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日本語AIでPubMedを検索

日本語AIでPubMedを検索

PubMedの提供する医学論文データベースを日本語で検索できます。AI(Deep Learning)を活用した機械翻訳エンジンにより、精度高く日本語へ翻訳された論文をご参照いただけます。

みんなが読んでいる論文

輸入ネクタリンの木から新たなルテウイルスが検出された。入国後検疫におけるメタゲノミクスの導入を提案するためのケーススタディ

Detection of a New Luteovirus in Imported Nectarine Trees: A Case Study to Propose Adoption of Metagenomics in Post-Entry Quarantine.
  • Sudeep Bag
  • Maher Al Rwahnih
  • Ashley Li
  • Asaul Gonzalez
  • Adib Rowhani
  • Jerry K Uyemoto
  • Mysore R Sudarshana
  • Phytopathology.2015 Jun;105(6):840-6. doi: 10.1094/PHYTO-09-14-0262-R.Epub 2015-05-29.

生物学的および合成標的治療を受けたリウマチ性疾患患者におけるCOVID-19の臨床的特徴と転帰

Clinical features and outcomes of COVID-19 in patients with rheumatic diseases treated with biological and synthetic targeted therapies.
  • Carlos Sanchez-Piedra
  • Cesar Diaz-Torne
  • Javier Manero
  • José M Pego-Reigosa
  • Íñigo Rúa-Figueroa
  • Miguel A Gonzalez-Gay
  • Juan Gomez-Reino
  • Jose M Alvaro-Gracia
  • Ann. Rheum. Dis..2020 07;79(7):988-990. annrheumdis-2020-217948. doi: 10.1136/annrheumdis-2020-217948.Epub 2020-06-05.

腎移植臓器移植患者に対するビタミンK:血管硬化の調査(ViKTORIES):無作為化比較試験の研究根拠とプロトコール

Vitamin K for kidney transplant organ recipients: investigating vessel stiffness (ViKTORIES): study rationale and protocol of a randomised controlled trial.
  • Jennifer Susan Lees
  • Kenneth Mangion
  • Elaine Rutherford
  • Miles D Witham
  • Rosemary Woodward
  • Giles Roditi
  • Tracey Hopkins
  • Katriona Brooksbank
  • Alan G Jardine
  • Patrick B Mark
  • Open Heart.2020 Jul;7(2). e001070. doi: 10.1136/openhrt-2019-001070.

Δ9-テトラヒドロカンナビノール(THC)ポストブドウ球菌性腸毒素B曝露の投与は、急性呼吸窮迫症候群と毒性からマウスを保護する

Administration of Δ9-Tetrahydrocannabinol (THC) Post-Staphylococcal Enterotoxin B Exposure Protects Mice From Acute Respiratory Distress Syndrome and Toxicity.
  • Amira Mohammed
  • Hasan Alghetaa
  • Muthanna Sultan
  • Narendra P Singh
  • Prakash Nagarkatti
  • Mitzi Nagarkatti
  • Front Pharmacol.2020;11:893. doi: 10.3389/fphar.2020.00893.Epub 2020-06-16.

標準的な接線放射線場では、乳腺内リンパ節への付随的なカバレッジは得られない

Standard Tangential Radiation Fields Do Not Provide Incidental Coverage to the Internal Mammary Nodes.
  • Gokoulakrichenane Loganadane
  • Megan Kassick
  • Benjamin H Kann
  • Melissa R Young
  • Christin A Knowlton
  • Suzanne B Evans
  • Susan A Higgins
  • Yazid Belkacemi
  • Mary Potenziani
  • Nicholas Saltmarsh
  • Lynn D Wilson
  • Meena S Moran
  • Pract Radiat Oncol.2020 Jan - Feb;10(1):21-28. S1879-8500(19)30226-7. doi: 10.1016/j.prro.2019.07.014.Epub 2019-08-05.

