あなたは歯科・医療関係者ですか？

WHITE CROSSは、歯科・医療現場で働く方を対象に、良質な歯科医療情報の提供を目的とした会員制サイトです。

日本語AIでPubMedを検索

歯科医師情報サイトTOP / PubMed論文検索

日本語AIでPubMedを検索

PubMedの提供する医学論文データベースを日本語で検索できます。AI(Deep Learning)を活用した機械翻訳エンジンにより、精度高く日本語へ翻訳された論文をご参照いただけます。
対象期間    ～ 

みんなが読んでいる論文

肝脾腫、肺炎、骨変化、前頭側頭型認知症。ニーマンピックB型とSQSTM1-related Paget's diseaseの同一個体での発症

Hepatosplenomegaly, pneumopathy, bone changes and fronto-temporal dementia: Niemann-Pick type B and SQSTM1-associated Paget's disease in the same individual.
  • Camelia Voinea
  • Elena Gonzalez Rodriguez
  • Catherine Beigelman-Aubry
  • Victor Leroy
  • Bérengère Aubry-Rozier
  • Belinda Campos-Xavier
  • Diana Ballhausen
  • Romain Lazor
  • Frédéric Barbey
  • Luisa Bonafé
  • Andrea Superti-Furga
  • Christel Tran
  • J. Bone Miner. Metab..2019 Mar;37(2):378-383. 10.1007/s00774-018-0932-1. doi: 10.1007/s00774-018-0932-1.Epub 2018-06-14.

シストソーマ由来のフルクトース-1,6-ビスフォスフェートアルドラーゼとシスタチンによる1型糖尿病の改善に関する研究

Amelioration of type 1 diabetes by recombinant fructose-1,6-bisphosphate aldolase and cystatin derived from Schistosoma japonicum in a murine model.
  • Ke Yan
  • Bo Wang
  • Huabang Zhou
  • Qingli Luo
  • Jilong Shen
  • Yunxia Xu
  • Zhengrong Zhong
  • Parasitol. Res..2020 Jan;119(1):203-214. 10.1007/s00436-019-06511-7. doi: 10.1007/s00436-019-06511-7.Epub 2019-12-16.

エクイヌ脂肪間葉系幹細胞におけるCRISPR/Cas9技術によるプロスタグランジンE2受容体EP2およびEP4のエディション

Edition of Prostaglandin E2 Receptors EP2 and EP4 by CRISPR/Cas9 Technology in Equine Adipose Mesenchymal Stem Cells.
  • Ana Carolina Furlanetto Mançanares
  • Joel Cabezas
  • José Manríquez
  • Vanessa Cristina de Oliveira
  • Yat Sen Wong Alvaro
  • Daniela Rojas
  • Felipe Navarrete Aguirre
  • Lleretny Rodriguez-Alvarez
  • Fidel Ovidio Castro
  • Animals (Basel).2020 Jun;10(6). E1078. doi: 10.3390/ani10061078.Epub 2020-06-23.

遺伝的リスクと母親の子育てと精神病理と子供のADHDの症状と攻撃性の背景にある縦断的な伝達過程の役割を検討しています。プロスペクティブ養子縁組デザインの利点を利用して

Examining the Role of Genetic Risk and Longitudinal Transmission Processes Underlying Maternal Parenting and Psychopathology and Children's ADHD Symptoms and Aggression: Utilizing the Advantages of a Prospective Adoption Design.
  • Ruth Sellers
  • Gordon T Harold
  • Anita Thapar
  • Jenae M Neiderhiser
  • Jody M Ganiban
  • David Reiss
  • Daniel S Shaw
  • Misaki N Natsuaki
  • Leslie D Leve
  • Behav. Genet..2020 Jul;50(4):247-262. 10.1007/s10519-020-10006-y. doi: 10.1007/s10519-020-10006-y.Epub 2020-07-04.

(S)-(-)-リモネンの局所適用は，ラットの損傷した骨格筋の酸化パラメータを改善するためにフォノフォレーシスと同様に有効である．

Topical application of (S)-(-)-limonene is as effective as phonophoresis for improving oxidative parameters of injured skeletal muscle in rats.
  • Marta Maria Barbosa Santos
  • Luís Fernando Sousa Filho
  • Jéssica Batista De Souza
  • José Evaldo Rodrigues De Menezes Filho
  • Thássio Ricardo Ribeiro Mesquita
  • Michel Santana Santos
  • Carla Maria Lins De Vasconcelos
  • Sandra Lauton-Santos
  • Evaleide Diniz De Oliveira
  • Naunyn Schmiedebergs Arch. Pharmacol..2020 Jul;10.1007/s00210-020-01941-y. doi: 10.1007/s00210-020-01941-y.Epub 2020-07-11.

分光光度法による解離力向上のための相対吸光度分布の概念。純度指数と均一性評価のためのツール

The concept of Relative Absorptivity Distribution for enhancing disbanding power of spectrophotometric technique to resolve co-formulated tablets: A tool for purity index and uniformity assessment.
  • Hayam M Lotfy
  • Mona S Elshahed
  • Dalia Mohamed
  • Spectrochim Acta A Mol Biomol Spectrosc.2020 Oct;239:118551. S1386-1425(20)30530-8. doi: 10.1016/j.saa.2020.118551.Epub 2020-05-29.

