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日本語AIでPubMedを検索

日本語AIでPubMedを検索

PubMedの提供する医学論文データベースを日本語で検索できます。AI(Deep Learning)を活用した機械翻訳エンジンにより、精度高く日本語へ翻訳された論文をご参照いただけます。

みんなが読んでいる論文

Chemotherapy and Venetoclax in Elderly Acute Myeloid Leukemia Trial(CAVEAT)。修正集中化学療法とベネトグラックス併用の第Ib相用量漸増試験

Chemotherapy and Venetoclax in Elderly Acute Myeloid Leukemia Trial (CAVEAT): A Phase Ib Dose-Escalation Study of Venetoclax Combined With Modified Intensive Chemotherapy.
  • Chong Chyn Chua
  • Andrew W Roberts
  • John Reynolds
  • Chun Yew Fong
  • Stephen B Ting
  • Jessica M Salmon
  • Sarah MacRaild
  • Adam Ivey
  • Ing Soo Tiong
  • Shaun Fleming
  • Fiona C Brown
  • Sun Loo
  • Ian J Majewski
  • Stefan K Bohlander
  • Andrew H Wei
  • J. Clin. Oncol..2020 Jul;:JCO2000572. doi: 10.1200/JCO.20.00572.Epub 2020-07-20.

YBX1ホモログYPSは、5-メチルシトシンRNAを優先的に認識することで卵巣生殖細胞幹細胞の発生を促進する

YBX1 homolog YPS promotes ovarian germ line stem cell development by preferentially recognizing 5-methylcytosine RNAs.
  • Fan Zou
  • Renjun Tu
  • Bo Duan
  • Zhenlin Yang
  • Zhaohua Ping
  • Xiaoqing Song
  • Shiyuan Chen
  • Andrew Price
  • Hua Li
  • Allison Scott
  • Anoja Perera
  • Sisi Li
  • Ting Xie
  • Proc. Natl. Acad. Sci. U.S.A..2020 02;117(7):3603-3609. 1910862117. doi: 10.1073/pnas.1910862117.Epub 2020-02-03.

ヒト免疫不全ウイルスおよびC型肝炎ウイルスに感染した患者における動脈硬化性心血管系イベント

Atherosclerotic Cardiovascular Events in Patients Infected With Human Immunodeficiency Virus and Hepatitis C Virus.
  • Boun Kim Tan
  • Mathieu Chalouni
  • Dominique Salmon Ceron
  • Alexandre Cinaud
  • Laure Esterle
  • Marc Arthur Loko
  • Christine Katlama
  • Isabelle Poizot-Martin
  • Didier Neau
  • Julie Chas
  • Philippe Morlat
  • Eric Rosenthal
  • Karine Lacombe
  • Alissa Naqvi
  • Karl Barange
  • Olivier Bouchaud
  • Anne Gervais
  • Caroline Lascoux-Combe
  • Daniel Garipuy
  • Laurent Alric
  • Cécile Goujard
  • Patrick Miailhes
  • Hugues Aumaitre
  • Claudine Duvivier
  • Anne Simon
  • Jose-Luis Lopez-Zaragoza
  • David Zucman
  • François Raffi
  • Estibaliz Lazaro
  • David Rey
  • Lionel Piroth
  • François Boué
  • Camille Gilbert
  • Firouzé Bani-Sadr
  • François Dabis
  • Philippe Sogni
  • Linda Wittkop
  • Franck Boccara
  • Clin. Infect. Dis..2020 Jul;ciaa1014. doi: 10.1093/cid/ciaa1014.Epub 2020-07-20.

アペリンは、アペリン受容体、プロテインキナーゼA、細胞外シグナル制御キナーゼ1/2活性化を介して、ヒトトロフォブラストBeWo細胞による胎盤ホルモン分泌を減少させた

Apelin decreased placental hormoine secretion by human trophoblast BeWo cells via apelin receptor, protein kinase A and extracellular signal-regulated kinases 1/2 activation.
  • M Dawid
  • E Mlyczynska
  • P Kurowska
  • M Sierpowski
  • A Rak
  • J. Physiol. Pharmacol..2019 Dec;70(6). doi: 10.26402/jpp.2019.6.08.Epub 2020-02-19.

