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日本語AIでPubMedを検索

日本語AIでPubMedを検索

PubMedの提供する医学論文データベースを日本語で検索できます。AI(Deep Learning)を活用した機械翻訳エンジンにより、精度高く日本語へ翻訳された論文をご参照いただけます。

みんなが読んでいる論文

MRI陰性の巣状皮質異形成IIB型患者における高度動的統計パラメトリックマッピングと脳磁図法を用いたてんかん原性焦点の検出

Detection of epileptogenic focus using advanced dynamic statistical parametric mapping with magnetoencephalography in a patient with MRI-negative focal cortical dysplasia type IIB.
  • Won Seok Chang
  • Midori Nakajima
  • Ayako Ochi
  • Elysa Widjaja
  • James T Rutka
  • Ivanna Yau
  • Shiro Baba
  • Hiroshi Otsubo
  • J Neurosurg Pediatr.2019 Oct;:1-5. 2019.7.PEDS1948. doi: 10.3171/2019.7.PEDS1948.Epub 2019-10-11.

N-パルミトイル-O-ホスホコリン-セリンとスフィンゴシルホスホリルコリンの同時液体クロマトグラフィー/タンデム質量分析に基づくニーマンピック病の診断スクリーニング法の開発

Development of a diagnostic screening strategy for Niemann-Pick diseases based on simultaneous liquid chromatography/tandem mass spectrometry analyses of N-palmitoyl-O-phosphocholine-serine and sphingosylphosphorylcholine.
  • Anna Iwahori
  • Masamitsu Maekawa
  • Aya Narita
  • Akie Kato
  • Toshihiro Sato
  • Jiro Ogura
  • Yu Sato
  • Masafumi Kikuchi
  • Atsuko Noguchi
  • Katsumi Higaki
  • Torayuki Okuyama
  • Tsutomu Takahashi
  • Yoshikatsu Eto
  • Nariyasu Mano
  • Biol. Pharm. Bull..2020 Jun;doi: 10.1248/bpb.b20-00400.Epub 2020-06-25.

小児、青年、若年成人における薬剤耐性てんかん治療におけるペランパネルの有効性と血清中濃度:12歳未満と12歳以上の患者の比較

Efficacy and serum concentrations of perampanel for treatment of drug-resistant epilepsy in children, adolescents, and young adults: comparison of patients younger and older than 12 years.
  • Satoru Ikemoto
  • Shin-Ichiro Hamano
  • Yuko Hirata
  • Ryuki Matsuura
  • Reiko Koichihara
  • Seizure.2019 Dec;73:75-78. S1059-1311(19)30136-0. doi: 10.1016/j.seizure.2019.10.023.Epub 2019-11-05.

冠動脈疾患治療のための5-リポキシゲナーゼ活性化蛋白質阻害剤の新規化学シリーズの開発

Novel Chemical Series of 5-Lipoxygenase-Activating Protein Inhibitors for Treatment of Coronary Artery Disease.
  • Malin Lemurell
  • Johan Ulander
  • Hans Emtenäs
  • Susanne Winiwarter
  • Johan Broddefalk
  • Marianne Swanson
  • Martin A Hayes
  • Luna Prieto Garcia
  • Annika Westin Eriksson
  • Johan Meuller
  • Johan Cassel
  • Gabrielle Saarinen
  • Zhong-Qing Yuan
  • Christian Löfberg
  • Staffan Karlsson
  • Monica Sundqvist
  • Carl Whatling
  • J. Med. Chem..2019 05;62(9):4325-4349. doi: 10.1021/acs.jmedchem.8b02012.Epub 2019-04-15.

前立腺閉塞症良性疾患に対するUNBLOCSランダム化比較試験における前立腺の経尿道的切除術対チュリウムレーザー経尿道的気化切除術のCost-Effectiveness

The Cost-Effectiveness of Transurethral resection of the prostate versus Thulium laser transurethral vaporesection of the prostate in the UNBLOCS randomised controlled trial for benign prostatic obstruction.
  • S M Noble
  • A M Ahern
  • J Worthington
  • H Hashim
  • H Taylor
  • G J Young
  • S Brookes
  • P Abrams
  • L Johnson
  • R Khan
  • T Page
  • S Swami
  • J A Lane
  • BJU Int..2020 Jun;doi: 10.1111/bju.15138.Epub 2020-06-17.

