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日本語AIでPubMedを検索

日本語AIでPubMedを検索

PubMedの提供する医学論文データベースを日本語で検索できます。AI(Deep Learning)を活用した機械翻訳エンジンにより、精度高く日本語へ翻訳された論文をご参照いただけます。

みんなが読んでいる論文

ニンジン(Daucus carota)における2つのζ-カロテンデサチュラーゼパラログの役割の違い。ZDS1 は、植物の発生とカロテノイド合成に不可欠な機能性遺伝子です

Differential role of the two ζ-carotene desaturase paralogs in carrot (Daucus carota): ZDS1 is a functional gene essential for plant development and carotenoid synthesis.
  • Carlos Flores-Ortiz
  • Lilia M Alvarez
  • Alejandro Undurraga
  • Daniela Arias
  • Felipe Durán
  • Guillermo Wegener
  • Claudia Stange
  • Plant Sci..2020 Feb;291:110327. S0168-9452(19)31500-6. doi: 10.1016/j.plantsci.2019.110327.Epub 2019-11-26.

角膜内皮再生のための生分解性および生体適合性のあるポリエチレングリコールベースのハイドロゲルフィルム

Biodegradable and biocompatible poly(ethylene glycol)-based hydrogel films for the regeneration of corneal endothelium.
  • Berkay Ozcelik
  • Karl D Brown
  • Anton Blencowe
  • Katharina Ladewig
  • Geoffrey W Stevens
  • Jean-Pierre Y Scheerlinck
  • Keren Abberton
  • Mark Daniell
  • Greg G Qiao
  • Adv Healthc Mater.2014 Sep;3(9):1496-507. doi: 10.1002/adhm.201400045.Epub 2014-03-20.

アルジェリアの中央草原Djelfaにおける子羊におけるジアルジア・デュオデナリスの発生と分子特性

Occurrence and molecular characterization of Giardia duodenalis in lambs in Djelfa, the central steppe of Algeria.
  • Soumaya Benhassine
  • Djamel Baroudi
  • Ahcene Hakem
  • Myriam Thomas
  • AbdElkarim Laatamna
  • Salem Belkessa
  • Yaoyu Feng
  • Dawn Roellig
  • Xiaohua Chen
  • Karim Tarik Adjou
  • Lihua Xiao
  • Parasitol. Res..2020 Jul;10.1007/s00436-020-06808-y. doi: 10.1007/s00436-020-06808-y.Epub 2020-07-14.

無精子症ドナーからの精液血漿中のプロタミンの定量を調査した研究。閉塞性無精子症の診断、精巣精子採取(TESE)や人工授精精子注入(ICSI)のための出産精子の採取に向けた新たな方法の提案

The study investigating the determination of protamine in seminal plasma from azoospermic donors: Suggestion of new methods to diagnose obstructive azoospermia, and to capture childbearing sperm for testicular sperm extraction (TESE) and insemination sperm injection (ICSI).
  • Masatoki Katayama
  • Satoru Kaneko
  • Takahiro Tsukimura
  • Kiyoshi Takamatsu
  • Tadayasu Togawa
  • Anal. Biochem..2020 Jul;604:113792. S0003-2697(20)30324-9. doi: 10.1016/j.ab.2020.113792.Epub 2020-07-02.

Tie2の活性化は、ヒトのセプシスにおける内皮グリコカリックスの保護と再構成を促進する

Tie2 Activation Promotes Protection and Reconstitution of the Endothelial Glycocalyx in Human Sepsis.
  • Carolin Christina Drost
  • Alexandros Rovas
  • Kristina Kusche-Vihrog
  • Paul Van Slyke
  • Harold Kim
  • Van C Hoang
  • Jason T Maynes
  • Dirk Oliver Wennmann
  • Hermann Pavenstädt
  • Wolfgang Linke
  • Alexander Lukasz
  • Bettina Hesse
  • Philipp Kümpers
  • Thromb. Haemost..2019 Nov;119(11):1827-1838. doi: 10.1055/s-0039-1695768.Epub 2019-09-07.

前立腺閉塞の二次的な下部尿路症状に対する前立腺のバイポーラ対モノポーラ経尿道的切除。コクランレビュー

Bipolar vs. monopolar transurethral resection of the prostate for lower urinary tract symptoms secondary to benign prostatic obstruction: A Cochrane review.
  • Cameron Edwin Alexander
  • Malo M F Scullion
  • Muhammad Imran Omar
  • Yuhong Yuan
  • Charalampos Mamoulakis
  • James M O N'Dow
  • Changhao Chen
  • Thomas B L Lam
  • Can Urol Assoc J.2020 Jun;cuaj.6464. doi: 10.5489/cuaj.6464.Epub 2020-06-16.

