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日本語AIでPubMedを検索

日本語AIでPubMedを検索

PubMedの提供する医学論文データベースを日本語で検索できます。AI(Deep Learning)を活用した機械翻訳エンジンにより、精度高く日本語へ翻訳された論文をご参照いただけます。

みんなが読んでいる論文

クルクミンによるGSK-3β阻害は、ヒト神経芽腫細胞において、TFEBの活性化と抗酸化活性を介してアミロイド生成を抑制します

GSK-3β inhibition by curcumin mitigates amyloidogenesis via TFEB activation and anti-oxidative Activity in human neuroblastoma cells.
  • Hyun-Chul Song
  • Yubing Chen
  • Yingqing Chen
  • Jeongmin Park
  • Min Zheng
  • Young-Joon Surh
  • Uh-Hyun Kim
  • Jeong Woo Park
  • Rina Yu
  • Hun Taeg Chung
  • Yeonsoo Joe
  • Free Radic. Res..2020 Jul;:1-39. doi: 10.1080/10715762.2020.1791843.Epub 2020-07-06.

慢性HBV感染症患者におけるB型肝炎表面抗原のウイルス特異的およびグローバルT細胞に対する効果

Effects of Hepatitis B Surface Antigen on Virus-specific and Global T Cells in Patients With Chronic HBV infection.
  • Nina Le Bert
  • Upkar S Gill
  • Michelle Hong
  • Kamini Kunasegaran
  • Damien Z M Tan
  • Raidah Ahmad
  • Yang Cheng
  • Charles-A Dutertre
  • Andreas Heinecke
  • Laura Rivino
  • Anthony Tan
  • Navjyot K Hansi
  • Min Zhang
  • Sujuan Xi
  • Yutian Chong
  • Stefan Pflanz
  • Evan W Newell
  • Patrick T F Kennedy
  • Antonio Bertoletti
  • Gastroenterology.2020 Apr;S0016-5085(20)30492-3. doi: 10.1053/j.gastro.2020.04.019.Epub 2020-04-14.

非骨髄芽腫性β-サラサラ血症マウスにおけるβ-サラサラ血症患者由来の遺伝的に補正されたiPSCの安全性と有効性

The safety and effectiveness of genetically corrected iPSCs derived from β-thalassaemia patients in nonmyeloablative β-thalassaemic mice.
  • Yexing Xian
  • Yingjun Xie
  • Bing Song
  • Zhanhui Ou
  • Shuming Ouyang
  • Yuhuan Xie
  • Yi Yang
  • Zeyu Xiong
  • Haoxian Li
  • Xiaofang Sun
  • Stem Cell Res Ther.2020 Jul;11(1):288. 10.1186/s13287-020-01765-w. doi: 10.1186/s13287-020-01765-w.Epub 2020-07-16.

脳微小透析研究のためのバイオマトリックス中の物理化学的特性と未結合画分に基づく中枢神経系薬剤候補の除外

Exclusion of unsuitable CNS drug candidates based on their physicochemical properties and unbound fractions in biomatrices for brain microdialysis investigations.
  • Qianwen Wang
  • Tianjing Ren
  • Jiajia Zhao
  • Chun-Ho Wong
  • H Y Edwin Chan
  • Zhong Zuo
  • J Pharm Biomed Anal.2020 Jan;178:112946. S0731-7085(19)30281-X. doi: 10.1016/j.jpba.2019.112946.Epub 2019-10-25.

Brachiaria brizanthaへのEnterolobium cyclocarpumポッドおよびGliricidia sepium飼料の添加が乾物分解、揮発性脂肪酸濃度、およびin vitroメタン生産に及ぼす影響

Effect of the addition of Enterolobium cyclocarpum pods and Gliricidia sepium forage to Brachiaria brizantha on dry matter degradation, volatile fatty acid concentration, and in vitro methane production.
  • Isabel Cristina Molina-Botero
  • Johanna Mazabel
  • Jeyder Arceo-Castillo
  • José Luis Urrea-Benítez
  • Leticia Olivera-Castillo
  • Rolando Barahona-Rosales
  • Ngonidzashe Chirinda
  • Juan Ku-Vera
  • Jacobo Arango
  • Trop Anim Health Prod.2020 Jul;10.1007/s11250-020-02324-4. doi: 10.1007/s11250-020-02324-4.Epub 2020-07-09.

TOR1AIP1-associated nuclear envelopathiesの表現型をさらに拡大した2つの新規症例

Two novel cases further expand the phenotype of TOR1AIP1-associated nuclear envelopathies.
  • Ivana Lessel
  • Mei-Jan Chen
  • Sabine Lüttgen
  • Florian Arndt
  • Sigrid Fuchs
  • Stefanie Meien
  • Holger Thiele
  • Julie R Jones
  • Brandon R Shaw
  • David K Crossman
  • Peter Nürnberg
  • Bruce R Korf
  • Christian Kubisch
  • Davor Lessel
  • Hum. Genet..2020 Apr;139(4):483-498. 10.1007/s00439-019-02105-6. doi: 10.1007/s00439-019-02105-6.Epub 2020-02-13.

