • PLoS ONE.2019;14(12):e0225806. PONE-D-19-21147. doi: 10.1371/journal.pone.0225806.Epub 2019-12-12.

未分割ヘパリンはホスファチジルイノシトール-3キナーゼ/セリン/スレオニンキナーゼ/核因子κ-B経路を介して内皮バリア機能障害を減衰させる

Unfractionated heparin attenuates endothelial barrier dysfunction via the phosphatidylinositol-3 kinase/serine/threonine kinase/nuclear factor kappa-B pathway.
  • Sheng-Tian Mu
  • Jie Tang
  • Jian-Qi Ma
  • Yu Zhong
  • Han-Zhe Liu
  • Xiao-Chun Ma
  • Zhen Zheng
  • Chin. Med. J..2020 Jul;doi: 10.1097/CM9.0000000000000905.Epub 2020-07-01.

パリ郊外の大学病院における COVID-19 を示唆する症状を持つ医療従事者の間での SARS-CoV-2 の鼻咽頭感染

[Nasopharyngeal carriage of SARS-CoV-2 among health personnel with symptoms suggestive of COVID-19 in a University Hospital in the Paris suburbs].
  • S Greffe
  • F Espinasse
  • C Duran
  • S Labrune
  • M Sirol
  • B Mantalvan
  • M C Gramer
  • C Babulle
  • G Do Rosario
  • Q Vauvillier
  • A Huet
  • A Van der Heidjen
  • J Tysebaert
  • L F Kramarz
  • J-P Rabes
  • G Pellissier
  • T Chinet
  • F Moreau
  • E Rouveix
  • Rev Med Interne.2020 Jul;S0248-8663(20)30243-5. doi: 10.1016/j.revmed.2020.06.017.Epub 2020-07-08.

COVID-19がブラジルの泌尿器科医の臨床実践、収入、健康、生活行動に与えた影響

Impact of COVID-19 on clinical practice, income, health and lifestyle behavior of Brazilian urologists.
  • Cristiano M Gomes
  • Luciano A Favorito
  • João Victor T Henriques
  • Alfredo F Canalini
  • Karin M J Anzolch
  • Roni de Carvalho Fernandes
  • Carlos H S Bellucci
  • Caroline S Silva
  • Marcelo L Wroclawski
  • Antonio Carlos L Pompeo
  • José de Bessa
  • Int Braz J Urol.2020 Jun;46. IBJU20209915. doi: 10.1590/S1677-5538.IBJU.2020.99.15.Epub 2020-06-05.

新規タンパク質恒常性モジュレーターBTX306は骨髄腫で活性を示し、ボルテゾミブとレナリドミドマイドの耐性を克服している

The novel protein homeostatic modulator BTX306 is active in myeloma and overcomes bortezomib and lenalidomide resistance.
  • Jianxuan Zou
  • Richard J Jones
  • Hua Wang
  • Isere Kuiatse
  • Fazal Shirazi
  • Elisabet E Manasanch
  • Hans C Lee
  • Robert Sullivan
  • Leah Fung
  • Normand Richard
  • Paul Erdman
  • Eduardo Torres
  • David Hecht
  • Imelda Lam
  • Brooke McElwee
  • Aparajita H Chourasia
  • Kyle W H Chan
  • Frank Mercurio
  • David I Stirling
  • Robert Z Orlowski
  • J. Mol. Med..2020 Jul;10.1007/s00109-020-01943-6. doi: 10.1007/s00109-020-01943-6.Epub 2020-07-06.

介護施設の入所者および職員における SARS-CoV-2 の無症状感染。リアルタイムPCRおよび血清学的検査の結果

Presymptomatic Transmission of SARS-CoV-2 Amongst Residents and Staff at a Skilled Nursing Facility: Results of Real-Time PCR and Serologic Testing.
  • Scott A Goldberg
  • Jochen Lennerz
  • Michael Klompas
  • Eden Mark
  • Virginia M Pierce
  • Ryan W Thompson
  • Charles T Pu
  • Lauren L Ritterhouse
  • Anand Dighe
  • Eric S Rosenberg
  • David C Grabowski
  • Clin. Infect. Dis..2020 Jul;ciaa991. doi: 10.1093/cid/ciaa991.Epub 2020-07-15.

犬モデルにおける内側コンパートメント性関節症の治療に骨軟骨移植とメニスカル移植が有効であることを明らかにしました

Unicompartmental Bipolar Osteochondral and Meniscal Allograft Transplantation is Effective for Treatment of Medial Compartment Gonarthrosis in a Canine Model.
  • Anna J Schreiner
  • James P Stannard
  • Aaron M Stoker
  • Chantelle C Bozynski
  • Keiichi Kuroki
  • Cristi R Cook
  • James L Cook
  • J. Orthop. Res..2020 Jul;doi: 10.1002/jor.24801.Epub 2020-07-16.

