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日本語AIでPubMedを検索

日本語AIでPubMedを検索

PubMedの提供する医学論文データベースを日本語で検索できます。AI(Deep Learning)を活用した機械翻訳エンジンにより、精度高く日本語へ翻訳された論文をご参照いただけます。

みんなが読んでいる論文

また、BR 欠損変異体の比較リン酸化プロテオーム解析により、GhSK13 が綿繊維の発育を制御する上で重要な役割を果たしていることが明らかになりました

Comparative phosphoproteomic analysis of BR-defective mutant reveals a key role of GhSK13 in regulating cotton fiber development.
  • Lingling Wang
  • Han Cheng
  • Fangjie Xiong
  • Shuya Ma
  • Lei Zheng
  • Yun Song
  • Kexuan Deng
  • Huanhuan Wu
  • Fuguang Li
  • Zuoren Yang
  • Sci China Life Sci.2020 Jul;10.1007/s11427-020-1728-9. doi: 10.1007/s11427-020-1728-9.Epub 2020-07-03.

極端な高尿酸血症は、透析患者の感染症関連死の危険因子である:多施設プロスペクティブコホート研究

Extreme hyperuricemia is a risk factor for infection-related deaths in incident dialysis patients: a multicenter prospective cohort study.
  • Hiroyuki Yoshida
  • Daijo Inaguma
  • Eri Koshi-Ito
  • Soshiro Ogata
  • Akimitsu Kitagawa
  • Kazuo Takahashi
  • Shigehisa Koide
  • Hiroki Hayashi
  • Midori Hasegawa
  • Yukio Yuzawa
  • Naotake Tsuboi
  • Ren Fail.2020 Nov;42(1):646-655. doi: 10.1080/0886022X.2020.1788582.

制御された薬物送達のための温度感受性生体適合性構造としての磁気的に活性なpNIPAMナノシステム

Magnetically active pNIPAM nanosystems as temperature-sensitive biocompatible structures for controlled drug delivery.
  • Beatriz Garcia-Pinel
  • Alicia Ortega-Rodríguez
  • Cristina Porras-Alcalá
  • Laura Cabeza
  • Rafael Contreras-Cáceres
  • Raul Ortiz
  • Amelia Díaz
  • Ana Moscoso
  • Francisco Sarabia
  • José Prados
  • Juan M López-Romero
  • Consolación Melguizo
  • Artif Cells Nanomed Biotechnol.2020 Dec;48(1):1022-1035. doi: 10.1080/21691401.2020.1773488.

セルロースナノファイバー基板上に不均一に集積されたフレキシブルマイクロ波増幅器

Heterogeneously integrated flexible microwave amplifiers on a cellulose nanofibril substrate.
  • Huilong Zhang
  • Jinghao Li
  • Dong Liu
  • Seunghwan Min
  • Tzu-Hsuan Chang
  • Kanglin Xiong
  • Sung Hyun Park
  • Jisoo Kim
  • Yei Hwan Jung
  • Jeongpil Park
  • Juhwan Lee
  • Jung Han
  • Linda Katehi
  • Zhiyong Cai
  • Shaoqin Gong
  • Zhenqiang Ma
  • Nat Commun.2020 Jun;11(1):3118. 10.1038/s41467-020-16957-4. doi: 10.1038/s41467-020-16957-4.Epub 2020-06-19.

側方筋膜裂断裂はACL損傷によく見られる。600人の連続した患者の関節鏡下断裂パターンに基づく分類システム

Lateral Meniscal Oblique Radial Tears Are Common With ACL Injury: A Classification System Based on Arthroscopic Tear Patterns in 600 Consecutive Patients.
  • Aaron J Krych
  • Matthew D LaPrade
  • Corey S Cook
  • Devin Leland
  • Lucas K Keyt
  • Michael J Stuart
  • Patrick A Smith
  • Orthop J Sports Med.2020 May;8(5):2325967120921737. 10.1177_2325967120921737. doi: 10.1177/2325967120921737.Epub 2020-05-19.

地理的に異なる種類のプロポリスとブラックコットンウッド樹脂の口腔内連鎖球菌、膣内微生物、植物病原性フザリウム種に対するフェノール組成と生物学的活性

Phenolic composition and biological activities of geographically different type of propolis and black cottonwood resins against oral streptococci, vaginal microbiota and phytopathogenic Fusarium species.
  • P Ristivojević
  • T Stević
  • M Starović
  • S Pavlović
  • M M Özcan
  • T Berić
  • I Dimkić
  • J. Appl. Microbiol..2020 Aug;129(2):296-310. doi: 10.1111/jam.14633.Epub 2020-03-22.

SARS-CoV-2の不活化ワクチン候補の開発

Development of an inactivated vaccine candidate for SARS-CoV-2.
  • Qiang Gao
  • Linlin Bao
  • Haiyan Mao
  • Lin Wang
  • Kangwei Xu
  • Minnan Yang
  • Yajing Li
  • Ling Zhu
  • Nan Wang
  • Zhe Lv
  • Hong Gao
  • Xiaoqin Ge
  • Biao Kan
  • Yaling Hu
  • Jiangning Liu
  • Fang Cai
  • Deyu Jiang
  • Yanhui Yin
  • Chengfeng Qin
  • Jing Li
  • Xuejie Gong
  • Xiuyu Lou
  • Wen Shi
  • Dongdong Wu
  • Hengming Zhang
  • Lang Zhu
  • Wei Deng
  • Yurong Li
  • Jinxing Lu
  • Changgui Li
  • Xiangxi Wang
  • Weidong Yin
  • Yanjun Zhang
  • Chuan Qin
  • Science.2020 07;369(6499):77-81. science.abc1932. doi: 10.1126/science.abc1932.Epub 2020-05-06.

