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日本語AIでPubMedを検索

日本語AIでPubMedを検索

PubMedの提供する医学論文データベースを日本語で検索できます。AI(Deep Learning)を活用した機械翻訳エンジンにより、精度高く日本語へ翻訳された論文をご参照いただけます。

みんなが読んでいる論文

マキノフェノール抽出物は、PKC-αシグナル伝達経路を調節し、鉛(II)暴露マウスの小胞体ストレスを減少させることにより、肝機能を維持することが示された

Malus micromalus Makino phenolic extract preserves hepatorenal function by regulating PKC-α signaling pathway and attenuating endoplasmic reticulum stress in lead (II) exposure mice.
  • Guangliang Wang
  • Jinlei Tang
  • Qi Song
  • Qianqian Yu
  • Congying Yao
  • Pengfei Li
  • Yixin Ding
  • Mibin Lin
  • Dai Cheng
  • J. Inorg. Biochem..2020 02;203:110925. S0162-0134(19)30536-7. doi: 10.1016/j.jinorgbio.2019.110925.Epub 2019-11-14.

植物化学物質インディカキサンチンは、酸化ストレス依存性のp53/p21軸を介してHeLa細胞におけるシスプラチン誘発性アポトーシスを相乗的に増強する

The Phytochemical Indicaxanthin Synergistically Enhances Cisplatin-Induced Apoptosis in HeLa Cells via Oxidative Stress-Dependent p53/p21 Axis.
  • Mario Allegra
  • Antonella D'Anneo
  • Anna Frazzitta
  • Ignazio Restivo
  • Maria Antonia Livrea
  • Alessandro Attanzio
  • Luisa Tesoriere
  • Biomolecules.2020 Jul;10(7). E994. doi: 10.3390/biom10070994.Epub 2020-07-02.

メタボリックシンドロームとバターやケルマンシャーギーを含む乳由来の油の消費との関係。Ravansar非伝染性疾患コホート研究

Relationship Between the Consumption of Milk-Based Oils Including Butter and Kermanshah Ghee with Metabolic Syndrome: Ravansar Non-Communicable Disease Cohort Study.
  • Elham Ahmadi
  • Hadi Abdollahzad
  • Yahya Pasdar
  • Shahab Rezaeian
  • Jalal Moludi
  • Seyed Mostafa Nachvak
  • Roghayeh Mostafai
  • Diabetes Metab Syndr Obes.2020;13:1519-1530. 247412. doi: 10.2147/DMSO.S247412.Epub 2020-05-05.

新しい大気圧イオン化プローブ(UniSpray™)を用いたLC-MS/MSによる静脈全血からの免疫抑制剤の定量のための体積吸収型マイクロサンプリング(VAMS)

Volumetric Absorptive Microsampling (VAMS) for assaying immunosuppressants from venous whole blood by LC-MS/MS using a novel atmospheric pressure ionization probe (UniSpray™).
  • Lucía Paniagua-González
  • Carla Díaz-Louzao
  • Elena Lendoiro
  • Esteban Otero-Antón
  • Carmen Cadarso-Suárez
  • Manuel López-Rivadulla
  • Angelines Cruz
  • Ana de-Castro-Ríos
  • J Pharm Biomed Anal.2020 Jun;189:113422. S0731-7085(20)31308-X. doi: 10.1016/j.jpba.2020.113422.Epub 2020-06-12.

プロトンポンプ阻害剤パントプラゾールの腎臓・肝臓移植患者のマイコフェノール酸曝露に対する効果(IMPACT試験):無作為化試験

Effect of the proton-pump Inhibitor pantoprazole on MycoPhenolic ACid exposure in kidney and liver transplant recipienTs (IMPACT study): a randomized trial.
  • Andrew Sunderland
  • Graeme Russ
  • Benedetta Sallustio
  • Matthew Cervelli
  • David Joyce
  • Esther Ooi
  • Gary Jeffrey
  • Neil Boudville
  • Aron Chakera
  • Gursharan Dogra
  • Doris Chan
  • Germaine Wong
  • Wai H Lim
  • Nephrol. Dial. Transplant..2020 Jun;35(6):1060-1070. 5855235. doi: 10.1093/ndt/gfaa111.

ユビキチン特異的プロテアーゼ12および13によるH2Aub1の除去は、シロイヌナズナにおいてポリコムを介した安定な遺伝子抑制に必要であることを明らかにした

Removal of H2Aub1 by ubiquitin-specific proteases 12 and 13 is required for stable Polycomb-mediated gene repression in Arabidopsis.
  • Lejon E M Kralemann
  • Shujing Liu
  • Minerva S Trejo-Arellano
  • Rafael Muñoz-Viana
  • Claudia Köhler
  • Lars Hennig
  • Genome Biol..2020 Jun;21(1):144. 10.1186/s13059-020-02062-8. doi: 10.1186/s13059-020-02062-8.Epub 2020-06-16.

von Willebrand factorの大きなインフレーム欠失の特徴を明らかにすることで、異なる発症機序が明らかになった

Characterization of large in-frame von Willebrand factor deletions highlights differing pathogenic mechanisms.
  • Ashley Cartwright
  • Simon J Webster
  • Annika de Jong
  • Richard J Dirven
  • Lisa D S Bloomer
  • Ahlam M Al-Buhairan
  • Ulrich Budde
  • Christer Halldén
  • David Habart
  • Jenny Goudemand
  • Ian R Peake
  • Jeroen C J Eikenboom
  • Anne C Goodeve
  • Daniel J Hampshire
  • Blood Adv.2020 Jul;4(13):2979-2990. 461228. doi: 10.1182/bloodadvances.2018027813.

