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日本語AIでPubMedを検索

日本語AIでPubMedを検索

PubMedの提供する医学論文データベースを日本語で検索できます。AI(Deep Learning)を活用した機械翻訳エンジンにより、精度高く日本語へ翻訳された論文をご参照いただけます。

みんなが読んでいる論文

限局性腎腫瘤に対する腎部分切除術後の周術期成績および手術マージンに及ぼす切除術の影響。プロスペクティブな多施設共同研究

Impact of Resection Technique on Perioperative Outcomes and Surgical Margins after Partial Nephrectomy for Localized Renal Masses: A Prospective Multicenter Study.
  • Andrea Minervini
  • Riccardo Campi
  • Brian R Lane
  • Ottavio De Cobelli
  • Francesco Sanguedolce
  • Georgios Hatzichristodoulou
  • Alessandro Antonelli
  • Sabrina Noyes
  • Andrea Mari
  • Oscar Rodriguez-Faba
  • Frank X Keeley
  • Johan Langenhuijsen
  • Gennaro Musi
  • Tobias Klatte
  • Marco Roscigno
  • Bulent Akdogan
  • Maria Furlan
  • Nihat Karakoyunlu
  • Martin Marszalek
  • Umberto Capitanio
  • Alessandro Volpe
  • Sabine Brookman-May
  • Jürgen E Gschwend
  • Marc C Smaldone
  • Robert G Uzzo
  • Marco Carini
  • Alexander Kutikov
  • J. Urol..2020 03;203(3):496-504. doi: 10.1097/JU.0000000000000591.Epub 2019-10-14.

TRPV1チャネルの活性化は、ポッドサイトにおける小胞体とミトコンドリアの接触を阻害することにより、糖尿病性腎症に拮抗する

Activation of TRPV1 channel antagonizes diabetic nephropathy through inhibiting endoplasmic reticulum-mitochondria contact in podocytes.
  • Xiao Wei
  • Xing Wei
  • Zongshi Lu
  • Li Li
  • Yingru Hu
  • Fang Sun
  • Yanli Jiang
  • Huan Ma
  • Hongting Zheng
  • Gangyi Yang
  • Daoyan Liu
  • Peng Gao
  • Zhiming Zhu
  • Metab. Clin. Exp..2020 04;105:154182. S0026-0495(20)30046-9. doi: 10.1016/j.metabol.2020.154182.Epub 2020-02-13.

非侵襲的な線維化マーカーであるFibrosis-4指数は、大腸がん肝転移に対する肝切除術後の生存率を予測する

Fibrosis-4 Index, a Noninvasive Fibrosis Marker, Predicts Survival Outcomes After Hepatectomy for Colorectal Cancer Liver Metastases.
  • Takahiko Akiyama
  • Yuji Miyamoto
  • Katsunori Imai
  • Yoichi Yamashita
  • Daichi Nomoto
  • Nobuya Daitoku
  • Yuki Sakamoto
  • Yuki Kiyozumi
  • Ryuma Tokunaga
  • Kojiro Eto
  • Kazuto Harada
  • Yukiharu Hiyoshi
  • Masaaki Iwatsuki
  • Yohei Nagai
  • Shiro Iwagami
  • Yoshifumi Baba
  • Naoya Yoshida
  • Hideo Baba
  • Ann. Surg. Oncol..2020 Jul;10.1245/s10434-020-08828-5. doi: 10.1245/s10434-020-08828-5.Epub 2020-07-09.

チロシンキナーゼ阻害薬は、転移性胃腸間質腫瘍患者の生存成績を有意に改善した:多施設コホート研究

Tyrosine kinase inhibitors significantly improved survival outcomes in patients with metastatic gastrointestinal stromal tumour: a multi-institutional cohort study.
  • A Deruchie Tan
  • K Willemsma
  • A MacNeill
  • K DeVries
  • A Srikanthan
  • C McGahan
  • T Hamilton
  • H Li
  • C D Blanke
  • C E Simmons
  • Curr Oncol.2020 Jun;27(3):e276-e282. conc-27-e276. doi: 10.3747/co.27.5869.Epub 2020-06-01.

