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日本語AIでPubMedを検索

日本語AIでPubMedを検索

PubMedの提供する医学論文データベースを日本語で検索できます。AI(Deep Learning)を活用した機械翻訳エンジンにより、精度高く日本語へ翻訳された論文をご参照いただけます。

みんなが読んでいる論文

血糖調節のためのインテリジェントなグルコース応答性スイッチを備えたインスリンの経口デリバリーが求められている

Oral delivery of insulin with intelligent glucose-responsive switch for blood glucose regulation.
  • Xia Zhou
  • Hongwei Wu
  • Ruimin Long
  • Shibin Wang
  • Haiwang Huang
  • Yanhua Xia
  • Pei Wang
  • Yifeng Lei
  • Yuanyuan Cai
  • Duanhua Cai
  • Yuangang Liu
  • J Nanobiotechnology.2020 Jul;18(1):96. 10.1186/s12951-020-00652-z. doi: 10.1186/s12951-020-00652-z.Epub 2020-07-14.

スプリングカム機構を用いた背屈抵抗を有する足関節装具は、脳卒中片麻痺患者の歩行時の旋回相における膝の屈曲性を向上させる

Ankle-foot orthosis with dorsiflexion resistance using spring-cam mechanism increases knee flexion in the swing phase during walking in stroke patients with hemiplegia.
  • Yusuke Sekiguchi
  • Dai Owaki
  • Keita Honda
  • Kenichiro Fukushi
  • Noriyoshi Hiroi
  • Takeo Nozaki
  • Shin-Ichi Izumi
  • Gait Posture.2020 Jul;81:27-32. S0966-6362(20)30230-7. doi: 10.1016/j.gaitpost.2020.06.029.Epub 2020-07-02.

20S-protopanaxatriolは、FXRを介した炎症性シグナル伝達カスケードが関与している可能性がある肝線維症を改善します

20S-protopanaxatriol ameliorates hepatic fibrosis potentially involving of FXR-mediated inflammatory signaling cascades.
  • Jian Song
  • Zhen-Yu Cui
  • Li-Hua Lian
  • Xin Han
  • Li-Shuang Hou
  • Ge Wang
  • Lu Gao
  • Yue Zhu
  • Yu-Chen Jiang
  • Jia-Yi Dou
  • Zhong-He Hu
  • Yuqing Zhao
  • Ji-Xing Nan
  • Yan-Ling Wu
  • J. Agric. Food Chem..2020 Jul;doi: 10.1021/acs.jafc.0c01978.Epub 2020-07-14.

燃料および塗料に暴露された労働者におけるDNA損傷と炎症反応

DNA damage and inflammatory response in workers exposed to fuels and paints.
  • Evelyne da Silva Brum
  • Lílian Marquezini da Silva
  • Taiane Piccini Teixeira
  • Laís da Rosa Moreira
  • Helena Kober
  • Marinês Calegari Lavall
  • José Édson Paz da Silva
  • Mariana Piana
  • Luana Suéling Lenz
  • Ivana Beatrice Mânica da Cruz
  • Thiago Duarte
  • Marta Maria Medeiros Frescura Duarte
  • Ricardo Brandão
  • Arch Environ Occup Health.2020 Jul;:1-11. doi: 10.1080/19338244.2020.1783502.Epub 2020-07-02.

骨質、ドリリングプロトコル、インプラント径/長さが一次安定性に及ぼす影響。挿入トルクと共振周波数解析の体外比較研究

Influence of Bone Quality, Drilling Protocol, Implant Diameter/Length on Primary Stability: An In Vitro Comparative Study on Insertion Torque and Resonance Frequency Analysis.
  • Davide Farronato
  • Mattia Manfredini
  • Michele Stocchero
  • Mattia Caccia
  • Lorenzo Azzi
  • Marco Farronato
  • J Oral Implantol.2020 Jun;46(3):182-189. 427213. doi: 10.1563/aaid-joi-D-19-00145.