ブラジル南東部のシュガーローフ・ランド:低地のインセルバーグ植物の多様性の熱帯のホットスポット

Sugarloaf Land in south-eastern Brazil: a tropical hotspot of lowland inselberg plant diversity.
  • Luiza F A de Paula
  • Luísa O Azevedo
  • Luana Paula Mauad
  • Leandro Jorge Telles Cardoso
  • João Marcelo Alvarenga Braga
  • Ludovic J C Kollmann
  • Claudio N Fraga
  • Luiz Menini Neto
  • Paulo H Labiak
  • Renato Mello-Silva
  • Stefan Porembski
  • Rafaela Campostrini Forzza
  • Biodivers Data J.2020;8:e53135. 53135. doi: 10.3897/BDJ.8.e53135.Epub 2020-06-19.

COVID-19時代の外科的がん診療:最前線の見解とコンセンサス.

Surgical cancer care in the COVID-19 era: front line views and consensus.
  • Rodrigo Nascimento Pinheiro
  • Felipe J F Coimbra
  • Wilson Luiz DA Costa-Jr
  • Heber Salvador DE Castro Ribeiro
  • Reitan Ribeiro
  • Alberto Julius Alves Wainstein
  • Gustavo Andreazza Laporte
  • Manoel Jesus Pinheiro Coelho-Jr
  • Paulo Henrique DE Sousa Fernandes
  • Eduardo Zanella Cordeiro
  • Bruno JosÉ Queiroz Sarmento
  • Marco Antonio C Guimaraes-Filho
  • Marciano Anghinoni
  • Glauco Baiocchi
  • Alexandre Ferreira Oliveira
  • Rev Col Bras Cir.2020;47:e20202601. S0100-69912020000100181. doi: 10.1590/0100-6991e-20202601.Epub 2020-07-03.

パーム油工場排水から分離された細菌株を用いたバイオ凝集剤の製造方法とその水からのエリオクロームブラックT色素の除去への応用

Bioflocculants Produced by Bacterial Strains Isolated from Palm Oil Mill Effluent for Application in the Removal of Eriochrome Black T Dye from Water.
  • Syed Zaghum Abbas
  • Yang-Chun Yong
  • Moonis Ali Khan
  • Masoom Raza Siddiqui
  • Afnan Ali Hussain Hakami
  • Shareefa Ahmed Alshareef
  • Marta Otero
  • Mohd Rafatullah
  • Polymers (Basel).2020 Jul;12(7). E1545. doi: 10.3390/polym12071545.Epub 2020-07-13.

左心低形成症候群に関連した頭部ドメイン変異を有する誘導多能性幹細胞心筋細胞の収縮性

Contractility of Induced Pluripotent Stem Cell-Cardiomyocytes With an Head Domain Variant Associated With Hypoplastic Left Heart Syndrome.
  • Min-Su Kim
  • Brandon Fleres
  • Jerrell Lovett
  • Melissa Anfinson
  • Sai Suma K Samudrala
  • Lauren J Kelly
  • Laura E Teigen
  • Matthew Cavanaugh
  • Maribel Marquez
  • Aron M Geurts
  • John W Lough
  • Michael E Mitchell
  • Robert H Fitts
  • Aoy Tomita-Mitchell
  • Front Cell Dev Biol.2020;8:440. doi: 10.3389/fcell.2020.00440.Epub 2020-06-23.

ペリリルアルコールとクエルセチンは、PARP1を介したmiR-204のダウンレギュレーションとそのダウンストリーム経路を介して、ラットのモノクロタリン誘発性肺動脈高血圧を改善した

Perillyle alcohol and Quercetin ameliorate monocrotaline-induced pulmonary artery hypertension in rats through PARP1-mediated miR-204 down-regulation and its downstream pathway.
  • Soodeh Rajabi
  • Hamid Najafipour
  • Saeideh Jafarinejad Farsangi
  • Siyavash Joukar
  • Ahmad Beik
  • Maryam Iranpour
  • Zeinab Kordestani
  • BMC Complement Med Ther.2020 Jul;20(1):218. 10.1186/s12906-020-03015-1. doi: 10.1186/s12906-020-03015-1.Epub 2020-07-13.

