あなたは歯科・医療関係者ですか?

WHITE CROSSは、歯科・医療現場で働く方を対象に、良質な歯科医療情報の提供を目的とした会員制サイトです。

日本語AIでPubMedを検索

日本語AIでPubMedを検索

PubMedの提供する医学論文データベースを日本語で検索できます。AI(Deep Learning)を活用した機械翻訳エンジンにより、精度高く日本語へ翻訳された論文をご参照いただけます。

みんなが読んでいる論文

化学療法中の顆粒球-コロニー刺激因子の使用とCA27.29と循環腫瘍細胞との関連性-SUCCESS A試験の結果

Use of Granulocyte-colony Stimulating Factor During Chemotherapy and Its Association With CA27.29 and Circulating Tumor Cells-Results From the SUCCESS A Trial.
  • Philip Hepp
  • Peter A Fasching
  • Matthias W Beckmann
  • Tanja Fehm
  • Jessica Salmen
  • Carsten Hagenbeck
  • Bernadette Jäger
  • Peter Widschwendter
  • Nikolaus de Gregorio
  • Fabienne Schochter
  • Sven Mahner
  • Nadia Harbeck
  • Tobias Weissenbacher
  • Ayse-Gül Kurt
  • Thomas W P Friedl
  • Wolfgang Janni
  • Brigitte Rack
  • Clin. Breast Cancer.2018 10;18(5):e1103-e1110. S1526-8209(17)30674-2. doi: 10.1016/j.clbc.2018.06.006.Epub 2018-06-18.

工学的に設計されたヒトカテリシジン抗菌ペプチドはエボラウイルス感染を抑制する

Engineered Human Cathelicidin Antimicrobial Peptides Inhibit Ebola Virus Infection.
  • Yangsheng Yu
  • Christopher L Cooper
  • Guangshun Wang
  • M Jane Morwitzer
  • Krishna Kota
  • Julie P Tran
  • Steven B Bradfute
  • Yan Liu
  • Jiayu Shao
  • Amanda K Zhang
  • Lindsey G Luo
  • St Patrick Reid
  • Steven H Hinrichs
  • Kaihong Su
  • iScience.2020 Mar;23(4):100999. S2589-0042(20)30183-8. doi: 10.1016/j.isci.2020.100999.Epub 2020-03-22.

ボロン酸で機能化した親水性表面を持つメソポーラス磁性粒子を用いて、糖プロテオミクスのための糖ペプチドのマルチモーダル濃縮を目指します

Boronic acid-functionalized mesoporous magnetic particles with a hydrophilic surface for the multimodal enrichment of glycopeptides for glycoproteomics.
  • Lujie Yang
  • Quanqing Zhang
  • Yuanyu Huang
  • Ling Lin
  • Hartmut Schlüter
  • Ke Wang
  • Cuiping Zhang
  • Pengyuan Yang
  • Hongxiu Yu
  • Analyst.2020 Jul;doi: 10.1039/d0an00648c.Epub 2020-07-03.

ナノ構造カーボンベース電気化学(バイオ)センサーの水域および水生生物中の新たな医薬品汚染物質のスクリーニングへの応用.A Review

Application of Nanostructured Carbon-Based Electrochemical (Bio)Sensors for Screening of Emerging Pharmaceutical Pollutants in Waters and Aquatic Species: A Review.
  • Álvaro Torrinha
  • Thiago M B F Oliveira
  • Francisco W P Ribeiro
  • Adriana N Correia
  • Pedro Lima-Neto
  • Simone Morais
  • Nanomaterials (Basel).2020 Jun;10(7). E1268. doi: 10.3390/nano10071268.Epub 2020-06-29.

ドイツにおける片頭痛患者の行政的有病率と罹患率,特徴,処方パターン:レトロスペクティブなクレームデータ分析

Administrative prevalence and incidence, characteristics and prescription patterns of patients with migraine in Germany: a retrospective claims data analysis.
  • Tatjana Roessler
  • Juergen Zschocke
  • Anne Roehrig
  • Michael Friedrichs
  • Heiko Friedel
  • Zaza Katsarava
  • J Headache Pain.2020 Jul;21(1):85. 10.1186/s10194-020-01154-x. doi: 10.1186/s10194-020-01154-x.Epub 2020-07-06.