ゾレドロン酸逐次投与は、3年未満のデノスマブ治療の中止によるデメリットを回避できる可能性がある

Zoledronic acid sequential therapy could avoid disadvantages due to the discontinuation of less than 3-year denosumab treatment.
  • Hideomi Kondo
  • Nobukazu Okimoto
  • Toru Yoshioka
  • Shojiro Akahoshi
  • Yoshifumi Fuse
  • Takayuki Ogawa
  • Yuichi Okazaki
  • Yuji Katae
  • Manabu Tsukamoto
  • Yoshiaki Yamanaka
  • Makoto Kawasaki
  • Akinori Sakai
  • J. Bone Miner. Metab..2020 Jul;10.1007/s00774-020-01126-w. doi: 10.1007/s00774-020-01126-w.Epub 2020-07-12.

ジャガイモのアピラーゼの阻害に植物由来のカルコンのスクリーニング。健康における潜在的なタンパク質バイオテクノロジーのアプリケーション

Screening of plant derived chalcones on the inhibition of potato apyrase: Potential protein biotechnological applications in health.
  • Priscila Silva Grijó Farani
  • Danielle Gomes Marconato
  • Nayara Braga Emídio
  • Vinícius R D Pereira
  • Ismael J Alves Junior
  • Lígia S da Silveira
  • Mara R C Couri
  • Eveline Gomes Vasconcelos
  • William Castro Borges
  • Ademar Alves Silva Filho
  • Priscila de Faria-Pinto
  • Int. J. Biol. Macromol..2020 Jul;S0141-8130(20)33829-0. doi: 10.1016/j.ijbiomac.2020.07.081.Epub 2020-07-11.

集団遺伝学を用いて、大環状ラクトン抵抗性の状態と地域の両方に基づいてDirofilaria immitisの関連性を検討する

Using population genetics to examine relationships of Dirofilaria immitis based on both macrocyclic lactone-resistance status and geography.
  • Julie Sanchez
  • Guha Dharmarajan
  • Melissa M George
  • Cassan Pulaski
  • Adrian J Wolstenholme
  • John S Gilleard
  • Ray M Kaplan
  • Vet. Parasitol..2020 May;283:109125. S0304-4017(20)30105-9. doi: 10.1016/j.vetpar.2020.109125.Epub 2020-05-23.

前十字靭帯再建時のハムストリング自家移植のAllograft Augmentation of Hamstring Autograft Results in Equivalent Outcomes to Autograft Alone

Allograft Augmentation of Hamstring Autograft in Anterior Cruciate Ligament Reconstruction Results in Equivalent Outcomes to Autograft Alone.
  • Allison J Rao
  • David M Macknet
  • Casey R Stuhlman
  • Nicholas C Yeatts
  • David P Trofa
  • Susan M Odum
  • Bryan M Saltzman
  • James E Fleischli
  • Arthroscopy.2020 Jul;S0749-8063(20)30603-4. doi: 10.1016/j.arthro.2020.07.010.Epub 2020-07-14.

高尿酸血症を有する5/6腎摘出術モデルにおけるキサンチンオキシダーゼ阻害薬フェブキソスタットの心腎保護効果

Cardio-renal protective effect of the xanthine oxidase inhibitor febuxostat in the 5/6 nephrectomy model with hyperuricemia.
  • Hiroki Omizo
  • Yoshifuru Tamura
  • Chikayuki Morimoto
  • Masaki Ueno
  • Yuto Hayama
  • Emiko Kuribayashi-Okuma
  • Shunya Uchida
  • Shigeru Shibata
  • Sci Rep.2020 Jun;10(1):9326. 10.1038/s41598-020-65706-6. doi: 10.1038/s41598-020-65706-6.Epub 2020-06-09.

柑橘類の木におけるクロステロウイルス、バッドナウイルス、マンダリウイルスと黄龍ビン菌の同時検出のためのマルチプレックスポリメラーゼ連鎖反応法の開発(英文

Development of multiplex polymerase chain reaction assay for simultaneous detection of clostero-, badna- and mandari-viruses along with huanglongbing bacterium in citrus trees.
  • Ram Prasnna Meena
  • V K Baranwal
  • J. Virol. Methods.2016 09;235:58-64. S0166-0934(16)30251-8. doi: 10.1016/j.jviromet.2016.05.012.Epub 2016-05-18.

