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日本語AIでPubMedを検索

日本語AIでPubMedを検索

PubMedの提供する医学論文データベースを日本語で検索できます。AI(Deep Learning)を活用した機械翻訳エンジンにより、精度高く日本語へ翻訳された論文をご参照いただけます。

みんなが読んでいる論文

医薬品の連続製造におけるプロセスオペレーション管理のための条件ベースのメンテナンスフレームワークの設計

Design of Condition-based Maintenance Framework for Process Operations Management in Pharmaceutical Continuous Manufacturing.
  • Sudarshan Ganesh
  • Qinglin Su
  • Le Bao Dan Vo
  • Nolan Pepka
  • Ben Rentz
  • Lucas Vann
  • Nima Yazdanpanah
  • Thomas O'Connor
  • Zoltan Nagy
  • Gintaras Reklaitis
  • Int J Pharm.2020 Jul;:119621. S0378-5173(20)30605-0. doi: 10.1016/j.ijpharm.2020.119621.Epub 2020-07-11.

製造販売承認保有者が後援する患者支援プログラムからの有害事象報告が、ファーマコビジランスにおけるシグナル検出のパフォーマンスに与える影響

Impact of adverse event reports from marketing authorization holder-sponsored patient support programs on the performance of signal detection in pharmacovigilance.
  • Inyoung Lee
  • Todd A Lee
  • Stephanie Y Crawford
  • Ryan D Kilpatrick
  • Gregory S Calip
  • Jeremy D Jokinen
  • Expert Opin Drug Saf.2020 Jul;doi: 10.1080/14740338.2020.1792883.Epub 2020-07-14.

院内肺炎におけるカルバペネム耐性感染の危険因子、分子疫学、および転帰。2015年から2017年の間に中国東部で行われたマッチドケースコントロール研究

Risk Factors, Molecular Epidemiology, and Outcomes of Carbapenem-Resistant Infection for Hospital-Acquired Pneumonia: A Matched Case-Control Study in Eastern China During 2015-2017.
  • Yan Zuo
  • Dongmei Zhao
  • Guobin Song
  • Jiabin Li
  • Yuanhong Xu
  • Zhongxin Wang
  • Microb. Drug Resist..2020 Jul;doi: 10.1089/mdr.2020.0162.Epub 2020-07-02.

てんかん電子患者ポータルの開発。COVID-19後の世界における患者のエンパワーメントと遠隔地の臨床医と患者の相互作用の両方を促進する

The Development of an Epilepsy Electronic Patient Portal: Facilitating both patient empowerment and remote clinician-patient interaction in a post COVID-19 world.
  • Kevin Power
  • Zita McCrea
  • Maire White
  • Annette Breen
  • Brendan Dunleavy
  • Sean O'Donoghue
  • Tim Jacquemard
  • Veronica Lambert
  • Hany El-Naggar
  • Norman Delanty
  • Colin Doherty
  • Mary Fitzsimons
  • Epilepsia.2020 Jul;doi: 10.1111/epi.16627.Epub 2020-07-15.

抗生物質スチュワードシップの推進における民間セクターの役割。世界最高医療責任者ネットワークからの提言

The Role of the Private Sector in Advancing Antimicrobial Stewardship: Recommendations from the Global Chief Medical Officers' Network.
  • Elizabeth D Hermsen
  • Richard Jenkins
  • Ivo Vlaev
  • Steve Iley
  • Thirumalai Rajgopal
  • Jonathan Mark Sackier
  • Pietie Loubser
  • Nico Pronk
  • Elizabeth Wilkinson
  • Yat Chow
  • Cathryn Gunther
  • Popul Health Manag.2020 Jul;doi: 10.1089/pop.2020.0027.Epub 2020-07-13.

セイウチ(Sander vitreus)のGT-seqパネルは、非モデル生物におけるアンプリコンパネルの効率的な開発と実装のための重要な洞察を提供しています

A GT-seq panel for walleye (Sander vitreus) provides important insights for efficient development and implementation of amplicon panels in non-model organisms.
  • Matthew L Bootsma
  • Kristen M Gruenthal
  • Garrett J McKinney
  • Levi Simmons
  • Loren Miller
  • Greg G Sass
  • Wesley A Larson
  • Mol Ecol Resour.2020 Jul;doi: 10.1111/1755-0998.13226.Epub 2020-07-15.