3D-QSAR、分子ドッキング、分子動力学シミュレーションを用いて、新規な(5-イミダゾール-2-イル-4-フェニルピリミジン-2-イル)2-(2-ピリジルアミノ)エチルアミン誘導体のグリコーゲン合成キナーゼ3阻害剤としてのインシリコデザインを行った

In silico design novel (5-imidazol-2-yl-4-phenylpyrimidin-2-yl)[2-(2-pyridylamino)ethyl]amine derivatives as inhibitors for glycogen synthase kinase 3 based on 3D-QSAR, molecular docking and molecular dynamics simulation.
  • Qingxiu He
  • Chu Han
  • Guangping Li
  • Haiqiong Guo
  • Yuxuan Wang
  • Yong Hu
  • Zhihua Lin
  • Yuanqiang Wang
  • Comput Biol Chem.2020 Jul;88:107328. S1476-9271(20)30643-5. doi: 10.1016/j.compbiolchem.2020.107328.Epub 2020-07-04.

UAE1 阻害は膵臓癌におけるアンフォールドタンパク応答、DNA 損傷、カスパーゼ依存性細胞死を媒介する

UAE1 inhibition mediates the unfolded protein response, DNA damage and caspase-dependent cell death in pancreatic cancer.
  • Yajing Liu
  • Sahezeel Awadia
  • Amy Delaney
  • Merna Sitto
  • Carl Engelke
  • Heli Patel
  • Andrew Calcaterra
  • Sylvia Zelenka-Wang
  • Hojin Lee
  • Joseph Contessa
  • Nouri Neamati
  • Mats Ljungman
  • Theodore S Lawrence
  • Meredith A Morgan
  • Alnawaz Rehemtulla
  • Transl Oncol.2020 Jul;13(11):100834. S1936-5233(20)30326-0. doi: 10.1016/j.tranon.2020.100834.Epub 2020-07-17.

放射線科での偶発的なCOVID-19。乳がんのCT病期分類を受けた無症候性患者におけるCOVID-19の放射線所見

Incidental COVID-19 in the radiology department: Radiographic findings of COVID-19 in asymptomatic patient undergoing CT staging for breast cancer.
  • Kevin Yoo
  • Robert Y Choi
  • Justin Sun
  • Clinton Veselis
  • Bhishak Kamat
  • Maruti Kumaran
  • Omar Agosto
  • Hillel S Maresky
  • Radiol Case Rep.2020 Sep;15(9):1614-1617. S1930-0433(20)30274-0. doi: 10.1016/j.radcr.2020.05.080.Epub 2020-06-11.

健康なボランティアを対象としたAZD5718の第1相薬物動態試験。ロスバスタチンとの併用投与、製剤および食品の経口バイオアベイラビリティーへの影響

Phase 1 Pharmacokinetic Study of AZD5718 in Healthy Volunteers: Effects of Coadministration With Rosuvastatin, Formulation and Food on Oral Bioavailability.
  • Hans Ericsson
  • Karin Nelander
  • Maria Heijer
  • Magnus Kjaer
  • Eva-Lotte Lindstedt
  • Muna Albayaty
  • Pablo Forte
  • Maria Lagerström-Fermér
  • Stanko Skrtic
  • Clin Pharmacol Drug Dev.2020 Apr;9(3):411-421. doi: 10.1002/cpdd.756.Epub 2019-12-02.

同じ一次切除標本によく分化した甲状腺がんと退形成性甲状腺がんが共存していること:13例の連続したシリーズにおける2つの成分の免疫フェノタイプおよび遺伝学的比較、および文献のレビュー

Coexisting well-differentiated and anaplastic thyroid carcinoma in the same primary resection specimen: immunophenotypic and genetic comparison of the two components in a consecutive series of 13 cases and a review of the literature.
  • Moira Ragazzi
  • Federica Torricelli
  • Benedetta Donati
  • Alessia Ciarrocchi
  • Dario de Biase
  • Giovanni Tallini
  • Eleonora Zanetti
  • Alessandra Bisagni
  • Elisabetta Kuhn
  • Davide Giordano
  • Andrea Frasoldati
  • Simonetta Piana
  • Virchows Arch..2020 Jul;10.1007/s00428-020-02891-9. doi: 10.1007/s00428-020-02891-9.Epub 2020-07-18.

東南アジアにおけるマラリア予防のためのナフトキン-アジスロマイシン共剤の有効性と安全性。第 3 相、二重盲検、無作為化、プラセボ対照試験

Efficacy and Safety of a Naphthoquine-Azithromycin Co-Formulation for Malaria Prophylaxis in Southeast Asia: A Phase 3, Double-Blind, Randomized, Placebo-Controlled Trial.
  • Henglin Yang
  • Jingyan Wang
  • Hui Liu
  • Yan Zhao
  • Seetha Lakshmi
  • Xingliang Li
  • Renhua Nie
  • Chunfu Li
  • Hengye Wang
  • Yaming Cao
  • Lynette Menezes
  • Liwang Cui
  • Clin. Infect. Dis..2020 Jul;ciaa1018. doi: 10.1093/cid/ciaa1018.Epub 2020-07-20.