次世代シークエンシングにより、肺大細胞神経内分泌癌における新規のクリゾチニブ感受性PLB1-ALK再配列が同定された

Next-Generation Sequencing Identified a Novel Crizotinib-Sensitive PLB1-ALK Rearrangement in Lung Large-Cell Neuroendocrine Carcinoma.
  • Shuai Wang
  • Xuan Wu
  • Jiuzhou Zhao
  • Haiyang Chen
  • Zhe Zhang
  • Mingyue Wang
  • Cong Xu
  • Yongsen Wang
  • Lili Wang
  • Zhen He
  • Qiming Wang
  • Clin Lung Cancer.2020 Jun;S1525-7304(20)30166-2. doi: 10.1016/j.cllc.2020.05.026.Epub 2020-06-02.

韓国における破傷風トキソイド、還元型ジフテリアトキソイド、無菌性百日咳(Tdap)ワクチンの安全性に関する6年間の前向き、観察的、多施設の市販後調査

A 6-year Prospective, Observational, Multi-Center Post-Marketing Surveillance of the Safety of Tetanus Toxoid, Reduced Diphtheria Toxoid, and Acellular Pertussis (Tdap) Vaccine in Korea.
  • Hee-Jin Park
  • Sung Jin Kim
  • Rok Song
  • Jing Chen
  • Joon-Hyung Kim
  • Raghavendra Devadiga
  • Hee-Cheol Kang
  • J. Korean Med. Sci..2019 Apr;34(12):e105. doi: 10.3346/jkms.2019.34.e105.Epub 2019-03-22.

公衆衛生栄養に影響を与えることができるオーストラリアのスーパーマーケットの政策の性質と質、およびその実践的な適用の証拠。横断的研究

The Nature and Quality of Australian Supermarkets' Policies that can Impact Public Health Nutrition, and Evidence of their Practical Application: A Cross-Sectional Study.
  • Claire Elizabeth Pulker
  • Georgina S A Trapp
  • Jane Anne Scott
  • Christina Mary Pollard
  • Nutrients.2019 Apr;11(4). E853. doi: 10.3390/nu11040853.Epub 2019-04-15.

高血圧改善作用を有する新規フルオロ置換ベンズイミダゾール誘導体の設計、合成および生物学的評価

Design, synthesis and biological evaluation of novel fluoro-substituted benzimidazole derivatives with anti-hypertension activities.
  • Zhuo Wu
  • Ming-Bao Xia
  • D Bertsetseg
  • Yan-Hui Wang
  • Xiao-Lu Bao
  • Wei-Bo Zhu
  • Tao-Xu
  • Pei-Ran Chen
  • He-Sheng Tang
  • Yi-Jia Yan
  • Zhi-Long Chen
  • Bioorg. Chem..2020 Jun;101:104042. S0045-2068(20)31339-0. doi: 10.1016/j.bioorg.2020.104042.Epub 2020-06-26.

2 型糖尿病における長期血圧変動、高血圧症の発症率、腎機能の変化

Long-term blood pressure variability, incidence of hypertension and changes in renal function in type 2 diabetes.
  • Francesca Viazzi
  • Elisa Russo
  • Antonio Mirijello
  • Paola Fioretto
  • Carlo Giorda
  • Antonio Ceriello
  • Massimiliano Copetti
  • Giuseppina T Russo
  • Paolo Di Bartolo
  • Valeria Manicardi
  • Giovanna Leoncini
  • Salvatore De Cosmo
  • Roberto Pontremoli
  • J. Hypertens..2020 Jul;doi: 10.1097/HJH.0000000000002543.Epub 2020-07-06.

老化はミトコンドリアの動態を核分裂にシフトさせ、生殖幹細胞の消失を促進する

Aging shifts mitochondrial dynamics toward fission to promote germline stem cell loss.
  • Oyundari Amartuvshin
  • Chi-Hung Lin
  • Shao-Chun Hsu
  • Shih-Han Kao
  • Alvin Chen
  • Wei-Chun Tang
  • Han-Lin Chou
  • Dong-Lin Chang
  • Yen-Yang Hsu
  • Bai-Shiou Hsiao
  • Elham Rastegari
  • Kun-Yang Lin
  • Yu-Ting Wang
  • Chi-Kuang Yao
  • Guang-Chao Chen
  • Bi-Chang Chen
  • Hwei-Jan Hsu
  • Aging Cell.2020 Jul;:e13191. doi: 10.1111/acel.13191.Epub 2020-07-14.