乳がん患者における公的医療保険とがん特異的死亡リスク。中国におけるプロスペクティブ・コホート研究

Public health insurance and cancer-specific mortality risk among patients with breast cancer: A prospective cohort study in China.
  • Yuxin Xie
  • Unnur A Valdimarsdóttir
  • Chengshi Wang
  • XiaoRong Zhong
  • Qiheng Gou
  • Hong Zheng
  • Ling Deng
  • Ping He
  • Kejia Hu
  • Katja Fall
  • Fang Fang
  • Rulla M Tamimi
  • Ting Luo
  • Donghao Lu
  • Int. J. Cancer.2020 Jul;doi: 10.1002/ijc.33183.Epub 2020-07-04.

循環器内科医による診療を受けた患者と非循環器内科医による診療を受けた患者との間の心臓病の入院転帰。プロペンシティスコアをマッチさせた研究

Hospitalization outcome of heart diseases between patients who received medical care by cardiologists and non-cardiologist physicians: A propensity-score matched study.
  • Yu-Ming Wu
  • Chih-Chung Liu
  • Chun-Chieh Yeh
  • Li-Chin Sung
  • Chao-Shun Lin
  • Yih-Giun Cherng
  • Ta-Liang Chen
  • Chien-Chang Liao
  • PLoS ONE.2020;15(7):e0235207. PONE-D-19-20841. doi: 10.1371/journal.pone.0235207.Epub 2020-07-06.