間葉系上皮性卵巣癌細胞におけるLY75の抑制は、同所性異種移植マウスモデルにおいて、腫瘍の発生、広がりおよび治療抵抗性の向上と関連した安定なハイブリッドEOC細胞表現型を生成する

LY75 Suppression in Mesenchymal Epithelial Ovarian Cancer Cells Generates a Stable Hybrid EOC Cellular Phenotype, Associated with Enhanced Tumor Initiation, Spreading and Resistance to Treatment in Orthotopic Xenograft Mouse Model.
  • Sadia Mehdi
  • Elizabeth Macdonald
  • Kristianne Galpin
  • David A Landry
  • Galaxia Rodriguez
  • Barbara Vanderhyden
  • Dimcho Bachvarov
  • Int J Mol Sci.2020 Jul;21(14). E4992. doi: 10.3390/ijms21144992.Epub 2020-07-15.

Dientamoeba fragilis治療においてパロマイシンはメトロニダゾールよりも優れている

Paromomycin is superior to metronidazole in Dientamoeba fragilis treatment.
  • Ander Burgaña
  • Rosa Abellana
  • Stanislav Zlatanov Yordanov
  • Rabee Kazan
  • A Mauricio Pérez Ortiz
  • Cristina Castillo Ramos
  • Christian Garavito Hernández
  • Miriam Molina Rivero
  • Alessandra Queiroga Gonçalves
  • Emma Padilla
  • Josefa Pérez
  • Roger García-Puig
  • Tomas M Perez-Porcuna
  • Int J Parasitol Drugs Drug Resist.2019 12;11:95-100. S2211-3207(19)30140-X. doi: 10.1016/j.ijpddr.2019.10.005.Epub 2019-11-11.

アザチオプリン、塩酸クロニジン、クロピドグレル二硫酸塩、塩酸エタンブトール、グリセオフルビン、塩酸ヒドラジン、ニトロフラントインおよびチオグアニン経口懸濁液の安定性

Stability of Azathioprine, Clonidine Hydrochloride, Clopidogrel Bisulfate, Ethambutol Hydrochloride, Griseofulvin, Hydralazine Hydrochloride, Nitrofurantoin, and Thioguanine Oral Suspensions Compounded with SyrSpend SF pH4.
  • Hudson Polonini
  • Sharlene Loures da Silva
  • Carolina Neves Cunha
  • Anderson de Oliveira Ferreira
  • Korina Anagnostou
  • Eli Dijkers
  • Int J Pharm Compd.2020 May-Jun;24(3):252-262.

乳酸脱水素酵素と軽度のCOVID-19患者の悪化感受性:多施設非ステッド症例対照研究

Lactate dehydrogenase and susceptibility to deterioration of mild COVID-19 patients: a multicenter nested case-control study.
  • Jichan Shi
  • Yang Li
  • Xian Zhou
  • Qiran Zhang
  • Xinchun Ye
  • Zhengxing Wu
  • Xiangao Jiang
  • Hongying Yu
  • Lingyun Shao
  • Jing-Wen Ai
  • Haocheng Zhang
  • Bin Xu
  • Feng Sun
  • Wenhong Zhang
  • BMC Med.2020 06;18(1):168. 10.1186/s12916-020-01633-7. doi: 10.1186/s12916-020-01633-7.Epub 2020-06-03.

生理活性キナクリンと銀のハイブリッドナノ粒子による口腔癌幹細胞の細胞毒性と血管新生阻害の強化」の訂正。癌細胞の細胞毒性の増強:塩基切開修復カスケードの示唆」の訂正

Correction to "Enhancement of Cytotoxicity and Inhibition of Angiogenesis in Oral Cancer Stem Cells by a Hybrid Nanoparticle of Bioactive Quinacrine and Silver: Implication of Base Excision Repair Cascade".
  • Shakti Ranjan Satapathy
  • Sumit Siddharth
  • Dipon Das
  • Anmada Nayak
  • Chanakya Nath Kundu
  • Mol. Pharm..2020 Jul;doi: 10.1021/acs.molpharmaceut.0c00706.Epub 2020-07-17.

ホスホグルコムターゼ 1 欠損症(PGM1-CDG)の国際的コンセンサスガイドライン:診断、フォローアップおよび管理

International consensus guidelines for phosphoglucomutase 1 deficiency (PGM1-CDG): diagnosis, follow-up and management.
  • Ruqaiah Altassan
  • Silvia Radenkovic
  • Andrew C Edmondson
  • Rita Barone
  • Sandra Brasil
  • Anna Cechova
  • David Coman
  • Sarah Donoghue
  • Kristina Falkenstein
  • Vanessa Ferreira
  • Carlos Ferreira
  • Agata Fiumara
  • Rita Francsico
  • Hudson Freeze
  • Stephanie Grunewald
  • Tomas Honzik
  • Jaak Jaeken
  • Donna Krasnewich
  • Christina Lam
  • Joy Lee
  • Dirk Lefeber
  • Dorinda Marques-da-Silva
  • Carlota Pascoal
  • Dulce Quelhas
  • Kimiyo M Raymond
  • Daisy Rymen
  • Malgorzata Seroczynska
  • Mercedes Serrano
  • Jolanta Sykut-Cegielska
  • Christian Thiel
  • Frederic Tort
  • Mari-Anne Vals
  • Paula Videira
  • Nicol Voermans
  • Peter Witters
  • Eva Morava
  • J. Inherit. Metab. Dis..2020 Jul;doi: 10.1002/jimd.12286.Epub 2020-07-18.

