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日本語AIでPubMedを検索

日本語AIでPubMedを検索

PubMedの提供する医学論文データベースを日本語で検索できます。AI(Deep Learning)を活用した機械翻訳エンジンにより、精度高く日本語へ翻訳された論文をご参照いただけます。

みんなが読んでいる論文

高リスク進行胃癌に対するネオアジュバント化学療法+手術:KDOG1001試験の長期成績

Neoadjuvant chemotherapy plus surgery for high-risk advanced gastric cancer: long-term results of KDOG1001 trial.
  • Kei Hosoda
  • Chikatoshi Katada
  • Kenji Ishido
  • Masahiro Niihara
  • Hideki Ushiku
  • Mikiko Sakuraya
  • Marie Washio
  • Takuya Wada
  • Akinori Watanabe
  • Hiroki Harada
  • Takeo Sato
  • Hiroshi Tajima
  • Takashi Kaizu
  • Yoshimasa Kosaka
  • Hiroshi Kato
  • Norihiko Sengoku
  • Kiyoshi Tanaka
  • Takeshi Naito
  • Yusuke Kumamoto
  • Takafumi Sangai
  • Satoshi Tanabe
  • Wasaburo Koizumi
  • Keishi Yamashita
  • Naoki Hiki
  • Langenbecks Arch Surg.2020 Jul;10.1007/s00423-020-01924-w. doi: 10.1007/s00423-020-01924-w.Epub 2020-07-02.

コンゴ民主共和国の小児の対になった血液サンプルと便サンプルから分離された非伝染性サルモネラの間に高い遺伝的類似性が認められた

High genetic similarity between non-typhoidal Salmonella isolated from paired blood and stool samples of children in the Democratic Republic of the Congo.
  • Marie-France Phoba
  • Barbara Barbé
  • Benedikt Ley
  • Sandra Van Puyvelde
  • Annelies Post
  • Wesley Mattheus
  • Stijn Deborggraeve
  • Octavie Lunguya
  • Jan Jacobs
  • PLoS Negl Trop Dis.2020 Jul;14(7):e0008377. PNTD-D-20-00088. doi: 10.1371/journal.pntd.0008377.Epub 2020-07-02.

一次および再置換術の膝関節形成術の予測量は、今後30年の間に将来のヘルスケアシステムに計り知れない負担をかけることになります

The projected volume of primary and revision total knee arthroplasty will place an immense burden on future heath care systems over the next 30 years.
  • Alexander Klug
  • Yves Gramlich
  • Maximilian Rudert
  • Philipp Drees
  • Reinhard Hoffmann
  • Manuel Weißenberger
  • Karl Philipp Kutzner
  • Knee Surg Sports Traumatol Arthrosc.2020 Jul;10.1007/s00167-020-06154-7. doi: 10.1007/s00167-020-06154-7.Epub 2020-07-15.

小児患者における化学療法または放射線療法後の二次性腎新生物

Secondary Renal Neoplasia Following Chemotherapy or Radiation in Pediatric Patients.
  • Sounak Gupta
  • Chad M Vanderbilt
  • Bradley C Leibovich
  • Loren Herrera-Hernandez
  • Aditya Raghunathan
  • William R Sukov
  • Jesse S Voss
  • Emily G Barr Fritcher
  • Katelyn A Reed
  • Christine M Lohse
  • Victor E Reuter
  • Rafael E Jimenez
  • R Houston Thompson
  • John C Cheville
  • Hum. Pathol..2020 Jul;S0046-8177(20)30137-4. doi: 10.1016/j.humpath.2020.07.014.Epub 2020-07-15.

運動トレーニングはアルツハイマー病モデルの脳血管機能障害を改善する:P2Y2受容体と小胞体ストレスの役割

Exercise training ameliorates cerebrovascular dysfunction in a murine model of Alzheimer's disease: role of the P2Y2 receptor and endoplasmic reticulum stress.
  • Junyoung Hong
  • Soon-Gook Hong
  • Jonghae Lee
  • Joon-Young Park
  • Jason L Eriksen
  • Bridgette V Rooney
  • Yoonjung Park
  • Am. J. Physiol. Heart Circ. Physiol..2020 06;318(6):H1559-H1569. doi: 10.1152/ajpheart.00129.2020.Epub 2020-05-08.