生殖型のHOXB13変異p.G84Eおよびp.R217Cは乳がんリスクの増加をもたらさない

Germline HOXB13 mutations p.G84E and p.R217C do not confer an increased breast cancer risk.
  • Jingjing Liu
  • Wendy J C Prager-van der Smissen
  • J Margriet Collée
  • Manjeet K Bolla
  • Qin Wang
  • Kyriaki Michailidou
  • Joe Dennis
  • Thomas U Ahearn
  • Kristiina Aittomäki
  • Christine B Ambrosone
  • Irene L Andrulis
  • Hoda Anton-Culver
  • Natalia N Antonenkova
  • Volker Arndt
  • Norbert Arnold
  • Kristan J Aronson
  • Annelie Augustinsson
  • Päivi Auvinen
  • Heiko Becher
  • Matthias W Beckmann
  • Sabine Behrens
  • Marina Bermisheva
  • Leslie Bernstein
  • Natalia V Bogdanova
  • Nadja Bogdanova-Markov
  • Stig E Bojesen
  • Hiltrud Brauch
  • Hermann Brenner
  • Ignacio Briceno
  • Sara Y Brucker
  • Thomas Brüning
  • Barbara Burwinkel
  • Qiuyin Cai
  • Hui Cai
  • Daniele Campa
  • Federico Canzian
  • Jose E Castelao
  • Jenny Chang-Claude
  • Stephen J Chanock
  • Ji-Yeob Choi
  • Melissa Christiaens
  • Christine L Clarke
  • Fergus J Couch
  • Kamila Czene
  • Mary B Daly
  • Peter Devilee
  • Isabel Dos-Santos-Silva
  • Miriam Dwek
  • Diana M Eccles
  • A Heather Eliassen
  • Peter A Fasching
  • Jonine Figueroa
  • Henrik Flyger
  • Lin Fritschi
  • Manuela Gago-Dominguez
  • Susan M Gapstur
  • Montserrat García-Closas
  • José A García-Sáenz
  • Mia M Gaudet
  • Graham G Giles
  • Mark S Goldberg
  • David E Goldgar
  • Pascal Guénel
  • Christopher A Haiman
  • Niclas Håkansson
  • Per Hall
  • Patricia A Harrington
  • Steven N Hart
  • Mikael Hartman
  • Peter Hillemanns
  • John L Hopper
  • Ming-Feng Hou
  • David J Hunter
  • Dezheng Huo
  • Hidemi Ito
  • Motoki Iwasaki
  • Milena Jakimovska
  • Anna Jakubowska
  • Esther M John
  • Rudolf Kaaks
  • Daehee Kang
  • Renske Keeman
  • Elza Khusnutdinova
  • Sung-Won Kim
  • Peter Kraft
  • Vessela N Kristensen
  • Allison W Kurian
  • Loic Le Marchand
  • Jingmei Li
  • Annika Lindblom
  • Artitaya Lophatananon
  • Robert N Luben
  • Jan Lubiński
  • Arto Mannermaa
  • Mehdi Manoochehri
  • Siranoush Manoukian
  • Sara Margolin
  • Shivaani Mariapun
  • Keitaro Matsuo
  • Tabea Maurer
  • Dimitrios Mavroudis
  • Alfons Meindl
  • Usha Menon
  • Roger L Milne
  • Kenneth Muir
  • Anna Marie Mulligan
  • Susan L Neuhausen
  • Heli Nevanlinna
  • Kenneth Offit
  • Olufunmilayo I Olopade
  • Janet E Olson
  • Håkan Olsson
  • Nick Orr
  • Sue K Park
  • Paolo Peterlongo
  • Julian Peto
  • Dijana Plaseska-Karanfilska
  • Nadege Presneau
  • Brigitte Rack
  • Rohini Rau-Murthy
  • Gad Rennert
  • Hedy S Rennert
  • Valerie Rhenius
  • Atocha Romero
  • Matthias Ruebner
  • Emmanouil Saloustros
  • Rita K Schmutzler
  • Andreas Schneeweiss
  • Christopher Scott
  • Mitul Shah
  • Chen-Yang Shen
  • Xiao-Ou Shu
  • Jacques Simard
  • Christof Sohn
  • Melissa C Southey
  • John J Spinelli
  • Rulla M Tamimi
  • William J Tapper
  • Soo H Teo
  • Mary Beth Terry
  • Diana Torres
  • Thérèse Truong
  • Michael Untch
  • Celine M Vachon
  • Christi J van Asperen
  • Alicja Wolk
  • Taiki Yamaji
  • Wei Zheng
  • Argyrios Ziogas
  • Elad Ziv
  • Gabriela Torres-Mejía
  • Thilo Dörk
  • Anthony J Swerdlow
  • Ute Hamann
  • Marjanka K Schmidt
  • Alison M Dunning
  • Paul D P Pharoah
  • Douglas F Easton
  • Maartje J Hooning
  • John W M Martens
  • Antoinette Hollestelle
  • Sci Rep.2020 Jun;10(1):9688. 10.1038/s41598-020-65665-y. doi: 10.1038/s41598-020-65665-y.Epub 2020-06-16.

循環器内科で使用されるジェネリック医薬品は、ブランド品と同等の効果と安全性があるか?システマティックレビューとメタアナリシス

Are Generic Drugs Used in Cardiology as Effective and Safe as their Brand-name Counterparts? A Systematic Review and Meta-analysis.
  • Jacinthe Leclerc
  • Magalie Thibault
  • Jennifer Midiani Gonella
  • Claudia Beaudoin
  • John Sampalis
  • Drugs.2020 May;80(7):697-710. 10.1007/s40265-020-01296-x. doi: 10.1007/s40265-020-01296-x.

生存関連ドナーからのデノボ腎移植患者におけるタクロリムスの実際の生物学的同等性。観察研究

Real-life Bioequivalence of Tacrolimus in Patients With Living-Related Donor De Novo Renal Transplantation: An Observational Study.
  • Priyanka Naithani
  • Sumit Dey
  • Savita Verma Attri
  • Amol Patil
  • Ajay Patial
  • Sheetal Singh
  • Ritika Panwar
  • S P Sivakumar
  • Sarbpreet Singh
  • Deepesh Benjamin Kenwar
  • Smita Pattanaik
  • Ashish Sharma
  • Transplant. Proc..2020 May;S0041-1345(19)31738-5. doi: 10.1016/j.transproceed.2020.03.017.Epub 2020-05-21.

乾燥血液スポット(DBS)カードを用いたインカード再分析(ISR)を行うための新しい方法論 - ダロルトアミドとフィルゴチニブを用いた実験データ

Novel methodology to perform incurred sample reanalysis (ISR) on dried blood spot (DBS) cards - Experimental data using darolutamide and filgotinib.
  • Vinay Kiran
  • Abhishek Dixit
  • Bhavesh Babulal Gabani
  • Nuggehally R Srinivas
  • Ramesh Mullangi
  • Biomed. Chromatogr..2020 Jul;:e4938. doi: 10.1002/bmc.4938.Epub 2020-07-02.

