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日本語AIでPubMedを検索

日本語AIでPubMedを検索

PubMedの提供する医学論文データベースを日本語で検索できます。AI(Deep Learning)を活用した機械翻訳エンジンにより、精度高く日本語へ翻訳された論文をご参照いただけます。

みんなが読んでいる論文

ヒト膵臓癌における細胞浸潤・遊走を制御する細胞外小胞輸送を介した長鎖ノンコーディングRNA HULCとMicroRNA-622の相互作用

The Interaction Between Long Non-coding RNA HULC and MicroRNA-622 via Transfer by Extracellular Vesicles Regulates Cell Invasion and Migration in Human Pancreatic Cancer.
  • Kenji Takahashi
  • Kazuya Koyama
  • Yu Ota
  • Hidetaka Iwamoto
  • Keisuke Yamakita
  • Satoshi Fujii
  • Yohei Kitano
  • Front Oncol.2020;10:1013. doi: 10.3389/fonc.2020.01013.Epub 2020-06-23.

腸骨大腿部深部静脈血栓症の治療におけるAngioJet Pharmacomechanical Thrombectomyおよびカテーテル指示型血栓溶解療法とカテーテル指示型血栓溶解療法のみの比較。単一施設のレトロスペクティブコホート研究

AngioJet Pharmacomechanical Thrombectomy and Catheter Directed Thrombolysis vs. Catheter Directed Thrombolysis Alone for the Treatment of Iliofemoral Deep Vein Thrombosis: A Single Centre Retrospective Cohort Study.
  • Anna L Pouncey
  • Adam M Gwozdz
  • Oscar W Johnson
  • Justinas Silickas
  • Prakash Saha
  • Narayan Thulasidasan
  • Narayan Karunanithy
  • Ander T Cohen
  • Stephen A Black
  • Eur J Vasc Endovasc Surg.2020 Jul;S1078-5884(20)30423-8. doi: 10.1016/j.ejvs.2020.05.006.Epub 2020-07-11.

1.5Tおよび3TでのMRI時の両側DBSインプラント近傍組織のRF誘導加熱:外科的リード管理の役割

RF-induced heating in tissue near bilateral DBS implants during MRI at 1.5 T and 3T: The role of surgical lead management.
  • Laleh Golestanirad
  • John Kirsch
  • Giorgio Bonmassar
  • Sean Downs
  • Behzad Elahi
  • Alastair Martin
  • Maria-Ida Iacono
  • Leonardo M Angelone
  • Boris Keil
  • Lawrence L Wald
  • Julie Pilitsis
  • Neuroimage.2019 01;184:566-576. S1053-8119(18)30819-X. doi: 10.1016/j.neuroimage.2018.09.034.Epub 2018-09-19.

黄斑変性症に対するHLAマッチ同種iPS細胞由来RPE移植

HLA-Matched Allogeneic iPS Cells-Derived RPE Transplantation for Macular Degeneration.
  • Sunao Sugita
  • Michiko Mandai
  • Yasuhiko Hirami
  • Seiji Takagi
  • Tadao Maeda
  • Masashi Fujihara
  • Mitsuhiro Matsuzaki
  • Midori Yamamoto
  • Kyoko Iseki
  • Naoko Hayashi
  • Ayumi Hono
  • Shoko Fujino
  • Naoshi Koide
  • Noriko Sakai
  • Yumiko Shibata
  • Motoki Terada
  • Mitsuhiro Nishida
  • Hiromi Dohi
  • Masaki Nomura
  • Naoki Amano
  • Hirokazu Sakaguchi
  • Chikako Hara
  • Kazuichi Maruyama
  • Takashi Daimon
  • Masataka Igeta
  • Toshihiko Oda
  • Utako Shirono
  • Misato Tozaki
  • Kota Totani
  • Satoshi Sugiyama
  • Kohji Nishida
  • Yasuo Kurimoto
  • Masayo Takahashi
  • J Clin Med.2020 Jul;9(7). E2217. doi: 10.3390/jcm9072217.Epub 2020-07-13.

中等度および重度の過活動膀胱に対する電気鍼治療とソリフェナシンの効果:多施設、無作為化比較試験プロトコール

Effect of electroacupuncture versus solifenacin for moderate and severe overactive bladder: a multi-centre, randomized controlled trial study protocol.
  • Qian Wen
  • Ning Li
  • Xueling Wang
  • Hao Li
  • Fengwei Tian
  • Weiwei Chen
  • Yanyan Lu
  • Zhishun Liu
  • BMC Complement Med Ther.2020 Jul;20(1):224. 10.1186/s12906-020-03018-y. doi: 10.1186/s12906-020-03018-y.Epub 2020-07-16.

