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日本語AIでPubMedを検索

日本語AIでPubMedを検索

PubMedの提供する医学論文データベースを日本語で検索できます。AI(Deep Learning)を活用した機械翻訳エンジンにより、精度高く日本語へ翻訳された論文をご参照いただけます。

みんなが読んでいる論文

サイトカイン放出症候群(CRS)の文脈での IL-6 血清レベルと CAR-T 細胞特異的デジタル PCR の解析

Analysis of IL-6 serum levels and CAR-T cell specific digital PCR in the context of cytokine release syndrome (CRS).
  • Thomas Pabst
  • Raphael Joncourt
  • Evgenii Shumilov
  • Alexander Heini
  • Gertrud Wiedemann
  • Myriam Legros
  • Katja Seipel
  • Christof Schild
  • Katarzyna Jalowiec
  • Behrouz Mansouri
  • Michaela Fux
  • Urban Novak
  • Naomi Porret
  • Sacha Zeerleder
  • Ulrike Bacher
  • Exp. Hematol..2020 Jul;S0301-472X(20)30268-X. doi: 10.1016/j.exphem.2020.07.003.Epub 2020-07-13.

開業医によるCoViD-19患者の在宅管理を支援するためのテレビ電話相談:マルケ州のいくつかの自治体での結果

[The televideoconsultation in support of home management of the patient with CoViD-19 by general practitioner: the results in some municipalities of the Marche Region.]
  • Pierpaolo Morosini
  • Nando Campanella
  • Gina Lucci
  • Amedeo Giorgetti
  • Vanni Lorenzetti
  • Ercolano Manfrini
  • Alfredo Moretti
  • Recenti Prog Med.2020 Jul-Aug;111(7):454-460. doi: 10.1701/3407.33927.

急性前骨髄球性白血病患者に全トランスレチノイン酸と化学療法を施行した場合,最初の連結後に測定可能な残存病変が予後を予測する.

Measurable residual disease after the first consolidation predicts the outcomes of patients with acute promyelocytic leukemia treated with all-trans retinoic acid and chemotherapy.
  • Hideho Henzan
  • Ken Takase
  • Tomohiko Kamimura
  • Yasuo Mori
  • Goichi Yoshimoto
  • Hiromi Iwasaki
  • Koji Nagafuji
  • Ryosuke Ogawa
  • Tetsuya Eto
  • Naoyuki Uchida
  • Tomoaki Fujisaki
  • Koji Kato
  • Mariko Minami
  • Yoshikane Kikushige
  • Koichi Akashi
  • Toshihiro Miyamoto
  • Int. J. Hematol..2020 Jun;10.1007/s12185-020-02911-z. doi: 10.1007/s12185-020-02911-z.Epub 2020-06-10.

エクソンスキップ機構の翻訳後制御が白血病の異常スプライシングを制御していることを明らかにした

Posttranslational regulation of the exon skipping machinery controls aberrant splicing in leukemia.
  • Yalu Zhou
  • Cuijuan Han
  • Eric Wang
  • Adam H Lorch
  • Valentina Serafin
  • Byoung-Kyu Cho
  • Blanca T Guttierrez Diaz
  • Julien Calvo
  • Celestia Fang
  • Alireza Khodadadi-Jamayran
  • Tommaso Tabaglio
  • Christian Marier
  • Anna Kuchmiy
  • Limin Sun
  • George Yacu
  • Szymon K Filip
  • Qi Jin
  • Yoh-Hei Takahashi
  • David R Amici
  • Emily J Rendleman
  • Radhika Rawat
  • Silvia Bresolin
  • Maddalena Paganin
  • Cheng Zhang
  • Hu Li
  • Irawati Kandela
  • Yuliya Politanska
  • Hiam Abdala-Valencia
  • Marc L Mendillo
  • Ping Zhu
  • Bruno Palhais
  • Pieter Van Vlierberghe
  • Tom Taghon
  • Iannis Aifantis
  • Young Ah Goo
  • Ernesto Guccione
  • Adriana Heguy
  • Aristotelis Tsirigos
  • Keng Boon Wee
  • Rama K Mishra
  • Francoise Pflumio
  • Benedetta Accordi
  • Giuseppe Basso
  • Panagiotis Ntziachristos
  • Cancer Discov.2020 May;CD-19-1436. doi: 10.1158/2159-8290.CD-19-1436.Epub 2020-05-22.