FZD10 抗体共役リポソームをベースとした制御された 5-FU 投与の大腸がん In vitro モデルでの有効性

Effectiveness of a Controlled 5-FU Delivery Based on FZD10 Antibody-Conjugated Liposomes in Colorectal Cancer In vitro Models.
  • Maria Principia Scavo
  • Annalisa Cutrignelli
  • Nicoletta Depalo
  • Elisabetta Fanizza
  • Valentino Laquintana
  • Giampietro Gasparini
  • Gianluigi Giannelli
  • Nunzio Denora
  • Pharmaceutics.2020 Jul;12(7). E650. doi: 10.3390/pharmaceutics12070650.Epub 2020-07-10.

免疫療法を受けた進行Nsclcにおける治療効果と生存率の予測因子としてのF-FDGペットパラメータとラジオミクス特徴の解析

F-FDG Pet Parameters and Radiomics Features Analysis in Advanced Nsclc Treated with Immunotherapy as Predictors of Therapy Response and Survival.
  • Giulia Polverari
  • Francesco Ceci
  • Valentina Bertaglia
  • Maria Lucia Reale
  • Osvaldo Rampado
  • Elena Gallio
  • Roberto Passera
  • Virginia Liberini
  • Paola Scapoli
  • Vincenzo Arena
  • Manuela Racca
  • Andrea Veltri
  • Silvia Novello
  • Désirée Deandreis
  • Cancers (Basel).2020 May;12(5). E1163. doi: 10.3390/cancers12051163.Epub 2020-05-05.

第9肋間静脈と第10肋間静脈を介したアジーゴス静脈への超音波ガイド下二重中心静脈アクセス

Ultrasound-guided double central venous access for azygos vein via the ninth and tenth intercostal veins.
  • Koichiro Yoshimaru
  • Toshiharu Matsuura
  • Yasuyuki Uchida
  • Keisuke Kajihara
  • Yukihiro Toriigahara
  • Yuki Kawano
  • Takuya Kondo
  • Yoshiaki Takahashi
  • Wakato Matsuoka
  • Noriyuki Kaku
  • Jun Maki
  • Tomoaki Taguchi
  • J Vasc Access.2020 Jun;:1129729820937133. doi: 10.1177/1129729820937133.Epub 2020-06-30.

近位部に多孔質コーティングを施したセメントレスの湾曲したショートステムの肩甲骨プロテーゼ:臨床的な相関関係を伴う2~5年後の放射線学的追跡調査でのイングロウ特性

Cementless curved short stem shoulder prostheses with a proximal porous coating: ingrowth properties at 2-5 years of radiological follow-up with clinical correlation.
  • Benjamin D Kleim
  • Christina Garving
  • Ulrich H Brunner
  • J Shoulder Elbow Surg.2020 Jun;S1058-2746(20)30236-6. doi: 10.1016/j.jse.2020.02.025.Epub 2020-06-09.

ブラジル・リオデジャネイロの献血者における抗SARS-CoV-2の血清有病率

Seroprevalence of anti-SARS-CoV-2 among blood donors in Rio de Janeiro, Brazil.
  • Luiz Amorim Filho
  • Célia Landmann Szwarcwald
  • Sheila de Oliveira Garcia Mateos
  • Antonio Carlos Monteiro Ponce de Leon
  • Roberto de Andrade Medronho
  • Valdiléa Gonçalves Veloso
  • Josiane Iole França Lopes
  • Luis Cristovão de Moraes Sobrino Porto
  • Alexandre Chieppe
  • Guilherme Loureiro Werneck
  • Rev Saude Publica.2020;54:69. S0034-89102020000100251. doi: 10.11606/s1518-8787.2020054002643.Epub 2020-07-06.

末梢性T細胞リンパ腫における自己幹細胞移植:血液CD34細胞のより良い動員は生存率の改善と関連している

Autologous stem cell transplantation in peripheral T-cell lymphoma: better mobilization of blood CD34 cells is associated with improved survival.
  • Anu Partanen
  • Antti Turunen
  • Jaakko Valtola
  • Marja Pyörälä
  • Kaija Vasala
  • Outi Kuittinen
  • Hanne Kuitunen
  • Karri Penttilä
  • Taru Kuittinen
  • Pentti Mäntymaa
  • Jukka Pelkonen
  • Ville Varmavuo
  • Esa Jantunen
  • Leuk. Lymphoma.2020 Jul;:1-3. doi: 10.1080/10428194.2020.1789629.Epub 2020-07-10.