この研究では、分子動力学とドッキングシミュレーションを組み合わせて、hTRPM8チャネル上で最適化されたバーチャルスクリーニングキャンペーンを実行するためのターゲットとなるプロトコルを開発した

Combining Molecular Dynamics and Docking Simulations to Develop Targeted Protocols for Performing Optimized Virtual Screening Campaigns on The hTRPM8 Channel.
  • Carmine Talarico
  • Silvia Gervasoni
  • Candida Manelfi
  • Alessandro Pedretti
  • Giulio Vistoli
  • Andrea R Beccari
  • Int J Mol Sci.2020 Mar;21(7). E2265. doi: 10.3390/ijms21072265.Epub 2020-03-25.

肺移植候補者における在宅ベースのプレハビリテーションプログラム参加中の 6 分間歩行距離の変化-レトロスペクティブなカルテレビュー

Changes in 6-minute walking distance in lung transplant candidates while participating in a home-based pre-habilitation program - A retrospective chart review.
  • Daniela Massierer
  • Nicholas Bourgeois
  • Agnès Räkel
  • Karina Prévost
  • Larry C Lands
  • Charles Poirier
  • Tania Janaudis-Ferreira
  • Clin Transplant.2020 Jul;:e14045. doi: 10.1111/ctr.14045.Epub 2020-07-19.

持続的薬物送達システムとしてのイブプロフェン-メソポーラスハイドロキシアパタイトナノハイブリッドの簡便な合成と特性評価

Facile Synthesis and Characterization of Ibuprofen-mesoporous Hydroxyapatite Nanohybrid as a Sustained Drug Delivery System.
  • Zahra Namazi
  • Tahereh Sadat Jafarzadeh Kashi
  • Mohammad Erfan
  • Farhood Najafi
  • Leila Bakhtiari
  • Seyed Rohola Ghodsi
  • Hassan Farhadnejad
  • Iran J Pharm Res.2019;18(3):1196-1211. doi: 10.22037/ijpr.2019.1100769.

Mitotic checkpoint kinase Mps1/TTKは大腸がん患者の予後を予測し、PKCα/ERK1/2やPI3K/Akt経路を介して腫瘍の増殖や分化を制御しています

Mitotic checkpoint kinase Mps1/TTK predicts prognosis of colon cancer patients and regulates tumor proliferation and differentiation via PKCα/ERK1/2 and PI3K/Akt pathway.
  • Li Zhang
  • Baofei Jiang
  • Ni Zhu
  • Mingyue Tao
  • Yali Jun
  • Xiaofei Chen
  • Qilong Wang
  • Chao Luo
  • Med. Oncol..2019 Nov;37(1):5. 10.1007/s12032-019-1320-y. doi: 10.1007/s12032-019-1320-y.Epub 2019-11-13.

FGFR4は肺腺癌におけるEGFRの癌化シグナルを増加させ、両者の複合的な阻害は高い効果を発揮する

FGFR4 increases EGFR oncogenic signaling in lung adenocarcinoma, and their combined inhibition is highly effective.
  • Alvaro Quintanal-Villalonga
  • Sonia Molina-Pinelo
  • Patricia Yagüe
  • Ángela Marrugal
  • Laura Ojeda-Márquez
  • Rocío Suarez
  • Santiago Ponce-Aix
  • Ana Belén Enguita
  • Amancio Carnero
  • Irene Ferrer
  • Luis Paz-Ares
  • Lung Cancer.2019 05;131:112-121. S0169-5002(19)30323-X. doi: 10.1016/j.lungcan.2019.02.007.Epub 2019-02-08.

枯草菌株NCD-2のPhoR/PhoP二成分系によって制御される多剤耐性を表現型マイクロアレイとトランスクリプトーム解析を用いて明らかにした

Using a phenotype microarray and transcriptome analysis to elucidate multi-drug resistance regulated by the PhoR/PhoP two-component system in Bacillus subtilis strain NCD-2.
  • Qinggang Guo
  • Lihong Dong
  • Peipei Wang
  • Zhenhe Su
  • Xiaomeng Liu
  • Weisong Zhao
  • Xiaoyun Zhang
  • Shezeng Li
  • Xiuyun Lu
  • Ping Ma
  • Microbiol. Res..2020 Jul;239:126557. S0944-5013(20)30425-0. doi: 10.1016/j.micres.2020.126557.Epub 2020-07-13.