P21の組換え型は宿主の免疫応答を調節することで感染を制御している

The Recombinant Form of P21 Controls Infection by Modulating Host Immune Response.
  • Flávia Alves Martins
  • Marlus Alves Dos Santos
  • Júlia de Gouveia Santos
  • Aline Alves da Silva
  • Bruna Cristina Borges
  • Mylla Spirandelli da Costa
  • Paula Cristina Brígido Tavares
  • Samuel Cota Teixeira
  • Rebecca Tavares E Silva Brígido
  • Thaise Lara Teixeira
  • Cassiano Costa Rodrigues
  • Nadjania Saraiva de Lira Silva
  • Rayane Cristina de Oliveira
  • Laura Caroline de Faria
  • Marcela Rezende Lemes
  • Renata Graciele Zanon
  • Tatiana Carla Tomiosso
  • Juliana Reis Machado
  • Marcos Vinicius da Silva
  • Carlo José Freire Oliveira
  • Claudio Vieira da Silva
  • Front Immunol.2020;11:1010. doi: 10.3389/fimmu.2020.01010.Epub 2020-06-05.

イリ科植物のファイトケミカル組成とインビトロ生物学的活性.口腔内細菌バイオフィルムの抑制のための新たな生理活性成分の供給源

Phytochemical Composition and In Vitro Biological Activity of spp. (Iridaceae): A New Source of Bioactive Constituents for the Inhibition of Oral Bacterial Biofilms.
  • Lan Hoang
  • František Beneš
  • Marie Fenclová
  • Olga Kronusová
  • Viviana Švarcová
  • Kateřina Řehořová
  • Eva Baldassarre Švecová
  • Miroslav Vosátka
  • Jana Hajšlová
  • Petr Kaštánek
  • Jitka Viktorová
  • Tomáš Ruml
  • Antibiotics (Basel).2020 Jul;9(7). E403. doi: 10.3390/antibiotics9070403.Epub 2020-07-11.

2つの木材腐朽菌Ganoderma applanatumとLaetiporus sulphureusによるNSAIDsの新規コビマス分解。リグニン分解酵素の誘導、等温および速度論的研究

Novel cobiomass degradation of NSAIDs by two wood rot fungi, Ganoderma applanatum and Laetiporus sulphureus: Ligninolytic enzymes induction, isotherm and kinetic studies.
  • Paul Olusegun Bankole
  • Adedotun Adeyinka Adekunle
  • Byong-Hun Jeon
  • Sanjay Prabhu Govindwar
  • Ecotoxicol. Environ. Saf..2020 Jul;203:110997. S0147-6513(20)30836-8. doi: 10.1016/j.ecoenv.2020.110997.Epub 2020-07-16.

Alinity m HIV-1アッセイの性能の多施設臨床比較評価

Multicenter clinical comparative evaluation of Alinity m HIV-1 assay performance.
  • Patrick Braun
  • Allison Glass
  • Leana Maree
  • Maria Krügel
  • Monia Pacenti
  • Francesco Onelia
  • Rory Gunson
  • Emily Goldstein
  • Laura Martínez-García
  • Juan-Carlos Galán
  • Alba Vilas
  • Jodie D'costa
  • Rizmina Sameer
  • Robert Ehret
  • Heribert Knechten
  • Gudrun Naeth
  • Magali Bouvier-Alias
  • Natalia Marlowe
  • Michael J Palm
  • Ajith M Joseph
  • Jens Dhein
  • Birgit Reinhardt
  • Karin Pfeifer
  • Danijela Lucic
  • Martin Obermeier
  • J. Clin. Virol..2020 Jul;129:104530. S1386-6532(20)30272-9. doi: 10.1016/j.jcv.2020.104530.Epub 2020-07-03.

CTGリピート選択的化学スクリーニングにより、微小管阻害剤が有毒CUG RNAレベルの選択的調節因子として同定された

A CTG repeat-selective chemical screen identifies microtubule inhibitors as selective modulators of toxic CUG RNA levels.
  • Kaalak Reddy
  • Jana R Jenquin
  • Ona L McConnell
  • John D Cleary
  • Jared I Richardson
  • Belinda S Pinto
  • Maja C Haerle
  • Elizabeth Delgado
  • Lori Planco
  • Masayuki Nakamori
  • Eric T Wang
  • J Andrew Berglund
  • Proc. Natl. Acad. Sci. U.S.A..2019 10;116(42):20991-21000. 1901893116. doi: 10.1073/pnas.1901893116.Epub 2019-09-30.

