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日本語AIでPubMedを検索

日本語AIでPubMedを検索

PubMedの提供する医学論文データベースを日本語で検索できます。AI(Deep Learning)を活用した機械翻訳エンジンにより、精度高く日本語へ翻訳された論文をご参照いただけます。

みんなが読んでいる論文

小児歯科医院関連のMycobacterium abscessus感染症アウトブレイク

Pediatric Dental Clinic-Associated Outbreak of Mycobacterium abscessus Infection.
  • Lindsay A Hatzenbuehler
  • Melissa Tobin-D'Angelo
  • Cherie Drenzek
  • Gianna Peralta
  • Lisa C Cranmer
  • Evan J Anderson
  • Sarah S Milla
  • Shelly Abramowicz
  • Jumi Yi
  • Joseph Hilinski
  • Roy Rajan
  • Matthew K Whitley
  • Verlia Gower
  • Frank Berkowitz
  • Craig A Shapiro
  • Joseph K Williams
  • Paula Harmon
  • Andi L Shane
  • J Pediatric Infect Dis Soc.2017 Sep;6(3):e116-e122. 4100290. doi: 10.1093/jpids/pix065.

LKB1の不活性化は、サバイビンのp53依存的なアップレギュレーションを介してセントロメア欠損とゲノム不安定性をもたらす

LKB1 inactivation leads to centromere defects and genome instability via p53-dependent upregulation of survivin.
  • Li-Yan Jin
  • Kui Zhao
  • Long-Jiang Xu
  • Rui-Xun Zhao
  • Kaitlin D Werle
  • Yong Wang
  • Xiao-Long Liu
  • Qiu Chen
  • Zhuo-Jun Wu
  • Ke Zhang
  • Ying Zhao
  • Guo-Qin Jiang
  • Feng-Mei Cui
  • Zhi-Xiang Xu
  • Aging (Albany NY).2020 Jul;12. 103473. doi: 10.18632/aging.103473.Epub 2020-07-15.

臨床的に孤立した多発性硬化症症候群を対象としたミノサイクリンの臨床試験

Trial of Minocycline in a Clinically Isolated Syndrome of Multiple Sclerosis.
  • Luanne M Metz
  • David K B Li
  • Anthony L Traboulsee
  • Pierre Duquette
  • Misha Eliasziw
  • Graziela Cerchiaro
  • Jamie Greenfield
  • Andrew Riddehough
  • Michael Yeung
  • Marcelo Kremenchutzky
  • Galina Vorobeychik
  • Mark S Freedman
  • Virender Bhan
  • Gregg Blevins
  • James J Marriott
  • Francois Grand'Maison
  • Liesly Lee
  • Manon Thibault
  • Michael D Hill
  • V Wee Yong
  • N. Engl. J. Med..2017 06;376(22):2122-2133. doi: 10.1056/NEJMoa1608889.

扁桃リトラクターによる舌水腫は、超音波検査で検出された扁桃摘出手術を受けた小児患者の新たな合併症となりうるか?A Prospective, Case-Controlled, Observational Study

Can Tonsillar Retractor-Induced Tongue Edema Be a New Complication in Pediatric Patients Undergoing Tonsillectomy Detected by Ultrasonography? A Prospective, Case-Controlled, Observational Study.
  • Merih Onal
  • Bahar Colpan
  • Cagdas Elsurer
  • Mete Kaan Bozkurt
  • Mehmet Ozturk
  • Ozkan Onal
  • Alparslan Turan
  • Ear Nose Throat J.2020 Jul;:145561320934918. doi: 10.1177/0145561320934918.Epub 2020-07-07.

分子ドッキングベースの仮想スクリーニングと分子動力学シミュレーションによる新規タンキラーゼ阻害剤の発見

Discovery of Novel Tankyrase Inhibitors through Molecular Docking-Based Virtual Screening and Molecular Dynamics Simulation Studies.
  • Vladimir P Berishvili
  • Alexander N Kuimov
  • Andrew E Voronkov
  • Eugene V Radchenko
  • Pradeep Kumar
  • Yahya E Choonara
  • Viness Pillay
  • Ahmed Kamal
  • Vladimir A Palyulin
  • Molecules.2020 Jul;25(14). E3171. doi: 10.3390/molecules25143171.Epub 2020-07-11.

