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日本語AIでPubMedを検索

歯科医師情報サイトTOP / PubMed論文検索

日本語AIでPubMedを検索

PubMedの提供する医学論文データベースを日本語で検索できます。AI(Deep Learning)を活用した機械翻訳エンジンにより、精度高く日本語へ翻訳された論文をご参照いただけます。
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みんなが読んでいる論文

カプサイシン感受性線維は、ラットの外傷性脳損傷後の眼窩周囲のアロディニアと炎症細胞の活性化を媒介している。外傷後頭痛におけるTRPV1チャネルの関与

Capsaicin-sensitive fibers mediate periorbital allodynia and activation of inflammatory cells after traumatic brain injury in rats: Involvement of TRPV1 channels in post-traumatic headache.
  • Fernando da Silva Fiorin
  • Caroline Cunha do Espírito Santo
  • Raphael Santos do Nascimento
  • Gustavo Cassol
  • Evelini Plácido
  • Adair Roberto Soares Santos
  • Jefferson Luiz Brum Marques
  • Patricia S Brocardo
  • Michele Rechia Fighera
  • Luiz Fernando Freire Royes
  • Neuropharmacology.2020 Jun;:108215. S0028-3908(20)30283-5. doi: 10.1016/j.neuropharm.2020.108215.Epub 2020-06-20.

長時間作用型低分子化合物を用いたHIVカプシドタンパク質の臨床的標的化

Clinical targeting of HIV capsid protein with a long-acting small molecule.
  • John O Link
  • Martin S Rhee
  • Winston C Tse
  • Jim Zheng
  • John R Somoza
  • William Rowe
  • Rebecca Begley
  • Anna Chiu
  • Andrew Mulato
  • Derek Hansen
  • Eric Singer
  • Luong K Tsai
  • Rujuta A Bam
  • Chien-Hung Chou
  • Eda Canales
  • Gediminas Brizgys
  • Jennifer R Zhang
  • Jiayao Li
  • Michael Graupe
  • Philip Morganelli
  • Qi Liu
  • Qiaoyin Wu
  • Randall L Halcomb
  • Roland D Saito
  • Scott D Schroeder
  • Scott E Lazerwith
  • Steven Bondy
  • Debi Jin
  • Magdeleine Hung
  • Nikolai Novikov
  • Xiaohong Liu
  • Armando G Villaseñor
  • Carina E Cannizzaro
  • Eric Y Hu
  • Robert L Anderson
  • Todd C Appleby
  • Bing Lu
  • Judy Mwangi
  • Albert Liclican
  • Anita Niedziela-Majka
  • Giuseppe A Papalia
  • Melanie H Wong
  • Stephanie A Leavitt
  • Yili Xu
  • David Koditek
  • George J Stepan
  • Helen Yu
  • Nikos Pagratis
  • Sheila Clancy
  • Shekeba Ahmadyar
  • Terrence Z Cai
  • Scott Sellers
  • Scott A Wolckenhauer
  • John Ling
  • Christian Callebaut
  • Nicolas Margot
  • Renee R Ram
  • Ya-Pei Liu
  • Rob Hyland
  • Gary I Sinclair
  • Peter J Ruane
  • Gordon E Crofoot
  • Cheryl K McDonald
  • Diana M Brainard
  • Latesh Lad
  • Swami Swaminathan
  • Wesley I Sundquist
  • Roman Sakowicz
  • Anne E Chester
  • William E Lee
  • Eric S Daar
  • Stephen R Yant
  • Tomas Cihlar
  • Nature.2020 Jul;10.1038/s41586-020-2443-1. doi: 10.1038/s41586-020-2443-1.Epub 2020-07-01.

急性冠症候群患者における年齢および体重に応じたプラスグレルの投与量とチカグレロールの標準投与量の比較。無作為化試験の結果

Age- and Weight-Adapted Dose of Prasugrel Versus Standard Dose of Ticagrelor in Patients With Acute Coronary Syndromes: Results From a Randomized Trial.
  • Maurizio Menichelli
  • Franz-Josef Neumann
  • Gjin Ndrepepa
  • Katharina Mayer
  • Jochen Wöhrle
  • Isabell Bernlochner
  • Gert Richardt
  • Bernhard Witzenbichler
  • Dirk Sibbing
  • Senta Gewalt
  • Dominick J Angiolillo
  • Shqipdona Lahu
  • Christian W Hamm
  • Alexander Hapfelmeier
  • Dietmar Trenk
  • Karl-Ludwig Laugwitz
  • Heribert Schunkert
  • Stefanie Schüpke
  • Adnan Kastrati
  • Ann. Intern. Med..2020 Jul;doi: 10.7326/M20-1806.Epub 2020-07-21.

ヌクレオチドアナログは、炎症やオートファジーに依存しないβ-カテニンを介して大腸炎関連がんを予防する

A Nucleotide Analog Prevents Colitis-Associated Cancer via Beta-Catenin Independently of Inflammation and Autophagy.
  • Yong Hua Sheng
  • Rabina Giri
  • Julie Davies
  • Veronika Schreiber
  • Saleh Alabbas
  • Ramya Movva
  • Yaowu He
  • Andy Wu
  • John Hooper
  • Brett McWhinney
  • Iulia Oancea
  • Gregor Kijanka
  • Sumaira Hasnain
  • Andrew J Lucke
  • David P Fairlie
  • Michael A McGuckin
  • Timothy H Florin
  • Jakob Begun
  • Cell Mol Gastroenterol Hepatol.2020 Jun;S2352-345X(20)30088-6. doi: 10.1016/j.jcmgh.2020.05.012.Epub 2020-06-01.

AKT2, STK38L, HMGA2, ETS1, E2F5を直接標的としたmiR-493-3pによる卵巣癌細胞のアポトーシス誘導

Induction of apoptosis in ovarian cancer cells by miR-493-3p directly targeting AKT2, STK38L, HMGA2, ETS1 and E2F5.
  • Michael Kleemann
  • Helga Schneider
  • Kristian Unger
  • Jeremias Bereuther
  • Simon Fischer
  • Philip Sander
  • E Marion Schneider
  • Pamela Fischer-Posovszky
  • Christian U Riedel
  • René Handrick
  • Kerstin Otte
  • Cell. Mol. Life Sci..2019 Feb;76(3):539-559. 10.1007/s00018-018-2958-x. doi: 10.1007/s00018-018-2958-x.Epub 2018-11-03.

