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日本語AIでPubMedを検索

日本語AIでPubMedを検索

PubMedの提供する医学論文データベースを日本語で検索できます。AI(Deep Learning)を活用した機械翻訳エンジンにより、精度高く日本語へ翻訳された論文をご参照いただけます。

みんなが読んでいる論文

日本人成人における食事性Na-K比と心血管疾患リスク因子:国民健康・栄養調査(2003年~2017年)のプールデータを用いたレトロスペクティブ横断的研究

Dietary sodium-to-potassium ratio and cardiovascular disease risk factors among Japanese adults: a retrospective cross-sectional study of pooled data from the National Health and Nutrition Survey, 2003-2017.
  • Emiko Okada
  • Chika Okada
  • Mai Matsumoto
  • Aya Fujiwara
  • Hidemi Takimoto
  • Br. J. Nutr..2020 Jul;:1-30. S000711452000269X. doi: 10.1017/S000711452000269X.Epub 2020-07-17.

Cyp1b1は、周産期肝臓におけるSrebp媒介のコレステロールおよびレチノイド合成を指示する;胎児発生時のレチノイン酸活性との関連

Cyp1b1 directs Srebp-mediated cholesterol and retinoid synthesis in perinatal liver; Association with retinoic acid activity during fetal development.
  • Meghan Maguire
  • Michele Campaigne Larsen
  • Chad M Vezina
  • Loredana Quadro
  • Youn-Kyung Kim
  • Sherry A Tanumihardjo
  • Colin R Jefcoate
  • PLoS ONE.2020;15(2):e0228436. PONE-D-18-08045. doi: 10.1371/journal.pone.0228436.Epub 2020-02-06.

ドイツで分離されたSpartina mottle virusの完全なゲノム配列から,Potyviridae(ポチウイルス科)の属名「Sparmovirus」に分類されることが明らかになった.

Complete genome sequence of a German isolate of spartina mottle virus supports its classification as a member of the proposed genus "Sparmovirus" within the family Potyviridae.
  • H Rose
  • W Menzel
  • D Knierim
  • F Rabenstein
  • Edgar Maiss
  • Arch. Virol..2020 Jul;10.1007/s00705-020-04726-z. doi: 10.1007/s00705-020-04726-z.Epub 2020-07-09.

メトホルミンのハロゲン化スルホンアミド誘導体の効果的な細胞輸送は、MCF-7細胞における抗増殖活性の向上とアポトーシス誘導に関連している

Effective Cellular Transport of -Halogenated Sulfonamide Derivatives of Metformin Is Related to Improved Antiproliferative Activity and Apoptosis Induction in MCF-7 Cells.
  • Magdalena Markowicz-Piasecka
  • Ibrahim Komeil
  • Johanna Huttunen
  • Joanna Sikora
  • Kristiina M Huttunen
  • Int J Mol Sci.2020 Mar;21(7). E2389. doi: 10.3390/ijms21072389.Epub 2020-03-30.

ミクソスポアレス感染に対するオリゴチャイテの免疫応答のトランスクリプトーム解析ミクソスポレウス属に感染したBranchiura sowerbyi

Transcriptomic analysis of oligochaete immune responses to myxosporeans infection: Branchiura sowerbyi infected with Myxobolus cultus.
  • Yuanli Zhao
  • Xinhua Liu
  • Bingwen Xi
  • Qianqian Zhang
  • Aihua Li
  • Jinyong Zhang
  • J. Invertebr. Pathol..2020 Jan;169:107283. S0022-2011(19)30184-3. doi: 10.1016/j.jip.2019.107283.Epub 2019-11-22.

SiPP(妊娠中および産後の脳卒中)。妊娠中および出産後の女性における脳血管疾患の病態生理学的メカニズム、臨床プロファイル、管理、転帰に関する前向き、観察的、国際的、多施設共同研究

SiPP (Stroke in Pregnancy and Postpartum): A prospective, observational, international, multicentre study on pathophysiological mechanisms, clinical profile, management and outcome of cerebrovascular diseases in pregnant and postpartum women.
  • Svetlana Lorenzano
  • Christine Kremer
  • Aleksandra Pavlovic
  • Dejana R Jovanovic
  • Else Charlotte Sandset
  • Hanne Christensen
  • Cheryl Bushnell
  • Anita Arsovska
  • Nikola Sprigg
  • Christine Roffe
  • Petra Ijäs
  • Zuzana Gdovinova
  • Anne Alexandrov
  • Marialuisa Zedde
  • Rossana Tassi
  • Monica Acciaresi
  • Maria Lantz
  • Katharina Sunnerhagen
  • Marija Zarkov
  • Kirsi Rantanen
  • Fabienne Perren
  • Helle K Iversen
  • Christina Kruuse
  • Agnieszka Slowik
  • Paola Palazzo
  • Janika Korv
  • Annette Fromm
  • Arijana Lovrencic-Huzjan
  • Eleni Korompoki
  • Ana Catarina Fonseca
  • Seana L Gall
  • Freimuth Brunner
  • Valeria Caso
  • Simona Sacco
  • Eur Stroke J.2020 Jun;5(2):193-203. 10.1177_2396987319893512. doi: 10.1177/2396987319893512.Epub 2019-12-06.

思春期の若者の睡眠に異なるトリプトファン/ラージニュートラルアミノ酸比を持つタンパク質の効果に関する無作為化二重盲検対照試験。PROTMORPHEUS研究

Randomized Double-Blind Controlled Trial on the Effect of Proteins with Different Tryptophan/Large Neutral Amino Acid Ratios on Sleep in Adolescents: The PROTMORPHEUS Study.
  • Oussama Saidi
  • Emmanuelle Rochette
  • Éric Doré
  • Freddy Maso
  • Julien Raoux
  • Fabien Andrieux
  • Maria Livia Fantini
  • Etienne Merlin
  • Bruno Pereira
  • Stéphane Walrand
  • Pascale Duché
  • Nutrients.2020 Jun;12(6). E1885. doi: 10.3390/nu12061885.Epub 2020-06-24.

