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日本語AIでPubMedを検索

日本語AIでPubMedを検索

PubMedの提供する医学論文データベースを日本語で検索できます。AI(Deep Learning)を活用した機械翻訳エンジンにより、精度高く日本語へ翻訳された論文をご参照いただけます。

みんなが読んでいる論文

SARS-CoV-2パパイン様プロテアーゼに対するFDA承認の抗ウイルス剤、抗生物質、駆虫剤、抗酸化剤、細胞保護剤の再利用

Repurposing of FDA-approved antivirals, antibiotics, anthelmintics, antioxidants, and cell protectives against SARS-CoV-2 papain-like protease.
  • Mahmoud Kandeel
  • Alaa H M Abdelrahman
  • Kentaro Oh-Hashi
  • Abdelazim Ibrahim
  • Katharigatta N Venugopala
  • Mohamed A Morsy
  • Mahmoud A A Ibrahim
  • J. Biomol. Struct. Dyn..2020 Jun;:1-8. doi: 10.1080/07391102.2020.1784291.Epub 2020-06-29.

霊芝水抽出物は、神経伝達、神経可塑性、レドックスホメオスタシスの維持を調節することで、低気圧性低酸素症による記憶障害を予防することができました

Ganoderma lucidum aqueous extract prevents hypobaric hypoxia induced memory deficit by modulating neurotransmission, neuroplasticity and maintaining redox homeostasis.
  • Purva Sharma
  • Rajkumar Tulsawani
  • Sci Rep.2020 Jun;10(1):8944. 10.1038/s41598-020-65812-5. doi: 10.1038/s41598-020-65812-5.Epub 2020-06-02.

オーストラリア治療成績調査:ヘロイン依存の自然史とそれに関連した死亡率、精神医学的・身体的健康、医療サービスの利用状況を調査したプロスペクティブ縦断コホートの18-20年追跡調査のプロトコール

Australian treatment outcome study: protocol for the 18-20-year follow-up of a prospective longitudinal cohort examining the natural history of heroin dependence and associated mortality, psychiatric and physical health, and health service use.
  • Christina Marel
  • Katherine Mills
  • Rachel Visontay
  • Jack Wilson
  • Shane Darke
  • Joanne Ross
  • Tim Slade
  • Paul S Haber
  • Katherine Haasnoot
  • Madeleine Keaveny
  • Chris Tremonti
  • Maree Teesson
  • BMJ Open.2020 Jul;10(7):e039226. bmjopen-2020-039226. doi: 10.1136/bmjopen-2020-039226.Epub 2020-07-12.

小児の多系統炎症性症候群(MIS-C)における全身性炎症と抗体応答のマッピング

Mapping Systemic Inflammation and Antibody Responses in Multisystem Inflammatory Syndrome in Children (MIS-C).
  • Conor Gruber
  • Roosheel Patel
  • Rebecca Trachman
  • Lauren Lepow
  • Fatima Amanat
  • Florian Krammer
  • Karen M Wilson
  • Kenan Onel
  • Daniel Geanon
  • Kevin Tuballes
  • Manishkumar Patel
  • Konstantinos Mouskas
  • Nicole Simons
  • Vanessa Barcessat
  • Diane Del Valle
  • Samantha Udondem
  • Gurpawan Kang
  • Sandeep Gangadharan
  • George Ofori-Amanfo
  • Adeeb Rahman
  • Seunghee Kim-Schulze
  • Alexander Charney
  • Sacha Gnjatic
  • Bruce Gelb
  • Miriam Merad
  • Dusan Bogunovic
  • medRxiv.2020 Jul;2020.07.04.20142752. doi: 10.1101/2020.07.04.20142752.Epub 2020-07-06.

