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日本語AIでPubMedを検索

日本語AIでPubMedを検索

PubMedの提供する医学論文データベースを日本語で検索できます。AI(Deep Learning)を活用した機械翻訳エンジンにより、精度高く日本語へ翻訳された論文をご参照いただけます。

みんなが読んでいる論文

また、メタボリックシンドロームモデルマウスの脂肪組織のトランスクリプトーム解析により、疾患発症に関連する遺伝子シグネチャーを同定した

Transcriptome analysis of the adipose tissue in a mouse model of metabolic syndrome identifies gene signatures related to disease pathogenesis.
  • Dimitris Nasias
  • Katerina Dalakoura-Karagkouni
  • Despoina Vassou
  • Giorgos Papagiannakis
  • Ariadni Papadaki
  • Dimitris Kardassis
  • Genomics.2020 Jul;S0888-7543(19)31032-8. doi: 10.1016/j.ygeno.2020.06.053.Epub 2020-07-08.

COMPASS試験では、血栓透過性は吸引血栓摘出術のファーストパス成功と関連している

Clot perviousness is associated with first pass success of aspiration thrombectomy in the COMPASS trial.
  • Maxim Mokin
  • Muhammad Waqas
  • Johanna Fifi
  • Reade De Leacy
  • David Fiorella
  • Elad I Levy
  • Kenneth Snyder
  • Ricardo Hanel
  • Keith Woodward
  • Imran Chaudry
  • Ansaar T Rai
  • Donald Frei
  • Josser E Delgado Almandoz
  • Michael Kelly
  • Adam S Arthur
  • Blaise W Baxter
  • Joey English
  • Italo Linfante
  • Kyle M Fargen
  • Aquilla Turk
  • Adnan H Siddiqui
  • J Mocco
  • J Neurointerv Surg.2020 Jul;neurintsurg-2020-016434. doi: 10.1136/neurintsurg-2020-016434.Epub 2020-07-17.

血管透過性のダウンレギュレーションと炎症性・酸化性障害の保護を介した敗血症関連急性肺・腎障害に対するマンギフェリンの治療効果

Therapeutic effects of mangiferin on sepsis-associated acute lung and kidney injuries via the downregulation of vascular permeability and protection of inflammatory and oxidative damages.
  • Dong Zhang
  • Shasha Han
  • Yue Zhou
  • Boyang Qi
  • Xiaozhi Wang
  • Eur J Pharm Sci.2020 Jun;152:105400. S0928-0987(20)30189-5. doi: 10.1016/j.ejps.2020.105400.Epub 2020-06-12.

前立腺特異抗原値が上昇した高齢男性患者の病理組織学、薬物療法、前立腺悪性腫瘍の予測因子-プロスペクティブ研究

Histopathology, pharmacotherapy, and predictors of prostatic malignancy in elderly male patients with raised prostate-specific antigen levels - A prospective study.
  • Dhinesh Kumar Mathaiyan
  • Satya Prakash Tripathi
  • Jeffrey Pradeep Raj
  • Bodapati Sivaramakrishna
  • Urol Ann.2020 Apr-Jun;12(2):132-137. UA-12-132. doi: 10.4103/UA.UA_68_19.Epub 2020-04-14.

ハイスループット毒素生産戦略と組み合わせたベノミクスアプローチにより、最初のベノミクス由来メラノコルチン受容体アゴニストが同定された

A Venomics Approach Coupled to High-Throughput Toxin Production Strategies Identifies the First Venom-Derived Melanocortin Receptor Agonists.
  • Steve Reynaud
  • Justyna Ciolek
  • Michel Degueldre
  • Natalie J Saez
  • Ana Filipa Sequeira
  • Yoan Duhoo
  • Joana L A Brás
  • Hervé Meudal
  • Miguel Cabo Díez
  • Victoria Fernández Pedrosa
  • Marion Verdenaud
  • Julia Boeri
  • Oscar Pereira Ramos
  • Frédéric Ducancel
  • Margot Vanden Driessche
  • Rudy Fourmy
  • Aude Violette
  • Grégory Upert
  • Gilles Mourier
  • Annette G Beck-Sickinger
  • Karin Mörl
  • Céline Landon
  • Carlos M G A Fontes
  • Rebeca Miñambres Herráiz
  • Ricardo C Rodríguez de la Vega
  • Steve Peigneur
  • Jan Tytgat
  • Loïc Quinton
  • Edwin De Pauw
  • Renaud Vincentelli
  • Denis Servent
  • Nicolas Gilles
  • J. Med. Chem..2020 Jul;doi: 10.1021/acs.jmedchem.0c00485.Epub 2020-07-16.

