あなたは歯科・医療関係者ですか?

WHITE CROSSは、歯科・医療現場で働く方を対象に、良質な歯科医療情報の提供を目的とした会員制サイトです。

日本語AIでPubMedを検索

日本語AIでPubMedを検索

PubMedの提供する医学論文データベースを日本語で検索できます。AI(Deep Learning)を活用した機械翻訳エンジンにより、精度高く日本語へ翻訳された論文をご参照いただけます。

みんなが読んでいる論文

ニコチンアミドホスホリボシルトランスフェラーゼ(Nampt)/ニコチンアミドアデニンジヌクレオチド(NAD)軸は、カルシウムハンドリング経路を調節することで心房細動を抑制する

Nicotinamide Phosphoribosyltransferase (Nampt)/Nicotinamide Adenine Dinucleotide (NAD) Axis Suppresses Atrial Fibrillation by Modulating the Calcium Handling Pathway.
  • Duo Feng
  • DongZhu Xu
  • Nobuyuki Murakoshi
  • Kazuko Tajiri
  • Rujie Qin
  • Saori Yonebayashi
  • Yuta Okabe
  • Siqi Li
  • Zixun Yuan
  • Kazutaka Aonuma
  • Masaki Ieda
  • Int J Mol Sci.2020 Jun;21(13). E4655. doi: 10.3390/ijms21134655.Epub 2020-06-30.

t-PA遺伝子のDNAメチル化は、電気けいれん療法を受けているうつ病患者から分離された様々な免疫細胞サブタイプの間で異なる

DNA Methylation of the t-PA Gene Differs Between Various Immune Cell Subtypes Isolated From Depressed Patients Receiving Electroconvulsive Therapy.
  • Nicole Moschny
  • Kirsten Jahn
  • Malek Bajbouj
  • Hannah Benedictine Maier
  • Matthias Ballmaier
  • Abdul Qayyum Khan
  • Christoph Pollak
  • Stefan Bleich
  • Helge Frieling
  • Alexandra Neyazi
  • Front Psychiatry.2020;11:571. doi: 10.3389/fpsyt.2020.00571.Epub 2020-06-19.

サイトメガロウイルス血清陽性と多発性硬化症の関連における地域差。システマティックレビューおよびメタアナリシス

Regional differences in the association of cytomegalovirus seropositivity and multiple sclerosis: A systematic review and meta-analysis.
  • Smathorn Thakolwiboon
  • Hannah Zhao-Fleming
  • Amputch Karukote
  • Pavida Pachariyanon
  • Hayley Gibler Williams
  • Mirla Avila
  • Mult Scler Relat Disord.2020 Jul;45:102393. S2211-0348(20)30468-5. doi: 10.1016/j.msard.2020.102393.Epub 2020-07-12.

リチウムイオン電池のための有望な負極材料としての2-カルボキシエチルゲルマニウムセスキオキシド

2-Carboxyethylgermanium Sesquioxide as A Promising Anode Material for Li-Ion Batteries.
  • Evgeniya A Saverina
  • Roman R Kapaev
  • Pavel V Stishenko
  • Alexey S Galushko
  • Victoriya A Balycheva
  • Valentine P Ananikov
  • Mikhail P Egorov
  • Viatcheslav V Jouikov
  • Pavel A Troshin
  • Mikhail A Syroeshkin
  • ChemSusChem.2020 Jun;13(12):3137-3146. doi: 10.1002/cssc.202000852.Epub 2020-05-26.

2種類以上の降圧薬を服用している無制御高血圧症患者を対象に、降圧薬の自己管理、血圧の自己測定、低カロリー・低ナトリウム食、身体運動からなる多因子介入の有効性。MEDICHY試験

Effectiveness of a multifactorial intervention, consisting of self-management of antihypertensive medication, self-measurement of blood pressure, hypocaloric and low sodium diet, and physical exercise, in patients with uncontrolled hypertension taking 2 or more antihypertensive drugs: The MEDICHY study.
  • Fabián Unda Villafuerte
  • Joan Llobera Cànaves
  • Patricia Lorente Montalvo
  • María Lucía Moreno Sancho
  • Bartolomé Oliver Oliver
  • Patricia Bassante Flores
  • Andreu Estela Mantolan
  • Joan Pou Bordoy
  • Tomás Rodríguez Ruiz
  • Ana Requena Hernández
  • Alfonso Leiva
  • Matíes Torrent Quetglas
  • José María Coll Benejam
  • Pilar D'Agosto Forteza
  • Fernando Rigo Carratalà
  • Medicine (Baltimore).2020 Apr;99(17):e19769. 00005792-202004240-00028. doi: 10.1097/MD.0000000000019769.