アルストローム症候群患者におけるPBI-4050による治療:第2相、単施設、単群、非盲検試験の試験プロトコール

Treatment with PBI-4050 in patients with Alström syndrome: study protocol for a phase 2, single-Centre, single-arm, open-label trial.
  • Shanat Baig
  • Vishy Veeranna
  • Shaun Bolton
  • Nicola Edwards
  • Jeremy W Tomlinson
  • Konstantinos Manolopoulos
  • John Moran
  • Richard P Steeds
  • Tarekegn Geberhiwot
  • BMC Endocr Disord.2018 Nov;18(1):88. 10.1186/s12902-018-0315-6. doi: 10.1186/s12902-018-0315-6.Epub 2018-11-26.

健康なボランティアの血清サイトカイン濃度に対するプロポフォールとデクスメデトミジンの効果(レミフェンタニルの有無にかかわらず):ポストホック分析

Effects of propofol and dexmedetomidine with and without remifentanil on serum cytokine concentrations in healthy volunteers: a post hoc analysis.
  • Dirk J Bosch
  • Matijs V Meurs
  • Rianne M Jongman
  • Peter Heeringa
  • Wayel H Abdulahad
  • Michel M R F Struys
  • Br J Anaesth.2020 Jul;S0007-0912(20)30421-9. doi: 10.1016/j.bja.2020.05.039.Epub 2020-07-10.

デクスメデトミジンは、カンナビノイド受容体2のアップレギュレーションにより、腸虚血/再灌流により誘発される肺障害を改善し、その後、ホスファチジルイノシトール3-キナーゼ/Akt経路の活性化を促進します

Dexmedetomidine Ameliorates Lung Injury Induced by Intestinal Ischemia/Reperfusion by Upregulating Cannabinoid Receptor 2, Followed by the Activation of the Phosphatidylinositol 3-Kinase/Akt Pathway.
  • Meng Chen
  • Xue-Tao Yan
  • Li Ye
  • Jun-Jiao Tang
  • Zong-Ze Zhang
  • Xiang-Hu He
  • Oxid Med Cell Longev.2020;2020:6120194. doi: 10.1155/2020/6120194.Epub 2020-06-21.

先天性内側直腸低形成症による大角度外反症の治療のための最小侵襲性垂直筋移植術:症例報告と文献レビュー

Minimal invasive vertical muscle transposition for the treatment of large angle exotropia due to congenital medial rectus hypoplasia: Case Report and Literature Review.
  • Mohammad Yaser Kiarudi
  • Aliakbar Sabermoghadam
  • Mahsa Sardabi
  • Seyed Vahid Jafarzadeh
  • Mohammad Etezad Razavi
  • Strabismus.2020 Jul;:1-5. doi: 10.1080/09273972.2020.1779320.Epub 2020-07-02.

ニューヨーク市の小児病院におけるコロナウイルス疾患 2019(COVID-19)患者の疫学、臨床的特徴、および疾患の重症度

Epidemiology, Clinical Features, and Disease Severity in Patients With Coronavirus Disease 2019 (COVID-19) in a Children's Hospital in New York City, New York.
  • Philip Zachariah
  • Candace L Johnson
  • Katia C Halabi
  • Danielle Ahn
  • Anita I Sen
  • Avital Fischer
  • Sumeet L Banker
  • Mirna Giordano
  • Christina S Manice
  • Rebekah Diamond
  • Taylor B Sewell
  • Adam J Schweickert
  • John R Babineau
  • R Colin Carter
  • Daniel B Fenster
  • Jordan S Orange
  • Teresa A McCann
  • Steven G Kernie
  • Lisa Saiman
  • JAMA Pediatr.2020 06;:e202430. 2766920. doi: 10.1001/jamapediatrics.2020.2430.Epub 2020-06-03.

FIGO分類2018。化学放射線治療を受けた局所進行子宮頸がん患者を対象とした検証試験

FIGO classification 2018: Validation study in patients with locally advanced cervix cancer treated with chemo-radiation.
  • Atul Raut
  • Supriya Chopra
  • Prachi Mittal
  • Gayatri Patil
  • Umesh Mahantshetty
  • Lavanya Gurram
  • Jamema Swamidas
  • Jaya Ghosh
  • Seema Gulia
  • Palak Popat
  • Kedar Deodhar
  • Amita Maheshwari
  • Sudeep Gupta
  • Int. J. Radiat. Oncol. Biol. Phys..2020 Jul;S0360-3016(20)31418-8. doi: 10.1016/j.ijrobp.2020.07.020.Epub 2020-07-15.

