あなたは歯科・医療関係者ですか?

WHITE CROSSは、歯科・医療現場で働く方を対象に、良質な歯科医療情報の提供を目的とした会員制サイトです。

日本語AIでPubMedを検索

日本語AIでPubMedを検索

PubMedの提供する医学論文データベースを日本語で検索できます。AI(Deep Learning)を活用した機械翻訳エンジンにより、精度高く日本語へ翻訳された論文をご参照いただけます。

みんなが読んでいる論文

ヒストンH3.3のリジン4は、胚性幹細胞の分化、制御領域でのヒストン濃縮、転写精度に必要とされています

Lysine 4 of histone H3.3 is required for embryonic stem cell differentiation, histone enrichment at regulatory regions and transcription accuracy.
  • Maja Gehre
  • Daria Bunina
  • Simone Sidoli
  • Marlena J Lübke
  • Nichole Diaz
  • Matteo Trovato
  • Benjamin A Garcia
  • Judith B Zaugg
  • Kyung-Min Noh
  • Nat. Genet..2020 03;52(3):273-282. 10.1038/s41588-020-0586-5. doi: 10.1038/s41588-020-0586-5.Epub 2020-03-05.

木材保存地における銅の植物抽出用タバコの銅抵抗性ソーマクロナール変異体1種とクローン2種の現地評価

Field evaluation of one Cu-resistant somaclonal variant and two clones of tobacco for copper phytoextraction at a wood preservation site.
  • Aliaksandr Kolbas
  • Rolf Herzig
  • Lilian Marchand
  • Jean-Paul Maalouf
  • Natallia Kolbas
  • Michel Mench
  • Environ Sci Pollut Res Int.2020 Aug;27(22):27831-27848. 10.1007/s11356-020-09151-y. doi: 10.1007/s11356-020-09151-y.Epub 2020-05-12.

2013年から2016年の間に米国食品医薬品局(FDA)が承認した薬剤との臨床的に関連する薬物動態に基づく薬物-薬物相互作用のリスク

Risk of Clinically Relevant Pharmacokinetic-Based Drug-Drug Interactions with Drugs Approved by the U.S. Food and Drug Administration Between 2013 and 2016.
  • Jingjing Yu
  • Zhu Zhou
  • Jessica Tay-Sontheimer
  • René H Levy
  • Isabelle Ragueneau-Majlessi
  • Drug Metab. Dispos..2018 Jun;46(6):835-845. dmd.117.078691. doi: 10.1124/dmd.117.078691.Epub 2018-03-23.

アゾール耐性カンジダ株に対して活性な大環状アミジノウレアであるBM1のin vitro特性評価、ADME解析、組織学的・毒性評価を行った

In vitro characterization, ADME analysis, and histological and toxicological evaluation of BM1, a macrocyclic amidinourea active against azole-resistant Candida strains.
  • Francesco Orofino
  • Giuseppina I Truglio
  • Diego Fiorucci
  • Ilaria D'Agostino
  • Matteo Borgini
  • Federica Poggialini
  • Claudio Zamperini
  • Elena Dreassi
  • Laura Maccari
  • Riccardo Torelli
  • Cecilia Martini
  • Micaela Bernabei
  • Jacques F Meis
  • Nitesh Kumar Khandelwal
  • Rajendra Prasad
  • Maurizio Sanguinetti
  • Francesca Bugli
  • Maurizio Botta
  • Int. J. Antimicrob. Agents.2020 Mar;55(3):105865. S0924-8579(19)30336-X. doi: 10.1016/j.ijantimicag.2019.105865.Epub 2019-12-20.

CDC14BとCDK1のUSP9Xに対するアンタゴニスティックな活性はWT1依存性の有糸分裂の転写と生存を制御する

Antagonistic activities of CDC14B and CDK1 on USP9X regulate WT1-dependent mitotic transcription and survival.
  • Michael Dietachmayr
  • Abirami Rathakrishnan
  • Oleksandra Karpiuk
  • Felix von Zweydorf
  • Thomas Engleitner
  • Vanesa Fernández-Sáiz
  • Petra Schenk
  • Marius Ueffing
  • Roland Rad
  • Martin Eilers
  • Christian Johannes Gloeckner
  • Katharina Clemm von Hohenberg
  • Florian Bassermann
  • Nat Commun.2020 03;11(1):1268. 10.1038/s41467-020-15059-5. doi: 10.1038/s41467-020-15059-5.Epub 2020-03-09.