ミトコンドリアORFansの多様性は、淡水イガイ科(Bivalvia: Unionida)の間でミトコンドリアの二重一親遺伝の仕組みが異なる可能性を示唆している

Variability of mitochondrial ORFans hints at possible differences in the system of doubly uniparental inheritance of mitochondria among families of freshwater mussels (Bivalvia: Unionida).
  • Davide Guerra
  • Manuel Lopes-Lima
  • Elsa Froufe
  • Han Ming Gan
  • Paz Ondina
  • Rafaela Amaro
  • Michael W Klunzinger
  • Claudia Callil
  • Vincent Prié
  • Arthur E Bogan
  • Donald T Stewart
  • Sophie Breton
  • BMC Evol. Biol..2019 12;19(1):229. 10.1186/s12862-019-1554-5. doi: 10.1186/s12862-019-1554-5.Epub 2019-12-19.

ドキシサイクリン系高分子ナノ粒子の合成と抗腫瘍活性.固形エルリッヒ癌における腫瘍アポトーシスへの影響

Synthesis and Antitumor Activity of Doxycycline Polymeric Nanoparticles: Effect on Tumor Apoptosis in Solid Ehrlich Carcinoma.
  • Ahmed R Gardouh
  • Mohammed A Attia
  • Eman T Enan
  • Alaaeldeen M Elbahaie
  • Rania A Fouad
  • Mohamed El-Shafey
  • Amal M Youssef
  • Suliman Y Alomar
  • Zinab Abd-Elhady Ali
  • Sawsan A Zaitone
  • Mona K E Qushawy
  • Molecules.2020 Jul;25(14). E3230. doi: 10.3390/molecules25143230.Epub 2020-07-15.

同種造血幹細胞移植後に多発性硬化症様の再発性再発性脳脊髄炎を発症した1例と発表された文献のレビュー

A Case of Multiple Sclerosis-Like Relapsing Remitting Encephalomyelitis Following Allogeneic Hematopoietic Stem Cell Transplantation and a Review of the Published Literature.
  • Joyutpal Das
  • Atta Gill
  • Christine Lo
  • Natalie Chan-Lam
  • Siân Price
  • Stephen B Wharton
  • Helen Jessop
  • Basil Sharrack
  • John A Snowden
  • Front Immunol.2020;11:668. doi: 10.3389/fimmu.2020.00668.Epub 2020-05-05.

インフルエンザに感染すると、内在性ビフィドバクテリウム・アニマリスの腸内集団が拡大し、マウスを感染から保護します

Influenza infection elicits an expansion of gut population of endogenous Bifidobacterium animalis which protects mice against infection.
  • Qiang Zhang
  • Jin Hu
  • Jia-Wu Feng
  • Xiao-Tong Hu
  • Ting Wang
  • Wen-Xiao Gong
  • Kun Huang
  • Yi-Xiong Guo
  • Zhong Zou
  • Xian Lin
  • Run Zhou
  • Yu-Qi Yuan
  • An-Ding Zhang
  • Hong Wei
  • Gang Cao
  • Chen Liu
  • Ling-Ling Chen
  • Mei-Lin Jin
  • Genome Biol..2020 04;21(1):99. 10.1186/s13059-020-02007-1. doi: 10.1186/s13059-020-02007-1.Epub 2020-04-28.

2型糖尿病治療のための新規腎ナトリウム依存性グルコースコトランスポーター2(SGLT2)阻害剤としての6-デオキシO-スピロケタールC-アリルグルコシドの設計、合成、生物学的評価

Design, synthesis and biological evaluation of 6-deoxy O-spiroketal C-arylglucosides as novel renal sodium-dependent glucose cotransporter 2 (SGLT2) inhibitors for the treatment of type 2 diabetes.
  • Yibing Wang
  • Yang Lou
  • Jiang Wang
  • Dan Li
  • Hui Chen
  • Tiannan Zheng
  • Chunmei Xia
  • Xiaohan Song
  • Tiancheng Dong
  • Jingya Li
  • Jia Li
  • Hong Liu
  • Eur J Med Chem.2019 Oct;180:398-416. S0223-5234(19)30653-1. doi: 10.1016/j.ejmech.2019.07.032.Epub 2019-07-10.

Thermomyces lanuginosus由来リパーゼの新しいキトサンベースのヘテロ機能性支持体上での固定化の改善。混合イオン交換と疎水性相互作用

Improved immobilization of lipase from Thermomyces lanuginosus on a new chitosan-based heterofunctional support: Mixed ion exchange plus hydrophobic interactions.
  • Nicole S Okura
  • Guilherme J Sabi
  • Marcela C Crivellenti
  • Raphael A B Gomes
  • Roberto Fernandez-Lafuente
  • Adriano A Mendes
  • Int. J. Biol. Macromol..2020 Jul;163:550-561. S0141-8130(20)33766-1. doi: 10.1016/j.ijbiomac.2020.07.021.Epub 2020-07-06.

記述輸入された重症マラリア原虫の成人における急性呼吸窮迫症候群(ARDS):ポルトガルの第三療養病院における10年間の研究

Descriptive Acute Respiratory Distress Syndrome (ARDS) in adults with imported severe Plasmodium falciparum malaria: A 10 year-study in a Portuguese tertiary care hospital.
  • Luísa Graça
  • Isabel Gomes Abreu
  • Ana Sofia Santos
  • Luís Graça
  • Paulo Figueiredo Dias
  • Maria Lurdes Santos
  • PLoS ONE.2020;15(7):e0235437. PONE-D-20-02362. doi: 10.1371/journal.pone.0235437.Epub 2020-07-09.