SARS-CoV-2感染後の急性低運動性硬直症候群

Acute hypokinetic-rigid syndrome following SARS-CoV-2 infection.
  • Antonio Méndez-Guerrero
  • María Isabel Laespada-García
  • Adolfo Gómez-Grande
  • Mariano Ruiz-Ortiz
  • Víctor Antonio Blanco-Palmero
  • Francisco Javier Azcarate-Diaz
  • Pablo Rábano-Suárez
  • Eva Álvarez-Torres
  • Carlos Pablo de Fuenmayor-Fernández de la Hoz
  • Diana Vega Pérez
  • Raquel Rodríguez-Montalbán
  • Alfredo Pérez-Rivilla
  • Javier Sayas Catalán
  • Ana Ramos- González
  • Jesús González de la Aleja
  • Neurology.2020 Jul;10.1212/WNL.0000000000010282. doi: 10.1212/WNL.0000000000010282.Epub 2020-07-08.

Baicalinは、RhoA-ROCK経路を介してTh1およびTh17応答を抑制し、Treg応答を促進することで、敗血症に伴う膵臓損傷を改善することが示唆された

Baicalin suppresses Th1 and Th17 responses and promotes Treg response to ameliorate sepsis-associated pancreatic injury via the RhoA-ROCK pathway.
  • Pingping Liu
  • Zhenghui Xiao
  • Haipeng Yan
  • Xiulan Lu
  • Xinping Zhang
  • Lan Luo
  • Caixia Long
  • Yimin Zhu
  • Int. Immunopharmacol..2020 Jun;86:106685. S1567-5769(20)30273-3. doi: 10.1016/j.intimp.2020.106685.Epub 2020-06-19.

単細胞トランスクリプトミクスは、上咽頭癌の予後に関連する免疫細胞の多様性と免疫サブタイプの根底にある制御因子を明らかにした

Single-cell transcriptomics reveals regulators underlying immune cell diversity and immune subtypes associated with prognosis in nasopharyngeal carcinoma.
  • Yu-Pei Chen
  • Jian-Hua Yin
  • Wen-Fei Li
  • Han-Jie Li
  • Dong-Ping Chen
  • Cui-Juan Zhang
  • Jia-Wei Lv
  • Ya-Qin Wang
  • Xiao-Min Li
  • Jun-Yan Li
  • Pan-Pan Zhang
  • Ying-Qin Li
  • Qing-Mei He
  • Xiao-Jing Yang
  • Yuan Lei
  • Ling-Long Tang
  • Guan-Qun Zhou
  • Yan-Ping Mao
  • Chen Wei
  • Ke-Xu Xiong
  • Hong-Bo Zhang
  • Shi-Da Zhu
  • Yong Hou
  • Ying Sun
  • Michael Dean
  • Ido Amit
  • Kui Wu
  • Dong-Ming Kuang
  • Gui-Bo Li
  • Na Liu
  • Jun Ma
  • Cell Res..2020 Jul;10.1038/s41422-020-0374-x. doi: 10.1038/s41422-020-0374-x.Epub 2020-07-20.

妊娠糖尿病の予測因子としての皮下脂肪および内臓脂肪の超音波評価:システマティックレビュー

Ultrasound evaluation of subcutaneous and visceral abdominal fat as a predictor of gestational diabetes mellitus: a systematic review.
  • Fernanda Teixeira Benevides
  • Edward Araujo Júnior
  • Carla Soraya Costa Maia
  • Renan Magalhães Montenegro Junior
  • Francisco Herlânio Costa Carvalho
  • J. Matern. Fetal. Neonatal. Med..2020 Jun;:1-11. doi: 10.1080/14767058.2020.1781808.Epub 2020-06-21.

Joubert Syndromeにおける網膜電図検査。将来の標的治療の有効性を評価するための提案された客観的方法

Electroretinographic Assessment in Joubert Syndrome: A Suggested Objective Method to Evaluate the Effectiveness of Future Targeted Treatment.
  • Giulio Ruberto
  • Vincenzo Parisi
  • Chiara Bertone
  • Sabrina Signorini
  • Mauro Antonini
  • Enza Maria Valente
  • Federica Manzoni
  • Valentina Serpieri
  • Riccardo Fausto
  • Luciano Quaranta
  • Adv Ther.2020 Jul;10.1007/s12325-020-01432-9. doi: 10.1007/s12325-020-01432-9.Epub 2020-07-15.

