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日本語AIでPubMedを検索

日本語AIでPubMedを検索

PubMedの提供する医学論文データベースを日本語で検索できます。AI(Deep Learning)を活用した機械翻訳エンジンにより、精度高く日本語へ翻訳された論文をご参照いただけます。

みんなが読んでいる論文

乳房病理組織標本の一次診断のためのデジタル病理学:デジタル病理学の検証とトレーニングに関する革新的な検証とコンコーダンス研究

Digital pathology for the primary diagnosis of breast histopathological specimens: an innovative validation and concordance study on digital pathology validation and training.
  • Bethany Jill Williams
  • Andrew Hanby
  • Rebecca Millican-Slater
  • Anju Nijhawan
  • Eldo Verghese
  • Darren Treanor
  • Histopathology.2018 Mar;72(4):662-671. doi: 10.1111/his.13403.Epub 2017-12-11.

インドにおける精神科研修の評価。インド精神医学会の研究・教育・研修財団の支援のもと、若手精神科医を対象とした調査

Evaluation of psychiatry training in India: A survey of young psychiatrists under the aegis of research, education, and training foundation of Indian Psychiatric Society.
  • Sandeep Grover
  • Swapnajeet Sahoo
  • Balachander Srinivas
  • Adarsh Tripathi
  • Ajit Avasthi
  • Indian J Psychiatry.2018 Oct-Dec;60(4):445-460. IJPsy-60-445. doi: 10.4103/psychiatry.IndianJPsychiatry_334_18.

ヘミラビール(κ2-C,S)-チオエーテル官能化NHC配位子を有するハーフサンドイッチ型ルテニウム錯体の合成、特性評価、触媒作用及び生物学的応用

Synthesis, characterization, catalytic and biological application of half-sandwich ruthenium complexes bearing hemilabile (κ2-C,S)-thioether-functionalised NHC ligands.
  • Weiguang Chen
  • Julien Egly
  • Amalia I Poblador-Bahamonde
  • Aline Maisse-Francois
  • Stéphane Bellemin-Laponnaz
  • Thierry Achard
  • Dalton Trans.2020 Mar;49(10):3243-3252. doi: 10.1039/c9dt04825a.Epub 2020-02-25.

グラム陰性およびグラム陽性細菌に対するフルオプシンCの作用の標的の決定

Determining the Targets of Fluopsin C Action on Gram-Negative and Gram-Positive Bacteria.
  • Miguel Octavio Pérez Navarro
  • Guilherme Dilarri
  • Ane Stefano Simionato
  • Kathlen Grzegorczyk
  • Mickely Liuti Dealis
  • Barbara Gionco Cano
  • André Riedi Barazetti
  • Leandro Afonso
  • Andreas Lazaros Chryssafidis
  • Henrique Ferreira
  • Galdino Andrade
  • Front Microbiol.2020;11:1076. doi: 10.3389/fmicb.2020.01076.Epub 2020-06-04.

リファキシミンは、腸内細菌叢の多様性に影響を与えることなく、肝性脳症やエンドトキシン血症を改善します

Rifaximin ameliorates hepatic encephalopathy and endotoxemia without affecting the gut microbiome diversity.
  • Kosuke Kaji
  • Hiroaki Takaya
  • Soichiro Saikawa
  • Masanori Furukawa
  • Shinya Sato
  • Hideto Kawaratani
  • Mitsuteru Kitade
  • Kei Moriya
  • Tadashi Namisaki
  • Takemi Akahane
  • Akira Mitoro
  • Hitoshi Yoshiji
  • World J. Gastroenterol..2017 Dec;23(47):8355-8366. doi: 10.3748/wjg.v23.i47.8355.