職人的・小規模な金採掘(ASGM)活動の影響を受けた土壌における銅、鉛、亜鉛、ヒ素の固相分離と放出保持メカニズム

Solid-phase partitioning and release-retention mechanisms of copper, lead, zinc and arsenic in soils impacted by artisanal and small-scale gold mining (ASGM) activities.
  • Carlito Baltazar Tabelin
  • Marthias Silwamba
  • Florifern C Paglinawan
  • Alissa Jane S Mondejar
  • Ho Gia Duc
  • Vannie Joy Resabal
  • Einstine M Opiso
  • Toshifumi Igarashi
  • Shingo Tomiyama
  • Mayumi Ito
  • Naoki Hiroyoshi
  • Mylah Villacorte-Tabelin
  • Chemosphere.2020 Jul;260:127574. S0045-6535(20)31769-0. doi: 10.1016/j.chemosphere.2020.127574.Epub 2020-07-10.

ミグラスタットによる治療を受けた成人ニーマン・ピック病C型患者における嚥下障害と嚥下機能の縦断的変化の特徴付け

Characterization of Dysphagia and Longitudinal Changes in Swallowing Function in Adults with Niemann-Pick Disease Type C Treated with Miglustat.
  • Courtney Lewis
  • Megan Keage
  • Miyuki Watanabe
  • Danielle Schubiger
  • Dennis Velakoulis
  • Mark Walterfang
  • Adam P Vogel
  • Dysphagia.2020 Jun;10.1007/s00455-020-10145-8. doi: 10.1007/s00455-020-10145-8.Epub 2020-06-19.

インドのプライマリケアにおける重度のうつ病に対するカウンセラーによる短時間の心理的治療であるヘルシーアクティビティプログラム(HAP):無作為化比較試験

The Healthy Activity Program (HAP), a lay counsellor-delivered brief psychological treatment for severe depression, in primary care in India: a randomised controlled trial.
  • Vikram Patel
  • Benedict Weobong
  • Helen A Weiss
  • Arpita Anand
  • Bhargav Bhat
  • Basavraj Katti
  • Sona Dimidjian
  • Ricardo Araya
  • Steve D Hollon
  • Michael King
  • Lakshmi Vijayakumar
  • A-La Park
  • David McDaid
  • Terry Wilson
  • Richard Velleman
  • Betty R Kirkwood
  • Christopher G Fairburn
  • Lancet.2017 01;389(10065):176-185. S0140-6736(16)31589-6. doi: 10.1016/S0140-6736(16)31589-6.Epub 2016-12-15.

YBX1はp110βを標的とすることでオートファジーを仲介し、NSCLCにおけるシスプラチン感受性を低下させています

YBX1 mediates autophagy by targeting p110β and decreasing the sensitivity to cisplatin in NSCLC.
  • Yanwei Cui
  • Fengzhou Li
  • Qiang Xie
  • Shilei Zhao
  • Tao Guo
  • Ping Guo
  • Sheng Hu
  • Jiaojiao Hao
  • Chunfang Tian
  • Wendan Yu
  • Zhuoshi Li
  • Lei Fang
  • Lei Zhao
  • Manyu Chen
  • Taihua Wu
  • Chundong Gu
  • Cell Death Dis.2020 Jun;11(6):476. 10.1038/s41419-020-2555-4. doi: 10.1038/s41419-020-2555-4.Epub 2020-06-19.

リン酸化プロテオーム解析により、CLK1 が胃癌の新規治療標的であることが明らかになった

Phosphoproteomic analysis identifies CLK1 as a novel therapeutic target in gastric cancer.
  • Niraj Babu
  • Sneha M Pinto
  • Manjusha Biswas
  • Tejaswini Subbannayya
  • Manoj Rajappa
  • Sonali V Mohan
  • Jayshree Advani
  • Pavithra Rajagopalan
  • Gajanan Sathe
  • Nazia Syed
  • Vinod D Radhakrishna
  • Oliyarasi Muthusamy
  • Sanjay Navani
  • Rekha V Kumar
  • Gopal Gopisetty
  • Thangarajan Rajkumar
  • Padhma Radhakrishnan
  • Saravanan Thiyagarajan
  • Akhilesh Pandey
  • Harsha Gowda
  • Pradip Majumder
  • Aditi Chatterjee
  • Gastric Cancer.2020 Apr;10.1007/s10120-020-01062-8. doi: 10.1007/s10120-020-01062-8.Epub 2020-04-24.