限局性腎腫瘤に対する腎部分切除術後の周術期成績および手術マージンに及ぼす切除術の影響。プロスペクティブな多施設共同研究

Impact of Resection Technique on Perioperative Outcomes and Surgical Margins after Partial Nephrectomy for Localized Renal Masses: A Prospective Multicenter Study.
  • Andrea Minervini
  • Riccardo Campi
  • Brian R Lane
  • Ottavio De Cobelli
  • Francesco Sanguedolce
  • Georgios Hatzichristodoulou
  • Alessandro Antonelli
  • Sabrina Noyes
  • Andrea Mari
  • Oscar Rodriguez-Faba
  • Frank X Keeley
  • Johan Langenhuijsen
  • Gennaro Musi
  • Tobias Klatte
  • Marco Roscigno
  • Bulent Akdogan
  • Maria Furlan
  • Nihat Karakoyunlu
  • Martin Marszalek
  • Umberto Capitanio
  • Alessandro Volpe
  • Sabine Brookman-May
  • Jürgen E Gschwend
  • Marc C Smaldone
  • Robert G Uzzo
  • Marco Carini
  • Alexander Kutikov
  • J. Urol..2020 03;203(3):496-504. doi: 10.1097/JU.0000000000000591.Epub 2019-10-14.

TRPV1チャネルの活性化は、ポッドサイトにおける小胞体とミトコンドリアの接触を阻害することにより、糖尿病性腎症に拮抗する

Activation of TRPV1 channel antagonizes diabetic nephropathy through inhibiting endoplasmic reticulum-mitochondria contact in podocytes.
  • Xiao Wei
  • Xing Wei
  • Zongshi Lu
  • Li Li
  • Yingru Hu
  • Fang Sun
  • Yanli Jiang
  • Huan Ma
  • Hongting Zheng
  • Gangyi Yang
  • Daoyan Liu
  • Peng Gao
  • Zhiming Zhu
  • Metab. Clin. Exp..2020 04;105:154182. S0026-0495(20)30046-9. doi: 10.1016/j.metabol.2020.154182.Epub 2020-02-13.

非侵襲的な線維化マーカーであるFibrosis-4指数は、大腸がん肝転移に対する肝切除術後の生存率を予測する

Fibrosis-4 Index, a Noninvasive Fibrosis Marker, Predicts Survival Outcomes After Hepatectomy for Colorectal Cancer Liver Metastases.
  • Takahiko Akiyama
  • Yuji Miyamoto
  • Katsunori Imai
  • Yoichi Yamashita
  • Daichi Nomoto
  • Nobuya Daitoku
  • Yuki Sakamoto
  • Yuki Kiyozumi
  • Ryuma Tokunaga
  • Kojiro Eto
  • Kazuto Harada
  • Yukiharu Hiyoshi
  • Masaaki Iwatsuki
  • Yohei Nagai
  • Shiro Iwagami
  • Yoshifumi Baba
  • Naoya Yoshida
  • Hideo Baba
  • Ann. Surg. Oncol..2020 Jul;10.1245/s10434-020-08828-5. doi: 10.1245/s10434-020-08828-5.Epub 2020-07-09.

チロシンキナーゼ阻害薬は、転移性胃腸間質腫瘍患者の生存成績を有意に改善した:多施設コホート研究

Tyrosine kinase inhibitors significantly improved survival outcomes in patients with metastatic gastrointestinal stromal tumour: a multi-institutional cohort study.
  • A Deruchie Tan
  • K Willemsma
  • A MacNeill
  • K DeVries
  • A Srikanthan
  • C McGahan
  • T Hamilton
  • H Li
  • C D Blanke
  • C E Simmons
  • Curr Oncol.2020 Jun;27(3):e276-e282. conc-27-e276. doi: 10.3747/co.27.5869.Epub 2020-06-01.

間葉系上皮性卵巣癌細胞におけるLY75の抑制は、同所性異種移植マウスモデルにおいて、腫瘍の発生、広がりおよび治療抵抗性の向上と関連した安定なハイブリッドEOC細胞表現型を生成する

LY75 Suppression in Mesenchymal Epithelial Ovarian Cancer Cells Generates a Stable Hybrid EOC Cellular Phenotype, Associated with Enhanced Tumor Initiation, Spreading and Resistance to Treatment in Orthotopic Xenograft Mouse Model.
  • Sadia Mehdi
  • Elizabeth Macdonald
  • Kristianne Galpin
  • David A Landry
  • Galaxia Rodriguez
  • Barbara Vanderhyden
  • Dimcho Bachvarov
  • Int J Mol Sci.2020 Jul;21(14). E4992. doi: 10.3390/ijms21144992.Epub 2020-07-15.

Dientamoeba fragilis治療においてパロマイシンはメトロニダゾールよりも優れている

Paromomycin is superior to metronidazole in Dientamoeba fragilis treatment.
  • Ander Burgaña
  • Rosa Abellana
  • Stanislav Zlatanov Yordanov
  • Rabee Kazan
  • A Mauricio Pérez Ortiz
  • Cristina Castillo Ramos
  • Christian Garavito Hernández
  • Miriam Molina Rivero
  • Alessandra Queiroga Gonçalves
  • Emma Padilla
  • Josefa Pérez
  • Roger García-Puig
  • Tomas M Perez-Porcuna
  • Int J Parasitol Drugs Drug Resist.2019 12;11:95-100. S2211-3207(19)30140-X. doi: 10.1016/j.ijpddr.2019.10.005.Epub 2019-11-11.