最適化された全長 FLT3/CD3 ビスpecific 抗体は、強力な抗白血病活性を示し、可逆的な血液学的毒性を示します

An Optimized Full-Length FLT3/CD3 Bispecific Antibody Demonstrates Potent Anti-leukemia Activity and Reversible Hematological Toxicity.
  • Yik Andy Yeung
  • Veena Krishnamoorthy
  • Danielle Dettling
  • Cesar Sommer
  • Kris Poulsen
  • Irene Ni
  • Amber Pham
  • Wei Chen
  • Sindy Liao-Chan
  • Kevin Lindquist
  • S Michael Chin
  • Allison Given Chunyk
  • Wenyue Hu
  • Barbra Sasu
  • Javier Chaparro-Riggers
  • Ivana Djuretic
  • Mol. Ther..2020 03;28(3):889-900. S1525-0016(20)30009-5. doi: 10.1016/j.ymthe.2019.12.014.Epub 2020-01-14.

ビタミンB12のコバルト中心のニッケルによる置換-金属を含まないB12-リガンドHydrogenobalaminとHydrogenobyric Acidから調製されたニバラミンとニ酪酸

Replacement of the Cobalt-Center of Vitamin B12 by Nickel - Nibalamin and Nibyric Acid Prepared from Metal-Free B12-Ligands Hydrogenobalamin and Hydrogenobyric Acid.
  • Christoph Kieninger
  • Klaus Wurst
  • Maren Podewitz
  • Maria Stanley
  • Evelyne Deery
  • Anrew Lawrence
  • Klaus R Liedl
  • Martin J Warren
  • Bernhard Kräutler
  • Angew. Chem. Int. Ed. Engl..2020 Jul;doi: 10.1002/anie.202008407.Epub 2020-07-20.

クラインフェルター症候群とターナー症候群の統合的な機能ゲノム解析により、X染色体線量変化のグローバルなネットワーク効果が明らかになった

Integrated functional genomic analyses of Klinefelter and Turner syndromes reveal global network effects of altered X chromosome dosage.
  • Xianglong Zhang
  • David Hong
  • Shining Ma
  • Thomas Ward
  • Marcus Ho
  • Reenal Pattni
  • Zhana Duren
  • Atanas Stankov
  • Sharon Bade Shrestha
  • Joachim Hallmayer
  • Wing Hung Wong
  • Allan L Reiss
  • Alexander E Urban
  • Proc. Natl. Acad. Sci. U.S.A..2020 03;117(9):4864-4873. 1910003117. doi: 10.1073/pnas.1910003117.Epub 2020-02-18.

喉頭咽頭逆流症患者の食事の逆流性を評価するスコアの開発

Development of scores assessing the refluxogenic potential of diet of patients with laryngopharyngeal reflux.
  • Jerome R Lechien
  • Francois Bobin
  • Francois Mouawad
  • Karol Zelenik
  • Christian Calvo-Henriquez
  • Carlos M Chiesa-Estomba
  • Necati Enver
  • Andrea Nacci
  • Maria Rosaria Barillari
  • Antonio Schindler
  • Lise Crevier-Buchman
  • Stéphane Hans
  • Virginie Simeone
  • Elzbieta Wlodarczyk
  • Bernard Harmegnies
  • Marc Remacle
  • Alexandra Rodriguez
  • Didier Dequanter
  • Pierre Eisendrath
  • Giovanni Dapri
  • Camille Finck
  • Petros Karkos
  • Hillevi Pendleton
  • Tareck Ayad
  • Vinciane Muls
  • Sven Saussez
  • Eur Arch Otorhinolaryngol.2019 Dec;276(12):3389-3404. 10.1007/s00405-019-05631-1. doi: 10.1007/s00405-019-05631-1.Epub 2019-09-12.

PGC1αはPDHA1とMPC1の発現をアップレギュレーションすることで胆管癌の転移を促進し、Warburg効果を逆転させる

PGC1α promotes cholangiocarcinoma metastasis by upregulating PDHA1 and MPC1 expression to reverse the Warburg effect.
  • Dan Li
  • Chaoqun Wang
  • Panfei Ma
  • Qingan Yu
  • Mingqi Gu
  • Liqian Dong
  • Wenjing Jiang
  • Shangha Pan
  • Changming Xie
  • Jihua Han
  • Yaliang Lan
  • Jing Sun
  • Ping Sheng
  • Kunpeng Liu
  • Yaohua Wu
  • Lianxin Liu
  • Yong Ma
  • Hongchi Jiang
  • Cell Death Dis.2018 05;9(5):466. 10.1038/s41419-018-0494-0. doi: 10.1038/s41419-018-0494-0.Epub 2018-05-01.