神経受容体イメージングのための灰白質と血漿中の定常状態CFlumazenilレベルの調整のためのボーラス注入スキーム

Bolus Infusion Scheme for the Adjustment of Steady State [C]Flumazenil Levels in the Grey Matter and in the Blood Plasma for Neuroreceptor Imaging.
  • Jörg Mauler
  • Alexander Heinzel
  • Andreas Matusch
  • Hans Herzog
  • Irene Neuner
  • Jürgen Scheins
  • Christine Wyss
  • Jürgen Dammers
  • Markus Lang
  • Johannes Ermert
  • Bernd Neumaier
  • Karl-Josef Langen
  • N Jon Shah
  • Neuroimage.2020 Jul;:117160. S1053-8119(20)30646-7. doi: 10.1016/j.neuroimage.2020.117160.Epub 2020-07-14.

経静脈的鉛抽出からの主要な合併症と死亡率に対するセンターボリュームとプロシージャの位置の効果：ESC EHRA EORP European Lead Extraction ConTRolled ELECTRa レジストリのサブアナリシス

The effect of centre volume and procedure location on major complications and mortality from transvenous lead extraction: an ESC EHRA EORP European Lead Extraction ConTRolled ELECTRa registry subanalysis.
  • Baldeep S Sidhu
  • Justin Gould
  • Catey Bunce
  • Mark Elliott
  • Vishal Mehta
  • Charles Kennergren
  • Christian Butter
  • Jean-Claude Deharo
  • Andrzej Kutarski
  • Aldo P Maggioni
  • Angelo Auricchio
  • Karl-Heinz Kuck
  • Carina Blomström-Lundqvist
  • Maria Grazia Bongiorni
  • Christopher A Rinaldi
  • Europace.2020 Jul;euaa131. doi: 10.1093/europace/euaa131.Epub 2020-07-20.

定量的肺CTと臨床データを用いた新規コロナウイルス疾患（COVID-19）の評価：短期予後の予測

Evaluation of novel coronavirus disease (COVID-19) using quantitative lung CT and clinical data: prediction of short-term outcome.
  • João Matos
  • Francesco Paparo
  • Ilaria Mussetto
  • Lorenzo Bacigalupo
  • Alessio Veneziano
  • Silvia Perugin Bernardi
  • Ennio Biscaldi
  • Enrico Melani
  • Giancarlo Antonucci
  • Paolo Cremonesi
  • Marco Lattuada
  • Alberto Pilotto
  • Emanuele Pontali
  • Gian Andrea Rollandi
  • Eur Radiol Exp.2020 06;4(1):39. 10.1186/s41747-020-00167-0. doi: 10.1186/s41747-020-00167-0.Epub 2020-06-26.

CLL 患者における COVID-19 のアウトカム：国際的な多施設共同試験の経験

Outcomes of COVID-19 in Patients with CLL: A Multicenter, International Experience.
  • Anthony R Mato
  • Lindsey Elizabeth Roeker
  • Nicole Lamanna
  • John Allan
  • Lori Ann Leslie
  • John M Pagel
  • Krish Patel
  • Anders Osterborg
  • Daniel Wojenski
  • Manali Kamdar
  • Scott F Huntington
  • Matthew S Davids
  • Jennifer R Brown
  • Darko Antic
  • Ryan W Jacobs
  • Inhye E Ahn
  • Jeffrey J Pu
  • Krista Isaac
  • Paul M Barr
  • Chaitra Ujjani
  • Mark Blaine Geyer
  • Ellin Berman
  • Andrew D Zelenetz
  • Nikita Malakhov
  • Richard R Furman
  • Michael Koropsak
  • Neil Bailey
  • Lotta Hansson
  • Guilherme Fleury Perini
  • Shuo Ma
  • Christine E Ryan
  • Adrian Wiestner
  • Craig A Portell
  • Mazyar Shadman
  • Elise A Chong
  • Danielle M Brander
  • Suchitra Sundaram
  • Amanda N Seddon
  • Erlene Seymour
  • Meera Patel
  • Nicolas Martinez-Calle
  • Talha Munir
  • Renata Walewska
  • Angus Broom
  • Harriet Sarah Walter
  • Dima El-Sharkawi
  • Helen Parry
  • Matthew R Wilson
  • Piers E Patten
  • José-Ángel Hernández-Rivas
  • Fatima Miras
  • Noemi Fernández Escalada
  • Paola Ghione
  • Chadi Nabhan
  • Sonia Lebowitz
  • Erica B Bhavsar
  • Javier López-Jiménez
  • Daniel Naya
  • Jose Antonio Garcia-Marco
  • Sigrid S Skånland
  • Raul Cordoba
  • Toby Andrew Eyre
  • Blood.2020 Jul;blood.2020006965. doi: 10.1182/blood.2020006965.Epub 2020-07-20.

2種の熱帯植物（Tetrapleura tetrapteraとQuassia undulata）の水性抽出物は、スコポラミン誘発性健忘症ラットにおいて空間的・非空間的作業記憶を改善した。神経細胞のコリン作動系と抗酸化系の影響

Aqueous extracts of two tropical ethnobotanicals (Tetrapleura tetraptera and Quassia undulata) improved spatial and non-spatial working memories in scopolamine-induced amnesic rats: Influence of neuronal cholinergic and antioxidant systems.
  • Veronica O Odubanjo
  • Emmanuel O Ibukun
  • Ganiyu Oboh
  • Stephen A Adefegha
  • Biomed. Pharmacother..2018 Mar;99:198-204. S0753-3322(17)35005-9. doi: 10.1016/j.biopha.2018.01.043.