神経細胞の塩化物押し出しを強化することで、神経障害性疼痛におけるα2/α3 GABAを介した鎮痛効果を回復させる

Enhancing neuronal chloride extrusion rescues α2/α3 GABA-mediated analgesia in neuropathic pain.
  • Louis-Etienne Lorenzo
  • Antoine G Godin
  • Francesco Ferrini
  • Karine Bachand
  • Isabel Plasencia-Fernandez
  • Simon Labrecque
  • Alexandre A Girard
  • Dominic Boudreau
  • Irenej Kianicka
  • Martin Gagnon
  • Nicolas Doyon
  • Alfredo Ribeiro-da-Silva
  • Yves De Koninck
  • Nat Commun.2020 02;11(1):869. 10.1038/s41467-019-14154-6. doi: 10.1038/s41467-019-14154-6.Epub 2020-02-13.

大動脈平滑筋における電圧依存性KチャネルとSERCAポンプの活性化を介したゲミグリプチンの血管拡張作用

The vasodilatory effect of gemigliptin via activation of voltage-dependent K channels and SERCA pumps in aortic smooth muscle.
  • Hee Seok Jung
  • Mi Seon Seo
  • Jin Ryeol An
  • Minji Kang
  • Ryeon Heo
  • Hongliang Li
  • Won-Kyo Jung
  • Il-Whan Choi
  • Eun-Hee Cho
  • Hongzoo Park
  • Young Min Bae
  • Won Sun Park
  • Eur. J. Pharmacol..2020 Jun;882:173243. S0014-2999(20)30335-6. doi: 10.1016/j.ejphar.2020.173243.Epub 2020-06-12.

雌ニホンウズラの肝臓に及ぼす鉛の慢性曝露の影響:病理組織学的損傷、酸化ストレス、AMP活性化プロテインキナーゼに基づく脂質代謝障害

The effects of chronic lead exposure on the liver of female Japanese quail (Coturnix japonica): Histopathological damages, oxidative stress and AMP-activated protein kinase based lipid metabolism disorder.
  • Honghong Kou
  • Jing Ya
  • Xuebin Gao
  • Hongfeng Zhao
  • Ecotoxicol. Environ. Saf..2020 Mar;190:110055. S0147-6513(19)31386-7. doi: 10.1016/j.ecoenv.2019.110055.Epub 2019-12-12.

KLHL24の不活性化に伴う致死性不整脈を伴う心筋症

Cardiomyopathy with lethal arrhythmias associated with inactivation of KLHL24.
  • Carola Hedberg-Oldfors
  • Alexandra Abramsson
  • Daniel P S Osborn
  • Olof Danielsson
  • Afsoon Fazlinezhad
  • Yalda Nilipour
  • Laila Hübbert
  • Inger Nennesmo
  • Kittichate Visuttijai
  • Jaipreet Bharj
  • Evmorfia Petropoulou
  • Azza Shoreim
  • Barbara Vona
  • Najmeh Ahangari
  • Marcela Dávila López
  • Mohammad Doosti
  • Rakesh Kumar Banote
  • Reza Maroofian
  • Malin Edling
  • Mehdi Taherpour
  • Henrik Zetterberg
  • Ehsan Ghayoor Karimiani
  • Anders Oldfors
  • Yalda Jamshidi
  • Hum. Mol. Genet..2019 06;28(11):1919-1929. 5305756. doi: 10.1093/hmg/ddz032.

中等度から重度の肺疾患を有する嚢胞性線維症患者の気道マイクロバイオームのアンターゲットメタゲノム調査

Untargeted Metagenomic Investigation of the Airway Microbiome of Cystic Fibrosis Patients with Moderate-Severe Lung Disease.
  • Giovanni Bacci
  • Giovanni Taccetti
  • Daniela Dolce
  • Federica Armanini
  • Nicola Segata
  • Francesca Di Cesare
  • Vincenzina Lucidi
  • Ersilia Fiscarelli
  • Patrizia Morelli
  • Rosaria Casciaro
  • Anna Negroni
  • Alessio Mengoni
  • Annamaria Bevivino
  • Microorganisms.2020 Jul;8(7). E1003. doi: 10.3390/microorganisms8071003.Epub 2020-07-04.