遠隔虚血性プリコンディショニングは、非アシル化グレリンによるJAK/STAT経路の活性化を介して心筋虚血再灌流傷害を軽減する

Remote ischemic preconditioning reduces myocardial ischemia-reperfusion injury through unacylated ghrelin-induced activation of the JAK/STAT pathway.
  • Yasuaki Sawashita
  • Naoyuki Hirata
  • Yusuke Yoshikawa
  • Hirofumi Terada
  • Yasuyuki Tokinaga
  • Michiaki Yamakage
  • Basic Res. Cardiol..2020 Jun;115(4):50. 10.1007/s00395-020-0809-z. doi: 10.1007/s00395-020-0809-z.Epub 2020-06-30.

HIV感染症を持つ抗レトロウイルス剤を服用していない妊婦を対象としたRaltegravirとefavirenzの比較試験(NICHD P1081):非盲検、無作為化、対照、第4相試験

Raltegravir versus efavirenz in antiretroviral-naive pregnant women living with HIV (NICHD P1081): an open-label, randomised, controlled, phase 4 trial.
  • Esaú C João
  • R Leavitt Morrison
  • David E Shapiro
  • Nahida Chakhtoura
  • Maria Isabel S Gouvèa
  • Maria de Lourdes B Teixeira
  • Trevon L Fuller
  • Blandina T Mmbaga
  • James S Ngocho
  • Boniface N Njau
  • Avy Violari
  • Ruth Mathiba
  • Zaakirah Essack
  • Jose Henrique S Pilotto
  • Luis Felipe Moreira
  • Maria Jose Rolon
  • Pedro Cahn
  • Sinart Prommas
  • Timothy R Cressey
  • Kulkanya Chokephaibulkit
  • Peerawong Werarak
  • Lauren Laimon
  • Roslyn Hennessy
  • Lisa M Frenkel
  • Patricia Anthony
  • Brookie M Best
  • George K Siberry
  • Mark Mirochnick
  • Lancet HIV.2020 May;7(5):e322-e331. S2352-3018(20)30038-2. doi: 10.1016/S2352-3018(20)30038-2.

アンモニア処理鶏脾臓リンパ球におけるmiR-15aによるアポトーシスとミトコンドリア経路を介した酸化ストレスの発生にNF-κB経路が関与していることを明らかにしました

NF-κB pathway took part in the development of apoptosis mediated by miR-15a and oxidative stress via mitochondrial pathway in ammonia-treated chicken splenic lymphocytes.
  • Dechun Chen
  • Fangyong Ning
  • Jingyang Zhang
  • You Tang
  • Xiaohua Teng
  • Sci. Total Environ..2020 Aug;729:139017. S0048-9697(20)32534-1. doi: 10.1016/j.scitotenv.2020.139017.Epub 2020-04-26.

肝硬変誘発性肝性脳症に対するホスファチジルセリンの効果。肝硬変ラットにおける急性エンドトキシン血症への反応

Effect of phosphatidylserine on cirrhosis-induced hepatic encephalopathy: Response to acute endotoxemia in cirrhotic rats.
  • Golnaz Zamanian
  • Alireza Partoazar
  • Seyed Mohammad Tavangar
  • Amir Rashidian
  • Parto Mirzaei
  • Qamar Niaz
  • Khadijeh Sharifi
  • Ahmad Reza Dehpour
  • Farahnaz Jazaeri
  • Life Sci..2020 Jul;253:117606. S0024-3205(20)30354-4. doi: 10.1016/j.lfs.2020.117606.Epub 2020-04-19.

リツキシマブによる治療後の体液性免疫不全を有する B 細胞非ホジキンリンパ腫患者における 20%皮下免疫グロブリン補充療法の使用

The Use of 20% Subcutaneous Immunoglobulin Replacement Therapy in Patients With B Cell Non-Hodgkin Lymphoma With Humoral Immune Dysfunction After Treatment With Rituximab.
  • S Shahzad Mustafa
  • Saad Jamshed
  • Karthik Vadamalai
  • Allison Ramsey
  • Clin Lymphoma Myeloma Leuk.2020 May;S2152-2650(20)30184-1. doi: 10.1016/j.clml.2020.04.006.Epub 2020-05-08.