経皮的経皮的経皮的血管形成術後の表在性大腿動脈裂孔の評価:カラーコードされたsummation画像と単色デジタルサブトラクション血管造影

Evaluation of superficial femoral artery-lesions after percutaneous transluminal angioplasty: color-coded summation images vs. monochromatic digital subtraction angiography.
  • Anne Marie Augustin
  • Irina Thein
  • Nicole Rickert
  • Thorsten Klink
  • Thorsten Alexander Bley
  • Ralph Kickuth
  • BMC Med Imaging.2020 Jun;20(1):67. 10.1186/s12880-020-00468-1. doi: 10.1186/s12880-020-00468-1.Epub 2020-06-18.

四面体DNAナノ構造体をベースとした多機能複合体の設計、作製、およびドラッグデリバリーおよび生物医学的治療への応用

Design, fabrication and applications of tetrahedral DNA nanostructure-based multifunctional complexes in drug delivery and biomedical treatment.
  • Tao Zhang
  • Taoran Tian
  • Ronghui Zhou
  • Songhang Li
  • Wenjuan Ma
  • Yuxin Zhang
  • Nanxin Liu
  • Sirong Shi
  • Qianshun Li
  • Xueping Xie
  • Yichen Ge
  • Mengting Liu
  • Qi Zhang
  • Shiyu Lin
  • Xiaoxiao Cai
  • Yunfeng Lin
  • Nat Protoc.2020 Jul;10.1038/s41596-020-0355-z. doi: 10.1038/s41596-020-0355-z.Epub 2020-07-15.

ジンバブエにおける多剤耐性およびリファンピシン耐性結核の治療成績:2010年から2015年の間に治療を開始した患者のコホート解析

Treatment outcomes of multi drug resistant and rifampicin resistant Tuberculosis in Zimbabwe: A cohort analysis of patients initiated on treatment during 2010 to 2015.
  • Ronnie Matambo
  • Kudakwashe C Takarinda
  • Pruthu Thekkur
  • Charles Sandy
  • Sungano Mharakurwa
  • Talent Makoni
  • Ronald Ncube
  • Kelvin Charambira
  • Christopher Zishiri
  • Mkhokheli Ngwenya
  • Saziso Nyathi
  • Albert Chiteka
  • Elliot Chikaka
  • Shungu Mutero-Munyati
  • PLoS ONE.2020;15(4):e0230848. PONE-D-19-16150. doi: 10.1371/journal.pone.0230848.Epub 2020-04-30.

多剤耐性結核患者における体格指数の変化のプロファイルの違い:レトロスペクティブコホート研究

Different profiles of body mass index variation among patients with multidrug-resistant tuberculosis: a retrospective cohort study.
  • Alhassane Diallo
  • Boubacar Djelo Diallo
  • Lansana Mady Camara
  • Lucrèce Ahouéfa Nadège Kounoudji
  • Boubacar Bah
  • Fulgence N'Zabintawali
  • Miguel Carlos-Bolumbu
  • Mamadou Hassimiou Diallo
  • Oumou Younoussa Sow
  • BMC Infect. Dis..2020 Apr;20(1):315. 10.1186/s12879-020-05028-0. doi: 10.1186/s12879-020-05028-0.Epub 2020-04-28.

RECIST 1.1、irRC、iRECIST基準に基づく半自動ソフトウェアによる免疫療法の奏効評価:主観的評価との比較

Response evaluation for immunotherapy through semi-automatic software based on RECIST 1.1, irRC, and iRECIST criteria: comparison with subjective assessment.
  • Ying-Chieh Lai
  • Wen-Cheng Chang
  • Chun-Bing Chen
  • Chi-Liang Wang
  • Yu-Fen Lin
  • Ming-Mo Ho
  • Chi-Yuan Cheng
  • Pei-Wei Huang
  • Chao-Wei Hsu
  • Gigin Lin
  • Acta Radiol.2020 Jul;61(7):983-991. doi: 10.1177/0284185119887588.Epub 2019-11-18.