KORARCデータベース（730例の多施設ロボット根治的膀胱摘出術データベース）を用いた膀胱癌患者におけるロボット支援根治的膀胱摘出術後のpentafecta達成度に応じた腫瘍学的転帰

Oncological outcome according to attainment of pentafecta after robot assisted radical cystectomy among bladder cancer patients using KORARC database (730 multicenter robot radical cystectomy database).
  • Jong Jin Oh
  • Sangchul Lee
  • Ja Hyeon Ku
  • Tae Gyun Kwon
  • Tae-Hwan Kim
  • Seung Hyun Jeon
  • Sang Hyup Lee
  • Jong Kil Nam
  • Wan Seok Kim
  • Byong Chang Jeong
  • Ji Youl Lee
  • Sung Hoo Hong
  • Koon Ho Rha
  • Woong Kyu Han
  • Won Sik Ham
  • Young Goo Lee
  • Yong Seong Lee
  • Sung Yul Park
  • Young Eun Yoon
  • Sung Gu Kang
  • Seok Ho Kang
  • BJU Int..2020 Jul;doi: 10.1111/bju.15178.Epub 2020-07-18.

アカミミズクモ（Trachemys scripta elegans）とカエデカメ（Graptemys spp.）における甲状腺ホルモン値と血漿毛細帯電気泳動の季節と性別による比較

A comparison of thyroid hormone levels and plasma capillary zone electrophoresis in red-eared sliders (Trachemys scripta elegans) and map turtles (Graptemys spp.) depending on season and sex.
  • Christoph Leineweber
  • Sabine Öfner
  • Anke C Stöhr
  • Rachel E Marschang
  • Karina Mathes
  • Vet Clin Pathol.2020 Mar;49(1):78-90. doi: 10.1111/vcp.12838.Epub 2020-04-01.

植込み型除細動器を提供された患者に対するDECIDE-ICDの共有化されたDECISION SUPPORT Interventionの多施設共同試験。DECIDE-ICDの根拠、デザイン、メディケアの変更、パイロットデータ

A multicenter trial of a shared DECision Support Intervention for Patients offered implantable Cardioverter-DEfibrillators: DECIDE-ICD rationale, design, Medicare changes, and pilot data.
  • Bryan C Wallace
  • Larry A Allen
  • Christopher E Knoepke
  • Russell E Glasgow
  • Carmen L Lewis
  • Diane L Fairclough
  • Laura J Helmkamp
  • Monica D Fitzgerald
  • Wendy S Tzou
  • Daniel B Kramer
  • Paul D Varosy
  • Sanjaya K Gupta
  • John M Mandrola
  • Scott C Brancato
  • Pamela N Peterson
  • Daniel D Matlock
  • Am. Heart J..2020 Apr;226:161-173. S0002-8703(20)30116-2. doi: 10.1016/j.ahj.2020.04.010.Epub 2020-04-20.

新生児集中治療室に入院した早産児の入院期間の予測因子。院内での入院期間を予測するためには、入院期間を短縮することが重要である

Predictors of length of hospital stay among preterm infants admitted to neonatal intensive care unit: Data from a multicentre collaborative network from India (INNC: Indian National Neonatal Collaborative).
  • Srinivas Murki
  • Venkateshwarlu Vardhelli
  • Saikiran Deshabhotla
  • Deepak Sharma
  • Dinesh Pawale
  • Dattatray Kulkarni
  • Praveen Kumar
  • Nandkishor S Kabra
  • Mangalabharathi Sundaram
  • Nishad Plakkal
  • Ashish Mehta
  • Baswaraj Tandur
  • Deepak Chawla
  • Subramanian Sreeram
  • Bijan Saha
  • P N Suman Rao
  • Sandeep Kadam
  • J Paediatr Child Health.2020 Jul;doi: 10.1111/jpc.15031.Epub 2020-07-13.

エチオピア北西部Debre Tabor町の生殖年齢女性のパートナーにおけるヒト免疫ウイルスの母子感染防止への男性の関与と関連因子：コミュニティに基づく横断的研究

Male involvement in prevention of mother to child transmission of human immuno virus and associated factors among partners' of reproductive age women at Debre Tabor town, Northwest Ethiopia: a community based cross sectional study.
  • Enyew Dagnew
  • Miteku Andualem
  • Temesegen Worku
  • Dawit Gebeyehu
  • Wubet Taklual
  • Abenezer Melkie
  • BMC Res Notes.2020 Mar;13(1):190. 10.1186/s13104-020-05023-3. doi: 10.1186/s13104-020-05023-3.Epub 2020-03-30.

大動脈経カテーテル大動脈弁留置術を受けた患者に対する意識的鎮静のみと比較した併用催眠療法の周術期成績

Perioperative Outcomes of Adjunctive Hypnotherapy Compared with Conscious Sedation Alone for Patients Undergoing Transfemoral Transcatheter Aortic Valve Implantation.
  • Masao Takahashi
  • Gauthier Mouillet
  • Asmaa Khaled
  • Madjid Boukantar
  • Romain Gallet
  • Vladimir Rubimbura
  • Pascal Lim
  • Jean-Luc Dubois-Rande
  • Emmanuel Teiger
  • Int Heart J.2020 Jan;61(1):60-66. doi: 10.1536/ihj.19-296.Epub 2020-01-17.

視床下部発生の分子設計

Molecular design of hypothalamus development.
  • Roman A Romanov
  • Evgenii O Tretiakov
  • Maria Eleni Kastriti
  • Maja Zupancic
  • Martin Häring
  • Solomiia Korchynska
  • Konstantin Popadin
  • Marco Benevento
  • Patrick Rebernik
  • Francois Lallemend
  • Katsuhiko Nishimori
  • Frédéric Clotman
  • William D Andrews
  • John G Parnavelas
  • Matthias Farlik
  • Christoph Bock
  • Igor Adameyko
  • Tomas Hökfelt
  • Erik Keimpema
  • Tibor Harkany
  • Nature.2020 06;582(7811):246-252. 10.1038/s41586-020-2266-0. doi: 10.1038/s41586-020-2266-0.Epub 2020-05-06.