アジアン酸はAMPK/PI3K/AKTシグナル伝達経路を介して関節軟骨細胞の肥大と線維化分化を減衰させる

Asiatic acid attenuates hypertrophic and fibrotic differentiation of articular chondrocytes via AMPK/PI3K/AKT signaling pathway.
  • Na Liu
  • Dejie Fu
  • Junjun Yang
  • Pingju Liu
  • Xiongbo Song
  • Xin Wang
  • Rui Li
  • Zhenlan Fu
  • Jiajia Chen
  • Xiaoyuan Gong
  • Cheng Chen
  • Liu Yang
  • Arthritis Res. Ther..2020 05;22(1):112. 10.1186/s13075-020-02193-0. doi: 10.1186/s13075-020-02193-0.Epub 2020-05-12.

犬の創傷治癒に対するアマゾン植物由来の植物性医薬品の有効性

Efficacy of Phytopharmaceuticals From the Amazonian Plant for Wound Healing in Dogs.
  • Ádria Vanessa Linhares Dos Santos Américo
  • Kariane Mendes Nunes
  • Francisco Flávio Vieira de Assis
  • Salatiel Ribeiro Dias
  • Carla Tatiane Seixas Passos
  • Adriana Caroprezo Morini
  • Junior Avelino de Araújo
  • Kelly Christina Ferreira Castro
  • Silvia Katrine Rabelo da Silva
  • Lauro Euclides Soares Barata
  • Antonio Humberto Hamad Minervino
  • Front Vet Sci.2020;7:244. doi: 10.3389/fvets.2020.00244.Epub 2020-06-12.

骨髄間質細胞由来のmicroRNA-181含有細胞外小胞は、Wnt/β-カテニンシグナル伝達経路を介してMESTをダウンレギュレートすることで、卵巣癌細胞の化学抵抗性を抑制する

Bone marrow stromal cells-derived microRNA-181-containing extracellular vesicles inhibit ovarian cancer cell chemoresistance by downregulating MEST via the Wnt/β-catenin signaling pathway.
  • Zhengyi Ruan
  • Lili Lu
  • Li Zhang
  • Min Dong
  • Cancer Gene Ther..2020 Jul;10.1038/s41417-020-0195-6. doi: 10.1038/s41417-020-0195-6.Epub 2020-07-07.

二次性進行性多発性硬化症(MS-SMART)における3種類の神経保護薬の有効性:第2b相、多群、二重盲検、無作為化プラセボ対照試験

Efficacy of three neuroprotective drugs in secondary progressive multiple sclerosis (MS-SMART): a phase 2b, multiarm, double-blind, randomised placebo-controlled trial.
  • Jeremy Chataway
  • Floriana De Angelis
  • Peter Connick
  • Richard A Parker
  • Domenico Plantone
  • Anisha Doshi
  • Nevin John
  • Jonathan Stutters
  • David MacManus
  • Ferran Prados Carrasco
  • Frederik Barkhof
  • Sebastien Ourselin
  • Marie Braisher
  • Moira Ross
  • Gina Cranswick
  • Sue H Pavitt
  • Gavin Giovannoni
  • Claudia Angela Gandini Wheeler-Kingshott
  • Clive Hawkins
  • Basil Sharrack
  • Roger Bastow
  • Christopher J Weir
  • Nigel Stallard
  • Siddharthan Chandran
  • Lancet Neurol.2020 03;19(3):214-225. S1474-4422(19)30485-5. doi: 10.1016/S1474-4422(19)30485-5.Epub 2020-01-22.

シロチョウザメ(Acipenser transmontanus)のアリール炭化水素受容体核内トランスロケータ(ARNT1, ARNT2, ARNT3)。その配列、組織特異的発現、β-ナフトフラボンに対する応答

Aryl hydrocarbon receptor nuclear translocators (ARNT1, ARNT2, and ARNT3) of white sturgeon (Acipenser transmontanus): Sequences, tissue-specific expressions, and response to β-naphthoflavone.
  • Jon A Doering
  • Shawn C Beitel
  • Sarah Patterson
  • Bryanna K Eisner
  • John P Giesy
  • Markus Hecker
  • Steve Wiseman
  • Comp. Biochem. Physiol. C Toxicol. Pharmacol..2020 May;231:108726. S1532-0456(20)30026-0. doi: 10.1016/j.cbpc.2020.108726.Epub 2020-02-17.