非硬直性隔壁静脈血栓症の診断における次世代シーケンシング

Next generation sequencing in the diagnosis of non-cirrhotic splanchnic vein thrombosis.
  • Marta Magaz
  • Alberto Alvarez-Larrán
  • Dolors Colomer
  • Mónica López-Guerra
  • M Ángeles García-Criado
  • Gabriel Mezzano
  • Ernest Belmonte
  • Pol Olivas
  • Guillem Soy
  • Francisco Cervantes
  • Anna Darnell
  • José Ferrusquía-Acosta
  • Anna Baiges
  • Fanny Turon
  • Virginia Hernández-Gea
  • Juan Carlos García-Pagán
  • J. Hepatol..2020 Jul;S0168-8278(20)30456-6. doi: 10.1016/j.jhep.2020.06.045.Epub 2020-07-14.

ヒト誘導多能性幹細胞由来心筋細胞を用いた収縮運動特性に対する薬物誘発効果のビデオベースの評価

Video-based assessment of drug-induced effects on contractile motion properties using human induced pluripotent stem cell-derived cardiomyocytes.
  • Yoshiko Okai
  • Keiko Matsune
  • Kazunori Yamanaka
  • Toshikatsu Matsui
  • Emily Pfeiffer Kaushik
  • Kosuke Harada
  • Hiroshi Kohara
  • Akimitsu Miyawaki
  • Harushige Ozaki
  • Matthew Wagoner
  • Tadahiro Shinozawa
  • J Pharmacol Toxicol Methods.2020 Jul;:106893. S1056-8719(20)30222-7. doi: 10.1016/j.vascn.2020.106893.Epub 2020-07-01.

発酵飼料とワクチン接種と大型ホワイト/ノルウェーランドレース子豚のパラメータに及ぼす影響とその相互作用

Influence of the Fermented Feed and Vaccination and Their Interaction on Parameters of Large White/Norwegian Landrace Piglets.
  • Laurynas Vadopalas
  • Sarunas Badaras
  • Modestas Ruzauskas
  • Vita Lele
  • Vytaute Starkute
  • Paulina Zavistanaviciute
  • Egle Zokaityte
  • Vadims Bartkevics
  • Dovile Klupsaite
  • Erika Mozuriene
  • Agila Dauksiene
  • Sonata Sidlauskiene
  • Romas Gruzauskas
  • Elena Bartkiene
  • Animals (Basel).2020 Jul;10(7). E1201. doi: 10.3390/ani10071201.Epub 2020-07-15.

レドックス活性なテトラチアフルバレン配位子を用いたコバルト金属-有機フレームワークの開発(第2報).MOF内のLLCTの構造と光電気化学的特性への影響

Cobalt Metal-Organic Frameworks Incorporating Redox-Active Tetrathiafulvalene Ligand: Structures and Effect of LLCT within the MOF on Photoelectrochemical Properties.
  • Miao Jiang
  • Yi-Gang Weng
  • Zi-Yao Zhou
  • Chen-Yi Ge
  • Qin-Yu Zhu
  • Jie Dai
  • Inorg Chem.2020 Jul;doi: 10.1021/acs.inorgchem.0c01185.Epub 2020-07-18.

ヒトeIF3dとeIF3c、kとlのサブユニットを43Sと48Sのプレイニシエート複合体のアセンブリーに関与していることを示唆しています

Adapted formaldehyde gradient cross-linking protocol implicates human eIF3d and eIF3c, k and l subunits in the 43S and 48S pre-initiation complex assembly, respectively.
  • Anna Herrmannová
  • Terezie Prilepskaja
  • Susan Wagner
  • Darina Šikrová
  • Jakub Zeman
  • Kristýna Poncová
  • Leoš Shivaya Valášek
  • Nucleic Acids Res..2020 02;48(4):1969-1984. 5682903. doi: 10.1093/nar/gkz1185.

ドキソルビシンを用いた肝細胞癌に対するエピルビシンとシスプラチンの経皮注入と5-フルオロウラシルの全身注入の併用療法とソラフェニブの併用療法

Transarterial Infusion of Epirubicin and Cisplatin Combined With Systemic Infusion of 5-Flurouracil Versus Sorafenib for Hepatocellular Carcinoma With Refractoriness of Transarterial Chemoembolization Using Doxorubicin.
  • Sun Hong Yoo
  • Jung Hyun Kwon
  • Soon Woo Nam
  • Jong Yul Lee
  • Young Woon Kim
  • Dong Jae Shim
  • Sung Won Lee
  • Jeong Won Jang
  • Cancer Control.2020 Apr-Jun;27(2):1073274820935843. doi: 10.1177/1073274820935843.

第二世代抗精神病薬の副作用が統合失調症患者の機能に与える影響:世界的な横断的ウェブ調査

The impact on functioning of second-generation antipsychotic medication side effects for patients with schizophrenia: a worldwide, cross-sectional, web-based survey.
  • Rajiv Tandon
  • William R Lenderking
  • Catherine Weiss
  • Huda Shalhoub
  • Carla Dias Barbosa
  • Jun Chen
  • Mallik Greene
  • Stine R Meehan
  • Laëtitia Bouérat Duvold
  • Celso Arango
  • Ofer Agid
  • David Castle
  • Ann Gen Psychiatry.2020;19:42. 292. doi: 10.1186/s12991-020-00292-5.Epub 2020-07-13.