ミクログリアはアルコール依存性マウスにおける飲酒のエスカレーションを制御する:ゲノムとシナプスのドライバー

Microglia Control Escalation of Drinking in Alcohol-Dependent Mice: Genomic and Synaptic Drivers.
  • Anna S Warden
  • Sarah A Wolfe
  • Sophia Khom
  • Florence P Varodayan
  • Reesha R Patel
  • Michael Q Steinman
  • Michal Bajo
  • Sarah E Montgomery
  • Roman Vlkolinsky
  • Tali Nadav
  • Ilham Polis
  • Amanda J Roberts
  • R Dayne Mayfield
  • R Adron Harris
  • Marisa Roberto
  • Biol. Psychiatry.2020 May;S0006-3223(20)31598-5. doi: 10.1016/j.biopsych.2020.05.011.Epub 2020-05-19.

多環芳香族炭化水素汚染土壌のファイトレメディエーションを促進するための白腐れ菌(Crucibulum laeve)の接種法の開発

Enhancing Salix viminalis L.-mediated phytoremediation of polycyclic aromatic hydrocarbon-contaminated soil by inoculation with Crucibulum laeve (white-rot fungus).
  • Xiaodong Ma
  • Xia Li
  • Junxiang Liu
  • Yunhe Cheng
  • Feifei Zhai
  • Zhenyuan Sun
  • Lei Han
  • Environ Sci Pollut Res Int.2020 Jul;10.1007/s11356-020-10125-3. doi: 10.1007/s11356-020-10125-3.Epub 2020-07-17.

ミトコンドリアターゲティング農薬のパネルを用いたHepG2およびRPTEC/TERT1細胞におけるミトコンドリア呼吸抑制のマルチパラメトリック評価

Multiparametric assessment of mitochondrial respiratory inhibition in HepG2 and RPTEC/TERT1 cells using a panel of mitochondrial targeting agrochemicals.
  • Wanda van der Stel
  • Giada Carta
  • Julie Eakins
  • Salihanur Darici
  • Johannes Delp
  • Anna Forsby
  • Susanne Hougaard Bennekou
  • Iain Gardner
  • Marcel Leist
  • Erik H J Danen
  • Paul Walker
  • Bob van de Water
  • Paul Jennings
  • Arch. Toxicol..2020 Jul;10.1007/s00204-020-02792-5. doi: 10.1007/s00204-020-02792-5.Epub 2020-07-18.

放射線性口腔乾燥症に対する有効単核細胞(E-MNC)を用いた細胞療法の第1相臨床試験(ヒト初)(放射線性口腔乾燥症に対するE-MNC療法に関するFIH試験)

Phase 1 clinical study of cell therapy with effective-mononuclear cells (E-MNC) for radiogenic xerostomia (first-in-human study) (FIH study on E-MNC therapy for radiogenic xerostomia).
  • Yoshinori Sumita
  • Naoki Iwamoto
  • Makoto Seki
  • Takako Yoshida
  • Ryo Honma
  • Mayumi Iwatake
  • Seigo Ohba
  • I Takashi
  • Yuka Hotokezaka
  • Hiroshi Harada
  • Shinichiro Kuroshima
  • Kazuhiro Nagai
  • Takayuki Asahara
  • I Atsushi Kawakam
  • Izumi Asahina
  • Medicine (Baltimore).2020 Jun;99(26):e20788. 00005792-202006260-00034. doi: 10.1097/MD.0000000000020788.

グルタチオンペルオキシダーゼファミリー。グルタチオンペルオキシダーゼファミリー:これらの抗酸化酵素の比較解析と金属や酸化剤に対する遺伝子発現の違い

Glutathione Peroxidase Family: A Comparative Analysis of These Antioxidant Enzymes and Differential Gene Expression to Metals and Oxidizing Agents.
  • Liliana L Cubas-Gaona
  • Patricia de Francisco
  • Ana Martín-González
  • Juan Carlos Gutiérrez
  • Microorganisms.2020 Jul;8(7). E1008. doi: 10.3390/microorganisms8071008.Epub 2020-07-05.