オートイデム規制を背景とした家庭医・薬剤師間での製品特性の要約(SmPC)の使用。探索的クロスセクション調査の結果

[Use of summaries of product characteristics (SmPC) among family doctors and pharmacists in the context of the aut-idem regulation: Results of an exploratory cross-sectional survey].
  • Maximilian Gahr
  • Roland W Freudenmann
  • Bernhard J Connemann
  • Carlos Schönfeldt-Lecuona
  • Rainer Muche
  • Christoph Hiemke
  • Yannick M Sillmann
  • Z Evid Fortbild Qual Gesundhwes.2020 Apr;150-152:45-53. S1865-9217(20)30040-4. doi: 10.1016/j.zefq.2020.03.009.Epub 2020-05-19.

パーキンソン病における扁桃体-アクンベンス-弾道経路の異常な繊維コヒーレンスは、組織化されたNigrostriatal-Nigropallidal経路と関連している

Aberrant Fiber Coherence of Amygdala-Accumbens-Pallidum Pathway Is Associated With Disorganized Nigrostriatal-Nigropallidal Pathway in Parkinson's Disease.
  • Tao Guo
  • Jingjing Wu
  • Cheng Zhou
  • Xiaojun Guan
  • Ting Gao
  • Xueqin Bai
  • Zhe Song
  • Min Xuan
  • Quanquan Gu
  • Peiyu Huang
  • Baorong Zhang
  • Jiali Pu
  • Xiaojun Xu
  • Duan Xu
  • Minming Zhang
  • J Magn Reson Imaging.2020 Jul;:e27273. doi: 10.1002/jmri.27273.Epub 2020-07-13.

仙骨前空間への針の進入による直腸穿刺のリスク。直腸と仙骨の距離、仙骨の厚みを測定することの重要性

Risk of rectal puncture due to needle entry into the presacral space: Importance of measuring the distance between the rectum and sacrococcyx, and the thickness of the sacrococcyx.
  • Young Suk Kwon
  • Narea Lee
  • Ho Seok Lee
  • Eun Ji Youn
  • Soo Kyung Lee
  • Youngmi Kim
  • Jae Jun Lee
  • Medicine (Baltimore).2020 Jul;99(28):e20935. 00005792-202007100-00041. doi: 10.1097/MD.0000000000020935.

健康な男性ボランティアにおけるカプマチニブ(INC280)の吸収・分布・代謝・排泄(ADME)と主要代謝物の体外でのアルデヒド酸化酵素フェノタイピング

Absorption, Distribution, Metabolism, and Excretion (ADME) of Capmatinib (INC280) in Healthy Male Volunteers and In Vitro Aldehyde Oxidase Phenotyping of the Major Metabolite.
  • Ulrike Glaenzel
  • Yi Jin
  • Regine Hansen
  • Kirsten Schroer
  • Gholamreza Rahmanzadeh
  • Ulrike Pfaar
  • Jan Jaap van Lier
  • Hubert Borell
  • Axel Meissner
  • Gian Camenisch
  • Sylvia Zhao
  • Drug Metab. Dispos..2020 Jul;dmd.119.090324. doi: 10.1124/dmd.119.090324.Epub 2020-07-14.

CRL1505のペプチドグリカンによって誘導される呼吸器同期ウイルスおよび肺炎球菌超感染症に対する改善された保護における肺胞マクロファージの役割

The Role of Alveolar Macrophages in the Improved Protection against Respiratory Syncytial Virus and Pneumococcal Superinfection Induced by the Peptidoglycan of CRL1505.
  • Patricia Clua
  • Mikado Tomokiyo
  • Fernanda Raya Tonetti
  • Md Aminul Islam
  • Valeria García Castillo
  • Guillermo Marcial
  • Susana Salva
  • Susana Alvarez
  • Hideki Takahashi
  • Shoichiro Kurata
  • Haruki Kitazawa
  • Julio Villena
  • Cells.2020 Jul;9(7). E1653. doi: 10.3390/cells9071653.Epub 2020-07-09.