リトアニアの IPV ワクチン接種児を対象とした 1 価経口 2 型サビンポリオワクチン接種後の免疫原性と安全性に関する無作為化第 4 相試験

A randomized phase 4 study of immunogenicity and safety following monovalent oral type 2 Sabin polio vaccine challenge in IPV-vaccinated children in Lithuania.
  • Ananda S Bandyopadhyay
  • Chris Gast
  • Elizabeth B Brickley
  • Ricardo Rüttimann
  • Ralf Clemens
  • M Steven Oberste
  • William C Weldon
  • Margaret E Ackerman
  • Ruth I Connor
  • Wendy F Wieland-Alter
  • Peter Wright
  • Vytautas Usonis
  • J. Infect. Dis..2020 Jul;jiaa390. doi: 10.1093/infdis/jiaa390.Epub 2020-07-04.

根管形成における交渉、グライドパス、プレフレアの手順が根管形成に与える影響-用語、基本概念、および系統的なレビュー

Influence of Negotiation, Glide Path, and Preflaring Procedures on Root Canal Shaping-Terminology, Basic Concepts, and a Systematic Review.
  • Gianluca Plotino
  • Venkateshbabu Nagendrababu
  • Frederic Bukiet
  • Nicola M Grande
  • Sajesh K Veettil
  • Gustavo De-Deus
  • Hany Mohamed Aly Ahmed
  • J Endod.2020 Jun;46(6):707-729. S0099-2399(20)30076-5. doi: 10.1016/j.joen.2020.01.023.Epub 2020-04-22.

骨粗鬆症性椎体圧迫骨折(OVCF)患者の治療における片側と両側の経皮的弯曲術の比較:システマティックレビューとメタアナリシス

Comparison of unilateral versus bilateral percutaneous kyphoplasty for the treatment of patients with osteoporosis vertebral compression fracture (OVCF): a systematic review and meta-analysis.
  • Xing Cheng
  • Hou-Qing Long
  • Jing-Hui Xu
  • Yang-Liang Huang
  • Fo-Bao Li
  • Eur Spine J.2016 11;25(11):3439-3449. 10.1007/s00586-016-4395-6. doi: 10.1007/s00586-016-4395-6.Epub 2016-01-27.

5αリダクターゼ阻害剤の共投与は、処方されたグルココルチコイドの有害な代謝作用を悪化させる

Co-administration of 5α-reductase inhibitors worsens the adverse metabolic effects of prescribed glucocorticoids.
  • Nantia Othonos
  • Thomas Marjot
  • Conor Woods
  • Jonathan M Hazlehurst
  • Nikolaos Nikolaou
  • Riccardo Pofi
  • Sarah White
  • Ilaria Bonaventura
  • Craig Webster
  • Joanne Duffy
  • Thomas Cornfield
  • Ahmad Moolla
  • Andrea M Isidori
  • Leanne Hodson
  • Jeremy W Tomlinson
  • J. Clin. Endocrinol. Metab..2020 Jun;dgaa408. doi: 10.1210/clinem/dgaa408.Epub 2020-06-27.

ルネッサンスへの準備:COVID-19パンデミック時の乳がんの治療と、ユニバーサル・ヘルスケア・システム内での日常的な外科的ケアへの安全な再浮上のための計画

Preparing for the renaissance: treating breast cancer during the COVID-19 pandemic and planning for a safe re-emergence to routine surgical care within a universal health care system.
  • D Berger-Richardson
  • G Ko
  • N J Look Hong
  • Curr Oncol.2020 06;27(3):163-168. conc-27-163. doi: 10.3747/co.27.6699.Epub 2020-06-01.

ソニックヘッジホッグ/Gli経路転写標的であるNeogenin-1のダウンレギュレーションは、基底細胞癌の攻撃性と関連している

Downregulation of the Sonic Hedgehog/Gli pathway transcriptional target Neogenin-1 is associated with basal cell carcinoma aggressiveness.
  • Bárbara S Casas
  • Christelle Adolphe
  • Pablo Lois
  • Nelson Navarrete
  • Natalia Solís
  • Eva Bustamante
  • Patricio Gac
  • Patricio Cabané
  • Ivan Gallegos
  • Brandon J Wainwright
  • Verónica Palma
  • Oncotarget.2017 Oct;8(48):84006-84018. 21061. doi: 10.18632/oncotarget.21061.Epub 2017-09-19.