V2+V3特発性三叉神経痛の治療には、半月状神経節ラジオ波熱凝固術と比較して、ロータンドゥム孔、卵巣孔を介した末梢神経ラジオ波熱凝固術を用いた

The treatment of V2 + V3 idiopathic trigeminal neuralgia using peripheral nerve radiofrequency thermocoagulation via the foramen rotundum and foramen ovale compared with semilunar ganglion radiofrequency thermocoagulation.
  • Fei Zeng
  • Mengye Zhu
  • Quan Wan
  • Yi Yan
  • Changxi Li
  • Yong Zhang
  • Clin Neurol Neurosurg.2020 Jun;196:106025. S0303-8467(20)30368-1. doi: 10.1016/j.clineuro.2020.106025.Epub 2020-06-17.

ロングノンコーディングRNA SNHG12は、腎細胞癌におけるCDCA3のアップレギュレーションにより、腫瘍の進行とスニチニブ抵抗性を促進する

Long noncoding RNA SNHG12 promotes tumour progression and sunitinib resistance by upregulating CDCA3 in renal cell carcinoma.
  • Yuenan Liu
  • Gong Cheng
  • Ziwei Huang
  • Lin Bao
  • Jingchong Liu
  • Cheng Wang
  • Zhiyong Xiong
  • Lijie Zhou
  • Tianbo Xu
  • Di Liu
  • Hongmei Yang
  • Ke Chen
  • Xiaoping Zhang
  • Cell Death Dis.2020 Jul;11(7):515. 10.1038/s41419-020-2713-8. doi: 10.1038/s41419-020-2713-8.Epub 2020-07-08.

臨床分離株における低レベルポリミキシン耐性検出の難しさ:Rapid Polymyxin NPテスト、Colispotテスト、SuperPolymyxin培地の評価

Difficulty in detecting low levels of polymyxin resistance in clinical isolates: evaluation of Rapid Polymyxin NP test, Colispot Test and SuperPolymyxin medium.
  • O C Conceição-Neto
  • B S da Costa
  • L S Pontes
  • I C O Santos
  • M C Silveira
  • J R Cordeiro-Moura
  • N F Pereira
  • C B Tavares-Teixeira
  • R C Picão
  • C M Rocha-de-Souza
  • A P D Carvalho-Assef
  • New Microbes New Infect.2020 Jul;36:100722. S2052-2975(20)30074-3. doi: 10.1016/j.nmni.2020.100722.Epub 2020-06-25.

Frontline Science.TNF-αとGM-CSF1のプライミングは、Ras、PI3K-γ、好中球プロ炎症反応の活性化を促進するSOS1/2の役割を増大させる

Frontline Science: TNF-α and GM-CSF1 priming augments the role of SOS1/2 in driving activation of Ras, PI3K-γ, and neutrophil proinflammatory responses.
  • Sabine Suire
  • Fernando C Baltanas
  • Anne Segonds-Pichon
  • Keith Davidson
  • Eugenio Santos
  • Phillip T Hawkins
  • Len R Stephens
  • J. Leukoc. Biol..2019 10;106(4):815-822. doi: 10.1002/JLB.2HI0918-359RR.Epub 2019-02-05.

高リスクの心臓外科手術における死亡率を予測するための加算ロジスティック・ヨーロッパ心臓手術リスクシステム(EuroSCORE)とEuroSCORE 2の比較

Comparison of the additive, logistic european system for cardiac operative risk (EuroSCORE) with the EuroSCORE 2 to predict mortality in high-risk cardiac surgery.
  • Laura Guillet
  • Pierre H Moury
  • Damien Bedague
  • Michel Durand
  • Cécile Martin
  • Jean F Payen
  • Olivier Chavanon
  • Pierre Albaladejo
  • Ann Card Anaesth.2020 Jul-Sep;23(3):277-282. AnnCardAnaesth_2020_23_3_277_290043. doi: 10.4103/aca.ACA_209_18.

肝臓でのブドウ糖の利用率が低いと、外因性高コレステロール血症ラットの食事誘発性高コレステロール血症を引き起こす

Low utilization of glucose in the liver causes diet-induced hypercholesterolemia in exogenously hypercholesterolemic rats.
  • Yasutake Tanaka
  • Masahiro Ono
  • Motonori Miyago
  • Takahisa Suzuki
  • Yurika Miyazaki
  • Michio Kawano
  • Makoto Asahina
  • Bungo Shirouchi
  • Katsumi Imaizumi
  • Masao Sato
  • PLoS ONE.2020;15(3):e0229669. PONE-D-19-24869. doi: 10.1371/journal.pone.0229669.Epub 2020-03-12.