グルタミン拮抗薬JHU-083は海馬の異常なグルタミナーゼ活性を正常化し、APOE4マウスの認知機能を改善する

Glutamine Antagonist JHU-083 Normalizes Aberrant Hippocampal Glutaminase Activity and Improves Cognition in APOE4 Mice.
  • Kristen R Hollinger
  • Xiaolei Zhu
  • Elizabeth S Khoury
  • Ajit G Thomas
  • Kevin Liaw
  • Carolyn Tallon
  • Ying Wu
  • Eva Prchalova
  • Atsushi Kamiya
  • Camilo Rojas
  • Sujatha Kannan
  • Barbara S Slusher
  • J. Alzheimers Dis..2020 Jul;JAD190588. doi: 10.3233/JAD-190588.Epub 2020-07-16.

製薬分野における溶融堆積モデリング(FDM)3Dプリンティングのエスカレーションについてのグラフィカルなレビュー

A graphical review on the escalation of fused deposition modeling (FDM) 3D printing in the pharmaceutical field.
  • Alice Melocchi
  • Marco Uboldi
  • Matteo Cerea
  • Anastasia Foppoli
  • Alessandra Maroni
  • Saliha Moutaharrik
  • Luca Palugan
  • Lucia Zema
  • Andrea Gazzaniga
  • J Pharm Sci.2020 Jul;S0022-3549(20)30377-4. doi: 10.1016/j.xphs.2020.07.011.Epub 2020-07-14.

顔面にきびを持つ被験者を対象としたクラスコテロン0.1%、0.5%、および1%の外用クリームを評価する第2b相、無作為化、二重盲検、車両対照、用量エスカレーション試験

A Phase 2b, Randomized, Double-Blind Vehicle Controlled, Dose Escalation Study Evaluating Clascoterone 0.1%, 0.5%, and 1% Topical Cream in Subjects With Facial Acne
  • Alessandro Mazzetti
  • Luigi Moro
  • Mara Gerloni
  • Martina Cartwright
  • J Drugs Dermatol.2019 Jun;18(6):570. S1545961619P0570X.

異なるタイプの病院で働く理学療法士・作業療法士におけるバーンアウト症候群と業務関連ストレス。どのグループが最も脆弱なのか?

Burnout Syndrome and Work-Related Stress in Physical and Occupational Therapists Working in Different Types of Hospitals: Which Group Is the Most Vulnerable?
  • Ju-Hyun Kim
  • Ae-Ryoung Kim
  • Myung-Gwan Kim
  • Chul-Hyun Kim
  • Ki-Hoon Lee
  • Donghwi Park
  • Jong-Moon Hwang
  • Int J Environ Res Public Health.2020 Jul;17(14). E5001. doi: 10.3390/ijerph17145001.Epub 2020-07-11.

生分解性ポリブチレンサクシネート及び非生分解性ポリ塩化ビニルマイクロプラスチックのアナモックス汚泥への影響性能評価,抑制効果,メタゲノム解析

Influence of biodegradable polybutylene succinate and non-biodegradable polyvinyl chloride microplastics on anammox sludge: Performance evaluation, suppression effect and metagenomic analysis.
  • Linqin Tang
  • Chengyuan Su
  • Yu Chen
  • Yunchuan Xian
  • Xinyue Hui
  • Ziyu Ye
  • Menglin Chen
  • Fenghua Zhu
  • He Zhong
  • J. Hazard. Mater..2020 Jun;401:123337. S0304-3894(20)31326-1. doi: 10.1016/j.jhazmat.2020.123337.Epub 2020-06-30.

スリランカにおける長い沈黙の後のメリオイドーシス:診断における環境的危険性とジレンマ、回復と13年間の長期追跡調査:症例報告

Melioidosis after a long silence in Sri Lanka: an environmental hazard and dilemma in diagnosis, with recovery and longitudinal follow-up for 13 years: a case report.
  • Manoji M K Pathirage
  • Senanayake A M Kularatne
  • Kosala G Weerakoon
  • J Med Case Rep.2020 Apr;14(1):50. 10.1186/s13256-020-02372-2. doi: 10.1186/s13256-020-02372-2.Epub 2020-04-18.