子宮内膜症関連疼痛を有する女性を対象とした第3相試験における臨床効果評価項目に対するエラゴリックス曝露の効果。マルコフモデルの応用

Effect of elagolix exposure on clinical efficacy endpoints in phase 3 trials in women with endometriosis-associated pain: An application of Markov model.
  • Insa Winzenborg
  • Akshanth R Polepally
  • Ahmed Nader
  • Nael M Mostafa
  • Peter Noertersheuser
  • Juki Ng
  • CPT Pharmacometrics Syst Pharmacol.2020 Jul;doi: 10.1002/psp4.12545.Epub 2020-07-03.

脳虚血時にはHIF1α/ZEB2軸を介してTRPC6が糸球体ポッドサイトに誘導され、蛋白尿に寄与している

Cerebral ischemia induces TRPC6 via HIF1α/ZEB2 axis in the glomerular podocytes and contributes to proteinuria.
  • Krishnamurthy Nakuluri
  • Rajkishor Nishad
  • Dhanunjay Mukhi
  • Sireesh Kumar
  • Venkata P Nakka
  • Lakshmi P Kolligundla
  • Parimala Narne
  • Sai Sampath K Natuva
  • Prakash Babu Phanithi
  • Anil K Pasupulati
  • Sci Rep.2019 11;9(1):17897. 10.1038/s41598-019-52872-5. doi: 10.1038/s41598-019-52872-5.Epub 2019-11-29.

ロングノンコーディングRNA366.2は、ヒツジ子宮内膜上皮細胞の増殖・遊走をmiR-1576のceRNAとしてWNT6をアップレギュレーションすることで制御している

Long non-coding RNA366.2 controls endometrial epithelial cell proliferation and migration by upregulating WNT6 as a ceRNA of miR-1576 in sheep uterus.
  • Xiaoxiao Gao
  • Xiaolei Yao
  • Zhibo Wang
  • Xiaohe Li
  • Xiaodan Li
  • Shiyu An
  • Zongyou Wei
  • Guomin Zhang
  • Feng Wang
  • Biochim Biophys Acta Gene Regul Mech.2020 Jul;:194606. S1874-9399(20)30189-9. doi: 10.1016/j.bbagrm.2020.194606.Epub 2020-07-14.

患者の血液管理プログラム内での術前エリスロポエチン投与は、輸血と術後貧血の両方を減少させる:プロスペクティブ観察研究

Preoperative erythropoietin within a patient blood management program decreases both blood transfusion and postoperative anemia: a prospective observational study.
  • Philippe Biboulet
  • Caroline Motais
  • Mathieu Pencole
  • Oliver Karam
  • Gaëtan Dangelser
  • Pierre Smilevitch
  • Guillaume Maissiat
  • Xavier Capdevila
  • Sophie Bringuier
  • Transfusion.2020 Jul;doi: 10.1111/trf.15900.Epub 2020-07-18.

iFRはCTOにおける深部にあるが大部分は可逆性の虚血を発見し、PCIの結果を最適化するのに役立つ

iFR uncovers profound but mostly reversible ischemia in CTOs and helps to optimize PCI results.
  • Peter Kayaert
  • Mathieu Coeman
  • Benny Drieghe
  • Johan Bennett
  • Keir McCutcheon
  • Jo Dens
  • Claudiu Ungureanu
  • Carlo Zivelonghi
  • Pierfrancesco Agostoni
  • Yoann Bataille
  • Quentin de Hemptinne
  • Sofie Gevaert
  • Michel De Pauw
  • Steven Haine
  • Catheter Cardiovasc Interv.2020 Jun;doi: 10.1002/ccd.29072.Epub 2020-06-17.

上眼窩気道装置を用いたレミフェンタニルベースの全身麻酔時におけるデスフルラン、セボフルラン、プロポフォールの眼窩開口部に対する効果の比較

Comparison of the Effects of Desflurane, Sevoflurane, and Propofol on the Glottic Opening Area during Remifentanil-Based General Anesthesia Using a Supraglottic Airway Device.
  • Takashi Kondo
  • Hiromichi Izumi
  • Makiko Kitagawa
  • Anesthesiol Res Pract.2020;2020:1302898. doi: 10.1155/2020/1302898.Epub 2020-06-19.

