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日本語AIでPubMedを検索

日本語AIでPubMedを検索

PubMedの提供する医学論文データベースを日本語で検索できます。AI(Deep Learning)を活用した機械翻訳エンジンにより、精度高く日本語へ翻訳された論文をご参照いただけます。

みんなが読んでいる論文

補完代替医療(CAM)の医師の態度と認識。多拠点イタリアの研究

Physician Attitudes and Perceptions of Complementary and Alternative Medicine (CAM): A Multicentre Italian Study.
  • Massimiliano Berretta
  • Luca Rinaldi
  • Rosaria Taibi
  • Paolo Tralongo
  • Alberto Fulvi
  • Vincenzo Montesarchio
  • Giordano Madeddu
  • Paolo Magistri
  • Sabrina Bimonte
  • Marco Trovò
  • Patrizia Gnagnarella
  • Arturo Cuomo
  • Marco Cascella
  • Arben Lleshi
  • Guglielmo Nasti
  • Sergio Facchini
  • Francesco Fiorica
  • Raffaele Di Francia
  • Giuseppe Nunnari
  • Giovanni Francesco Pellicanò
  • Aurelio Guglielmino
  • Marco Danova
  • Sabrina Rossetti
  • Alfonso Amore
  • Anna Crispo
  • Gaetano Facchini
  • Front Oncol.2020;10:594. doi: 10.3389/fonc.2020.00594.Epub 2020-04-28.

プロゲステロン受容体を選択的に阻害した骨粗鬆症細胞を持つマウスのコラーゲン誘導性関節炎に対する高い感受性

High susceptibility to collagen-induced arthritis in mice with progesterone receptors selectively inhibited in osteoprogenitor cells.
  • Lixian Liu
  • Junjing Jia
  • Min Jiang
  • Xueping Liu
  • Chenling Dai
  • Barton L Wise
  • Nancy E Lane
  • Wei Yao
  • Arthritis Res. Ther..2020 Jul;22(1):165. 10.1186/s13075-020-02242-8. doi: 10.1186/s13075-020-02242-8.Epub 2020-07-02.

遺伝性心疾患における二次的所見:表現型、行動、心理社会的転帰を評価するための遺伝子型第一原理研究

Secondary findings in inherited heart conditions: a genotype-first feasibility study to assess phenotype, behavioural and psychosocial outcomes.
  • Elizabeth Ormondroyd
  • Andrew R Harper
  • Kate L Thomson
  • Michael P Mackley
  • Jennifer Martin
  • Christopher J Penkett
  • Silvia Salatino
  • Hannah Stark
  • Jonathan Stephens
  • Hugh Watkins
  • Eur. J. Hum. Genet..2020 Jul;10.1038/s41431-020-0694-9. doi: 10.1038/s41431-020-0694-9.Epub 2020-07-20.

都市排水中の14種類のサイトスタティックスを迅速に定量し、水生生物相への影響を調べるための簡単なツールとして液-液抽出を行いました

Liquid-liquid extraction as a simple tool to quickly quantify fourteen cytostatics in urban wastewaters and access their impact in aquatic biota.
  • Teresa I A Gouveia
  • Adrián M T Silva
  • Ana R Ribeiro
  • Arminda Alves
  • Mónica S F Santos
  • Sci. Total Environ..2020 Jun;740:139995. S0048-9697(20)33515-4. doi: 10.1016/j.scitotenv.2020.139995.Epub 2020-06-05.

アケボノハエのマリナー要素の進化史から、昆虫からのトランスポゾンが刺胞動物であるヒドラ・バルガリスのゲノムに水平移動していることが明らかになった

The evolutionary history of mariner elements in stalk-eyed flies reveals the horizontal transfer of transposons from insects into the genome of the cnidarian Hydra vulgaris.
  • C Alastair Grace
  • Martin Carr
  • PLoS ONE.2020;15(7):e0235984. PONE-D-20-11398. doi: 10.1371/journal.pone.0235984.Epub 2020-07-13.

アサロン酸は、IL-4Rα-Tyk2-STAT6とGLUT1-Akt-mTOR-AMPKの協調的シグナル伝達の形成を阻害することにより、グルコース誘発M2分極を阻害した

Asaronic Acid Inhibited Glucose-Triggered M2-Phenotype Shift Through Disrupting the Formation of Coordinated Signaling of IL-4Rα-Tyk2-STAT6 and GLUT1-Akt-mTOR-AMPK.
  • Hyeongjoo Oh
  • Sin-Hye Park
  • Min-Kyung Kang
  • Yun-Ho Kim
  • Eun-Jung Lee
  • Dong Yeon Kim
  • Soo-Il Kim
  • Su Yeon Oh
  • Woojin Na
  • Soon Sung Lim
  • Young-Hee Kang
  • Nutrients.2020 Jul;12(7). E2006. doi: 10.3390/nu12072006.Epub 2020-07-06.