使い捨てピペット抽出法と超高速液体クロマトグラフィー・タンデム質量分析法による脳脊髄液試料中のアナンダミドの定量

Determination of anandamide in cerebrospinal fluid samples by disposable pipette extraction and ultra-high performance liquid chromatography tandem mass spectrometry.
  • Igor Gustavo de Carvalho Oliveira
  • Camila Marchioni
  • Maria Eugênia Costa Queiroz
  • J. Chromatogr. B Analyt. Technol. Biomed. Life Sci..2019 Nov;1130-1131:121809. S1570-0232(19)30687-7. doi: 10.1016/j.jchromb.2019.121809.Epub 2019-10-04.

ウィスターラットの実験的に誘発された微小結晶性関節炎における滑膜炎症過程のレーザー治療

Laser treatment of synovial inflammatory process in experimentally induced microcrystalline arthritis in Wistar rats.
  • Débora Mara Fortes Bartoli
  • Airton Luiz Felizatti
  • Fernando Russo Costa do Bomfim
  • Julia Leme Bovo
  • Andrea Aparecida de Aro
  • Maria Esméria Corezzola do Amaral
  • Marcelo Augusto Marretto Esquisatto
  • Lasers Med Sci.2020 Jun;10.1007/s10103-020-03055-6. doi: 10.1007/s10103-020-03055-6.Epub 2020-06-10.

術前の血糖値とヘモグロビンa1c値は、ペニス埋入術を受ける糖尿病男性における術後感染症の予測にはならない

Immediate preoperative blood glucose and hemoglobin a1c levels are not predictive of postoperative infections in diabetic men undergoing penile prosthesis placement.
  • Mohamad M Osman
  • Linda M Huynh
  • Farouk M El-Khatib
  • Maxwell Towe
  • Huang-Wei Su
  • Robert Andrianne
  • Gregory Barton
  • Gregory Broderick
  • Arthur L Burnett
  • Jeffrey D Campbell
  • Jonathan Clavell-Hernandez
  • Jessica Connor
  • Martin Gross
  • Ross Guillum
  • Amy I Guise
  • Georgios Hatzichristodoulou
  • Gerard D Henry
  • Tung-Chin Hsieh
  • Lawrence C Jenkins
  • Christopher Koprowski
  • Kook B Lee
  • Aaron Lentz
  • Ricardo M Munarriz
  • Daniar Osmonov
  • Shu Pan
  • Kevin Parikh
  • Sung Hun Park
  • Amir S Patel
  • Paul Perito
  • Hossein Sadeghi-Nejad
  • Maxime Sempels
  • Jay Simhan
  • Run Wang
  • Faysal A Yafi
  • Int. J. Impot. Res..2020 Mar;10.1038/s41443-020-0261-5. doi: 10.1038/s41443-020-0261-5.Epub 2020-03-20.

カメルーン産の食用・薬用キノコPleurotus tuber-regium(Agaricomycetes)の粗抽出物の抗真菌・抗菌活性の比較評価

Comparative Assessment of Antifungal and Antibacterial Activities of Crude Extracts of the King Tuber Culinary-Medicinal Mushroom, Pleurotus tuber-regium (Agaricomycetes) from Cameroon.
  • Blondo-Pascal Metsebing
  • Romuald Oba
  • Dominique Claude Mossebo
  • Thierry Youmbi Fonkui
  • Fabrice Tsigaing Tsigain
  • Marthe Carine Djuidje Fotsing
  • Tata Charlotte Mungoh
  • Derek Ntantoh Ndinteh
  • Int J Med Mushrooms.2020;22(4):359-366. 742ee6254aa2c7db,25f63c9a2c43158e. doi: 10.1615/IntJMedMushrooms.2020034178.

シグナル伝達型アダプター蛋白質-2は、造血ストレス時のB系統リンパ球の回復を遅延させる

Signal-transducing adaptor protein-2 delays recovery of B lineage lymphocytes during hematopoietic stress.
  • Michiko Ichii
  • Kenji Oritani
  • Jun Toda
  • Hideaki Saito
  • Henyun Shi
  • Hirohiko Shibayama
  • Daisuke Motooka
  • Yuichi Kitai
  • Ryuta Muromoto
  • Jun-Ichi Kashiwakura
  • Kodai Saitoh
  • Daisuke Okuzaki
  • Tadashi Matsuda
  • Yuzuru Kanakura
  • Haematologica.2020 Jan;haematol.2019.225573. doi: 10.3324/haematol.2019.225573.Epub 2020-01-23.