血管内皮受容体チロシンホスファターゼ:EPHB4およびTIE2との接合体および三元複合体に関連する新規基質の同定

Vascular Endothelial Receptor Tyrosine Phosphatase: Identification of Novel Substrates Related to Junctions and a Ternary Complex with EPHB4 and TIE2.
  • Hannes C A Drexler
  • Matthias Vockel
  • Christian Polaschegg
  • Maike Frye
  • Kevin Peters
  • Dietmar Vestweber
  • Mol. Cell Proteomics.2019 10;18(10):2058-2077. RA119.001716. doi: 10.1074/mcp.RA119.001716.Epub 2019-08-19.

Lactobacillus rhamnosus 2016SWU.05.0601は、免疫関連転写因子および腸内細菌叢の発現を調節することにより、オーバルブミンに感作されたマウスにおける免疫バランスを調節する

Lactobacillus rhamnosus 2016SWU.05.0601 regulates immune balance in ovalbumin-sensitized mice by modulating expression of the immune-related transcription factors and gut microbiota.
  • Jiajia Song
  • Yang Li
  • Jian Li
  • Hongwei Wang
  • Yu Zhang
  • Huayi Suo
  • J. Sci. Food Agric..2020 Jun;doi: 10.1002/jsfa.10554.Epub 2020-06-01.

歯科医師が口腔癌や口腔内潜在的悪性病変の早期発見に用いる手がかり:全国歯科診療連携研究ネットワークからの知見

Cues used by dentists in the early detection of oral cancer and oral potentially malignant lesions: findings from the National Dental Practice-Based Research Network.
  • Alexander Ross Kerr
  • Michael E Robinson
  • Cyril Meyerowitz
  • Douglas E Morse
  • Maria L Aguilar
  • Scott L Tomar
  • Lisa Guerrero
  • Dianne Caprio
  • Linda M Kaste
  • Sonia K Makhija
  • Rahma Mungia
  • Linda Rasubala
  • Walter J Psoter
  • Oral Surg Oral Med Oral Pathol Oral Radiol.2020 May;S2212-4403(20)31011-7. doi: 10.1016/j.oooo.2020.05.007.Epub 2020-05-23.

ソヤサポニンIIは、マウスのYB-1リン酸化とNlrp3-inflammasomeプライミングを減少させることにより、急性肝不全を予防します

Soyasaponin II protects against acute liver failure through diminishing YB-1 phosphorylation and Nlrp3-inflammasome priming in mice.
  • Fangzhao Wang
  • Shenhai Gong
  • Teng Wang
  • Lei Li
  • Haihua Luo
  • Junhao Wang
  • Chenyang Huang
  • Hongwei Zhou
  • Guiming Chen
  • Zhanguo Liu
  • Qifan Zhang
  • Yong Jiang
  • Peng Chen
  • Theranostics.2020;10(6):2714-2726. thnov10p2714. doi: 10.7150/thno.40128.Epub 2020-02-03.

Chemotherapy and Venetoclax in Elderly Acute Myeloid Leukemia Trial(CAVEAT)。修正集中化学療法とベネトグラックス併用の第Ib相用量漸増試験

Chemotherapy and Venetoclax in Elderly Acute Myeloid Leukemia Trial (CAVEAT): A Phase Ib Dose-Escalation Study of Venetoclax Combined With Modified Intensive Chemotherapy.
  • Chong Chyn Chua
  • Andrew W Roberts
  • John Reynolds
  • Chun Yew Fong
  • Stephen B Ting
  • Jessica M Salmon
  • Sarah MacRaild
  • Adam Ivey
  • Ing Soo Tiong
  • Shaun Fleming
  • Fiona C Brown
  • Sun Loo
  • Ian J Majewski
  • Stefan K Bohlander
  • Andrew H Wei
  • J. Clin. Oncol..2020 Jul;:JCO2000572. doi: 10.1200/JCO.20.00572.Epub 2020-07-20.

YBX1ホモログYPSは、5-メチルシトシンRNAを優先的に認識することで卵巣生殖細胞幹細胞の発生を促進する

YBX1 homolog YPS promotes ovarian germ line stem cell development by preferentially recognizing 5-methylcytosine RNAs.
  • Fan Zou
  • Renjun Tu
  • Bo Duan
  • Zhenlin Yang
  • Zhaohua Ping
  • Xiaoqing Song
  • Shiyuan Chen
  • Andrew Price
  • Hua Li
  • Allison Scott
  • Anoja Perera
  • Sisi Li
  • Ting Xie
  • Proc. Natl. Acad. Sci. U.S.A..2020 02;117(7):3603-3609. 1910862117. doi: 10.1073/pnas.1910862117.Epub 2020-02-03.