Angiotensin-(1-7)はPdx1/Glut2の発現をアップレギュレーションすることにより、ストレプトゾトシン誘発糖尿病のラットモデルにおける膵島機能を改善した

Angiotensin-(1-7) improves Islet Function in a Rat Model of Streptozotocin-induced Diabetes Mellitus by Up-regulating the Expression of Pdx1/Glut2.
  • Jingjing Li
  • Ruifang Zhu
  • Yalin Liu
  • Jinhui Yang
  • Xiaoyan Wang
  • Lisha Geng
  • Tingting Xu
  • Junhua He
  • Endocr Metab Immune Disord Drug Targets.2020 Jul;EMIDDT-EPUB-108235. doi: 10.2174/1871530320666200717161538.Epub 2020-07-17.

急性リンパ芽球性白血病とダウン症:維持療法中の6-メルカプトプリンとメトトレキサートの代謝物

Acute lymphoblastic leukemia and down syndrome: 6-mercaptopurine and methotrexate metabolites during maintenance therapy.
  • Anna Østergaard
  • Cathrine Bohnstedt
  • Kathrine Grell
  • Matilda Degn
  • Bernward Zeller
  • Mervi Taskinen
  • Solveig Hafsteinsdottir
  • Helga Björgvinsdóttir
  • Mats Heyman
  • Peter Hoogerbrugge
  • Kjeld Schmiegelow
  • Leukemia.2020 Jul;10.1038/s41375-020-0946-2. doi: 10.1038/s41375-020-0946-2.Epub 2020-07-04.

低悪性度子宮頸部扁平上皮内病変における高リスクヒトパピローマウイルス感染症の軽度局所温熱療法による治療。3例の症例報告

Treatment of high risk human papillomavirus infection in low grade cervical squamous intraepithelial lesion with mild local thermotherapy: Three case reports.
  • Yang Yang
  • Lan Zhang
  • Ruiqun Qi
  • Wei Huo
  • Xiaodong Li
  • Xin Wu
  • Hongduo Chen
  • Xing-Hua Gao
  • Medicine (Baltimore).2020 Jul;99(27):e21005. 00005792-202007020-00098. doi: 10.1097/MD.0000000000021005.

急性リンパ芽球性白血病の小児における経口6-メルカプトプリンの錠剤および液剤の薬物動態

Pharmacokinetics of tablet and liquid formulations of oral 6-mercaptopurine in children with acute lymphoblastic leukemia.
  • Rikke Hebo Larsen
  • Lisa Lyngsie Hjalgrim
  • Kathrine Grell
  • Kim Kristensen
  • Line Gerner Pedersen
  • Emilie Damgaard Brünner
  • Bodil Als-Nielsen
  • Kjeld Schmiegelow
  • Jacob Nersting
  • Cancer Chemother. Pharmacol..2020 Jul;86(1):25-32. 10.1007/s00280-020-04097-x. doi: 10.1007/s00280-020-04097-x.Epub 2020-06-09.

HIV-1 Nefは、BECN1とその阻害剤BCL2との関連性をPRKN依存的に高めることで、オートファジー制限を打ち消す

HIV-1 Nef counteracts autophagy restriction by enhancing the association between BECN1 and its inhibitor BCL2 in a PRKN-dependent manner.
  • Sergio Castro-Gonzalez
  • Yuhang Shi
  • Marta Colomer-Lluch
  • Ying Song
  • Kaitlyn Mowery
  • Sharilyn Almodovar
  • Anju Bansal
  • Frank Kirchhoff
  • Konstantin Sparrer
  • Chengyu Liang
  • Ruth Serra-Moreno
  • Autophagy.2020 Feb;:1-25. doi: 10.1080/15548627.2020.1725401.Epub 2020-02-25.