70歳までの骨髄腫におけるボルテゾミブを用いた導入療法、高用量メルファラン、レナリドミド維持療法

Bortezomib-based induction, high-dose melphalan and lenalidomide maintenance in myeloma up to 70 years of age.
  • Elias K Mai
  • Kaya Miah
  • Uta Bertsch
  • Jan Dürig
  • Christof Scheid
  • Katja C Weisel
  • Christina Kunz
  • Markus Munder
  • Hans-Walter Lindemann
  • Maximilian Merz
  • Dirk Hose
  • Anna Jauch
  • Anja Seckinger
  • Steffen Luntz
  • Sandra Sauer
  • Stephan Fuhrmann
  • Peter Brossart
  • Ahmet Elmaagacli
  • Martin Goerner
  • Helga Bernhard
  • Martin Hoffmann
  • Marc S Raab
  • Igor W Blau
  • Mathias Hänel
  • Axel Benner
  • Hans J Salwender
  • Hartmut Goldschmidt
  • Leukemia.2020 Jul;10.1038/s41375-020-0976-9. doi: 10.1038/s41375-020-0976-9.Epub 2020-07-20.

15q13.3に位置するFAN1に共通する変異は、漢民族における統合失調症と双極性障害のリスクを示唆する

Common variants in FAN1, located in 15q13.3, confer risk for schizophrenia and bipolar disorder in Han Chinese.
  • Xuemin Jian
  • Jianhua Chen
  • Zhiqiang Li
  • Aamir Fahira
  • Weihuan Shao
  • Juan Zhou
  • Ke Wang
  • Yanqin Wen
  • Jinmai Zhang
  • Qiangzhen Yang
  • Dun Pan
  • Zhuo Wang
  • Yongyong Shi
  • Prog. Neuropsychopharmacol. Biol. Psychiatry.2020 Dec;103:109973. S0278-5846(20)30289-X. doi: 10.1016/j.pnpbp.2020.109973.Epub 2020-05-22.

小脳出血性脳梗塞後の逆行性栄養管移動を伴う口蓋咽喉頭ミオクローヌス:肥大性小葉変性症の症例報告とレビュー.

Palato-pharyngo-laryngeal myoclonus with recurrent retrograde feeding tube migration after cerebellar hemorrhagic stroke: a case report and review of hypertrophic olivary degeneration.
  • Jamie L Fleet
  • Ronelle Calver
  • Gihan C Perera
  • Zhihui Deng
  • BMC Neurol.2020 Jun;20(1):222. 10.1186/s12883-020-01800-6. doi: 10.1186/s12883-020-01800-6.Epub 2020-06-03.

培養ヒト歯根膜細胞は、複数の骨刺激性サイトカインや成長因子を構成的に発現しており、そのうちのいくつかは機械的変形に反応します

Cultured human periodontal ligament cells constitutively express multiple osteotropic cytokines and growth factors, several of which are responsive to mechanical deformation.
  • Mark N Pinkerton
  • David C Wescott
  • Benjamin J Gaffey
  • Kyle T Beggs
  • Trudy J Milne
  • Murray C Meikle
  • J. Periodont. Res..2008 Jun;43(3):343-51. JRE1040. doi: 10.1111/j.1600-0765.2007.01040.x.Epub 2007-12-17.

新規なB型肝炎ウイルスのカプシド集合体モジュレーターは、強力な抗ウイルス応答を誘導し、ヒト化マウスにおいても

Novel Hepatitis B Virus Capsid Assembly Modulator Induces Potent Antiviral Responses and in Humanized Mice.
  • Franck Amblard
  • Sebastien Boucle
  • Leda Bassit
  • Bryan Cox
  • Ozkan Sari
  • Sijia Tao
  • Zhe Chen
  • Tugba Ozturk
  • Kiran Verma
  • Olivia Russell
  • Virgile Rat
  • Hugues de Rocquigny
  • Oriane Fiquet
  • Maud Boussand
  • James Di Santo
  • Helene Strick-Marchand
  • Raymond F Schinazi
  • Antimicrob. Agents Chemother..2020 01;64(2). e01701-19. doi: 10.1128/AAC.01701-19.Epub 2020-01-27.

ラムダシアロトリンに曝露したOreochromis niloticus魚とタイムパウダー(Thymus vulgaris L.)を同時に給与した場合の免疫学的および酸化反応の二重反応。ストレスと免疫をコードする遺伝子の発現

Dual immunological and oxidative responses in Oreochromis niloticus fish exposed to lambda cyhalothrin and concurrently fed with Thyme powder (Thymus vulgaris L.): Stress and immune encoding gene expression.
  • Samah R Khalil
  • Yasser Abd Elhakim
  • Amir H Abd El-Fattah
  • Mayada Ragab Farag
  • Noura E Abd El-Hameed
  • Abd Elhakeem El-Murr
  • Fish Shellfish Immunol..2020 May;100:208-218. S1050-4648(20)30167-4. doi: 10.1016/j.fsi.2020.03.009.Epub 2020-03-09.