肝CPT1A遺伝子治療はマウスの食事誘発性肝性ステアトーシスを減少させ、ヒトNAFLDの潜在的な脂質バイオマーカーを明らかにした

Liver CPT1A gene therapy reduces diet-induced hepatic steatosis in mice and highlights potential lipid biomarkers for human NAFLD.
  • Minéia Weber
  • Paula Mera
  • Josefina Casas
  • Javier Salvador
  • Amaia Rodríguez
  • Sergio Alonso
  • David Sebastián
  • M Carmen Soler-Vázquez
  • Carla Montironi
  • Sandra Recalde
  • Raquel Fucho
  • María Calderón-Domínguez
  • Joan Francesc Mir
  • Ramon Bartrons
  • Joan Carles Escola-Gil
  • David Sánchez-Infantes
  • Antonio Zorzano
  • Vicenta Llorente-Cortes
  • Núria Casals
  • Víctor Valentí
  • Gema Frühbeck
  • Laura Herrero
  • Dolors Serra
  • FASEB J..2020 Jul;doi: 10.1096/fj.202000678R.Epub 2020-07-15.

エルロチニブ投与後の乾燥肌と角質層の細胞間脂質組成との関連

Association of dry skin with intercellular lipid composition of stratum corneum after erlotinib administration.
  • Tomonobu Uchino
  • Hiyori Fujino
  • Daichi Kamiya
  • Tomonori Suzuki
  • Yasunori Miyazaki
  • Kazuhiro Asada
  • Toshihiro Shirai
  • Hiroaki Yagi
  • Yuko Sano
  • Mutsumi Moriki
  • Hajime Mizuno
  • Kenichiro Todoroki
  • Midori Kimura
  • Yoshiyuki Kagawa
  • Cancer Chemother. Pharmacol..2020 Jul;10.1007/s00280-020-04095-z. doi: 10.1007/s00280-020-04095-z.Epub 2020-07-15.

アルギン酸ペクチンマイクロゲルにカプセル化されたLactobacillus salivarius LI01は、ラットにおけるD-ガラクトサミン誘発性急性肝障害を改善する

Lactobacillus salivarius LI01 encapsulated in alginate-pectin microgels ameliorates D-galactosamine-induced acute liver injury in rats.
  • Aoxiang Zhuge
  • Bo Li
  • Yin Yuan
  • Longxian Lv
  • Yating Li
  • Jingjing Wu
  • Liya Yang
  • Xiaoyuan Bian
  • Kaicen Wang
  • Qiangqiang Wang
  • Ren Yan
  • Xueling Zhu
  • Lanjuan Li
  • Appl. Microbiol. Biotechnol..2020 Jul;10.1007/s00253-020-10749-y. doi: 10.1007/s00253-020-10749-y.Epub 2020-07-14.

ゴーシェ病患者の治療効率は、乾燥血痕中のリソソーム-Gb1濃度の定量化によって確実にモニターできる

Treatment Efficiency in Gaucher Patients Can Reliably Be Monitored by Quantification of Lyso-Gb1 Concentrations in Dried Blood Spots.
  • Claudia Cozma
  • Paskal Cullufi
  • Guido Kramp
  • Marina Hovakimyan
  • Virtut Velmishi
  • Agim Gjikopulli
  • Sonila Tomori
  • Steffen Fischer
  • Sebastian Oppermann
  • Ulrike Grittner
  • Peter Bauer
  • Christian Beetz
  • Arndt Rolfs
  • Int J Mol Sci.2020 Jun;21(13). E4577. doi: 10.3390/ijms21134577.Epub 2020-06-27.

不飽和ラム脂質前駆体3-(3-ヒドロキシアルカノイルオキシ)アルカン酸の二重結合の局在性を液体クロマトグラフィー-質量分析法を用いてオンラインPaternò-Büchi反応を適用して調べた

Double bond localization in unsaturated rhamnolipid precursors 3-(3-hydroxyalkanoyloxy)alkanoic acids by liquid chromatography-mass spectrometry applying online Paternò-Büchi reaction.
  • Viola Jeck
  • Matti Froning
  • Till Tiso
  • Lars M Blank
  • Heiko Hayen
  • Anal Bioanal Chem.2020 Jul;10.1007/s00216-020-02776-5. doi: 10.1007/s00216-020-02776-5.Epub 2020-07-05.