神経細胞カルシウムセンサータンパク質のミリストイル化形態の細菌発現と精製への新規アプローチ

A Novel Approach to Bacterial Expression and Purification of Myristoylated Forms of Neuronal Calcium Sensor Proteins.
  • Vasiliy I Vladimirov
  • Viktoriia E Baksheeva
  • Irina V Mikhailova
  • Ramis G Ismailov
  • Ekaterina A Litus
  • Natalia K Tikhomirova
  • Aliya A Nazipova
  • Sergei E Permyakov
  • Evgeni Yu Zernii
  • Dmitry V Zinchenko
  • Biomolecules.2020 Jul;10(7). E1025. doi: 10.3390/biom10071025.Epub 2020-07-10.

収縮期血圧が上昇した急性期虚血性脳卒中患者における尿酸と予後の関連に及ぼす腎機能の影響

Effect of renal function on association between uric acid and prognosis in acute ischemic stroke patients with elevated systolic blood pressure.
  • Xiaowei Zheng
  • Aili Wang
  • Zhengbao Zhu
  • Yanbo Peng
  • Hao Peng
  • Chongke Zhong
  • Xiaoqing Bu
  • Daoxia Guo
  • Tan Xu
  • Jing Chen
  • Tian Xu
  • Zhong Ju
  • Deqin Geng
  • Yonghong Zhang
  • Jiang He
  • Neurol. Res..2020 Jul;:1-7. doi: 10.1080/01616412.2020.1792688.Epub 2020-07-13.

ホモロジーモデリング、ドッキング、分子動力学シミュレーションによるSPAKのC末端ドメインの構造予測とRFXV/Iモチーフへの結合の解析を行った

Structure prediction of SPAK C-terminal domain and analysis of its binding to RFXV/I motifs by homology modelling, docking, and molecular dynamics simulation studies.
  • Mubarak A Alamri
  • Ahmed D Alafnan
  • Obaid Afzal
  • Alhumaidi B Alabbas
  • Safar M Alqahtani
  • Curr Comput Aided Drug Des.2020 Jul;CAD-EPUB-108091. doi: 10.2174/1573409916666200712140941.Epub 2020-07-12.

AQP4-IgG血清陽性の視神経脊髄炎スペクトラム障害における眼窩の変化

Altered fovea in AQP4-IgG-seropositive neuromyelitis optica spectrum disorders.
  • Seyedamirhosein Motamedi
  • Frederike C Oertel
  • Sunil K Yadav
  • Ella M Kadas
  • Margit Weise
  • Joachim Havla
  • Marius Ringelstein
  • Orhan Aktas
  • Philipp Albrecht
  • Klemens Ruprecht
  • Judith Bellmann-Strobl
  • Hanna G Zimmermann
  • Friedemann Paul
  • Alexander U Brandt
  • Neurol Neuroimmunol Neuroinflamm.2020 Sep;7(5). e805. doi: 10.1212/NXI.0000000000000805.Epub 2020-06-23.

小児フィラデルフィア染色体陽性白血病におけるポナチニブ:小児慢性骨髄性白血病の国際レジストリ研究

Ponatinib in childhood Philadelphia chromosome-positive leukaemias: an international registry of childhood chronic myeloid leukaemia study.
  • Frédéric Millot
  • Meinolf Suttorp
  • Anne B Versluys
  • Krzysztof Kalwak
  • Brigitte Nelken
  • Stephane Ducassou
  • Yves Bertrand
  • André Baruchel
  • Eur. J. Cancer.2020 Jul;136:107-112. S0959-8049(20)30287-2. doi: 10.1016/j.ejca.2020.05.020.Epub 2020-07-12.

バイアビリティPCRは、非眼球表面がトラコーマにおけるクラミジア・トラコマチス感染の伝播に寄与する可能性を示している

Viability PCR shows that non-ocular surfaces could contribute to transmission of Chlamydia trachomatis infection in trachoma.
  • Bart Versteeg
  • Hristina Vasileva
  • Joanna Houghton
  • Anna Last
  • Oumer Shafi Abdurahman
  • Virginia Sarah
  • David Macleod
  • Anthony W Solomon
  • Martin J Holland
  • Nicholas Thomson
  • Matthew J Burton
  • PLoS Negl Trop Dis.2020 Jul;14(7):e0008449. PNTD-D-20-00590. doi: 10.1371/journal.pntd.0008449.Epub 2020-07-15.