欧州における健康研究の分断化の克服：COVID-19からの教訓

Overcoming fragmentation of health research in Europe: lessons from COVID-19.
  • Karin R Sipido
  • Fernando Antoñanzas
  • Julio Celis
  • Laurent Degos
  • Richard Frackowiak
  • Valentin Fuster
  • Detlev Ganten
  • Steffen Gay
  • Hans Hofstraat
  • Stephen T Holgate
  • Gabriel Krestin
  • Michael Manns
  • Francoise Meunier
  • Wolfgang Oertel
  • Susanna Palkonen
  • Dainius Pavalkis
  • Helga Rübsamen-Schaeff
  • Ulf Smith
  • Bente Merete Stallknecht
  • Tomáš Zima
  • Lancet.2020 06;395(10242):1970-1971. S0140-6736(20)31411-2. doi: 10.1016/S0140-6736(20)31411-2.Epub 2020-06-16.

ミリ秒 H/D 交換質量分析を使用した血管内皮成長因子 A の拡張コンストラクト上での臨床前の Bevacizumab (Avastin) バイオシミラーのエピトープ マッピング

Epitope Mapping for a Pre-Clinical Bevacizumab (Avastin) Biosimilar on an Extended Construct of Vascular Endothelial Growth Factor-A using Millisecond H/D Exchange Mass Spectrometry.
  • Kerene A Brown
  • Cristina Lento
  • Shanthi Rajendran
  • Jason Dowd
  • Derek J Wilson
  • Biochemistry.2020 Jul;doi: 10.1021/acs.biochem.0c00308.Epub 2020-07-16.

ノースカロライナ州におけるMPID-NGSによる最近のHIV感染、薬剤耐性変異、および感染ネットワークのほぼリアルタイム同定

Near Real-Time Identification of Recent HIV Transmissions, Transmitted Drug Resistance Mutations, and Transmission Networks by MPID-NGS in North Carolina.
  • Shuntai Zhou
  • Sabrina Sizemore
  • Matt Moeser
  • Scott Zimmerman
  • Erika Samoff
  • Victoria Mobley
  • Simon Frost
  • Andy Cressman
  • Michael Clark
  • Tara Skelly
  • Hemant Kelkar
  • Umadevi Veluvolu
  • Corbin Jones
  • Joseph Eron
  • Myron Cohen
  • Julie A E Nelson
  • Ronald Swanstrom
  • Ann M Dennis
  • J. Infect. Dis..2020 Jul;jiaa417. doi: 10.1093/infdis/jiaa417.Epub 2020-07-14.

Plasmodium vivax Merozoite Surface Protein 3αに対する相補固定抗体の誘導と動態、免疫グロブリンGサブクラスおよび免疫グロブリンMとの関係について

Induction and Kinetics of Complement-Fixing Antibodies Against Plasmodium vivax Merozoite Surface Protein 3α and Relationship With Immunoglobulin G Subclasses and Immunoglobulin M.
  • Damian A Oyong
  • Danny W Wilson
  • Bridget E Barber
  • Timothy William
  • Jianlin Jiang
  • Mary R Galinski
  • Freya J I Fowkes
  • Matthew J Grigg
  • James G Beeson
  • Nicholas M Anstey
  • Michelle J Boyle
  • J. Infect. Dis..2019 11;220(12):1950-1961. 5550848. doi: 10.1093/infdis/jiz407.

ミノサイクリンとメチルプレドニゾロンの併用治療が実験的脊髄損傷における腫瘍壊死因子αとインターロイキン-6の発現に及ぼす影響：光と電子顕微鏡による研究

Effects of combined treatment of minocycline and methylprednisolone on the expression of tumor necrosis factor alpha and interleukine-6 in experimental spinal cord injury: a light and electron microscopic study.
  • Leman Sencar
  • Derviş Mansuri Yilmaz
  • Abdullah Tuli
  • Sait Polat
  • Ultrastruct Pathol.2020 Jun;:1-17. doi: 10.1080/01913123.2020.1771493.Epub 2020-06-22.

羽毛型TCF7L2はニコチン中毒と糖尿病を結びつける

Habenular TCF7L2 links nicotine addiction to diabetes.
  • Alexander Duncan
  • Mary P Heyer
  • Masago Ishikawa
  • Stephanie P B Caligiuri
  • Xin-An Liu
  • Zuxin Chen
  • Maria Vittoria Micioni Di Bonaventura
  • Karim S Elayouby
  • Jessica L Ables
  • William M Howe
  • Purva Bali
  • Clementine Fillinger
  • Maya Williams
  • Richard M O'Connor
  • Zichen Wang
  • Qun Lu
  • Theodore M Kamenecka
  • Avi Ma'ayan
  • Heidi C O'Neill
  • Ines Ibanez-Tallon
  • Aron M Geurts
  • Paul J Kenny
  • Nature.2019 10;574(7778):372-377. 10.1038/s41586-019-1653-x. doi: 10.1038/s41586-019-1653-x.Epub 2019-10-16.

チチンのC末端PEVKエクソンを削除すると、受動的な筋剛性が増加し、スプライシングが変化し、骨格筋の断面および縦方向の肥大が誘導されることが明らかになった

Deleting Titin's C-Terminal PEVK Exons Increases Passive Stiffness, Alters Splicing, and Induces Cross-Sectional and Longitudinal Hypertrophy in Skeletal Muscle.
  • Robbert J van der Pijl
  • Brian Hudson
  • Tomotaroh Granzier-Nakajima
  • Frank Li
  • Anne M Knottnerus
  • John Smith
  • Charles S Chung
  • Michael Gotthardt
  • Henk L Granzier
  • Coen A C Ottenheijm
  • Front Physiol.2020;11:494. doi: 10.3389/fphys.2020.00494.Epub 2020-05-29.