次世代を守る。生殖器からの共生細菌がボブテールイカの卵を真菌のファウリングから保護する

Shielding the Next Generation: Symbiotic Bacteria from a Reproductive Organ Protect Bobtail Squid Eggs from Fungal Fouling.
  • Allison H Kerwin
  • Samantha M Gromek
  • Andrea M Suria
  • Robert M Samples
  • Dister J Deoss
  • Kerry O'Donnell
  • Salvatore Frasca
  • Deanna A Sutton
  • Nathan P Wiederhold
  • Marcy J Balunas
  • Spencer V Nyholm
  • mBio.2019 10;10(5). e02376-19. doi: 10.1128/mBio.02376-19.Epub 2019-10-29.

窒素含有ビスフォスフォネートの骨への作用を調節します

regulates the action of nitrogen-containing bisphosphonates on bone.
  • Lauren E Surface
  • Damon T Burrow
  • Jinmei Li
  • Jiwoong Park
  • Sandeep Kumar
  • Cheng Lyu
  • Niki Song
  • Zhou Yu
  • Abbhirami Rajagopal
  • Yangjin Bae
  • Brendan H Lee
  • Steven Mumm
  • Charles C Gu
  • Jonathan C Baker
  • Mahshid Mohseni
  • Melissa Sum
  • Margaret Huskey
  • Shenghui Duan
  • Vinieth N Bijanki
  • Roberto Civitelli
  • Michael J Gardner
  • Chris M McAndrew
  • William M Ricci
  • Christina A Gurnett
  • Kathryn Diemer
  • Fei Wan
  • Christina L Costantino
  • Kristen M Shannon
  • Noopur Raje
  • Thomas B Dodson
  • Daniel A Haber
  • Jan E Carette
  • Malini Varadarajan
  • Thijn R Brummelkamp
  • Kivanc Birsoy
  • David M Sabatini
  • Gabe Haller
  • Timothy R Peterson
  • Sci Transl Med.2020 May;12(544). eaav9166. doi: 10.1126/scitranslmed.aav9166.

ミラベグロンの安全性と有効性:ミラベグロン、抗ムスカリン薬、プラセボを投与されている過活動膀胱患者を対象とした大規模統合臨床試験データベースの解析」についての編集コメント

Editorial commentary on "Safety and Efficacy of Mirabegron: Analysis of a Large Integrated Clinical Trial Database of Patients with Overactive Bladder Receiving Mirabegron, Antimuscarinics, or Placebo".
  • Tomonori Yamanishi
  • Tomohiko Kamasasko
  • Kanya Kaga
  • Miki Fuse
  • Transl Androl Urol.2020 Jun;9(3):1009-1012. tau-09-03-1009. doi: 10.21037/tau-2020-02.

硫酸インドキシルの濃度と時間は、アリール炭化水素受容体を介してNFATc1を制御し、破骨細胞形成に影響を与えることを明らかにした

Concentration and Duration of Indoxyl Sulfate Exposure Affects Osteoclastogenesis by Regulating NFATc1 via Aryl Hydrocarbon Receptor.
  • Wen-Chih Liu
  • Jia-Fwu Shyu
  • Paik Seong Lim
  • Te-Chao Fang
  • Chien-Lin Lu
  • Cai-Mei Zheng
  • Yi-Chou Hou
  • Chia-Chao Wu
  • Yuh-Feng Lin
  • Kuo-Cheng Lu
  • Int J Mol Sci.2020 May;21(10). E3486. doi: 10.3390/ijms21103486.Epub 2020-05-15.

地域保健センターを紹介している女性の中で、人口統計学的特徴と妊娠の試みと産後うつと不安との間の関連性。A Cross Sectional Study

The Association Between Demographic Characteristics and Attempting of Pregnancy with Postpartum Depression and Anxiety Among Women Referring to Community Health Centres: A Cross Sectional Study.
  • Maryam Alikamali
  • Sedigheh Khodabandeh
  • Maryam Motesaddi
  • Zeinab Bagheri
  • Mohammad Ali Esmaeili
  • Malays J Med Sci.2020 May;27(3):93-104. 10mjms2703_oa7. doi: 10.21315/mjms2020.27.3.10.Epub 2020-06-30.

骨単光子放出型コンピュータ断層撮影/コンピュータ断層撮影を用いた早期変形性関節症を伴う内側メニスカス後根部断裂の修復の予後予測.