気管支肺胞液中の単純ヘルペスウイルス 1 型患者の機械換気患者の転帰に及ぼす抗ウイルス療法の効果:レトロスペクティブコホート研究

Effect of antiviral therapy on the outcome of mechanically ventilated patients with herpes simplex virus type 1 in bronchoalveolar lavage fluid: a retrospective cohort study.
  • Elisabeth Heimes
  • Michael Baier
  • Christina Forstner
  • Sebastian Weis
  • Michael Bauer
  • Michael Fritzenwanger
  • André Scherag
  • Mathias W Pletz
  • Miriam Kesselmeier
  • Stefan Hagel
  • Chest.2020 Jul;S0012-3692(20)31854-7. doi: 10.1016/j.chest.2020.06.056.Epub 2020-07-03.

チモロールマレイン酸塩を担持した第四級キトサン系感熱性ハイドロゲルの合成と特性:緑内障治療のための透明な外用眼球送達システム

Synthesis and characterization of timolol maleate-loaded quaternized chitosan-based thermosensitive hydrogel: A transparent topical ocular delivery system for the treatment of glaucoma.
  • Yousef Pakzad
  • Marziyeh Fathi
  • Yadollah Omidi
  • Masoud Mozafari
  • Ali Zamanian
  • Int. J. Biol. Macromol..2020 May;159:117-128. S0141-8130(20)33145-7. doi: 10.1016/j.ijbiomac.2020.04.274.Epub 2020-05-05.

DUODENAL-JEJUNAL BYPASSが視床下部肥満ラットの褐色付着部における脂質蓄積を減少させることを明らかにした

DUODENAL-JEJUNAL BYPASS REDUCES LIPID ACCUMULATION IN THE BROWN ADIPOSE TISSUE OF HYPOTHALAMIC OBESE RATS.
  • Vanessa Marieli Ceglarek
  • Zoé Maria Guareschi
  • Gabriela Moreira-Soares
  • Rafaela Cristiane Ecker-Passarello
  • Sandra Lucinei Balbo
  • Maria Lúcia Bonfleur
  • Sabrina Grassiolli
  • Arq Bras Cir Dig.2020 Jul;33(1):e1497. S0102-67202020000100307. doi: 10.1590/0102-672020190001e1497.

α-シヌクレイン神経毒性のリピドミクス解析によりステアロイルCoAデサチュラーゼをパーキンソン治療の標的として同定

Lipidomic Analysis of α-Synuclein Neurotoxicity Identifies Stearoyl CoA Desaturase as a Target for Parkinson Treatment.
  • Saranna Fanning
  • Aftabul Haque
  • Thibaut Imberdis
  • Valeriya Baru
  • M Inmaculada Barrasa
  • Silke Nuber
  • Daniel Termine
  • Nagendran Ramalingam
  • Gary P H Ho
  • Tallie Noble
  • Jackson Sandoe
  • Yali Lou
  • Dirk Landgraf
  • Yelena Freyzon
  • Gregory Newby
  • Frank Soldner
  • Elizabeth Terry-Kantor
  • Tae-Eun Kim
  • Harald F Hofbauer
  • Michel Becuwe
  • Rudolf Jaenisch
  • David Pincus
  • Clary B Clish
  • Tobias C Walther
  • Robert V Farese
  • Supriya Srinivasan
  • Michael A Welte
  • Sepp D Kohlwein
  • Ulf Dettmer
  • Susan Lindquist
  • Dennis Selkoe
  • Mol. Cell.2019 03;73(5):1001-1014.e8. S1097-2765(18)30998-5. doi: 10.1016/j.molcel.2018.11.028.Epub 2018-12-04.

完全磁気浮上式の小型遠心式左室補助装置の脈動運転下での血行動態性能。脈動運転下での完全磁気浮上式小型遠心式左室補助装置の血行動態性能:in vitro試験

Hemodynamic performance of a compact centrifugal left ventricular assist device with fully magnetic levitation under pulsatile operation: An in vitro study.
  • Tingting Wu
  • Hao Lin
  • Yuxin Zhu
  • Penghui Huang
  • Frank Lin
  • Chen Chen
  • Po-Lin Hsu
  • Proc Inst Mech Eng H.2020 Jul;:954411920937919. doi: 10.1177/0954411920937919.Epub 2020-07-10.

均一な粒子径とユニークな輸送タンパク質関連タンパク質コロナを持つFe/Mg修飾炭酸アパタイトは、乳がん細胞にドキソルビシンを効率的に送達する

Fe/Mg-Modified Carbonate Apatite with Uniform Particle Size and Unique Transport Protein-Related Protein Corona Efficiently Delivers Doxorubicin into Breast Cancer Cells.
  • Sheikh Tanzina Haque
  • Md Emranul Karim
  • Syafiq Asnawi Zainal Abidin
  • Iekhsan Othman
  • Mark M Banaszak Holl
  • Ezharul Hoque Chowdhury
  • Nanomaterials (Basel).2020 Apr;10(5). E834. doi: 10.3390/nano10050834.Epub 2020-04-27.