心筋β-アドレナリン受容体の活性化は、コンネキシン43の発現と分布における細胞タイプ依存性の異なる変化を媒介する

Cardiac β-adrenergic receptor activation mediates distinct and cell type-dependent changes in the expression and distribution of connexin 43.
  • Yi Zhang
  • Meng-Chen Hou
  • Jing-Jing Li
  • Ying Qi
  • Yu Zhang
  • Gang She
  • Yu-Jie Ren
  • Wei Wu
  • Zheng-Da Pang
  • Wenjun Xie
  • Xiu-Ling Deng
  • Xiao-Jun Du
  • J. Cell. Mol. Med..2020 Jun;doi: 10.1111/jcmm.15469.Epub 2020-06-24.

グリーンルーフの5年間の運用において、廃材をグリーンルーフ下地として再利用することで、グリーンルーフからの炭素排出を効果的に抑制できるかどうか？

Whether the carbon emission from green roofs can be effectively mitigated by recycling waste building material as green roof substrate during five-year operation?
  • Liangqian Fan
  • Jingting Wang
  • Xiaoling Liu
  • Hongbing Luo
  • Ke Zhang
  • Xiaoying Fu
  • Mei Li
  • Xiaoting Li
  • Bing Jiang
  • Jia Chen
  • Shuzhi Fu
  • You Mo
  • Lin Li
  • Wei Chen
  • Lin Cheng
  • Fenghui Chen
  • Lin Ji
  • Dandan Ma
  • Xiaohong Zhang
  • Bruce C Anderson
  • Environ Sci Pollut Res Int.2020 Jul;10.1007/s11356-020-09896-6. doi: 10.1007/s11356-020-09896-6.Epub 2020-07-17.

悪性尿路閉塞症治療における二重JカテーテルのAntegrade挿入：大学病院における修正術式で得られた結果のレトロスペクティブ解析

Antegrade insertion of a double J catheter in the treatment of malignant ureteral obstruction: a retrospective analysis of the results obtained with a modified technique at a university hospital.
  • Rômulo Florêncio Tristão Santos
  • Tiago Kojun Tibana
  • Edson Marchiori
  • Thiago Franchi Nunes
  • Radiol Bras.2020 May-Jun;53(3):155-160. doi: 10.1590/0100-3984.2019.0090.

BDNFの過剰発現は線条体神経細胞のD3受容体レベルを増加させ、D1受容体アゴニスト誘発性ジスキネジアを悪化させる

BDNF Overexpression Increases Striatal D3 Receptor Level at Striatal Neurons and Exacerbates D1-Receptor Agonist-Induced Dyskinesia.
  • Simona Scheggi
  • Francesca Rossi
  • Sara Corsi
  • Silvia Fanni
  • Elisabetta Tronci
  • Congiu Ludovica
  • Romina Vargiu
  • Carla Gambarana
  • Ana Muñoz
  • Roberto Stancampiano
  • Anders Bjorklund
  • Manolo Carta
  • J Parkinsons Dis.2020 Jul;JPD202061. doi: 10.3233/JPD-202061.Epub 2020-07-08.

ヒストン脱アセチル化酵素6/8とブロモドメインBRPF1のデュアルターゲティング阻害剤の設計、合成、生物学的評価

Design, synthesis, and biological evaluation of dual targeting inhibitors of histone deacetylase 6/8 and bromodomain BRPF1.
  • Ehab Ghazy
  • Patrik Zeyen
  • Daniel Herp
  • Martin Hügle
  • Karin Schmidtkunz
  • Frank Erdmann
  • Dina Robaa
  • Matthias Schmidt
  • Elizabeth R Morales
  • Christophe Romier
  • Stefan Günther
  • Manfred Jung
  • Wolfgang Sippl
  • Eur J Med Chem.2020 Aug;200:112338. S0223-5234(20)30307-X. doi: 10.1016/j.ejmech.2020.112338.Epub 2020-05-18.

Mthfd2はミトコンドリア機能とDNA修復を調節し、マウス幹細胞の多能性を維持する

Mthfd2 Modulates Mitochondrial Function and DNA Repair to Maintain the Pluripotency of Mouse Stem Cells.
  • Liang Yue
  • Yangli Pei
  • Liang Zhong
  • Henry Yang
  • Yanliang Wang
  • Wei Zhang
  • Naixin Chen
  • Qianqian Zhu
  • Jie Gao
  • Minglei Zhi
  • Bingqiang Wen
  • Shaopeng Zhang
  • Jinzhu Xiang
  • Qingqing Wei
  • Hui Liang
  • Suying Cao
  • Huiqiang Lou
  • Zhongzhou Chen
  • Jianyong Han
  • Stem Cell Reports.2020 Jul;S2213-6711(20)30239-3. doi: 10.1016/j.stemcr.2020.06.018.Epub 2020-07-02.

リンパ性新生物における全ゲノムシークエンシングから免疫グロブリン遺伝子再配列と発がん性転座を再構築するためのIgCaller

IgCaller for reconstructing immunoglobulin gene rearrangements and oncogenic translocations from whole-genome sequencing in lymphoid neoplasms.
  • Ferran Nadeu
  • Rut Mas-de-Les-Valls
  • Alba Navarro
  • Romina Royo
  • Silvia Martín
  • Neus Villamor
  • Helena Suárez-Cisneros
  • Rosó Mares
  • Junyan Lu
  • Anna Enjuanes
  • Alfredo Rivas-Delgado
  • Marta Aymerich
  • Tycho Baumann
  • Dolors Colomer
  • Julio Delgado
  • Ryan D Morin
  • Thorsten Zenz
  • Xose S Puente
  • Peter J Campbell
  • Sílvia Beà
  • Francesco Maura
  • Elías Campo
  • Nat Commun.2020 Jul;11(1):3390. 10.1038/s41467-020-17095-7. doi: 10.1038/s41467-020-17095-7.Epub 2020-07-07.