手術後の上部消化管瘻の保存的治療における経腸栄養と非経口栄養の比較:多施設共同、無作為化、並行群、非盲検、第III相試験(NUTRILEAK試験)

Enteral versus parenteral nutrition in the conservative treatment of upper gastrointestinal fistula after surgery: a multicenter, randomized, parallel-group, open-label, phase III study (NUTRILEAK study).
  • Caroline Gronnier
  • Cécile Chambrier
  • Alain Duhamel
  • Benoît Dervaux
  • Denis Collet
  • Delphine Vaudoyer
  • Jean-Marc Régimbeau
  • Jacques Jougon
  • Jérémie Théréaux
  • Gil Lebreton
  • Julie Veziant
  • Alain Valverde
  • Pablo Ortega-Deballon
  • François Pattou
  • Muriel Mathonnet
  • Julie Perinel
  • Laura Beyer-Berjot
  • David Fuks
  • Philippe Rouanet
  • Jérémie H Lefevre
  • Pierre Cattan
  • Sophie Deguelte
  • Bernard Meunier
  • Jean-Jacques Tuech
  • Patrick Pessaux
  • Nicolas Carrere
  • Ephrem Salame
  • Eleonor Benaim
  • Bertrand Dousset
  • Simon Msika
  • Christophe Mariette
  • Guillaume Piessen
  • Trials.2020 Jun;21(1):448. 10.1186/s13063-020-04366-3. doi: 10.1186/s13063-020-04366-3.Epub 2020-06-02.

適応デザイン CONSORT Extension (ACE) ステートメント:適応デザインを用いた無作為化試験を報告するための説明と精緻化のためのガイドラインが記載されたチェックリスト

The Adaptive designs CONSORT Extension (ACE) statement: a checklist with explanation and elaboration guideline for reporting randomised trials that use an adaptive design.
  • Munyaradzi Dimairo
  • Philip Pallmann
  • James Wason
  • Susan Todd
  • Thomas Jaki
  • Steven A Julious
  • Adrian P Mander
  • Christopher J Weir
  • Franz Koenig
  • Marc K Walton
  • Jon P Nicholl
  • Elizabeth Coates
  • Katie Biggs
  • Toshimitsu Hamasaki
  • Michael A Proschan
  • John A Scott
  • Yuki Ando
  • Daniel Hind
  • Douglas G Altman
  • BMJ.2020 06;369:m115. doi: 10.1136/bmj.m115.Epub 2020-06-17.

質量分析に結合された生体適合性のある固相マイクロ抽出デバイスによる血漿サンプル中のエンドカンナビノイドの分析

Analysis of endocannabinoids in plasma samples by biocompatible solid-phase microextraction devices coupled to mass spectrometry.
  • Vinicius R Acquaro Junior
  • Germán Augusto Goméz-Ríos
  • Marcos Tascon
  • Maria Eugênia Costa Queiroz
  • Janusz Pawliszyn
  • Anal. Chim. Acta.2019 Dec;1091:135-145. S0003-2670(19)31045-1. doi: 10.1016/j.aca.2019.09.002.Epub 2019-09-05.

女性の先天性健康の改善:中央ペンシルバニア州女性健康調査におけるストロングヘルシーウーマン行動変容介入の長期的効果

Improving women's preconceptional health: long-term effects of the Strong Healthy Women behavior change intervention in the central Pennsylvania Women's Health Study.
  • Carol S Weisman
  • Marianne M Hillemeier
  • Danielle Symons Downs
  • Mark E Feinberg
  • Cynthia H Chuang
  • John J Botti
  • Anne-Marie Dyer
  • Womens Health Issues.2011 Jul-Aug;21(4):265-71. S1049-3867(11)00051-X. doi: 10.1016/j.whi.2011.03.007.Epub 2011-05-04.

パネス細胞アブレーションは、通常および高脂肪食後の急性壊死性膵炎のラットモデルにおける膵臓および腸の傷害を悪化させる

Paneth Cell Ablation Aggravates Pancreatic and Intestinal Injuries in a Rat Model of Acute Necrotizing Pancreatitis after Normal and High-Fat Diet.
  • Yuecheng Guo
  • Chunlan Huang
  • Liyan Liu
  • Xinyuan Fu
  • Yingying Lu
  • Junyuan Zheng
  • Qixiang Mei
  • Zehua Huang
  • Junjie Fan
  • Lungen Lu
  • Yue Zeng
  • Mediators Inflamm..2019;2019:8474523. doi: 10.1155/2019/8474523.Epub 2019-11-11.

暗闇下でのイネ中胚葉伸長を制御するためのカルリキンシグナル伝達の作用を明らかにした

Karrikin Signaling Acts Parallel to and Additively with Strigolactone Signaling to Regulate Rice Mesocotyl Elongation in Darkness.
  • Jianshu Zheng
  • Kai Hong
  • Longjun Zeng
  • Lei Wang
  • Shujing Kang
  • Minghao Qu
  • Jiarong Dai
  • Linyuan Zou
  • Lixin Zhu
  • Zhanpeng Tang
  • Xiangbing Meng
  • Bing Wang
  • Jiang Hu
  • Yonghui Zhao
  • Dali Zeng
  • Peng Cui
  • Quan Wang
  • Qian Qian
  • Yonghong Wang
  • Jiayang Li
  • Guosheng Xiong
  • Plant Cell.2020 Jul;tpc.00123.2020. doi: 10.1105/tpc.20.00123.Epub 2020-07-14.