遺伝性血栓症または既往のVTEを持つ女性に特に焦点を当てた妊娠中および周産期における静脈血栓塞栓症の予防-血栓症・止血学会(GTH)の女性の健康に関するワーキンググループの論文

Prevention of Venous Thromboembolism during Pregnancy and the Puerperium with a Special Focus on Women with Hereditary Thrombophilia or Prior VTE-Position Paper of the Working Group in Women's Health of the Society of Thrombosis and Haemostasis (GTH).
  • Christina Hart
  • Rupert Bauersachs
  • Ute Scholz
  • Rainer Zotz
  • Frauke Bergmann
  • Hannelore Rott
  • Birgit Linnemann
  • Hamostaseologie.2020 Jun;doi: 10.1055/a-1132-0750.Epub 2020-06-26.

誘導組織再生および誘導骨再生における成長因子を豊富に含む血漿(PRGF)の使用。ヒトにおける組織学的、免疫組織化学的、組織形態学的、放射線学的、臨床的結果のレビュー

The use of plasma rich in growth factors (PRGF) in guided tissue regeneration and guided bone regeneration. A review of histological, immunohistochemical, histomorphometrical, radiological and clinical results in humans.
  • Önder Solakoglu
  • Guido Heydecke
  • Niusha Amiri
  • Eduardo Anitua
  • Ann. Anat..2020 May;231:151528. S0940-9602(20)30072-8. doi: 10.1016/j.aanat.2020.151528.Epub 2020-05-04.

COVID-19パンデミックがプライマリーケアの中核的機能に及ぼす影響:治療は病気よりも悪化するのか?フランドル地方の開業医を対象とした質的インタビュー研究

Impact of the COVID-19 pandemic on the core functions of primary care: will the cure be worse than the disease? A qualitative interview study in Flemish GPs.
  • Veronique Verhoeven
  • Giannoula Tsakitzidis
  • Hilde Philips
  • Paul Van Royen
  • BMJ Open.2020 06;10(6):e039674. bmjopen-2020-039674. doi: 10.1136/bmjopen-2020-039674.Epub 2020-06-17.

インダカテロール/グリコピロニウム・チオトロピウムを用いた COPD 患者の 3 分間の等速シャトル試験中の労作性呼吸困難の緩和:RED 試験

Relieving exertional dyspnea during the 3-min constant speed shuttle test in patients with COPD with indacaterol/glycopyrronium tiotropium: the RED trial.
  • Jessie Beaulieu
  • Dennis Jensen
  • Denis E O'Donnell
  • Cynthia Brouillard
  • Lauren Tracey
  • Sandra Vincent
  • Éric Nadreau
  • Emmanuelle Bernard
  • Sarah Bernard
  • François Maltais
  • Ther Adv Respir Dis.2020 Jan-Dec;14:1753466620939507. doi: 10.1177/1753466620939507.

インドにおけるコロナウイルス感染症19(COVID-19)患者における胸部コンピュータ断層撮影(CT)所見のスペクトル

Spectrum of chest computed tomographic (CT) findings in coronavirus disease-19 (COVID-19) patients in India.
  • Arshed Hussain Parry
  • Abdul Haseeb Wani
  • Mudasira Yaseen
  • Khurshid Ahmad Dar
  • Naseer Ahmad Choh
  • Naseer Ahmad Khan
  • Naveed Nazir Shah
  • Majid Jehangir
  • Eur J Radiol.2020 Aug;129:109147. S0720-048X(20)30336-3. doi: 10.1016/j.ejrad.2020.109147.Epub 2020-06-24.

ミツバチプロポリスの有効成分であるカフェイン酸フェネチルエステルの抗異化作用が卵巣摘出マウスの骨量減少に及ぼす影響:マイクロコンピュータ断層撮影法による研究と組織学的解析

Anti-catabolic effect of caffeic acid phenethyl ester, an active component of honeybee propolis on bone loss in ovariectomized mice: a micro-computed tomography study and histological analysis.
  • Wangping Duan
  • Qing Wang
  • Fang Li
  • Chuan Xiang
  • Lin Zhou
  • Jiake Xu
  • Haotian Feng
  • Xiaochun Wei
  • Chin. Med. J..2014;127(22):3932-6.

レジストリデータへの機械学習の応用。小児頭蓋顔面周術期登録データセットを用いた頭蓋顔面手術中の輸血必要量の患者別予測モデルの開発

Machine Learning Applied to Registry Data: Development of a Patient-Specific Prediction Model for Blood Transfusion Requirements During Craniofacial Surgery Using the Pediatric Craniofacial Perioperative Registry Dataset.
  • Ali Jalali
  • Hannah Lonsdale
  • Lillian V Zamora
  • Luis Ahumada
  • Anh Thy H Nguyen
  • Mohamed Rehman
  • James Fackler
  • Paul A Stricker
  • Allison M Fernandez
  • Anesth. Analg..2020 06;doi: 10.1213/ANE.0000000000004988.Epub 2020-06-30.

