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日本語AIでPubMedを検索

日本語AIでPubMedを検索

PubMedの提供する医学論文データベースを日本語で検索できます。AI(Deep Learning)を活用した機械翻訳エンジンにより、精度高く日本語へ翻訳された論文をご参照いただけます。

みんなが読んでいる論文

大腸がん患者におけるイレオストミー閉鎖後の手術部位感染に対する陰圧創傷治療の評価:前向き多施設試験

Evaluation of negative-pressure wound therapy for surgical site infections after ileostomy closure in colorectal cancer patients: a prospective multicenter study.
  • Koichi Okuya
  • Ichiro Takemasa
  • Tetsuhiro Tsuruma
  • Ai Noda
  • Kenichi Sasaki
  • Tomomi Ueki
  • Mitsuhiro Mukaiya
  • Keita Saito
  • Kenji Okita
  • Toshihiko Nishidate
  • Emi Akizuki
  • Atsushi Hamabe
  • Masayuki Ishii
  • Surg. Today.2020 Jul;10.1007/s00595-020-02068-6. doi: 10.1007/s00595-020-02068-6.Epub 2020-07-07.

正方かごめ格子反強磁性体中のギャップレススピン液体

Gapless spin liquid in a square-kagome lattice antiferromagnet.
  • Masayoshi Fujihala
  • Katsuhiro Morita
  • Richard Mole
  • Setsuo Mitsuda
  • Takami Tohyama
  • Shin-Ichiro Yano
  • Dehong Yu
  • Shigetoshi Sota
  • Tomohiko Kuwai
  • Akihiro Koda
  • Hirotaka Okabe
  • Hua Lee
  • Shinichi Itoh
  • Takafumi Hawai
  • Takatsugu Masuda
  • Hajime Sagayama
  • Akira Matsuo
  • Koichi Kindo
  • Seiko Ohira-Kawamura
  • Kenji Nakajima
  • Nat Commun.2020 Jul;11(1):3429. 10.1038/s41467-020-17235-z. doi: 10.1038/s41467-020-17235-z.Epub 2020-07-09.

高齢者向けオンライン・ソーシャル・サポート・プラットフォーム設計のためのユーザー中心アプローチ:ユーザーのタイプと要件の特定

User-Centred Approach to Design an Online Social Support Platform for Seniors : Identification of Users' Types and Their Requirements.
  • Arnaud Ricci
  • Jessica Rochat
  • Henk Herman Nap
  • Lotte Cornelisse
  • Christian Lovis
  • Frédéric Ehrler
  • Stud Health Technol Inform.2020 Jun;270:1081-1085. SHTI200328. doi: 10.3233/SHTI200328.

HARS1の二項対立変異は、ヒスチジルtRNA合成酵素の発現と酵素活性を著しく低下させ、新規の多系統運動失調症候群を引き起こす

Bi-allelic mutations in HARS1 severely impair histidyl-tRNA synthetase expression and enzymatic activity causing a novel multisystem ataxic syndrome.
  • Daniele Galatolo
  • Molly E Kuo
  • Patrick Mullen
  • Rebecca Meyer-Schuman
  • Stefano Doccini
  • Roberta Battini
  • Maria Lieto
  • Alessandra Tessa
  • Alessandro Filla
  • Christopher Francklyn
  • Anthony Antonellis
  • Filippo M Santorelli
  • Hum. Mutat..2020 Jul;41(7):1232-1237. doi: 10.1002/humu.24024.Epub 2020-04-29.

組換えスパイク蛋白質のワクチン接種によるラマにおける中東呼吸器症候群コロナウイルス(MERS-CoV)の感染をブロックする

Blocking transmission of Middle East respiratory syndrome coronavirus (MERS-CoV) in llamas by vaccination with a recombinant spike protein.
  • Jordi Rodon
  • Nisreen M A Okba
  • Nigeer Te
  • Brenda van Dieren
  • Berend-Jan Bosch
  • Albert Bensaid
  • Joaquim Segalés
  • Bart L Haagmans
  • Júlia Vergara-Alert
  • Emerg Microbes Infect.2019;8(1):1593-1603. doi: 10.1080/22221751.2019.1685912.