非都市部の薬物注入者における日常的な薬物使用と危害軽減サービス利用の生態学的瞬間評価。同時並行混合方法による実現可能性調査

Ecological momentary assessment of daily drug use and harm reduction service utilization among people who inject drugs in non-urban areas: A concurrent mixed-method feasibility study.
  • Katie Biello
  • Peter Salhaney
  • Pablo K Valente
  • Ellen Childs
  • Jennifer Olson
  • Joel J Earlywine
  • Brandon Dl Marshall
  • Angela R Bazzi
  • Drug Alcohol Depend.2020 Jul;214:108167. S0376-8716(20)30332-X. doi: 10.1016/j.drugalcdep.2020.108167.Epub 2020-07-10.

ナノインク変性フレキシブルペーパー基板を用いた前立腺特異抗原へのビオチン化抗体の結合を利用したPSAモニタリングのための新規免疫センサー:バイオセンシング技術を用いた効率的な癌診断法の開発

A novel immunosensor for the monitoring of PSA using binding of biotinylated antibody to the prostate specific antigen based on nano-ink modified flexible paper substrate: efficient method for diagnosis of cancer using biosensing technology.
  • Fatemeh Farschi
  • Arezoo Saadati
  • Mohammad Hasanzadeh
  • Heliyon.2020 Jul;6(7):e04327. S2405-8440(20)31171-3. doi: 10.1016/j.heliyon.2020.e04327.Epub 2020-07-07.

体外受精のための卵巣刺激を受けたピーク血清プロゲステロン値上昇患者に対するGnRHアゴニストの中止とGnRHアンタゴニストの多剤併用:概念実証試験

Stop GnRH-Agonist Combined with Multiple-Dose GnRH-Antagonist for Patients with Elevated Peak Serum Progesterone Levels Undergoing Ovarian Stimulation for IVF: A Proof of Concept.
  • Raoul Orvieto
  • Michal Kirshenbaum
  • Valentina Galiano
  • Eran Zilberberg
  • Jigal Haas
  • Ravit Nahum
  • Gynecol. Obstet. Invest..2020 Jun;:1-5. 000508875. doi: 10.1159/000508875.Epub 2020-06-24.

ヒト B 細胞のクローン拡大と SARS-CoV-2 に対する抗体応答の収束

Human B cell clonal expansion and convergent antibody responses to SARS-CoV-2.
  • Sandra C A Nielsen
  • Fan Yang
  • Katherine J L Jackson
  • Ramona A Hoh
  • Katharina Röltgen
  • Bryan Stevens
  • Ji-Yeun Lee
  • Arjun Rustagi
  • Angela J Rogers
  • Abigail E Powell
  • Javaria Najeeb
  • Ana R Otrelo-Cardoso
  • Kathryn E Yost
  • Bence Daniel
  • Howard Y Chang
  • Ansuman T Satpathy
  • Theodore S Jardetzky
  • Peter S Kim
  • Taia T Wang
  • Benjamin A Pinsky
  • Catherine A Blish
  • Scott D Boyd
  • bioRxiv.2020 Jul;2020.07.08.194456. doi: 10.1101/2020.07.08.194456.Epub 2020-07-09.

応答面法を用いた超臨界流体システムによるレモンバーベナ葉からのフェニルプロパノイドとフラボノイドの最適化抽出

Optimized Extraction of Phenylpropanoids and Flavonoids from Lemon Verbena Leaves by Supercritical Fluid System Using Response Surface Methodology.
  • Francisco Javier Leyva-Jiménez
  • Jesús Lozano-Sánchez
  • Álvaro Fernández-Ochoa
  • María de la Luz Cádiz-Gurrea
  • David Arráez-Román
  • Antonio Segura-Carretero
  • Foods.2020 Jul;9(7). E931. doi: 10.3390/foods9070931.Epub 2020-07-14.

様々な商品におけるオキサチアピプロリンの既存の最大残留レベルの変更と輸入許容値の設定

Modification of the existing maximum residue levels and setting of import tolerances for oxathiapiprolin in various commodities.
  • Maria Anastassiadou
  • Alba Brancato
  • Luis Carrasco Cabrera
  • Luna Greco
  • Samira Jarrah
  • Aija Kazocina
  • Renata Leuschner
  • Jose Oriol Magrans
  • Ileana Miron
  • Stefanie Nave
  • Ragnor Pedersen
  • Marianna Raczyk
  • Hermine Reich
  • Silvia Ruocco
  • Angela Sacchi
  • Miguel Santos
  • Alois Stanek
  • Anne Theobald
  • Benedicte Vagenende
  • Alessia Verani
  • EFSA J.2019 Jul;17(7):e05759. EFS25759. doi: 10.2903/j.efsa.2019.5759.Epub 2019-07-25.

ビタミンA欠乏は、バルプロ酸誘発ラット自閉症モデルにおいて、自閉症様行動と腸神経系の異常を悪化させる

Vitamin A deficiency exacerbates autism-like behaviors and abnormalities of the enteric nervous system in a valproic acid-induced rat model of autism.
  • Boli Cheng
  • Jiang Zhu
  • Ting Yang
  • Si Wang
  • Huan Liu
  • Qionghui Wu
  • Xinhui Zhang
  • Jie Chen
  • Tingyu Li
  • Neurotoxicology.2020 Jul;79:184-190. S0161-813X(20)30091-7. doi: 10.1016/j.neuro.2020.06.004.Epub 2020-06-08.

巨大種子の起源について:ダブルココナッツ(Lodoicea maldivica)とその近縁種(Borasseae, Arecaceae)のマクロ進化

On the origin of giant seeds: the macroevolution of the double coconut (Lodoicea maldivica) and its relatives (Borasseae, Arecaceae).
  • Sidonie Bellot
  • Ross P Bayton
  • Thomas L P Couvreur
  • Steven Dodsworth
  • Wolf L Eiserhardt
  • Maïté S Guignard
  • Hugh W Pritchard
  • Lucy Roberts
  • Peter E Toorop
  • William J Baker
  • New Phytol..2020 Jun;doi: 10.1111/nph.16750.Epub 2020-06-16.