フロリダ州ジャクソンビルのスーパーファンド灰サイトにおけるコミュニティベースの参加型調査。毒物学のトレーニングを実施して一般市民の知識を向上させた

Community-Based Participatory Research at Jacksonville Florida Superfund Ash Site: Toxicology Training to Improve the Knowledge of the Lay Community.
  • Alan Becker
  • Sandra Suther
  • Cynthia Harris
  • Grazyna Pawlowicz
  • Gale Tucker
  • Matthew Dutton
  • Fran Close
  • Aaron Hilliard
  • Richard Gragg
  • Fla Public Health Rev.2019 May;15(1-7):61-74.

COVID-19危機時の完全な人工呼吸サポートへの可能性のある橋渡しとしての流量制御弁を用いた差動換気。ベンチからベッドサイドへ

Differential Ventilation Using Flow Control Valves as a Potential Bridge to Full Ventilatory Support during the COVID-19 Crisis: From Bench to Bedside.
  • Matthew A Levin
  • Anjan Shah
  • Ronak Shah
  • Erica Kane
  • George Zhou
  • James B Eisenkraft
  • Martin D Chen
  • Daniel Katz
  • Chang Park
  • Cheuk Yin Lai
  • Garrett Burnett
  • Christopher Gidicsin
  • Jonathan Madek
  • Suzan Uysal
  • Roopa Kohli-Seth
  • Andrew B Leibowitz
  • Anesthesiology.2020 Jul;doi: 10.1097/ALN.0000000000003473.Epub 2020-07-02.

フッ化物の毒性:疫学研究、動物実験およびin vitro分析におけるヒト発達神経毒性の証拠の批判的評価

Toxicity of fluoride: critical evaluation of evidence for human developmental neurotoxicity in epidemiological studies, animal experiments and in vitro analyses.
  • Sabine Guth
  • Stephanie Hüser
  • Angelika Roth
  • Gisela Degen
  • Patrick Diel
  • Karolina Edlund
  • Gerhard Eisenbrand
  • Karl-Heinz Engel
  • Bernd Epe
  • Tilman Grune
  • Volker Heinz
  • Thomas Henle
  • Hans-Ulrich Humpf
  • Henry Jäger
  • Hans-Georg Joost
  • Sabine E Kulling
  • Alfonso Lampen
  • Angela Mally
  • Rosemarie Marchan
  • Doris Marko
  • Eva Mühle
  • Michael A Nitsche
  • Elke Röhrdanz
  • Richard Stadler
  • Christoph van Thriel
  • Stefan Vieths
  • Rudi F Vogel
  • Edmund Wascher
  • Carsten Watzl
  • Ute Nöthlings
  • Jan G Hengstler
  • Arch. Toxicol..2020 05;94(5):1375-1415. 10.1007/s00204-020-02725-2. doi: 10.1007/s00204-020-02725-2.Epub 2020-05-08.

熱走査アッセイを用いた多タンパク質原核生物のオルガネラへのプローブにより、コアとシェルの異なる特性が明らかになった

Probe into a multi-protein prokaryotic organelle using thermal scanning assay reveals distinct properties of the core and the shell.
  • Naimat K Bari
  • Jagadish P Hazra
  • Gaurav Kumar
  • Simerpreet Kaur
  • Sharmistha Sinha
  • Biochim Biophys Acta Gen Subj.2020 Jul;1864(10):129680. S0304-4165(20)30192-6. doi: 10.1016/j.bbagen.2020.129680.Epub 2020-07-04.