ABL1チロシンキナーゼの阻害は、HTLV-1関連筋症/熱帯性痙性パラパレシス患者の末梢血単核細胞におけるHTLV-1プロウイルス負荷を減少させる

Inhibition of ABL1 tyrosine kinase reduces HTLV-1 proviral loads in peripheral blood mononuclear cells from patients with HTLV-1-associated myelopathy/tropical spastic paraparesis.
  • Daisuke Kodama
  • Masakazu Tanaka
  • Toshio Matsuzaki
  • Kimiko Izumo
  • Nobuaki Nakano
  • Eiji Matsuura
  • Mineki Saito
  • Masahiro Nagai
  • Masahisa Horiuchi
  • Atae Utsunomiya
  • Hiroshi Takashima
  • Ryuji Kubota
  • Shuji Izumo
  • PLoS Negl Trop Dis.2020 Jul;14(7):e0008361. PNTD-D-19-01297. doi: 10.1371/journal.pntd.0008361.Epub 2020-07-15.

植物のアルビニズム:クロロフィルの損失をはるかに超えて。野生型とアルビノのロイヤルポインシアナ(Delonix regia)の苗の構造と生理学的側面

Albinism in plants: far beyond the loss of chlorophyll. Structural and physiological aspects of wild-type and albino royal poinciana (Delonix regia) seedlings.
  • Lázara Aline Simões Silva
  • Vitor Fernandes Sampaio
  • Lília Cristina Souza Barbosa
  • Mariana Machado
  • Denisele Neuza Aline Flores-Borges
  • Juliana de Fátima Sales
  • Denis Coelho de Oliveira
  • Juliana Lischka Sampaio Mayer
  • Vinicius Coelho Kuster
  • Diego Ismael Rocha
  • Plant Biol (Stuttg).2020 Jun;doi: 10.1111/plb.13146.Epub 2020-06-16.

gen.nov. sp.nov.は、地衣類の最初のバクテリオクロロフィルを含有し、精神親和性および酸性親和性のバクテリオビオンである

gen. nov., sp. nov., the first bacteriochlorophyll -containing, psychrophilic and acidophilic bacteriobiont of lichen species.
  • Timofey A Pankratov
  • Denis S Grouzdev
  • Ekaterina O Patutina
  • Tatiana V Kolganova
  • Julia J Berestovskaya
  • Aleksandr A Ashikhmin
  • Int. J. Syst. Evol. Microbiol..2020 Jul;doi: 10.1099/ijsem.0.004318.Epub 2020-07-13.

液体マイクロジャンクション表面サンプリング-質量分析法を用いた迅速で包括的なリピドミクス分析のためのTiO2コーティング上のグリセロリン脂質からの糖脂質/スフィンゴ脂質の分離

Separation of Glycolipids/Sphingolipids from Glycerophospholipids on TiO2 Coating in Aprotic Solvent for Rapid Comprehensive Lipidomic Analysis with Liquid Microjunction Surface Sampling-Mass Spectrometry.
  • Zehui Huang
  • Qian Wu
  • Hongmei Lu
  • Yang Wang
  • Zhimin Zhang
  • Anal. Chem..2020 Jul;doi: 10.1021/acs.analchem.0c01870.Epub 2020-07-15.

患者由来の細胞アトラスが神経膠芽腫の精密標的化に役立つ

A Patient-Derived Cell Atlas Informs Precision Targeting of Glioblastoma.
  • Patrik Johansson
  • Cecilia Krona
  • Soumi Kundu
  • Milena Doroszko
  • Sathishkumar Baskaran
  • Linnéa Schmidt
  • Claire Vinel
  • Elin Almstedt
  • Ramy Elgendy
  • Ludmila Elfineh
  • Caroline Gallant
  • Sara Lundsten
  • Fernando J Ferrer Gago
  • Aleksi Hakkarainen
  • Petra Sipilä
  • Maria Häggblad
  • Ulf Martens
  • Bo Lundgren
  • Melanie M Frigault
  • David P Lane
  • Fredrik J Swartling
  • Lene Uhrbom
  • Marika Nestor
  • Silvia Marino
  • Sven Nelander
  • Cell Rep.2020 Jul;32(2):107897. S2211-1247(20)30878-0. doi: 10.1016/j.celrep.2020.107897.

ヒドロキシクロロキンによるCOVID-19から最前線の医療従事者を守るための事前暴露予防法。カナダ、トロントで行われた無作為化プラセボ対照多施設試験のプロトコールの構造化された要約

Protecting Frontline Health Care Workers from COVID-19 with Hydroxychloroquine Pre-exposure Prophylaxis: A structured summary of a study protocol for a randomised placebo-controlled multisite trial in Toronto, Canada.
  • Julie K Wright
  • Darrell H S Tan
  • Sharon L Walmsley
  • Jennifer Hulme
  • Erin O'Connor
  • Carolyn Snider
  • Ivy Cheng
  • Adrienne K Chan
  • Bjug Borgundvaag
  • Shelley McLeod
  • Michael H Gollob
  • Rosemarie J Clarke
  • Linda Dresser
  • Fatima Haji
  • Tony Mazzulli
  • Samira Mubareka
  • Peter Jüni
  • Dominic Lee
  • George Tomlinson
  • Kevin C Kain
  • Megan Landes
  • Trials.2020 Jul;21(1):647. 10.1186/s13063-020-04577-8. doi: 10.1186/s13063-020-04577-8.Epub 2020-07-14.