ウイルスモニタリングのための磁性誘導性微小電極の設計:B型肝炎ウイルスのためのモデル化と実現可能性

Designing a magnetic inductive micro-electrode for virus monitoring: modelling and feasibility for hepatitis B virus.
  • Elias Alipour
  • Seyed Peyman Shariatpanahi
  • Hedayatollah Ghourchian
  • Benoit Piro
  • Morteza Fathipour
  • Seyed Mehdi Boutorabi
  • Sergey L Znoyko
  • Petr I Nikitin
  • Mikrochim Acta.2020 Jul;187(8):463. 10.1007/s00604-020-04429-x. doi: 10.1007/s00604-020-04429-x.Epub 2020-07-20.

アリニティーm HCVアッセイの性能の多施設臨床評価

Multicenter clinical evaluation of alinity m HCV assay performance.
  • Stéphane Chevaliez
  • Francesco Onelia
  • Monia Pacenti
  • Emily Goldstein
  • Juan-Carlos Galán
  • Laura Martínez-García
  • Alba Vilas
  • Allison Glass
  • Leana Maree
  • Maria Krügel
  • Robert Ehret
  • Heribert Knechten
  • Patrick Braun
  • Gudrun Naeth
  • Sara Bonanzinga
  • Kathy Jackson
  • Klara Abravaya
  • Jens Dhein
  • Shihai Huang
  • Ajith M Joseph
  • Danijela Lucic
  • Natalia Marlowe
  • Michael J Palm
  • Karin Pfeifer
  • Dan Toolsie
  • Birgit Reinhardt
  • Martin Obermeier
  • Rory Gunson
  • J. Clin. Virol..2020 Jul;129:104531. S1386-6532(20)30273-0. doi: 10.1016/j.jcv.2020.104531.Epub 2020-07-03.

MRI陰性の巣状皮質異形成IIB型患者における高度動的統計パラメトリックマッピングと脳磁図法を用いたてんかん原性焦点の検出

Detection of epileptogenic focus using advanced dynamic statistical parametric mapping with magnetoencephalography in a patient with MRI-negative focal cortical dysplasia type IIB.
  • Won Seok Chang
  • Midori Nakajima
  • Ayako Ochi
  • Elysa Widjaja
  • James T Rutka
  • Ivanna Yau
  • Shiro Baba
  • Hiroshi Otsubo
  • J Neurosurg Pediatr.2019 Oct;:1-5. 2019.7.PEDS1948. doi: 10.3171/2019.7.PEDS1948.Epub 2019-10-11.

N-パルミトイル-O-ホスホコリン-セリンとスフィンゴシルホスホリルコリンの同時液体クロマトグラフィー/タンデム質量分析に基づくニーマンピック病の診断スクリーニング法の開発

Development of a diagnostic screening strategy for Niemann-Pick diseases based on simultaneous liquid chromatography/tandem mass spectrometry analyses of N-palmitoyl-O-phosphocholine-serine and sphingosylphosphorylcholine.
  • Anna Iwahori
  • Masamitsu Maekawa
  • Aya Narita
  • Akie Kato
  • Toshihiro Sato
  • Jiro Ogura
  • Yu Sato
  • Masafumi Kikuchi
  • Atsuko Noguchi
  • Katsumi Higaki
  • Torayuki Okuyama
  • Tsutomu Takahashi
  • Yoshikatsu Eto
  • Nariyasu Mano
  • Biol. Pharm. Bull..2020 Jun;doi: 10.1248/bpb.b20-00400.Epub 2020-06-25.

小児、青年、若年成人における薬剤耐性てんかん治療におけるペランパネルの有効性と血清中濃度:12歳未満と12歳以上の患者の比較

Efficacy and serum concentrations of perampanel for treatment of drug-resistant epilepsy in children, adolescents, and young adults: comparison of patients younger and older than 12 years.
  • Satoru Ikemoto
  • Shin-Ichiro Hamano
  • Yuko Hirata
  • Ryuki Matsuura
  • Reiko Koichihara
  • Seizure.2019 Dec;73:75-78. S1059-1311(19)30136-0. doi: 10.1016/j.seizure.2019.10.023.Epub 2019-11-05.