ヒストンメチル化酵素KMT2Dをコードする遺伝子の機能喪失は、ミトコンドリア呼吸の調節障害につながる

Loss of Function of the Gene Encoding the Histone Methyltransferase KMT2D Leads to Deregulation of Mitochondrial Respiration.
  • Consiglia Pacelli
  • Iolanda Adipietro
  • Natascia Malerba
  • Gabriella Maria Squeo
  • Claudia Piccoli
  • Angela Amoresano
  • Gabriella Pinto
  • Pietro Pucci
  • Ji-Eun Lee
  • Kai Ge
  • Nazzareno Capitanio
  • Giuseppe Merla
  • Cells.2020 Jul;9(7). E1685. doi: 10.3390/cells9071685.Epub 2020-07-13.

調節性T細胞は、特発性早産/出産のサブセットと有害な新生児のアウトカムで役割を果たしています

Regulatory T Cells Play a Role in a Subset of Idiopathic Preterm Labor/Birth and Adverse Neonatal Outcomes.
  • Nardhy Gomez-Lopez
  • Marcia Arenas-Hernandez
  • Roberto Romero
  • Derek Miller
  • Valeria Garcia-Flores
  • Yaozhu Leng
  • Yi Xu
  • Jose Galaz
  • Sonia S Hassan
  • Chaur-Dong Hsu
  • Harley Tse
  • Carmen Sanchez-Torres
  • Bogdan Done
  • Adi L Tarca
  • Cell Rep.2020 Jul;32(1):107874. S2211-1247(20)30855-X. doi: 10.1016/j.celrep.2020.107874.

チリ北部の海水淡水化プラントからの逆浸透膜(ROM)からのバイオファウリングの特性評価と除去を、sp. Ni1-LEM上清を用いて行った

Characterization and removal of biofouling from reverse osmosis membranes (ROMs) from a desalination plant in Northern Chile, using sp. Ni1-LEM supernatant.
  • Hernán Vera-Villalobos
  • Vilma Pérez
  • Francisco Contreras
  • Valezka Alcayaga
  • Vladimir Avalos
  • Carlos Riquelme
  • Fernando Silva-Aciares
  • Biofouling.2020 Jun;:1-11. doi: 10.1080/08927014.2020.1776268.Epub 2020-06-16.

中性子回折、FマジックアングルスピニングNMR、密度汎関数理論計算を組み合わせたThFの結晶構造の解明

Insight into the Crystalline Structure of ThF with the Combined Use of Neutron Diffraction, F Magic-Angle Spinning-NMR, and Density Functional Theory Calculations.
  • Laura Martel
  • Elisa Capelli
  • Monique Body
  • Marco Klipfel
  • Ondrej Beneš
  • Louis Maksoud
  • Phillipe E Raison
  • Emmanuelle Suard
  • Lucas Visscher
  • Catherine Bessada
  • Christophe Legein
  • Thibault Charpentier
  • Attila Kovács
  • Inorg Chem.2018 Dec;57(24):15350-15360. doi: 10.1021/acs.inorgchem.8b02683.Epub 2018-11-26.

ハイリスク妊婦の早産予防のための膣と筋肉内プロゲストーゲンの比較(VICTORIA試験):多施設共同、オープンラベル無作為化試験およびメタアナリシス

Vaginal compared with intramuscular progestogen for preventing preterm birth in high-risk pregnant women (VICTORIA study): a multicentre, open-label randomised trial and meta-analysis.
  • S-J Choi
  • D W Kwak
  • K Kil
  • S-C Kim
  • J-Y Kwon
  • Y H Kim
  • S Na
  • J-G Bae
  • H-H Cha
  • J-Y Shim
  • K Y Oh
  • K A Lee
  • S M Kim
  • I A Cho
  • S M Lee
  • G J Cho
  • Y S Jo
  • G Y Choi
  • S K Choi
  • S E Hur
  • H S Hwang
  • Y J Kim
  • BJOG.2020 Jun;doi: 10.1111/1471-0528.16365.Epub 2020-06-14.

ジストログリカンの喪失は、欠損したミトーシス媒介のゲノム不安定性を介して細胞の老化を促進する

Loss of Dystroglycan Drives Cellular Senescence via Defective Mitosis-Mediated Genomic Instability.
  • Guadalupe Elizabeth Jimenez-Gutierrez
  • Ricardo Mondragon-Gonzalez
  • Luz Adriana Soto-Ponce
  • Wendy Lilián Gómez-Monsiváis
  • Ian García-Aguirre
  • Ruth Abigail Pacheco-Rivera
  • Rocío Suárez-Sánchez
  • Andrea Brancaccio
  • Jonathan Javier Magaña
  • Rita C R Perlingeiro
  • Bulmaro Cisneros
  • Int J Mol Sci.2020 Jul;21(14). E4961. doi: 10.3390/ijms21144961.Epub 2020-07-14.

β-カテニンは、eNOS活性と流れに依存した抗アポトーシス遺伝子の発現を制御することで、内皮細胞の生存を促進する

β-catenin promotes endothelial survival by regulating eNOS activity and flow-dependent anti-apoptotic gene expression.
  • Virginia Tajadura
  • Marie Haugsten Hansen
  • Joy Smith
  • Hannah Charles
  • Matthew Rickman
  • Keith Farrell-Dillon
  • Vasco Claro
  • Christina Warboys
  • Albert Ferro
  • Cell Death Dis.2020 Jun;11(6):493. 10.1038/s41419-020-2687-6. doi: 10.1038/s41419-020-2687-6.Epub 2020-06-30.