アザチオプリン、塩酸クロニジン、クロピドグレル二硫酸塩、塩酸エタンブトール、グリセオフルビン、塩酸ヒドラジン、ニトロフラントインおよびチオグアニン経口懸濁液の安定性

Stability of Azathioprine, Clonidine Hydrochloride, Clopidogrel Bisulfate, Ethambutol Hydrochloride, Griseofulvin, Hydralazine Hydrochloride, Nitrofurantoin, and Thioguanine Oral Suspensions Compounded with SyrSpend SF pH4.
  • Hudson Polonini
  • Sharlene Loures da Silva
  • Carolina Neves Cunha
  • Anderson de Oliveira Ferreira
  • Korina Anagnostou
  • Eli Dijkers
  • Int J Pharm Compd.2020 May-Jun;24(3):252-262.

乳酸脱水素酵素と軽度のCOVID-19患者の悪化感受性:多施設非ステッド症例対照研究

Lactate dehydrogenase and susceptibility to deterioration of mild COVID-19 patients: a multicenter nested case-control study.
  • Jichan Shi
  • Yang Li
  • Xian Zhou
  • Qiran Zhang
  • Xinchun Ye
  • Zhengxing Wu
  • Xiangao Jiang
  • Hongying Yu
  • Lingyun Shao
  • Jing-Wen Ai
  • Haocheng Zhang
  • Bin Xu
  • Feng Sun
  • Wenhong Zhang
  • BMC Med.2020 06;18(1):168. 10.1186/s12916-020-01633-7. doi: 10.1186/s12916-020-01633-7.Epub 2020-06-03.

生理活性キナクリンと銀のハイブリッドナノ粒子による口腔癌幹細胞の細胞毒性と血管新生阻害の強化」の訂正。癌細胞の細胞毒性の増強:塩基切開修復カスケードの示唆」の訂正

Correction to "Enhancement of Cytotoxicity and Inhibition of Angiogenesis in Oral Cancer Stem Cells by a Hybrid Nanoparticle of Bioactive Quinacrine and Silver: Implication of Base Excision Repair Cascade".
  • Shakti Ranjan Satapathy
  • Sumit Siddharth
  • Dipon Das
  • Anmada Nayak
  • Chanakya Nath Kundu
  • Mol. Pharm..2020 Jul;doi: 10.1021/acs.molpharmaceut.0c00706.Epub 2020-07-17.

ホスホグルコムターゼ 1 欠損症(PGM1-CDG)の国際的コンセンサスガイドライン:診断、フォローアップおよび管理

International consensus guidelines for phosphoglucomutase 1 deficiency (PGM1-CDG): diagnosis, follow-up and management.
  • Ruqaiah Altassan
  • Silvia Radenkovic
  • Andrew C Edmondson
  • Rita Barone
  • Sandra Brasil
  • Anna Cechova
  • David Coman
  • Sarah Donoghue
  • Kristina Falkenstein
  • Vanessa Ferreira
  • Carlos Ferreira
  • Agata Fiumara
  • Rita Francsico
  • Hudson Freeze
  • Stephanie Grunewald
  • Tomas Honzik
  • Jaak Jaeken
  • Donna Krasnewich
  • Christina Lam
  • Joy Lee
  • Dirk Lefeber
  • Dorinda Marques-da-Silva
  • Carlota Pascoal
  • Dulce Quelhas
  • Kimiyo M Raymond
  • Daisy Rymen
  • Malgorzata Seroczynska
  • Mercedes Serrano
  • Jolanta Sykut-Cegielska
  • Christian Thiel
  • Frederic Tort
  • Mari-Anne Vals
  • Paula Videira
  • Nicol Voermans
  • Peter Witters
  • Eva Morava
  • J. Inherit. Metab. Dis..2020 Jul;doi: 10.1002/jimd.12286.Epub 2020-07-18.

経皮的経皮的経皮的血管形成術後の表在性大腿動脈裂孔の評価:カラーコードされたsummation画像と単色デジタルサブトラクション血管造影

Evaluation of superficial femoral artery-lesions after percutaneous transluminal angioplasty: color-coded summation images vs. monochromatic digital subtraction angiography.
  • Anne Marie Augustin
  • Irina Thein
  • Nicole Rickert
  • Thorsten Klink
  • Thorsten Alexander Bley
  • Ralph Kickuth
  • BMC Med Imaging.2020 Jun;20(1):67. 10.1186/s12880-020-00468-1. doi: 10.1186/s12880-020-00468-1.Epub 2020-06-18.

四面体DNAナノ構造体をベースとした多機能複合体の設計、作製、およびドラッグデリバリーおよび生物医学的治療への応用

Design, fabrication and applications of tetrahedral DNA nanostructure-based multifunctional complexes in drug delivery and biomedical treatment.
  • Tao Zhang
  • Taoran Tian
  • Ronghui Zhou
  • Songhang Li
  • Wenjuan Ma
  • Yuxin Zhang
  • Nanxin Liu
  • Sirong Shi
  • Qianshun Li
  • Xueping Xie
  • Yichen Ge
  • Mengting Liu
  • Qi Zhang
  • Shiyu Lin
  • Xiaoxiao Cai
  • Yunfeng Lin
  • Nat Protoc.2020 Jul;10.1038/s41596-020-0355-z. doi: 10.1038/s41596-020-0355-z.Epub 2020-07-15.

ジンバブエにおける多剤耐性およびリファンピシン耐性結核の治療成績:2010年から2015年の間に治療を開始した患者のコホート解析

Treatment outcomes of multi drug resistant and rifampicin resistant Tuberculosis in Zimbabwe: A cohort analysis of patients initiated on treatment during 2010 to 2015.
  • Ronnie Matambo
  • Kudakwashe C Takarinda
  • Pruthu Thekkur
  • Charles Sandy
  • Sungano Mharakurwa
  • Talent Makoni
  • Ronald Ncube
  • Kelvin Charambira
  • Christopher Zishiri
  • Mkhokheli Ngwenya
  • Saziso Nyathi
  • Albert Chiteka
  • Elliot Chikaka
  • Shungu Mutero-Munyati
  • PLoS ONE.2020;15(4):e0230848. PONE-D-19-16150. doi: 10.1371/journal.pone.0230848.Epub 2020-04-30.

