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日本語AIでPubMedを検索

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日本語AIでPubMedを検索

PubMedの提供する医学論文データベースを日本語で検索できます。AI(Deep Learning)を活用した機械翻訳エンジンにより、精度高く日本語へ翻訳された論文をご参照いただけます。
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みんなが読んでいる論文

大動脈経カテーテル大動脈弁留置術を受けた患者に対する意識的鎮静のみと比較した併用催眠療法の周術期成績

Perioperative Outcomes of Adjunctive Hypnotherapy Compared with Conscious Sedation Alone for Patients Undergoing Transfemoral Transcatheter Aortic Valve Implantation.
  • Masao Takahashi
  • Gauthier Mouillet
  • Asmaa Khaled
  • Madjid Boukantar
  • Romain Gallet
  • Vladimir Rubimbura
  • Pascal Lim
  • Jean-Luc Dubois-Rande
  • Emmanuel Teiger
  • Int Heart J.2020 Jan;61(1):60-66. doi: 10.1536/ihj.19-296.Epub 2020-01-17.

視床下部発生の分子設計

Molecular design of hypothalamus development.
  • Roman A Romanov
  • Evgenii O Tretiakov
  • Maria Eleni Kastriti
  • Maja Zupancic
  • Martin Häring
  • Solomiia Korchynska
  • Konstantin Popadin
  • Marco Benevento
  • Patrick Rebernik
  • Francois Lallemend
  • Katsuhiko Nishimori
  • Frédéric Clotman
  • William D Andrews
  • John G Parnavelas
  • Matthias Farlik
  • Christoph Bock
  • Igor Adameyko
  • Tomas Hökfelt
  • Erik Keimpema
  • Tibor Harkany
  • Nature.2020 06;582(7811):246-252. 10.1038/s41586-020-2266-0. doi: 10.1038/s41586-020-2266-0.Epub 2020-05-06.

欧州における健康研究の分断化の克服：COVID-19からの教訓

Overcoming fragmentation of health research in Europe: lessons from COVID-19.
  • Karin R Sipido
  • Fernando Antoñanzas
  • Julio Celis
  • Laurent Degos
  • Richard Frackowiak
  • Valentin Fuster
  • Detlev Ganten
  • Steffen Gay
  • Hans Hofstraat
  • Stephen T Holgate
  • Gabriel Krestin
  • Michael Manns
  • Francoise Meunier
  • Wolfgang Oertel
  • Susanna Palkonen
  • Dainius Pavalkis
  • Helga Rübsamen-Schaeff
  • Ulf Smith
  • Bente Merete Stallknecht
  • Tomáš Zima
  • Lancet.2020 06;395(10242):1970-1971. S0140-6736(20)31411-2. doi: 10.1016/S0140-6736(20)31411-2.Epub 2020-06-16.

ミリ秒 H/D 交換質量分析を使用した血管内皮成長因子 A の拡張コンストラクト上での臨床前の Bevacizumab (Avastin) バイオシミラーのエピトープ マッピング

Epitope Mapping for a Pre-Clinical Bevacizumab (Avastin) Biosimilar on an Extended Construct of Vascular Endothelial Growth Factor-A using Millisecond H/D Exchange Mass Spectrometry.
  • Kerene A Brown
  • Cristina Lento
  • Shanthi Rajendran
  • Jason Dowd
  • Derek J Wilson
  • Biochemistry.2020 Jul;doi: 10.1021/acs.biochem.0c00308.Epub 2020-07-16.

ノースカロライナ州におけるMPID-NGSによる最近のHIV感染、薬剤耐性変異、および感染ネットワークのほぼリアルタイム同定

Near Real-Time Identification of Recent HIV Transmissions, Transmitted Drug Resistance Mutations, and Transmission Networks by MPID-NGS in North Carolina.
  • Shuntai Zhou
  • Sabrina Sizemore
  • Matt Moeser
  • Scott Zimmerman
  • Erika Samoff
  • Victoria Mobley
  • Simon Frost
  • Andy Cressman
  • Michael Clark
  • Tara Skelly
  • Hemant Kelkar
  • Umadevi Veluvolu
  • Corbin Jones
  • Joseph Eron
  • Myron Cohen
  • Julie A E Nelson
  • Ronald Swanstrom
  • Ann M Dennis
  • J. Infect. Dis..2020 Jul;jiaa417. doi: 10.1093/infdis/jiaa417.Epub 2020-07-14.