間葉系幹細胞由来の生体適合性膜ベシクルは、ヒト単核球の活性化と増殖を抑制する免疫調節活性を示す

Mesenchymal Stem Cell Derived Biocompatible Membrane Vesicles Demonstrate Immunomodulatory Activity Inhibiting Activation and proliferation of Human Mononuclear Cells.
  • Marina O Gomzikova
  • Sevindzh K Kletukhina
  • Sirina V Kurbangaleeva
  • Olga A Neustroeva
  • Olga S Vasileva
  • Ekaterina E Garanina
  • Svetlana F Khaiboullina
  • Albert A Rizvanov
  • Pharmaceutics.2020 Jun;12(6). E577. doi: 10.3390/pharmaceutics12060577.Epub 2020-06-23.

COVID-19患者に対する回復期血漿または高免疫性免疫グロブリン:生きたシステマティックレビュー

Convalescent plasma or hyperimmune immunoglobulin for people with COVID-19: a living systematic review.
  • Vanessa Piechotta
  • Khai Li Chai
  • Sarah J Valk
  • Carolyn Doree
  • Ina Monsef
  • Erica M Wood
  • Abigail Lamikanra
  • Catherine Kimber
  • Zoe McQuilten
  • Cynthia So-Osman
  • Lise J Estcourt
  • Nicole Skoetz
  • Cochrane Database Syst Rev.2020 07;7:CD013600. doi: 10.1002/14651858.CD013600.pub2.Epub 2020-07-10.

クルクミンによるGSK-3β阻害は、ヒト神経芽腫細胞において、TFEBの活性化と抗酸化活性を介してアミロイド生成を抑制します

GSK-3β inhibition by curcumin mitigates amyloidogenesis via TFEB activation and anti-oxidative Activity in human neuroblastoma cells.
  • Hyun-Chul Song
  • Yubing Chen
  • Yingqing Chen
  • Jeongmin Park
  • Min Zheng
  • Young-Joon Surh
  • Uh-Hyun Kim
  • Jeong Woo Park
  • Rina Yu
  • Hun Taeg Chung
  • Yeonsoo Joe
  • Free Radic. Res..2020 Jul;:1-39. doi: 10.1080/10715762.2020.1791843.Epub 2020-07-06.

慢性HBV感染症患者におけるB型肝炎表面抗原のウイルス特異的およびグローバルT細胞に対する効果

Effects of Hepatitis B Surface Antigen on Virus-specific and Global T Cells in Patients With Chronic HBV infection.
  • Nina Le Bert
  • Upkar S Gill
  • Michelle Hong
  • Kamini Kunasegaran
  • Damien Z M Tan
  • Raidah Ahmad
  • Yang Cheng
  • Charles-A Dutertre
  • Andreas Heinecke
  • Laura Rivino
  • Anthony Tan
  • Navjyot K Hansi
  • Min Zhang
  • Sujuan Xi
  • Yutian Chong
  • Stefan Pflanz
  • Evan W Newell
  • Patrick T F Kennedy
  • Antonio Bertoletti
  • Gastroenterology.2020 Apr;S0016-5085(20)30492-3. doi: 10.1053/j.gastro.2020.04.019.Epub 2020-04-14.

非骨髄芽腫性β-サラサラ血症マウスにおけるβ-サラサラ血症患者由来の遺伝的に補正されたiPSCの安全性と有効性

The safety and effectiveness of genetically corrected iPSCs derived from β-thalassaemia patients in nonmyeloablative β-thalassaemic mice.
  • Yexing Xian
  • Yingjun Xie
  • Bing Song
  • Zhanhui Ou
  • Shuming Ouyang
  • Yuhuan Xie
  • Yi Yang
  • Zeyu Xiong
  • Haoxian Li
  • Xiaofang Sun
  • Stem Cell Res Ther.2020 Jul;11(1):288. 10.1186/s13287-020-01765-w. doi: 10.1186/s13287-020-01765-w.Epub 2020-07-16.

脳微小透析研究のためのバイオマトリックス中の物理化学的特性と未結合画分に基づく中枢神経系薬剤候補の除外

Exclusion of unsuitable CNS drug candidates based on their physicochemical properties and unbound fractions in biomatrices for brain microdialysis investigations.
  • Qianwen Wang
  • Tianjing Ren
  • Jiajia Zhao
  • Chun-Ho Wong
  • H Y Edwin Chan
  • Zhong Zuo
  • J Pharm Biomed Anal.2020 Jan;178:112946. S0731-7085(19)30281-X. doi: 10.1016/j.jpba.2019.112946.Epub 2019-10-25.