多剤耐性結核患者における体格指数の変化のプロファイルの違い:レトロスペクティブコホート研究

Different profiles of body mass index variation among patients with multidrug-resistant tuberculosis: a retrospective cohort study.
  • Alhassane Diallo
  • Boubacar Djelo Diallo
  • Lansana Mady Camara
  • Lucrèce Ahouéfa Nadège Kounoudji
  • Boubacar Bah
  • Fulgence N'Zabintawali
  • Miguel Carlos-Bolumbu
  • Mamadou Hassimiou Diallo
  • Oumou Younoussa Sow
  • BMC Infect. Dis..2020 Apr;20(1):315. 10.1186/s12879-020-05028-0. doi: 10.1186/s12879-020-05028-0.Epub 2020-04-28.

RECIST 1.1、irRC、iRECIST基準に基づく半自動ソフトウェアによる免疫療法の奏効評価:主観的評価との比較

Response evaluation for immunotherapy through semi-automatic software based on RECIST 1.1, irRC, and iRECIST criteria: comparison with subjective assessment.
  • Ying-Chieh Lai
  • Wen-Cheng Chang
  • Chun-Bing Chen
  • Chi-Liang Wang
  • Yu-Fen Lin
  • Ming-Mo Ho
  • Chi-Yuan Cheng
  • Pei-Wei Huang
  • Chao-Wei Hsu
  • Gigin Lin
  • Acta Radiol.2020 Jul;61(7):983-991. doi: 10.1177/0284185119887588.Epub 2019-11-18.

高齢の非小細胞肺がん患者におけるプラチナ製剤ベースの化学療法。現実の世界で何を期待すべきか

Platinum-Based Chemotherapy in Older Patients with Non-Small Cell Lung Cancer: What to Expect in the Real World.
  • Giacomo Pelizzari
  • Francesco Cortiula
  • Marco Giavarra
  • Michele Bartoletti
  • Camilla Lisanti
  • Vanessa Buoro
  • Monica Cattaneo
  • Ciro Rossetto
  • Simona Rizzato
  • Fabio Puglisi
  • Marianna Macerelli
  • Gianpiero Fasola
  • Alessandro Follador
  • Drugs Aging.2020 Jul;10.1007/s40266-020-00785-8. doi: 10.1007/s40266-020-00785-8.Epub 2020-07-17.

発達期Wntシグナル伝達経路エフェクターβ-カテニン/TCFは、脂質代謝を調節する性ホルモンエストラジオールの肝機能を媒介している

The developmental Wnt signaling pathway effector β-catenin/TCF mediates hepatic functions of the sex hormone estradiol in regulating lipid metabolism.
  • Lili Tian
  • Weijuan Shao
  • Wilfred Ip
  • Zhuolun Song
  • Yasaman Badakhshi
  • Tianru Jin
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新興汚染物質除去のための代替バイオプロセスに関するレビュー

A review on alternative bioprocesses for removal of emerging contaminants.
  • Aline Viancelli
  • William Michelon
  • Paula Rogovski
  • Rafael Dorighello Cadamuro
  • Estêvão Brasiliense de Souza
  • Gislaine Fongaro
  • Aline Frumi Camargo
  • Fábio Sptiza Stefanski
  • Bruno Venturin
  • Thamarys Scapini
  • Charline Bonatto
  • Karina Paula Preczeski
  • Natalia Klanovicz
  • Débora de Oliveira
  • Helen Treichel
  • Bioprocess Biosyst Eng.2020 Jul;10.1007/s00449-020-02410-9. doi: 10.1007/s00449-020-02410-9.Epub 2020-07-17.

PTSD治療のためのMDMA支援心理療法の長期追跡調査結果:6つの第2相試験の縦断的プール解析

Long-term follow-up outcomes of MDMA-assisted psychotherapy for treatment of PTSD: a longitudinal pooled analysis of six phase 2 trials.
  • Lisa Jerome
  • Allison A Feduccia
  • Julie B Wang
  • Scott Hamilton
  • Berra Yazar-Klosinski
  • Amy Emerson
  • Michael C Mithoefer
  • Rick Doblin
  • Psychopharmacology (Berl.).2020 Aug;237(8):2485-2497. 10.1007/s00213-020-05548-2. doi: 10.1007/s00213-020-05548-2.Epub 2020-06-04.

ヨーロッパ産ガラスウナギ(Anguilla anguilla)の行動とエネルギー関連遺伝子の転写反応にメチル水銀の新たな知見を得た

New insights into methylmercury induced behavioral and energy-related gene transcriptional responses in European glass eel (Anguilla anguilla).
  • Hengtong Liu
  • Amaia Lamarins
  • Jacques Labonne
  • Mathilde Monperrus
  • Pascale Coste
  • Emmanuel Huchet
  • Jacques Rives
  • Iban Seiliez
  • Valérie Bolliet
  • Chemosphere.2020 Sep;255:127020. S0045-6535(20)31213-3. doi: 10.1016/j.chemosphere.2020.127020.Epub 2020-05-10.

新生児のセボフルラン曝露は、その後のセボフルラン曝露の副作用に対する脆弱性の窓を広げ、デシタビン感受性機序を介して海馬の形態を変化させる

Neonatal exposure to sevoflurane expands the window of vulnerability to adverse effects of subsequent exposure to sevoflurane and alters hippocampal morphology via decitabine-sensitive mechanisms.
  • Yunan Lin
  • Lei Lei
  • Ling-Sha Ju
  • Ning Xu
  • Timothy E Morey
  • Nikolaus Gravenstein
  • Jianjun Yang
  • Anatoly E Martynyuk
  • Neurosci. Lett..2020 Jul;735:135240. S0304-3940(20)30510-3. doi: 10.1016/j.neulet.2020.135240.Epub 2020-07-07.