Predicting outcome of repair of medial meniscus posterior root tear with early osteoarthritis using bone single-photon emission computed tomography/computed tomography.
  • Wonseok Whi
  • Jae-Young Park
  • Hongyoon Choi
  • Jin Chul Paeng
  • Gi Jeong Cheon
  • Keon Wook Kang
  • Dong Soo Lee
  • Hyuk-Soo Han
  • Medicine (Baltimore).2020 Jul;99(27):e21047. 00005792-202007020-00109. doi: 10.1097/MD.0000000000021047.

中国人ファンコニー貧血患者の表現型と遺伝的基盤を網羅的に解析:悲惨な結果から全国的な研究が求められている

Comprehensive analysis on phenotype and genetic basis of Chinese Fanconi anemia patients: dismal outcomes call for nationwide studies.
  • Daijing Nie
  • Jing Zhang
  • Fang Wang
  • Wei Zhang
  • Lili Liu
  • Xue Chen
  • Yang Zhang
  • Panxiang Cao
  • Min Xiong
  • Tong Wang
  • Ping Wu
  • Xiaoli Ma
  • Wenjun Tian
  • Mangju Wang
  • Kylan N Chen
  • Hongxing Liu
  • BMC Med. Genet..2020 Jun;21(1):118. 10.1186/s12881-020-01057-3. doi: 10.1186/s12881-020-01057-3.Epub 2020-06-01.

ブラジルの3つの湿地に生息する水鳥におけるヘモスポリジアンの多様性と有病率の空間分布に及ぼすベクターの生息地適性、環境要因、宿主特性の影響

Effects of habitat suitability for vectors, environmental factors and host characteristics on the spatial distribution of the diversity and prevalence of haemosporidians in waterbirds from three Brazilian wetlands.
  • Samira Chahad-Ehlers
  • Angela Terumi Fushita
  • Gustavo Augusto Lacorte
  • Pamela Carla Pereira de Assis
  • Silvia Nassif Del Lama
  • Parasit Vectors.2018 05;11(1):276. 10.1186/s13071-018-2847-z. doi: 10.1186/s13071-018-2847-z.Epub 2018-05-02.

副腎皮質がんを対象とした新規副腎特異的ステロールO-アシルトランスフェラーゼ1(SOAT1)阻害剤ネバニミベ塩酸塩の第1相試験

A phase 1 study of nevanimibe HCl, a novel adrenal-specific sterol O-acyltransferase 1 (SOAT1) inhibitor, in adrenocortical carcinoma.
  • David C Smith
  • Matthias Kroiss
  • Electron Kebebew
  • Mouhammed Amir Habra
  • Rashmi Chugh
  • Bryan J Schneider
  • Martin Fassnacht
  • Pegah Jafarinasabian
  • M Marian Ijzerman
  • Vivian H Lin
  • Pharis Mohideen
  • Aung Naing
  • Invest New Drugs.2020 Jan;10.1007/s10637-020-00899-1. doi: 10.1007/s10637-020-00899-1.Epub 2020-01-27.

ファーストコンタクト。7-フェニル-2-アミノキノリン、イソフォーム特異的なアスパラギン酸を標的とした強力かつ選択的な神経性一酸化窒素合成酵素阻害剤

First Contact: 7-Phenyl-2-Aminoquinolines, Potent and Selective Neuronal Nitric Oxide Synthase Inhibitors That Target an Isoform-Specific Aspartate.
  • Maris A Cinelli
  • Cory T Reidl
  • Huiying Li
  • Georges Chreifi
  • Thomas L Poulos
  • Richard B Silverman
  • J. Med. Chem..2020 May;63(9):4528-4554. doi: 10.1021/acs.jmedchem.9b01573.Epub 2020-04-17.

アノオクタミン-1阻害活性を有するTrigonostemon honbaensis由来の置換トルキシン酸の4つの新規なショ糖ジエステル

Four new sucrose diesters of substituted truxinic acids from Trigonostemon honbaensis with their anoctamin-1 inhibitory activity.
  • Ninh Khac Ban
  • Luu Hong Truong
  • Tran Van Tiep
  • Duong Thi Hai Yen
  • Vu Van Doan
  • Nguyen Xuan Nhiem
  • Yohan Seo
  • Wan Namkung
  • Seung Hyun Kim
  • Bui Huu Tai
  • Phan Van Kiem
  • Bioorg. Chem..2020 Jun;102:104058. S0045-2068(20)31355-9. doi: 10.1016/j.bioorg.2020.104058.Epub 2020-06-30.