1 日 1 回経口投与の新規 5-リポオキシゲナーゼ活性化蛋白質阻害薬 AZD5718 の初期臨床経験

Initial Clinical Experience with AZD5718, a Novel Once Daily Oral 5-Lipoxygenase Activating Protein Inhibitor.
  • Hans Ericsson
  • Karin Nelander
  • Maria Lagerstrom-Fermer
  • Clare Balendran
  • Maria Bhat
  • Ligia Chialda
  • Li-Ming Gan
  • Maria Heijer
  • Magnus Kjaer
  • John Lambert
  • Eva-Lotte Lindstedt
  • Gun-Britt Forsberg
  • Carl Whatling
  • Stanko Skrtic
  • Clin Transl Sci.2018 05;11(3):330-338. doi: 10.1111/cts.12546.Epub 2018-03-08.

小さなカエルが長い道のりを飛躍させる:小さな東洋のカエル属(両生類:Microhylidae)で発見されたインド亜大陸の複合的な植民地化

A little frog leaps a long way: compounded colonizations of the Indian Subcontinent discovered in the tiny Oriental frog genus (Amphibia: Microhylidae).
  • Vladislav A Gorin
  • Evgeniya N Solovyeva
  • Mahmudul Hasan
  • Hisanori Okamiya
  • D M S Suranjan Karunarathna
  • Parinya Pawangkhanant
  • Anslem de Silva
  • Watinee Juthong
  • Konstantin D Milto
  • Luan Thanh Nguyen
  • Chatmongkon Suwannapoom
  • Alexander Haas
  • David P Bickford
  • Indraneil Das
  • Nikolay A Poyarkov
  • PeerJ.2020;8:e9411. 9411. doi: 10.7717/peerj.9411.Epub 2020-07-03.

可溶性血管内皮増殖因子受容体-1に対する内皮細胞の接着は、細胞の動態と血管新生の表現型を誘発する

Endothelial cell adhesion to soluble vascular endothelial growth factor receptor-1 triggers a cell dynamic and angiogenic phenotype.
  • Angela Orecchia
  • Amel Mettouchi
  • Paolo Uva
  • Glenn C Simon
  • Diego Arcelli
  • Simona Avitabile
  • Gianluca Ragone
  • Guerrino Meneguzzi
  • Karl H Pfenninger
  • Giovanna Zambruno
  • Cristina Maria Failla
  • FASEB J..2014 Feb;28(2):692-704. fj.12-225771. doi: 10.1096/fj.12-225771.Epub 2013-10-30.

血清性抗リン脂質症候群の診断におけるアネキシンA5抵抗性と非基準抗体の意義

Annexin-A5 resistance and non-criteria antibodies for the diagnosis of seronegative antiphospholipid syndrome.
  • Théo Ghelfenstein Ferreira
  • François Delhommeau
  • Catherine Johanet
  • Grigorios Gerotziafas
  • Marie Bornes
  • Jonathan Cohen
  • Gilles Kayem
  • Olivier Fain
  • Virginie Planche
  • Arsene Mékinian
  • Clin. Rheumatol..2020 Apr;39(4):1167-1171. 10.1007/s10067-019-04915-5. doi: 10.1007/s10067-019-04915-5.Epub 2020-01-10.