認知的に正常な高齢者における神経変性のバイオマーカーエビデンスに関連する血漿代謝物

Plasma metabolites associated with biomarker evidence of neurodegeneration in cognitively normal older adults.
  • Pratishtha Chatterjee
  • Yeo-Jin Cheong
  • Atul Bhatnagar
  • Kathryn Goozee
  • Yunqi Wu
  • Matthew McKay
  • Ian J Martins
  • Wei L F Lim
  • Steve Pedrini
  • Michelle Tegg
  • Victor L Villemagne
  • Prita R Asih
  • Preeti Dave
  • Tejal M Shah
  • Cintia B Dias
  • Stephanie J Fuller
  • Heidi Hillebrandt
  • Sunil Gupta
  • Eugene Hone
  • Kevin Taddei
  • Henrik Zetterberg
  • Kaj Blennow
  • Hamid R Sohrabi
  • Ralph N Martins
  • J. Neurochem..2020 Jul;doi: 10.1111/jnc.15128.Epub 2020-07-17.

酸化ストレスのマーカーであるプロテインカルボニルの血清レベルは,血液透析患者の過湿,サルコペニア,死亡率と関連していた.

Serum levels of protein carbonyl, a marker of oxidative stress, are associated with overhydration, sarcopenia and mortality in hemodialysis patients.
  • Young Rim Song
  • Jwa-Kyung Kim
  • Hyung-Seok Lee
  • Sung Gyun Kim
  • Eun-Kyoung Choi
  • BMC Nephrol.2020 Jul;21(1):281. 10.1186/s12882-020-01937-z. doi: 10.1186/s12882-020-01937-z.Epub 2020-07-16.

Burkardら、"Pigs Lacking the Scavenger Receptor Cysteine-Rich Domain 5 of CD163 Are Resistant to Porcine Reproductive and Respiratory Syndrome Virus 1 Infection"のErratum

Erratum for Burkard et al., "Pigs Lacking the Scavenger Receptor Cysteine-Rich Domain 5 of CD163 Are Resistant to Porcine Reproductive and Respiratory Syndrome Virus 1 Infection".
  • Christine Burkard
  • Tanja Opriessnig
  • Alan J Mileham
  • Tomasz Stadejek
  • Tahar Ait-Ali
  • Simon G Lillico
  • C Bruce A Whitelaw
  • Alan L Archibald
  • J. Virol..2020 Jul;94(15). e00951-20. doi: 10.1128/JVI.00951-20.Epub 2020-07-16.

肺腺癌患者における上皮成長因子受容体の突然変異の状態と予後を予測するためのF-フルオロデオキシグルコース陽電子放射断層撮影/コンピュータ断層撮影に基づく放射線学的特徴

F-fluorodeoxyglucose positron emission tomography/computed tomography-based radiomic features for prediction of epidermal growth factor receptor mutation status and prognosis in patients with lung adenocarcinoma.
  • Bin Yang
  • Heng-Shan Ji
  • Chang-Sheng Zhou
  • Hao Dong
  • Lu Ma
  • Ying-Qian Ge
  • Chao-Hui Zhu
  • Jia-He Tian
  • Long-Jiang Zhang
  • Hong Zhu
  • Guang-Ming Lu
  • Transl Lung Cancer Res.2020 Jun;9(3):563-574. tlcr-09-03-563. doi: 10.21037/tlcr-19-592.

脳ポジトロン断層撮影で18F-fludeoxyglucose uptakeが低い原発性中枢神経系リンパ腫の臨床病理学的特徴.

Clinicopathological characteristics of primary central nervous system lymphoma with low 18F-fludeoxyglucose uptake on brain positron emission tomography.
  • Hye Ok Kim
  • Jae Seung Kim
  • Seon-Ok Kim
  • Sun Young Chae
  • Seung Jun Oh
  • Minjung Seo
  • Suk Hyun Lee
  • Jungsu S Oh
  • Jin-Sook Ryu
  • Joo-Ryung Huh
  • Jeong Hoon Kim
  • Medicine (Baltimore).2020 May;99(20):e20140. 00005792-202005150-00044. doi: 10.1097/MD.0000000000020140.