空腹時血清総胆汁酸値は、2型糖尿病患者におけるグルコースチャレンジに対するインスリン感受性、膵島β細胞機能、およびグルカゴンレベルと関連している

Fasting serum total bile acid levels are associated with insulin sensitivity, islet β-cell function and glucagon levels in response to glucose challenge in patients with type 2 diabetes.
  • Xiao-Hua Wang
  • Feng Xu
  • Ming Cheng
  • Xing Wang
  • Dong-Mei Zhang
  • Li-Hua Zhao
  • Hong-Li Cai
  • Hai-Yan Huang
  • Tong Chen
  • Xiu-Lin Zhang
  • Xue-Qin Wang
  • Xing-Bo Cheng
  • Jian-Bin Su
  • Yan Lu
  • Endocr. J..2020 Jul;doi: 10.1507/endocrj.EJ20-0201.Epub 2020-07-17.

アストロサイトヒストン脱アセチル化酵素2は、グルタミン酸トランスポーター1をネガティブに制御することで、くも膜下出血後の遅発性抑うつと記憶障害を促進する

Astrocytic histone deacetylase 2 facilitates delayed depression and memory impairment after subarachnoid hemorrhage by negatively regulating glutamate transporter-1.
  • Kai Tao
  • Qing Cai
  • Xudong Zhang
  • Lin Zhu
  • Zhenru Liu
  • Fei Li
  • Qiang Wang
  • Lei Liu
  • Dayun Feng
  • Ann Transl Med.2020 Jun;8(11):691. atm-08-11-691. doi: 10.21037/atm-20-4330.

熱的に安定な有機金属ハライドペロブスカイトマイクロロッドのサイズ成長制御。二重ドーピング、格子ひずみ工学、反溶媒結晶化、バンドギャップ調整特性の相乗効果

Controlled Size Growth of Thermally Stable Organometallic Halide Perovskite Microrods: Synergistic Effect of Dual-Doping, Lattice Strain Engineering, Antisolvent Crystallization, and Band Gap Tuning Properties.
  • Mohammed Nazim
  • Jae Hyun Kim
  • ACS Omega.2020 Jul;5(26):16106-16119. doi: 10.1021/acsomega.0c01667.Epub 2020-06-22.

進行性皮膚線維症は、ヨーロッパの強皮症試験研究(EUSTAR)コホートにおけるびまん性皮膚全身性硬化症患者の肺機能の低下および生存率の悪化と関連している

Progressive skin fibrosis is associated with a decline in lung function and worse survival in patients with diffuse cutaneous systemic sclerosis in the European Scleroderma Trials and Research (EUSTAR) cohort.
  • Wanlong Wu
  • Suzana Jordan
  • Nicole Graf
  • Janethe de Oliveira Pena
  • John Curram
  • Yannick Allanore
  • Marco Matucci-Cerinic
  • Janet E Pope
  • Christopher P Denton
  • Dinesh Khanna
  • Oliver Distler
  • Ann. Rheum. Dis..2019 05;78(5):648-656. annrheumdis-2018-213455. doi: 10.1136/annrheumdis-2018-213455.Epub 2019-03-09.

AHR1-ARNT1二量化ペアは、ニワトリにおいて、天然リガンドに対する反応の主要な調節因子であるが、TCDDに対する反応性はないことがわかった

The AHR1-ARNT1 dimerization pair is a major regulator of the response to natural ligands, but not to TCDD, in the chicken.
  • Dong-Hee Koh
  • Ji-Hee Hwang
  • Jae-Gon Park
  • Woo-Seon Song
  • Hisato Iwata
  • Eun-Young Kim
  • Ecotoxicol. Environ. Saf..2020 Sep;201:110835. S0147-6513(20)30674-6. doi: 10.1016/j.ecoenv.2020.110835.Epub 2020-06-17.

嚢胞性線維症患者におけるILC2の肺ホーミング。CCR6の機能的関与と呼吸不全への影響

ILC2 Lung-Homing in Cystic Fibrosis Patients: Functional Involvement of CCR6 and Impact on Respiratory Failure.
  • Anja Schulz-Kuhnt
  • Vicky Greif
  • Kai Hildner
  • Lisa Knipfer
  • Michael Döbrönti
  • Sabine Zirlik
  • Florian Fuchs
  • Raja Atreya
  • Sebastian Zundler
  • Rocío López-Posadas
  • Clemens Neufert
  • Andreas Ramming
  • Alexander Kiefer
  • Anika Grüneboom
  • Erwin Strasser
  • Stefan Wirtz
  • Markus F Neurath
  • Imke Atreya
  • Front Immunol.2020;11:691. doi: 10.3389/fimmu.2020.00691.Epub 2020-05-07.