希少な進行性前立腺がん変異型-腺扁平上皮がん、多形巨細胞がん、および肉腫性がん:19例の解析

Gene Fusion Characterization of Rare Aggressive Prostate Cancer Variants - Adenosquamous Carcinoma, Pleomorphic Giant Cell Carcinoma, and Sarcomatoid Carcinoma: An Analysis of 19 Cases.
  • Mohamed Alhamar
  • Tudor Vladislav
  • Steven C Smith
  • Yuan Gao
  • Liang Cheng
  • Laura A Favazza
  • Ali M Alani
  • Michael M Ittmann
  • Nicole D Riddle
  • Lisa J Whiteley
  • Nilesh S Gupta
  • Shannon Carskadon
  • Juan C Gomez-Gelvez
  • Dhananjay A Chitale
  • Nallasivam Palanisamy
  • Ondrej Hes
  • Kiril Trpkov
  • Sean R Williamson
  • Histopathology.2020 Jul;doi: 10.1111/his.14205.Epub 2020-07-08.

逆相高速液体クロマトグラフィーとパルスアンペロメトリック検出を組み合わせた、白人参中の6つの非極性ジンセノサイドの同時定量

Simultaneous quantification of six nonpolar ginsenosides in white ginseng by reverse-phase high-performance liquid chromatography coupled with integrated pulsed amperometric detection.
  • Hyeyoung Song
  • Kyung-Won Song
  • Seon-Pyo Hong
  • J Ginseng Res.2020 Jul;44(4):563-569. S1226-8453(19)30001-6. doi: 10.1016/j.jgr.2019.07.002.Epub 2019-07-26.

酸性スフィンゴミエリン酵素の直接かつ特異的な阻害剤である低分子ARC39のin vitroでの特性評価

Characterization of the small molecule ARC39, a direct and specific inhibitor of acid sphingomyelinase in vitro.
  • Eyad Naser
  • Stephanie Kadow
  • Fabian Schumacher
  • Zainelabdeen H Mohamed
  • Christian Kappe
  • Gabriele Hessler
  • Barbara Pollmeier
  • Burkhard Kleuser
  • Christoph Arenz
  • Katrin Anne Becker
  • Erich Gulbins
  • Alexander Carpinteiro
  • J. Lipid Res..2020 Jun;61(6):896-910. jlr.RA120000682. doi: 10.1194/jlr.RA120000682.Epub 2020-03-10.

血漿中および気管支肺胞液中の IL-17A および IL-35 のレベルの上昇は、非小細胞肺がん患者におけるチェックポイント阻害剤肺炎と関連している

Elevated levels of IL-17A and IL-35 in plasma and bronchoalveolar lavage fluid are associated with checkpoint inhibitor pneumonitis in patients with non-small cell lung cancer.
  • Yi Na Wang
  • Dan Feng Lou
  • Dan Yang Li
  • Wei Jiang
  • Jing Yin Dong
  • Wei Gao
  • Hong Chao Chen
  • Oncol Lett.2020 Jul;20(1):611-622. OL-0-0-11618. doi: 10.3892/ol.2020.11618.Epub 2020-05-13.

緑膿菌を標的とした工学的低分子ピリンの免疫増強:免疫情報学的調査と積極的な免疫化の組み合わせ

Immunopotentiation of the engineered low-molecular-weight pilin targeting Pseudomonas aeruginosa: A combination of immunoinformatics investigation and active immunization.
  • Yasaman Ahmadbeigi
  • Alireza Salimi Chirani
  • Neda Soleimani
  • Mehdi Mahdavi
  • Mehdi Goudarzi
  • Mol. Immunol..2020 Aug;124:70-82. S0161-5890(20)30350-3. doi: 10.1016/j.molimm.2020.05.009.Epub 2020-06-12.

膵頭十二指腸摘術後の術前赤血球平均コルプスキュラー容積と感染症合併症との間に有意な関連があることを示した

Significant association between the preoperative erythrocyte mean corpuscular volume and infectious complications after pancreaticoduodenectomy.
  • Katsunori Sakamoto
  • Kohei Ogawa
  • Hitoshi Inoue
  • Mikiya Shine
  • Takashi Matsui
  • Yusuke Nishi
  • Takeshi Utsunomiya
  • Kei Tamura
  • Akihiro Takai
  • Yasutsugu Takada
  • Surg. Today.2020 Jul;10.1007/s00595-020-02083-7. doi: 10.1007/s00595-020-02083-7.Epub 2020-07-17.