心筋虚血が疑われる安定した外来患者におけるフローサイトメトリーに基づく血小板反応性の性差

Sex differences in flow cytometry-based platelet reactivity in stable outpatients suspected of myocardial ischemia.
  • Farahnaz Waissi
  • Mirthe Dekker
  • Ingrid E M Bank
  • Suzanne J A Korporaal
  • Rolf T Urbanus
  • Gert J de Borst
  • Gerard Pasterkamp
  • Asbjorn M Scholtens
  • Diederick E Grobbee
  • Arend Mosterd
  • Dominique P V de Kleijn
  • Leo Timmers
  • Res Pract Thromb Haemost.2020 Jul;4(5):879-885. RTH212344. doi: 10.1002/rth2.12344.Epub 2020-05-15.

一般的なバイオマーカーから導き出された有効な死亡率リスクスコアを用いて、退院後に病院関連の静脈血栓塞栓症を医療患者の間で予測する

Predicting postdischarge hospital-associated venous thromboembolism among medical patients using a validated mortality risk score derived from common biomarkers.
  • Lindsey Snyder
  • Scott M Stevens
  • Masarret Fazili
  • Emily L Wilson
  • James F Lloyd
  • Benjamin D Horne
  • Joseph Bledsoe
  • Scott C Woller
  • Res Pract Thromb Haemost.2020 Jul;4(5):872-878. RTH212343. doi: 10.1002/rth2.12343.Epub 2020-05-20.

ヤギにおける家畜化遺伝子の起源

The origin of domestication genes in goats.
  • Zhuqing Zheng
  • Xihong Wang
  • Ming Li
  • Yunjia Li
  • Zhirui Yang
  • Xiaolong Wang
  • Xiangyu Pan
  • Mian Gong
  • Yu Zhang
  • Yingwei Guo
  • Yu Wang
  • Jing Liu
  • Yudong Cai
  • Qiuming Chen
  • Moses Okpeku
  • Licia Colli
  • Dawei Cai
  • Kun Wang
  • Shisheng Huang
  • Tad S Sonstegard
  • Ali Esmailizadeh
  • Wenguang Zhang
  • Tingting Zhang
  • Yangbin Xu
  • Naiyi Xu
  • Yi Yang
  • Jianlin Han
  • Lei Chen
  • Joséphine Lesur
  • Kevin G Daly
  • Daniel G Bradley
  • Rasmus Heller
  • Guojie Zhang
  • Wen Wang
  • Yulin Chen
  • Yu Jiang
  • Sci Adv.2020 May;6(21):eaaz5216. aaz5216. doi: 10.1126/sciadv.aaz5216.Epub 2020-05-20.

コネクトベースのモデルは大うつ病性障害の初期症状改善を予測できる

Connectome-based models can predict early symptom improvement in major depressive disorder.
  • Yumeng Ju
  • Corey Horien
  • Wentao Chen
  • Weilong Guo
  • Xiaowen Lu
  • Jinrong Sun
  • Qiangli Dong
  • Bangshan Liu
  • Jin Liu
  • Danfeng Yan
  • Mi Wang
  • Liang Zhang
  • Hua Guo
  • Futao Zhao
  • Yan Zhang
  • Xilin Shen
  • R Todd Constable
  • Lingjiang Li
  • J Affect Disord.2020 Aug;273:442-452. S0165-0327(20)30620-0. doi: 10.1016/j.jad.2020.04.028.Epub 2020-05-11.

抗ミューレリアンホルモンと卵胞数は、POSEIDON群3および4の患者における最初の完全卵巣刺激サイクルの累積治療成績を予測する能力に違いがある

Anti-Müllerian hormone and antral follicle count differ in their ability to predict cumulative treatment outcomes of the first complete ovarian stimulation cycle in patients from POSEIDON groups 3 and 4.
  • Luxin Liu
  • Canquan Zhou
  • J. Obstet. Gynaecol. Res..2020 Jul;doi: 10.1111/jog.14269.Epub 2020-07-19.

経皮的冠動脈インターベンションを受けた中国人急性冠症候群患者に対するチカグレラーとクロピドグレルの有効性評価をデータマイニングと機械学習による決定木アプローチで行った

Efficacy assessment of ticagrelor versus clopidogrel in Chinese patients with acute coronary syndrome undergoing percutaneous coronary intervention by data mining and machine-learning decision tree approaches.
  • Ying Xue
  • Ziheng Hu
  • Yankang Jing
  • Hongyi Wu
  • Xiaoye Li
  • Junmei Wang
  • Amy Seybert
  • Xiangqun Xie
  • Qianzhou Lv
  • J Clin Pharm Ther.2020 Jul;doi: 10.1111/jcpt.13172.Epub 2020-07-06.