Plasmodium vivax Merozoite Surface Protein 3αに対する相補固定抗体の誘導と動態、免疫グロブリンGサブクラスおよび免疫グロブリンMとの関係について

Induction and Kinetics of Complement-Fixing Antibodies Against Plasmodium vivax Merozoite Surface Protein 3α and Relationship With Immunoglobulin G Subclasses and Immunoglobulin M.
  • Damian A Oyong
  • Danny W Wilson
  • Bridget E Barber
  • Timothy William
  • Jianlin Jiang
  • Mary R Galinski
  • Freya J I Fowkes
  • Matthew J Grigg
  • James G Beeson
  • Nicholas M Anstey
  • Michelle J Boyle
  • J. Infect. Dis..2019 11;220(12):1950-1961. 5550848. doi: 10.1093/infdis/jiz407.

ミノサイクリンとメチルプレドニゾロンの併用治療が実験的脊髄損傷における腫瘍壊死因子αとインターロイキン-6の発現に及ぼす影響：光と電子顕微鏡による研究

Effects of combined treatment of minocycline and methylprednisolone on the expression of tumor necrosis factor alpha and interleukine-6 in experimental spinal cord injury: a light and electron microscopic study.
  • Leman Sencar
  • Derviş Mansuri Yilmaz
  • Abdullah Tuli
  • Sait Polat
  • Ultrastruct Pathol.2020 Jun;:1-17. doi: 10.1080/01913123.2020.1771493.Epub 2020-06-22.

羽毛型TCF7L2はニコチン中毒と糖尿病を結びつける

Habenular TCF7L2 links nicotine addiction to diabetes.
  • Alexander Duncan
  • Mary P Heyer
  • Masago Ishikawa
  • Stephanie P B Caligiuri
  • Xin-An Liu
  • Zuxin Chen
  • Maria Vittoria Micioni Di Bonaventura
  • Karim S Elayouby
  • Jessica L Ables
  • William M Howe
  • Purva Bali
  • Clementine Fillinger
  • Maya Williams
  • Richard M O'Connor
  • Zichen Wang
  • Qun Lu
  • Theodore M Kamenecka
  • Avi Ma'ayan
  • Heidi C O'Neill
  • Ines Ibanez-Tallon
  • Aron M Geurts
  • Paul J Kenny
  • Nature.2019 10;574(7778):372-377. 10.1038/s41586-019-1653-x. doi: 10.1038/s41586-019-1653-x.Epub 2019-10-16.

チチンのC末端PEVKエクソンを削除すると、受動的な筋剛性が増加し、スプライシングが変化し、骨格筋の断面および縦方向の肥大が誘導されることが明らかになった

Deleting Titin's C-Terminal PEVK Exons Increases Passive Stiffness, Alters Splicing, and Induces Cross-Sectional and Longitudinal Hypertrophy in Skeletal Muscle.
  • Robbert J van der Pijl
  • Brian Hudson
  • Tomotaroh Granzier-Nakajima
  • Frank Li
  • Anne M Knottnerus
  • John Smith
  • Charles S Chung
  • Michael Gotthardt
  • Henk L Granzier
  • Coen A C Ottenheijm
  • Front Physiol.2020;11:494. doi: 10.3389/fphys.2020.00494.Epub 2020-05-29.

心筋β-アドレナリン受容体の活性化は、コンネキシン43の発現と分布における細胞タイプ依存性の異なる変化を媒介する

Cardiac β-adrenergic receptor activation mediates distinct and cell type-dependent changes in the expression and distribution of connexin 43.
  • Yi Zhang
  • Meng-Chen Hou
  • Jing-Jing Li
  • Ying Qi
  • Yu Zhang
  • Gang She
  • Yu-Jie Ren
  • Wei Wu
  • Zheng-Da Pang
  • Wenjun Xie
  • Xiu-Ling Deng
  • Xiao-Jun Du
  • J. Cell. Mol. Med..2020 Jun;doi: 10.1111/jcmm.15469.Epub 2020-06-24.

グリーンルーフの5年間の運用において、廃材をグリーンルーフ下地として再利用することで、グリーンルーフからの炭素排出を効果的に抑制できるかどうか？

Whether the carbon emission from green roofs can be effectively mitigated by recycling waste building material as green roof substrate during five-year operation?
  • Liangqian Fan
  • Jingting Wang
  • Xiaoling Liu
  • Hongbing Luo
  • Ke Zhang
  • Xiaoying Fu
  • Mei Li
  • Xiaoting Li
  • Bing Jiang
  • Jia Chen
  • Shuzhi Fu
  • You Mo
  • Lin Li
  • Wei Chen
  • Lin Cheng
  • Fenghui Chen
  • Lin Ji
  • Dandan Ma
  • Xiaohong Zhang
  • Bruce C Anderson
  • Environ Sci Pollut Res Int.2020 Jul;10.1007/s11356-020-09896-6. doi: 10.1007/s11356-020-09896-6.Epub 2020-07-17.