アデノウイルスベクターを用いた腫瘍新生血管新生へのターゲティングにより、播種性新生物病変に対する有効ながん遺伝子治療を実現する

Targeting Tumor Neoangiogenesis via Targeted Adenoviral Vector to Achieve Effective Cancer Gene Therapy for Disseminated Neoplastic Disease.
  • Myungeun Lee
  • Zhi Hong Lu
  • Jie Li
  • Elena A Kashentseva
  • Igor P Dmitriev
  • Samir A Mendonca
  • David T Curiel
  • Mol. Cancer Ther..2020 03;19(3):966-971. 1535-7163.MCT-19-0768. doi: 10.1158/1535-7163.MCT-19-0768.Epub 2020-01-06.

Agents Intervening against Delirium in the Intensive Care Unit Trial(AID-ICU試験)。詳細な統計解析計画

The Agents Intervening against Delirium in the Intensive Care Unit Trial (AID-ICU trial): A detailed statistical analysis plan.
  • Nina Andersen-Ranberg
  • Lone M Poulsen
  • Anders Perner
  • Jørn Wetterslev
  • Ole Mathiesen
  • Camilla B Mortensen
  • Stine Estrup
  • Bjørn H Ebdrup
  • Johanna Hästbacka
  • Giuseppe Citerio
  • Jesus Caballero
  • Matthew P G Morgan
  • Marie Oxenbøll-Collet
  • Sven-Olaf Weber
  • Anne Sofie Andreasen
  • Morten H Bestle
  • Helle B S Pedersen
  • Louise G Nielsen
  • Bülent Uslu
  • Troels B Jensen
  • Carsten Thee
  • Nilanjan Dey
  • Theis Lange
  • Acta Anaesthesiol Scand.2020 Jun;doi: 10.1111/aas.13661.Epub 2020-06-27.

近接-指数関数的ハイブリダイゼーション連鎖反応(PEHCR)とその応用による生細胞上の膜タンパク質-タンパク質相互作用の非破壊分析

A proximity-exponential hybridization chain reaction (PEHCR) and its application for nondestructive analysis of membrane protein-protein interactions on living cells.
  • Dongsheng Mao
  • Tianshu Chen
  • Xiaohao Liu
  • Lingjie Ren
  • Chang Feng
  • Guifang Chen
  • Anal. Chim. Acta.2020 Aug;1125:8-18. S0003-2670(20)30559-6. doi: 10.1016/j.aca.2020.05.024.Epub 2020-05-14.

うつ病リスクのある家族におけるうつ病症状の予測。後方脳波αと宗教・スピリチュアリティの相互関係

Predicting Depression Symptoms in Families at Risk for Depression: Interrelations of Posterior EEG Alpha and Religion/Spirituality.
  • Lidia Y X Panier
  • Gerard E Bruder
  • Connie Svob
  • Priya Wickramaratne
  • Marc J Gameroff
  • Myrna M Weissman
  • Craig E Tenke
  • Jürgen Kayser
  • J Affect Disord.2020 Sep;274:969-976. S0165-0327(20)30233-0. doi: 10.1016/j.jad.2020.05.084.Epub 2020-05-27.

トリパノソーマにおけるミトコンドリアRNA処理のレクシスと文法

Lexis and Grammar of Mitochondrial RNA Processing in Trypanosomes.
  • Inna Aphasizheva
  • Juan Alfonzo
  • Jason Carnes
  • Igor Cestari
  • Jorge Cruz-Reyes
  • H Ulrich Göringer
  • Stephen Hajduk
  • Julius Lukeš
  • Susan Madison-Antenucci
  • Dmitri A Maslov
  • Suzanne M McDermott
  • Torsten Ochsenreiter
  • Laurie K Read
  • Reza Salavati
  • Achim Schnaufer
  • André Schneider
  • Larry Simpson
  • Kenneth Stuart
  • Vyacheslav Yurchenko
  • Z Hong Zhou
  • Alena Zíková
  • Liye Zhang
  • Sara Zimmer
  • Ruslan Aphasizhev
  • Trends Parasitol..2020 Apr;36(4):337-355. S1471-4922(20)30016-7. doi: 10.1016/j.pt.2020.01.006.Epub 2020-02-28.