再発性クロストリジオイデスびまん性大腸炎に対する糞便微生物移植における、少量の冷凍糞便と比較して、高容量の新鮮な糞便の優越性

Superiority of Higher-Volume Fresh Feces Compared to Lower-Volume Frozen Feces in Fecal Microbiota Transplantation for Recurrent Clostridioides Difficile Colitis.
  • Amol Agarwal
  • Anurag Maheshwari
  • Sandeep Verma
  • Denise Arrup
  • Laila Phillips
  • Rakesh Vinayek
  • Padmanabhan Nair
  • Matilda Hagan
  • Sudhir Dutta
  • Dig. Dis. Sci..2020 Jul;10.1007/s10620-020-06459-0. doi: 10.1007/s10620-020-06459-0.Epub 2020-07-11.

アルゼンチンにおけるCOVID-19に対する免疫力の高い馬血清療法の開発

Development of a hyperimmune equine serum therapy for COVID-19 in Argentina.
  • Vanesa Zylberman
  • Santiago Sanguineti
  • Andrea V Pontoriero
  • Sandra V Higa
  • María L Cerutti
  • Susana M Morrone Seijo
  • Romina Pardo
  • Luciana Muñoz
  • María E Acuña Intrieri
  • Vanina A Alzogaray
  • Martín M Avaro
  • Estefanía Benedetti
  • Paula M Berguer
  • Laura Bocanera
  • Lucas Bukata
  • Marina S Bustelo
  • Ana M Campos
  • Mariana Colonna
  • Elisa Correa
  • Lucía Cragnaz
  • María E Dattero
  • María Dellafiore
  • Sabrina Foscaldi
  • Joaquín V González
  • Luciano L Guerra
  • Sebastián Klinke
  • María S Labanda
  • Constanza Lauché
  • Juan C López
  • Anabela M Martínez
  • Lisandro H Otero
  • Elías H Peyric
  • Pablo F Ponziani
  • Romina Ramondino
  • Jimena Rinaldi
  • Santiago Rodríguez
  • Javier E Russo
  • Mara L Russo
  • Soledad L Saavedra
  • Mauricio Seigelchifer
  • Santiago Sosa
  • Claudio Vilariño
  • Patricia López Biscayart
  • Esteban Corley
  • Linus Spatz
  • Elsa G Baumeister
  • Fernando A Goldbaum
  • Medicina (B Aires).2020;80 Suppl 3:1-6.

SGLT2(ナトリウム-グルコースコトランスポーター2)阻害薬とGLP-1(グルカゴン-ライクペプチド-1)受容体アゴニストはどのように心血管系の転帰を減少させるか?終了した試験および現在進行中のメカニズム論的試験

How Do SGLT2 (Sodium-Glucose Cotransporter 2) Inhibitors and GLP-1 (Glucagon-Like Peptide-1) Receptor Agonists Reduce Cardiovascular Outcomes?: Completed and Ongoing Mechanistic Trials.
  • Matthew M Y Lee
  • Mark C Petrie
  • John J V McMurray
  • Naveed Sattar
  • Arterioscler. Thromb. Vasc. Biol..2020 03;40(3):506-522. doi: 10.1161/ATVBAHA.119.311904.Epub 2020-01-30.

イヌ軟部組織肉腫に対するワクチンウイルス媒介腫瘍治療における"トロイの木馬"としてのイヌ脂肪由来間葉系幹細胞(cAdMSCs)

Canine Adipose-Derived Mesenchymal Stem Cells (cAdMSCs) as a "Trojan Horse" in Vaccinia Virus Mediated Oncolytic Therapy against Canine Soft Tissue Sarcomas.
  • Ivan Petrov
  • Ivaylo Gentschev
  • Anna Vyalkova
  • Mohamed I Elashry
  • Michele C Klymiuk
  • Stefan Arnhold
  • Aladar A Szalay
  • Viruses.2020 Jul;12(7). E750. doi: 10.3390/v12070750.Epub 2020-07-12.