Brachiaria brizanthaへのEnterolobium cyclocarpumポッドおよびGliricidia sepium飼料の添加が乾物分解、揮発性脂肪酸濃度、およびin vitroメタン生産に及ぼす影響

Effect of the addition of Enterolobium cyclocarpum pods and Gliricidia sepium forage to Brachiaria brizantha on dry matter degradation, volatile fatty acid concentration, and in vitro methane production.
  • Isabel Cristina Molina-Botero
  • Johanna Mazabel
  • Jeyder Arceo-Castillo
  • José Luis Urrea-Benítez
  • Leticia Olivera-Castillo
  • Rolando Barahona-Rosales
  • Ngonidzashe Chirinda
  • Juan Ku-Vera
  • Jacobo Arango
  • Trop Anim Health Prod.2020 Jul;10.1007/s11250-020-02324-4. doi: 10.1007/s11250-020-02324-4.Epub 2020-07-09.

TOR1AIP1-associated nuclear envelopathiesの表現型をさらに拡大した2つの新規症例

Two novel cases further expand the phenotype of TOR1AIP1-associated nuclear envelopathies.
  • Ivana Lessel
  • Mei-Jan Chen
  • Sabine Lüttgen
  • Florian Arndt
  • Sigrid Fuchs
  • Stefanie Meien
  • Holger Thiele
  • Julie R Jones
  • Brandon R Shaw
  • David K Crossman
  • Peter Nürnberg
  • Bruce R Korf
  • Christian Kubisch
  • Davor Lessel
  • Hum. Genet..2020 Apr;139(4):483-498. 10.1007/s00439-019-02105-6. doi: 10.1007/s00439-019-02105-6.Epub 2020-02-13.

リトアニアの IPV ワクチン接種児を対象とした 1 価経口 2 型サビンポリオワクチン接種後の免疫原性と安全性に関する無作為化第 4 相試験

A randomized phase 4 study of immunogenicity and safety following monovalent oral type 2 Sabin polio vaccine challenge in IPV-vaccinated children in Lithuania.
  • Ananda S Bandyopadhyay
  • Chris Gast
  • Elizabeth B Brickley
  • Ricardo Rüttimann
  • Ralf Clemens
  • M Steven Oberste
  • William C Weldon
  • Margaret E Ackerman
  • Ruth I Connor
  • Wendy F Wieland-Alter
  • Peter Wright
  • Vytautas Usonis
  • J. Infect. Dis..2020 Jul;jiaa390. doi: 10.1093/infdis/jiaa390.Epub 2020-07-04.

根管形成における交渉、グライドパス、プレフレアの手順が根管形成に与える影響-用語、基本概念、および系統的なレビュー

Influence of Negotiation, Glide Path, and Preflaring Procedures on Root Canal Shaping-Terminology, Basic Concepts, and a Systematic Review.
  • Gianluca Plotino
  • Venkateshbabu Nagendrababu
  • Frederic Bukiet
  • Nicola M Grande
  • Sajesh K Veettil
  • Gustavo De-Deus
  • Hany Mohamed Aly Ahmed
  • J Endod.2020 Jun;46(6):707-729. S0099-2399(20)30076-5. doi: 10.1016/j.joen.2020.01.023.Epub 2020-04-22.

骨粗鬆症性椎体圧迫骨折(OVCF)患者の治療における片側と両側の経皮的弯曲術の比較:システマティックレビューとメタアナリシス

Comparison of unilateral versus bilateral percutaneous kyphoplasty for the treatment of patients with osteoporosis vertebral compression fracture (OVCF): a systematic review and meta-analysis.
  • Xing Cheng
  • Hou-Qing Long
  • Jing-Hui Xu
  • Yang-Liang Huang
  • Fo-Bao Li
  • Eur Spine J.2016 11;25(11):3439-3449. 10.1007/s00586-016-4395-6. doi: 10.1007/s00586-016-4395-6.Epub 2016-01-27.

5αリダクターゼ阻害剤の共投与は、処方されたグルココルチコイドの有害な代謝作用を悪化させる

Co-administration of 5α-reductase inhibitors worsens the adverse metabolic effects of prescribed glucocorticoids.
  • Nantia Othonos
  • Thomas Marjot
  • Conor Woods
  • Jonathan M Hazlehurst
  • Nikolaos Nikolaou
  • Riccardo Pofi
  • Sarah White
  • Ilaria Bonaventura
  • Craig Webster
  • Joanne Duffy
  • Thomas Cornfield
  • Ahmad Moolla
  • Andrea M Isidori
  • Leanne Hodson
  • Jeremy W Tomlinson
  • J. Clin. Endocrinol. Metab..2020 Jun;dgaa408. doi: 10.1210/clinem/dgaa408.Epub 2020-06-27.

ルネッサンスへの準備:COVID-19パンデミック時の乳がんの治療と、ユニバーサル・ヘルスケア・システム内での日常的な外科的ケアへの安全な再浮上のための計画

Preparing for the renaissance: treating breast cancer during the COVID-19 pandemic and planning for a safe re-emergence to routine surgical care within a universal health care system.
  • D Berger-Richardson
  • G Ko
  • N J Look Hong
  • Curr Oncol.2020 06;27(3):163-168. conc-27-163. doi: 10.3747/co.27.6699.Epub 2020-06-01.