HSP90インヒビターが循環停止後のドネーションのポルシンモデルにおける肺保護を改善する

HSP90 Inhibitor Improves Lung Protection in Porcine Model of Donation after Circulatory Arrest.
  • Basil S Nasir
  • Caroline Landry
  • Ahmed Menaouar
  • Jean-François Germain
  • Shant Der Sarkissian
  • Louis-Mathieu Stevens
  • Henry Aceros
  • Jean-François Cailhier
  • Charles Leduc
  • Moishe Liberman
  • Nicolas Noiseux
  • Pasquale Ferraro
  • Ann. Thorac. Surg..2020 Jul;S0003-4975(20)31111-5. doi: 10.1016/j.athoracsur.2020.05.079.Epub 2020-07-08.

ビタミンB12の状態のバイオマーカーに対するホエイプロテインサプリメントとレジスタンストレーニングの効果。健康な高齢者における 1 年間の無作為化介入(CALM 試験)

Effects of Prolonged Whey Protein Supplementation and Resistance Training on Biomarkers of Vitamin B12 Status: A 1-Year Randomized Intervention in Healthy Older Adults (the CALM Study).
  • Eva Greibe
  • Søren Reitelseder
  • Rasmus L Bechshøft
  • Jacob Bülow
  • Grith W Højfeldt
  • Simon R Schacht
  • Mads L Knudsen
  • Inge Tetens
  • Marie S Ostenfeld
  • Ulla R Mikkelsen
  • Christian W Heegaard
  • Ebba Nexo
  • Lars Holm
  • Nutrients.2020 Jul;12(7). E2015. doi: 10.3390/nu12072015.Epub 2020-07-07.

生物学的時代の潰瘍性大腸炎患者における大腸摘出術後の罹患率と死亡率の傾向(2002-2013年)。全国の入院患者サンプルを用いた研究

Trends in Morbidity and Mortality Following Colectomy Among Patients with Ulcerative Colitis in the Biologic Era (2002-2013): A Study Using the National Inpatient Sample.
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  • Benjamin D Renelus
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2004年から2014年までのCoRISコホートにおけるHIV感染者の男女間の疫学および死亡率の違い

Differences in epidemiology and mortality between men and women with HIV infection in the CoRIS cohort from 2004 to 2014.
  • Constanza Muñoz Hornero
  • Alfonso Muriel
  • Marta Montero
  • José Antonio Iribarren
  • Mar Masía
  • Leopoldo Muñoz
  • Gloria Sampériz
  • Gemma Navarro
  • Santiago Moreno
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  • Enferm. Infecc. Microbiol. Clin..2020 Jul;S0213-005X(20)30220-2. doi: 10.1016/j.eimc.2020.05.021.Epub 2020-07-14.

lncRNA ZEB1-AS1は、糖尿病性腎症におけるmiR-216a-5p/BMP7軸を制御することにより、高グルコース誘導性EMTと線維芽細胞増殖を抑制することを明らかにした

lncRNA ZEB1-AS1 inhibits high glucose-induced EMT and fibrogenesis by regulating the miR-216a-5p/BMP7 axis in diabetic nephropathy.
  • Qingqing Meng
  • Xiaolin Zhai
  • Yi Yuan
  • Qing Ji
  • Pengyuan Zhang
  • Braz. J. Med. Biol. Res..2020;53(4):e9288. S0100-879X2020000400607. doi: 10.1590/1414-431X20209288.Epub 2020-04-09.

健康なボランティアおよびHIV-1感染者におけるマラビロクの薬物動態および/または有効性にCYP3A5遺伝子多型が及ぼす臨床的影響はなかった

No Clinical Impact of CYP3A5 Gene Polymorphisms on the Pharmacokinetics and/or Efficacy of Maraviroc in Healthy Volunteers and HIV-1-Infected Subjects.
  • Manoli Vourvahis
  • Lynn McFadyen
  • Sunil Nepal
  • Srinivas Rao Valluri
  • Annie Fang
  • Gwendolyn D Fate
  • Linda S Wood
  • Jean-Claude Marshall
  • Phylinda L S Chan
  • Angus Nedderman
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  • Mark E Savage
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グルココルチコイド治療を受けている患者の骨密度に対するカルシウムおよびビタミンD化合物の効果:ネットワークメタアナリシス

The effect of calcium and vitamin D compounds on bone mineral density in patients undergoing glucocorticoid therapies: a network meta-analysis.
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  • Zachary Silver
  • Emma Huang
  • Elena Zheng
  • Kyra Kavanagh
  • Jannusha Panicker
  • Clin. Rheumatol..2020 Jul;10.1007/s10067-020-05294-y. doi: 10.1007/s10067-020-05294-y.Epub 2020-07-17.

COVID-19の肝機能への影響:北イタリアの内科ユニットからの結果

Impact of COVID-19 on liver function: results from an internal medicine unit in Northern Italy.
  • Marco Vincenzo Lenti
  • Federica Borrelli de Andreis
  • Ivan Pellegrino
  • Catherine Klersy
  • Stefania Merli
  • Emanuela Miceli
  • Nicola Aronico
  • Caterina Mengoli
  • Michele Di Stefano
  • Sara Cococcia
  • Giovanni Santacroce
  • Simone Soriano
  • Federica Melazzini
  • Mariangela Delliponti
  • Fausto Baldanti
  • Antonio Triarico
  • Gino Roberto Corazza
  • Massimo Pinzani
  • Antonio Di Sabatino
  • Intern Emerg Med.2020 Jul;10.1007/s11739-020-02425-w. doi: 10.1007/s11739-020-02425-w.Epub 2020-07-10.