選択的LXRアゴニストDMHCAは、2型糖尿病における網膜および骨髄の機能障害を修正する

Selective LXR agonist DMHCA corrects retinal and bone marrow dysfunction in type 2 diabetes.
  • Cristiano P Vieira
  • Seth D Fortmann
  • Masroor Hossain
  • Ana Leda Longhini
  • Sandra S Hammer
  • Bright Asare-Bediako
  • David K Crossman
  • Micheli S Sielski
  • Yvonne Adu-Agyeiwaah
  • Mariana Dupont
  • Jason L Floyd
  • Sergio Li Calzi
  • Todd Lydic
  • Robert S Welner
  • Gary J Blanchard
  • Julia V Busik
  • Maria B Grant
  • JCI Insight.2020 Jul;5(13). 137230. doi: 10.1172/jci.insight.137230.Epub 2020-07-09.

BPin前駆体のCuフッ素化による高モル活性F6-フルオロ-L-DOPAの合成(英文

Synthesis of high-molar-activity [F]6-fluoro-L-DOPA suitable for human use via Cu-mediated fluorination of a BPin precursor.
  • Andrew V Mossine
  • Sean S Tanzey
  • Allen F Brooks
  • Katarina J Makaravage
  • Naoko Ichiishi
  • Jason M Miller
  • Bradford D Henderson
  • Thomas Erhard
  • Christian Bruetting
  • Marc B Skaddan
  • Melanie S Sanford
  • Peter J H Scott
  • Nat Protoc.2020 05;15(5):1742-1759. 10.1038/s41596-020-0305-9. doi: 10.1038/s41596-020-0305-9.Epub 2020-04-08.

ジクロフェナクナトリウム関節内ゼラチン微小球製剤開発のための品質リスクマネジメントと品質バイデザイン

Quality Risk Management and Quality by Design for the Development of Diclofenac Sodium Intra-articular Gelatin Microspheres.
  • Alexandros Nakas
  • Athanasia M Dalatsi
  • Afroditi Kapourani
  • Konstantinos N Kontogiannopoulos
  • Andreana N Assimopoulou
  • Panagiotis Barmpalexis
  • AAPS PharmSciTech.2020 May;21(4):127. 10.1208/s12249-020-01678-0. doi: 10.1208/s12249-020-01678-0.Epub 2020-05-10.

2 段階の MACE プロセスにおける金属触媒の形状とエッチング液の組成を制御したシリコンナノワイヤの微細構造の工学。成長メカニズムの詳細な解析

Engineering the Microstructure of Silicon Nanowires by Controlling the Shape of the Metal Catalyst and Composition of the Etchant in a Two-step MACE Process: An In-depth Analysis of the Growth Mechanism.
  • T K Adhila
  • Hemaprabha Elangovan
  • Siju John
  • Kamanio Chattopdhyay
  • Harish Chandra Barshilia
  • Langmuir.2020 Jul;doi: 10.1021/acs.langmuir.0c01164.Epub 2020-07-20.

FGF19シグナル伝達活性化Srcによる肝ファルネソイドX受容体のリン酸化は、コレステロール値を維持し、動脈硬化から保護する

Phosphorylation of hepatic farnesoid X receptor by FGF19 signaling-activated Src maintains cholesterol levels and protects from atherosclerosis.
  • Sangwon Byun
  • Hyunkyung Jung
  • Jinjing Chen
  • Young-Chae Kim
  • Dong-Hyun Kim
  • Bo Kong
  • Grace Guo
  • Byron Kemper
  • Jongsook Kim Kemper
  • J. Biol. Chem..2019 05;294(22):8732-8744. RA119.008360. doi: 10.1074/jbc.RA119.008360.Epub 2019-04-17.