胎児の心室セプタムが無傷の肺動脈性心房症に対する胎児心臓インターベンション:国際胎児心臓インターベンション・レジストリ(IFCIR)

Fetal Cardiac Intervention for Pulmonary Atresia with Intact Ventricular Septum: International Fetal Cardiac Intervention Registry.
  • Whitnee J Hogan
  • Sofia Grinenco
  • Aimee Armstrong
  • Roland Devlieger
  • Joanna Dangel
  • Queralt Ferrer
  • Michele Frommelt
  • Alberto Galindo
  • Helena Gardiner
  • Sarah Gelehrter
  • Ulrike Herberg
  • Lisa Howley
  • Edgar Jaeggi
  • Joana Miranda
  • Shaine A Morris
  • Dick Oepkes
  • Simone Pedra
  • Renuka Peterson
  • Gary Sholler
  • John Simpson
  • James Strainic
  • Trisha V Vigneswarran
  • Annette Wacker-Gussmann
  • Anita J Moon-Grady
  • Fetal. Diagn. Ther..2020 Jul;:1-9. 000508045. doi: 10.1159/000508045.Epub 2020-07-07.

アジアのびらん性食道炎患者を対象に、ランソプラゾールと比較したフォノプラザンの有効性と安全性を評価する第Ⅲ相無作為化二重盲検多施設共同試験

Phase III, randomised, double-blind, multicentre study to evaluate the efficacy and safety of vonoprazan compared with lansoprazole in Asian patients with erosive oesophagitis.
  • Yinglian Xiao
  • Shutian Zhang
  • Ning Dai
  • Guijun Fei
  • Khean-Lee Goh
  • Hoon Jai Chun
  • Bor-Shyang Sheu
  • Chui Fung Chong
  • Nobuo Funao
  • Wen Zhou
  • Minhu Chen
  • Gut.2020 02;69(2):224-230. gutjnl-2019-318365. doi: 10.1136/gutjnl-2019-318365.Epub 2019-08-13.

ゲノムワイドなスクリーニングにより、女性の性器管のコロニー化とウイルス性を促進するA群連鎖球菌表面タンパク質が同定された

Genome-Wide Screens Identify Group A Streptococcus Surface Proteins Promoting Female Genital Tract Colonization and Virulence.
  • Luchang Zhu
  • Randall J Olsen
  • Stephen B Beres
  • Matthew Ojeda Saavedra
  • Samantha L Kubiak
  • Concepcion C Cantu
  • Leslie Jenkins
  • Prasanti Yerramilli
  • Layne Pruitt
  • Amelia R L Charbonneau
  • Andrew S Waller
  • James M Musser
  • Am. J. Pathol..2020 04;190(4):862-873. S0002-9440(20)30018-3. doi: 10.1016/j.ajpath.2019.12.003.Epub 2020-03-19.

閉経後出血を伴う女性における主観的パターン認識による子宮内膜癌の超音波診断:プロスペクティブな評価者間の一致度と信頼性に関する研究

Ultrasound diagnosis of endometrial cancer by subjective pattern recognition in women with postmenopausal bleeding: a prospective inter-rater agreement and reliability study.
  • M Wong
  • N Thanatsis
  • T Amin
  • E Bean
  • K Madhvani
  • D Jurkovic
  • Ultrasound Obstet Gynecol.2020 Jul;doi: 10.1002/uog.22141.Epub 2020-07-04.

ヒト胚性幹細胞由来の筋原性前駆細胞から設計された骨格筋構築物は、EGM-2サプリメントを含む培地中で分化したときに拡張された収縮力を展示しています

Skeletal Muscle Constructs Engineered from Human Embryonic Stem Cell Derived Myogenic Progenitors Exhibit Enhanced Contractile Forces When Differentiated in a Medium Containing EGM-2 Supplements.
  • Bin Xu
  • Mengen Zhang
  • Rita C R Perlingeiro
  • Wei Shen
  • Adv Biosyst.2019 Dec;3(12):e1900005. doi: 10.1002/adbi.201900005.Epub 2019-11-04.

メチオニン残基の酸化は、高閾値熱感受性イオンチャネルTRPV2を活性化する

Oxidation of methionine residues activates the high-threshold heat-sensitive ion channel TRPV2.
  • Tabea C Fricke
  • Frank Echtermeyer
  • Johannes Zielke
  • Jeanne de la Roche
  • Milos R Filipovic
  • Stéphane Claverol
  • Christine Herzog
  • Makoto Tominaga
  • Ruth A Pumroy
  • Vera Y Moiseenkova-Bell
  • Peter M Zygmunt
  • Andreas Leffler
  • Mirjam J Eberhardt
  • Proc. Natl. Acad. Sci. U.S.A..2019 11;116(48):24359-24365. 1904332116. doi: 10.1073/pnas.1904332116.Epub 2019-11-12.