早期ホルモン陽性乳癌の女性における手術選択とその後の患者報告満足度の転帰との関係における人種差

Racial differences in the relationship between surgical choice and subsequent patient-reported satisfaction outcomes among women with early-stage hormone-positive breast cancer.
  • Prudvi Arabandi
  • Alexander N Slade
  • Arnethea L Sutton
  • Kandace P McGuire
  • Vanessa Sheppard
  • Breast Cancer Res. Treat..2020 Jul;10.1007/s10549-020-05784-2. doi: 10.1007/s10549-020-05784-2.Epub 2020-07-16.

p32/C1QBPは、ミトコンドリアの機能不全やアポトーシスに関連するミトコンドリアの連結性を維持するために、OMA1依存性のタンパク質分解処理を制御しています

p32/C1QBP regulates OMA1-dependent proteolytic processing of OPA1 to maintain mitochondrial connectivity related to mitochondrial dysfunction and apoptosis.
  • Solhee Noh
  • Sophors Phorl
  • Rema Naskar
  • Kakada Oeum
  • Yuri Seo
  • Eunjung Kim
  • Hee-Seok Kweon
  • Joo-Yong Lee
  • Sci Rep.2020 Jun;10(1):10618. 10.1038/s41598-020-67457-w. doi: 10.1038/s41598-020-67457-w.Epub 2020-06-30.

手術不能な慢性血栓塞栓性肺高血圧症に対するバルーン肺血管形成術:英国での経験

Balloon pulmonary angioplasty for inoperable chronic thromboembolic pulmonary hypertension: the UK experience.
  • Stephen P Hoole
  • John G Coghlan
  • John E Cannon
  • Dolores Taboada
  • Mark Toshner
  • Karen Sheares
  • Andrew John Fletcher
  • Guillermo Martinez
  • Alessandro Ruggiero
  • Nicholas Screaton
  • David Jenkins
  • Joanna Pepke-Zaba
  • Open Heart.2020;7(1):e001144. openhrt-2019-001144. doi: 10.1136/openhrt-2019-001144.Epub 2020-02-27.

胚性幹細胞由来心筋細胞における成熟心室サブタイプの優位性が生体内で増加している

Increased predominance of the matured ventricular subtype in embryonic stem cell-derived cardiomyocytes in vivo.
  • Hajime Ichimura
  • Shin Kadota
  • Toshihide Kashihara
  • Mitsuhiko Yamada
  • Kuniaki Ito
  • Hideki Kobayashi
  • Yuki Tanaka
  • Naoko Shiba
  • Shinichiro Chuma
  • Shugo Tohyama
  • Tatsuichiro Seto
  • Kenji Okada
  • Koichiro Kuwahara
  • Yuji Shiba
  • Sci Rep.2020 Jul;10(1):11883. 10.1038/s41598-020-68373-9. doi: 10.1038/s41598-020-68373-9.Epub 2020-07-17.

資源が限られた環境下で、初期の臨床的特徴と検査的特徴を用いて、重症化リスクの高いデング熱患者を同定すること

Identification of dengue patients with high risk of severe disease, using early clinical and laboratory features, in a resource-limited setting.
  • Madunil A Niriella
  • Isurujith K Liyanage
  • Arundathi Udeshika
  • Kasun V Liyanapathirana
  • Arjuna P De Silva
  • Hithnadura J de Silva
  • Arch. Virol..2020 Jul;10.1007/s00705-020-04720-5. doi: 10.1007/s00705-020-04720-5.Epub 2020-07-02.

ジカの時代における希望と信頼:ブラジルにおける流行の最前線にいる介護者と医療従事者の見解

Hope and trust in times of Zika: the views of caregivers and healthcare workers at the forefront of the epidemic in Brazil.
  • Clarissa Simas
  • Loveday Penn-Kekana
  • Hannah Kuper
  • Tereza Maciel Lyra
  • Maria Elisabeth Lopes Moreira
  • Maria do Socorro Veloso de Albuquerque
  • Thália Velho Barreto de Araújo
  • Ana Paula Lopes de Melo
  • Corina Helena Figueira Mendes
  • Martha Cristina Nunes Moreira
  • Marcos Antonio Ferreira do Nascimento
  • Camila Pimentel
  • Marcia Pinto
  • Sandra Valongueiro
  • Heidi Larson
  • Health Policy Plan.2020 Jul;czaa042. doi: 10.1093/heapol/czaa042.Epub 2020-07-18.

ミエリンオリゴデンドロサイト糖鎖抗体関連視神経炎の臨床的特徴の白人とアジア系人種間での違い

Differences in Clinical Features of Myelin Oligodendrocyte Glycoprotein Antibody-Associated Optic Neuritis in White and Asian Race.
  • Tanyatuth Padungkiatsagul
  • John J Chen
  • Panitha Jindahra
  • Tetsuya Akaishi
  • Toshiyuki Takahashi
  • Ichiro Nakashima
  • Takayuki Takeshita
  • Heather E Moss
  • Am. J. Ophthalmol..2020 Jul;S0002-9394(20)30359-7. doi: 10.1016/j.ajo.2020.07.008.Epub 2020-07-15.

PARP酵素のターゲットエンゲージメントを研究するためのインビトロおよび細胞プローブ

In Vitro and Cellular Probes to Study PARP Enzyme Target Engagement.
  • Tim J Wigle
  • Danielle J Blackwell
  • Laurie B Schenkel
  • Yue Ren
  • W David Church
  • Hetvi J Desai
  • Kerren K Swinger
  • Andrew G Santospago
  • Christina R Majer
  • Alvin Z Lu
  • Mario Niepel
  • Nicholas R Perl
  • Melissa M Vasbinder
  • Heike Keilhack
  • Kevin W Kuntz
  • Cell Chem Biol.2020 Jul;27(7):877-887.e14. S2451-9456(20)30232-4. doi: 10.1016/j.chembiol.2020.06.009.