高脂肪食と抗生物質が協調的にミトコンドリアのバイオエネルギーを損なうことで、炎症性腸疾患の前段階を悪化させているバイオシスを誘発する

High-Fat Diet and Antibiotics Cooperatively Impair Mitochondrial Bioenergetics to Trigger Dysbiosis that Exacerbates Pre-inflammatory Bowel Disease.
  • Jee-Yon Lee
  • Stephanie A Cevallos
  • Mariana X Byndloss
  • Connor R Tiffany
  • Erin E Olsan
  • Brian P Butler
  • Briana M Young
  • Andrew W L Rogers
  • Henry Nguyen
  • Kyongchol Kim
  • Sang-Woon Choi
  • Eunsoo Bae
  • Je Hee Lee
  • Ui-Gi Min
  • Duk-Chul Lee
  • Andreas J Bäumler
  • Cell Host Microbe.2020 Jul;S1931-3128(20)30303-6. doi: 10.1016/j.chom.2020.06.001.Epub 2020-07-09.

トロンボスポンジン-1は、心臓内皮細胞の感染初期段階におけるYes-Associated Proteinの核内転座に重要な役割を果たしている

Thrombospondin-1 Plays an Essential Role in Yes-Associated Protein Nuclear Translocation during the Early Phase of Infection in Heart Endothelial Cells.
  • Ashutosh Arun
  • Kayla J Rayford
  • Ayorinde Cooley
  • Girish Rachakonda
  • Fernando Villalta
  • Siddharth Pratap
  • Maria F Lima
  • Nader Sheibani
  • Pius N Nde
  • Int J Mol Sci.2020 Jul;21(14). E4912. doi: 10.3390/ijms21144912.Epub 2020-07-12.

腸内マイクロバイオームは、胆汁酸-タイプI-IFNシグナル伝達軸を介してアルファウイルスの感染と伝播を制限する

The Intestinal Microbiome Restricts Alphavirus Infection and Dissemination through a Bile Acid-Type I IFN Signaling Axis.
  • Emma S Winkler
  • Swathi Shrihari
  • Barry L Hykes
  • Scott A Handley
  • Prabhakar S Andhey
  • Yan-Jang S Huang
  • Amanda Swain
  • Lindsay Droit
  • Kranthi K Chebrolu
  • Matthias Mack
  • Dana L Vanlandingham
  • Larissa B Thackray
  • Marina Cella
  • Marco Colonna
  • Maxim N Artyomov
  • Thaddeus S Stappenbeck
  • Michael S Diamond
  • Cell.2020 Jul;S0092-8674(20)30806-0. doi: 10.1016/j.cell.2020.06.029.Epub 2020-07-08.

妊娠後期の熱ストレスは、豚モデルでは、変更された子孫の腸内微生物のコロニゼーションと血清代謝物と母体の微生物伝達を混乱させる

Heat stress during late gestation disrupts maternal microbial transmission with altered offspring's gut microbial colonization and serum metabolites in a pig model.
  • Jianwen He
  • Weijiang Zheng
  • Chengyuan Tao
  • Huiduo Guo
  • Yongqiang Xue
  • Ruqian Zhao
  • Wen Yao
  • Environ. Pollut..2020 Jun;266(Pt 3):115111. S0269-7491(20)31749-8. doi: 10.1016/j.envpol.2020.115111.Epub 2020-06-29.

オクラホマ州南東部に生息するツバメHirundo rustica (Aves: Passeriformes: Hirundinidae)からの新種Eimerian (Apicomplexa: Eimeriidae)。新世界のPasseriformesから第4のEimerian種

A New Eimerian (Apicomplexa: Eimeriidae) from the Barn Swallow, Hirundo rustica (Aves: Passeriformes: Hirundinidae), in Southeastern Oklahoma: The Fourth Eimerian Species from New World Passeriformes.
  • Chris T McAllister
  • John A Hnida
  • J. Parasitol..2019 Oct;105(5):693-696. 420579. doi: 10.1645/19-105.