高齢の非小細胞肺がん患者におけるプラチナ製剤ベースの化学療法。現実の世界で何を期待すべきか

Platinum-Based Chemotherapy in Older Patients with Non-Small Cell Lung Cancer: What to Expect in the Real World.
  • Giacomo Pelizzari
  • Francesco Cortiula
  • Marco Giavarra
  • Michele Bartoletti
  • Camilla Lisanti
  • Vanessa Buoro
  • Monica Cattaneo
  • Ciro Rossetto
  • Simona Rizzato
  • Fabio Puglisi
  • Marianna Macerelli
  • Gianpiero Fasola
  • Alessandro Follador
  • Drugs Aging.2020 Jul;10.1007/s40266-020-00785-8. doi: 10.1007/s40266-020-00785-8.Epub 2020-07-17.

発達期Wntシグナル伝達経路エフェクターβ-カテニン/TCFは、脂質代謝を調節する性ホルモンエストラジオールの肝機能を媒介している

The developmental Wnt signaling pathway effector β-catenin/TCF mediates hepatic functions of the sex hormone estradiol in regulating lipid metabolism.
  • Lili Tian
  • Weijuan Shao
  • Wilfred Ip
  • Zhuolun Song
  • Yasaman Badakhshi
  • Tianru Jin
  • PLoS Biol..2019 10;17(10):e3000444. PBIOLOGY-D-19-01324. doi: 10.1371/journal.pbio.3000444.Epub 2019-10-07.

新興汚染物質除去のための代替バイオプロセスに関するレビュー

A review on alternative bioprocesses for removal of emerging contaminants.
  • Aline Viancelli
  • William Michelon
  • Paula Rogovski
  • Rafael Dorighello Cadamuro
  • Estêvão Brasiliense de Souza
  • Gislaine Fongaro
  • Aline Frumi Camargo
  • Fábio Sptiza Stefanski
  • Bruno Venturin
  • Thamarys Scapini
  • Charline Bonatto
  • Karina Paula Preczeski
  • Natalia Klanovicz
  • Débora de Oliveira
  • Helen Treichel
  • Bioprocess Biosyst Eng.2020 Jul;10.1007/s00449-020-02410-9. doi: 10.1007/s00449-020-02410-9.Epub 2020-07-17.

PTSD治療のためのMDMA支援心理療法の長期追跡調査結果:6つの第2相試験の縦断的プール解析

Long-term follow-up outcomes of MDMA-assisted psychotherapy for treatment of PTSD: a longitudinal pooled analysis of six phase 2 trials.
  • Lisa Jerome
  • Allison A Feduccia
  • Julie B Wang
  • Scott Hamilton
  • Berra Yazar-Klosinski
  • Amy Emerson
  • Michael C Mithoefer
  • Rick Doblin
  • Psychopharmacology (Berl.).2020 Aug;237(8):2485-2497. 10.1007/s00213-020-05548-2. doi: 10.1007/s00213-020-05548-2.Epub 2020-06-04.

ヨーロッパ産ガラスウナギ(Anguilla anguilla)の行動とエネルギー関連遺伝子の転写反応にメチル水銀の新たな知見を得た

New insights into methylmercury induced behavioral and energy-related gene transcriptional responses in European glass eel (Anguilla anguilla).
  • Hengtong Liu
  • Amaia Lamarins
  • Jacques Labonne
  • Mathilde Monperrus
  • Pascale Coste
  • Emmanuel Huchet
  • Jacques Rives
  • Iban Seiliez
  • Valérie Bolliet
  • Chemosphere.2020 Sep;255:127020. S0045-6535(20)31213-3. doi: 10.1016/j.chemosphere.2020.127020.Epub 2020-05-10.

新生児のセボフルラン曝露は、その後のセボフルラン曝露の副作用に対する脆弱性の窓を広げ、デシタビン感受性機序を介して海馬の形態を変化させる

Neonatal exposure to sevoflurane expands the window of vulnerability to adverse effects of subsequent exposure to sevoflurane and alters hippocampal morphology via decitabine-sensitive mechanisms.
  • Yunan Lin
  • Lei Lei
  • Ling-Sha Ju
  • Ning Xu
  • Timothy E Morey
  • Nikolaus Gravenstein
  • Jianjun Yang
  • Anatoly E Martynyuk
  • Neurosci. Lett..2020 Jul;735:135240. S0304-3940(20)30510-3. doi: 10.1016/j.neulet.2020.135240.Epub 2020-07-07.