冠動脈疾患治療のための5-リポキシゲナーゼ活性化蛋白質阻害剤の新規化学シリーズの開発

Novel Chemical Series of 5-Lipoxygenase-Activating Protein Inhibitors for Treatment of Coronary Artery Disease.
  • Malin Lemurell
  • Johan Ulander
  • Hans Emtenäs
  • Susanne Winiwarter
  • Johan Broddefalk
  • Marianne Swanson
  • Martin A Hayes
  • Luna Prieto Garcia
  • Annika Westin Eriksson
  • Johan Meuller
  • Johan Cassel
  • Gabrielle Saarinen
  • Zhong-Qing Yuan
  • Christian Löfberg
  • Staffan Karlsson
  • Monica Sundqvist
  • Carl Whatling
  • J. Med. Chem..2019 05;62(9):4325-4349. doi: 10.1021/acs.jmedchem.8b02012.Epub 2019-04-15.

前立腺閉塞症良性疾患に対するUNBLOCSランダム化比較試験における前立腺の経尿道的切除術対チュリウムレーザー経尿道的気化切除術のCost-Effectiveness

The Cost-Effectiveness of Transurethral resection of the prostate versus Thulium laser transurethral vaporesection of the prostate in the UNBLOCS randomised controlled trial for benign prostatic obstruction.
  • S M Noble
  • A M Ahern
  • J Worthington
  • H Hashim
  • H Taylor
  • G J Young
  • S Brookes
  • P Abrams
  • L Johnson
  • R Khan
  • T Page
  • S Swami
  • J A Lane
  • BJU Int..2020 Jun;doi: 10.1111/bju.15138.Epub 2020-06-17.

HIV感染者におけるcART開始後の治療変更:ドイツClinSurv HIVコホート2005-2017のレトロスペクティブ分析

Treatment modification after starting cART in people living with HIV: retrospective analysis of the German ClinSurv HIV Cohort 2005-2017.
  • Melanie Stecher
  • Philipp Schommers
  • Christian Kollan
  • Matthias Stoll
  • Frieder Kuhlendahl
  • Hans-Jürgen Stellbrink
  • Jan-Christian Wasmuth
  • Christoph Stephan
  • Laura Hamacher
  • Clara Lehmann
  • Christoph Boesecke
  • Johannes Bogner
  • Stefan Esser
  • Carlos Fritzsche
  • Annette Haberl
  • Christian Hoffmann
  • Björn Jensen
  • Carolynne Schwarze-Zander
  • Martin Platten
  • Gerd Fätkenheuer
  • Daniel Schmidt
  • Barbara Gunsenheimer-Bartmeyer
  • Jörg Janne Vehreschild
  • Infection.2020 Jul;10.1007/s15010-020-01469-6. doi: 10.1007/s15010-020-01469-6.Epub 2020-07-01.

Toll-like Receptor 4 (TLR4)の遮断は、高グルコースに曝露されたライディッヒ細胞において酸化ストレスを軽減し、phospho-ERK1/2レベルを回復させます

Blockade of Toll-like receptor 4 (TLR4) reduces oxidative stress and restores phospho-ERK1/2 levels in Leydig cells exposed to high glucose.
  • Tatiana Karpova
  • Amanda Almeida de Oliveira
  • Huda Naas
  • Fernanda Priviero
  • Kenia Pedrosa Nunes
  • Life Sci..2020 Mar;245:117365. S0024-3205(20)30112-0. doi: 10.1016/j.lfs.2020.117365.Epub 2020-01-27.

フェニル-2,4,6-トリメチルベンゾイルホスフィン酸リチウムで光重合したゼラチンメタクリロイル系ハイドロゲルのヒト初代腎近位尿細管上皮細胞における毒性と光増感性の評価

Toxicity and photosensitizing assessment of gelatin methacryloyl-based hydrogels photoinitiated with lithium phenyl-2,4,6-trimethylbenzoylphosphinate in human primary renal proximal tubule epithelial cells.
  • Alexander K Nguyen
  • Peter L Goering
  • Vytas Reipa
  • Roger J Narayan
  • Biointerphases.2019 05;14(2):021007. doi: 10.1116/1.5095886.Epub 2019-05-03.