限局性前立腺癌に対する高線量率ブラキセラピーは、腫瘍を冷たい状態から熱い状態に変える

High dose-rate brachytherapy of localized prostate cancer converts tumors from cold to hot.
  • Simon P Keam
  • Heloise Halse
  • Thu Nguyen
  • Minyu Wang
  • Nicolas Van Kooten Losio
  • Catherine Mitchell
  • Franco Caramia
  • David J Byrne
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  • Georgina Ryland
  • Phillip K Darcy
  • Shahneen Sandhu
  • Piers Blombery
  • Ygal Haupt
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  • J Immunother Cancer.2020 Jun;8(1). e000792. doi: 10.1136/jitc-2020-000792.

未治療のB型慢性肝炎患者における自然免疫応答および適応免疫応答のサイトカインプロファイルと臨床的・生物学的特徴との関連

Association among cytokine profiles of innate and adaptive immune responses and clinical-virological features in untreated patients with chronic hepatitis B.
  • Yurong Gu
  • Yifan Lian
  • Qiaolan Zheng
  • Zexuan Huang
  • Lin Gu
  • Yanhua Bi
  • Jing Li
  • Yanlin Huang
  • Yuankai Wu
  • Lubiao Chen
  • Yuehua Huang
  • BMC Infect. Dis..2020 Jul;20(1):509. 10.1186/s12879-020-05233-x. doi: 10.1186/s12879-020-05233-x.Epub 2020-07-14.

硫黄マスタードに暴露されたイランの退役軍人における酸化ストレスの増加と関連したテロメア短縮

Telomere shortening associated with increased levels of oxidative stress in sulfur mustard-exposed Iranian veterans.
  • Effat Behravan
  • Seyed Adel Moallem
  • Fatemeh Kalalinia
  • Mahnaz Ahmadimanesh
  • Peter Blain
  • Paul Jowsey
  • Shahriar Khateri
  • Mohammad Mahdi Forghanifard
  • Mahdi BalaliMood
  • Mutat Res Genet Toxicol Environ Mutagen.2018 Oct;834:1-5. S1383-5718(17)30355-8. doi: 10.1016/j.mrgentox.2018.06.017.Epub 2018-06-20.

GETECCUによるENEIDA登録(炎症性腸疾患の遺伝的・環境的決定要因に関する全国的研究):デザイン、モニタリング、機能

The ENEIDA registry (Nationwide study on genetic and environmental determinants of inflammatory bowel disease) by GETECCU: Design, monitoring and functions.
  • Yamile Zabana
  • Julián Panés
  • Pilar Nos
  • Fernando Gomollón
  • Maria Esteve
  • Valle García-Sánchez
  • Javier P Gisbert
  • Manuel Barreiro-de-Acosta
  • Eugeni Domènech
  • Gastroenterol Hepatol.2020 Jul;S0210-5705(20)30165-5. doi: 10.1016/j.gastrohep.2020.05.007.Epub 2020-07-13.

DNAメチル化に基づくテロメア長の推定法

DNA methylation-based estimator of telomere length.
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  • Pei-Chien Tsai
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  • Charles Kooperberg
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  • Eric A Whitsel
  • Themistocles L Assimes
  • Wei Chen
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Min Gong et al: (Risk for Infections During Treatment with Denosumab for Osteoporosis: a Systematic Review and Metaanalysis)からの編集者への手紙への回答

Response to Letter to the Editor from Min Gong et al: (Risk for Infections During Treatment with Denosumab for Osteoporosis: a Systematic Review and Meta-analysis).
  • Talia Diker-Cohen
  • Dana Rosenberg
  • Tomer Avni
  • Daniel Shepshelovich
  • Gloria Tsvetov
  • Anat Gafter-Gvili
  • J. Clin. Endocrinol. Metab..2020 Jul;dgaa446. doi: 10.1210/clinem/dgaa446.Epub 2020-07-17.

ヒト膵臓癌における細胞浸潤・遊走を制御する細胞外小胞輸送を介した長鎖ノンコーディングRNA HULCとMicroRNA-622の相互作用

The Interaction Between Long Non-coding RNA HULC and MicroRNA-622 via Transfer by Extracellular Vesicles Regulates Cell Invasion and Migration in Human Pancreatic Cancer.
  • Kenji Takahashi
  • Kazuya Koyama
  • Yu Ota
  • Hidetaka Iwamoto
  • Keisuke Yamakita
  • Satoshi Fujii
  • Yohei Kitano
  • Front Oncol.2020;10:1013. doi: 10.3389/fonc.2020.01013.Epub 2020-06-23.

腸骨大腿部深部静脈血栓症の治療におけるAngioJet Pharmacomechanical Thrombectomyおよびカテーテル指示型血栓溶解療法とカテーテル指示型血栓溶解療法のみの比較。単一施設のレトロスペクティブコホート研究

AngioJet Pharmacomechanical Thrombectomy and Catheter Directed Thrombolysis vs. Catheter Directed Thrombolysis Alone for the Treatment of Iliofemoral Deep Vein Thrombosis: A Single Centre Retrospective Cohort Study.
  • Anna L Pouncey
  • Adam M Gwozdz
  • Oscar W Johnson
  • Justinas Silickas
  • Prakash Saha
  • Narayan Thulasidasan
  • Narayan Karunanithy
  • Ander T Cohen
  • Stephen A Black
  • Eur J Vasc Endovasc Surg.2020 Jul;S1078-5884(20)30423-8. doi: 10.1016/j.ejvs.2020.05.006.Epub 2020-07-11.

1.5Tおよび3TでのMRI時の両側DBSインプラント近傍組織のRF誘導加熱:外科的リード管理の役割

RF-induced heating in tissue near bilateral DBS implants during MRI at 1.5 T and 3T: The role of surgical lead management.
  • Laleh Golestanirad
  • John Kirsch
  • Giorgio Bonmassar
  • Sean Downs
  • Behzad Elahi
  • Alastair Martin
  • Maria-Ida Iacono
  • Leonardo M Angelone
  • Boris Keil
  • Lawrence L Wald
  • Julie Pilitsis
  • Neuroimage.2019 01;184:566-576. S1053-8119(18)30819-X. doi: 10.1016/j.neuroimage.2018.09.034.Epub 2018-09-19.