妊娠中の母親のインスリン抵抗性が新生児脂肪率に及ぼす影響の重要性

The importance of maternal insulin resistance throughout pregnancy on neonatal adiposity.
  • Rodrigo A Lima
  • Gernot Desoye
  • David Simmons
  • Roland Devlieger
  • Sander Galjaard
  • Rosa Corcoy
  • Juan M Adelantado
  • Fidelma Dunne
  • Jürgen Harreiter
  • Alexandra Kautzky-Willer
  • Peter Damm
  • Elisabeth R Mathiesen
  • Dorte M Jensen
  • Lise-Lotte T Andersen
  • Mette Tanvig
  • Annunziata Lapolla
  • Maria G Dalfra
  • Alessandra Bertolotto
  • Urszula Manta
  • Ewa Wender-Ozegowska
  • Agnieszka Zawiejska
  • David J Hill
  • Frank J Snoek
  • Judith G M Jelsma
  • Mireille van Poppel
  • Paediatr Perinat Epidemiol.2020 Apr;doi: 10.1111/ppe.12682.Epub 2020-04-30.

トコフェロールの水溶性を高めるための生体適合性超分子ホストとしてのヒアルロン酸ベースのβ-シクロデキストリングラフト共重合体

Hyaluronic-acid-based β-cyclodextrin grafted copolymers as biocompatible supramolecular hosts to enhance the water solubility of tocopherol.
  • Parbeen Singh
  • Li Wu
  • Xiaohong Ren
  • Wei Zhang
  • Yan Tang
  • Yongli Chen
  • Andrew Carrier
  • Xu Zhang
  • Jiwen Zhang
  • Int J Pharm.2020 Jun;586:119542. S0378-5173(20)30526-3. doi: 10.1016/j.ijpharm.2020.119542.Epub 2020-06-14.

バベシアビゲミナに自然感染した牛の酸化ストレス、微量元素、シアル酸、コリンエステラーゼ活性の状態

Status of oxidative stress, trace elements, sialic acid and cholinesterase activity in cattle naturally infected with Babesia bigemina.
  • Bijan Esmaeilnejad
  • Mousa Tavassoli
  • Bahram Dalir-Naghadeh
  • Awat Samiei
  • Sepideh Rajabi
  • Vahid Mohammadi
  • Ehsan Anassori
  • Shahin Ehteshamfar
  • Comp. Immunol. Microbiol. Infect. Dis..2020 May;71:101503. S0147-9571(20)30092-8. doi: 10.1016/j.cimid.2020.101503.Epub 2020-05-30.

PNPLA3-I148M変異体は、ヒト脂肪組織における多価不飽和トリグリセリドを増加させる

The PNPLA3-I148M variant increases polyunsaturated triglycerides in human adipose tissue.
  • Sami Qadri
  • Susanna Lallukka-Brück
  • Panu K Luukkonen
  • You Zhou
  • Amalia Gastaldelli
  • Marju Orho-Melander
  • Henna Sammalkorpi
  • Anne Juuti
  • Anne K Penttilä
  • Julia Perttilä
  • Antti Hakkarainen
  • Tiina E Lehtimäki
  • Matej Orešič
  • Tuulia Hyötyläinen
  • Leanne Hodson
  • Vesa M Olkkonen
  • Hannele Yki-Järvinen
  • Liver Int..2020 May;doi: 10.1111/liv.14507.Epub 2020-05-09.

重度の早期胎児成長制限を有する妊婦における母体のシルデナフィル対プラセボ。無作為化臨床試験

Maternal Sildenafil vs Placebo in Pregnant Women With Severe Early-Onset Fetal Growth Restriction: A Randomized Clinical Trial.
  • Anouk Pels
  • Jan Derks
  • Ayten Elvan-Taspinar
  • Joris van Drongelen
  • Marjon de Boer
  • Hans Duvekot
  • Judith van Laar
  • Jim van Eyck
  • Salwan Al-Nasiry
  • Marieke Sueters
  • Marinka Post
  • Wes Onland
  • Aleid van Wassenaer-Leemhuis
  • Christiana Naaktgeboren
  • Janus C Jakobsen
  • Christian Gluud
  • Ruben G Duijnhoven
  • Titia Lely
  • Sanne Gordijn
  • Wessel Ganzevoort
  • JAMA Netw Open.2020 Jun;3(6):e205323. 2767243. doi: 10.1001/jamanetworkopen.2020.5323.Epub 2020-06-01.

閉塞性睡眠時無呼吸症候群における硬性下顎骨再配置装置と半硬性下顎骨再配置装置の治療機序の違い.