Kv1.3はパーキンソン病における神経炎症と神経変性を調節している

Kv1.3 modulates neuroinflammation and neurodegeneration in Parkinson's disease.
  • Souvarish Sarkar
  • Hai M Nguyen
  • Emir Malovic
  • Jie Luo
  • Monica Langley
  • Bharathi N Palanisamy
  • Neeraj Singh
  • Sireesha Manne
  • Matthew Neal
  • Michelle Gabrielle
  • Ahmed Abdalla
  • Poojya Anantharam
  • Dharmin Rokad
  • Nikhil Panicker
  • Vikrant Singh
  • Muhammet Ay
  • Adhithiya Charli
  • Dilshan Harischandra
  • Lee-Way Jin
  • Huajun Jin
  • Srikant Rangaraju
  • Vellareddy Anantharam
  • Heike Wulff
  • Anumantha G Kanthasamy
  • J. Clin. Invest..2020 Jun;136174. doi: 10.1172/JCI136174.Epub 2020-06-29.

慢性大腸炎誘発性内臓痛は、静穏期の不安感の増加と関連している

Chronic colitis-induced visceral pain is associated with increased anxiety during quiescent phase.
  • Emmeline Salameh
  • Mathieu Meleine
  • Guillaume Gourcerol
  • Jean-Claude do Rego
  • Jean-Luc do Rego
  • Romain Legrand
  • Jonathan Breton
  • Moutaz Aziz
  • Charlène Guérin
  • Moïse Coëffier
  • Guillaume Savoye
  • Rachel Marion-Letellier
  • Am. J. Physiol. Gastrointest. Liver Physiol..2019 06;316(6):G692-G700. doi: 10.1152/ajpgi.00248.2018.Epub 2019-02-08.

チモキノン(2-イソプロピル-5-メチル-1,4-ベンゾキノン)の化学予防・抗がん剤としての作用。化学と生物学的効果

Thymoquinone (2-Isoprpyl-5-methyl-1, 4-benzoquinone) as a chemopreventive/anticancer agent: Chemistry and biological effects.
  • Anas Ahmad
  • Rakesh Kumar Mishra
  • Akshay Vyawahare
  • Ajay Kumar
  • Muneeb U Rehman
  • Wajhul Qamar
  • Abdul Quaiyoom Khan
  • Rehan Khan
  • Saudi Pharm J.2019 Dec;27(8):1113-1126. S1319-0164(19)30122-7. doi: 10.1016/j.jsps.2019.09.008.Epub 2019-09-25.

実験的チャレンジの際に、従来の仔羊を対象としたいくつかの自家産および/または市販のワクチン接種プログラムによって与えられたコリバチルス症に対する保護のレベルの評価

An Assessment of the Level of Protection Against Colibacillosis Conferred by Several Autogenous and/or Commercial Vaccination Programs in Conventional Pullets upon Experimental Challenge.
  • Dimitris Koutsianos
  • Hubert Gantelet
  • Giovanni Franzo
  • Mathilde Lecoupeur
  • Eric Thibault
  • Mattia Cecchinato
  • Konstantinos C Koutoulis
  • Vet Sci.2020 Jun;7(3). E80. doi: 10.3390/vetsci7030080.Epub 2020-06-30.

遠隔虚血性前処理は、経皮的冠動脈造影を受ける中等度の腎障害を有する患者における造影誘発性腎症のリスクを低下させる。メタアナリシス

Remote Ischemic Preconditioning Reduces the Risk of Contrast-Induced Nephropathy in Patients with Moderate Renal Impairment Undergoing Percutaneous Coronary Angiography: A Meta-Analysis.
  • Jin Deng
  • Yi Lu
  • Jihong Ou
  • Xiaofei Shao
  • Xin Wang
  • Hongping Xie
  • Kidney Blood Press. Res..2020 Jul;:1-16. 000507330. doi: 10.1159/000507330.Epub 2020-07-20.

市販の ELISA キット、プロトタイプのマルチプレックス電気化学発光アッセイ、およびマルチプレックスビーズベース免疫測定法による尿由来の膀胱癌関連の診断シグネチャの検出法の比較

Comparison of Commercial ELISA Kits, a Prototype Multiplex Electrochemoluminescent Assay, and a Multiplex Bead-Based Immunoassay for Detecting a Urine-Based Bladder-Cancer-Associated Diagnostic Signature.
  • Hideki Furuya
  • Ian Pagano
  • Keanu Chee
  • Takashi Kobayashi
  • Regan S Wong
  • Riko Lee
  • Charles J Rosser
  • Diagnostics (Basel).2019 Oct;9(4). E166. doi: 10.3390/diagnostics9040166.Epub 2019-10-29.