ベトナムのフルーツコウモリから分離された新規アルファヘルペスウイルスの特性評価

Characterization of a novel alphaherpesvirus isolated from the fruit bat , in Viet Nam.
  • Takuya Inagaki
  • Souichi Yamada
  • Hikaru Fujii
  • Tomoki Yoshikawa
  • Miho Shibamura
  • Shizuko Harada
  • Shuetsu Fukushi
  • Mai Quynh Le
  • Co Thach Nguyen
  • Thi Thu Thuy Nguyen
  • Thanh Thuy Nguyen
  • Thanh Thuy Nguyen
  • Van Tay Quach
  • Vu Dinh Thong
  • Kazuki Mori
  • Michihito Sasaki
  • Agus Setiyono
  • Ekowati Handharyani
  • Haruko Takeyama
  • Futoshi Hasebe
  • Masayuki Saijo
  • J. Virol..2020 Jul;JVI.00673-20. doi: 10.1128/JVI.00673-20.Epub 2020-07-15.

軟部組織肉腫の肝臓への転移。病院ベースのがん登録からの歴史的コホート研究

Metastases of soft tissue sarcoma to the liver: A Historical Cohort Study from a Hospital-based Cancer Registry.
  • Masanori Okamoto
  • Masatake Matsuoka
  • Tamotsu Soma
  • Ryuta Arai
  • Hidenori Kato
  • Toru Harabayashi
  • Hirohumi Adachi
  • Toshiki Shinohara
  • Tamotsu Sagawa
  • Noriaki Nishiyama
  • Toshikazu Nambu
  • Wataru Sakai
  • Hiroaki Suzuki
  • Hiroyuki Kato
  • Hiroaki Hiraga
  • Cancer Med.2020 Jul;doi: 10.1002/cam4.3304.Epub 2020-07-10.

心血管磁気共鳴画像上の右室機能の低下は、ファロー四徴症の子宮胎盤機能障害と関連している

Reduced right ventricular function on cardiovascular magnetic resonance imaging is associated with uteroplacental impairment in tetralogy of Fallot.
  • Anne S Siegmund
  • Tineke P Willems
  • Petronella G Pieper
  • Caterina M Bilardo
  • Thomas M Gorter
  • Berto J Bouma
  • Monique R M Jongbloed
  • Gertjan Tj Sieswerda
  • Jolien W Roos-Hesselink
  • Arie P J van Dijk
  • Dirk J van Veldhuisen
  • Michael G Dickinson
  • J Cardiovasc Magn Reson.2020 Jul;22(1):52. 10.1186/s12968-020-00645-9. doi: 10.1186/s12968-020-00645-9.Epub 2020-07-16.

非小児結節性大腸病変に対する水中内視鏡的粘膜切除術。将来性のあるシングルアームの研究

UNDERWATER ENDOSCOPIC MUCOSAL RESECTION FOR NON-PEDUNCULATED COLORECTAL LESIONS. A PROSPECTIVE SINGLE-ARM STUDY.
  • Luciano Lenz
  • Bruno Martins
  • Fabio Shiguehisa Kawaguti
  • Alexandre Tellian
  • Caterina Maria Pia Simoni Pennachi
  • Mauricio Sorbello
  • Carla Gusmon
  • Gustavo Andrade de Paulo
  • Ricardo Uemura
  • Sebastian Geiger
  • Marcelo Simas de Lima
  • Adriana Safatle-Ribeiro
  • Elisa Baba
  • Claudio Lyoiti Hashimoto
  • Fauze Maluf-Filho
  • Ulysses Ribeiro
  • Arq Gastroenterol.2020 Apr-Jun;57(2):193-197. S0004-28032020000200193. doi: 10.1590/S0004-2803.202000000-37.