心房細動患者における薬剤溶出ステント vs ベアメタルステントの安全性と有効性。システマティックレビューとメタアナリシス

Safety and efficacy of drug eluting stents vs bare metal stents in patients with atrial fibrillation: A systematic review and meta-analysis.
  • Antonia Sambola
  • Pau Rello
  • Toni Soriano
  • Deepak L Bhatt
  • Vinay Pasupuleti
  • Christopher P Cannon
  • C Michael Gibson
  • Willem J M Dewilde
  • Gregory Y H Lip
  • Eric D Peterson
  • K E Juhani Airaksinen
  • Tuomas Kiviniemi
  • Laurent Fauchier
  • Lorenz Räber
  • Juan M Ruiz-Nodar
  • Maciej Banach
  • Héctor Bueno
  • Adrian V Hernandez
  • Thromb. Res..2020 Jul;195:128-135. S0049-3848(20)30301-7. doi: 10.1016/j.thromres.2020.07.010.Epub 2020-07-09.

米国成人の間でのアルコール関与の段階での幼少期の不利な経験（ACE）と移行。進行と回帰

Adverse childhood experiences (ACEs) and transitions in stages of alcohol involvement among US adults: Progression and regression.
  • Anika A H Alvanzo
  • Carla L Storr
  • Beth Reboussin
  • Kerry M Green
  • Ramin Mojtabai
  • Lareina N La Flair
  • Bernadette A Cullen
  • Ryoko Susukida
  • Marissa Seamans
  • Rosa M Crum
  • Child Abuse Negl.2020 Jul;107:104624. S0145-2134(20)30279-9. doi: 10.1016/j.chiabu.2020.104624.Epub 2020-07-16.

バングラデシュにおける養殖および野生由来の淡水エビ（Macrobrachium rosenbergii）における微量金属の生物濃縮とヒトの健康リスク評価

Bioaccumulation of trace metals in freshwater prawn, Macrobrachium rosenbergii from farmed and wild sources and human health risk assessment in Bangladesh.
  • Farhana Mostafiz
  • Md Monirul Islam
  • Badhan Saha
  • Md Kamal Hossain
  • Mohammad Moniruzzaman
  • Md Habibullah-Al-Mamun
  • Environ Sci Pollut Res Int.2020 May;27(14):16426-16438. 10.1007/s11356-020-08028-4. doi: 10.1007/s11356-020-08028-4.Epub 2020-03-02.

メラノーマのMCL1バイアスを標的にすると、BRAFとERK1/2経路阻害剤のアポトーシスの可能性が解き放たれる

Targeting melanoma's MCL1 bias unleashes the apoptotic potential of BRAF and ERK1/2 pathway inhibitors.
  • Matthew J Sale
  • Emma Minihane
  • Noel R Monks
  • Rebecca Gilley
  • Frances M Richards
  • Kevin P Schifferli
  • Courtney L Andersen
  • Emma J Davies
  • Mario Aladren Vicente
  • Eiko Ozono
  • Aleksandra Markovets
  • Jonathan R Dry
  • Lisa Drew
  • Vikki Flemington
  • Theresa Proia
  • Duncan I Jodrell
  • Paul D Smith
  • Simon J Cook
  • Nat Commun.2019 11;10(1):5167. 10.1038/s41467-019-12409-w. doi: 10.1038/s41467-019-12409-w.Epub 2019-11-14.

遅発性ハザードに対する稲作農家の適応策に影響を与える要因：フィリピンとベトナムにおける塩水浸水の事例

Factors Influencing Measure-based Adaptation of Rice Farmers for Slow-Onset Hazard: the Case of Saltwater Inundation in the Philippines and Vietnam.
  • Catherine Roween C Almaden
  • Thanh Tung Diep
  • Agnes C Rola
  • Rowena D T Baconguis
  • Juan M Pulhin
  • Jose V Camacho
  • Rico C Ancog
  • Environ Manage.2020 Jul;10.1007/s00267-020-01332-2. doi: 10.1007/s00267-020-01332-2.Epub 2020-07-17.

足底筋膜症患者に対する橈骨体外衝撃波治療（rESWT）、sham-rESWT、標準化された運動プログラム、または通常のケアの有効性：二重盲検、無作為化、シャムコントロール試験の試験プロトコール

The effectiveness of radial extracorporeal shock wave therapy (rESWT), sham-rESWT, standardised exercise programme or usual care for patients with plantar fasciopathy: study protocol for a double-blind, randomised, sham-controlled trial.
  • Marte Heide
  • Marianne Mørk
  • Cecilie Røe
  • Jens Ivar Brox
  • Aasne Fenne Hoksrud
  • Trials.2020 Jun;21(1):589. 10.1186/s13063-020-04510-z. doi: 10.1186/s13063-020-04510-z.Epub 2020-06-29.

ブラジル北東部、アラリペ盆地のロムアルド層（アルビアン）の基底部に生息する最初の獣脚類恐竜（コエロサウルス属、セロポダ）

The first theropod dinosaur (Coelurosauria, Theropoda) from the base of the Romualdo Formation (Albian), Araripe Basin, Northeast Brazil.
  • Juliana Manso Sayão
  • Antônio Álamo Feitosa Saraiva
  • Arthur Souza Brum
  • Renan Alfredo Machado Bantim
  • Rafael Cesar Lima Pedroso de Andrade
  • Xin Cheng
  • Flaviana Jorge de Lima
  • Helder de Paula Silva
  • Alexander W A Kellner
  • Sci Rep.2020 Jul;10(1):10892. 10.1038/s41598-020-67822-9. doi: 10.1038/s41598-020-67822-9.Epub 2020-07-10.

レースのペーシングの早期シフトは、睡眠不足下でのシングル・エクササイズ・ウルトラマラソンにおける将来のパフォーマンスを予測することができる

Earlier shift in race pacing can predict future performance during a single-effort ultramarathon under sleep deprivation.
  • Allison J Brager
  • Sukru Demiral
  • John Choynowski
  • Jess Kim
  • Bill Campbell
  • Vincent F Capaldi
  • Guido Simonelli
  • Steve Hammer
  • Sleep Sci.2020 Jan-Mar;13(1):25-31. doi: 10.5935/1984-0063.20190132.