サハラ以南のアフリカにおける低窒素投入条件でのトウモロコシ収量に対する気候変動の影響をモデル化する

Modelling climate change impacts on maize yields under low nitrogen input conditions in sub-Saharan Africa.
  • G N Falconnier
  • M Corbeels
  • K J Boote
  • F Affholder
  • M Adam
  • D S MacCarthy
  • A C Ruane
  • C Nendel
  • A M Whitbread
  • E Justes
  • L R Ahuja
  • F M Akinseye
  • I N Alou
  • K A Amouzou
  • S S Anapalli
  • C Baron
  • B Basso
  • F Baudron
  • P Bertuzzi
  • A J Challinor
  • Y Chen
  • D Deryng
  • M L Elsayed
  • B Faye
  • T Gaiser
  • M Galdos
  • S Gayler
  • E Gerardeaux
  • M Giner
  • B Grant
  • G Hoogenboom
  • E S Ibrahim
  • B Kamali
  • K C Kersebaum
  • S H Kim
  • M van der Laan
  • L Leroux
  • J I Lizaso
  • B Maestrini
  • E A Meier
  • F Mequanint
  • A Ndoli
  • C H Porter
  • E Priesack
  • D Ripoche
  • T Sida
  • U Singh
  • W Smith
  • A Srivastava
  • S Sinha
  • F Tao
  • P J Thorburn
  • D Timlin
  • B Traore
  • T Twine
  • H Webber
  • Glob Chang Biol.2020 Jul;doi: 10.1111/gcb.15261.Epub 2020-07-06.

膀胱癌に対する根治的膀胱摘出術後の補助化学療法のタイミングが患者の生存に及ぼす影響

Impact of timing of adjuvant chemotherapy following radical cystectomy for bladder cancer on patient survival.
  • Camilla M Grunewald
  • Alina Henn
  • Matthew D Galsky
  • Elizabeth R Plimack
  • Lauren C Harshman
  • Evan Y Yu
  • Simon J Crabb
  • Sumanta K Pal
  • Ajjai Shivaram Alva
  • Thomas Powles
  • Ugo De Giorgi
  • Neeraj Agarwal
  • Aristotelis Bamias
  • Sylvain Ladoire
  • Andrea Necchi
  • Ulka N Vaishampayan
  • Cora N Sternberg
  • Joaquim Bellmunt
  • Jack Baniel
  • Guenter Niegisch
  • Urol. Oncol..2020 Jul;S1078-1439(20)30276-3. doi: 10.1016/j.urolonc.2020.06.008.Epub 2020-07-10.

NPHS1およびTNFSF15における共通のリスクバリアントは、小児ステロイド感受性ネフローゼ症候群と関連している

Common risk variants in NPHS1 and TNFSF15 are associated with childhood steroid-sensitive nephrotic syndrome.
  • Xiaoyuan Jia
  • Tomohiko Yamamura
  • Rasheed Gbadegesin
  • Michelle T McNulty
  • Kyuyong Song
  • China Nagano
  • Yuki Hitomi
  • Dongwon Lee
  • Yoshihiro Aiba
  • Seik-Soon Khor
  • Kazuko Ueno
  • Yosuke Kawai
  • Masao Nagasaki
  • Eisei Noiri
  • Tomoko Horinouchi
  • Hiroshi Kaito
  • Riku Hamada
  • Takayuki Okamoto
  • Koichi Kamei
  • Yoshitsugu Kaku
  • Rika Fujimaru
  • Ryojiro Tanaka
  • Yuko Shima
  • Jiwon Baek
  • Hee Gyung Kang
  • Il-Soo Ha
  • Kyoung Hee Han
  • Eun Mi Yang
  • Asiri Abeyagunawardena
  • Brandon Lane
  • Megan Chryst-Stangl
  • Christopher Esezobor
  • Adaobi Solarin
  • Claire Dossier
  • Georges Deschênes
  • Marina Vivarelli
  • Hanna Debiec
  • Kenji Ishikura
  • Masafumi Matsuo
  • Kandai Nozu
  • Pierre Ronco
  • Hae Il Cheong
  • Matthew G Sampson
  • Katsushi Tokunaga
  • Kazumoto Iijima
  • Kidney Int..2020 Jun;S0085-2538(20)30639-6. doi: 10.1016/j.kint.2020.05.029.Epub 2020-06-14.

HIV 感染症患者におけるグローバルな炎症マーカーとして H-NMR で評価された糖タンパク質プロファイル。プロスペクティブ研究

Glycoprotein Profile Assessed by H-NMR as a Global Inflammation Marker in Patients with HIV Infection. A Prospective Study.
  • Ana-Irene Malo
  • Anna Rull
  • Josefa Girona
  • Pere Domingo
  • Rocío Fuertes-Martín
  • Núria Amigó
  • Cèlia Rodríguez-Borjabad
  • Neus Martínez-Micaelo
  • Manuel Leal
  • Joaquim Peraire
  • Xavier Correig
  • Francesc Vidal
  • Lluis Masana
  • J Clin Med.2020 May;9(5). E1344. doi: 10.3390/jcm9051344.Epub 2020-05-04.