HIV感染者におけるcART開始後の治療変更:ドイツClinSurv HIVコホート2005-2017のレトロスペクティブ分析

Treatment modification after starting cART in people living with HIV: retrospective analysis of the German ClinSurv HIV Cohort 2005-2017.
  • Melanie Stecher
  • Philipp Schommers
  • Christian Kollan
  • Matthias Stoll
  • Frieder Kuhlendahl
  • Hans-Jürgen Stellbrink
  • Jan-Christian Wasmuth
  • Christoph Stephan
  • Laura Hamacher
  • Clara Lehmann
  • Christoph Boesecke
  • Johannes Bogner
  • Stefan Esser
  • Carlos Fritzsche
  • Annette Haberl
  • Christian Hoffmann
  • Björn Jensen
  • Carolynne Schwarze-Zander
  • Martin Platten
  • Gerd Fätkenheuer
  • Daniel Schmidt
  • Barbara Gunsenheimer-Bartmeyer
  • Jörg Janne Vehreschild
  • Infection.2020 Jul;10.1007/s15010-020-01469-6. doi: 10.1007/s15010-020-01469-6.Epub 2020-07-01.

Toll-like Receptor 4 (TLR4)の遮断は、高グルコースに曝露されたライディッヒ細胞において酸化ストレスを軽減し、phospho-ERK1/2レベルを回復させます

Blockade of Toll-like receptor 4 (TLR4) reduces oxidative stress and restores phospho-ERK1/2 levels in Leydig cells exposed to high glucose.
  • Tatiana Karpova
  • Amanda Almeida de Oliveira
  • Huda Naas
  • Fernanda Priviero
  • Kenia Pedrosa Nunes
  • Life Sci..2020 Mar;245:117365. S0024-3205(20)30112-0. doi: 10.1016/j.lfs.2020.117365.Epub 2020-01-27.

フェニル-2,4,6-トリメチルベンゾイルホスフィン酸リチウムで光重合したゼラチンメタクリロイル系ハイドロゲルのヒト初代腎近位尿細管上皮細胞における毒性と光増感性の評価

Toxicity and photosensitizing assessment of gelatin methacryloyl-based hydrogels photoinitiated with lithium phenyl-2,4,6-trimethylbenzoylphosphinate in human primary renal proximal tubule epithelial cells.
  • Alexander K Nguyen
  • Peter L Goering
  • Vytas Reipa
  • Roger J Narayan
  • Biointerphases.2019 05;14(2):021007. doi: 10.1116/1.5095886.Epub 2019-05-03.

腫瘍細胞株のプロテオーム活性のランドスケープが薬物反応を決定する

Proteome activity landscapes of tumor cell lines determine drug responses.
  • Martin Frejno
  • Chen Meng
  • Benjamin Ruprecht
  • Thomas Oellerich
  • Sebastian Scheich
  • Karin Kleigrewe
  • Enken Drecoll
  • Patroklos Samaras
  • Alexander Hogrebe
  • Dominic Helm
  • Julia Mergner
  • Jana Zecha
  • Stephanie Heinzlmeir
  • Mathias Wilhelm
  • Julia Dorn
  • Hans-Michael Kvasnicka
  • Hubert Serve
  • Wilko Weichert
  • Bernhard Kuster
  • Nat Commun.2020 Jul;11(1):3639. 10.1038/s41467-020-17336-9. doi: 10.1038/s41467-020-17336-9.Epub 2020-07-20.

プロテオームとタンパク質のリン酸化の変化は、ポプラ植物のカドミウム毒性を緩和するための外因性窒素の保護的役割を明らかにした

Changes in Proteome and Protein Phosphorylation Reveal the Protective Roles of Exogenous Nitrogen in Alleviating Cadmium Toxicity in Poplar Plants.
  • Jinliang Huang
  • Xiaolu Wu
  • Feifei Tian
  • Qi Chen
  • Pengrui Luo
  • Fan Zhang
  • Xueqin Wan
  • Yu Zhong
  • Qinglin Liu
  • Tiantian Lin
  • Int J Mol Sci.2019 Dec;21(1). E278. doi: 10.3390/ijms21010278.Epub 2019-12-31.