悪性尿路閉塞症治療における二重JカテーテルのAntegrade挿入：大学病院における修正術式で得られた結果のレトロスペクティブ解析

Antegrade insertion of a double J catheter in the treatment of malignant ureteral obstruction: a retrospective analysis of the results obtained with a modified technique at a university hospital.
  • Rômulo Florêncio Tristão Santos
  • Tiago Kojun Tibana
  • Edson Marchiori
  • Thiago Franchi Nunes
  • Radiol Bras.2020 May-Jun;53(3):155-160. doi: 10.1590/0100-3984.2019.0090.

BDNFの過剰発現は線条体神経細胞のD3受容体レベルを増加させ、D1受容体アゴニスト誘発性ジスキネジアを悪化させる

BDNF Overexpression Increases Striatal D3 Receptor Level at Striatal Neurons and Exacerbates D1-Receptor Agonist-Induced Dyskinesia.
  • Simona Scheggi
  • Francesca Rossi
  • Sara Corsi
  • Silvia Fanni
  • Elisabetta Tronci
  • Congiu Ludovica
  • Romina Vargiu
  • Carla Gambarana
  • Ana Muñoz
  • Roberto Stancampiano
  • Anders Bjorklund
  • Manolo Carta
  • J Parkinsons Dis.2020 Jul;JPD202061. doi: 10.3233/JPD-202061.Epub 2020-07-08.

ヒストン脱アセチル化酵素6/8とブロモドメインBRPF1のデュアルターゲティング阻害剤の設計、合成、生物学的評価

Design, synthesis, and biological evaluation of dual targeting inhibitors of histone deacetylase 6/8 and bromodomain BRPF1.
  • Ehab Ghazy
  • Patrik Zeyen
  • Daniel Herp
  • Martin Hügle
  • Karin Schmidtkunz
  • Frank Erdmann
  • Dina Robaa
  • Matthias Schmidt
  • Elizabeth R Morales
  • Christophe Romier
  • Stefan Günther
  • Manfred Jung
  • Wolfgang Sippl
  • Eur J Med Chem.2020 Aug;200:112338. S0223-5234(20)30307-X. doi: 10.1016/j.ejmech.2020.112338.Epub 2020-05-18.

Mthfd2はミトコンドリア機能とDNA修復を調節し、マウス幹細胞の多能性を維持する

Mthfd2 Modulates Mitochondrial Function and DNA Repair to Maintain the Pluripotency of Mouse Stem Cells.
  • Liang Yue
  • Yangli Pei
  • Liang Zhong
  • Henry Yang
  • Yanliang Wang
  • Wei Zhang
  • Naixin Chen
  • Qianqian Zhu
  • Jie Gao
  • Minglei Zhi
  • Bingqiang Wen
  • Shaopeng Zhang
  • Jinzhu Xiang
  • Qingqing Wei
  • Hui Liang
  • Suying Cao
  • Huiqiang Lou
  • Zhongzhou Chen
  • Jianyong Han
  • Stem Cell Reports.2020 Jul;S2213-6711(20)30239-3. doi: 10.1016/j.stemcr.2020.06.018.Epub 2020-07-02.

リンパ性新生物における全ゲノムシークエンシングから免疫グロブリン遺伝子再配列と発がん性転座を再構築するためのIgCaller

IgCaller for reconstructing immunoglobulin gene rearrangements and oncogenic translocations from whole-genome sequencing in lymphoid neoplasms.
  • Ferran Nadeu
  • Rut Mas-de-Les-Valls
  • Alba Navarro
  • Romina Royo
  • Silvia Martín
  • Neus Villamor
  • Helena Suárez-Cisneros
  • Rosó Mares
  • Junyan Lu
  • Anna Enjuanes
  • Alfredo Rivas-Delgado
  • Marta Aymerich
  • Tycho Baumann
  • Dolors Colomer
  • Julio Delgado
  • Ryan D Morin
  • Thorsten Zenz
  • Xose S Puente
  • Peter J Campbell
  • Sílvia Beà
  • Francesco Maura
  • Elías Campo
  • Nat Commun.2020 Jul;11(1):3390. 10.1038/s41467-020-17095-7. doi: 10.1038/s41467-020-17095-7.Epub 2020-07-07.