ソニックヘッジホッグ/Gli経路転写標的であるNeogenin-1のダウンレギュレーションは、基底細胞癌の攻撃性と関連している

Downregulation of the Sonic Hedgehog/Gli pathway transcriptional target Neogenin-1 is associated with basal cell carcinoma aggressiveness.
  • Bárbara S Casas
  • Christelle Adolphe
  • Pablo Lois
  • Nelson Navarrete
  • Natalia Solís
  • Eva Bustamante
  • Patricio Gac
  • Patricio Cabané
  • Ivan Gallegos
  • Brandon J Wainwright
  • Verónica Palma
  • Oncotarget.2017 Oct;8(48):84006-84018. 21061. doi: 10.18632/oncotarget.21061.Epub 2017-09-19.

心筋虚血が疑われる安定した外来患者におけるフローサイトメトリーに基づく血小板反応性の性差

Sex differences in flow cytometry-based platelet reactivity in stable outpatients suspected of myocardial ischemia.
  • Farahnaz Waissi
  • Mirthe Dekker
  • Ingrid E M Bank
  • Suzanne J A Korporaal
  • Rolf T Urbanus
  • Gert J de Borst
  • Gerard Pasterkamp
  • Asbjorn M Scholtens
  • Diederick E Grobbee
  • Arend Mosterd
  • Dominique P V de Kleijn
  • Leo Timmers
  • Res Pract Thromb Haemost.2020 Jul;4(5):879-885. RTH212344. doi: 10.1002/rth2.12344.Epub 2020-05-15.

一般的なバイオマーカーから導き出された有効な死亡率リスクスコアを用いて、退院後に病院関連の静脈血栓塞栓症を医療患者の間で予測する

Predicting postdischarge hospital-associated venous thromboembolism among medical patients using a validated mortality risk score derived from common biomarkers.
  • Lindsey Snyder
  • Scott M Stevens
  • Masarret Fazili
  • Emily L Wilson
  • James F Lloyd
  • Benjamin D Horne
  • Joseph Bledsoe
  • Scott C Woller
  • Res Pract Thromb Haemost.2020 Jul;4(5):872-878. RTH212343. doi: 10.1002/rth2.12343.Epub 2020-05-20.

ヤギにおける家畜化遺伝子の起源

The origin of domestication genes in goats.
  • Zhuqing Zheng
  • Xihong Wang
  • Ming Li
  • Yunjia Li
  • Zhirui Yang
  • Xiaolong Wang
  • Xiangyu Pan
  • Mian Gong
  • Yu Zhang
  • Yingwei Guo
  • Yu Wang
  • Jing Liu
  • Yudong Cai
  • Qiuming Chen
  • Moses Okpeku
  • Licia Colli
  • Dawei Cai
  • Kun Wang
  • Shisheng Huang
  • Tad S Sonstegard
  • Ali Esmailizadeh
  • Wenguang Zhang
  • Tingting Zhang
  • Yangbin Xu
  • Naiyi Xu
  • Yi Yang
  • Jianlin Han
  • Lei Chen
  • Joséphine Lesur
  • Kevin G Daly
  • Daniel G Bradley
  • Rasmus Heller
  • Guojie Zhang
  • Wen Wang
  • Yulin Chen
  • Yu Jiang
  • Sci Adv.2020 May;6(21):eaaz5216. aaz5216. doi: 10.1126/sciadv.aaz5216.Epub 2020-05-20.

コネクトベースのモデルは大うつ病性障害の初期症状改善を予測できる

Connectome-based models can predict early symptom improvement in major depressive disorder.
  • Yumeng Ju
  • Corey Horien
  • Wentao Chen
  • Weilong Guo
  • Xiaowen Lu
  • Jinrong Sun
  • Qiangli Dong
  • Bangshan Liu
  • Jin Liu
  • Danfeng Yan
  • Mi Wang
  • Liang Zhang
  • Hua Guo
  • Futao Zhao
  • Yan Zhang
  • Xilin Shen
  • R Todd Constable
  • Lingjiang Li
  • J Affect Disord.2020 Aug;273:442-452. S0165-0327(20)30620-0. doi: 10.1016/j.jad.2020.04.028.Epub 2020-05-11.

抗ミューレリアンホルモンと卵胞数は、POSEIDON群3および4の患者における最初の完全卵巣刺激サイクルの累積治療成績を予測する能力に違いがある

Anti-Müllerian hormone and antral follicle count differ in their ability to predict cumulative treatment outcomes of the first complete ovarian stimulation cycle in patients from POSEIDON groups 3 and 4.
  • Luxin Liu
  • Canquan Zhou
  • J. Obstet. Gynaecol. Res..2020 Jul;doi: 10.1111/jog.14269.Epub 2020-07-19.