大規模なセーフティネット病院における非定型腺細胞の割合の高さは、疾患の発生率の高さと相関するか?

Do High Rates of Atypical Glandular Cells Correlate With Higher Incidence of Disease in a Large Safety Net Hospital.
  • Theresa Kuhn
  • Catherine Finneran
  • Adrian Kohut
  • Emily Wang
  • George Birdsong
  • Uma Krishnamurti
  • Marina Mosunjac
  • Talaat Tadros
  • Gabriela Oprea
  • Vaidehi Avadhani
  • Shae Boguslawski
  • Samantha Karlow
  • Peter Schnatz
  • Namita Khanna
  • Lisa Flowers
  • J Low Genit Tract Dis.2020 Jun;doi: 10.1097/LGT.0000000000000556.Epub 2020-06-17.

慢性ストレス下での神経血管カップリングはGABA作動性神経細胞間葉系活動の変化によって変化する.

Neurovascular Coupling under Chronic Stress Is Modified by Altered GABAergic Interneuron Activity.
  • Kayoung Han
  • Jiwoong Min
  • Myunghee Lee
  • Bok-Man Kang
  • Taeyoung Park
  • Junghyun Hahn
  • Jaeseung Yei
  • Juheon Lee
  • Junsung Woo
  • C Justin Lee
  • Seong-Gi Kim
  • Minah Suh
  • J. Neurosci..2019 12;39(50):10081-10095. JNEUROSCI.1357-19.2019. doi: 10.1523/JNEUROSCI.1357-19.2019.Epub 2019-10-31.

自然細胞死と細菌性病害抵抗性の向上を示すイネ病巣擬態変異体oshpl3の特性と遺伝学的解析

Characterization and genetic analysis of the oshpl3 rice lesion mimic mutant showing spontaneous cell death and enhanced bacterial blight resistance.
  • Ranran Tu
  • Hong Wang
  • Qunen Liu
  • Dongfei Wang
  • Xingpeng Zhou
  • Peng Xu
  • Yinxing Zhang
  • Weixun Wu
  • Daibo Chen
  • Liyong Cao
  • Shihua Cheng
  • Xihong Shen
  • Plant Physiol. Biochem..2020 May;154:94-104. S0981-9428(20)30215-1. doi: 10.1016/j.plaphy.2020.05.001.Epub 2020-05-08.

ツバ・メラノスポラム(Tuber melanosporum)とツバ・インディカム(Tuber indicum)による植民地化は、根圏におけるマツ・アーマンディ(Pinus armandii)の生育とphoDアルカリホスファターゼをコードする細菌群集に影響を与えることがわかった

Colonization by Tuber melanosporum and Tuber indicum affects the growth of Pinus armandii and phoD alkaline phosphatase encoding bacterial community in the rhizosphere.
  • Xiaoping Zhang
  • Xiaolin Li
  • Lei Ye
  • Yue Huang
  • Zongjing Kang
  • Bo Zhang
  • Xiaoping Zhang
  • Microbiol. Res..2020 Jun;239:126520. S0944-5013(20)30388-8. doi: 10.1016/j.micres.2020.126520.Epub 2020-06-03.

古代のゲノムから明らかになった中国のカシミア生産ヤギの進化の歴史と起源

Ancient Genomes Reveal the Evolutionary History and Origin of Cashmere-Producing Goats in China.
  • Yudong Cai
  • Weiwei Fu
  • Dawei Cai
  • Rasmus Heller
  • Zhuqing Zheng
  • Jia Wen
  • Hui Li
  • Xiaolong Wang
  • Akil Alshawi
  • Zhouyong Sun
  • Siqi Zhu
  • Juan Wang
  • Miaomiao Yang
  • Songmei Hu
  • Yan Li
  • Zhirui Yang
  • Mian Gong
  • Yunan Hou
  • Tianming Lan
  • Kui Wu
  • Yulin Chen
  • Yu Jiang
  • Xihong Wang
  • Mol. Biol. Evol..2020 Jul;37(7):2099-2109. 5824306. doi: 10.1093/molbev/msaa103.