切歯の側方脱臼-新しいコーンビームCTソフトとリポジショニングガイドラインを用いた症例報告

Lateral Luxation of Incisor - A Case Report of Using a New Cone-Beam Computed Tomography Software and Reposition Guideline.
  • Priscilla Barbosa Ferreira Soares
  • Andomar Bruno Fernandes Vilela
  • Camilla Christian Gomes Moura
  • Carlos Estrela
  • Mike R Bueno
  • Carlos José Soares
  • Braz Dent J.2020 Jun;31(3):337-343. S0103-64402020000300337. doi: 10.1590/0103-6440202003069.Epub 2020-07-13.

エチオピア、メテケル地域の家畜に対するトリパノソーマ症の影響を最小限に抑えるために、地域に根ざしたツェツェツェバエの防除が行われている

Community-based tsetse fly control minimizes the effect of trypanosomosis on livestock in Metekel zone, Ethiopia.
  • Gebrerufael Girmay
  • Bezna Arega
  • Dirk Berkvens
  • Solomon Z Altaye
  • Gadisa Muleta
  • Trop Anim Health Prod.2018 Mar;50(3):621-627. 10.1007/s11250-017-1478-2. doi: 10.1007/s11250-017-1478-2.Epub 2017-11-29.

根治的前立腺摘除術後の生化学的障害に対する高線量放射線療法による長期対短期アンドロゲン遮断療法:無作為化比較試験

Long- versus short-term androgen deprivation therapy with high-dose radiotherapy for biochemical failure after radical prostatectomy: a randomized controlled trial.
  • Charlien Berghen
  • Steven Joniau
  • Annouschka Laenen
  • Gaetan Devos
  • Kato Rans
  • Karolien Goffin
  • Karin Haustermans
  • Gert De Meerleer
  • Future Oncol.2020 Jul;doi: 10.2217/fon-2020-0390.Epub 2020-07-15.

再発膠芽腫患者に対するブパルリシブとカルボプラチンまたはロムスチンの併用:第Ib/II相、非盲検、多施設、無作為化試験

Buparlisib plus carboplatin or lomustine in patients with recurrent glioblastoma: a phase Ib/II, open-label, multicentre, randomised study.
  • Mark Rosenthal
  • Paul M Clement
  • Mario Campone
  • Miguel J Gil-Gil
  • John DeGroot
  • Olivier Chinot
  • Ahmed Idbaih
  • Hui Gan
  • Jeffrey Raizer
  • Patrick Yung Wen
  • Estela Pineda
  • Valerie Donnet
  • David Mills
  • Mona El-Hashimy
  • Warren Mason
  • ESMO Open.2020 Jul;5(4). e000672. doi: 10.1136/esmoopen-2020-000672.

サイクリン依存性キナーゼにおける再発性ゲノム変化の系統的解析から、がん治療のための潜在的な治療戦略が明らかにされる

Systematic Characterization of Recurrent Genomic Alterations in Cyclin-Dependent Kinases Reveals Potential Therapeutic Strategies for Cancer Treatment.
  • Weiwei Shan
  • Jiao Yuan
  • Zhongyi Hu
  • Junjie Jiang
  • Yueying Wang
  • Nicki Loo
  • Lingling Fan
  • Zhaoqing Tang
  • Tianli Zhang
  • Mu Xu
  • Yutian Pan
  • Jiaqi Lu
  • Meixiao Long
  • Janos L Tanyi
  • Kathleen T Montone
  • Yi Fan
  • Xiaowen Hu
  • Youyou Zhang
  • Lin Zhang
  • Cell Rep.2020 Jul;32(2):107884. S2211-1247(20)30865-2. doi: 10.1016/j.celrep.2020.107884.

肝細胞癌におけるPUMAを介したアポトーシスを介したミリプラチンと放射線の相乗的な抗腫瘍活性

Synergistic anti-tumor activity of miriplatin and radiation through PUMA-mediated apoptosis in hepatocellular carcinoma.
  • Hironori Tanaka
  • Koichi Okamoto
  • Yasushi Sato
  • Takahiro Tanaka
  • Tetsu Tomonari
  • Fumika Nakamura
  • Yasuteru Fujino
  • Yasuhiro Mitsui
  • Hiroshi Miyamoto
  • Naoki Muguruma
  • Akinori Morita
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