同種造血幹細胞移植を受けている成人ハイリスク急性リンパ芽球性白血病患者に対する TMLI と非 TMLI の条件付けレジメンの転帰の比較：単一施設での経験

Comparing the outcomes between TMLI and non-TMLI conditioning regimens for adult high-risk acute lymphoblastic leukemia patients undergoing allogeneic hematopoietic stem cell transplantation: a single-center experience.
  • Xiaoyan Zhao
  • Xuan Lu
  • Liang Tang
  • Han Yan
  • Wenlan Chen
  • Wei Shi
  • Zhaodong Zhong
  • Yong You
  • Linghui Xia
  • Yu Hu
  • Huafang Wang
  • Leuk. Lymphoma.2020 Jul;:1-9. doi: 10.1080/10428194.2020.1789621.Epub 2020-07-10.

難治性ランゲルハンス細胞組織球症の小児における造血幹細胞移植の全国的なレトロスペクティブレビュー

Nationwide retrospective review of hematopoietic stem cell transplantation in children with refractory Langerhans cell histiocytosis.
  • Kazuko Kudo
  • Miho Maeda
  • Nobuhiro Suzuki
  • Hirokazu Kanegane
  • Shouichi Ohga
  • Eiichi Ishii
  • Yoko Shioda
  • Toshihiko Imamura
  • Shinsaku Imashuku
  • Yukiko Tsunematsu
  • Mikiya Endo
  • Akira Shimada
  • Yuuki Koga
  • Yoshiko Hashii
  • Maiko Noguchi
  • Masami Inoue
  • Ken Tabuchi
  • Akira Morimoto
  • Int. J. Hematol..2020 Jan;111(1):137-148. 10.1007/s12185-019-02760-5. doi: 10.1007/s12185-019-02760-5.Epub 2019-11-22.

ファバ豆由来ポリフェノール（ガテン酸、カテキン）の3T3-L1細胞株における血糖降下作用、酸化ストレス電位およびキサンチンオキシダーゼ活性の検討：分子ドッキングおよびシミュレーション研究への洞察

Investigation of hypoglycemic effects, oxidative stress potential and xanthine-oxidase activity of polyphenols (gallic acid, catechin) derived from faba bean on 3T3-L1 cell line: insights into molecular docking and simulation study.
  • Dhiraj Kumar Choudhary
  • Navaneet Chaturvedi
  • Amit Singh
  • Abha Mishra
  • Toxicol Res (Camb).2020 Jun;9(3):308-322. tfaa025. doi: 10.1093/toxres/tfaa025.Epub 2020-05-21.

エバリに関連した入院と死亡

Hospitalizations and Deaths Associated with EVALI.
  • Angela K Werner
  • Emilia H Koumans
  • Kevin Chatham-Stephens
  • Phillip P Salvatore
  • Christina Armatas
  • Paul Byers
  • Charles R Clark
  • Isaac Ghinai
  • Stacy M Holzbauer
  • Kristen A Navarette
  • Melissa L Danielson
  • Sascha Ellington
  • Erin D Moritz
  • Emily E Petersen
  • Emily A Kiernan
  • Grant T Baldwin
  • Peter Briss
  • Christopher M Jones
  • Brian A King
  • Vikram Krishnasamy
  • Dale A Rose
  • Sarah Reagan-Steiner
  • N. Engl. J. Med..2020 04;382(17):1589-1598. doi: 10.1056/NEJMoa1915314.

マイクロプレート常磁性ビーズとフィロペプチドミクスに基づいたダブルバレルクロマトグラフィー-タンデム質量分析法による細菌単離株のハイスループットなプロテオタイピング

High-throughput proteotyping of bacterial isolates by double barrel chromatography-tandem mass spectrometry based on microplate paramagnetic beads and phylopeptidomics.
  • Karim Hayoun
  • Jean-Charles Gaillard
  • Olivier Pible
  • Béatrice Alpha-Bazin
  • Jean Armengaud
  • J Proteomics.2020 Jun;226:103887. S1874-3919(20)30255-4. doi: 10.1016/j.jprot.2020.103887.Epub 2020-06-30.

選択されたイオントロピー性受容体と電圧依存性イオンチャネル。ヒト誘導多能性幹細胞(iPSC)由来侵害受容体の機能性を向上させる

Selected Ionotropic Receptors and Voltage-Gated Ion Channels: More Functional Competence for Human Induced Pluripotent Stem Cell (iPSC)-Derived Nociceptors.
  • Clemens L Schoepf
  • Maximilian Zeidler
  • Lisa Spiecker
  • Georg Kern
  • Judith Lechner
  • Kai K Kummer
  • Michaela Kress
  • Brain Sci.2020 Jun;10(6). E344. doi: 10.3390/brainsci10060344.Epub 2020-06-03.

残存大腸ポリープや線維性大腸ポリープの内視鏡治療のための機器・手技（動画あり）

Devices and techniques for endoscopic treatment of residual and fibrotic colorectal polyps (with videos).
  • Arvind J Trindade
  • Nikhil A Kumta
  • Manoop S Bhutani
  • Vinay Chandrasekhara
  • Pichamol Jirapinyo
  • Kumar Krishnan
  • Joshua Melson
  • Rahul Pannala
  • Mansour A Parsi
  • Allison R Schulman
  • Guru Trikudanathan
  • Rabindra R Watson
  • John T Maple
  • David R Lichtenstein
  • Gastrointest. Endosc..2020 Jul;S0016-5107(20)30244-3. doi: 10.1016/j.gie.2020.03.018.Epub 2020-07-05.

Canadian Longitudinal Study on Agingのベースラインデータを用いて、45～64歳の女性におけるうつ病、ホルモン療法、および更年期移行について検討した

Depression, hormone therapy, and the menopausal transition among women aged 45 to 64 years using Canadian Longitudinal Study on aging baseline data.
  • Alison K Shea
  • Nazmul Sohel
  • Anne Gilsing
  • Alexandra J Mayhew
  • Lauren E Griffith
  • Parminder Raina
  • Menopause.2020 Jul;27(7):763-770. doi: 10.1097/GME.0000000000001540.