Corrigendum to "Partial least squares and linear support vector regression chemometric models for analysis of Norfloxacin and Tinidazole with Tinidazole impurity" Spectrochim.Acta A: Mol.Biomol.Spectrosc.239巻、2020年10月5日、118513

Corrigendum to "Partial least squares and linear support vector regression chemometric models for analysis of Norfloxacin and Tinidazole with Tinidazole impurity" [Spectrochim. Acta A: Mol. Biomol. Spectrosc. Volume 239, 5 October 2020, 118513].
  • Ibrahim A Naguib
  • Eglal A Abdelaleem
  • Eman S Hassan
  • Nouruddin W Ali
  • Mohammed Gamal
  • Spectrochim Acta A Mol Biomol Spectrosc.2020 Jul;241:118696. S1386-1425(20)30675-2. doi: 10.1016/j.saa.2020.118696.Epub 2020-07-13.

腎生検後の糸球体腎炎患者におけるがん発症と死亡率の差：単一施設レトロスペクティブコホート研究

Cancer development and mortality differences in patients with glomerulonephritis after renal biopsy: a single center retrospective cohort study.
  • Hyunjin Ryu
  • Kipyo Kim
  • Jiwon Ryu
  • Hyung-Eun Son
  • Ji-Young Ryu
  • Sejoong Kim
  • Ki Young Na
  • Dong Wan Chae
  • Ho Jun Chin
  • BMC Nephrol.2020 Jun;21(1):221. 10.1186/s12882-020-01882-x. doi: 10.1186/s12882-020-01882-x.Epub 2020-06-10.

クレードF AAVHSCは、非ヒト霊長類に静脈内投与した後、血液脳関門を通過し、末梢組織に加えて中枢神経系にも導入されます

Clade F AAVHSCs cross the blood brain barrier and transduce the central nervous system in addition to peripheral tissues following intravenous administration in nonhuman primates.
  • Jeff L Ellsworth
  • Jacinthe Gingras
  • Laura J Smith
  • Hillard Rubin
  • Tania A Seabrook
  • Kruti Patel
  • Nicole Zapata
  • Kevin Olivieri
  • Michael O'Callaghan
  • Elizabeth Chlipala
  • Pablo Morales
  • Albert Seymour
  • PLoS ONE.2019;14(11):e0225582. PONE-D-19-21158. doi: 10.1371/journal.pone.0225582.Epub 2019-11-26.

副産物の価値化に伴う課題-超音波処理した植物由来副産物と発酵させた植物由来副産物の安全性パラメータの比較研究

Challenges Associated with Byproducts Valorization-Comparison Study of Safety Parameters of Ultrasonicated and Fermented Plant-Based Byproducts.
  • Elena Bartkiene
  • Vadims Bartkevics
  • Iveta Pugajeva
  • Anastasija Borisova
  • Egle Zokaityte
  • Vita Lele
  • Vytaute Sakiene
  • Paulina Zavistanaviciute
  • Dovile Klupsaite
  • Daiva Zadeike
  • Fatih Özogul
  • Grazina Juodeikiene
  • Foods.2020 May;9(5). E614. doi: 10.3390/foods9050614.Epub 2020-05-11.

PCAREとWASF3は、光受容体外側セグメントディスク形成の開始に必要な毛様体F-アクチンアセンブリを制御しています

PCARE and WASF3 regulate ciliary F-actin assembly that is required for the initiation of photoreceptor outer segment disk formation.
  • Julio C Corral-Serrano
  • Ideke J C Lamers
  • Jeroen van Reeuwijk
  • Lonneke Duijkers
  • Anita D M Hoogendoorn
  • Adem Yildirim
  • Nikoleta Argyrou
  • Renate A A Ruigrok
  • Stef J F Letteboer
  • Rossano Butcher
  • Max D van Essen
  • Sanae Sakami
  • Sylvia E C van Beersum
  • Krzysztof Palczewski
  • Michael E Cheetham
  • Qin Liu
  • Karsten Boldt
  • Uwe Wolfrum
  • Marius Ueffing
  • Alejandro Garanto
  • Ronald Roepman
  • Rob W J Collin
  • Proc. Natl. Acad. Sci. U.S.A..2020 May;117(18):9922-9931. 1903125117. doi: 10.1073/pnas.1903125117.Epub 2020-04-20.

グリオブラストーマの骨髄由来サプレッサー細胞サブセットは、免疫抑制を低減するために標的化できるマクロファージ移行阻害因子受容体のプロファイルを異なる形で発現している

Glioblastoma Myeloid-Derived Suppressor Cell Subsets Express Differential Macrophage Migration Inhibitory Factor Receptor Profiles That Can Be Targeted to Reduce Immune Suppression.
  • Tyler J Alban
  • Defne Bayik
  • Balint Otvos
  • Anja Rabljenovic
  • Lin Leng
  • Leu Jia-Shiun
  • Gustavo Roversi
  • Adam Lauko
  • Arbaz A Momin
  • Alireza M Mohammadi
  • David M Peereboom
  • Manmeet S Ahluwalia
  • Kazuko Matsuda
  • Kyuson Yun
  • Richard Bucala
  • Michael A Vogelbaum
  • Justin D Lathia
  • Front Immunol.2020;11:1191. doi: 10.3389/fimmu.2020.01191.Epub 2020-06-18.