培養におけるヒト大腸組織の分化。カルシウムが経上皮電気抵抗および組織凝集特性に及ぼす影響

Differentiation of human colon tissue in culture: Effects of calcium on trans-epithelial electrical resistance and tissue cohesive properties.
  • Shannon D McClintock
  • Durga Attili
  • Michael K Dame
  • Aliah Richter
  • Sabrina S Silvestri
  • Maliha M Berner
  • Margaret S Bohm
  • Kateryna Karpoff
  • Caroline L McCarthy
  • Jason R Spence
  • James Varani
  • Muhammad N Aslam
  • PLoS ONE.2020;15(3):e0222058. PONE-D-19-23237. doi: 10.1371/journal.pone.0222058.Epub 2020-03-05.

microRNA-195は心筋破綻時の代謝を制御しており、Sirtuin3の発現変化とミトコンドリアのタンパク質アセチル化を介している

MicroRNA-195 Regulates Metabolism in Failing Myocardium Via Alterations in Sirtuin 3 Expression and Mitochondrial Protein Acetylation.
  • Xiaokan Zhang
  • Ruiping Ji
  • Xianghai Liao
  • Estibaliz Castillero
  • Peter J Kennel
  • Danielle L Brunjes
  • Marcus Franz
  • Sven Möbius-Winkler
  • Konstantinos Drosatos
  • Isaac George
  • Emily I Chen
  • Paolo C Colombo
  • P Christian Schulze
  • Circulation.2018 05;137(19):2052-2067. CIRCULATIONAHA.117.030486. doi: 10.1161/CIRCULATIONAHA.117.030486.Epub 2018-01-12.

全脳症型クロイツフェルト・ヤコブ病患者における白質変性の病因に関する免疫組織化学的および超構造学的証拠。奇妙なアストロサイトにおける誘導性一酸化窒素合成酵素の過剰発現

Immunohistochemical and ultrastructural evidence for the pathogenesis of white matter degeneration in patients with panencephalopathic-type Creutzfeldt-Jakob disease: Inducible nitric oxide synthase overexpression in bizarre astrocytes.
  • Hiroshi Kohama
  • Masahiro Kusunoki-Ii
  • Kiyota Kato
  • Masako Kato
  • Shinsuke Kato
  • Neuropathology.2020 Apr;doi: 10.1111/neup.12646.Epub 2020-04-01.

血漿中ロイコトリエンEを定量するための高感度液体クロマトグラフィー質量分析法を開発し、ヒトにおける内因性5-LO経路活性の薬理学的抑制を実証した

Development of a highly sensitive liquid chromatography-mass spectrometry method to quantify plasma leukotriene E and demonstrate pharmacological suppression of endogenous 5-LO pathway activity in man.
  • Lars Löfgren
  • Gun-Britt Forsberg
  • Pia Davidsson
  • Susanna Eketjäll
  • Carl Whatling
  • Prostaglandins Other Lipid Mediat..2020 May;150:106463. S1098-8823(20)30056-3. doi: 10.1016/j.prostaglandins.2020.106463.Epub 2020-05-23.

カルノシンはエピジェネティックな制御を介して転写に影響を与えることが、グリオブラストーマ細胞におけるピルビン酸デヒドロゲナーゼキナーゼ4プロモーターのヒストンアセチル化亢進によって実証された

Carnosine influences transcription via epigenetic regulation as demonstrated by enhanced histone acetylation of the pyruvate dehydrogenase kinase 4 promoter in glioblastoma cells.
  • Henry Oppermann
  • Athanasios Alvanos
  • Christiane Seidel
  • Jürgen Meixensberger
  • Frank Gaunitz
  • Amino Acids.2019 Jan;51(1):61-71. 10.1007/s00726-018-2619-2. doi: 10.1007/s00726-018-2619-2.Epub 2018-07-20.

メタンフェタミンの希釈濃度が表層水中に存在すると、魚類の行動障害、世代を超えた毒性、生態系レベルでの影響を引き起こすことが示唆された

Diluted concentrations of methamphetamine in surface water induce behavior disorder, transgenerational toxicity, and ecosystem-level consequences of fish.
  • Zhenglu Wang
  • Kang Mao
  • Wei Du
  • Min Cai
  • Zhaobin Zhang
  • Xiqing Li
  • Water Res..2020 Jul;184:116164. S0043-1354(20)30701-6. doi: 10.1016/j.watres.2020.116164.Epub 2020-07-10.

ゲルマニウム-リン二元系ナノ粒子を多孔質炭素マトリックスに埋め込んだ金属熱還元による高速・安定な大容量電池の開発

Fast and Stable Batteries with High Capacity Enabled by Germanium-Phosphorus Binary Nanoparticles Embedded in a Porous Carbon Matrix via Metallothermic Reduction.
  • Yuhua Yan
  • Jiafeng Ruan
  • Hongyi Xu
  • Ying Xu
  • Yuepeng Pang
  • Junhe Yang
  • Shiyou Zheng
  • ACS Appl Mater Interfaces.2020 May;12(19):21579-21585. doi: 10.1021/acsami.0c01978.Epub 2020-04-30.