Corrigendum to "Partial least squares and linear support vector regression chemometric models for analysis of Norfloxacin and Tinidazole with Tinidazole impurity" Spectrochim.Acta A: Mol.Biomol.Spectrosc.239巻、2020年10月5日、118513

Corrigendum to "Partial least squares and linear support vector regression chemometric models for analysis of Norfloxacin and Tinidazole with Tinidazole impurity" [Spectrochim. Acta A: Mol. Biomol. Spectrosc. Volume 239, 5 October 2020, 118513].
  • Ibrahim A Naguib
  • Eglal A Abdelaleem
  • Eman S Hassan
  • Nouruddin W Ali
  • Mohammed Gamal
  • Spectrochim Acta A Mol Biomol Spectrosc.2020 Jul;241:118696. S1386-1425(20)30675-2. doi: 10.1016/j.saa.2020.118696.Epub 2020-07-13.

腎生検後の糸球体腎炎患者におけるがん発症と死亡率の差：単一施設レトロスペクティブコホート研究

Cancer development and mortality differences in patients with glomerulonephritis after renal biopsy: a single center retrospective cohort study.
  • Hyunjin Ryu
  • Kipyo Kim
  • Jiwon Ryu
  • Hyung-Eun Son
  • Ji-Young Ryu
  • Sejoong Kim
  • Ki Young Na
  • Dong Wan Chae
  • Ho Jun Chin
  • BMC Nephrol.2020 Jun;21(1):221. 10.1186/s12882-020-01882-x. doi: 10.1186/s12882-020-01882-x.Epub 2020-06-10.

クレードF AAVHSCは、非ヒト霊長類に静脈内投与した後、血液脳関門を通過し、末梢組織に加えて中枢神経系にも導入されます

Clade F AAVHSCs cross the blood brain barrier and transduce the central nervous system in addition to peripheral tissues following intravenous administration in nonhuman primates.
  • Jeff L Ellsworth
  • Jacinthe Gingras
  • Laura J Smith
  • Hillard Rubin
  • Tania A Seabrook
  • Kruti Patel
  • Nicole Zapata
  • Kevin Olivieri
  • Michael O'Callaghan
  • Elizabeth Chlipala
  • Pablo Morales
  • Albert Seymour
  • PLoS ONE.2019;14(11):e0225582. PONE-D-19-21158. doi: 10.1371/journal.pone.0225582.Epub 2019-11-26.

副産物の価値化に伴う課題-超音波処理した植物由来副産物と発酵させた植物由来副産物の安全性パラメータの比較研究

Challenges Associated with Byproducts Valorization-Comparison Study of Safety Parameters of Ultrasonicated and Fermented Plant-Based Byproducts.
  • Elena Bartkiene
  • Vadims Bartkevics
  • Iveta Pugajeva
  • Anastasija Borisova
  • Egle Zokaityte
  • Vita Lele
  • Vytaute Sakiene
  • Paulina Zavistanaviciute
  • Dovile Klupsaite
  • Daiva Zadeike
  • Fatih Özogul
  • Grazina Juodeikiene
  • Foods.2020 May;9(5). E614. doi: 10.3390/foods9050614.Epub 2020-05-11.

PCAREとWASF3は、光受容体外側セグメントディスク形成の開始に必要な毛様体F-アクチンアセンブリを制御しています

PCARE and WASF3 regulate ciliary F-actin assembly that is required for the initiation of photoreceptor outer segment disk formation.
  • Julio C Corral-Serrano
  • Ideke J C Lamers
  • Jeroen van Reeuwijk
  • Lonneke Duijkers
  • Anita D M Hoogendoorn
  • Adem Yildirim
  • Nikoleta Argyrou
  • Renate A A Ruigrok
  • Stef J F Letteboer
  • Rossano Butcher
  • Max D van Essen
  • Sanae Sakami
  • Sylvia E C van Beersum
  • Krzysztof Palczewski
  • Michael E Cheetham
  • Qin Liu
  • Karsten Boldt
  • Uwe Wolfrum
  • Marius Ueffing
  • Alejandro Garanto
  • Ronald Roepman
  • Rob W J Collin
  • Proc. Natl. Acad. Sci. U.S.A..2020 May;117(18):9922-9931. 1903125117. doi: 10.1073/pnas.1903125117.Epub 2020-04-20.