難治性または再発低悪性度神経膠腫の小児、青年、若年成人を対象としたビンブラスチンとニロチニブの併用療法の第I相試験

Phase I study of vinblastine in combination with nilotinib in children, adolescents, and young adults with refractory or recurrent low-grade glioma.
  • Stephanie Vairy
  • Gwénaël Le Teuff
  • Francisco Bautista
  • Emilie De Carli
  • Anne-Isabelle Bertozzi
  • Anne Pagnier
  • Fanny Fouyssac
  • Karsten Nysom
  • Isabelle Aerts
  • Pierre Leblond
  • Frederic Millot
  • Claire Berger
  • Sandra Canale
  • Angelo Paci
  • Vianney Poinsignon
  • Aurelie Chevance
  • Monia Ezzalfani
  • Dominique Vidaud
  • Angela Di Giannatale
  • Raquel Hladun-Alvaro
  • Francois M Petit
  • Gilles Vassal
  • Birgit Geoerger
  • Marie-Cécile Le Deley
  • Jacques Grill
  • Neurooncol Adv.2020 Jan-Dec;2(1):vdaa075. vdaa075. doi: 10.1093/noajnl/vdaa075.Epub 2020-06-09.

Nur77は、半不変型ナチュラルキラーT細胞における耐性誘導、末端分化、エフェクター機能を制御している

Nur77 controls tolerance induction, terminal differentiation, and effector functions in semi-invariant natural killer T cells.
  • Amrendra Kumar
  • Timothy M Hill
  • Laura E Gordy
  • Naveenchandra Suryadevara
  • Lan Wu
  • Andrew I Flyak
  • Jelena S Bezbradica
  • Luc Van Kaer
  • Sebastian Joyce
  • Proc. Natl. Acad. Sci. U.S.A..2020 Jul;202001665. doi: 10.1073/pnas.2001665117.Epub 2020-07-01.

シングルゲノムシークエンシングを用いた HIV 感染男性と性交渉を行った HIV 感染男性における C 型肝炎の感染経路の評価

Assessing routes of hepatitis C transmission in HIV-infected men who have sex with men using single genome sequencing.
  • Hui Li
  • Kristen M Marks
  • Andrew H Talal
  • Wouter O van Seggelen
  • Bisher Akil
  • Asa Radix
  • Shirish Huprikar
  • Andrea D Branch
  • Shuyi Wang
  • George M Shaw
  • Daniel S Fierer
  • PLoS ONE.2020;15(7):e0235237. PONE-D-20-06018. doi: 10.1371/journal.pone.0235237.Epub 2020-07-15.

パートナー通知のモバイルヘルスサービスを提供することにより、MSMをHIVおよびその他の性感染症から保護する:実用的な段階的ウェッジクラスター無作為化比較試験のプロトコル

Protect MSM from HIV and other sexually transmitted diseases by providing mobile health services of partner notification: protocol for a pragmatic stepped wedge cluster randomized controlled trial.
  • Xiangyu Yan
  • Yongjie Li
  • Hexuan Su
  • Yi Xing
  • Bo Zhang
  • Zuhong Lu
  • Zhongwei Jia
  • BMC Public Health.2020 Jul;20(1):1107. 10.1186/s12889-020-09162-x. doi: 10.1186/s12889-020-09162-x.Epub 2020-07-14.

HCV関連肝細胞がんにおける調節性B細胞およびそのサイトカインプロファイル:調節性T細胞および疾患進行との関連

Regulatory B Cells and Their Cytokine Profile in HCV-Related Hepatocellular Carcinoma: Association with Regulatory T Cells and Disease Progression.
  • Helal F Hetta
  • Mohamed A Mekky
  • Asmaa M Zahran
  • Mohamed O Abdel-Malek
  • Haidi K Ramadan
  • Engy A Shafik
  • Wael A Abbas
  • Muhammad Abbas El-Masry
  • Nahed A Mohamed
  • Amira A Kamel
  • Najat Marraiki
  • Amany Magdy Beshbishy
  • Gaber El-Saber Batiha
  • Heba A Osman
  • Gopala Koneru
  • Mohamed A El-Mokhtar
  • Vaccines (Basel).2020 Jul;8(3). E380. doi: 10.3390/vaccines8030380.Epub 2020-07-11.