ミトコンドリア機能不全は骨形成を阻害し、破骨細胞の活性を高め、加齢に伴う骨量減少を促進する

Mitochondrial dysfunction impairs osteogenesis, increases osteoclast activity, and accelerates age related bone loss.
  • Philip F Dobson
  • Ella P Dennis
  • Daniel Hipps
  • Amy Reeve
  • Alex Laude
  • Carla Bradshaw
  • Craig Stamp
  • Anna Smith
  • David J Deehan
  • Doug M Turnbull
  • Laura C Greaves
  • Sci Rep.2020 Jul;10(1):11643. 10.1038/s41598-020-68566-2. doi: 10.1038/s41598-020-68566-2.Epub 2020-07-15.

思春期の青少年における運動トレーニング後の単純な体重変化を超えたインスリン感受性の変化を予測する際の心肺体力、内臓脂肪、肝脂肪の有用性の評価

Assessing the utility of cardiorespiratory fitness, visceral fat and liver fat in predicting changes in insulin sensitivity beyond simple changes in body weight after exercise training in adolescents.
  • Jennifer L Kuk
  • SoJung Lee
  • Appl Physiol Nutr Metab.2020 Jul;doi: 10.1139/apnm-2020-0284.Epub 2020-07-16.

マラウイのリロングウェにおける電子小児救急・急性期医療データベースの開発と実施から得られた教訓

Lessons learned from the development and implementation of an electronic paediatric emergency and acute care database in Lilongwe, Malawi.
  • Emily J Ciccone
  • Alyssa E Tilly
  • Msandeni Chiume
  • Yamikani Mgusha
  • Michelle Eckerle
  • Howard Namuku
  • Heather L Crouse
  • Treasure B Mkaliainga
  • Jeff A Robison
  • Charles J Schubert
  • Tisungane Mvalo
  • Elizabeth Fitzgerald
  • BMJ Glob Health.2020 Jul;5(7). e002410. doi: 10.1136/bmjgh-2020-002410.

小規模腎塊サーベイランス。生検で特徴づけられたコホートにおける組織学的に特異的な成長率

Small Renal Mass Surveillance: Histology-specific Growth Rates in a Biopsy-characterized Cohort.
  • Antonio Finelli
  • Douglas C Cheung
  • Ashraf Al-Matar
  • Andrew J Evans
  • Christopher G Morash
  • Stephen E Pautler
  • D Robert Siemens
  • Simon Tanguay
  • Ricardo A Rendon
  • Martin E Gleave
  • Darrel E Drachenberg
  • Joseph L Chin
  • Neil E Fleshner
  • Masoom A Haider
  • John R Kachura
  • Jenna Sykes
  • Michael A S Jewett
  • Eur. Urol..2020 Jul;S0302-2838(20)30513-3. doi: 10.1016/j.eururo.2020.06.053.Epub 2020-07-14.

全インド眼科学会-インド眼輪形成術協会 COVID-19 パンデミック時の眼輪形成術および涙腺外科手術における好ましい実施方法に関するコンセンサス声明

All India Ophthalmological Society - Oculoplastics Association of India consensus statement on preferred practices in oculoplasty and lacrimal surgery during the COVID-19 pandemic.
  • Mohammad Javed Ali
  • Raghuraj Hegde
  • Akshay Gopinathan Nair
  • Mandeep S Bajaj
  • Subhash M Betharia
  • Kasturi Bhattacharjee
  • Apjit K Chhabra
  • Jayanta K Das
  • Gagan Dudeja
  • Ashok K Grover
  • Santosh G Honavar
  • Usha Kim
  • Lakshmi Mahesh
  • Bipasha Mukherjee
  • Anita Sethi
  • Mukesh Sharma
  • Usha Singh
  • Indian J Ophthalmol.2020 06;68(6):974-980. IndianJOphthalmol_2020_68_6_974_284779. doi: 10.4103/ijo.IJO_1415_20.