経皮的冠動脈インターベンションを受けた中国人急性冠症候群患者に対するチカグレラーとクロピドグレルの有効性評価をデータマイニングと機械学習による決定木アプローチで行った

Efficacy assessment of ticagrelor versus clopidogrel in Chinese patients with acute coronary syndrome undergoing percutaneous coronary intervention by data mining and machine-learning decision tree approaches.
  • Ying Xue
  • Ziheng Hu
  • Yankang Jing
  • Hongyi Wu
  • Xiaoye Li
  • Junmei Wang
  • Amy Seybert
  • Xiangqun Xie
  • Qianzhou Lv
  • J Clin Pharm Ther.2020 Jul;doi: 10.1111/jcpt.13172.Epub 2020-07-06.

アンキリンリピートドメイン(R635X)の病原性NFKB2変異体は可変抗体欠損症を引き起こす

Pathogenic NFKB2 variant in the ankyrin repeat domain (R635X) causes a variable antibody deficiency.
  • Paul Tuijnenburg
  • Hana Lango Allen
  • Godelieve J de Bree
  • Sinisa Savic
  • Machiel H Jansen
  • Claire Stockdale
  • Ilenia Simeoni
  • Ineke J M Ten Berge
  • Ester M M van Leeuwen
  • James E Thaventhiran
  • Taco W Kuijpers
  • Clin. Immunol..2019 06;203:23-27. S1521-6616(18)30590-4. doi: 10.1016/j.clim.2019.03.010.Epub 2019-04-03.

日常診療における関節リウマチインパクト(RAID)の使用;DAS28寛解とアンメット患者報告アウトカムの同定

Use of rheumatoid arthritis impact of disease (RAID) in routine care; identification of DAS28 remission and unmet patient-reported outcomes.
  • Jatin Mistry
  • Mohammed Sharif
  • Amy Prideaux
  • Catherine Smith
  • Malama Sumbwanyambe
  • Margaret Sibley
  • Lewis Carpenter
  • Melissa Sweeney
  • Patrick Kiely
  • Rheumatol Adv Pract.2020;4(2):rkaa013. rkaa013. doi: 10.1093/rap/rkaa013.Epub 2020-04-27.

循環性腫瘍細胞を有するHER2非増幅型早期乳癌(EORTC 90091-10093、BIG 1-12、Treat CTC)に対するトラスツズマブと観察の比較:無作為化第II相試験

Trastuzumab versus observation for HER2 nonamplified early breast cancer with circulating tumor cells (EORTC 90091-10093, BIG 1-12, Treat CTC): a randomized phase II trial.
  • M Ignatiadis
  • S Litière
  • F Rothe
  • S Riethdorf
  • C Proudhon
  • T Fehm
  • K Aalders
  • H Forstbauer
  • P A Fasching
  • E Brain
  • P Vuylsteke
  • E Guardiola
  • R Lorenz
  • K Pantel
  • K Tryfonidis
  • W Janni
  • M Piccart
  • C Sotiriou
  • B Rack
  • J-Y Pierga
  • Ann. Oncol..2018 08;29(8):1777-1783. S0923-7534(19)34129-8. doi: 10.1093/annonc/mdy211.

内視鏡支援下顎切除術。手術手技と手術縁のコントロール

Endoscopic-assisted maxillectomy: Operative technique and control of surgical margins.
  • Alberto Deganello
  • Marco Ferrari
  • Alberto Paderno
  • Mario Turri-Zanoni
  • Alberto Schreiber
  • Davide Mattavelli
  • Alperen Vural
  • Vittorio Rampinelli
  • Alberto Daniele Arosio
  • Alessandro Ioppi
  • Mario Cherubino
  • Paolo Castelnuovo
  • Piero Nicolai
  • Paolo Battaglia
  • Oral Oncol..2019 06;93:29-38. S1368-8375(19)30102-2. doi: 10.1016/j.oraloncology.2019.04.002.Epub 2019-04-11.

マングローブクラブGoniopsis cruentata(Brachyura, Grapsidae)のエラにおける(Na, K)-ATPase活性の生化学的特性とマグネシウムによるアロステリックな調節

Biochemical Characterization and Allosteric Modulation by Magnesium of (Na, K)-ATPase Activity in the Gills of the Red Mangrove Crab Goniopsis cruentata (Brachyura, Grapsidae).
  • Cintya M Moraes
  • Malson N Lucena
  • Daniela P Garçon
  • Marcelo R Pinto
  • Leonardo M Fabri
  • Rogério O Faleiros
  • Carlos F L Fontes
  • John C McNamara
  • Francisco A Leone
  • J. Membr. Biol..2020 Jun;253(3):229-245. 10.1007/s00232-020-00120-7. doi: 10.1007/s00232-020-00120-7.Epub 2020-05-22.