コントロールされた卵巣刺激とプロゲステロン補充は体外受精サイクルにおける膣および子宮内膜微生物叢に影響を与える:パイロット研究

Controlled ovarian stimulation and progesterone supplementation affect vaginal and endometrial microbiota in IVF cycles: a pilot study.
  • Andrea Carosso
  • Alberto Revelli
  • Gianluca Gennarelli
  • Stefano Canosa
  • Stefano Cosma
  • Fulvio Borella
  • Annalisa Tancredi
  • Carlotta Paschero
  • Lara Boatti
  • Elisa Zanotto
  • Francesca Sidoti
  • Paolo Bottino
  • Cristina Costa
  • Rossana Cavallo
  • Chiara Benedetto
  • J. Assist. Reprod. Genet..2020 Jul;10.1007/s10815-020-01878-4. doi: 10.1007/s10815-020-01878-4.Epub 2020-07-15.

アスパラギナーゼ遺伝子の発現がコナジラミに対する殺虫活性を誘発することを明らかにした

Constitutive expression of Asparaginase in Gossypium hirsutum triggers insecticidal activity against Bemisia tabaci.
  • Ambreen Gul
  • Ghulam Hussain
  • Adnan Iqbal
  • Abdul Qayyum Rao
  • Salah Ud Din
  • Aneela Yasmeen
  • Naila Shahid
  • Ammara Ahad
  • Ayesha Latif
  • Saira Azam
  • Tahir Rehman Samiullah
  • Samina Hassan
  • Ahmad Ali Shahid
  • Tayyab Husnain
  • Sci Rep.2020 Jun;10(1):8958. 10.1038/s41598-020-65249-w. doi: 10.1038/s41598-020-65249-w.Epub 2020-06-02.

染色体22q11.2欠失症候群患者における非定型多糖カプセルを有する肺炎球菌血清型10Aによる致死的圧迫性脾臓摘出後感染症。症例報告

Fatal overwhelming postsplenectomy infection due to Streptococcus pneumoniae serotype 10A with atypical polysaccharide capsule in a patient with chromosome 22q11.2 deletion syndrome: A case report.
  • Keiko Matsuoka
  • Itaru Yanagihara
  • Yukiko Kawazu
  • Maho Sato
  • Masahiro Nakayama
  • Yukiko Nakura
  • Nao Kanagawa
  • Yukihiro Akeda
  • Futoshi Fujiwara
  • Kazutoshi Itoh
  • Hiroaki Kawata
  • Makoto Takeuchi
  • J. Infect. Chemother..2019 Mar;25(3):192-196. S1341-321X(18)30236-8. doi: 10.1016/j.jiac.2018.07.015.Epub 2018-08-29.

トランスクリプトーム解析とinVivo発生との比較解析により明らかになったシグナル伝達経路の変調による網膜オルガノイド分化の改善

Improved Retinal Organoid Differentiation by Modulating Signaling Pathways Revealed by Comparative Transcriptome Analyses with Development In Vivo.
  • Matthew J Brooks
  • Holly Y Chen
  • Ryan A Kelley
  • Anupam K Mondal
  • Kunio Nagashima
  • Natalia De Val
  • Tiansen Li
  • Vijender Chaitankar
  • Anand Swaroop
  • Stem Cell Reports.2019 11;13(5):891-905. S2213-6711(19)30338-8. doi: 10.1016/j.stemcr.2019.09.009.Epub 2019-10-17.

(モノ)研磨剤産業におけるナフタレンへの曝露.大気モニタリングと生物学的モニタリング

(Mono-) Exposure to Naphthalene in the Abrasives Industry: Air Monitoring and Biological Monitoring.
  • Tobias Weiss
  • Dietmar Breuer
  • Daniel Bury
  • Claudia Friedrich
  • Silke Werner
  • Mohammed Aziz
  • Thomas Hummel
  • Monika Raulf
  • Wolfgang Zschiesche
  • Kirsten Sucker
  • Dirk Pallapies
  • Jürgen Bünger
  • Thomas Brüning
  • Ann Work Expo Health.2020 Jul;wxaa062. doi: 10.1093/annweh/wxaa062.Epub 2020-07-13.