直接抗ウイルス剤によるC型肝炎ウイルスの除菌は、進行性肝線維症患者の酸化ストレスを緩和する

Hepatitis C virus eradication by direct antiviral agents abates oxidative stress in patients with advanced liver fibrosis.
  • Federico Salomone
  • Salvatore Petta
  • Agnieszka Micek
  • Rosaria Maria Pipitone
  • Alfio Distefano
  • Carlo Castruccio Castracane
  • Francesca Rini
  • Michelino Di Rosa
  • Concetta Gardi
  • Vincenza Calvaruso
  • Vito Di Marco
  • Giovanni Li Volti
  • Stefania Grimaudo
  • Antonio Craxì
  • Liver Int..2020 Jul;doi: 10.1111/liv.14608.Epub 2020-07-15.

血清サンプル中のウイルス性 B 型および C 型肝炎スクリーニングのための市販の迅速診断検査の感度と特異度

Sensitivity and specificity of commercially available rapid diagnostic tests for viral hepatitis B and C screening in serum samples.
  • Ganbolor Jargalsaikhan
  • Miriam Eichner
  • Delgerbat Boldbaatar
  • Purevjargal Bat-Ulzii
  • Oyungerel Lkhagva-Ochir
  • Odgerel Oidovsambuu
  • Bekhbold Dashtseren
  • Erdenebayar Namjil
  • Zulkhuu Genden
  • Dahgwahdorj Yagaanbuyant
  • Alimaa Tuya
  • Naran Gurjav
  • Altankhuu Mordorj
  • Andreas Bungert
  • Naranbaatar Dashdorj
  • Naranjargal Dashdorj
  • PLoS ONE.2020;15(7):e0235036. PONE-D-19-25400. doi: 10.1371/journal.pone.0235036.Epub 2020-07-15.

イングランドにおける抗生物質の処方に対する質の高いプレミアム制度の影響のメカニズムと効果の差を調べる:縦断的研究

Investigating the mechanism of impact and differential effect of the Quality Premium scheme on antibiotic prescribing in England: a longitudinal study.
  • Philip Emeka Anyanwu
  • Koen Pouwels
  • Anne Walker
  • Michael Moore
  • Azeem Majeed
  • Benedict W J Hayhoe
  • Sarah Tonkin-Crine
  • Aleksandra Borek
  • Susan Hopkins
  • Monsey Mcleod
  • Céire Costelloe
  • BJGP Open.2020 Jul;bjgpopen20X101052. doi: 10.3399/bjgpopen20X101052.Epub 2020-07-14.

臭化アルキルトリメチルアンモニウムを担持した接着性レジンの化学的、機械的、生物学的特性(英文

Chemical, Mechanical and Biological Properties of an Adhesive Resin with Alkyl Trimethyl Ammonium Bromide-loaded Halloysite Nanotubes.
  • Isadora Martini Garcia
  • Vicente Castelo Branco Leitune
  • Rodrigo Alex Arthur
  • Julia Nunes
  • Fernanda Visioli
  • Massimo Giovarruscio
  • Salvatore Sauro
  • Fabrício Mezzomo Collares
  • J Adhes Dent.2020;22(4):399-407. 44871. doi: 10.3290/j.jad.a44871.

感受性ブドウ球菌、連鎖球菌または腸球菌による左側心内膜炎(RODEO)における経口スイッチ対標準静脈内抗生物質療法:2つの非盲検ランダム化比較試験のプロトコール

Oral switch versus standard intravenous antibiotic therapy in left-sided endocarditis due to susceptible staphylococci, streptococci or enterococci (RODEO): a protocol for two open-label randomised controlled trials.
  • Adrien Lemaignen
  • Louis Bernard
  • Pierre Tattevin
  • Jean-Pierre Bru
  • Xavier Duval
  • Bruno Hoen
  • Solène Brunet-Houdard
  • Jean-Luc Mainardi
  • Agnes Caille
  • BMJ Open.2020 Jul;10(7):e033540. bmjopen-2019-033540. doi: 10.1136/bmjopen-2019-033540.Epub 2020-07-14.