Different therapeutic mechanisms of rigid and semi-rigid mandibular repositioning devices in obstructive sleep apnea syndrome.
  • Hokuto Suga
  • Katsuaki Mishima
  • Hiroyuki Nakano
  • Asuka Nakano
  • Mayumi Matsumura
  • Takamitsu Mano
  • Youichi Yamasaki
  • Yoshiya Ueyama
  • J Craniomaxillofac Surg.2014 Dec;42(8):1650-4. S1010-5182(14)00163-2. doi: 10.1016/j.jcms.2014.05.007.Epub 2014-05-20.

小児における食道pH-インピーダンスモニタリング:SIGENPワーキンググループによる適応、方法、解釈に関するポジションペーパー

Esophageal pH-impedance monitoring in children: position paper on indications, methodology and interpretation by the SIGENP working group.
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  • Giovanni Di Nardo
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ゼブラフィッシュのマクロファージの発生停止は、ミクログリアの枯渇の下で行われ、Csf1rに依存しない形質転換細胞が明らかになった

Zebrafish macrophage developmental arrest underlies depletion of microglia and reveals Csf1r-independent metaphocytes.
  • Laura E Kuil
  • Nynke Oosterhof
  • Giuliano Ferrero
  • Tereza Mikulášová
  • Martina Hason
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急性肝不全における肝移植-10年以上の振り返り

Liver Transplant in Acute Liver Failure - Looking Back Over 10 Years.
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  • Dinesh Balakrishnan
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KCCM 80179を用いて製造されたl-ヒスチジン一塩酸塩一水和物の全動物種に対する安全性と有効性

Safety and efficacy of l-histidine monohydrochloride monohydrate produced using KCCM 80179 for all animal species.
  • Vasileios Bampidis
  • Giovanna Azimonti
  • Maria de Lourdes Bastos
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  • Birgit Dusemund
  • Maryline Kouba
  • Mojca Kos Durjava
  • Marta López-Alonso
  • Secundino López Puente
  • Francesca Marcon
  • Baltasar Mayo
  • Alena Pechová
  • Mariana Petkova
  • Yolanda Sanz
  • Roberto Edoardo Villa
  • Ruud Woutersen
  • Lucio Costa
  • Francesco Cubadda
  • Noël Dierick
  • Gerhard Flachowsky
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若手バスケットボール選手の意図的な練習、機能的パフォーマンスと心理的特性.ベイズ型マルチレベル分析

Deliberate Practice, Functional Performance and Psychological Characteristics in Young Basketball Players: A Bayesian Multilevel Analysis.
  • Ahlan B Lima
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P/Q型カルシウムチャネルの新規スプライス部位変異と小児てんかんおよび遅発性進行性非エピソディック小脳運動失調との関連

Association of A Novel Splice Site Mutation in P/Q-Type Calcium Channels with Childhood Epilepsy and Late-Onset Slowly Progressive Non-Episodic Cerebellar Ataxia.
  • Claudia Stendel
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緑内障ドレナージ装置設置術およびその他の前房手術後の眼瞼下垂の増加率:プロスペクティブ解析

Increased rate of ptosis following glaucoma drainage device placement and other anterior segment surgery: a prospective analysis.
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  • Graefes Arch. Clin. Exp. Ophthalmol..2020 Jul;258(7):1533-1541. 10.1007/s00417-020-04630-x. doi: 10.1007/s00417-020-04630-x.Epub 2020-02-26.

インシリコ/インビトロスクリーニングとヒット評価により、新規のフェノチアジン系抗プリオン誘導体が同定された

In silico/in vitro screening and hit evaluation identified new phenothiazine anti-prion derivatives.
  • Ludovica Zaccagnini
  • Giulia Rossetti
  • Thanh Hoa Tran
  • Giulia Salzano
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  • Eur J Med Chem.2020 Jun;196:112295. S0223-5234(20)30264-6. doi: 10.1016/j.ejmech.2020.112295.Epub 2020-04-08.

サンパウロ州リベイラオプレト大学病院における糖尿病患者における非糖尿病性腎疾患の有病率

The Prevalence of Nondiabetic Renal Diseases in Patients with Diabetes Mellitus in the University Hospital of Ribeirão Preto, São Paulo.
  • Diego Agra Souza
  • Gyl Eanes Barros Silva
  • Igor Lima Fernandes
  • Dyego José Araújo de Brito
  • Monique Pereira Rêgo Muniz
  • Osvaldo Merege Vieira Neto
  • Roberto Silva Costa
  • Márcio Dantas
  • Miguel Moyses Neto
  • J Diabetes Res.2020;2020:2129459. doi: 10.1155/2020/2129459.Epub 2020-06-13.

高度な酸化生物活性炭プロセスとFe/ヒュームス還元菌を組み合わせた逆浸透濃縮物からの有機物の除去

Removing organic matters from reverse osmosis concentrate using advanced oxidation-biological activated carbon process combined with Fe/humus-reducing bacteria.
  • Xiaoyan Wang
  • Jiaohui Xia
  • Shaoxuan Ding
  • Shuo Zhang
  • Menghong Li
  • Zhenxiao Shang
  • Jie Lu
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  • Ecotoxicol. Environ. Saf..2020 Jul;203:110945. S0147-6513(20)30784-3. doi: 10.1016/j.ecoenv.2020.110945.Epub 2020-07-15.