最近禁欲した覚せい剤使用者の脳内では、トランスロケーター蛋白質結合の有意な上昇は認められなかった

No significant elevation of translocator protein binding in the brains of recently abstinent methamphetamine users.
  • Edythe D London
  • Kyoji Okita
  • Kaitlin R Kinney
  • Andrew C Dean
  • Megan N McClintick
  • Elizabeth J Rizor
  • Maritza C Johnson
  • Tarannom Mahmoudie
  • Arthur L Brody
  • Erika L Nurmi
  • Lauren C Seaman
  • Judah Farahi
  • Nathaniel Ginder
  • Mark A Mandelkern
  • Drug Alcohol Depend.2020 Jun;213:108104. S0376-8716(20)30269-6. doi: 10.1016/j.drugalcdep.2020.108104.Epub 2020-06-11.

都市部の黒人関節リウマチ患者における悪性腫瘍の有病率

Prevalence of Malignancy Among Urban Black Rheumatoid Arthritis Patients.
  • Isabel M McFarlane
  • Manjeet S Bhamra
  • Abhimnayu Amarnani
  • Su Yien Zhaz
  • Srinivas Kolla
  • Milena Rodriguez Alvarez
  • George Mo
  • Maya Srinivasan
  • Gil Hevroni
  • Talia Meisel
  • Abida Hasan
  • Marie S Baguidy
  • Michael Hadaddin
  • Adielle Melamed
  • Kristaq Koci
  • Nicholas Taklalsingh
  • Joshy Pathiparampil
  • Latoya Freeman
  • Ian Kaplan
  • Naureen Kabani
  • David J Ozeri
  • Elsie Watler
  • Mosab Frefer
  • Vytas Vaitkus
  • Keron Matthew
  • Fray Arroyo-Mercado
  • Helen Lyo
  • Aleksander Feoktistov
  • Randolph Sanchez
  • Faisal Soliman
  • Felix Reyes Valdez
  • Veena Dronamraju
  • Michael Trevisonno
  • Christon Grant
  • Guerrier Clerger
  • Kunfeng Sun
  • Khabbab Amin
  • Makeda Dawkins
  • Jason Green
  • Samir Fahmy
  • Apoorva Jayarangaiah
  • Stephen Anthony Waite
  • Aaliya Burza
  • Int J Clin Res Trials.2020;5(1). 145. doi: 10.15344/2456-8007/2020/145.Epub 2020-04-25.

バルト海の酸性硫酸塩土壌に関連する金属汚染の空間的センチネルとしてのオジロワシ(Haliaeetus albicilla)と大鵜(Phalacrocorax carbo)の巣子

White-tailed eagle (Haliaeetus albicilla) and great cormorant (Phalacrocorax carbo) nestlings as spatial sentinels of Baltic acidic sulphate soil associated metal contamination.
  • R K Vainio
  • I Eulaers
  • T Laaksonen
  • V Vasko
  • V Jormalainen
  • Sci. Total Environ..2020 May;718:137424. S0048-9697(20)30934-7. doi: 10.1016/j.scitotenv.2020.137424.Epub 2020-02-19.

放射性の^{222}Raと^{228}Raビームのクーロン励起からのラジウム原子核の八極子変形の進化

Evolution of Octupole Deformation in Radium Nuclei from Coulomb Excitation of Radioactive ^{222}Ra and ^{228}Ra Beams.
  • P A Butler
  • L P Gaffney
  • P Spagnoletti
  • K Abrahams
  • M Bowry
  • J Cederkäll
  • G de Angelis
  • H De Witte
  • P E Garrett
  • A Goldkuhle
  • C Henrich
  • A Illana
  • K Johnston
  • D T Joss
  • J M Keatings
  • N A Kelly
  • M Komorowska
  • J Konki
  • T Kröll
  • M Lozano
  • B S Nara Singh
  • D O'Donnell
  • J Ojala
  • R D Page
  • L G Pedersen
  • C Raison
  • P Reiter
  • J A Rodriguez
  • D Rosiak
  • S Rothe
  • M Scheck
  • M Seidlitz
  • T M Shneidman
  • B Siebeck
  • J Sinclair
  • J F Smith
  • M Stryjczyk
  • P Van Duppen
  • S Vinals
  • V Virtanen
  • N Warr
  • K Wrzosek-Lipska
  • M Zielińska
  • Phys. Rev. Lett..2020 Jan;124(4):042503. doi: 10.1103/PhysRevLett.124.042503.