ソフォスブビルは肝細胞におけるEGFR依存性経路を活性化し、肝関連の病理学的プロセスに影響を及ぼすことが示唆された

Sofosbuvir Activates EGFR-Dependent Pathways in Hepatoma Cells with Implications for Liver-Related Pathological Processes.
  • Denisa Bojkova
  • Sandra Westhaus
  • Rui Costa
  • Lejla Timmer
  • Nora Funkenberg
  • Marek Korencak
  • Hendrik Streeck
  • Florian Vondran
  • Ruth Broering
  • Stefan Heinrichs
  • Karl S Lang
  • Sandra Ciesek
  • Cells.2020 Apr;9(4). E1003. doi: 10.3390/cells9041003.Epub 2020-04-17.

南イタリアの非成人の認知健康。卓越した長寿の横断的、家庭ベースのパイロット研究(Cilento Initiative on Aging Outcomes or CIAO)からの記述的分析

Cognitive Health of Nonagenarians in Southern Italy: A Descriptive Analysis from a Cross-Sectional, Home-Based Pilot Study of Exceptional Longevity (Cilento Initiative on Aging Outcomes Or CIAO).
  • Vincenzo Pizza
  • Paola Antonini
  • Rosella Marino
  • Giovanni D'Arena
  • Serena Grazia Lucibello
  • Marianna Rizzo
  • David A Brenner
  • Dilip V Jeste
  • Salvatore Di Somma
  • Medicina (Kaunas).2020 May;56(5). E218. doi: 10.3390/medicina56050218.Epub 2020-05-05.

Achillea abrotanoides (Vis.) Vis.からの新しいロンギピナンケトン:精油の化学変換により、マイナーな成分の同定が可能になった

A new longipinane ketone from Achillea abrotanoides (Vis.) Vis.: chemical transformation of the essential oil enables the identification of a minor constituent.
  • Niko S Radulović
  • Marko Z Mladenović
  • Milenko N Ristić
  • Vidoslav S Dekić
  • Biljana R Dekić
  • Novica R Ristić
  • Phytochem Anal.2020 Jul;31(4):501-515. doi: 10.1002/pca.2913.Epub 2020-01-24.

HIV-1コントローラーにおけるCDKN1A/p21の発現増加は、ZC3H12A/MCPIP1の発現増加と相関していた

Increased expression of CDKN1A/p21 in HIV-1 controllers is correlated with upregulation of ZC3H12A/MCPIP1.
  • Suwellen S D de Azevedo
  • Marcelo Ribeiro-Alves
  • Fernanda H Côrtes
  • Edson Delatorre
  • Lucia Spangenberg
  • Hugo Naya
  • Leonardo N Seito
  • Brenda Hoagland
  • Beatriz Grinsztejn
  • Valdilea G Veloso
  • Mariza G Morgado
  • Thiago Moreno L Souza
  • Gonzalo Bello
  • Retrovirology.2020 Jul;17(1):18. 10.1186/s12977-020-00522-4. doi: 10.1186/s12977-020-00522-4.Epub 2020-07-02.

アキレアミレフォリウムヘキサン抽出物とその主な生理活性化合物のカルシウムチャネル遮断による気管緩和作用

Tracheal relaxation through calcium channel blockade of Achillea millefolium hexanic extract and its main bioactive compounds.
  • Luis Arias-Durán
  • Samuel Estrada-Soto
  • Monserrat Hernández-Morales
  • Fabiola Chávez-Silva
  • Gabriel Navarrete-Vázquez
  • Ismael León-Rivera
  • Irene Perea-Arango
  • Rafael Villalobos-Molina
  • Maximiliano Ibarra-Barajas
  • J Ethnopharmacol.2020 May;253:112643. S0378-8741(19)34431-9. doi: 10.1016/j.jep.2020.112643.Epub 2020-02-05.