ヒトIL6STにおける優性陰性突然変異は、高IgE症候群の原因となっています

Dominant-negative mutations in human IL6ST underlie hyper-IgE syndrome.
  • Vivien Béziat
  • Simon J Tavernier
  • Yin-Huai Chen
  • Cindy S Ma
  • Marie Materna
  • Arian Laurence
  • Jens Staal
  • Dominik Aschenbrenner
  • Lisa Roels
  • Lisa Worley
  • Kathleen Claes
  • Lisa Gartner
  • Lisa A Kohn
  • Marieke De Bruyne
  • Klaus Schmitz-Abe
  • Louis-Marie Charbonnier
  • Sevgi Keles
  • Justine Nammour
  • Natasha Vladikine
  • Majistor Raj Luxman Maglorius Renkilaraj
  • Yoann Seeleuthner
  • Mélanie Migaud
  • Jérémie Rosain
  • Mohamed Jeljeli
  • Bertrand Boisson
  • Eva Van Braeckel
  • Jill A Rosenfeld
  • Hongzheng Dai
  • Lindsay C Burrage
  • David R Murdock
  • Bart N Lambrecht
  • Véronique Avettand-Fenoel
  • Tiphanie P Vogel
  • Charles R Esther
  • Sule Haskologlu
  • Figen Dogu
  • Peter Ciznar
  • David Boutboul
  • Marie Ouachée-Chardin
  • Jean Amourette
  • Marie-Noëlle Lebras
  • Clément Gauvain
  • Colas Tcherakian
  • Aydan Ikinciogullari
  • Rudi Beyaert
  • Laurent Abel
  • Joshua D Milner
  • Bodo Grimbacher
  • Louis-Jean Couderc
  • Manish J Butte
  • Alexandra F Freeman
  • Émilie Catherinot
  • Claire Fieschi
  • Talal A Chatila
  • Stuart G Tangye
  • Holm H Uhlig
  • Filomeen Haerynck
  • Jean-Laurent Casanova
  • Anne Puel
  • J. Exp. Med..2020 Jun;217(6). e20191804. doi: 10.1084/jem.20191804.

Toll-like receptor 9 1635A/G多型は、抗レトロウイルス療法を4週間中断した後のHIV-1リバウンドと関連している

Toll-like receptor 9 1635A/G polymorphism is associated with HIV-1 rebound after four weeks of interruption of antiretroviral therapy.
  • Alejandro Vallejo
  • Sonia Molina-Pinelo
  • Beatriz De Felipe
  • María Abad-Fernández
  • María Francisca González-Escribano
  • Manuel Leal
  • Natalia Soriano-Sarabia
  • J. Acquir. Immune Defic. Syndr..2020 Jul;doi: 10.1097/QAI.0000000000002437.Epub 2020-07-08.

筋肉内脂肪細胞のトランスクリプトームネットワークに関連付けられた DNA メチル化の風景は、ニワトリの筋肉内脂肪沈着の洞察を生成します

The Landscape of DNA Methylation Associated With the Transcriptomic Network of Intramuscular Adipocytes Generates Insight Into Intramuscular Fat Deposition in Chicken.
  • Meng Zhang
  • Donghua Li
  • Yanhui Zhai
  • Zhengzhu Wang
  • Xiangfei Ma
  • Daoyu Zhang
  • Guoxi Li
  • Ruili Han
  • Ruirui Jiang
  • Zhuanjian Li
  • Xiangtao Kang
  • Guirong Sun
  • Front Cell Dev Biol.2020;8:206. doi: 10.3389/fcell.2020.00206.Epub 2020-04-02.

サリニペプチンゲノム解析と化学的アプローチを統合して、グレートソルトレイクのストレプトマイセス属細菌由来の珍しいd-アミノ酸含有リボソーム合成ペプチドと翻訳後修飾ペプチド(RiPPs)を明らかにした

Salinipeptins: Integrated Genomic and Chemical Approaches Reveal Unusual d-Amino Acid-Containing Ribosomally Synthesized and Post-Translationally Modified Peptides (RiPPs) from a Great Salt Lake Streptomyces sp.
  • Zhuo Shang
  • Jaclyn M Winter
  • Christopher A Kauffman
  • Inho Yang
  • William Fenical
  • ACS Chem. Biol..2019 03;14(3):415-425. doi: 10.1021/acschembio.8b01058.Epub 2019-02-26.

忘れ去られていた9-アクリダノン系ヒドラゾンであるRo 15-5458の有効性,代謝および薬物動態

Efficacy, metabolism and pharmacokinetics of Ro 15-5458, a forgotten schistosomicidal 9-acridanone hydrazone.
  • Alexandra Probst
  • Cécile Häberli
  • Dionicio Siegel
  • Jianbo Huang
  • Seth Vigneron
  • Anh P Ta
  • Danielle E Skinner
  • Nelly El-Sakkary
  • Jeremiah D Momper
  • Jon Gangoiti
  • Yuxiang Dong
  • Jonathan L Vennerstrom
  • Susan A Charman
  • Conor R Caffrey
  • Jennifer Keiser
  • J. Antimicrob. Chemother..2020 Jul;dkaa247. doi: 10.1093/jac/dkaa247.Epub 2020-07-02.