新生子豚の母体の鉄の状態と肝鉄貯蔵量にスクロソミアル第二鉄ピロリン酸塩と健康な妊娠中の雌豚の経口サプリメントの効果

Effect of Oral Supplementation of Healthy Pregnant Sows with Sucrosomial Ferric Pyrophosphate on Maternal Iron Status and Hepatic Iron Stores in Newborn Piglets.
  • Rafał Mazgaj
  • Mateusz Szudzik
  • Paweł Lipiński
  • Aneta Jończy
  • Ewa Smuda
  • Marian Kamyczek
  • Beata Cieślak
  • Dorine Swinkels
  • Małgorzata Lenartowicz
  • Rafał R Starzyński
  • Animals (Basel).2020 Jun;10(7). E1113. doi: 10.3390/ani10071113.Epub 2020-06-29.

PCSK9は敗血症性ショック患者の死亡率と関連している:ALBIOS試験のデータ

PCSK9 is associated with mortality in patients with septic shock: data from the ALBIOS study.
  • Alessandra Vecchié
  • Aldo Bonaventura
  • Jennifer Meessen
  • Deborah Novelli
  • Silvia Minetti
  • Edoardo Elia
  • Daniele Ferrara
  • Anna Maria Ansaldo
  • Vittorio Scaravilli
  • Silvia Villa
  • Luca Ferla
  • Pietro Caironi
  • Roberto Latini
  • Federico Carbone
  • Fabrizio Montecucco
  • J. Intern. Med..2020 Jul;doi: 10.1111/joim.13150.Epub 2020-07-19.

大うつ病または双極性障害を有する成人患者における静注ケタミンの安全性と忍容性:カナダのラピッド・トリートメント・センター・オブ・エクセレンスの結果

Safety and tolerability of IV ketamine in adults with major depressive or bipolar disorder: results from the Canadian rapid treatment center of excellence.
  • Nelson B Rodrigues
  • Roger S McIntyre
  • Orly Lipsitz
  • Yena Lee
  • Danielle S Cha
  • Flora Nasri
  • Hartej Gill
  • Leanna M W Lui
  • Mehala Subramaniapillai
  • Kevin Kratiuk
  • Kangguang Lin
  • Roger Ho
  • Rodrigo B Mansur
  • Joshua D Rosenblat
  • Expert Opin Drug Saf.2020 Jun;:1-10. doi: 10.1080/14740338.2020.1776699.Epub 2020-06-15.

結核菌や大腸菌のニコチンアミダーゼ・ピラジナミダーゼ活性にはメタロシャペロンが必要である

Metallochaperones Are Needed for Mycobacterium tuberculosis and Escherichia coli Nicotinamidase-Pyrazinamidase Activity.
  • Patricia Sheen
  • Anuntxi Monsalve
  • Jhanina Campos
  • Rodolfo Huerta
  • Ricardo Antiparra
  • Héctor Arteaga
  • Patricia Duran
  • Carlos Bueno
  • Daniela E Kirwan
  • Robert H Gilman
  • Mirko Zimic
  • J. Bacteriol..2020 Jan;202(2). e00331-19. doi: 10.1128/JB.00331-19.Epub 2020-01-02.

長引く紛争における保健医療従事者の教育・訓練提供の課題:シリア北西部の非政府支配地域に焦点を当てて

Challenges of providing healthcare worker education and training in protracted conflict: a focus on non-government controlled areas in north west Syria.
  • Yamama Bdaiwi
  • Diana Rayes
  • Ammar Sabouni
  • Lina Murad
  • Fouad Fouad
  • Waseem Zakaria
  • Mahmoud Hariri
  • Abdelkarim Ekzayez
  • Ahmad Tarakji
  • Aula Abbara
  • Confl Health.2020;14:42. 287. doi: 10.1186/s13031-020-00287-9.Epub 2020-07-08.

インターロイキン-18と細胞障害は、独立した相乗的な原因であり、マウスウイルス誘発性高炎症の原因である

Interleukin-18 and cytotoxic impairment are independent and synergistic causes of murine virus-induced hyperinflammation.
  • Paul Tsoukas
  • Emily Rapp
  • Lauren Van Der Kraak
  • Eric S Weiss
  • Vinh Dang
  • Corinne Schneider
  • Edwin Klein
  • Jennifer Picarsic
  • Rosalba Salcedo
  • Charles Andrew Stewart
  • Scott Canna
  • Blood.2020 Jun;blood.2019003846. doi: 10.1182/blood.2019003846.Epub 2020-06-26.