右側転移性大腸直腸癌に対するFOLFOXIRIと二重レジメンの比較。その後の治療法と全生存率への影響に焦点を当てる

FOLFOXIRI Versus Doublet Regimens in Right-Sided Metastatic Colorectal Cancer: Focus on Subsequent Therapies and Impact on Overall Survival.
  • Alexandre A Jácome
  • Bryan Kee
  • David Fogelman
  • Arvind Dasari
  • Imad Shureiqi
  • Kanwal Raghav
  • Van Morris
  • Benny Johnson
  • Michael Overman
  • Robert Wolff
  • Scott Kopetz
  • Jane Rogers
  • Shahab U Ahmed
  • Amir Mehdizadeh
  • Nicole Rothschild
  • Cathy Eng
  • Clin Colorectal Cancer.2020 Jun;S1533-0028(20)30083-9. doi: 10.1016/j.clcc.2020.05.010.Epub 2020-06-05.

褐色マダニRhipicephalus sanguineus (s.l.)のサイアロトランスクリプトームとサイアロプロテオームの統合的解析。血液摂食時の遺伝子発現の解明

Integrated analysis of sialotranscriptome and sialoproteome of the brown dog tick Rhipicephalus sanguineus (s.l.): Insights into gene expression during blood feeding.
  • Lucas Tirloni
  • Stephen Lu
  • Eric Calvo
  • Gabriela Sabadin
  • Lucia Sanchez Di Maggio
  • Motoshi Suzuki
  • Glenn Nardone
  • Itabajara da Silva Vaz
  • José M C Ribeiro
  • J Proteomics.2020 Jul;:103899. S1874-3919(20)30267-0. doi: 10.1016/j.jprot.2020.103899.Epub 2020-07-13.

ニューヨーク市におけるCOVID-19を持つ重症児と青年の臨床症状と転帰

Clinical Manifestations and Outcomes of Critically Ill Children and Adolescents with COVID-19 in New York City.
  • Kim R Derespina
  • Shubhi Kaushik
  • Anna Plichta
  • Edward E Conway
  • Asher Bercow
  • Jaeun Choi
  • Ruth Eisenberg
  • Jennifer Gillen
  • Anita I Sen
  • Claire M Hennigan
  • Lillian M Zerihun
  • Sule Doymaz
  • Michael A Keenaghan
  • Stephanie Jarrin
  • Franscene Oulds
  • Manoj Gupta
  • Louisdon Pierre
  • Melissa Grageda
  • H Michael Ushay
  • Vinay M Nadkarni
  • Michael S D Agus
  • Shivanand S Medar
  • J. Pediatr..2020 Jul;S0022-3476(20)30888-X. doi: 10.1016/j.jpeds.2020.07.039.Epub 2020-07-15.

三重陰性乳癌における長鎖遺伝子間ノンコーディングRNA 299遺伝子のDNAメチル化:前向き研究からの結果

DNA methylation of the long intergenic noncoding RNA 299 gene in triple-negative breast cancer: results from a prospective study.
  • Mehdi Manoochehri
  • Michael Jones
  • Katarzyna Tomczyk
  • Olivia Fletcher
  • Minouk J Schoemaker
  • Anthony J Swerdlow
  • Nasim Borhani
  • Ute Hamann
  • Sci Rep.2020 Jul;10(1):11762. 10.1038/s41598-020-68506-0. doi: 10.1038/s41598-020-68506-0.Epub 2020-07-16.

レスベラトロールの治療は、脂質制御と高脂肪食を与えられたウサギのリポタンパク質関連ホスホリパーゼA2(Lp-PLA2)の阻害に関連付けられています

Resveratrol Treatment Is Associated with Lipid Regulation and Inhibition of Lipoprotein-Associated Phospholipase A2 (Lp-PLA2) in Rabbits Fed a High-Fat Diet.
  • Lei Xu
  • Renjie Wang
  • Hongyu Liu
  • Jiaoqi Wang
  • Jing Mang
  • Zhongxin Xu
  • Evid Based Complement Alternat Med.2020;2020:9641582. doi: 10.1155/2020/9641582.Epub 2020-05-20.

間葉系間葉系間質細胞におけるDNA損傷修復応答:細胞の老化・老化からアポトーシス・分化能まで

DNA damage repair response in mesenchymal stromal cells: from cellular senescence and aging to apoptosis and differentiation ability.
  • Behnaz Banimohamad-Shotorbani
  • Houman Kahroba
  • Hadi Sadeghzadeh
  • David M Wilson
  • Hamid Maadi
  • Nasser Samadi
  • Mohammad Saeid Hejazi
  • Hekmat Farajpour
  • Behzad Nemati Onari
  • Mohammad Reza Sadeghi
  • Ageing Res. Rev..2020 Jul;:101125. S1568-1637(20)30260-9. doi: 10.1016/j.arr.2020.101125.Epub 2020-07-16.