臍帯血移植患者を対象とした移植前播種性フザリヌス菌症の高用量リポソーマルアムホテリシンB投与による治療に成功した

[Successful treatment of pre-engraftment disseminated fusariosis with high-dose liposomal amphotericin B in a cord blood transplant recipient].
  • Yasuhiko Harada
  • Makoto Murata
  • Akane Matsumoto
  • Daizo Kato
  • Tetsuya Yagi
  • Takashi Yaguchi
  • Takenori Yoshikawa
  • Takuya Takeichi
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肺癌に対する新規EGFR L858Rキナーゼ阻害剤としてのルテオリン-7-グルコシドとエピカテキンガレートの同定。ドッキングとシミュレーションに基づく研究

Identification of luteolin -7-glucoside and epicatechin gallate from , as novel EGFR L858R kinase inhibitors against lung cancer: Docking and simulation-based study.
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外傷と出血性ショックで肺組織内の5-リポキシゲナーゼと5-リポキシゲナーゼ活性化蛋白質の分子会合が活性化されることを明らかにした

Trauma and hemorrhagic shock activate molecular association of 5-lipoxygenase and 5-lipoxygenase-Activating protein in lung tissue.
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国の栄養研究の強化:新たに調整された連邦政府の研究努力と権限のための根拠と選択肢

Strengthening national nutrition research: rationale and options for a new coordinated federal research effort and authority.
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アンデスの深層人口史の古生物学的再構築

A Paleogenomic Reconstruction of the Deep Population History of the Andes.
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DNA二本鎖切断部の機能的転写プロモーターがダメージ応答因子のRNA駆動型相分離を媒介している

Functional transcription promoters at DNA double-strand breaks mediate RNA-driven phase separation of damage-response factors.
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アリールメチルイソシアニドおよびアリールメチルアミンとキサンタートエステルの反応:カルバモチオエートの意外な合成法を提案した

The reaction of arylmethyl isocyanides and arylmethylamines with xanthate esters: a facile and unexpected synthesis of carbamothioates.
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繁殖期の開始時に測定された窒素および硫黄の再固定化関連パラメータは、Nおよび/またはS制限供給下で栽培されたナタネ(Brassica napus L.)において、NおよびS施肥を調整するための早期指標となるか?

Do nitrogen- and sulphur-remobilization-related parameters measured at the onset of the reproductive stage provide early indicators to adjust N and S fertilization in oilseed rape (Brassica napus L.) grown under N- and/or S-limiting supplies?
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Remind Me To Remember.認知症と軽度の認知障害を持つ高齢者のための新しいスマートフォンリマインダーアプリケーションのパイロット研究

Remind Me To Remember: A pilot study of a novel smartphone reminder application for older adults with dementia and mild cognitive impairment.
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卵母細胞の体外成熟期におけるニコチンアミドの補給は着床前胚の発達能力を向上させる。SIRT1/AKTシグナリングとの潜在的なリンク

Nicotinamide Supplementation during the In Vitro Maturation of Oocytes Improves the Developmental Competence of Preimplantation Embryos: Potential Link to SIRT1/AKT Signaling.
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引退した男性エリート・アマチュアレベルのラグビーコードアスリートと非接触アスリートにおけるスポーツ関連の累積傷害と長期的な影響。レトロスペクティブ研究

Cumulative Sport-Related Injuries and Longer Term Impact in Retired Male Elite- and Amateur-Level Rugby Code Athletes and Non-contact Athletes: A Retrospective Study.
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パキスタン産Fabricius属(Lepidoptera: Lepidoptera: Noctuidae: Plusiinae)の最初の記録と分類学的記述