ヘルスケア関連 COVID-19 の症例を調査するための SARS-CoV-2 シーケンシングの迅速な実施:プロスペクティブなゲノムサーベイランス研究

Rapid implementation of SARS-CoV-2 sequencing to investigate cases of health-care associated COVID-19: a prospective genomic surveillance study.
  • Luke W Meredith
  • William L Hamilton
  • Ben Warne
  • Charlotte J Houldcroft
  • Myra Hosmillo
  • Aminu S Jahun
  • Martin D Curran
  • Surendra Parmar
  • Laura G Caller
  • Sarah L Caddy
  • Fahad A Khokhar
  • Anna Yakovleva
  • Grant Hall
  • Theresa Feltwell
  • Sally Forrest
  • Sushmita Sridhar
  • Michael P Weekes
  • Stephen Baker
  • Nicholas Brown
  • Elinor Moore
  • Ashley Popay
  • Iain Roddick
  • Mark Reacher
  • Theodore Gouliouris
  • Sharon J Peacock
  • Gordon Dougan
  • M Estée Török
  • Ian Goodfellow
  • Lancet Infect Dis.2020 Jul;S1473-3099(20)30562-4. doi: 10.1016/S1473-3099(20)30562-4.Epub 2020-07-14.

Βeta-interferon I-a のバイオシミラー製剤の有効性と安全性の比較研究。イランにおける無作為化対照臨床試験

A Comparison Study of Efficacy and Safety of a Biosimilar Form of Intramuscular Βeta-interferon I-a Versus the Reference Product: A Randomized Controlled Clinical Trial in Iran.
  • Seyed Massood Nabavi
  • Roya Abolfazli
  • Ali Etemadrezaei
  • Hamed Hosseini
  • Nahid Moradi
  • Sanaz Shahriari
  • Baharak Mehdipour
  • Babak Shekarchi
  • Akbar Soltanzadeh
  • Iran J Pharm Res.2019;18(3):1632-1638. doi: 10.22037/ijpr.2019.14503.12441.

ステビア(ベルトーニ)、アムロジピン、ロサルタン、バルサルタンの水消費量、血糖値、心臓組織への影響に関するデータセット

Dataset concerning effects of stevia ( bertoni), amlodipine, losartan, and valsartan on water consumption, blood glucose and heart tissue in gentamycin-induced nephrotoxicity in the rat model.
  • Farhana Rizwan
  • Saquiba Yesmine
  • Ishtiaque Ahmed Chowdhury
  • Sultana Gulshana Banu
  • Tapan Kumar Chatterjee
  • Data Brief.2020 Aug;31:105965. S2352-3409(20)30859-3. doi: 10.1016/j.dib.2020.105965.Epub 2020-07-03.

パキスタンの32家族における常染色体劣性原発性小頭症の原因となっているASPM、WDR62、CDK5RAP2、STIL、CENPJ、CEP135の病原性変異体の最新情報

An update of pathogenic variants in ASPM, WDR62, CDK5RAP2, STIL, CENPJ, and CEP135 underlying autosomal recessive primary microcephaly in 32 consanguineous families from Pakistan.
  • Sajida Rasool
  • Jamshaid Mahmood Baig
  • Abubakar Moawia
  • Ilyas Ahmad
  • Maria Iqbal
  • Syeda Seema Waseem
  • Maria Asif
  • Uzma Abdullah
  • Ehtisham Ul Haq Makhdoom
  • Emrah Kaygusuz
  • Muhammad Zakaria
  • Shafaq Ramzan
  • Saif Ul Haque
  • Asif Mir
  • Iram Anjum
  • Mehak Fiaz
  • Zafar Ali
  • Muhammad Tariq
  • Neelam Saba
  • Wajid Hussain
  • Birgit Budde
  • Saba Irshad
  • Angelika Anna Noegel
  • Stefan Höning
  • Shahid Mahmood Baig
  • Peter Nürnberg
  • Muhammad Sajid Hussain
  • Mol Genet Genomic Med.2020 Jul;:e1408. doi: 10.1002/mgg3.1408.Epub 2020-07-17.