嚢胞性線維症に対する抗菌薬スチュワードシップの関連性の発見

Finding the relevance of antimicrobial stewardship for cystic fibrosis.
  • Jonathan D Cogen
  • Barbara C Kahl
  • Holly Maples
  • Susanna A McColley
  • Jason A Roberts
  • Kevin L Winthrop
  • Andrew M Morris
  • Alison Holmes
  • Patrick A Flume
  • Donald R VanDevanter
  • Valerie Waters
  • Marianne S Muhlebach
  • J Stuart Elborn
  • Lisa Saiman
  • Scott C Bell
  • J. Cyst. Fibros..2020 Jul;19(4):511-520. S1569-1993(20)30059-X. doi: 10.1016/j.jcf.2020.02.012.Epub 2020-02-29.

ブラジルの小児固形腫瘍患者コホートにおけるTP53 p.R337H突然変異の頻度

Frequency of the TP53 p.R337H mutation in a Brazilian cohort of pediatric patients with solid tumors.
  • José Antonio da Silva Feitosa
  • Pablo Ferreira das Chagas
  • Graziella Ribeiro de Sousa
  • Rosane Gomes de Paula Queiroz
  • Gustavo Alencastro Veiga Cruzeiro
  • Luiz Gonzaga Tone
  • Kleiton Silva Borges
  • Elvis Terci Valera
  • Mol. Biol. Rep..2020 Jul;10.1007/s11033-020-05655-5. doi: 10.1007/s11033-020-05655-5.Epub 2020-07-15.

HIV神経障害性疼痛に対する薬理学的および非薬理学的介入。システマティックレビューとメタアナリシス

Pharmacologic and Non-Pharmacologic Interventions for HIV-Neuropathy Pain. A Systematic Review and a Meta-Analysis.
  • Aikaterini Amaniti
  • Chrysanthi Sardeli
  • Varvara Fyntanidou
  • Panagiota Papakonstantinou
  • Ioannis Dalakakis
  • Antonios Mylonas
  • Konstantinos Sapalidis
  • Christoforos Kosmidis
  • Athanasios Katsaounis
  • Dimitrios Giannakidis
  • Charilaos Koulouris
  • Zoi Aidoni
  • Nikolaos Michalopoulos
  • Paul Zarogoulidis
  • Isaak Kesisoglou
  • Aris Ioannidis
  • Anastasios Vagionas
  • Konstantinos Romanidis
  • Panagoula Oikonomou
  • Vasilios Grosomanidis
  • Medicina (Kaunas).2019 Nov;55(12). E762. doi: 10.3390/medicina55120762.Epub 2019-11-28.

脂肪組織は(合成)カンナビノイドの検出に適しているか?JWH-210、RCS-4、∆9-テトラヒドロカンナビノールを豚に肺投与した後の死前および死後の検体を分析した比較研究

Is adipose tissue suitable for detection of (synthetic) cannabinoids? A comparative study analyzing antemortem and postmortem specimens following pulmonary administration of JWH-210, RCS-4, as well as ∆9-tetrahydrocannabinol to pigs.
  • Nadine Schaefer
  • Frederike Nordmeier
  • Ann-Katrin Kröll
  • Christina Körbel
  • Matthias W Laschke
  • Michael D Menger
  • Hans H Maurer
  • Markus R Meyer
  • Peter H Schmidt
  • Arch. Toxicol..2020 Jul;10.1007/s00204-020-02843-x. doi: 10.1007/s00204-020-02843-x.Epub 2020-07-14.

術後CTにおける感染腹水コレクションと無菌腹水コレクション:臨床所見と画像所見に基づくスコアリングシステム

Infected versus sterile abdominal fluid collections in postoperative CT: a scoring system based on clinical and imaging findings.
  • Christoph G Radosa
  • Julia C Radosa
  • Michael Laniado
  • Julia Brandt
  • Johannes Streitzig
  • Danilo Seppelt
  • Andreas Volk
  • Verena Plodeck
  • Jens P Kühn
  • Ralf-Thorsten Hoffmann
  • Abdom Radiol (NY).2020 Jul;10.1007/s00261-020-02635-y. doi: 10.1007/s00261-020-02635-y.Epub 2020-07-16.

単純な虫垂炎に対する腹腔鏡下虫垂切除術後の術後抗生物質の静脈内投与は必要か?A Prospective Double-blinded Randomized Controlled Trial

Are Postoperative Intravenous Antibiotics Indicated After Laparoscopic Appendicectomy for Simple Appendicitis? A Prospective Double-blinded Randomized Controlled Trial.
  • Nicole Mennie
  • Gayathri Panabokke
  • Annette Chang
  • Sharman Tan Tanny
  • Wei Cheng
  • Maurizio Pacilli
  • Peter Ferguson
  • Ramesh M Nataraja
  • Ann. Surg..2020 Aug;272(2):248-252. 00000658-202008000-00057. doi: 10.1097/SLA.0000000000003732.