COVID-19入院患者の肺高血圧と右室病変

Pulmonary hypertension and right ventricular involvement in hospitalised patients with COVID-19.
  • Matteo Pagnesi
  • Luca Baldetti
  • Alessandro Beneduce
  • Francesco Calvo
  • Mario Gramegna
  • Vittorio Pazzanese
  • Giacomo Ingallina
  • Antonio Napolano
  • Renato Finazzi
  • Annalisa Ruggeri
  • Silvia Ajello
  • Giulio Melisurgo
  • Paolo Guido Camici
  • Paolo Scarpellini
  • Moreno Tresoldi
  • Giovanni Landoni
  • Fabio Ciceri
  • Anna Mara Scandroglio
  • Eustachio Agricola
  • Alberto Maria Cappelletti
  • Heart.2020 Jul;heartjnl-2020-317355. doi: 10.1136/heartjnl-2020-317355.Epub 2020-07-16.

サウジアラビア王国の女子大生の体重と摂食態度の研究。異なる体重評価方法間の比較

Study of bodyweight and eating attitude among female university members in the Kingdom of Saudi Arabia: A comparison between different methods of weight assessment.
  • Rania Naguib
  • Marwa M R Tawfik
  • Sukainah A Alsubaiei
  • Altaf M Almoallem
  • Dana M Alajlouni
  • Tahani A Alruwaili
  • Wd S Sendy
  • Zainab Al Habib
  • J Family Med Prim Care.2020 Apr;9(4):2071-2078. JFMPC-9-2071. doi: 10.4103/jfmpc.jfmpc_1058_19.Epub 2020-04-30.

光学的に純粋なL-乳酸およびD-乳酸の新規生産者としての代謝工学的に設計されたLactobacillus gasseri JCM 1131

Metabolically engineered Lactobacillus gasseri JCM 1131 as a novel producer of optically pure L- and D-lactate.
  • Bojan Žunar
  • Antonija Trontel
  • Marina Svetec Miklenić
  • Juliana Lana Prah
  • Anamarija Štafa
  • Nenad Marđetko
  • Mario Novak
  • Božidar Šantek
  • Ivan Krešimir Svetec
  • World J. Microbiol. Biotechnol..2020 Jul;36(8):111. 10.1007/s11274-020-02887-2. doi: 10.1007/s11274-020-02887-2.Epub 2020-07-13.

マラソンに向かう途中で-子どもと若者のマスランニングイベント参加へのモチベーション.ポズナンハーフマラソンパイロット調査の結果

On the Way to the Marathon-Motivation for Participating in Mass Running Events Among Children and Adolescents: Results of the Poznan Half Marathon Pilot Study.
  • Ewa Malchrowicz-Mośko
  • Arkaitz Castañeda-Babarro
  • Patxi León Guereño
  • Int J Environ Res Public Health.2020 Jul;17(14). E5098. doi: 10.3390/ijerph17145098.Epub 2020-07-15.

嫌気性細菌に対する抗菌作用を有するハイドロキシアパタイトをベースとしたバイオナノコンポジットの調製と予備評価

Preparation and preliminary evaluation of bio-nanocomposites based on hydroxyapatites with antibacterial properties against anaerobic bacteria.
  • Katarzyna Zawisza
  • Paulina Sobierajska
  • Nicole Nowak
  • Anna Kedziora
  • Kamila Korzekwa
  • Blazej Pozniak
  • Marta Tikhomirov
  • Julia Miller
  • Lucyna Mrowczynska
  • Rafal J Wiglusz
  • Mater Sci Eng C Mater Biol Appl.2020 Jan;106:110295. S0928-4931(18)32616-X. doi: 10.1016/j.msec.2019.110295.Epub 2019-10-10.

血液学的悪性腫瘍患者,高用量化学療法および自己造血幹細胞移植(自己造血幹細胞移植)を受けた患者における補体活性化コレクトインおよび関連セリンプロテアーゼの役割について

The Role of Complement Activating Collectins and Associated Serine Proteases in Patients With Hematological Malignancies, Receiving High-Dose Chemotherapy, and Autologous Hematopoietic Stem Cell Transplantations (Auto-HSCT).
  • Anna S Świerzko
  • Mateusz Michalski
  • Anna Sokołowska
  • Mateusz Nowicki
  • Łukasz Eppa
  • Agnieszka Szala-Poździej
  • Iwona Mitrus
  • Anna Szmigielska-Kapłon
  • Małgorzata Sobczyk-Kruszelnicka
  • Katarzyna Michalak
  • Aleksandra Gołos
  • Agnieszka Wierzbowska
  • Sebastian Giebel
  • Krzysztof Jamroziak
  • Marek L Kowalski
  • Olga Brzezińska
  • Steffen Thiel
  • Jens C Jensenius
  • Katarzyna Kasperkiewicz
  • Maciej Cedzyński
  • Front Immunol.2018;9:2153. doi: 10.3389/fimmu.2018.02153.Epub 2018-09-20.