早期ホルモン陽性乳癌の女性における手術選択とその後の患者報告満足度の転帰との関係における人種差

Racial differences in the relationship between surgical choice and subsequent patient-reported satisfaction outcomes among women with early-stage hormone-positive breast cancer.
  • Prudvi Arabandi
  • Alexander N Slade
  • Arnethea L Sutton
  • Kandace P McGuire
  • Vanessa Sheppard
  • Breast Cancer Res. Treat..2020 Jul;10.1007/s10549-020-05784-2. doi: 10.1007/s10549-020-05784-2.Epub 2020-07-16.

p32/C1QBPは、ミトコンドリアの機能不全やアポトーシスに関連するミトコンドリアの連結性を維持するために、OMA1依存性のタンパク質分解処理を制御しています

p32/C1QBP regulates OMA1-dependent proteolytic processing of OPA1 to maintain mitochondrial connectivity related to mitochondrial dysfunction and apoptosis.
  • Solhee Noh
  • Sophors Phorl
  • Rema Naskar
  • Kakada Oeum
  • Yuri Seo
  • Eunjung Kim
  • Hee-Seok Kweon
  • Joo-Yong Lee
  • Sci Rep.2020 Jun;10(1):10618. 10.1038/s41598-020-67457-w. doi: 10.1038/s41598-020-67457-w.Epub 2020-06-30.

手術不能な慢性血栓塞栓性肺高血圧症に対するバルーン肺血管形成術:英国での経験

Balloon pulmonary angioplasty for inoperable chronic thromboembolic pulmonary hypertension: the UK experience.
  • Stephen P Hoole
  • John G Coghlan
  • John E Cannon
  • Dolores Taboada
  • Mark Toshner
  • Karen Sheares
  • Andrew John Fletcher
  • Guillermo Martinez
  • Alessandro Ruggiero
  • Nicholas Screaton
  • David Jenkins
  • Joanna Pepke-Zaba
  • Open Heart.2020;7(1):e001144. openhrt-2019-001144. doi: 10.1136/openhrt-2019-001144.Epub 2020-02-27.

胚性幹細胞由来心筋細胞における成熟心室サブタイプの優位性が生体内で増加している

Increased predominance of the matured ventricular subtype in embryonic stem cell-derived cardiomyocytes in vivo.
  • Hajime Ichimura
  • Shin Kadota
  • Toshihide Kashihara
  • Mitsuhiko Yamada
  • Kuniaki Ito
  • Hideki Kobayashi
  • Yuki Tanaka
  • Naoko Shiba
  • Shinichiro Chuma
  • Shugo Tohyama
  • Tatsuichiro Seto
  • Kenji Okada
  • Koichiro Kuwahara
  • Yuji Shiba
  • Sci Rep.2020 Jul;10(1):11883. 10.1038/s41598-020-68373-9. doi: 10.1038/s41598-020-68373-9.Epub 2020-07-17.

資源が限られた環境下で、初期の臨床的特徴と検査的特徴を用いて、重症化リスクの高いデング熱患者を同定すること

Identification of dengue patients with high risk of severe disease, using early clinical and laboratory features, in a resource-limited setting.
  • Madunil A Niriella
  • Isurujith K Liyanage
  • Arundathi Udeshika
  • Kasun V Liyanapathirana
  • Arjuna P De Silva
  • Hithnadura J de Silva
  • Arch. Virol..2020 Jul;10.1007/s00705-020-04720-5. doi: 10.1007/s00705-020-04720-5.Epub 2020-07-02.

ジカの時代における希望と信頼:ブラジルにおける流行の最前線にいる介護者と医療従事者の見解

Hope and trust in times of Zika: the views of caregivers and healthcare workers at the forefront of the epidemic in Brazil.
  • Clarissa Simas
  • Loveday Penn-Kekana
  • Hannah Kuper
  • Tereza Maciel Lyra
  • Maria Elisabeth Lopes Moreira
  • Maria do Socorro Veloso de Albuquerque
  • Thália Velho Barreto de Araújo
  • Ana Paula Lopes de Melo
  • Corina Helena Figueira Mendes
  • Martha Cristina Nunes Moreira
  • Marcos Antonio Ferreira do Nascimento
  • Camila Pimentel
  • Marcia Pinto
  • Sandra Valongueiro
  • Heidi Larson
  • Health Policy Plan.2020 Jul;czaa042. doi: 10.1093/heapol/czaa042.Epub 2020-07-18.