神経集中治療におけるマイクロダイアリシスと近接拡張アッセイ技術を用いたヒト外傷性脳損傷における炎症のタンパク質バイオマーカーのモニタリング

Monitoring of Protein Biomarkers of Inflammation in Human Traumatic Brain Injury Using Microdialysis and Proximity Extension Assay Technology in Neurointensive Care.
  • Philip Dyhrfort
  • Qiujin Shen
  • Fredrik Clausen
  • Måns Thulin
  • Per Enblad
  • Masood Kamali-Moghaddam
  • Anders Lewén
  • Lars Hillered
  • J. Neurotrauma.2019 10;36(20):2872-2885. doi: 10.1089/neu.2018.6320.Epub 2019-06-17.

ダニ細胞株の実験室株と新規ノミ由来のフィールド株の単離と伝播

Isolation and Propagation of Laboratory Strains and a Novel Flea-Derived Field Strain of in Tick Cell Lines.
  • Jing Jing Khoo
  • Timothy J Kurtti
  • Nurul Aini Husin
  • Alexandra Beliavskaia
  • Fang Shiang Lim
  • Mulya Mustika Sari Zulkifli
  • Alaa M Al-Khafaji
  • Catherine Hartley
  • Alistair C Darby
  • Grant L Hughes
  • Sazaly AbuBakar
  • Benjamin L Makepeace
  • Lesley Bell-Sakyi
  • Microorganisms.2020 Jul;8(7). E988. doi: 10.3390/microorganisms8070988.Epub 2020-07-01.

EPR分光法によるヒト40Sリボソームサブユニットと短鎖RNAの相互作用の解明

Exploring the interactions of short RNAs with the human 40S ribosomal subunit near the mRNA entry site by EPR spectroscopy.
  • Alexey A Malygin
  • Olesya A Krumkacheva
  • Dmitri M Graifer
  • Ivan O Timofeev
  • Anastasia S Ochkasova
  • Maria I Meschaninova
  • Alya G Venyaminova
  • Matvey V Fedin
  • Michael Bowman
  • Galina G Karpova
  • Elena G Bagryanskaya
  • Nucleic Acids Res..2019 12;47(22):11850-11860. 5625535. doi: 10.1093/nar/gkz1039.

70歳未満の患者における修復不能な後臼蓋腱板断裂の治療のための逆全肩関節形成術と比較して、上層カプセル再建後の最短2年間の臨床成績

Minimum 2-year clinical outcomes after superior capsule reconstruction compared with reverse total shoulder arthroplasty for the treatment of irreparable posterosuperior rotator cuff tears in patients younger than 70 years.
  • Lucca Lacheta
  • Marilee P Horan
  • Brandon T Goldenberg
  • Grant J Dornan
  • Brendan Higgins
  • Peter J Millett
  • J Shoulder Elbow Surg.2020 Jun;S1058-2746(20)30303-7. doi: 10.1016/j.jse.2020.04.002.Epub 2020-06-09.

腎機能障害を有するサルコイドーシス患者における1,25ジヒドロキシビタミンDの増加

Increase of 1,25 dihydroxyvitamin D in sarcoidosis patients with renal dysfunction.
  • Naoya Toriu
  • Keiichi Sumida
  • Masahiko Oguro
  • Yoichi Oshima
  • Hiroki Mizuno
  • Eiko Hasegawa
  • Tatsuya Suwabe
  • Masahiro Kawada
  • Toshiharu Ueno
  • Noriko Hayami
  • Akinari Sekine
  • Rikako Hiramatsu
  • Masayuki Yamanouchi
  • Junichi Hoshino
  • Naoki Sawa
  • Kenmei Takaichi
  • Kenichi Ohashi
  • Keiichi Kinowaki
  • Takeshi Fujii
  • Ryosuke Date
  • Yoshifumi Ubara
  • Clin. Exp. Nephrol..2019 Oct;23(10):1202-1210. 10.1007/s10157-019-01760-3. doi: 10.1007/s10157-019-01760-3.Epub 2019-06-25.

最近発症した1型糖尿病患者における全原性脂肪組織由来の間質/幹細胞とビタミンDの補給。3ヶ月間の追跡調査パイロット試験

Allogenic Adipose Tissue-Derived Stromal/Stem Cells and Vitamin D Supplementation in Patients With Recent-Onset Type 1 Diabetes Mellitus: A 3-Month Follow-Up Pilot Study.
  • Debora B Araujo
  • Joana R Dantas
  • Karina R Silva
  • Débora L Souto
  • Maria de Fátima C Pereira
  • Jessica P Moreira
  • Ronir R Luiz
  • Cesar S Claudio-Da-Silva
  • Monica A L Gabbay
  • Sergio A Dib
  • Carlos E B Couri
  • Angelo Maiolino
  • Carmen L K Rebelatto
  • Debora R Daga
  • Alexandra C Senegaglia
  • Paulo R S Brofman
  • Leandra Santos Baptista
  • José E P Oliveira
  • Lenita Zajdenverg
  • Melanie Rodacki
  • Front Immunol.2020;11:993. doi: 10.3389/fimmu.2020.00993.Epub 2020-06-02.

マウス胚性幹細胞のRNAディープシーケンシング解析により同定された化学物質の有害性スクリーニングのためのマイクロRNAバイオマーカー

MicroRNA biomarkers for chemical hazard screening identified by RNA deep sequencing analysis in mouse embryonic stem cells.
  • Hiroshi Aoki
  • Hidenori Tani
  • Kaoru Nakamura
  • Hiroaki Sato
  • Masaki Torimura
  • Tetsuya Nakazato
  • Toxicol. Appl. Pharmacol..2020 Apr;392:114929. S0041-008X(20)30053-3. doi: 10.1016/j.taap.2020.114929.Epub 2020-02-24.