侵襲的中隔縮小療法のタイミングと閉塞性肥大型心筋症患者の転帰

Timing of invasive septal reduction therapies and outcome of patients with obstructive hypertrophic cardiomyopathy.
  • Luna Cavigli
  • Carlo Fumagalli
  • Niccolò Maurizi
  • Alessandra Rossi
  • Anna Arretini
  • Mattia Targetti
  • Silvia Passantino
  • Francesca Girolami
  • Benedetta Tomberli
  • Katia Baldini
  • Alessia Tomberli
  • David Antoniucci
  • Magdi H Yacoub
  • Niccolò Marchionni
  • Pier Luigi Stefano
  • Franco Cecchi
  • Iacopo Olivotto
  • Int. J. Cardiol..2018 Dec;273:155-161. S0167-5273(18)30575-8. doi: 10.1016/j.ijcard.2018.09.004.Epub 2018-09-05.

機能化グラフェンナノ粒子によるヒト間葉系幹細胞の細胞外マトリックス蛋白質の発現を誘導し、骨形成を促進する

Functionalized Graphene Nanoparticles Induce Human Mesenchymal Stem Cells to Express Distinct Extracellular Matrix Proteins Mediating Osteogenesis.
  • Steven D Newby
  • Tom Masi
  • Christopher D Griffin
  • William J King
  • Anna Chipman
  • Stacy Stephenson
  • David E Anderson
  • Alexandru S Biris
  • Shawn E Bourdo
  • Madhu Dhar
  • Int J Nanomedicine.2020;15:2501-2513. 245801. doi: 10.2147/IJN.S245801.Epub 2020-04-15.

インターフェロン-αおよびToll-like Receptor-3活性化誘発マウスうつ病モデルにおける海馬神経可塑性の低下

Compromised Hippocampal Neuroplasticity in the Interferon-α and Toll-like Receptor-3 Activation-Induced Mouse Depression Model.
  • Eduardo H Sanchez-Mendoza
  • Santiago Camblor-Perujo
  • Luiza Martins Nascentes-Melo
  • Egor Dzyubenko
  • Michael Fleischer
  • Tayana Silva de Carvalho
  • Linda-Isabell Schmitt
  • Markus Leo
  • Tim Hagenacker
  • Arne Herring
  • Kathy Keyvani
  • Sujoy Bera
  • Natalia Kononenko
  • Christoph Kleinschnitz
  • Dirk M Hermann
  • Mol. Neurobiol..2020 Jul;57(7):3171-3182. 10.1007/s12035-020-01927-0. doi: 10.1007/s12035-020-01927-0.Epub 2020-06-05.

ボルテゾミブとテモゾロミドの併用療法は、臨床成績が良好な膠芽腫患者の免疫反応を促進する。第1B相試験

Sequential bortezomib and temozolomide treatment promotes immunological responses in glioblastoma patients with positive clinical outcomes: A phase 1B study.
  • Mohummad A Rahman
  • Jorunn Brekke
  • Victoria Arnesen
  • Marianne H Hannisdal
  • Andrea G Navarro
  • Andreas Waha
  • Lars Herfindal
  • Cecilie B Rygh
  • Eirik Bratland
  • Petter Brandal
  • Judit Haasz
  • Leif Oltedal
  • Hrvoje Miletic
  • Arvid Lundervold
  • Stein A Lie
  • Dorota Goplen
  • Martha Chekenya
  • Immun Inflamm Dis.2020 Jun;doi: 10.1002/iid3.315.Epub 2020-06-24.

高額医療保険に加入している高額医療サービス利用のリスクがある炎症性腸疾患患者における医療利用パターンの変動

Variations in Health Care Utilization Patterns Among Inflammatory Bowel Disease Patients at Risk for High Medical Service Utilization Enrolled in High Deductible Health Plans.
  • Jeffrey A Berinstein
  • Shirley A Cohen-Mekelburg
  • Calen A Steiner
  • Megan McLeod
  • Mohamed Noureldin
  • John I Allen
  • Jeffrey T Kullgren
  • Akbar K Waljee
  • Peter D R Higgins
  • Inflamm. Bowel Dis..2020 Jul;izaa179. doi: 10.1093/ibd/izaa179.Epub 2020-07-17.

難治性慢性クラスター性頭痛の治療のためのオナボツリヌストキシンAの海綿体神経節への注射の非盲検、多用量、パイロット安全性試験

Open-Label, Multi-Dose, Pilot Safety Study of Injection of OnabotulinumtoxinA Toward the Otic Ganglion for the Treatment of Intractable Chronic Cluster Headache.
  • Joan Crespi
  • Daniel Bratbak
  • David W Dodick
  • Manjit Matharu
  • Ole Solheim
  • Sasha Gulati
  • Erik Magnus Berntsen
  • Erling Tronvik
  • Headache.2020 Jun;doi: 10.1111/head.13889.Epub 2020-06-25.