COVID-19 を有する成人入院患者における短期生存率を予測するためのリスク因子に基づくシステムの開発と検証：多施設，レトロスペクティブ，コホート研究

Development and validation of a risk factor-based system to predict short-term survival in adult hospitalized patients with COVID-19: a multicenter, retrospective, cohort study.
  • Shuai Zhang
  • Mengfei Guo
  • Limin Duan
  • Feng Wu
  • Guorong Hu
  • Zhihui Wang
  • Qi Huang
  • Tingting Liao
  • Juanjuan Xu
  • Yanling Ma
  • Zhilei Lv
  • Wenjing Xiao
  • Zilin Zhao
  • Xueyun Tan
  • Daquan Meng
  • Shujing Zhang
  • E Zhou
  • Zhengrong Yin
  • Wei Geng
  • Xuan Wang
  • Jianchu Zhang
  • Jianguo Chen
  • Yu Zhang
  • Yang Jin
  • Crit Care.2020 Jul;24(1):438. 10.1186/s13054-020-03123-x. doi: 10.1186/s13054-020-03123-x.Epub 2020-07-16.

加齢マウスにおけるセラミド発現の組織特異的スクリーニングにより、骨格筋の繊維サイズと強度の潜在的な調節因子としてセラミド合成酵素-1とセラミド合成酵素-5が同定された

A tissue-specific screen of ceramide expression in aged mice identifies ceramide synthase-1 and ceramide synthase-5 as potential regulators of fiber size and strength in skeletal muscle.
  • Bettina Tosetti
  • Susanne Brodesser
  • Anna Brunn
  • Martina Deckert
  • Matthias Blüher
  • Wolfram Doehner
  • Stefan D Anker
  • Daniela Wenzel
  • Bernd Fleischmann
  • Carola Pongratz
  • Franziska Peters
  • Olaf Utermöhlen
  • Martin Krönke
  • Aging Cell.2020 01;19(1):e13049. doi: 10.1111/acel.13049.Epub 2019-11-06.

一般的なピピストレルPipistrellleus pipistrellus (Chiroptera: Vespertilionidae)とコウモリ軟ダニArgas vespertilionis (Ixodida: Argasidae)におけるRickettsiae

Rickettsiae in the common pipistrelle Pipistrellus pipistrellus (Chiroptera: Vespertilionidae) and the bat soft tick Argas vespertilionis (Ixodida: Argasidae).
  • Shuo Zhao
  • Meihua Yang
  • Gang Liu
  • Sándor Hornok
  • Shanshan Zhao
  • Chunli Sang
  • Wenbo Tan
  • Yuanzhi Wang
  • Parasit Vectors.2020 Jan;13(1):10. 10.1186/s13071-020-3885-x. doi: 10.1186/s13071-020-3885-x.Epub 2020-01-09.

インテグリンαvβ3を用いた新血管新生のイメージ化のための有望なターゲットとしてのインテグリンαvβ3のインハウスジェネレーター産生ポジトロンエミッター(68)Ga標識DOTA-アルギニン-グリシン-アスパラギン酸(RGD)リガンドを用いた研究

Integrin αvβ3 as a Promising Target to Image Neoangiogenesis Using In-House Generator-Produced Positron Emitter (68)Ga-Labeled DOTA-Arginine-Glycine-Aspartic Acid (RGD) Ligand.
  • Rakhee Vatsa
  • Priya Bhusari
  • Sunil Kumar
  • Sudipta Chakraborty
  • Ashutosh Dash
  • Gurpreet Singh
  • Devinder Kumar Dhawan
  • Jaya Shukla
  • Bhagwant Rai Mittal
  • Cancer Biother. Radiopharm..2015 Jun;30(5):217-24. doi: 10.1089/cbr.2014.1781.

インテグリン(α)vbeta3/焦点接着キナーゼ(FAK)/ホスファチジルイノシトール3-キナーゼ(PI3K)/タンパク質キナーゼB-セリン/スレオニンキナーゼ(AKT)シグナル伝達経路を利用した細胞生存における細胞外マトリックス腎尿細管間質性腎炎抗原(TINag)の役割

Role of extracellular matrix renal tubulo-interstitial nephritis antigen (TINag) in cell survival utilizing integrin (alpha)vbeta3/focal adhesion kinase (FAK)/phosphatidylinositol 3-kinase (PI3K)/protein kinase B-serine/threonine kinase (AKT) signaling pathway.
  • Ping Xie
  • Vinay K Kondeti
  • Sun Lin
  • Yoshisuke Haruna
  • Kirtee Raparia
  • Yashpal S Kanwar
  • J. Biol. Chem..2011 Sep;286(39):34131-46. M111.241778. doi: 10.1074/jbc.M111.241778.Epub 2011-07-27.

感染により誘発されたラットにおけるマクロファージ遊走阻害因子（MIF）発現に及ぼす第一次根絶レジメンへのスネークヘッドフィッシュ抽出物の補充の効果を検討した

The effect of snakehead fish extract supplementation to first-line eradication regimen on macrophage migration inhibitory factor (MIF) expression in rats induced by infection.
  • O K Yulizal
  • Aznan Lelo
  • Syafruddin Ilyas
  • Raden Lia Kusumawati
  • J Adv Vet Anim Res.2020 Jun;7(2):209-217. doi: 10.5455/javar.2020.g411.Epub 2020-05-08.

F-SMBT-1: モノアミン酸化酵素Bイメージングのための選択的かつ可逆的なポジトロン断層撮影トレーサー

F-SMBT-1: A Selective and Reversible Positron-Emission Tomography Tracer for Monoamine Oxidase-B Imaging.
  • Ryuichi Harada
  • Yoshimi Hayakawa
  • Michinori Ezura
  • Pradith Lerdsirisuk
  • Yiqing Du
  • Yoichi Ishikawa
  • Ren Iwata
  • Miho Shidahara
  • Aiko Ishiki
  • Akio Kikuchi
  • Hiroyuki Arai
  • Yukitsuka Kudo
  • Kazuhiko Yanai
  • Shozo Furumoto
  • Nobuyuki Okamura
  • J. Nucl. Med..2020 Jul;jnumed.120.244400. doi: 10.2967/jnumed.120.244400.Epub 2020-07-09.