転移性去勢抵抗性前立腺がんの男性における双極性アンドロゲン療法の多施設共同オープンラベル第II相試験(RESTORE)。アビラテロン投与後とエンザルツアミド投与後のコホートの比較

A Multicohort Open-label Phase II Trial of Bipolar Androgen Therapy in Men with Metastatic Castration-resistant Prostate Cancer (RESTORE): A Comparison of Post-abiraterone Versus Post-enzalutamide Cohorts.
  • Mark C Markowski
  • Hao Wang
  • Rana Sullivan
  • Irina Rifkind
  • Victoria Sinibaldi
  • Michael T Schweizer
  • Benjamin A Teply
  • Nduku Ngomba
  • Wei Fu
  • Michael A Carducci
  • Channing J Paller
  • Catherine H Marshall
  • Mario A Eisenberger
  • Jun Luo
  • Emmanuel S Antonarakis
  • Samuel R Denmeade
  • Eur. Urol..2020 Jul;S0302-2838(20)30471-1. doi: 10.1016/j.eururo.2020.06.042.Epub 2020-07-02.

COVID-19感染症における止血プロファイル

Hemostasis profile in COVID-19 infection.
  • Fernando Barroso Duarte
  • Rosângela Pinheiro Gonçalves Machado
  • Romélia Pinheiro Gonçalves Lemes
  • Isabella Araújo Duarte
  • Beatrice Araújo Duarte
  • Clarissa Maria Gonçalves Machado
  • João Vitor Araújo Duarte
  • Samuel Gonçalves Machado da Rocha
  • Anna Thawanny Gadelha Moura
  • Rosangela de Albuquerque Ribeiro Rodrigues Holanda
  • Rev Assoc Med Bras (1992).2020 05;66(5):571-572. S0104-42302020000500571. doi: 10.1590/1806-9282.66.5.571.Epub 2020-07-03.

ベトナムの気候変動と健康の脆弱性と適応評価、2018年

Vietnam Climate Change and Health Vulnerability and Adaptation Assessment, 2018.
  • Tran Thi Tuyet Hanh
  • Le Thi Thanh Huong
  • Nguyen Thi Lien Huong
  • Tran Nu Quy Linh
  • Nguyen Huu Quyen
  • Nguyen Thi Trang Nhung
  • Kristie Ebi
  • Nguyen Dinh Cuong
  • Ha Van Nhu
  • Tran Mai Kien
  • Simon Hales
  • Do Manh Cuong
  • Nguyen Thi Thi Tho
  • Luu Quoc Toan
  • Nguyen Ngoc Bich
  • Hoang Van Minh
  • Environ Health Insights.2020;14:1178630220924658. 10.1177_1178630220924658. doi: 10.1177/1178630220924658.Epub 2020-06-22.

水でろ過した赤外線Aおよび可視光(wIRA/VIS)治療は、包接結膜炎のモルモットモデルにおけるクラミジア・キャビア誘発性眼炎症および感染負荷を減少させる

Water-filtered Infrared A and visible light (wIRA/VIS) treatment reduces Chlamydia caviae-induced ocular inflammation and infectious load in a Guinea pig model of inclusion conjunctivitis.
  • Aleksandra Inic-Kanada
  • Marijana Stojanovic
  • Radmila Miljkovic
  • Elisabeth Stein
  • Ana Filipovic
  • Antonia Frohns
  • Nadja Zöller
  • Jasmin Kuratli
  • Talin Barisani-Asenbauer
  • Nicole Borel
  • J. Photochem. Photobiol. B, Biol..2020 Jul;209:111953. S1011-1344(20)30403-6. doi: 10.1016/j.jphotobiol.2020.111953.Epub 2020-07-05.

東南アジアの低中所得国の動物病院が直面するバイオセーフティとバイオセキュリティの課題。タイの事例研究

Biosafety and Biosecurity Challenges Facing Veterinary Diagnostic Laboratories in Lower-Middle Income Countries in Southeast Asia: A Case Study of Thailand.
  • Jarunee Siengsanan-Lamont
  • Somjai Kamolsiripichaiporn
  • Soiratchaneekorn Ruanchaimun
  • Tuangthong Patchimasiri
  • Banjong Jongrakwattana
  • Stuart D Blacksell
  • Appl Biosaf.2019 Dec;24(4):220-230. 10.1177_1535676019869771. doi: 10.1177/1535676019869771.Epub 2019-08-19.

リポ多糖類誘発性急性肺障害は、マウスモデルにおける微小管形成センター(RanBPM)分子発現とミトコンドリア介在性アポトーシスシグナル伝達経路のRan-Binding Proteinの増加と関連している

Lipopolysaccharide-Induced Acute Lung Injury Is Associated with Increased Ran-Binding Protein in Microtubule-Organizing Center (RanBPM) Molecule Expression and Mitochondria-Mediated Apoptosis Signaling Pathway in a Mouse Model.
  • Xiaojing Lv
  • Xiaomin Lu
  • Jiping Zhu
  • Qian Wang
  • Med. Sci. Monit..2020 Jul;26:e923172. 923172. doi: 10.12659/MSM.923172.Epub 2020-07-18.