HPV ワクチン接種後の原因不明の有害事象は感染性単核球症と関連しているか?- デンマークの全国的なマッチドケースコントロール研究

Are unexplained adverse health events following HPV vaccination associated with infectious mononucleosis? - A Danish nationwide matched case-control study.
  • Lene Wulff Krogsgaard
  • Ida Glode Helmuth
  • Bodil Hammer Bech
  • Oleguer Plana-Ripoll
  • Tina Hovgaard Lützen
  • Hanne Thang Vestergaard
  • Karsten Dalsgaard Bjerre
  • Reimar Wernich Thomsen
  • Kåre Mølbak
  • Dorte Rytter
  • Vaccine.2020 Jul;S0264-410X(20)30843-4. doi: 10.1016/j.vaccine.2020.06.057.Epub 2020-07-02.

グロビン共役型ジグアニル酸シクラーゼYddVの速度論的解析:ヘム鉄酸化還元状態、軸方向リガンド、ヘム遠位変異が触媒作用に及ぼす影響

Kinetic analysis of a globin-coupled diguanylate cyclase, YddV: Effects of heme iron redox state, axial ligands, and heme distal mutations on catalysis.
  • Alzbeta Lengalova
  • Veronika Fojtikova-Proskova
  • Jakub Vavra
  • Václav Martínek
  • Martin Stranava
  • Toru Shimizu
  • Marketa Martinkova
  • J. Inorg. Biochem..2019 12;201:110833. S0162-0134(19)30398-8. doi: 10.1016/j.jinorgbio.2019.110833.Epub 2019-09-06.

ゴナドトロピン放出ホルモンアゴニストとホルモン補充療法の併用は、高齢者における凍結融解胚移植サイクルの生殖成績を改善しなかった:レトロスペクティブ研究

Gonadotropin-releasing hormone agonist combined with hormone replacement therapy does not improve the reproductive outcomes of frozen-thawed embryo transfer cycle in elderly patients: a retrospective study.
  • Mei Dong
  • Li Sun
  • Li Huang
  • Yanhong Yi
  • Xiqian Zhang
  • Ying Tan
  • Ge Song
  • Liling Liu
  • Fu Wei
  • Fenghua Liu
  • Reprod. Biol. Endocrinol..2020 Jul;18(1):73. 10.1186/s12958-020-00626-8. doi: 10.1186/s12958-020-00626-8.Epub 2020-07-15.

中東最古の石油精製地帯の土壌に含まれる潜在的な有害元素:供給源の配分、スペシエーション、バイオアクセス性、およびヒトの健康リスク評価

Potentially toxic elements in the Middle East oldest oil refinery zone soils: source apportionment, speciation, bioaccessibility and human health risk assessment.
  • Zeinab Mokhtarzadeh
  • Behnam Keshavarzi
  • Farid Moore
  • Franco Ajmone Marsan
  • Elio Padoan
  • Environ Sci Pollut Res Int.2020 Jul;10.1007/s11356-020-09895-7. doi: 10.1007/s11356-020-09895-7.Epub 2020-07-15.

内分泌かく乱物質の光分解のための効率的な広スペクトル駆動型炭素・酸素共添加g-CNの開発メカニズム,分解経路,DFT計算,トルエン選択的酸化

An efficient broad spectrum-driven carbon and oxygen co-doped g-CN for the photodegradation of endocrine disrupting: Mechanism, degradation pathway, DFT calculation and toluene selective oxidation.
  • Liquan Jing
  • Duidui Wang
  • Minqiang He
  • Yuanguo Xu
  • Meng Xie
  • Yanhua Song
  • Hui Xu
  • Huaming Li
  • J. Hazard. Mater..2020 Jun;401:123309. S0304-3894(20)31298-X. doi: 10.1016/j.jhazmat.2020.123309.Epub 2020-06-27.

超微細な二酸化ケイ素ナノ粒子は、酸化ストレスによって活性化されたPI3K/Aktを介したミトコンドリアおよび小胞体ストレス依存性のシグナル伝達経路を介して肺上皮細胞のアポトーシスを引き起こす

Ultrafine silicon dioxide nanoparticles cause lung epithelial cells apoptosis via oxidative stress-activated PI3K/Akt-mediated mitochondria- and endoplasmic reticulum stress-dependent signaling pathways.
  • Kuan-I Lee
  • Chin-Chuan Su
  • Kai-Min Fang
  • Chin-Ching Wu
  • Cheng-Tien Wu
  • Ya-Wen Chen
  • Sci Rep.2020 Jun;10(1):9928. 10.1038/s41598-020-66644-z. doi: 10.1038/s41598-020-66644-z.Epub 2020-06-18.