生態系代謝は熱帯汽水湿地におけるアタイドシュリンプ(Neocaridina denticulata)における金属の季節的な生物蓄積を制御している

Ecosystem metabolism regulates seasonal bioaccumulation of metals in atyid shrimp (Neocaridina denticulata) in a tropical brackish wetland.
  • Cheng-Hao Tang
  • Wei-Yu Chen
  • Chin-Ching Wu
  • Ezekiel Lu
  • Wan-Yu Shih
  • Jein-Wen Chen
  • Jeng-Wei Tsai
  • Aquat. Toxicol..2020 Jun;225:105522. S0166-445X(20)30272-1. doi: 10.1016/j.aquatox.2020.105522.Epub 2020-06-04.

ヒト細胞におけるDNA損傷応答の遺伝地図

A Genetic Map of the Response to DNA Damage in Human Cells.
  • Michele Olivieri
  • Tiffany Cho
  • Alejandro Álvarez-Quilón
  • Kejiao Li
  • Matthew J Schellenberg
  • Michal Zimmermann
  • Nicole Hustedt
  • Silvia Emma Rossi
  • Salomé Adam
  • Henrique Melo
  • Anne Margriet Heijink
  • Guillermo Sastre-Moreno
  • Nathalie Moatti
  • Rachel K Szilard
  • Andrea McEwan
  • Alexanda K Ling
  • Almudena Serrano-Benitez
  • Tajinder Ubhi
  • Sumin Feng
  • Judy Pawling
  • Irene Delgado-Sainz
  • Michael W Ferguson
  • James W Dennis
  • Grant W Brown
  • Felipe Cortés-Ledesma
  • R Scott Williams
  • Alberto Martin
  • Dongyi Xu
  • Daniel Durocher
  • Cell.2020 Jul;S0092-8674(20)30673-5. doi: 10.1016/j.cell.2020.05.040.Epub 2020-07-09.

新規設計薬である1-(2,3-ジヒドロ-1H-インデン-5-イル)-2-(ピロリジン-1-イル)ブタン-1-オン(5-PPDI)のヒト尿中での第I相代謝物の研究

Studies on the phase I metabolites of the new designer drug 1-(2,3-dihydro-1H-inden-5-yl)-2-(pyrrolidine-1-yl)butan-1-one (5-PPDI) in human urine.
  • Ayumu Ishii
  • Kosuke Kusakabe
  • Noriyuki Kato
  • Shin-Ichi Sasaki
  • Kenji Tsujikawa
  • Takeshi Wada
  • Forensic Sci. Int..2020 May;310:110214. S0379-0738(20)30076-1. doi: 10.1016/j.forsciint.2020.110214.Epub 2020-02-29.

鉛に起因するマウス腎細胞におけるセレン含有タンパク質-グルタチオンペルオキシダーゼ3の不活性化に関するin vivoおよびin vitroでの研究

In vivo and in vitro studies on inactivation of selenium containing protein- glutathione peroxidase 3 in mice nephrocytes caused by lead.
  • Hao Zhang
  • Lingyu Luan
  • Mengjiao Bi
  • Lining Zhao
  • Lin Yuan
  • Jia Feng
  • Rutao Liu
  • Ecotoxicol. Environ. Saf..2020 Jul;203:111008. S0147-6513(20)30847-2. doi: 10.1016/j.ecoenv.2020.111008.Epub 2020-07-17.