多発性骨髄腫の治療における免疫療法に関するがん免疫療法学会のコンセンサス声明

The Society for Immunotherapy of Cancer consensus statement on immunotherapy for the treatment of multiple myeloma.
  • Nina Shah
  • Jack Aiello
  • David E Avigan
  • Jesus G Berdeja
  • Ivan M Borrello
  • Ajai Chari
  • Adam D Cohen
  • Karthik Ganapathi
  • Lissa Gray
  • Damian Green
  • Amrita Krishnan
  • Yi Lin
  • Elisabet Manasanch
  • Nikhil C Munshi
  • Ajay K Nooka
  • Aaron P Rapoport
  • Eric L Smith
  • Ravi Vij
  • Madhav Dhodapkar
  • J Immunother Cancer.2020 Jul;8(2). e000734. doi: 10.1136/jitc-2020-000734.

イオン性およびナノ酸化亜鉛暴露に対する河川バイオフィルムコミュニティの応答に関するメタトランスクリプトームの洞察

Metatranscriptomic Insights Into the Response of River Biofilm Communities to Ionic and Nano-Zinc Oxide Exposures.
  • Jordyn Bergsveinson
  • Julie Roy
  • Christine Maynard
  • Sylvie Sanschagrin
  • Claire N Freeman
  • George D W Swerhone
  • James J Dynes
  • Julien Tremblay
  • Charles W Greer
  • Darren R Korber
  • John R Lawrence
  • Front Microbiol.2020;11:267. doi: 10.3389/fmicb.2020.00267.Epub 2020-02-26.

びまん性大細胞型B細胞リンパ腫におけるベースラインの代謝性総腫瘍負担の自動セグメンテーション:どの方法が最も効果的か?

Automated segmentation of baseline metabolic total tumor burden in diffuse large B-cell lymphoma: which method is most successful ?
  • Sally F Barrington
  • Ben Gjc Zwezerijnen
  • Henrica Cw de Vet
  • Martijn W Heymans
  • N George Mikhaeel
  • Coreline N Burggraaff
  • Jakoba J Eertink
  • Lucy C Pike
  • Otto S Hoekstra
  • Josee M Zijlstra
  • Ronald Boellaard
  • J. Nucl. Med..2020 Jul;jnumed.119.238923. doi: 10.2967/jnumed.119.238923.Epub 2020-07-17.

マラリア原虫メロゾイト表面タンパク質1(PmMSP1)の組換えタンパク質。BALB/cモデルでの免疫原性試験と診断ツールとしての利用の可能性

Recombinant proteins of Plasmodium malariae merozoite surface protein 1 (PmMSP1): Testing immunogenicity in the BALB/c model and potential use as diagnostic tool.
  • Yelina B Elizardez
  • Wesley L Fotoran
  • Andrés J Galisteo Junior
  • Izilda Curado
  • Norival Kesper Junior
  • Eliana F Monteiro
  • Irineu Romero Neto
  • Gerhard Wunderlich
  • Karin Kirchgatter
  • PLoS ONE.2019;14(7):e0219629. PONE-D-19-08555. doi: 10.1371/journal.pone.0219629.Epub 2019-07-25.

血小板活性化因子は、リゾホスファチジルコリン誘発性脱髄を、その受容体依存性および非依存性の効果を介して悪化させる

Platelet-Activating Factor Deteriorates Lysophosphatidylcholine-Induced Demyelination Via Its Receptor-Dependent and -Independent Effects.
  • Zhisen Tian
  • Tianci Chu
  • Lisa B E Shields
  • Qingsan Zhu
  • Yi Ping Zhang
  • Maiying Kong
  • Gregory N Barnes
  • Yuanyi Wang
  • Christopher B Shields
  • Jun Cai
  • Mol. Neurobiol..2020 Jul;10.1007/s12035-020-02003-3. doi: 10.1007/s12035-020-02003-3.Epub 2020-07-13.