アフリカにおける COVID-19 パンデミック時の定期的な小児予防接種:SARS-CoV-2 感染の過剰リスクと健康上の利益の便益リスク分析

Routine childhood immunisation during the COVID-19 pandemic in Africa: a benefit-risk analysis of health benefits versus excess risk of SARS-CoV-2 infection.
  • Kaja Abbas
  • Simon R Procter
  • Kevin van Zandvoort
  • Andrew Clark
  • Sebastian Funk
  • Tewodaj Mengistu
  • Dan Hogan
  • Emily Dansereau
  • Mark Jit
  • Stefan Flasche
  • Lancet Glob Health.2020 Jul;S2214-109X(20)30308-9. doi: 10.1016/S2214-109X(20)30308-9.Epub 2020-07-17.

ポリ(2-ヒドロキシエチルメタクリレート)をベースとした複合非晶質固体分散体。親水性不溶性高分子担体からの薬物放出に関する研究(多孔質化剤の存在下および非存在下での研究

Complex amorphous solid dispersions based on poly(2-hydroxyethyl methacrylate): Study of drug release from a hydrophilic insoluble polymeric carrier in the presence and absence of a porosity increasing agent.
  • Melissa Everaerts
  • Guy Van den Mooter
  • Int J Pharm.2019 Jul;566:77-88. S0378-5173(19)30399-0. doi: 10.1016/j.ijpharm.2019.05.040.Epub 2019-05-16.

孵化したばかりの日本のメダカにおける転写応答は、希釈アスファルト曝露後の発生奇形と関連している

Transcriptional responses in newly-hatched Japanese medaka (Oryzias latipes) associated with developmental malformations following diluted bitumen exposure.
  • Barry N Madison
  • Sarah J Wallace
  • Jing Zhang
  • Peter V Hodson
  • Valerie S Langlois
  • Comp. Biochem. Physiol. Part D Genomics Proteomics.2020 May;35:100685. S1744-117X(20)30032-0. doi: 10.1016/j.cbd.2020.100685.Epub 2020-05-06.

新しい近赤外ハイパースペクトルイメージング(NIR-HSI)法を用いて、水生サンプル中の微小なマイクロプラスチックを迅速かつ直接検出する

Rapid and direct detection of small microplastics in aquatic samples by a new near infrared hyperspectral imaging (NIR-HSI) method.
  • Stefania Piarulli
  • Giorgia Sciutto
  • Paolo Oliveri
  • Cristina Malegori
  • Silvia Prati
  • Rocco Mazzeo
  • Laura Airoldi
  • Chemosphere.2020 Jul;260:127655. S0045-6535(20)31850-6. doi: 10.1016/j.chemosphere.2020.127655.Epub 2020-07-10.

顎関節症を伴う若年性特発性関節炎における疼痛および開口部に対する関節内コルチコステロイド注射の効果。システマティックレビューとメタアナリシス

Effect of intra-articular corticosteroid injections on pain and mouth opening in juvenile idiopathic arthritis with temporomandibular involvement: A systematic review and meta-analysis.
  • Gregory S Antonarakis
  • Adrien Blanc
  • Delphine S Courvoisier
  • Paolo Scolozzi
  • J Craniomaxillofac Surg.2020 Jun;S1010-5182(20)30155-4. doi: 10.1016/j.jcms.2020.06.010.Epub 2020-06-27.

低磁場磁気共鳴イメージングを用いた流体減衰反転回復シーケンス上の酸素誘発性イヌ脳脊髄液の高輝度化の低減のための適切な霊感酸素の割合

Proper fraction of inspired oxygen for reduction of oxygen-induced canine cerebrospinal fluid hyperintensity on fluid attenuation inversion recovery sequence using low-field magnetic resonance imaging.
  • Moonjung Jang
  • Jaewoo Hwang
  • Jihye Nam
  • Dalhae Kim
  • Wongyun Son
  • Inhyung Lee
  • Mincheol Choi
  • Junghee Yoon
  • J. Vet. Med. Sci..2020 Jul;doi: 10.1292/jvms.20-0060.Epub 2020-07-20.