α-リノレン酸は、ツイスト1発現を減衰させ、ツイスト1介在性上皮間葉転換を抑制することで、ヒトトリプルネガティブ乳がん細胞の遊走を阻害する

α-Linolenic acid inhibits the migration of human triple-negative breast cancer cells by attenuating twist1 expression and suppressing twist1-mediated epithelial-mesenchymal transition.
  • Shih-Chung Wang
  • Hai-Lun Sun
  • Yi-Hsuan Hsu
  • Shu-Hui Liu
  • Chong-Kuei Lii
  • Chia-Han Tsai
  • Kai-Li Liu
  • Chin-Shiu Huang
  • Chien-Chun Li
  • Biochem. Pharmacol..2020 Jul;:114152. S0006-2952(20)30388-9. doi: 10.1016/j.bcp.2020.114152.Epub 2020-07-14.

CpGをコーティングしたプルシアンブルーナノ粒子をベースとした光熱療法と抗CTLA-4免疫チェックポイント遮断を組み合わせることで、神経芽腫に対する強力な休薬効果が誘発された

CpG-coated Prussian blue nanoparticles-based photothermal therapy combined with anti-CTLA-4 immune checkpoint blockade triggers a robust abscopal effect against neuroblastoma.
  • Juliana Cano-Mejia
  • Anshi Shukla
  • Debbie K Ledezma
  • Erica Palmer
  • Alejandro Villagra
  • Rohan Fernandes
  • Transl Oncol.2020 Jul;13(10):100823. S1936-5233(20)30315-6. doi: 10.1016/j.tranon.2020.100823.Epub 2020-07-08.

殺乳酸菌Lactobacillus casei DK128のTヘルパー1型免疫応答の増強に対するアジュバント効果と正常マウスおよびCD4欠損マウスにおけるインフルエンザワクチン接種の有効性について検討した

Adjuvant effects of killed Lactobacillus casei DK128 on enhancing T helper type 1 immune responses and the efficacy of influenza vaccination in normal and CD4-deficient mice.
  • Yu-Jin Jung
  • Ki-Hye Kim
  • Eun-Ju Ko
  • Youri Lee
  • Min-Chul Kim
  • Young-Tae Lee
  • Cheol-Hyun Kim
  • Subbiah Jeeva
  • Bo Ryoung Park
  • Sang-Moo Kang
  • Vaccine.2020 Jul;S0264-410X(20)30878-1. doi: 10.1016/j.vaccine.2020.06.075.Epub 2020-07-13.

勃起不全高齢ラットを対象としたロサルタン投与による体細胞のアポトーシスと酸化ストレスの抑制による勃起機能の回復

Restoration of erectile function by suppression of corporal apoptosis and oxidative stress with losartan in aged rats with erectile dysfunction.
  • Yi Wang
  • Yamin Wang
  • Rong Cong
  • Ye Tian
  • Chen Chen
  • Yichun Wang
  • Qijie Zhang
  • Xiang Zhou
  • Chengjian Ji
  • Xianghu Meng
  • Ninghong Song
  • Andrology.2020 May;8(3):769-779. doi: 10.1111/andr.12757.Epub 2020-02-03.

大規模ゲノムアソシエーション解析により、複数の圃場環境下で縞さび病抵抗性を付与する原因遺伝子候補を同定した

A large-scale genomic association analysis identifies the candidate causal genes conferring stripe rust resistance under multiple field environments.
  • Jianhui Wu
  • Rui Yu
  • Haiying Wang
  • Cai'e Zhou
  • Shuo Huang
  • Hanxuan Jiao
  • Shizhou Yu
  • Xiaojun Nie
  • Qilin Wang
  • Shengjie Liu
  • Song Weining
  • R P Singh
  • Sridhar Bhavani
  • Zhensheng Kang
  • Dejun Han
  • Qingdong Zeng
  • Plant Biotechnol. J..2020 Jul;doi: 10.1111/pbi.13452.Epub 2020-07-17.

世界的な脳神経外科の不公平に対処するための研究文献と医療システムレベルの取り組みとの間の結束: スコーピングレビュー

Cohesion between Research Literature and Health System Level Efforts to Address Global Neurosurgical Inequity: a scoping review.
  • Edward I Ham
  • Jeongyoon Kim
  • Ulrick Sidney
  • Jean Wilguens Lartigue
  • Saksham Gupta
  • Ignatius N Esene
  • Kee B Park
  • World Neurosurg.2020 Jul;S1878-8750(20)31515-1. doi: 10.1016/j.wneu.2020.06.237.Epub 2020-07-13.