リツキシマブによる維持療法中に多発性血管炎を伴う肉芽腫症とインフルエンザ肺炎を併発した症例で、偽陰性検査を繰り返した結果、COVID-19の診断が遅れた

Repeated false-negative tests delayed diagnosis of COVID-19 in a case with granulomatosis with polyangiitis under maintenance therapy with rituximab and concomitant influenza pneumonia.
  • Samy Hakroush
  • Jonas Franz
  • Jörg Larsen
  • Peter Korsten
  • Martin Sebastian Winkler
  • Björn Tampe
  • Ann. Rheum. Dis..2020 Jul;annrheumdis-2020-218491. doi: 10.1136/annrheumdis-2020-218491.Epub 2020-07-15.

α2Aアドレナリン受容体欠損症は、急性呼吸窮迫症候群におけるノルエピネフリンレベルの上昇と肺胞マクロファージ活性化の阻害により、リポ多糖類誘発性肺障害を減衰させる

Alpha2A-adrenoceptor deficiency attenuates lipopolysaccharide-induced lung injury by increasing norepinephrine levels and inhibiting alveolar macrophage activation in acute respiratory distress syndrome.
  • Zhukai Cong
  • Dan Li
  • Xiangpeng Lv
  • Cui Yang
  • Qiang Zhang
  • Changyi Wu
  • Zongyu Wang
  • Xi Zhu
  • Clin. Sci..2020 Jul;CS20200586. doi: 10.1042/CS20200586.Epub 2020-07-09.

死細胞のファゴサイトーシスの障害によって引き起こされる組織損傷。肺炎におけるγδT細胞の病因に関与するこれまでにない副作用

Tissue Damage Caused by Impaired Phagocytosis of Dead Cells: A Previously Unrecognized Adverse Effect Contributing to the Pathogenesis of γδ T Cells in Pneumonia.
  • Chiaki Kajiwara
  • Soichiro Kimura
  • Yuriko Tanaka
  • Yoshikiyo Akasaka
  • Yoshikazu Ishii
  • Kazuhiro Tateda
  • Immunohorizons.2020 Jul;4(7):402-414. 4/7/402. doi: 10.4049/immunohorizons.2000054.Epub 2020-07-14.

鉄の鎖のUBC-HCT:アル・マルキらによる「鉄の過負荷はDelayed EngraftmentとAssociated with Delayed Engraftment and Increased Non-Relapse Mortality in Recipients of Umbilical Cord Blood Hematopoietic Cell Transplantation」へのコメント 2020

Chains of Iron in UBC-HCT: Comment on "Iron Overload is Associated with Delayed Engraftment and Increased Non-Relapse Mortality in Recipients of Umbilical Cord Blood Hematopoietic Cell Transplantation" by Al Malki et al. 2020.
  • Mary Ann Knovich
  • Biol. Blood Marrow Transplant..2020 Jul;S1083-8791(20)30441-9. doi: 10.1016/j.bbmt.2020.07.012.Epub 2020-07-15.

薬物ナイーブ」パーキンソン病患者におけるBDNFレベルと黒質変性。I-123-FP-CIT SPECTを用いた"in vivo"研究

BDNF levels and nigrostriatal degeneration in "drug naïve" Parkinson's disease patients. An "in vivo" study using I-123-FP-CIT SPECT.
  • J Hernández-Vara
  • N Sáez-Francàs
  • C Lorenzo-Bosquet
  • M Corominas-Roso
  • G Cuberas-Borròs
  • S Lucas-Del Pozo
  • S Carter
  • M Armengol-Bellapart
  • J Castell-Conesa
  • Parkinsonism Relat. Disord..2020 Jul;78:31-35. S1353-8020(20)30214-5. doi: 10.1016/j.parkreldis.2020.06.037.Epub 2020-07-04.

蝸牛難聴および聴覚神経障害スペクトラム障害における強度の差を評価する客観的尺度としての音響変化複素数の有用性

Utility of Acoustic Change Complex as an Objective Tool to Evaluate Difference Limen for Intensity in Cochlear Hearing Loss and Auditory Neuropathy Spectrum Disorder.
  • Prawin Kumar
  • Himanshu Kumar Sanju
  • Reesha Oovattil Hussain
  • Mechiyanda Kaverappa Ganapathy
  • Niraj Kumar Singh
  • Am J Audiol.2020 Jul;:1-9. doi: 10.1044/2020_AJA-19-00084.Epub 2020-07-06.

ノルウェーの未就学児集団における精神衛生上の問題のスクリーニング。年齢および段階別質問票の検証。Social-emotional(ASQ:SE)

Screening for mental health problems in a Norwegian preschool population. A validation of the ages and stages questionnaire: Social-emotional (ASQ:SE).
  • Kenneth Stensen
  • Frode Stenseng
  • Stian Lydersen
  • Marianne Suzanne de Wolff
  • Jan Wallander
  • May Britt Drugli
  • Child Adolesc Ment Health.2018 Nov;23(4):368-375. doi: 10.1111/camh.12257.Epub 2018-01-25.

スリランカにおける鎌状赤血球症:臨床的・分子的基盤と疾患の重症度に関する未解明の疑問

Sickle cell disease in Sri Lanka: clinical and molecular basis and the unanswered questions about disease severity.
  • Thamal Darshana
  • Dayananda Bandara
  • Upul Nawarathne
  • Udaya de Silva
  • Yasinta Costa
  • Kalavitigoda Pushpakumara
  • Sumithra Pathirage
  • Seuwandi Basnayake
  • Chamila Epa
  • Pradeepa Dilrukshi
  • Maheshaka Wijayawardena
  • Angela A Anthony
  • Rexan Rodrigo
  • Aresha Manamperi
  • Frances Smith
  • Angela Allen
  • Stephan Menzel
  • David Rees
  • Anuja Premawardhena
  • Orphanet J Rare Dis.2020 Jul;15(1):177. 10.1186/s13023-020-01458-w. doi: 10.1186/s13023-020-01458-w.Epub 2020-07-06.