環境に関連したベンゾアピレンへの短期の水性曝露に対する雄と雌のファットヘッドミノー(Pimephales promelas)の腸内細菌叢の応答の違い

Differential responses of gut microbiota of male and female fathead minnow (Pimephales promelas) to a short-term environmentally-relevant, aqueous exposure to benzo[a]pyrene.
  • Abigail DeBofsky
  • Yuwei Xie
  • Chelsea Grimard
  • Alper James Alcaraz
  • Markus Brinkmann
  • Markus Hecker
  • John P Giesy
  • Chemosphere.2020 Aug;252:126461. S0045-6535(20)30654-8. doi: 10.1016/j.chemosphere.2020.126461.Epub 2020-03-12.

β-ナフトフラボンに曝露したヒト初代ケラチノサイトの時間的トランスクリプトーム解析から、環境汚染物質に対する皮膚の保護効果が明らかになった

Temporal transcriptomic analysis of human primary keratinocytes exposed to β-naphthoflavone highlights the protective efficacy of skin to environmental pollutants.
  • Paul Quantin
  • Angela Patatian
  • Maxime Floreani
  • Christophe Egles
  • Philippe Benech
  • Hervé Ficheux
  • Toxicol In Vitro.2020 Jun;65:104822. S0887-2333(19)30857-4. doi: 10.1016/j.tiv.2020.104822.Epub 2020-03-06.

2,3,4,5,6-ペンタフルオロベンジルブロマイド誘導体化とガスクロマトグラフィー質量分析による水中の7つのパーフルオロアルキルカルボン酸の同時測定

Simultaneous determination of seven perfluoroalkyl carboxylic acids in water samples by 2,3,4,5,6-pentafluorobenzyl bromide derivatization and gas chromatography-mass spectrometry.
  • Yongyan Ji
  • Zongyan Cui
  • Zhibin Wang
  • Yanzhong Cao
  • Xuemin Li
  • Adan Li
  • Environ. Pollut..2020 Jun;266(Pt 3):115043. S0269-7491(19)33751-0. doi: 10.1016/j.envpol.2020.115043.Epub 2020-06-21.

頸部前膜および/または側方脊柱管狭窄症を原因とする頸部脊椎症性橈骨症を対象とした後頸部経皮内視鏡的腹側骨減圧療法と単純背側骨減圧療法の比較検討:臨床レトロスペクティブ研究

A comparison study of posterior cervical percutaneous endoscopic ventral bony decompression and simple dorsal decompression treatment in cervical spondylotic radiculopathy caused by cervical foraminal and/or lateral spinal stenosis: a clinical retrospective study.
  • Yuexin Tong
  • Zhangheng Huang
  • Chuan Hu
  • Zhiyi Fan
  • Fucheng Bian
  • Fengkai Yang
  • Chengliang Zhao
  • BMC Musculoskelet Disord.2020 May;21(1):290. 10.1186/s12891-020-03313-2. doi: 10.1186/s12891-020-03313-2.Epub 2020-05-11.

ジアゼパム、メトホルミン、オメプラゾール、シムバスタチン:個々の急性毒性と混合物の急性毒性の完全な議論

Diazepam, metformin, omeprazole and simvastatin: a full discussion of individual and mixture acute toxicity.
  • Raquel Sampaio Jacob
  • Lucilaine Valéria de Souza Santos
  • Mirna d'Auriol
  • Yuri Abner Rocha Lebron
  • Victor Rezende Moreira
  • Liséte Celina Lange
  • Ecotoxicology.2020 Jun;10.1007/s10646-020-02239-8. doi: 10.1007/s10646-020-02239-8.Epub 2020-06-25.

慢性的なセロトニン再取り込み阻害は、過食ラットにおいて褐色脂肪のミトコンドリアの結合を解除し、白色脂肪の褐変/褐変過程を誘導する

Chronic serotonin reuptake inhibition uncouples brown fat mitochondria and induces beiging/browning process of white fat in overfed rats.
  • Glauber Rudá F Braz
  • Aline Isabel da Silva
  • Severina Cássia A Silva
  • Anderson Apolonio S Pedroza
  • Maria Daniele T B de Lemos
  • Flávia Ariane S de Lima
  • Tercya Lúcidi A Silva
  • Claudia Jacques Lagranha
  • Life Sci..2020 Mar;245:117307. S0024-3205(20)30054-0. doi: 10.1016/j.lfs.2020.117307.Epub 2020-01-16.