カルシウム酸。24,25-ジヒドロキシビタミンDで処理したマウスの血清中の25-ヒドロキシビタミンDの末端C24-酸化生成物および関連する中間体のin vivoでの検出および定量

Calcioic acid: In vivo detection and quantification of the terminal C24-oxidation product of 25-hydroxyvitamin D and related intermediates in serum of mice treated with 24,25-dihydroxyvitamin D.
  • Martin Kaufmann
  • Corine Martineau
  • Alice Arabian
  • Mary Traynor
  • René St-Arnaud
  • Glenville Jones
  • J. Steroid Biochem. Mol. Biol..2019 04;188:23-28. S0960-0760(18)30521-1. doi: 10.1016/j.jsbmb.2018.12.001.Epub 2018-12-13.

miR-122ノックアウトマウスにおけるRelBのアップレギュレーションは、肝臓およびマクロファージにおける炎症性ケモカイン/サイトカインレベルの上昇に寄与する

Upregulation of RelB in the miR-122 knockout mice contributes to increased levels of proinflammatory chemokines/cytokines in the liver and macrophages.
  • Ke-Hsun Hsu
  • Chin-Wen Wei
  • Yi-Ru Su
  • Tung Chou
  • Yueh-Ling Lin
  • Fu-Chen Yang
  • Ann-Ping Tsou
  • Chia-Lin Hsu
  • Ping-Hui Tseng
  • Nien-Jung Chen
  • Kuo-Shyang Jeng
  • Chuen-Miin Leu
  • Immunol. Lett..2020 Jul;226:22-30. S0165-2478(20)30346-1. doi: 10.1016/j.imlet.2020.06.015.Epub 2020-07-02.

ヒトPA200とPA200-20Sの複合体の低温電子顕微鏡構造から、プロテアソームのゲート開口とPA200の2つの開口が制御されていることが明らかになった

Cryo-EM structures of the human PA200 and PA200-20S complex reveal regulation of proteasome gate opening and two PA200 apertures.
  • Hongxin Guan
  • Youwang Wang
  • Ting Yu
  • Yini Huang
  • Mianhuan Li
  • Abdullah F U H Saeed
  • Vanja Perčulija
  • Daliang Li
  • Jia Xiao
  • Dongmei Wang
  • Ping Zhu
  • Songying Ouyang
  • PLoS Biol..2020 03;18(3):e3000654. PBIOLOGY-D-19-02639. doi: 10.1371/journal.pbio.3000654.Epub 2020-03-05.

重み付け遺伝子共発現ネットワークと競合内因性RNAネットワーク解析による変形性変形性メニスカスにおけるlncRNAとmRNAのバイオマーカーの同定

Identification of lncRNA and mRNA Biomarkers in Osteoarthritic Degenerative Meniscus by Weighted Gene Coexpression Network and Competing Endogenous RNA Network Analysis.
  • Jun Zhao
  • Yu Su
  • Jianfei Jiao
  • Zhengchun Wang
  • Xiangchun Fang
  • Xuefeng He
  • Xiaofeng Zhang
  • Zhao Liu
  • Xilin Xu
  • Biomed Res Int.2020;2020:2123787. doi: 10.1155/2020/2123787.Epub 2020-05-20.

PHBV/PLA/Col膜のデュラプラスティは、脊髄損傷ラットにおいて、NLRP3複合体とM1マクロファージの分極を抑制することで軸索再生を促進した

Duraplasty of PHBV/PLA/Col membranes promotes axonal regeneration by inhibiting NLRP3 complex and M1 macrophage polarization in rats with spinal cord injury.
  • Tengfei Zhao
  • Kan Xu
  • Qionghua Wu
  • Chenggui Wang
  • Shining Xiao
  • Heyangzi Li
  • Teng He
  • Linlin Wang
  • Fangcai Li
  • Qixin Chen
  • FASEB J..2020 Jul;doi: 10.1096/fj.202000190RR.Epub 2020-07-20.

中等期肝細胞がんの治療戦略を変えるパラダイム：アジア太平洋地域原発性肝がん専門家コンセンサス・ステートメント

A Changing Paradigm for the Treatment of Intermediate-Stage Hepatocellular Carcinoma: Asia-Pacific Primary Liver Cancer Expert Consensus Statements.
  • Masatoshi Kudo
  • Kwang-Hyub Han
  • Sheng-Long Ye
  • Jian Zhou
  • Yi-Hsiang Huang
  • Shi-Ming Lin
  • Chung-Kwe Wang
  • Masafumi Ikeda
  • Stephen Lam Chan
  • Su Pin Choo
  • Shiro Miyayama
  • Ann Lii Cheng
  • Liver Cancer.2020 Jun;9(3):245-260. lic-0009-0245. doi: 10.1159/000507370.Epub 2020-05-13.

炎症は、薬を服用していない双極性障害では、島嶼部の機能的接続性の低下と関連している

Inflammation is associated with decreased functional connectivity of insula in unmedicated bipolar disorder.
  • Pan Chen
  • Feng Chen
  • Guanmao Chen
  • Shuming Zhong
  • JiaYing Gong
  • Hui Zhong
  • Tao Ye
  • Guixian Tang
  • Jurong Wang
  • Zhenye Luo
  • Zhangzhang Qi
  • Yanbin Jia
  • Hengwen Yang
  • Zhinan Yin
  • Li Huang
  • Ying Wang
  • Brain Behav. Immun..2020 Jul;S0889-1591(20)30243-9. doi: 10.1016/j.bbi.2020.07.004.Epub 2020-07-17.

前臨床での抗血栓活性を有する高親和性の経口バイオアベイラブル大環状FXIa阻害剤の発見

Discovery of a High Affinity, Orally Bioavailable Macrocyclic FXIa Inhibitor with Antithrombotic Activity in Preclinical Species.
  • Wu Yang
  • Yufeng Wang
  • Amy Lai
  • Charles G Clark
  • James R Corte
  • Tianan Fang
  • Paul J Gilligan
  • Yoon Jeon
  • Kumar B Pabbisetty
  • Richard A Rampulla
  • Arvind Mathur
  • Mahammed Kaspady
  • Premsai Rai Neithnadka
  • Arunachalam Arumugam
  • Sivashankaran Raju
  • Karen A Rossi
  • Joseph E Myers
  • Steven Sheriff
  • Zhen Lou
  • Joanna J Zheng
  • Silvi A Chacko
  • Jeffrey M Bozarth
  • Yiming Wu
  • Earl J Crain
  • Pancras C Wong
  • Dietmar A Seiffert
  • Joseph M Luettgen
  • Patrick Y S Lam
  • Ruth R Wexler
  • William R Ewing
  • J. Med. Chem..2020 Jul;63(13):7226-7242. doi: 10.1021/acs.jmedchem.0c00464.Epub 2020-06-17.