黄斑変性症に対するHLAマッチ同種iPS細胞由来RPE移植

HLA-Matched Allogeneic iPS Cells-Derived RPE Transplantation for Macular Degeneration.
  • Sunao Sugita
  • Michiko Mandai
  • Yasuhiko Hirami
  • Seiji Takagi
  • Tadao Maeda
  • Masashi Fujihara
  • Mitsuhiro Matsuzaki
  • Midori Yamamoto
  • Kyoko Iseki
  • Naoko Hayashi
  • Ayumi Hono
  • Shoko Fujino
  • Naoshi Koide
  • Noriko Sakai
  • Yumiko Shibata
  • Motoki Terada
  • Mitsuhiro Nishida
  • Hiromi Dohi
  • Masaki Nomura
  • Naoki Amano
  • Hirokazu Sakaguchi
  • Chikako Hara
  • Kazuichi Maruyama
  • Takashi Daimon
  • Masataka Igeta
  • Toshihiko Oda
  • Utako Shirono
  • Misato Tozaki
  • Kota Totani
  • Satoshi Sugiyama
  • Kohji Nishida
  • Yasuo Kurimoto
  • Masayo Takahashi
  • J Clin Med.2020 Jul;9(7). E2217. doi: 10.3390/jcm9072217.Epub 2020-07-13.

中等度および重度の過活動膀胱に対する電気鍼治療とソリフェナシンの効果:多施設、無作為化比較試験プロトコール

Effect of electroacupuncture versus solifenacin for moderate and severe overactive bladder: a multi-centre, randomized controlled trial study protocol.
  • Qian Wen
  • Ning Li
  • Xueling Wang
  • Hao Li
  • Fengwei Tian
  • Weiwei Chen
  • Yanyan Lu
  • Zhishun Liu
  • BMC Complement Med Ther.2020 Jul;20(1):224. 10.1186/s12906-020-03018-y. doi: 10.1186/s12906-020-03018-y.Epub 2020-07-16.

神経細胞の塩化物押し出しを強化することで、神経障害性疼痛におけるα2/α3 GABAを介した鎮痛効果を回復させる

Enhancing neuronal chloride extrusion rescues α2/α3 GABA-mediated analgesia in neuropathic pain.
  • Louis-Etienne Lorenzo
  • Antoine G Godin
  • Francesco Ferrini
  • Karine Bachand
  • Isabel Plasencia-Fernandez
  • Simon Labrecque
  • Alexandre A Girard
  • Dominic Boudreau
  • Irenej Kianicka
  • Martin Gagnon
  • Nicolas Doyon
  • Alfredo Ribeiro-da-Silva
  • Yves De Koninck
  • Nat Commun.2020 02;11(1):869. 10.1038/s41467-019-14154-6. doi: 10.1038/s41467-019-14154-6.Epub 2020-02-13.

大動脈平滑筋における電圧依存性KチャネルとSERCAポンプの活性化を介したゲミグリプチンの血管拡張作用

The vasodilatory effect of gemigliptin via activation of voltage-dependent K channels and SERCA pumps in aortic smooth muscle.
  • Hee Seok Jung
  • Mi Seon Seo
  • Jin Ryeol An
  • Minji Kang
  • Ryeon Heo
  • Hongliang Li
  • Won-Kyo Jung
  • Il-Whan Choi
  • Eun-Hee Cho
  • Hongzoo Park
  • Young Min Bae
  • Won Sun Park
  • Eur. J. Pharmacol..2020 Jun;882:173243. S0014-2999(20)30335-6. doi: 10.1016/j.ejphar.2020.173243.Epub 2020-06-12.

雌ニホンウズラの肝臓に及ぼす鉛の慢性曝露の影響:病理組織学的損傷、酸化ストレス、AMP活性化プロテインキナーゼに基づく脂質代謝障害

The effects of chronic lead exposure on the liver of female Japanese quail (Coturnix japonica): Histopathological damages, oxidative stress and AMP-activated protein kinase based lipid metabolism disorder.
  • Honghong Kou
  • Jing Ya
  • Xuebin Gao
  • Hongfeng Zhao
  • Ecotoxicol. Environ. Saf..2020 Mar;190:110055. S0147-6513(19)31386-7. doi: 10.1016/j.ecoenv.2019.110055.Epub 2019-12-12.

KLHL24の不活性化に伴う致死性不整脈を伴う心筋症

Cardiomyopathy with lethal arrhythmias associated with inactivation of KLHL24.
  • Carola Hedberg-Oldfors
  • Alexandra Abramsson
  • Daniel P S Osborn
  • Olof Danielsson
  • Afsoon Fazlinezhad
  • Yalda Nilipour
  • Laila Hübbert
  • Inger Nennesmo
  • Kittichate Visuttijai
  • Jaipreet Bharj
  • Evmorfia Petropoulou
  • Azza Shoreim
  • Barbara Vona
  • Najmeh Ahangari
  • Marcela Dávila López
  • Mohammad Doosti
  • Rakesh Kumar Banote
  • Reza Maroofian
  • Malin Edling
  • Mehdi Taherpour
  • Henrik Zetterberg
  • Ehsan Ghayoor Karimiani
  • Anders Oldfors
  • Yalda Jamshidi
  • Hum. Mol. Genet..2019 06;28(11):1919-1929. 5305756. doi: 10.1093/hmg/ddz032.