vivax マラリア原虫患者におけるタフェノキンの有効性の薬理遺伝学的評価

Pharmacogenetic assessment of tafenoquine efficacy in patients with Plasmodium vivax malaria.
  • Pamela L St Jean
  • Gavin C K W Koh
  • John J Breton
  • Fe E J Espino
  • Tran T Hien
  • Srivicha Krudsood
  • Marcus V G Lacerda
  • Alejandro Llanos-Cuentas
  • Chanthap Lon
  • Rezika Mohammed
  • Chayadol S Namaik-Larp
  • Dhelio B Pereira
  • David L Saunders
  • Ivan D Velez
  • Daniel Yilma
  • Maria F Villegas
  • Stephan Duparc
  • Justin A Green
  • Pharmacogenet. Genomics.2020 Jun;doi: 10.1097/FPC.0000000000000407.Epub 2020-06-16.

カーディオリピンは、細菌のトランスロコンの安定性と最適な膜タンパク質のトランスロケーションと挿入のために、生体内で必要とされています

Cardiolipin is required in vivo for the stability of bacterial translocon and optimal membrane protein translocation and insertion.
  • Sergey Ryabichko
  • Vilena de Melo Ferreira
  • Heidi Vitrac
  • Ramziya Kiyamova
  • William Dowhan
  • Mikhail Bogdanov
  • Sci Rep.2020 Apr;10(1):6296. 10.1038/s41598-020-63280-5. doi: 10.1038/s41598-020-63280-5.Epub 2020-04-14.

西洋のハウスマウスの近東起源とヨーロッパへの飛散を追う

Tracking the Near Eastern origins and European dispersal of the western house mouse.
  • Thomas Cucchi
  • Katerina Papayianni
  • Sophie Cersoy
  • Laetitia Aznar-Cormano
  • Antoine Zazzo
  • Régis Debruyne
  • Rémi Berthon
  • Adrian Bălășescu
  • Alan Simmons
  • François Valla
  • Yannis Hamilakis
  • Fanis Mavridis
  • Marjan Mashkour
  • Jamshid Darvish
  • Roohollah Siahsarvi
  • Fereidoun Biglari
  • Cameron A Petrie
  • Lloyd Weeks
  • Alireza Sardari
  • Sepideh Maziar
  • Christiane Denys
  • David Orton
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  • Jeremy B Searle
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  • François Bonhomme
  • Jean-Christophe Auffray
  • Jean-Denis Vigne
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ミスマッチ修復不全癌に対するフレームシフトペプチドネオアンチゲンベースのワクチン。A Phase I/IIa 臨床試験を実施しました

A Frameshift Peptide Neoantigen-Based Vaccine for Mismatch Repair-Deficient Cancers: A Phase I/IIa Clinical Trial.
  • Matthias Kloor
  • Miriam Reuschenbach
  • Claudia Pauligk
  • Julia Karbach
  • Mohammad-Reza Rafiyan
  • Salah-Eddin Al-Batran
  • Mirjam Tariverdian
  • Elke Jäger
  • Magnus von Knebel Doeberitz
  • Clin. Cancer Res..2020 Jun;1078-0432.CCR-19-3517. doi: 10.1158/1078-0432.CCR-19-3517.Epub 2020-06-15.

HER2 陽性乳癌患者 6,122 例を対象とした集団ベースの研究におけるトリプル陽性と予後パラメータおよび全生存期間との関連性:研究データベースに基づく実際の臨床実践の分析

Association of triple positivity with prognostic parameters and overall survival in a population-based study of 6,122 HER2-positive breast cancer patients: analysis of real-world clinical practice based on a research database.
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  • J Prausova
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  • Neoplasma.2020 Jul;191023N1080. doi: 10.4149/neo_2020_191023N1080.Epub 2020-07-02.

ミトコンドリア障害は、マウスの部分的または完全なジストロフィン喪失の初期の結果である

Mitochondrial Dysfunction Is an Early Consequence of Partial or Complete Dystrophin Loss in Mice.
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  • Aidan Yackly
  • Sushil K Mahata
  • Jonathan Wanagat
  • Linsey Stiles
  • Lorraine P Turcotte
  • Rachelle H Crosbie
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  • Front Physiol.2020;11:690. doi: 10.3389/fphys.2020.00690.Epub 2020-06-19.

東・南部アフリカにおける性と生殖のための健康商品へのアクセス:ケニア、タンザニア、ウガンダ、ザンビアにおける入手可能性、手頃な価格、在庫切れについてのクロスカントリー比較

Access to sexual and reproductive health commodities in East and Southern Africa: a cross-country comparison of availability, affordability and stock-outs in Kenya, Tanzania, Uganda and Zambia.
  • Gaby I Ooms
  • Denis Kibira
  • Tim Reed
  • Hendrika A van den Ham
  • Aukje K Mantel-Teeuwisse
  • Gemma Buckland-Merrett
  • BMC Public Health.2020 Jul;20(1):1053. 10.1186/s12889-020-09155-w. doi: 10.1186/s12889-020-09155-w.Epub 2020-07-03.