ナイジェリア、ザリアにあるAhmadu Bello University Teaching Hospitalの放射線治療・腫瘍学センターに通院している成人がん患者に見られる腫瘍学的緊急事態のパターン

Pattern of oncologic emergencies seen in adult cancer patients attending the Radiotherapy and Oncology Centre, Ahmadu Bello University Teaching Hospital, Zaria - Nigeria.
  • S A Adewuyi
  • A T Ajekigbe
  • O B Campbell
  • N H Mbibu
  • A O Oguntayo
  • A O D Kolawole
  • A Usman
  • M O A Samaila
  • S M Shehu
  • Niger Postgrad Med J.2012 Dec;19(4):208-14.

Ta および T1 膀胱癌に対する膀胱内投与の Bacillus Calmette-Guérin 対 mitomycin C.コクランレビューの要約

Intravesical Bacillus Calmette-Guérin versus mitomycin C for Ta and T1 bladder cancer: Abridged summary of the Cochrane Review.
  • Stefanie Schmidt
  • Frank Kunath
  • Bernadette Coles
  • Desiree Louise Draeger
  • Laura-Maria Krabbe
  • Rick Dersch
  • Samuel Kilian
  • Katrin Jensen
  • Philipp Dahm
  • Joerg J Meerpohl
  • Investig Clin Urol.2020 Jul;61(4):349-354. doi: 10.4111/icu.2020.61.4.349.Epub 2020-06-29.

Plasmodium falciparum Hsp70-Hsp90 組織化タンパク質 (PfHop) の生物物理学的解析により、柔軟性のあるリンカーで連結された折り畳みセグメントが特徴のモノマーが明らかになりました

Biophysical analysis of Plasmodium falciparum Hsp70-Hsp90 organising protein (PfHop) reveals a monomer that is characterised by folded segments connected by flexible linkers.
  • Stanley Makumire
  • Tawanda Zininga
  • Juha Vahokoski
  • Inari Kursula
  • Addmore Shonhai
  • PLoS ONE.2020;15(4):e0226657. PONE-D-19-33340. doi: 10.1371/journal.pone.0226657.Epub 2020-04-28.

ペルーのピウラで先天性一般化リポジストロフィーの高い有病率

High prevalence of congenital generalized lipodystrophy in Piura, Peru.
  • Nelson David Purizaca-Rosillo
  • Yamalí Elena Benites-Cóndor
  • Hugo Abarca Barriga
  • Carlos Del Águila Villar
  • Miguel Chávez Pastor
  • Littner Franco Palacios
  • Ricardo Olea Zapata
  • James Rejas Parodi
  • Luz Martinez Uceda
  • Felix Chavesta Velásquez
  • John Gamarra Vilela
  • Sebastián Arámbulo Castillo
  • Amanda Ávila Reyes
  • Intractable Rare Dis Res.2020 Feb;9(1):58-60. doi: 10.5582/irdr.2020.01004.

思春期早発症の診断:思春期早発症の診断と治療のための臨床ガイドライン

Diagnosis of precocious puberty: clinical guideline for the diagnosis and treatment of precocious puberty.
  • América L Miranda-Lora
  • Margarita Torres-Tamayo
  • Jessie N Zurita-Cruz
  • Blanca E Aguilar-Herrera
  • Raúl Calzada-León
  • Aleida J Rivera-Hernández
  • Marco A Morales-Pérez
  • Miriam M Padrón-Martínez
  • María L Ruiz-Reyes
  • Leticia M García-Morales
  • Consuelo Barrón-Uribe
  • Sletza L Arguinzoniz-Valenzuela
  • Mayra C Torres-Castañeda
  • Lorena Lizárraga-Paulin
  • Jorge A Núñez-Hernández
  • Judith Cornejo-Barrera
  • María T Vidal-González
  • María R Martínez-Alvarado
  • Elisa Nishimura-Meguro
  • Luz E Bravo-Ríos
  • Eulalia P Garrido-Magaña
  • José A Orozco-Morales
  • Patricia G Medina-Bravo
  • Ninel Coyote-Estrada
  • M Fernanda Castilla-Peón
  • Bol Med Hosp Infant Mex.2020;77(Supl 1):7-14. j77/Supl 1/7. doi: 10.24875/BMHIM.20000075.

インディアンラッセル毒由来の神経成長因子(RVV-NGFa)は、乳がん細胞に発現するTrkA受容体に高親和性で結合している。蛍光標識RVVV-NGFaの乳がん臨床診断への応用

Nerve growth factor from Indian Russell's viper venom (RVV-NGFa) shows high affinity binding to TrkA receptor expressed in breast cancer cells: Application of fluorescence labeled RVV-NGFa in the clinical diagnosis of breast cancer.
  • Taufikul Islam
  • Munmi Majumder
  • Anil Bidkar
  • Siddhartha S Ghosh
  • Rupak Mukhopadhyay
  • Yuri Utkin
  • Ashis K Mukherjee
  • Biochimie.2020 Jun;176:31-44. S0300-9084(20)30136-X. doi: 10.1016/j.biochi.2020.06.004.Epub 2020-06-23.