半田園地帯や遠隔地における固体燃料燃焼の代替として、廃棄物からエネルギーを取り出すプロセスを利用した直接電気暖房の潜在的な環境上の利点

Potential environmental benefits of direct electric heating powered by waste-to-energy processes as a replacement of solid-fuel combustion in semi-rural and remote areas.
  • Luca Adami
  • Marco Schiavon
  • Elena Cristina Rada
  • Sci. Total Environ..2020 Jun;740:140078. S0048-9697(20)33598-1. doi: 10.1016/j.scitotenv.2020.140078.Epub 2020-06-09.

前脳橈側グリアにおけるリポ蛋白質受容体の欠損は、神経学的欠損と重度の発作をもたらす

Lipoprotein receptor loss in forebrain radial glia results in neurological deficits and severe seizures.
  • Ewa E Bres
  • Dina Safina
  • Julia Müller
  • Peter Bedner
  • Honghong Yang
  • Xavier Helluy
  • Olena Shchyglo
  • Stephan Jansen
  • Melanie D Mark
  • Alexander Esser
  • Christian Steinhäuser
  • Stefan Herlitze
  • Claus U Pietrzik
  • Swetlana Sirko
  • Denise Manahan-Vaughan
  • Andreas Faissner
  • Glia.2020 Jun;doi: 10.1002/glia.23869.Epub 2020-06-24.

包括的メタボローム解析による急性心筋梗塞ラットにおける Shexiang baoxin 錠剤の心保護効果の根底にあるメカニズムを探る

Exploring the mechanism underlying the cardioprotective effect of shexiang baoxin pill on acute myocardial infarction rats by comprehensive metabolomics.
  • Gaosong Wu
  • Linlin Chen
  • Yu Gu
  • Ying Hong
  • Junli Ma
  • Ningning Zheng
  • Jing Zhong
  • Ai-Jun Liu
  • Lili Sheng
  • Weidong Zhang
  • Houkai Li
  • J Ethnopharmacol.2020 Sep;259:113001. S0378-8741(19)34499-X. doi: 10.1016/j.jep.2020.113001.Epub 2020-05-25.

高い加水分解活性を有するグリコーゲン分岐酵素としてのThermotoga maritima MSB8 GH57 α-アミラーゼ AmyCの同定

Identification of Thermotoga maritima MSB8 GH57 α-amylase AmyC as a glycogen-branching enzyme with high hydrolytic activity.
  • Xuewen Zhang
  • Hans Leemhuis
  • Štefan Janeček
  • Mária Martinovičová
  • Tjaard Pijning
  • Marc J E C van der Maarel
  • Appl. Microbiol. Biotechnol..2019 Aug;103(15):6141-6151. 10.1007/s00253-019-09938-1. doi: 10.1007/s00253-019-09938-1.Epub 2019-06-13.

南エチオピアにおける妊娠第3期の身体活動レベルおよびその他の妊産婦の特徴、およびその関連性。プロスペクティブ・コホート研究

Level of physical activity and other maternal characteristics during the third trimester of pregnancy and its association with birthweight at term in South Ethiopia: A prospective cohort study.
  • Meseret Legesse
  • Jemal Haider Ali
  • Md Dilshad Manzar
  • Mohammed Salahuddin
  • Hamid Yimam Hassen
  • PLoS ONE.2020;15(7):e0236136. PONE-D-20-09704. doi: 10.1371/journal.pone.0236136.Epub 2020-07-20.

RNAポリメラーゼIII関連白血病の表現型と分子スペクトルの拡大

Expanding the phenotypic and molecular spectrum of RNA polymerase III-related leukodystrophy.
  • Stefanie Perrier
  • Laurence Gauquelin
  • Catherine Fallet-Bianco
  • Megan K Dishop
  • Mackenzie A Michell-Robinson
  • Luan T Tran
  • Kether Guerrero
  • Lama Darbelli
  • Myriam Srour
  • Kevin Petrecca
  • Deborah L Renaud
  • Michael Saito
  • Seth Cohen
  • Steffen Leiz
  • Bader Alhaddad
  • Tobias B Haack
  • Ingrid Tejera-Martin
  • Fernando I Monton
  • Norberto Rodriguez-Espinosa
  • Daniela Pohl
  • Savithri Nageswaran
  • Annette Grefe
  • Emma Glamuzina
  • Geneviève Bernard
  • Neurol Genet.2020 Jun;6(3):e425. NG2019012377. doi: 10.1212/NXG.0000000000000425.Epub 2020-05-11.