びまん性大細胞型B細胞リンパ腫におけるCHOP治療における抗アポトーシスBCL-2ファミリー蛋白質への依存性の異質パターン

Heterogeneous Pattern of Dependence on Anti-Apoptotic BCL-2 Family Proteins upon CHOP Treatment in Diffuse Large B-Cell Lymphoma.
  • Mathilde Rikje Willemijn de Jong
  • Myra Langendonk
  • Bart Reitsma
  • Marcel Nijland
  • Anke van den Berg
  • Emanuele Ammatuna
  • Lydia Visser
  • Tom van Meerten
  • Int J Mol Sci.2019 Nov;20(23). E6036. doi: 10.3390/ijms20236036.Epub 2019-11-30.

ラットにおけるインドメタシン誘発性胃傷害に対する胃保護のための最適化されたエラグ酸-Caペクチネート浮遊ビーズ

Optimized Ellagic Acid-Ca Pectinate Floating Beads for Gastroprotection against Indomethacin-Induced Gastric Injury in Rats.
  • Nabil A Alhakamy
  • Shaimaa M Badr-Eldin
  • Osama A A Ahmed
  • Abdulrahman A Halwani
  • Hibah M Aldawsari
  • Mohamed A El-Moselhy
  • Aliaa Anter
  • Sara S Sharkawi
  • Muhammad H Sultan
  • Osama A A Madkhali
  • Muhammed A Bakhrebah
  • Mohammad N Alomary
  • Wesam H Abdulaal
  • Usama A Fahmy
  • Biomolecules.2020 Jul;10(7). E1006. doi: 10.3390/biom10071006.Epub 2020-07-06.

ストロングハート研究およびストロングハートファミリー研究における母親のヒ素曝露と成人の空腹時血糖値およびインスリン抵抗性との関連

Associations of maternal arsenic exposure with adult fasting glucose and insulin resistance in the Strong Heart Study and Strong Heart Family Study.
  • Naomi E Tinkelman
  • Miranda Jones Spratlen
  • Arce Domingo-Relloso
  • Maria Tellez-Plaza
  • Maria Grau-Perez
  • Kevin A Francesconi
  • Walter Goessler
  • Barbara V Howard
  • Jean MacCluer
  • Kari E North
  • Jason G Umans
  • Pam Factor-Litvak
  • Shelley A Cole
  • Ana Navas-Acien
  • Environ Int.2020 Apr;137:105531. S0160-4120(19)32611-X. doi: 10.1016/j.envint.2020.105531.Epub 2020-02-18.

変異型SOD1マウスの脳幹の単細胞RNA-seq解析により、筋萎縮性側索硬化症の細胞型と経路が変化していることが明らかになった

Single-cell RNA-seq analysis of the brainstem of mutant SOD1 mice reveals perturbed cell types and pathways of amyotrophic lateral sclerosis.
  • Wenting Liu
  • Sharmila Venugopal
  • Sana Majid
  • In Sook Ahn
  • Graciel Diamante
  • Jason Hong
  • Xia Yang
  • Scott H Chandler
  • Neurobiol. Dis..2020 Jul;141:104877. S0969-9961(20)30152-2. doi: 10.1016/j.nbd.2020.104877.Epub 2020-04-30.

慢性拘縮性心膜炎患者におけるガレクチン-3レベル

Galectin-3 Levels in Patients with Chronic Constrictive Pericarditis.
  • Fábio Fernandes
  • Dirceu Thiago Pessoa de Melo
  • Felix José Alvarez Ramires
  • Ester Cerdeira Sabino
  • Carlos Henrique Valente Moreira
  • Luiz Alberto Benvenutti
  • Viviane Tiemi Hotta
  • Ana Luiza Carrari Sayegh
  • Francis Ribeiro de Souza
  • Ricardo Ribeiro Dias
  • Charles Mady
  • Arq. Bras. Cardiol..2020 04;114(4):683-689. S0066-782X2020000400683. doi: 10.36660/abc.20190152.Epub 2020-05-29.