PD-1遮断薬に対する遺伝的抵抗性メカニズムの克服

Overcoming genetically-based resistance mechanisms to PD-1 blockade.
  • Davis Y Torrejon
  • Gabriel Abril-Rodriguez
  • Ameya S Champhekar
  • Jennifer Tsoi
  • Katie M Campbell
  • Anusha Kalbasi
  • Giulia Parisi
  • Jesse M Zaretsky
  • Angel Garcia-Diaz
  • Cristina Puig-Saus
  • Gardenia Cheung-Lau
  • Thomas Wohlwender
  • Paige Krystofinski
  • Agustin Vega-Crespo
  • Christopher M Lee
  • Pau Mascaro
  • Catherine S Grasso
  • Beata Berent-Maoz
  • Begona Comin-Anduix
  • Siwen Hu-Lieskovan
  • Antoni Ribas
  • Cancer Discov.2020 May;CD-19-1409. doi: 10.1158/2159-8290.CD-19-1409.Epub 2020-05-28.

ボルテゾミブ維持療法を標準治療として行うことで、骨髄腫と診断されたばかりの患者さんに良好な結果が得られます。多施設での実際の研究

Bortezomib Maintenance Therapy as a Standard of Care Provides Favorable Outcomes in Newly Diagnosed Myeloma Patients: A Multisite Real-Life Study.
  • Efrat Luttwak
  • Moshe E Gatt
  • Eyal Lebel
  • Noa Lavi
  • Tamar Tadmor
  • Kreiniz Natalia
  • Noam Benyamini
  • Netanel Horowitz
  • Mika Geva
  • Celia Suriu
  • Irit Avivi
  • Svetlana Trestman
  • Moshe Mittelman
  • Ory Rouvio
  • Yael C Cohen
  • Clin Lymphoma Myeloma Leuk.2020 Jun;S2152-2650(20)30285-8. doi: 10.1016/j.clml.2020.06.002.Epub 2020-06-11.

ナトリウム-水素交換体-1(NHE-1)の阻害剤であるアミロリドは、虚血後の亜鉛蓄積を減少させ、海馬の神経細胞死を抑制した

An Inhibitor of the Sodium-Hydrogen Exchanger-1 (NHE-1), Amiloride, Reduced Zinc Accumulation and Hippocampal Neuronal Death after Ischemia.
  • Beom Seok Kang
  • Bo Young Choi
  • A Ra Kho
  • Song Hee Lee
  • Dae Ki Hong
  • Jeong Hyun Jeong
  • Dong Hyeon Kang
  • Min Kyu Park
  • Sang Won Suh
  • Int J Mol Sci.2020 Jun;21(12). E4232. doi: 10.3390/ijms21124232.Epub 2020-06-14.

規則(EC)No1829/2003(出願EFSA-GMO-NL-2016-135)に基づく、食品および飼料用途のための遺伝子組換え大豆MON 87708×MON 89788×A5547-127の評価

Assessment of genetically modified soybean MON 87708 × MON 89788 × A5547-127, for food and feed uses, under Regulation (EC) No 1829/2003 (application EFSA-GMO-NL-2016-135).
  • Hanspeter Naegeli
  • Jean-Louis Bresson
  • Tamas Dalmay
  • Ian Crawford Dewhurst
  • Michele Epstein
  • Leslie George Firbank
  • Philippe Guerche
  • Jan Hejatko
  • Francisco Javier Moreno
  • Ewen Mullins
  • Fabien Nogué
  • Nils Rostoks
  • Jose Juan Sánchez Serrano
  • Giovanni Savoini
  • Eve Veromann
  • Fabio Veronesi
  • Fernando Álvarez
  • Antonio Fernandez Dumont
  • Nikoletta Papadopoulou
  • Michele Ardizzone
  • Yann Devos
  • Andrea Gennaro
  • Jose Ángel Ruiz Gómez
  • Anna Lanzoni
  • Franco Maria Neri
  • Konstantinos Paraskevopoulos
  • Tommaso Raffaello
  • Giacomo De Sanctis
  • EFSA J.2019 Jul;17(7):e05733. EFS25733. doi: 10.2903/j.efsa.2019.5733.Epub 2019-07-05.