ヒト免疫不全ウイルスおよびC型肝炎ウイルスに感染した患者における動脈硬化性心血管系イベント

Atherosclerotic Cardiovascular Events in Patients Infected With Human Immunodeficiency Virus and Hepatitis C Virus.
  • Boun Kim Tan
  • Mathieu Chalouni
  • Dominique Salmon Ceron
  • Alexandre Cinaud
  • Laure Esterle
  • Marc Arthur Loko
  • Christine Katlama
  • Isabelle Poizot-Martin
  • Didier Neau
  • Julie Chas
  • Philippe Morlat
  • Eric Rosenthal
  • Karine Lacombe
  • Alissa Naqvi
  • Karl Barange
  • Olivier Bouchaud
  • Anne Gervais
  • Caroline Lascoux-Combe
  • Daniel Garipuy
  • Laurent Alric
  • Cécile Goujard
  • Patrick Miailhes
  • Hugues Aumaitre
  • Claudine Duvivier
  • Anne Simon
  • Jose-Luis Lopez-Zaragoza
  • David Zucman
  • François Raffi
  • Estibaliz Lazaro
  • David Rey
  • Lionel Piroth
  • François Boué
  • Camille Gilbert
  • Firouzé Bani-Sadr
  • François Dabis
  • Philippe Sogni
  • Linda Wittkop
  • Franck Boccara
  • Clin. Infect. Dis..2020 Jul;ciaa1014. doi: 10.1093/cid/ciaa1014.Epub 2020-07-20.

アペリンは、アペリン受容体、プロテインキナーゼA、細胞外シグナル制御キナーゼ1/2活性化を介して、ヒトトロフォブラストBeWo細胞による胎盤ホルモン分泌を減少させた

Apelin decreased placental hormoine secretion by human trophoblast BeWo cells via apelin receptor, protein kinase A and extracellular signal-regulated kinases 1/2 activation.
  • M Dawid
  • E Mlyczynska
  • P Kurowska
  • M Sierpowski
  • A Rak
  • J. Physiol. Pharmacol..2019 Dec;70(6). doi: 10.26402/jpp.2019.6.08.Epub 2020-02-19.

P21の組換え型は宿主の免疫応答を調節することで感染を制御している

The Recombinant Form of P21 Controls Infection by Modulating Host Immune Response.
  • Flávia Alves Martins
  • Marlus Alves Dos Santos
  • Júlia de Gouveia Santos
  • Aline Alves da Silva
  • Bruna Cristina Borges
  • Mylla Spirandelli da Costa
  • Paula Cristina Brígido Tavares
  • Samuel Cota Teixeira
  • Rebecca Tavares E Silva Brígido
  • Thaise Lara Teixeira
  • Cassiano Costa Rodrigues
  • Nadjania Saraiva de Lira Silva
  • Rayane Cristina de Oliveira
  • Laura Caroline de Faria
  • Marcela Rezende Lemes
  • Renata Graciele Zanon
  • Tatiana Carla Tomiosso
  • Juliana Reis Machado
  • Marcos Vinicius da Silva
  • Carlo José Freire Oliveira
  • Claudio Vieira da Silva
  • Front Immunol.2020;11:1010. doi: 10.3389/fimmu.2020.01010.Epub 2020-06-05.

イリ科植物のファイトケミカル組成とインビトロ生物学的活性.口腔内細菌バイオフィルムの抑制のための新たな生理活性成分の供給源

Phytochemical Composition and In Vitro Biological Activity of spp. (Iridaceae): A New Source of Bioactive Constituents for the Inhibition of Oral Bacterial Biofilms.
  • Lan Hoang
  • František Beneš
  • Marie Fenclová
  • Olga Kronusová
  • Viviana Švarcová
  • Kateřina Řehořová
  • Eva Baldassarre Švecová
  • Miroslav Vosátka
  • Jana Hajšlová
  • Petr Kaštánek
  • Jitka Viktorová
  • Tomáš Ruml
  • Antibiotics (Basel).2020 Jul;9(7). E403. doi: 10.3390/antibiotics9070403.Epub 2020-07-11.