First record and taxonomic description of the genus (Fabricius) (Lepidoptera: Noctuidae: Plusiinae) from Pakistan.
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  • Imran Bodlah
  • Khalid Naveed
  • Tahammal Hussain
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  • Khalid Ali Khan
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健康なボランティアと再発・難治性急性骨髄性白血病患者におけるキザルチニブの集団薬物動態解析

Population Pharmacokinetic Analysis of Quizartinib in Healthy Volunteers and Patients With Relapsed/Refractory Acute Myeloid Leukemia.
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  • David Jaworowicz
  • Hannah Huang
  • Jill Fiedler-Kelly
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  • Siddhartha Ganguly
  • Samer Khaled
  • Alwin Krämer
  • Mark Levis
  • Giovanni Martinelli
  • Alexander Perl
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サンパウロ州(ブラジル)で分離された臨床株をMALDI-TOF MSおよび分子生物学的手法で同定した初の包括的報告書

First Comprehensive Report of Clinical Strains Isolated in the State of Sao Paulo (Brazil) and Identified by MALDI-TOF MS and Molecular Biology.
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  • Ludmilla Tonani Carvalho
  • Marcia de Souza Carvalho Melhem
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  • Maria Emilia Nadaletto Bonifácio da Silva
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  • Marcia Regina von Zeska Kress
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慢性閉塞性肺疾患における LAMA/LABA 合剤併用療法の有効性と安全性。直接的および間接的な治療比較の系統的レビュー

Efficacy and Safety of LAMA/LABA Fixed-Dose Combination Therapies in Chronic Obstructive Pulmonary Disease: A Systematic Review of Direct and Indirect Treatment Comparisons.
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  • Kevin Gruffydd-Jones
  • Mousumi Biswas
  • Deniz Guranlioglu
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野生型マウスとCdk5-/-マウスの比較リン酸化プロテオミクスによる脳内新規Cdk5基質の探索

Searching for novel Cdk5 substrates in brain by comparative phosphoproteomics of wild type and Cdk5-/- mice.
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Fasが媒介する好中球のアポトーシスは、Bid、Bak、およびBaxによって促進され、Bcl-2およびMcl-1によって阻害される

Fas-mediated neutrophil apoptosis is accelerated by Bid, Bak, and Bax and inhibited by Bcl-2 and Mcl-1.
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  • Michael White
  • Kurt Lackovic
  • Louise H Cengia
  • Lorraine A O'Reilly
  • Philippe Bouillet
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モンタニド ISA 50V をアジュバントした六価組換えタンパク質ワクチンの開発と急性トキソプラズマ症に対する保護効果の決定

Development of a hexavalent recombinant protein vaccine adjuvanted with Montanide ISA 50 V and determination of its protective efficacy against acute toxoplasmosis.
  • Esra Atalay Şahar
  • Hüseyin Can
  • Sultan Gülçe İz
  • Aysu Değirmenci Döşkaya
  • Mina Kalantari-Dehaghi
  • Remziye Deveci
  • Adnan Yüksel Gürüz
  • Mert Döşkaya
  • BMC Infect. Dis..2020 Jul;20(1):493. 10.1186/s12879-020-05220-2. doi: 10.1186/s12879-020-05220-2.Epub 2020-07-10.

PINK1-Parkinを介したミトファジーの活性化は、Fuchs社の角膜ジストロフィーにおけるミトコンドリア品質管理タンパク質を劣化させる

Activation of PINK1-Parkin-Mediated Mitophagy Degrades Mitochondrial Quality Control Proteins in Fuchs Endothelial Corneal Dystrophy.
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  • Shivakumar Vasanth
  • Geetha Melangath
  • Neha Deshpande
  • Varun Kumar
  • Anne-Sophie Benischke
  • Yuming Chen
  • Marianne O Price
  • Francis W Price
  • Ula V Jurkunas
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アフリカ系アメリカ人男性における理想的な心血管系の健康と自己申告健康、糖尿病、および脂肪率との関連

The association of ideal cardiovascular health with self-reported health, diabetes, and adiposity in African American males.
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  • Rosevine A Azap
  • James B Odei
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  • Rana Elgazzar
  • DeVeonne White
  • John Gregory
  • Joshua J Joseph
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