グリオブラストーマの骨髄由来サプレッサー細胞サブセットは、免疫抑制を低減するために標的化できるマクロファージ移行阻害因子受容体のプロファイルを異なる形で発現している

Glioblastoma Myeloid-Derived Suppressor Cell Subsets Express Differential Macrophage Migration Inhibitory Factor Receptor Profiles That Can Be Targeted to Reduce Immune Suppression.
  • Tyler J Alban
  • Defne Bayik
  • Balint Otvos
  • Anja Rabljenovic
  • Lin Leng
  • Leu Jia-Shiun
  • Gustavo Roversi
  • Adam Lauko
  • Arbaz A Momin
  • Alireza M Mohammadi
  • David M Peereboom
  • Manmeet S Ahluwalia
  • Kazuko Matsuda
  • Kyuson Yun
  • Richard Bucala
  • Michael A Vogelbaum
  • Justin D Lathia
  • Front Immunol.2020;11:1191. doi: 10.3389/fimmu.2020.01191.Epub 2020-06-18.

COVID-19 を有する成人入院患者における短期生存率を予測するためのリスク因子に基づくシステムの開発と検証：多施設，レトロスペクティブ，コホート研究

Development and validation of a risk factor-based system to predict short-term survival in adult hospitalized patients with COVID-19: a multicenter, retrospective, cohort study.
  • Shuai Zhang
  • Mengfei Guo
  • Limin Duan
  • Feng Wu
  • Guorong Hu
  • Zhihui Wang
  • Qi Huang
  • Tingting Liao
  • Juanjuan Xu
  • Yanling Ma
  • Zhilei Lv
  • Wenjing Xiao
  • Zilin Zhao
  • Xueyun Tan
  • Daquan Meng
  • Shujing Zhang
  • E Zhou
  • Zhengrong Yin
  • Wei Geng
  • Xuan Wang
  • Jianchu Zhang
  • Jianguo Chen
  • Yu Zhang
  • Yang Jin
  • Crit Care.2020 Jul;24(1):438. 10.1186/s13054-020-03123-x. doi: 10.1186/s13054-020-03123-x.Epub 2020-07-16.

加齢マウスにおけるセラミド発現の組織特異的スクリーニングにより、骨格筋の繊維サイズと強度の潜在的な調節因子としてセラミド合成酵素-1とセラミド合成酵素-5が同定された

A tissue-specific screen of ceramide expression in aged mice identifies ceramide synthase-1 and ceramide synthase-5 as potential regulators of fiber size and strength in skeletal muscle.
  • Bettina Tosetti
  • Susanne Brodesser
  • Anna Brunn
  • Martina Deckert
  • Matthias Blüher
  • Wolfram Doehner
  • Stefan D Anker
  • Daniela Wenzel
  • Bernd Fleischmann
  • Carola Pongratz
  • Franziska Peters
  • Olaf Utermöhlen
  • Martin Krönke
  • Aging Cell.2020 01;19(1):e13049. doi: 10.1111/acel.13049.Epub 2019-11-06.

一般的なピピストレルPipistrellleus pipistrellus (Chiroptera: Vespertilionidae)とコウモリ軟ダニArgas vespertilionis (Ixodida: Argasidae)におけるRickettsiae

Rickettsiae in the common pipistrelle Pipistrellus pipistrellus (Chiroptera: Vespertilionidae) and the bat soft tick Argas vespertilionis (Ixodida: Argasidae).
  • Shuo Zhao
  • Meihua Yang
  • Gang Liu
  • Sándor Hornok
  • Shanshan Zhao
  • Chunli Sang
  • Wenbo Tan
  • Yuanzhi Wang
  • Parasit Vectors.2020 Jan;13(1):10. 10.1186/s13071-020-3885-x. doi: 10.1186/s13071-020-3885-x.Epub 2020-01-09.

インテグリンαvβ3を用いた新血管新生のイメージ化のための有望なターゲットとしてのインテグリンαvβ3のインハウスジェネレーター産生ポジトロンエミッター(68)Ga標識DOTA-アルギニン-グリシン-アスパラギン酸(RGD)リガンドを用いた研究

Integrin αvβ3 as a Promising Target to Image Neoangiogenesis Using In-House Generator-Produced Positron Emitter (68)Ga-Labeled DOTA-Arginine-Glycine-Aspartic Acid (RGD) Ligand.
  • Rakhee Vatsa
  • Priya Bhusari
  • Sunil Kumar
  • Sudipta Chakraborty
  • Ashutosh Dash
  • Gurpreet Singh
  • Devinder Kumar Dhawan
  • Jaya Shukla
  • Bhagwant Rai Mittal
  • Cancer Biother. Radiopharm..2015 Jun;30(5):217-24. doi: 10.1089/cbr.2014.1781.