アンキリンリピートドメイン(R635X)の病原性NFKB2変異体は可変抗体欠損症を引き起こす

Pathogenic NFKB2 variant in the ankyrin repeat domain (R635X) causes a variable antibody deficiency.
  • Paul Tuijnenburg
  • Hana Lango Allen
  • Godelieve J de Bree
  • Sinisa Savic
  • Machiel H Jansen
  • Claire Stockdale
  • Ilenia Simeoni
  • Ineke J M Ten Berge
  • Ester M M van Leeuwen
  • James E Thaventhiran
  • Taco W Kuijpers
  • Clin. Immunol..2019 06;203:23-27. S1521-6616(18)30590-4. doi: 10.1016/j.clim.2019.03.010.Epub 2019-04-03.

日常診療における関節リウマチインパクト(RAID)の使用;DAS28寛解とアンメット患者報告アウトカムの同定

Use of rheumatoid arthritis impact of disease (RAID) in routine care; identification of DAS28 remission and unmet patient-reported outcomes.
  • Jatin Mistry
  • Mohammed Sharif
  • Amy Prideaux
  • Catherine Smith
  • Malama Sumbwanyambe
  • Margaret Sibley
  • Lewis Carpenter
  • Melissa Sweeney
  • Patrick Kiely
  • Rheumatol Adv Pract.2020;4(2):rkaa013. rkaa013. doi: 10.1093/rap/rkaa013.Epub 2020-04-27.

循環性腫瘍細胞を有するHER2非増幅型早期乳癌(EORTC 90091-10093、BIG 1-12、Treat CTC)に対するトラスツズマブと観察の比較:無作為化第II相試験

Trastuzumab versus observation for HER2 nonamplified early breast cancer with circulating tumor cells (EORTC 90091-10093, BIG 1-12, Treat CTC): a randomized phase II trial.
  • M Ignatiadis
  • S Litière
  • F Rothe
  • S Riethdorf
  • C Proudhon
  • T Fehm
  • K Aalders
  • H Forstbauer
  • P A Fasching
  • E Brain
  • P Vuylsteke
  • E Guardiola
  • R Lorenz
  • K Pantel
  • K Tryfonidis
  • W Janni
  • M Piccart
  • C Sotiriou
  • B Rack
  • J-Y Pierga
  • Ann. Oncol..2018 08;29(8):1777-1783. S0923-7534(19)34129-8. doi: 10.1093/annonc/mdy211.

内視鏡支援下顎切除術。手術手技と手術縁のコントロール

Endoscopic-assisted maxillectomy: Operative technique and control of surgical margins.
  • Alberto Deganello
  • Marco Ferrari
  • Alberto Paderno
  • Mario Turri-Zanoni
  • Alberto Schreiber
  • Davide Mattavelli
  • Alperen Vural
  • Vittorio Rampinelli
  • Alberto Daniele Arosio
  • Alessandro Ioppi
  • Mario Cherubino
  • Paolo Castelnuovo
  • Piero Nicolai
  • Paolo Battaglia
  • Oral Oncol..2019 06;93:29-38. S1368-8375(19)30102-2. doi: 10.1016/j.oraloncology.2019.04.002.Epub 2019-04-11.

マングローブクラブGoniopsis cruentata(Brachyura, Grapsidae)のエラにおける(Na, K)-ATPase活性の生化学的特性とマグネシウムによるアロステリックな調節

Biochemical Characterization and Allosteric Modulation by Magnesium of (Na, K)-ATPase Activity in the Gills of the Red Mangrove Crab Goniopsis cruentata (Brachyura, Grapsidae).
  • Cintya M Moraes
  • Malson N Lucena
  • Daniela P Garçon
  • Marcelo R Pinto
  • Leonardo M Fabri
  • Rogério O Faleiros
  • Carlos F L Fontes
  • John C McNamara
  • Francisco A Leone
  • J. Membr. Biol..2020 Jun;253(3):229-245. 10.1007/s00232-020-00120-7. doi: 10.1007/s00232-020-00120-7.Epub 2020-05-22.

STING依存性パラクリニーは抗ミトックス治療に応答して乳房腫瘍のアポトーシスプライミングを形成する

STING-dependent paracriny shapes apoptotic priming of breast tumors in response to anti-mitotic treatment.
  • Steven Lohard
  • Nathalie Bourgeois
  • Laurent Maillet
  • Fabien Gautier
  • Aurélie Fétiveau
  • Hamza Lasla
  • Frédérique Nguyen
  • Céline Vuillier
  • Alison Dumont
  • Agnès Moreau-Aubry
  • Morgane Frapin
  • Laurent David
  • Delphine Loussouarn
  • Olivier Kerdraon
  • Mario Campone
  • Pascal Jézéquel
  • Philippe P Juin
  • Sophie Barillé-Nion
  • Nat Commun.2020 01;11(1):259. 10.1038/s41467-019-13689-y. doi: 10.1038/s41467-019-13689-y.Epub 2020-01-14.