カドミウム誘発性生殖毒性ラットの精子指標、アクロソーム反応、精子DNA完全性に及ぼすカルポロビア・リュテアのメタノール根抽出物の影響について検討した

Effects of the methanol root extract of Carpolobia lutea on sperm indices, acrosome reaction, and sperm DNA integrity in cadmium-induced reproductive toxicity in male Wistar rats.
  • Adeniran Oluwadamilare Akinola
  • Adekunle Wahab Oyeyemi
  • Oluyemi O Daramola
  • Yinusa Raji
  • JBRA Assist Reprod.2020 Jun;doi: 10.5935/1518-0557.20200036.Epub 2020-06-08.

カベオリン-1アブレーションは、実験緑内障における網膜内損傷に対する部分的な保護とアポトーシス活性化を減少させる

Caveolin-1 Ablation Imparts Partial Protection Against Inner Retinal Injury in Experimental Glaucoma and Reduces Apoptotic Activation.
  • Mojdeh Abbasi
  • Vivek K Gupta
  • Nitin Chitranshi
  • Veer B Gupta
  • Mehdi Mirzaei
  • Yogita Dheer
  • Linda Garthwaite
  • Thiri Zaw
  • Robert G Parton
  • Yuyi You
  • Stuart L Graham
  • Mol. Neurobiol..2020 Jun;10.1007/s12035-020-01948-9. doi: 10.1007/s12035-020-01948-9.Epub 2020-06-23.

拡大された分子系統と形態学的解析から、シダ科デンシュタットリア属の進化に新たな知見が得られた

New insights into the evolution of the fern family Dennstaedtiaceae from an expanded molecular phylogeny and morphological analysis.
  • Pedro B Schwartsburd
  • Leon R Perrie
  • Patrick Brownsey
  • Lara D Shepherd
  • Hui Shang
  • David S Barrington
  • Michael A Sundue
  • Mol. Phylogenet. Evol..2020 Jun;150:106881. S1055-7903(20)30153-6. doi: 10.1016/j.ympev.2020.106881.Epub 2020-06-06.

急性視神経炎(MOVING)の最初の片側エピソードの後の Fingolimod - 無作為化、評価者盲検、活性化対照、第2相試験の予備的な結果

Fingolimod after a first unilateral episode of acute optic neuritis (MOVING) - preliminary results from a randomized, rater-blind, active-controlled, phase 2 trial.
  • Christian Albert
  • Janine Mikolajczak
  • Anja Liekfeld
  • Sophie K Piper
  • Michael Scheel
  • Hanna G Zimmermann
  • Claus Nowak
  • Jan Dörr
  • Judith Bellmann-Strobl
  • Claudia Chien
  • Alexander U Brandt
  • Friedemann Paul
  • Olaf Hoffmann
  • BMC Neurol.2020 Mar;20(1):75. 10.1186/s12883-020-01645-z. doi: 10.1186/s12883-020-01645-z.Epub 2020-03-03.

非アレルギー性およびアレルギー性ドナーのヒト初代鼻上皮細胞の物理的および免疫学的バリアー

Physical and immunological barrier of human primary nasal epithelial cells from non-allergic and allergic donors.
  • Carolin Bergougnan
  • Daniela C Dittlein
  • Elke Hümmer
  • Rosalie Riepl
  • Selina Eisenbart
  • Dominik Böck
  • Lena Griesbaum
  • Anna Weigl
  • Athanasios Damialis
  • Alexander Hartwig
  • Avidan U Neumann
  • Johannes Zenk
  • Claudia Traidl-Hoffmann
  • Stefanie Gilles
  • World Allergy Organ J.2020 Mar;13(3):100109. S1939-4551(20)30012-0. doi: 10.1016/j.waojou.2020.100109.Epub 2020-03-09.

活性化プロトロンビン複合体濃縮物は、抗凝固剤関連出血または緊急手術前の直接経口投与のためのものです。止血および血栓症の転帰

Activated prothrombin complex concentrates for direct oral anticoagulant-associated bleeding or urgent surgery: Hemostatic and thrombotic outcomes.
  • Joseph R Shaw
  • Marc Carrier
  • Dar Dowlatshahi
  • Santanu Chakraborty
  • Melanie Tokessy
  • Hakan Buyukdere
  • Lana A Castellucci
  • Thromb. Res..2020 Jul;195:21-28. S0049-3848(20)30286-3. doi: 10.1016/j.thromres.2020.06.044.Epub 2020-07-01.