急性冠症候群患者における大出血および心血管イベントに対するチカクレラー単剤療法とチカクレラーとアスピリンの併用療法の効果。TICO無作為化臨床試験

Effect of Ticagrelor Monotherapy vs Ticagrelor With Aspirin on Major Bleeding and Cardiovascular Events in Patients With Acute Coronary Syndrome: The TICO Randomized Clinical Trial.
  • Byeong-Keuk Kim
  • Sung-Jin Hong
  • Yun-Hyeong Cho
  • Kyeong Ho Yun
  • Yong Hoon Kim
  • Yongsung Suh
  • Jae Young Cho
  • Ae-Young Her
  • Sungsoo Cho
  • Dong Woon Jeon
  • Sang-Yong Yoo
  • Deok-Kyu Cho
  • Bum-Kee Hong
  • Hyuckmoon Kwon
  • Chul-Min Ahn
  • Dong-Ho Shin
  • Chung-Mo Nam
  • Jung-Sun Kim
  • Young-Guk Ko
  • Donghoon Choi
  • Myeong-Ki Hong
  • Yangsoo Jang
  • JAMA.2020 06;323(23):2407-2416. 2767161. doi: 10.1001/jama.2020.7580.

Geobacillus stearothermophilus由来L-アラビノースイソメラーゼの酸性条件下での活性向上のための発現と特性評価

Expression and characterization of L-arabinose isomerase from Geobacillus stearothermophilus for improved activity under acidic condition.
  • Fina Amreta Laksmi
  • Shigeki Arai
  • Tsutomu Arakawa
  • Hirohito Tsurumaru
  • Yoshitaka Nakamura
  • Budi Saksono
  • Masao Tokunaga
  • Matsujiro Ishibashi
  • Protein Expr. Purif..2020 Jul;:105692. S1046-5928(20)30283-7. doi: 10.1016/j.pep.2020.105692.Epub 2020-07-15.

駆出率が低下した心不全患者のプロファイルがガイドラインに沿った薬物療法のアドヒアランスに与える影響。VCOR-HF試験

Impact of Individual Patient Profiles on Adherence to Guideline Directed Medical Therapy in Heart Failure With Reduced Ejection Fraction: VCOR-HF Study.
  • Andrea Driscoll
  • Diem Dinh
  • James Wong
  • Ingrid Hopper
  • Justin Mariani
  • Hendrik Zimmet
  • Angela Brennan
  • Jeffery Lefkovits
  • Harriet Carruthers
  • Christopher M Reid
  • Heart Lung Circ.2020 Jun;S1443-9506(20)30238-9. doi: 10.1016/j.hlc.2020.04.012.Epub 2020-06-25.

分野横断的な健康政策とシステム研究の批判的現実主義的統合:特徴的な特徴の定義、評価フレームワークの開発、課題の特定

A critical realist synthesis of cross-disciplinary health policy and systems research: defining characteristic features, developing an evaluation framework and identifying challenges.
  • Gordon Dugle
  • Joseph Kwame Wulifan
  • John Paul Tanyeh
  • Wilm Quentin
  • Health Res Policy Syst.2020 Jul;18(1):79. 10.1186/s12961-020-00556-2. doi: 10.1186/s12961-020-00556-2.Epub 2020-07-14.

次世代シークエンシングによる突然変異陰性先天性好中球減少症の遺伝的バリアントのスクリーニング

Screening of genetic variants in mutation negative congenital neutropenia by next generation sequencing.
  • Arun Kumar Arunachalam
  • Hemamalini Suresh
  • Eunice Sindhuvi Edison
  • Anu Korula
  • Fouzia N Aboobacker
  • Biju George
  • Ramachandran V Shaji
  • Vikram Mathews
  • Poonkuzhali Balasubramanian
  • J. Clin. Pathol..2020 Jun;73(6):322-327. jclinpath-2019-206306. doi: 10.1136/jclinpath-2019-206306.Epub 2019-11-15.