米国の民間保険者集団における原発性副甲状腺機能亢進症の未治療。手術ガイドラインの拡大にもかかわらず、副甲状腺摘出術の利用率が低下している

Undertreatment of primary hyperparathyroidism in a privately insured US population: Decreasing utilization of parathyroidectomy despite expanding surgical guidelines.
  • Carolyn D Seib
  • Tong Meng
  • Insoo Suh
  • Robin M Cisco
  • Dana T Lin
  • Arden M Morris
  • Amber W Trickey
  • Electron Kebebew
  • Surgery.2020 Jul;S0039-6060(20)30289-0. doi: 10.1016/j.surg.2020.04.066.Epub 2020-07-09.

アリサルタン・イソプロキシルは本態性高血圧患者の内皮機能と血管障害を改善する。本態性高血圧症患者におけるアリサルタン・イソプロキシルの血管内皮機能改善効果:単施設、オープンラベル、無作為化対照試験

Allisartan Isoproxil Improves Endothelial Function and Vascular Damage in Patients with Essential Hypertension: A Single-Center, Open-Label, Randomized Controlled Trial.
  • Gaoxing Zhang
  • Yongqiang Fan
  • Yumin Qiu
  • Zhe Zhou
  • Jianning Zhang
  • Zhichao Wang
  • Yuanya Liu
  • Xing Liu
  • Jun Tao
  • Adv Ther.2020 Aug;37(8):3551-3561. 10.1007/s12325-020-01413-y. doi: 10.1007/s12325-020-01413-y.Epub 2020-06-24.

大メコン亜地域における抗マラリア薬耐性の分子疫学:観察研究

Molecular epidemiology of resistance to antimalarial drugs in the Greater Mekong subregion: an observational study.
  • Mallika Imwong
  • Mehul Dhorda
  • Kyaw Myo Tun
  • Aung Myint Thu
  • Aung Pyae Phyo
  • Stephane Proux
  • Kanokon Suwannasin
  • Chanon Kunasol
  • Suttipat Srisutham
  • Jureeporn Duanguppama
  • Ranitha Vongpromek
  • Cholrawee Promnarate
  • Aungkana Saejeng
  • Nardlada Khantikul
  • Rungniran Sugaram
  • Supinya Thanapongpichat
  • Nongyao Sawangjaroen
  • Kreepol Sutawong
  • Kay Thwe Han
  • Ye Htut
  • Khin Linn
  • Aye Aye Win
  • Tin M Hlaing
  • Rob W van der Pluijm
  • Mayfong Mayxay
  • Tiengkham Pongvongsa
  • Koukeo Phommasone
  • Rupam Tripura
  • Thomas J Peto
  • Lorenz von Seidlein
  • Chea Nguon
  • Dysoley Lek
  • Xin Hui S Chan
  • Huy Rekol
  • Rithea Leang
  • Cheah Huch
  • Dominic P Kwiatkowski
  • Olivo Miotto
  • Elizabeth A Ashley
  • Myat Phone Kyaw
  • Sasithon Pukrittayakamee
  • Nicholas P J Day
  • Arjen M Dondorp
  • Frank M Smithuis
  • Francois H Nosten
  • Nicholas J White
  • Lancet Infect Dis.2020 Jul;S1473-3099(20)30228-0. doi: 10.1016/S1473-3099(20)30228-0.Epub 2020-07-14.

進行膵癌患者に対するナブパクリタキセル+ゲムシタビン療法後のセカンドライン化学療法におけるS-1の有効性

Efficacy of S-1 in second-line chemotherapy after nab-paclitaxel plus gemcitabine for patients with advanced pancreatic cancer.
  • Kiyotsugu Iede
  • Terumasa Yamada
  • Ryo Kato
  • Masami Ueda
  • Yujiro Tsuda
  • Shinsuke Nakashima
  • Katsuya Ohta
  • Jin Matsuyama
  • Masakazu Ikenaga
  • Shusei Tominaga
  • Cancer Rep (Hoboken).2020 Apr;3(2):e1215. doi: 10.1002/cnr2.1215.Epub 2019-08-28.