ダール塩感受性高血圧、腎障害、Tリンパ球トランスクリプトームに対する食事の影響

Dietary Effects on Dahl Salt-Sensitive Hypertension, Renal Damage, and the T Lymphocyte Transcriptome.
  • Justine M Abais-Battad
  • Ammar J Alsheikh
  • Xiaoqing Pan
  • Daniel J Fehrenbach
  • John Henry Dasinger
  • Hayley Lund
  • Michelle L Roberts
  • Alison J Kriegel
  • Allen W Cowley
  • Srividya Kidambi
  • Theodore A Kotchen
  • Pengyuan Liu
  • Mingyu Liang
  • David L Mattson
  • Hypertension.2019 10;74(4):854-863. doi: 10.1161/HYPERTENSIONAHA.119.12927.Epub 2019-09-03.

タイで栽培された27種の植物化学物質、抗酸化物質、体外での抗アルツハイマー性の比較

Comparison of Phytochemicals, Antioxidant, and In Vitro Anti-Alzheimer Properties of Twenty-Seven spp. Cultivated in Thailand.
  • Piya Temviriyanukul
  • Varittha Sritalahareuthai
  • Kriskamol Na Jom
  • Butsara Jongruaysup
  • Somying Tabtimsri
  • Kanchana Pruesapan
  • Sirinapa Thangsiri
  • Woorawee Inthachat
  • Dalad Siriwan
  • Somsri Charoenkiatkul
  • Uthaiwan Suttisansanee
  • Molecules.2020 Jun;25(11). E2600. doi: 10.3390/molecules25112600.Epub 2020-06-03.

インプラント表面のアモルファスカーボン修飾：FAK/ERK1/2シグナル伝達経路を介して多様なバイオマテリアルの骨形成分化を促進するための一般的な戦略

Amorphous carbon modification on implant surface: a general strategy to enhance osteogenic differentiation for diverse biomaterials via FAK/ERK1/2 signaling pathways.
  • Xinran Zhang
  • Haotian Li
  • Jiaqiang Liu
  • Hui Wang
  • Wenjun Sun
  • Kaili Lin
  • Xudong Wang
  • Steve Guofang Shen
  • J Mater Chem B.2019 04;7(15):2518-2533. doi: 10.1039/c8tb02850h.Epub 2019-03-19.

非毒性の青色光（453nm）がヒト皮膚線維芽細胞の細胞抗酸化能、TGF-β1シグナル伝達、および筋線維芽細胞の筋線維形成に与える影響

The impact of non-toxic blue light (453 nm) on cellular antioxidative capacity, TGF-β1 signaling, and myofibrogenesis of human skin fibroblasts.
  • Julia M Krassovka
  • Christoph V Suschek
  • Max Prost
  • Vera Grotheer
  • Jennifer L Schiefer
  • Erhan Demir
  • Paul C Fuchs
  • Joachim Windolf
  • Ewa K Stürmer
  • Christian Opländer
  • J. Photochem. Photobiol. B, Biol..2020 Jul;209:111952. S1011-1344(20)30402-4. doi: 10.1016/j.jphotobiol.2020.111952.Epub 2020-07-06.

大脳皮質発生の奇形における標的的再配列：遺伝子型とフェノタイプの相関関係

Targeted re-sequencing in malformations of cortical development: genotype-phenotype correlations.
  • Andrea Accogli
  • Mariasavina Severino
  • Antonella Riva
  • Francesca Madia
  • Ganna Balagura
  • Michele Iacomino
  • Barbara Carlini
  • Simona Baldassari
  • Thea Giacomini
  • Carolina Croci
  • Livia Pisciotta
  • Tullio Messana
  • Antonella Boni
  • Angelo Russo
  • Leonilda Bilo
  • Rosa Tonziello
  • Antonietta Coppola
  • Alessandro Filla
  • Oriano Mecarelli
  • Rosario Casalone
  • Francesco Pisani
  • Raffaele Falsaperla
  • Silvia Marino
  • Pasquale Parisi
  • Alessandro Ferretti
  • Maurizio Elia
  • Anna Luchetti
  • Donatella Milani
  • Francesca Vanadia
  • Laura Silvestri
  • Erika Rebessi
  • Eliana Parente
  • Giampaolo Vatti
  • Maria Margherita Mancardi
  • Lino Nobili
  • Valeria Capra
  • Vincenzo Salpietro
  • Pasquale Striano
  • Federico Zara
  • Seizure.2020 Jun;80:145-152. S1059-1311(20)30153-9. doi: 10.1016/j.seizure.2020.05.023.Epub 2020-06-03.

ワルデンストロームマクログロブリン血症患者を対象としたイブルチニブ単剤療法の奏効率と生存率 臨床試験のオンとオフの結果について

Response and Survival Outcomes to Ibrutinib Monotherapy for Patients With Waldenström Macroglobulinemia on and off Clinical Trials.
  • Jorge J Castillo
  • Joshua N Gustine
  • Kirsten Meid
  • Catherine A Flynn
  • Maria G Demos
  • Maria L Guerrera
  • Cristina Jimenez
  • Amanda Kofides
  • Xia Liu
  • Manit Munshi
  • Nicholas Tsakmaklis
  • Christopher J Patterson
  • Lian Xu
  • Guang Yang
  • Zachary R Hunter
  • Steven P Treon
  • Hemasphere.2020 Jun;4(3):e363. HemaSphere-2019-0201. doi: 10.1097/HS9.0000000000000363.Epub 2020-05-21.

アフリカトリパノソーマの成長を阻害し、発生制御遺伝子の転写レベルに影響を与える臨床的に承認された低分子の同定

Identification of clinically approved small molecules that inhibit growth and affect transcript levels of developmentally regulated genes in the African trypanosome.
  • Madison Elle Walsh
  • Eleanor Mary Naudzius
  • Savanah Jessica Diaz
  • Theodore William Wismar
  • Mikhail Martchenko Shilman
  • Danae Schulz
  • PLoS Negl Trop Dis.2020 03;14(3):e0007790. PNTD-D-19-01546. doi: 10.1371/journal.pntd.0007790.Epub 2020-03-13.