中等度から重度の肺疾患を有する嚢胞性線維症患者の気道マイクロバイオームのアンターゲットメタゲノム調査

Untargeted Metagenomic Investigation of the Airway Microbiome of Cystic Fibrosis Patients with Moderate-Severe Lung Disease.
  • Giovanni Bacci
  • Giovanni Taccetti
  • Daniela Dolce
  • Federica Armanini
  • Nicola Segata
  • Francesca Di Cesare
  • Vincenzina Lucidi
  • Ersilia Fiscarelli
  • Patrizia Morelli
  • Rosaria Casciaro
  • Anna Negroni
  • Alessio Mengoni
  • Annamaria Bevivino
  • Microorganisms.2020 Jul;8(7). E1003. doi: 10.3390/microorganisms8071003.Epub 2020-07-04.

使い捨てピペット抽出法と超高速液体クロマトグラフィー・タンデム質量分析法による脳脊髄液試料中のアナンダミドの定量

Determination of anandamide in cerebrospinal fluid samples by disposable pipette extraction and ultra-high performance liquid chromatography tandem mass spectrometry.
  • Igor Gustavo de Carvalho Oliveira
  • Camila Marchioni
  • Maria Eugênia Costa Queiroz
  • J. Chromatogr. B Analyt. Technol. Biomed. Life Sci..2019 Nov;1130-1131:121809. S1570-0232(19)30687-7. doi: 10.1016/j.jchromb.2019.121809.Epub 2019-10-04.

ウィスターラットの実験的に誘発された微小結晶性関節炎における滑膜炎症過程のレーザー治療

Laser treatment of synovial inflammatory process in experimentally induced microcrystalline arthritis in Wistar rats.
  • Débora Mara Fortes Bartoli
  • Airton Luiz Felizatti
  • Fernando Russo Costa do Bomfim
  • Julia Leme Bovo
  • Andrea Aparecida de Aro
  • Maria Esméria Corezzola do Amaral
  • Marcelo Augusto Marretto Esquisatto
  • Lasers Med Sci.2020 Jun;10.1007/s10103-020-03055-6. doi: 10.1007/s10103-020-03055-6.Epub 2020-06-10.

術前の血糖値とヘモグロビンa1c値は、ペニス埋入術を受ける糖尿病男性における術後感染症の予測にはならない

Immediate preoperative blood glucose and hemoglobin a1c levels are not predictive of postoperative infections in diabetic men undergoing penile prosthesis placement.
  • Mohamad M Osman
  • Linda M Huynh
  • Farouk M El-Khatib
  • Maxwell Towe
  • Huang-Wei Su
  • Robert Andrianne
  • Gregory Barton
  • Gregory Broderick
  • Arthur L Burnett
  • Jeffrey D Campbell
  • Jonathan Clavell-Hernandez
  • Jessica Connor
  • Martin Gross
  • Ross Guillum
  • Amy I Guise
  • Georgios Hatzichristodoulou
  • Gerard D Henry
  • Tung-Chin Hsieh
  • Lawrence C Jenkins
  • Christopher Koprowski
  • Kook B Lee
  • Aaron Lentz
  • Ricardo M Munarriz
  • Daniar Osmonov
  • Shu Pan
  • Kevin Parikh
  • Sung Hun Park
  • Amir S Patel
  • Paul Perito
  • Hossein Sadeghi-Nejad
  • Maxime Sempels
  • Jay Simhan
  • Run Wang
  • Faysal A Yafi
  • Int. J. Impot. Res..2020 Mar;10.1038/s41443-020-0261-5. doi: 10.1038/s41443-020-0261-5.Epub 2020-03-20.

カメルーン産の食用・薬用キノコPleurotus tuber-regium(Agaricomycetes)の粗抽出物の抗真菌・抗菌活性の比較評価

Comparative Assessment of Antifungal and Antibacterial Activities of Crude Extracts of the King Tuber Culinary-Medicinal Mushroom, Pleurotus tuber-regium (Agaricomycetes) from Cameroon.
  • Blondo-Pascal Metsebing
  • Romuald Oba
  • Dominique Claude Mossebo
  • Thierry Youmbi Fonkui
  • Fabrice Tsigaing Tsigain
  • Marthe Carine Djuidje Fotsing
  • Tata Charlotte Mungoh
  • Derek Ntantoh Ndinteh
  • Int J Med Mushrooms.2020;22(4):359-366. 742ee6254aa2c7db,25f63c9a2c43158e. doi: 10.1615/IntJMedMushrooms.2020034178.

シグナル伝達型アダプター蛋白質-2は、造血ストレス時のB系統リンパ球の回復を遅延させる

Signal-transducing adaptor protein-2 delays recovery of B lineage lymphocytes during hematopoietic stress.
  • Michiko Ichii
  • Kenji Oritani
  • Jun Toda
  • Hideaki Saito
  • Henyun Shi
  • Hirohiko Shibayama
  • Daisuke Motooka
  • Yuichi Kitai
  • Ryuta Muromoto
  • Jun-Ichi Kashiwakura
  • Kodai Saitoh
  • Daisuke Okuzaki
  • Tadashi Matsuda
  • Yuzuru Kanakura
  • Haematologica.2020 Jan;haematol.2019.225573. doi: 10.3324/haematol.2019.225573.Epub 2020-01-23.

COVID-19入院患者の肺高血圧と右室病変

Pulmonary hypertension and right ventricular involvement in hospitalised patients with COVID-19.
  • Matteo Pagnesi
  • Luca Baldetti
  • Alessandro Beneduce
  • Francesco Calvo
  • Mario Gramegna
  • Vittorio Pazzanese
  • Giacomo Ingallina
  • Antonio Napolano
  • Renato Finazzi
  • Annalisa Ruggeri
  • Silvia Ajello
  • Giulio Melisurgo
  • Paolo Guido Camici
  • Paolo Scarpellini
  • Moreno Tresoldi
  • Giovanni Landoni
  • Fabio Ciceri
  • Anna Mara Scandroglio
  • Eustachio Agricola
  • Alberto Maria Cappelletti
  • Heart.2020 Jul;heartjnl-2020-317355. doi: 10.1136/heartjnl-2020-317355.Epub 2020-07-16.