肝臓特異的Prknノックアウトマウスは、食事誘発性肝性ステアトーシスおよびインスリン抵抗性に対してより感受性が高い

Liver-specific Prkn knockout mice are more susceptible to diet-induced hepatic steatosis and insulin resistance.
  • Lia R Edmunds
  • Bingxian Xie
  • Amanda M Mills
  • Brydie R Huckestein
  • Ramya Undamatla
  • Anjana Murali
  • Martha M Pangburn
  • James Martin
  • Ian Sipula
  • Brett A Kaufman
  • Iain Scott
  • Michael J Jurczak
  • Mol Metab.2020 Jul;:101051. S2212-8778(20)30125-3. doi: 10.1016/j.molmet.2020.101051.Epub 2020-07-09.

プロトカテキン酸は、筋萎縮性側索硬化症のhSOD1マウスモデルにおける生存期間を延長し、運動機能を改善し、グリア症を減少させ、神経筋接合部を維持する

Protocatechuic Acid Extends Survival, Improves Motor Function, Diminishes Gliosis, and Sustains Neuromuscular Junctions in the hSOD1 Mouse Model of Amyotrophic Lateral Sclerosis.
  • Lilia A Koza
  • Aimee N Winter
  • Jessica Holsopple
  • Angela N Baybayon-Grandgeorge
  • Claudia Pena
  • Jeffrey R Olson
  • Randall C Mazzarino
  • David Patterson
  • Daniel A Linseman
  • Nutrients.2020 Jun;12(6). E1824. doi: 10.3390/nu12061824.Epub 2020-06-18.

化学療法誘発性疼痛性末梢神経障害患者に対するセロトニン-ノルエピネフリン再取り込み阻害薬の効果。メタアナリシス

Effect of serotonin-norepinephrine reuptake inhibitors for patients with chemotherapy-induced painful peripheral neuropathy: A meta-analysis.
  • Soo Youn Song
  • Young Bok Ko
  • Hyeun Kim
  • Geon Woo Lee
  • Jung Bo Yang
  • Ha Kyun Chang
  • Sang Mi Kwak
  • Jaeyun Jung
  • Siyeo Lee
  • Sun Yeul Lee
  • Heon Jong Yoo
  • Medicine (Baltimore).2020 Jan;99(1):e18653. 00005792-202001030-00066. doi: 10.1097/MD.0000000000018653.

ORCA/LRWD1はヘテロクロマチン組織を制御することでALTテロメアにおける相同組換えを制御している

ORCA/LRWD1 Regulates Homologous Recombination at ALT-Telomeres by Modulating Heterochromatin Organization.
  • Rosaline Y C Hsu
  • Yo-Chuen Lin
  • Christophe Redon
  • Qinyu Sun
  • Deepak K Singh
  • Yating Wang
  • Vasudha Aggarwal
  • Jaba Mitra
  • Abhijith Matur
  • Branden Moriarity
  • Taekjip Ha
  • Mirit I Aladjem
  • Kannanganattu V Prasanth
  • Supriya G Prasanth
  • iScience.2020 May;23(5):101038. S2589-0042(20)30222-4. doi: 10.1016/j.isci.2020.101038.Epub 2020-04-18.

脳卒中患者における上肢の痙縮と機能性の改善に対する体外衝撃波治療の有効性:システマティックレビューおよびメタアナリシス

The effectiveness of extracorporeal shock wave therapy for improving upper limb spasticity and functionality in stroke patients: a systematic review and meta-analysis.
  • Rosa Cabanas-Valdés
  • Pol Serra-Llobet
  • Pere Ramón Rodriguez-Rubio
  • Carlos López-de-Celis
  • Mercé Llauró-Fores
  • Jordi Calvo-Sanz
  • Clin Rehabil.2020 Jun;:269215520932196. doi: 10.1177/0269215520932196.Epub 2020-06-08.

転移性非小細胞肺がん患者の治療で達成された進歩は高齢者にも届くか?スイス東部のがんセンターによるコホート研究

Does progress achieved in the treatment of patients with metastatic non-small-cell lung cancer reach the elderly population? A cohort study from a cancer centre from Eastern Switzerland.
  • Sabine Schmid
  • Jorune Suipyte
  • Christian Herrmann
  • Mohsen Mousavi
  • Felicitas Hitz
  • Martin Früh
  • Eur J Cancer Care (Engl).2020 Mar;29(2):e13206. doi: 10.1111/ecc.13206.Epub 2020-01-21.