消化管の神経内分泌がんと神経内分泌非神経内分泌混合新生物は予後が同じ?12,878例のデータベース解析

Do neuroendocrine carcinomas and mixed neuroendocrine-non-neuroendocrine neoplasm of the gastrointestinal tract have the same prognosis? A database analysis of 12,878 cases.
  • Huiying Shi
  • Cuihua Qi
  • Lingjun Meng
  • Hailing Yao
  • Chen Jiang
  • Mengke Fan
  • Suya Pang
  • Qin Zhang
  • Rong Lin
  • Ther Adv Endocrinol Metab.2020;11:2042018820938304. 10.1177_2042018820938304. doi: 10.1177/2042018820938304.Epub 2020-07-06.

ヒト免疫不全ウイルスの母子感染予防のための非ヌクレオシド系逆転写抑制剤-高活性抗レトロウイルス療法の効果には治療経験と妊娠の繰り返しが影響する

Treatment Experience and Repeat Pregnancy Impact the Effectiveness of Non-Nucleoside Reverse Transcription Inhibitor-Highly Active Antiretroviral Therapy for the Prevention of Mother to Child Transmission of Human Immunodeficiency Virus.
  • Indira B Martin
  • Stanley Read
  • Richard Harrigan
  • M Perry Gomez
  • AIDS Res. Hum. Retroviruses.2020 Jun;doi: 10.1089/AID.2019.0001.Epub 2020-06-09.

北極・南極海堆積物中のポリ塩化ジベンゾ-p-ダイオキシン類とジベンゾフラン類の前駆体。気候変動に直面した環境問題

Precursors of polychlorinated dibenzo-p-dioxins and dibenzofurans in Arctic and Antarctic marine sediments: Environmental concern in the face of climate change.
  • Marta Ewelina Kobusińska
  • Krzysztof Konrad Lewandowski
  • Anna Panasiuk
  • Leszek Łęczyński
  • Magdalena Urbaniak
  • Tadeusz Ossowski
  • Elżbieta Niemirycz
  • Chemosphere.2020 Jul;260:127605. S0045-6535(20)31800-2. doi: 10.1016/j.chemosphere.2020.127605.Epub 2020-07-10.

酵母を用いたスクリーニングにより、ニーマンピック病タイプCで影響を受ける細胞経路が明らかになった

Unbiased yeast screens identify cellular pathways affected in Niemann-Pick disease type C.
  • Alexandria Colaco
  • María E Fernández-Suárez
  • Dawn Shepherd
  • Lihi Gal
  • Chen Bibi
  • Silvia Chuartzman
  • Alan Diot
  • Karl Morten
  • Emily Eden
  • Forbes D Porter
  • Joanna Poulton
  • Nick Platt
  • Maya Schuldiner
  • Frances M Platt
  • Life Sci Alliance.2020 Jul;3(7). e201800253. doi: 10.26508/lsa.201800253.Epub 2020-06-02.

全ゲノムシークエンシングにより解決された進行性偽リウマチ性異形成:WISP3の新規変異と文献のレビュー

Progressive Pseudorheumatoid Dysplasia resolved by whole exome sequencing: a novel mutation in WISP3 and review of the literature.
  • Ben Pode-Shakked
  • Asaf Vivante
  • Ortal Barel
  • Shai Padeh
  • Dina Marek-Yagel
  • Alvit Veber
  • Shachar Abudi
  • Aviva Eliyahu
  • Irit Tirosh
  • Shiri Shpilman
  • Shirlee Shril
  • Friedhelm Hildebrandt
  • Mordechai Shohat
  • Yair Anikster
  • BMC Med. Genet..2019 03;20(1):53. 10.1186/s12881-019-0787-x. doi: 10.1186/s12881-019-0787-x.Epub 2019-03-29.

Intrigue.イマチニブ後の進行性消化管間質腫瘍を対象としたリプレチニブ対スニチニブの第III相試験

Intrigue: Phase III study of ripretinib versus sunitinib in advanced gastrointestinal stromal tumor after imatinib.
  • John Nemunaitis
  • Sebastian Bauer
  • Jean-Yves Blay
  • Khalil Choucair
  • Hans Gelderblom
  • Suzanne George
  • Patrick Schöffski
  • Margaret von Mehren
  • John Zalcberg
  • Haroun Achour
  • Rodrigo Ruiz-Soto
  • Michael C Heinrich
  • Future Oncol.2020 Jan;16(1):4251-4264. doi: 10.2217/fon-2019-0633.Epub 2019-11-22.