腎細胞癌患者における繊毛新生と VDAC1-ΔC の非存在によって駆動される新たな攻撃性軸の同定

Identification of a new aggressive axis driven by ciliogenesis and absence of VDAC1-ΔC in clear cell Renal Cell Carcinoma patients.
  • Lucilla Fabbri
  • Maeva Dufies
  • Sandra Lacas-Gervais
  • Betty Gardie
  • Sophie Gad-Lapiteau
  • Julien Parola
  • Nicolas Nottet
  • Monique Meyenberg Cunha de Padua
  • Julie Contenti
  • Delphine Borchiellini
  • Jean-Marc Ferrero
  • Nathalie Rioux Leclercq
  • Damien Ambrosetti
  • Baharia Mograbi
  • Stéphane Richard
  • Julien Viotti
  • Emmanuel Chamorey
  • Nirvana Sadaghianloo
  • Matthieu Rouleau
  • William J Craigen
  • Bernard Mari
  • Stéphan Clavel
  • Gilles Pagès
  • Jacques Pouysségur
  • Frédéric Bost
  • Nathalie M Mazure
  • Theranostics.2020;10(6):2696-2713. thnov10p2696. doi: 10.7150/thno.41001.Epub 2020-02-03.

ギラン・バレ症候群と診断されたメキシコ人成人の電気生理学的サブタイプと関連する予後因子、単一施設での経験

Electrophysiological subtypes and associated prognosis factors of Mexican adults diagnosed with Guillain-Barré syndrome, a single center experience.
  • Juan Carlos López-Hernández
  • Luis Enrique Colunga-Lozano
  • Sofia Garcia-Trejo
  • Enrique Gomez-Figueroa
  • Guillermo Delgado-Garcia
  • Lisette Bazán-Rodríguez
  • Roberto Cervantes-Uribe
  • Jorge Burgos-Centeno
  • Francisca Fernandez-Valverde
  • Edwin Steven Vargas-Cañas
  • J Clin Neurosci.2020 Jul;S0967-5868(20)30394-5. doi: 10.1016/j.jocn.2020.04.059.Epub 2020-07-13.

ペパーミント(Mentha piperita)粉末の食餌摂取は、カスピ海ローチ(Rutilus caspicus)における成長能、血液学的指標、皮膚粘膜免疫パラメータ、成長およびストレス関連遺伝子の発現に影響を与えます

Dietary peppermint (Mentha piperita) powder affects growth performance, hematological indices, skin mucosal immune parameters, and expression of growth and stress-related genes in Caspian roach (Rutilus caspicus).
  • Hammed Paknejad
  • Seyed Pezhman Hosseini Shekarabi
  • Mehdi Shamsaie Mehrgan
  • Abdolmajid Hajimoradloo
  • Zohre Khorshidi
  • Soheila Rastegari
  • Fish Physiol. Biochem..2020 Jun;10.1007/s10695-020-00839-z. doi: 10.1007/s10695-020-00839-z.Epub 2020-06-26.

ボルテゾミブの神経毒性はカーフィルゾミブに比べてミトコンドリア損傷よりも高いプロテアソームストレスが関与している

Higher proteotoxic stress rather than mitochondrial damage is involved in higher neurotoxicity of bortezomib compared to carfilzomib.
  • Ayse Tarbin Jannuzzi
  • Sema Arslan
  • Ayse Mine Yilmaz
  • Gulce Sari
  • Hande Beklen
  • Lucía Méndez
  • Maria Fedorova
  • Kazim Yalcin Arga
  • Betul Karademir Yilmaz
  • Buket Alpertunga
  • Redox Biol.2020 05;32:101502. S2213-2317(19)31437-5. doi: 10.1016/j.redox.2020.101502.Epub 2020-03-21.

再発性多発性硬化症患者における腸管透過性の変化。パイロット研究

Altered intestinal permeability in patients with relapsing-remitting multiple sclerosis: A pilot study.
  • Maria Chiara Buscarinu
  • Benedetta Cerasoli
  • Viviana Annibali
  • Claudia Policano
  • Luana Lionetto
  • Matilde Capi
  • Rosella Mechelli
  • Silvia Romano
  • Arianna Fornasiero
  • Gianluca Mattei
  • Eleonora Piras
  • Daniela Francesca Angelini
  • Luca Battistini
  • Maurizio Simmaco
  • Renato Umeton
  • Marco Salvetti
  • Giovanni Ristori
  • Mult. Scler..2017 Mar;23(3):442-446. 1352458516652498. doi: 10.1177/1352458516652498.Epub 2016-07-11.