末梢的に作用するオピオイド受容体拮抗薬ナルデメダインの薬理学的プロフィール。ナロキソンおよびナロキセゴールとの比較

Pharmacological Profile of Naldemedine, a Peripherally Acting -Opioid Receptor Antagonist: Comparison with Naloxone and Naloxegol.
  • Toshiyuki Kanemasa
  • Katsumi Koike
  • Kenji Takase
  • Tohko Arai
  • Atsushi Nakamura
  • Yasuhide Morioka
  • Minoru Hasegawa
  • J. Pharmacol. Exp. Ther..2020 Jun;373(3):438-444. jpet.119.264515. doi: 10.1124/jpet.119.264515.Epub 2020-03-13.

旧・新世界8カ国のコウモリダニ（Acari: Ixodidae, Argasidae）におけるベクター媒介性細菌の分子検出

Molecular detection of vector-borne bacteria in bat ticks (Acari: Ixodidae, Argasidae) from eight countries of the Old and New Worlds.
  • Sándor Hornok
  • Krisztina Szőke
  • Marina L Meli
  • Attila D Sándor
  • Tamás Görföl
  • Péter Estók
  • Yuanzhi Wang
  • Vuong Tan Tu
  • Dávid Kováts
  • Sándor A Boldogh
  • Alexandra Corduneanu
  • Kinga M Sulyok
  • Miklós Gyuranecz
  • Jenő Kontschán
  • Nóra Takács
  • Ali Halajian
  • Sara Epis
  • Regina Hofmann-Lehmann
  • Parasit Vectors.2019 Jan;12(1):50. 10.1186/s13071-019-3303-4. doi: 10.1186/s13071-019-3303-4.Epub 2019-01-22.

EU 域外の L.A.のウイルスおよびビロイドの有害生物分類

Pest categorisation of non-EU viruses and viroids of L.
  • Claude Bragard
  • Katharina Dehnen-Schmutz
  • Paolo Gonthier
  • Marie-Agnès Jacques
  • Josep Anton Jaques Miret
  • Annemarie Fejer Justesen
  • Alan MacLeod
  • Christer Sven Magnusson
  • Panagiotis Milonas
  • Juan A Navas-Cortes
  • Stephen Parnell
  • Roel Potting
  • Philippe Lucien Reignault
  • Hans-Hermann Thulke
  • Wopke Van der Werf
  • Antonio Vicent Civera
  • Jonathan Yuen
  • Lucia Zappalà
  • Thierry Candresse
  • Elisavet Chatzivassiliou
  • Franco Finelli
  • Giovanni Paolo Martelli
  • Stephan Winter
  • Domenico Bosco
  • Michela Chiumenti
  • Francesco Di Serio
  • Tomasz Kaluski
  • Angelantonio Minafra
  • Luisa Rubino
  • EFSA J.2019 Sep;17(9):e05669. EFS25669. doi: 10.2903/j.efsa.2019.5669.Epub 2019-09-30.

パーキンソン病における衝動性に関連した大規模なネットワーク間接続性の増加

Increased large-scale inter-network connectivity in relation to impulsivity in Parkinson's disease.
  • Jinsoo Koh
  • Yoshiki Kaneoke
  • Tomohiro Donishi
  • Takuya Ishida
  • Mayumi Sakata
  • Yasuhiro Hiwatani
  • Yoshiaki Nakayama
  • Masaaki Yasui
  • Hiroshi Ishiguchi
  • Masaya Hironishi
  • Ken-Ya Murata
  • Masaki Terada
  • Hidefumi Ito
  • Sci Rep.2020 Jul;10(1):11418. 10.1038/s41598-020-68266-x. doi: 10.1038/s41598-020-68266-x.Epub 2020-07-10.

間隔盲腸手術は本当に必要か？複雑な虫垂炎を合併した後に間隔をあけて盲腸手術を受けた成人患者の新生物率を詳しく見てみましょう

Is interval appendectomy really needed? A closer look at neoplasm rates in adult patients undergoing interval appendectomy after complicated appendicitis.
  • Danielle Hayes
  • Shelby Reiter
  • Edard Hagen
  • Gary Lucas
  • Isabelle Chu
  • Tobias Muñiz
  • Ryan Martinez
  • Surg Endosc.2020 Jul;10.1007/s00464-020-07798-9. doi: 10.1007/s00464-020-07798-9.Epub 2020-07-16.

Roux-en-Y再建を伴う胃全摘術後の空腸近位部非吻合性狭窄に対する磁気圧迫吻合術：症例報告

Magnetic compression anastomosis for non-anastomotic stenosis of the proximal jejunum after total gastrectomy with Roux-en-Y reconstruction: a case report.
  • Teppei Kamada
  • Hironori Ohdaira
  • Hideyuki Takeuchi
  • Junji Takahashi
  • Rui Marukuchi
  • Norihiko Suzuki
  • Satoshi Narihiro
  • Sojun Hoshimoto
  • Masashi Yoshida
  • Eigoro Yamanouchi
  • Yutaka Suzuki
  • Surg Case Rep.2020 Jul;6(1):167. 10.1186/s40792-020-00932-8. doi: 10.1186/s40792-020-00932-8.Epub 2020-07-09.