毛様体メラニン濃縮ホルモン受容体1(MCHR1)は、マウスの中枢神経系に広く分布しており、性に依存しない形で分布していることが明らかになった

Ciliary melanin-concentrating hormone receptor 1 (MCHR1) is widely distributed in the murine CNS in a sex-independent manner.
  • Giovanne B Diniz
  • Daniella S Battagello
  • Marianne O Klein
  • Bianca S M Bono
  • Jozélia G P Ferreira
  • Livia C Motta-Teixeira
  • Jessica C G Duarte
  • Françoise Presse
  • Jean-Louis Nahon
  • Antoine Adamantidis
  • Melissa J Chee
  • Luciane V Sita
  • Jackson C Bittencourt
  • J. Neurosci. Res..2020 Jun;doi: 10.1002/jnr.24651.Epub 2020-06-12.

マイクロスケール添加剤製造による金属。微細構造と機械的特性の比較

Metals by Micro-Scale Additive Manufacturing: Comparison of Microstructure and Mechanical Properties.
  • Alain Reiser
  • Lukas Koch
  • Kathleen A Dunn
  • Toshiki Matsuura
  • Futoshi Iwata
  • Ofer Fogel
  • Zvi Kotler
  • Nanjia Zhou
  • Kristin Charipar
  • Alberto Piqué
  • Patrik Rohner
  • Dimos Poulikakos
  • Sanghyeon Lee
  • Seung Kwon Seol
  • Ivo Utke
  • Cathelijn van Nisselroy
  • Tomaso Zambelli
  • Jeffrey M Wheeler
  • Ralph Spolenak
  • Adv Funct Mater.2020 Jul;30(28):1910491. ADFM201910491. doi: 10.1002/adfm.201910491.Epub 2020-05-25.

静脈リザーバーと真空補助静脈ドレナージレベルを変化させた新生児心肺バイパス回路におけるCapiox FX05およびRX05酸素吸入器のin vitro評価

In vitro evaluation of Capiox FX05 and RX05 oxygenators in neonatal cardiopulmonary bypass circuits with varying venous reservoir and vacuum-assisted venous drainage levels.
  • Shyama Sathianathan
  • Rafay Nasir
  • Shigang Wang
  • Allen R Kunselman
  • Akif Ündar
  • Artif Organs.2020 Jan;44(1):28-39. doi: 10.1111/aor.13404.Epub 2019-01-14.

地中海式の食事パターンは、アンドロゲン遮断療法を受けた前立腺がん男性のがん関連疲労と生活の質を改善する。パイロットランダム化対照試験

Mediterranean-style dietary pattern improves cancer-related fatigue and quality of life in men with prostate cancer treated with androgen deprivation therapy: A pilot randomised control trial.
  • Brenton J Baguley
  • Tina L Skinner
  • David G Jenkins
  • Olivia R L Wright
  • Clin Nutr.2020 May;S0261-5614(20)30250-8. doi: 10.1016/j.clnu.2020.05.016.Epub 2020-05-25.

成人喘息患者における自己申告による鼻腔内過反応の有病率と誘因

Prevalence and triggers of self-reported nasal hyperreactivity in adults with asthma.
  • Jef Feijen
  • Sven F Seys
  • Brecht Steelant
  • Dominique M A Bullens
  • Lieven J Dupont
  • Maria García-Cruz
  • Alejandro Jimenez-Chobillón
  • Désirée Larenas-Linnemann
  • Laura Van Gerven
  • Wytske J Fokkens
  • Ioana Agache
  • Peter W Hellings
  • World Allergy Organ J.2020 Jun;13(6):100132. S1939-4551(20)30035-1. doi: 10.1016/j.waojou.2020.100132.Epub 2020-07-01.