2つの木材腐朽菌Ganoderma applanatumとLaetiporus sulphureusによるNSAIDsの新規コビマス分解。リグニン分解酵素の誘導、等温および速度論的研究

Novel cobiomass degradation of NSAIDs by two wood rot fungi, Ganoderma applanatum and Laetiporus sulphureus: Ligninolytic enzymes induction, isotherm and kinetic studies.
  • Paul Olusegun Bankole
  • Adedotun Adeyinka Adekunle
  • Byong-Hun Jeon
  • Sanjay Prabhu Govindwar
  • Ecotoxicol. Environ. Saf..2020 Jul;203:110997. S0147-6513(20)30836-8. doi: 10.1016/j.ecoenv.2020.110997.Epub 2020-07-16.

Alinity m HIV-1アッセイの性能の多施設臨床比較評価

Multicenter clinical comparative evaluation of Alinity m HIV-1 assay performance.
  • Patrick Braun
  • Allison Glass
  • Leana Maree
  • Maria Krügel
  • Monia Pacenti
  • Francesco Onelia
  • Rory Gunson
  • Emily Goldstein
  • Laura Martínez-García
  • Juan-Carlos Galán
  • Alba Vilas
  • Jodie D'costa
  • Rizmina Sameer
  • Robert Ehret
  • Heribert Knechten
  • Gudrun Naeth
  • Magali Bouvier-Alias
  • Natalia Marlowe
  • Michael J Palm
  • Ajith M Joseph
  • Jens Dhein
  • Birgit Reinhardt
  • Karin Pfeifer
  • Danijela Lucic
  • Martin Obermeier
  • J. Clin. Virol..2020 Jul;129:104530. S1386-6532(20)30272-9. doi: 10.1016/j.jcv.2020.104530.Epub 2020-07-03.

CTGリピート選択的化学スクリーニングにより、微小管阻害剤が有毒CUG RNAレベルの選択的調節因子として同定された

A CTG repeat-selective chemical screen identifies microtubule inhibitors as selective modulators of toxic CUG RNA levels.
  • Kaalak Reddy
  • Jana R Jenquin
  • Ona L McConnell
  • John D Cleary
  • Jared I Richardson
  • Belinda S Pinto
  • Maja C Haerle
  • Elizabeth Delgado
  • Lori Planco
  • Masayuki Nakamori
  • Eric T Wang
  • J Andrew Berglund
  • Proc. Natl. Acad. Sci. U.S.A..2019 10;116(42):20991-21000. 1901893116. doi: 10.1073/pnas.1901893116.Epub 2019-09-30.

SARS-CoV-2感染後の急性低運動性硬直症候群

Acute hypokinetic-rigid syndrome following SARS-CoV-2 infection.
  • Antonio Méndez-Guerrero
  • María Isabel Laespada-García
  • Adolfo Gómez-Grande
  • Mariano Ruiz-Ortiz
  • Víctor Antonio Blanco-Palmero
  • Francisco Javier Azcarate-Diaz
  • Pablo Rábano-Suárez
  • Eva Álvarez-Torres
  • Carlos Pablo de Fuenmayor-Fernández de la Hoz
  • Diana Vega Pérez
  • Raquel Rodríguez-Montalbán
  • Alfredo Pérez-Rivilla
  • Javier Sayas Catalán
  • Ana Ramos- González
  • Jesús González de la Aleja
  • Neurology.2020 Jul;10.1212/WNL.0000000000010282. doi: 10.1212/WNL.0000000000010282.Epub 2020-07-08.

Baicalinは、RhoA-ROCK経路を介してTh1およびTh17応答を抑制し、Treg応答を促進することで、敗血症に伴う膵臓損傷を改善することが示唆された

Baicalin suppresses Th1 and Th17 responses and promotes Treg response to ameliorate sepsis-associated pancreatic injury via the RhoA-ROCK pathway.
  • Pingping Liu
  • Zhenghui Xiao
  • Haipeng Yan
  • Xiulan Lu
  • Xinping Zhang
  • Lan Luo
  • Caixia Long
  • Yimin Zhu
  • Int. Immunopharmacol..2020 Jun;86:106685. S1567-5769(20)30273-3. doi: 10.1016/j.intimp.2020.106685.Epub 2020-06-19.