中国東北部の下痢性動物から分離されたProteus mirabilisのバイオフィルム形成、病原性遺伝子発現、抗生物質耐性との関連

Association among biofilm formation, virulence gene expression, and antibiotic resistance in Proteus mirabilis isolates from diarrhetic animals in Northeast China.
  • Yadong Sun
  • Shanshan Wen
  • Lili Zhao
  • Qiqi Xia
  • Yue Pan
  • Hanghang Liu
  • Chengwei Wei
  • Hongyan Chen
  • Junwei Ge
  • Hongbin Wang
  • BMC Vet. Res..2020 Jun;16(1):176. 10.1186/s12917-020-02372-w. doi: 10.1186/s12917-020-02372-w.Epub 2020-06-05.

Phanerochaete carnosaのミトコンドリアゲノムは206kbpであり、イントロンの動態、繰り返し配列の蓄積、プラスミド由来の遺伝子などが明らかになっている

The 206 kbp mitochondrial genome of Phanerochaete carnosa reveals dynamics of introns, accumulation of repeat sequences and plasmid-derived genes.
  • Xu Wang
  • Andong Song
  • Fengqin Wang
  • Mingyue Chen
  • Xiao Li
  • Qiang Li
  • Na Liu
  • Int. J. Biol. Macromol..2020 Jun;162:209-219. S0141-8130(20)33586-8. doi: 10.1016/j.ijbiomac.2020.06.142.Epub 2020-06-18.

胃癌に対するBillroth Ⅰ再建術による遠位胃切除術後の逆流性食道炎に塩酸アコチアミドが有効であった1例

[A Case in Which Acotiamide Hydrochloride Was Effective for Reflux Esophagitis after Distal Gastrectomy with Billroth Ⅰ Reconstruction for Gastric Cancer].
  • Yukio Maezawa
  • Toru Aoyama
  • Junya Morita
  • Kazuki Kano
  • Shinya Amano
  • Sho Sawazaki
  • Masakatsu Numata
  • Tsutomu Hayashi
  • Takanobu Yamada
  • Tsutomu Sato
  • Takashi Ohshima
  • Norio Yukawa
  • Takaki Yoshikawa
  • Munetaka Masuda
  • Yasushi Rino
  • Gan To Kagaku Ryoho.2019 Mar;46(3):595-597.

皮質拡散性脱分極により誘発される顔面痛覚過敏、羞明、運動機能低下は、スマトリプタンとオルセゲパントにより改善される

Cortical spreading depolarisation-induced facial hyperalgesia, photophobia and hypomotility are ameliorated by sumatriptan and olcegepant.
  • Chunhua Tang
  • Miyuki Unekawa
  • Satoshi Kitagawa
  • Tsubasa Takizawa
  • Yohei Kayama
  • Jin Nakahara
  • Mamoru Shibata
  • Sci Rep.2020 Jul;10(1):11408. 10.1038/s41598-020-67948-w. doi: 10.1038/s41598-020-67948-w.Epub 2020-07-10.

m-トリフルオロメチルジフェニルジセレニド（m-CF-PhSe）は、海馬の神経毒性適応を調節し、マウスの短期モルヒネ離脱における抑うつ症状に似た表現型を廃止する

m-Trifluoromethyl-diphenyl diselenide (m-CF-PhSe) modulates the hippocampal neurotoxic adaptations and abolishes a depressive-like phenotype in a short-term morphine withdrawal in mice.
  • Carolina C Martins
  • Suzan G Rosa
  • Ana M S Recchi
  • Cristina W Nogueira
  • Gilson Zeni
  • Prog. Neuropsychopharmacol. Biol. Psychiatry.2020 03;98:109803. S0278-5846(19)30576-7. doi: 10.1016/j.pnpbp.2019.109803.Epub 2019-11-02.

RITA仮浸漬系で培養したBENTH.の成長および二次代謝物蓄積に及ぼすスペルミンおよび窒素欠乏の影響

Influence of spermine and nitrogen deficiency on growth and secondary metabolites accumulation in Benth. cultured in a RITA temporary immersion system.
  • Elizabeth Rubio-Rodríguez
  • Alma Rosa López-Laredo
  • Virginia Medina-Pérez
  • Gabriela Trejo-Tapia
  • José Luis Trejo-Espino
  • Eng. Life Sci..2019 Dec;19(12):944-954. ELSC1261. doi: 10.1002/elsc.201900040.Epub 2019-09-19.

消化管微生物群集の変化は、免疫チェックポイント遮断に対するHIV特異的CD8+ T細胞の反応性に影響を与える

Changes in gastrointestinal microbial communities influence HIV-specific CD8+ T-cell responsiveness to immune checkpoint blockade.
  • Ivo N SahBandar
  • Glen M Chew
  • Michael J Corley
  • Alina P S Pang
  • Naoky Tsai
  • Nancy Hanks
  • Vedbar S Khadka
  • Nichole R Klatt
  • Tiffany Hensley-McBain
  • Ma Somsouk
  • Ivan Vujkovic-Cvijin
  • Dominic C Chow
  • Cecilia M Shikuma
  • Lishomwa C Ndhlovu
  • AIDS.2020 Aug;34(10):1451-1460. 00002030-202008010-00003. doi: 10.1097/QAD.0000000000002557.

キュミル-5F-P7AICAを用いた7-アザインドール由来合成カンナビノイドの代謝パターン解明のためのin vitroモデルとin vivoモデルの比較

Comparison of in vitro and in vivo models for the elucidation of metabolic patterns of 7-azaindole-derived synthetic cannabinoids exemplified using cumyl-5F-P7AICA.
  • Nadja Walle
  • Frederike Nordmeier
  • Adrian A Doerr
  • Benjamin Peters
  • Matthias W Laschke
  • Michael D Menger
  • Peter H Schmidt
  • Markus R Meyer
  • Nadine Schaefer
  • Drug Test Anal.2020 Jul;doi: 10.1002/dta.2899.Epub 2020-07-17.