血液ソーセージに関連した侵襲性リステリア症の全国的大規模アウトブレイク、ドイツ、2018-2019年

Large Nationwide Outbreak of Invasive Listeriosis Associated with Blood Sausage, Germany, 2018-2019.
  • Sven Halbedel
  • Hendrik Wilking
  • Alexandra Holzer
  • Sylvia Kleta
  • Martin A Fischer
  • Stefanie Lüth
  • Ariane Pietzka
  • Steliana Huhulescu
  • Raskit Lachmann
  • Amrei Krings
  • Werner Ruppitsch
  • Alexandre Leclercq
  • Rolf Kamphausen
  • Maylin Meincke
  • Christiane Wagner-Wiening
  • Matthias Contzen
  • Iris Barbara Kraemer
  • Sascha Al Dahouk
  • Franz Allerberger
  • Klaus Stark
  • Antje Flieger
  • Emerging Infect. Dis..2020 Jul;26(7):1456-1464. doi: 10.3201/eid2607.200225.

超分子重合による凝集誘起発光を有する発光性超分子集合体の簡便な構築とその生物学的イメージング

Facile construction of luminescent supramolecular assemblies with aggregation-induced emission feature through supramolecular polymerization and their biological imaging.
  • Lili Guo
  • Dazhuang Xu
  • Long Huang
  • Meiying Liu
  • Hongye Huang
  • Jianwen Tian
  • Ruming Jiang
  • Yuanqing Wen
  • Xiaoyong Zhang
  • Yen Wei
  • Mater Sci Eng C Mater Biol Appl.2018 Apr;85:233-238. S0928-4931(17)32713-3. doi: 10.1016/j.msec.2017.12.031.Epub 2018-01-03.

遺伝学的手法を用いたゲノムワイドなmiRNAベースのSSRマーカーの開発とグラミネア/非グラミネアの種への移植性の解析

Genome-wide development of miRNA-based SSR markers in Cleistogenes songorica and analysis of their transferability to Gramineae/non-Gramineae species.
  • Gisele Kanzana
  • Yufei Zhang
  • Tiantian Ma
  • Wenxian Liu
  • Fan Wu
  • Qi Yan
  • Xueyang Min
  • Zhuanzhuan Yan
  • Blaise Pascal Muvunyi
  • Jie Li
  • Zhengshe Zhang
  • Yufeng Zhao
  • Jiyu Zhang
  • J. Appl. Genet..2020 Jun;10.1007/s13353-020-00561-9. doi: 10.1007/s13353-020-00561-9.Epub 2020-06-07.

3,3-ジフルオロ化テトラヒドロピリジノール化合物がCDK7を介したCdc2のリン酸化を阻害し、細胞周期停止を介して作用する肝細胞癌の新規抗腫瘍剤であることを明らかにした

Identification of a 3,3-difluorinated tetrahydropyridinol compound as a novel antitumor agent for hepatocellular carcinoma acting via cell cycle arrest through disturbing CDK7-mediated phosphorylation of Cdc2.
  • Wu Bi
  • Ji-Chang Xiao
  • Rui-Jie Liu
  • Liu-Ying Zhou
  • Sai Zhang
  • Mei Yang
  • Peng-Fei Zhang
  • Invest New Drugs.2020 04;38(2):287-298. 10.1007/s10637-019-00792-6. doi: 10.1007/s10637-019-00792-6.Epub 2019-05-11.

CRISPR/Cas9を介在させたゲノム編集マウスにより、精巣に濃縮された10個の遺伝子が男性の繁殖には不要な遺伝子であることが明らかになった

CRISPR/Cas9-mediated genome-edited mice reveal 10 testis-enriched genes are dispensable for male fecundity.
  • Soojin Park
  • Keisuke Shimada
  • Yoshitaka Fujihara
  • Zoulan Xu
  • Kentaro Shimada
  • Tamara Larasati
  • Putri Pratiwi
  • Ryan M Matzuk
  • Darius J Devlin
  • Zhifeng Yu
  • Thomas X Garcia
  • Martin M Matzuk
  • Masahito Ikawa
  • Biol. Reprod..2020 May;ioaa084. doi: 10.1093/biolre/ioaa084.Epub 2020-05-26.

COVID-19 パンデミック時の個人用保護具の病院前での適切な使用を教える。ゲーム化されたe-ラーニングモジュールの開発

Teaching Adequate Prehospital Use of Personal Protective Equipment During the COVID-19 Pandemic: Development of a Gamified e-Learning Module.
  • Mélanie Suppan
  • Birgit Gartner
  • Eric Golay
  • Loric Stuby
  • Marion White
  • Philippe Cottet
  • Mohamed Abbas
  • Anne Iten
  • Stephan Harbarth
  • Laurent Suppan
  • JMIR Serious Games.2020 Jun;8(2):e20173. v8i2e20173. doi: 10.2196/20173.Epub 2020-06-12.