シャルコー・マリー・トゥース神経症における軸索輸送障害とGlyRS-HDAC6相互作用の関連性

Aberrant GlyRS-HDAC6 interaction linked to axonal transport deficits in Charcot-Marie-Tooth neuropathy.
  • Zhongying Mo
  • Xiaobei Zhao
  • Huaqing Liu
  • Qinghua Hu
  • Xu-Qiao Chen
  • Jessica Pham
  • Na Wei
  • Ze Liu
  • Jiadong Zhou
  • Robert W Burgess
  • Samuel L Pfaff
  • C Thomas Caskey
  • Chengbiao Wu
  • Ge Bai
  • Xiang-Lei Yang
  • Nat Commun.2018 03;9(1):1007. 10.1038/s41467-018-03461-z. doi: 10.1038/s41467-018-03461-z.Epub 2018-03-08.

海洋生物侵入を評価するためのオンラインアンケートの利用。地中海沿岸3カ国でのレクリエーション漁業者と大西洋アブラガニCallinectes sapidus (Rathbun, 1986)を対象とした実証実験

Using online questionnaires to assess marine bio-invasions: A demonstration with recreational fishers and the Atlantic blue crab Callinectes sapidus (Rathbun, 1986) along three Mediterranean countries.
  • Jacopo Cerri
  • Stefania Chiesa
  • Luca Bolognini
  • Giorgio Mancinelli
  • Fabio Grati
  • Branko Dragičević
  • Jakov Dulčic
  • Ernesto Azzurro
  • Mar. Pollut. Bull..2020 Jul;156:111209. S0025-326X(20)30327-1. doi: 10.1016/j.marpolbul.2020.111209.Epub 2020-05-11.

ハイブリッドライ麦のバイオマス収量予測を改善するために、遺伝子型、ハイパースペクトル、表現型データを統合する

Integration of genotypic, hyperspectral, and phenotypic data to improve biomass yield prediction in hybrid rye.
  • Rodrigo José Galán
  • Angela-Maria Bernal-Vasquez
  • Christian Jebsen
  • Hans-Peter Piepho
  • Patrick Thorwarth
  • Philipp Steffan
  • Andres Gordillo
  • Thomas Miedaner
  • Theor. Appl. Genet..2020 Jul;10.1007/s00122-020-03651-8. doi: 10.1007/s00122-020-03651-8.Epub 2020-07-17.

大腿骨セグメント欠損に対するMasquelet手技の第II期における髄腔内爪と人工関節への線維性支柱移植の追加。手技のヒント

Adding a Fibular Strut Allograft to Intramedullary Nail and Cancellous Autograft During Stage II of the Masquelet Technique for Segmental Femur Defects: A Technique Tip.
  • Omar Ramos
  • Michael Mariorenzi
  • Joey P Johnson
  • Roman A Hayda
  • J Am Acad Orthop Surg Glob Res Rev.2020 Jul;4(7):e1900179. 01979360-202007000-00006. doi: 10.5435/JAAOSGlobal-D-19-00179.

インドネシアの土壌菌、Talaromyces pinophilusに由来するPlasmodium falciparum dihydroorotate dehydrogenaseに対して活性な微生物阻害剤 BioMCC-f.T.3979

Microbial inhibitors active against Plasmodium falciparum dihydroorotate dehydrogenase derived from an Indonesian soil fungus, Talaromyces pinophilus BioMCC-f.T.3979.
  • Amila Pramisandi
  • Kazuyuki Dobashi
  • Mihoko Mori
  • Kenichi Nonaka
  • Atsuko Matsumoto
  • Toshiyuki Tokiwa
  • Mayuka Higo
  • Kristiningrum
  • Eri Amalia
  • Arif Nurkanto
  • Daniel Ken Inaoka
  • Danang Waluyo
  • Kiyoshi Kita
  • Tomoyoshi Nozaki
  • Satoshi Ōmura
  • Kazuro Shiomi
  • J. Gen. Appl. Microbiol..2020 Jul;doi: 10.2323/jgam.2019.11.007.Epub 2020-07-14.