二硫化モリブデンをポリエーテルエーテルケトンに組み込むことで、機械的性能、トライボロジー性能、細胞適合性を向上させた人工関節用のバイオコンポジットが得られた

Incorporation of molybdenum disulfide into polyetheretherketone creating biocomposites with improved mechanical, tribological performances and cytocompatibility for artificial joints applications.
  • Xinke Lv
  • Xuehong Wang
  • Songchao Tang
  • Dongliang Wang
  • Lili Yang
  • Axiang He
  • Tingting Tang
  • Jie Wei
  • Colloids Surf B Biointerfaces.2020 May;189:110819. S0927-7765(20)30049-7. doi: 10.1016/j.colsurfb.2020.110819.Epub 2020-01-21.

下肢バイパスのための強化された回復プログラムの実施

Implementation of an Enhanced Recovery Program for Lower Extremity Bypass.
  • Adam Witcher
  • John Axley
  • Zdenek Novak
  • Maria Laygo-Prickett
  • Meredith Guthrie
  • Anisa Xhaja
  • Daniel I Chu
  • S Danielle Brokus
  • Emily L Spangler
  • Marc A Passman
  • Katharine L McGinigle
  • Benjamin J Pearce
  • Ryne Schlitz
  • Roland T Short
  • Jeffrey W Simmons
  • Richard C Cross
  • Graeme E McFarland
  • Adam W Beck
  • J. Vasc. Surg..2020 Jul;S0741-5214(20)31581-0. doi: 10.1016/j.jvs.2020.06.106.Epub 2020-07-15.

エレクトロスピンPCLベースのナノファイバー <i>Arrabidaea chica</i> Verlot - <i>Pterodon pubescens</i> Benth loaded:線維芽細胞形成の相乗効果

Electrospun PCL-based nanofibers <i>Arrabidaea chica</i> Verlot - <i>Pterodon pubescens</i> Benth loaded: synergic effect in fibroblast formation.
  • Taís Helena Costa Salles
  • Fabiana Volpe-Zanutto
  • Ilza Maria de Oliveira Sousa
  • Daisy Machado
  • Ana Caroline Zanatta
  • Wagner Vilegas
  • Marcelo Lancellotti
  • Mary Ann Foglio
  • Marcos Akira d'Ávila
  • Biomed Mater.2020 Jun;doi: 10.1088/1748-605X/ab9bb1.Epub 2020-06-11.

血漿脂質バイオマーカー解析により、血管性痴呆における脂質の変化が明らかになった

Plasma lipidomic biomarker analysis reveals distinct lipid changes in vascular dementia.
  • Yue Liu
  • Daniel K Y Chan
  • Anbupalam Thalamuthu
  • Wei Wen
  • Jiyang Jiang
  • Matthew Paradise
  • Teresa Lee
  • John Crawford
  • Matthew Wai Kin Wong
  • Ying Hua Xu
  • Anne Poljak
  • Russell Pickford
  • Perminder S Sachdev
  • Nady Braidy
  • Comput Struct Biotechnol J.2020;18:1613-1624. S2001-0370(20)30289-0. doi: 10.1016/j.csbj.2020.06.001.Epub 2020-06-09.

保存されていないヒト脂肪lincRNAの探索により、脂肪細胞の代謝を制御する役割が明らかになった

Interrogation of nonconserved human adipose lincRNAs identifies a regulatory role of in adipocyte metabolism.
  • Xuan Zhang
  • Chenyi Xue
  • Jennie Lin
  • Jane F Ferguson
  • Amber Weiner
  • Wen Liu
  • Yumiao Han
  • Christine Hinkle
  • Wenjun Li
  • Hongfeng Jiang
  • Sager Gosai
  • Melanie Hachet
  • Benjamin A Garcia
  • Brian D Gregory
  • Raymond E Soccio
  • John B Hogenesch
  • Patrick Seale
  • Mingyao Li
  • Muredach P Reilly
  • Sci Transl Med.2018 06;10(446). eaar5987. doi: 10.1126/scitranslmed.aar5987.

炎症性腸疾患の若年患者における仙腸炎の徴候検出における磁気共鳴腸管造影検査の有用性

Usefulness of magnetic resonance enterography in detecting signs of sacroiliitis in young patients with inflammatory bowel disease.
  • Teresa Giani
  • Azzurra Bernardini
  • Massimo Basile
  • Marco Di Maurizo
  • Anna Perrone
  • Sara Renzo
  • Viola Filistrucchi
  • Rolando Cimaz
  • Paolo Lionetti
  • Pediatr Rheumatol Online J.2020 Jun;18(1):42. 10.1186/s12969-020-00433-w. doi: 10.1186/s12969-020-00433-w.Epub 2020-06-03.

天然着色料の分析と生物学的活性。オプンティア種の生物多様性を探索するための分子マーカーとの関連付け

Natural colourants analysis and biological activities. Association to molecular markers to explore the biodiversity of Opuntia species.
  • Nidhal Salem
  • Myriam Lamine
  • Bilel Damergi
  • Fatma Ezahra
  • Nedia Feres
  • Selim Jallouli
  • Majdi Hammami
  • Saber Khammassi
  • Sawsen Selmi
  • Salem Elkahoui
  • Ferid Limam
  • Olfa Tabben
  • Phytochem Anal.2020 Jun;doi: 10.1002/pca.2954.Epub 2020-06-16.

アカラシアにおける腹腔鏡下ヘラーミオトミーまたは空気圧拡張術：少なくとも10年以上の追跡調査を行ったプロスペクティブ無作為化試験の結果

Laparoscopic Heller myotomy or pneumatic dilatation in achalasia: results of a prospective, randomized study with at least a decade of follow-up.
  • Ehsan Sediqi
  • Alexandros Tsoposidis
  • Ville Wallenius
  • Hans Axelsson
  • Jan Persson
  • Erik Johnsson
  • Lars Lundell
  • Srdjan Kostic
  • Surg Endosc.2020 Apr;10.1007/s00464-020-07541-4. doi: 10.1007/s00464-020-07541-4.Epub 2020-04-17.