脳卒中発症から4.5時間以上のアルテプラーゼを用いた灌流CTによる静脈内血栓溶解療法

Intravenous Thrombolysis Guided by Perfusion CT with Alteplase in >4.5 Hours from Stroke Onset.
  • Manuel Medina-Rodriguez
  • Manuel Millan-Vazquez
  • Elena Zapata-Arriaza
  • Irene Escudero
  • Blanca Pardo-Galiana
  • Juan Antonio Cabezas-Rodriguez
  • Lucia Lebrato-Hernandez
  • Joaquin Ortega-Quintanilla
  • Asier de Albóniga-Chindurza
  • Rafael Felix Ocete-Perez
  • Juan Jurado-Serrano
  • Alejandro Gonzalez-Garcia
  • Aurelio Cayuela
  • Francisco Moniche
  • Cerebrovasc. Dis..2020 Jul;:1-6. 000509013. doi: 10.1159/000509013.Epub 2020-07-02.

KCNQ2関連てんかん脳症のノックインマウスモデルでは、自発的な全身性発作と認知機能障害が認められた

A knock-in mouse model for KCNQ2-related epileptic encephalopathy displays spontaneous generalized seizures and cognitive impairment.
  • Mathieu Milh
  • Pierre Roubertoux
  • Najoua Biba
  • Julie Chavany
  • Adeline Spiga Ghata
  • Camille Fulachier
  • Stephan Christopher Collins
  • Christel Wagner
  • Jean-Christophe Roux
  • Binnaz Yalcin
  • Marie-Solenne Félix
  • Florence Molinari
  • Pierre-Pascal Lenck-Santini
  • Laurent Villard
  • Epilepsia.2020 May;61(5):868-878. doi: 10.1111/epi.16494.Epub 2020-04-02.

ミトコンドリア神経消化管脳筋症(MNGIE)における肝移植:臨床的長期追跡調査と病原性の示唆

Liver transplantation in mitochondrial neurogastrointestinal encephalomyopathy (MNGIE): clinical long-term follow-up and pathogenic implications.
  • Roberto D'Angelo
  • Elisa Boschetti
  • Giulia Amore
  • Roberta Costa
  • Alessia Pugliese
  • Leonardo Caporali
  • Laura Ludovica Gramegna
  • Valentina Papa
  • Luca Vizioli
  • Mariantonietta Capristo
  • Manuela Contin
  • Susan Mohamed
  • Giovanna Cenacchi
  • Raffaele Lodi
  • Maria Cristina Morelli
  • Luca Fasano
  • Lara Pisani
  • Matteo Cescon
  • Caterina Tonon
  • Antonio Daniele Pinna
  • Maria Teresa Dotti
  • Francesco Sicurelli
  • Mauro Scarpelli
  • Massimiliano Filosto
  • Carlo Casali
  • Loris Pironi
  • Valerio Carelli
  • Roberto De Giorgio
  • Rita Rinaldi
  • J. Neurol..2020 Jul;10.1007/s00415-020-10051-x. doi: 10.1007/s00415-020-10051-x.Epub 2020-07-18.

Phyllanthus amarus Schum. and Thonn.の水抽出物の予防効果(Euphorbiaceae)の水性抽出物のDOCA-塩害による高血圧、心肥大と機能障害、ラットの内皮機能障害に対する予防的効果

Preventive Beneficial Effect of an Aqueous Extract of Phyllanthus amarus Schum. and Thonn. (Euphorbiaceae) on DOCA-Salt-Induced Hypertension, Cardiac Hypertrophy and Dysfunction, and Endothelial Dysfunction in Rats.
  • Nʼguessan Alain Yao
  • Zahid Rasul Niazi
  • Iveta Najmanová
  • Mamadou Kamagaté
  • Amissi Said
  • Philippe Chabert
  • Cyril Auger
  • Henri Die-Kakou
  • Valérie Schini-Kerth
  • J. Cardiovasc. Pharmacol..2020 Jun;75(6):573-583. doi: 10.1097/FJC.0000000000000825.

CR6-interacting factor 1欠損症は、テトラヒドロビオプテリンの生合成を阻害することで、内皮一酸化窒素合成酵素活性を低下させる

CR6-interacting factor 1 deficiency reduces endothelial nitric oxide synthase activity by inhibiting biosynthesis of tetrahydrobiopterin.
  • Ikjun Lee
  • Seonhee Kim
  • Harsha Nagar
  • Su-Jeong Choi
  • Byeong Hwa Jeon
  • Shuyu Piao
  • Cuk-Seong Kim
  • Sci Rep.2020 01;10(1):842. 10.1038/s41598-020-57673-9. doi: 10.1038/s41598-020-57673-9.Epub 2020-01-21.