ヒトフィブロネクチンのエキストラドメインAとHPV16/18 E7ウイルス抗原との融合タンパク質からなるHPV16/18遺伝子型に対する二価ワクチンの開発

Bivalent therapeutic vaccine against HPV16/18 genotypes consisting of a fusion protein between the extra domain A from human fibronectin and HPV16/18 E7 viral antigens.
  • Laura Arribillaga
  • Iciar Echeverria
  • Viriginia Belsue
  • Timothy Gomez
  • Teresa Lozano
  • Noelia Casares
  • Lorea Villanueva
  • Sonia Domingos-Pereira
  • Pedro J Romero
  • Denise Nardelli-Haefliger
  • Sandra Hervás-Stubbs
  • Pablo Sarobe
  • María Josefa Rodriguez
  • José L Carrascosa
  • Thomas Zürcher
  • Juan José Lasarte
  • J Immunother Cancer.2020 06;8(1). e000704. doi: 10.1136/jitc-2020-000704.

放射線は、RAW 264.7細胞およびマウス骨髄由来マクロファージの細胞骨格および溶解酵素を制御することにより、破骨細胞形成を変化させる

Radiation alters osteoclastogenesis by regulating the cytoskeleton and lytic enzymes in RAW 264.7 cells and mouse bone marrow-derived macrophages.
  • Ling Tong
  • Yuyang Wang
  • Jianping Wang
  • Feilong He
  • Jianglong Zhai
  • Jiangtao Bai
  • Guoying Zhu
  • Int. J. Radiat. Biol..2020 Jul;:1-26. doi: 10.1080/09553002.2020.1798542.Epub 2020-07-20.

空間的に構造化された集団における感染症の発生規模は、局所的な伝播と長距離分散のトレードオフが駆動している

Trade-off between local transmission and long-range dispersal drives infectious disease outbreak size in spatially structured populations.
  • Elisa Benincà
  • Thomas Hagenaars
  • Gert Jan Boender
  • Jan van de Kassteele
  • Michiel van Boven
  • PLoS Comput. Biol..2020 Jul;16(7):e1008009. PCOMPBIOL-D-19-01465. doi: 10.1371/journal.pcbi.1008009.Epub 2020-07-06.

分数的要因設計と中央複合設計の組み合わせを用いた、魚類副産物からのうま味成分の超音波支援酵素抽出条件の最適化

Optimisation of ultrasound-assisted enzymatic extraction conditions of umami compounds from fish by-products using the combination of fractional factorial design and central composite design.
  • Fabrice Bruno Siewe
  • Tanaji G Kudre
  • Bhaskar Narayan
  • Food Chem.2020 Jul;334:127498. S0308-8146(20)31360-1. doi: 10.1016/j.foodchem.2020.127498.Epub 2020-07-10.

化学感覚細胞由来のアセチルコリンは気管粘膜クリアランスをウイルス性ホルミルペプチドに応答して駆動する

Chemosensory Cell-Derived Acetylcholine Drives Tracheal Mucociliary Clearance in Response to Virulence-Associated Formyl Peptides.
  • Alexander Perniss
  • Shuya Liu
  • Brett Boonen
  • Maryam Keshavarz
  • Anna-Lena Ruppert
  • Thomas Timm
  • Uwe Pfeil
  • Aichurek Soultanova
  • Soumya Kusumakshi
  • Lucas Delventhal
  • Öznur Aydin
  • Martina Pyrski
  • Klaus Deckmann
  • Torsten Hain
  • Nadine Schmidt
  • Christa Ewers
  • Andreas Günther
  • Günter Lochnit
  • Vladimir Chubanov
  • Thomas Gudermann
  • Johannes Oberwinkler
  • Jochen Klein
  • Katsuhiko Mikoshiba
  • Trese Leinders-Zufall
  • Stefan Offermanns
  • Burkhard Schütz
  • Ulrich Boehm
  • Frank Zufall
  • Bernd Bufe
  • Wolfgang Kummer
  • Immunity.2020 Apr;52(4):683-699.e11. S1074-7613(20)30118-7. doi: 10.1016/j.immuni.2020.03.005.