ターンオーバー、ミネラル化、体積分類の潜在的バイオマーカー。血液透析患者におけるNMRメタボロミクスを用いた結果.

Potential Biomarkers of the Turnover, Mineralization, and Volume Classification: Results Using NMR Metabolomics in Hemodialysis Patients.
  • Aline L Baptista
  • Kallyandra Padilha
  • Pamella A Malagrino
  • Gabriela Venturini
  • Ana Cm Zeri
  • Luciene M Dos Reis
  • Janaina S Martins
  • Vanda Jorgetti
  • Alexandre C Pereira
  • Silvia M Titan
  • Rosa Ma Moyses
  • JBMR Plus.2020 Jul;4(7):e10372. JBM410372. doi: 10.1002/jbm4.10372.Epub 2020-05-27.

重複する臨床病理学的特徴を有する赤色染料による遅延性タトゥー反応。高周波超音波および線間光干渉断層撮影による検査

Delayed Tattoo Reaction From Red Dye With Overlapping Clinicopathological Features: Examination With High-Frequency Ultrasound and Line-Field Optical Coherence Tomography.
  • Linda Tognetti
  • Sean Ekinde
  • Cyril Habougit
  • Elisa Cinotti
  • Pietro Rubegni
  • Jean Luc Perrot
  • Dermatol Pract Concept.2020 Jul;10(3):e2020053. dp1003a53. doi: 10.5826/dpc.1003a53.Epub 2020-06-29.

健康活動プログラムの効果の持続性と費用対効果:プライマリケアでのカウンセラーによるうつ病の短期心理治療:無作為化比較試験の12ヶ月間の追跡調査

Sustained effectiveness and cost-effectiveness of the Healthy Activity Programme, a brief psychological treatment for depression delivered by lay counsellors in primary care: 12-month follow-up of a randomised controlled trial.
  • Benedict Weobong
  • Helen A Weiss
  • David McDaid
  • Daisy R Singla
  • Steven D Hollon
  • Abhijit Nadkarni
  • A-La Park
  • Bhargav Bhat
  • Basavraj Katti
  • Arpita Anand
  • Sona Dimidjian
  • Ricardo Araya
  • Michael King
  • Lakshmi Vijayakumar
  • G Terence Wilson
  • Richard Velleman
  • Betty R Kirkwood
  • Christopher G Fairburn
  • Vikram Patel
  • PLoS Med..2017 Sep;14(9):e1002385. PMEDICINE-D-17-01349. doi: 10.1371/journal.pmed.1002385.Epub 2017-09-12.

ニンジン(Daucus carota)における2つのζ-カロテンデサチュラーゼパラログの役割の違い。ZDS1 は、植物の発生とカロテノイド合成に不可欠な機能性遺伝子です

Differential role of the two ζ-carotene desaturase paralogs in carrot (Daucus carota): ZDS1 is a functional gene essential for plant development and carotenoid synthesis.
  • Carlos Flores-Ortiz
  • Lilia M Alvarez
  • Alejandro Undurraga
  • Daniela Arias
  • Felipe Durán
  • Guillermo Wegener
  • Claudia Stange
  • Plant Sci..2020 Feb;291:110327. S0168-9452(19)31500-6. doi: 10.1016/j.plantsci.2019.110327.Epub 2019-11-26.

角膜内皮再生のための生分解性および生体適合性のあるポリエチレングリコールベースのハイドロゲルフィルム

Biodegradable and biocompatible poly(ethylene glycol)-based hydrogel films for the regeneration of corneal endothelium.
  • Berkay Ozcelik
  • Karl D Brown
  • Anton Blencowe
  • Katharina Ladewig
  • Geoffrey W Stevens
  • Jean-Pierre Y Scheerlinck
  • Keren Abberton
  • Mark Daniell
  • Greg G Qiao
  • Adv Healthc Mater.2014 Sep;3(9):1496-507. doi: 10.1002/adhm.201400045.Epub 2014-03-20.