単細胞トランスクリプトミクスは、上咽頭癌の予後に関連する免疫細胞の多様性と免疫サブタイプの根底にある制御因子を明らかにした

Single-cell transcriptomics reveals regulators underlying immune cell diversity and immune subtypes associated with prognosis in nasopharyngeal carcinoma.
  • Yu-Pei Chen
  • Jian-Hua Yin
  • Wen-Fei Li
  • Han-Jie Li
  • Dong-Ping Chen
  • Cui-Juan Zhang
  • Jia-Wei Lv
  • Ya-Qin Wang
  • Xiao-Min Li
  • Jun-Yan Li
  • Pan-Pan Zhang
  • Ying-Qin Li
  • Qing-Mei He
  • Xiao-Jing Yang
  • Yuan Lei
  • Ling-Long Tang
  • Guan-Qun Zhou
  • Yan-Ping Mao
  • Chen Wei
  • Ke-Xu Xiong
  • Hong-Bo Zhang
  • Shi-Da Zhu
  • Yong Hou
  • Ying Sun
  • Michael Dean
  • Ido Amit
  • Kui Wu
  • Dong-Ming Kuang
  • Gui-Bo Li
  • Na Liu
  • Jun Ma
  • Cell Res..2020 Jul;10.1038/s41422-020-0374-x. doi: 10.1038/s41422-020-0374-x.Epub 2020-07-20.

妊娠糖尿病の予測因子としての皮下脂肪および内臓脂肪の超音波評価:システマティックレビュー

Ultrasound evaluation of subcutaneous and visceral abdominal fat as a predictor of gestational diabetes mellitus: a systematic review.
  • Fernanda Teixeira Benevides
  • Edward Araujo Júnior
  • Carla Soraya Costa Maia
  • Renan Magalhães Montenegro Junior
  • Francisco Herlânio Costa Carvalho
  • J. Matern. Fetal. Neonatal. Med..2020 Jun;:1-11. doi: 10.1080/14767058.2020.1781808.Epub 2020-06-21.

Joubert Syndromeにおける網膜電図検査。将来の標的治療の有効性を評価するための提案された客観的方法

Electroretinographic Assessment in Joubert Syndrome: A Suggested Objective Method to Evaluate the Effectiveness of Future Targeted Treatment.
  • Giulio Ruberto
  • Vincenzo Parisi
  • Chiara Bertone
  • Sabrina Signorini
  • Mauro Antonini
  • Enza Maria Valente
  • Federica Manzoni
  • Valentina Serpieri
  • Riccardo Fausto
  • Luciano Quaranta
  • Adv Ther.2020 Jul;10.1007/s12325-020-01432-9. doi: 10.1007/s12325-020-01432-9.Epub 2020-07-15.

ウイルスモニタリングのための磁性誘導性微小電極の設計:B型肝炎ウイルスのためのモデル化と実現可能性

Designing a magnetic inductive micro-electrode for virus monitoring: modelling and feasibility for hepatitis B virus.
  • Elias Alipour
  • Seyed Peyman Shariatpanahi
  • Hedayatollah Ghourchian
  • Benoit Piro
  • Morteza Fathipour
  • Seyed Mehdi Boutorabi
  • Sergey L Znoyko
  • Petr I Nikitin
  • Mikrochim Acta.2020 Jul;187(8):463. 10.1007/s00604-020-04429-x. doi: 10.1007/s00604-020-04429-x.Epub 2020-07-20.

アリニティーm HCVアッセイの性能の多施設臨床評価

Multicenter clinical evaluation of alinity m HCV assay performance.
  • Stéphane Chevaliez
  • Francesco Onelia
  • Monia Pacenti
  • Emily Goldstein
  • Juan-Carlos Galán
  • Laura Martínez-García
  • Alba Vilas
  • Allison Glass
  • Leana Maree
  • Maria Krügel
  • Robert Ehret
  • Heribert Knechten
  • Patrick Braun
  • Gudrun Naeth
  • Sara Bonanzinga
  • Kathy Jackson
  • Klara Abravaya
  • Jens Dhein
  • Shihai Huang
  • Ajith M Joseph
  • Danijela Lucic
  • Natalia Marlowe
  • Michael J Palm
  • Karin Pfeifer
  • Dan Toolsie
  • Birgit Reinhardt
  • Martin Obermeier
  • Rory Gunson
  • J. Clin. Virol..2020 Jul;129:104531. S1386-6532(20)30273-0. doi: 10.1016/j.jcv.2020.104531.Epub 2020-07-03.