診断から2回目の治療までの時間は、進行期の濾胞性リンパ腫患者における全生存期間の有望な代替指標である

Time from diagnosis to 2nd treatment is a promising surrogate for overall survival in patients with advanced stage follicular lymphoma.
  • Jacob D Soumerai
  • Andy Ni
  • Anna Alperovich
  • Connie Batlevi
  • Kurt S Bantilan
  • Thais Fischer
  • Amanda R Copeland
  • Katy Smith
  • Zhitao Ying
  • Anas Younes
  • Andrew D Zelenetz
  • Leuk. Lymphoma.2020 Jul;:1-8. doi: 10.1080/10428194.2020.1791850.Epub 2020-07-15.

上腕二頭筋遠位部断裂に対する縫合糸アンカー再挿入術:断裂した腱の組織学的解析と短期・長期フォローアップにおける臨床結果

Suture anchor reinsertions of distal biceps rupture: a histological analysis of torn tendon and clinical results at short- and long-term follow up.
  • Pierfrancesco Luciani
  • Luca Farinelli
  • Elisa Senigagliesi
  • Nicola Setaro
  • Sandra Manzotti
  • Antonio Gigante
  • J Shoulder Elbow Surg.2020 Jul;S1058-2746(20)30543-7. doi: 10.1016/j.jse.2020.06.025.Epub 2020-07-07.

フィブリノゲンベンゾチアゾールの薬物相互作用の基礎的なメカニズムを計算と実験的アプローチを用いてマッピングする

Mapping the underlying mechanisms of fibrinogen benzothiazole drug interactions using computational and experimental approaches.
  • Michael González-Durruthy
  • Gustavo Scanavachi
  • Ramón Rial
  • Zhen Liu
  • M Natália D S Cordeiro
  • Rosangela Itri
  • Juan M Ruso
  • Int. J. Biol. Macromol..2020 Jul;163:730-744. S0141-8130(20)33790-9. doi: 10.1016/j.ijbiomac.2020.07.044.Epub 2020-07-09.

Baicaleinは、内皮一酸化窒素合成酵素の機能障害を改善し、酸化ストレスと線維化を抑制することで、ストレプトゾトシン誘発性I型糖尿病に伴う勃起障害を緩和する

Baicalein Alleviates Erectile Dysfunction Associated With Streptozotocin-Induced Type I Diabetes by Ameliorating Endothelial Nitric Oxide Synthase Dysfunction, Inhibiting Oxidative Stress and Fibrosis.
  • Yinwei Chen
  • Bingyan Zhou
  • Zhe Yu
  • Penghui Yuan
  • Taotao Sun
  • Jianan Gong
  • Yan Zhang
  • Tao Wang
  • Shaogang Wang
  • Kang Liu
  • JiHong Liu
  • J Sex Med.2020 Jun;S1743-6095(20)30607-X. doi: 10.1016/j.jsxm.2020.04.390.Epub 2020-06-22.

小児肥大型心筋症における突然死のリスク予測モデルの開発(HCMリスクキッズ)

Development of a Novel Risk Prediction Model for Sudden Cardiac Death in Childhood Hypertrophic Cardiomyopathy (HCM Risk-Kids).
  • Gabrielle Norrish
  • Tao Ding
  • Ella Field
  • Lidia Ziólkowska
  • Iacopo Olivotto
  • Giuseppe Limongelli
  • Aristides Anastasakis
  • Robert Weintraub
  • Elena Biagini
  • Luca Ragni
  • Terence Prendiville
  • Sophie Duignan
  • Karen McLeod
  • Maria Ilina
  • Adrián Fernández
  • Regina Bökenkamp
  • Anwar Baban
  • Peter Kubuš
  • Piers E F Daubeney
  • Georgia Sarquella-Brugada
  • Sergi Cesar
  • Chiara Marrone
  • Vinay Bhole
  • Constancio Medrano
  • Orhan Uzun
  • Elspeth Brown
  • Ferran Gran
  • Francisco J Castro
  • Graham Stuart
  • Gabriele Vignati
  • Roberto Barriales-Villa
  • Luis G Guereta
  • Satish Adwani
  • Katie Linter
  • Tara Bharucha
  • Pablo Garcia-Pavia
  • Torsten B Rasmussen
  • Margherita M Calcagnino
  • Caroline B Jones
  • Hans De Wilde
  • J Toru-Kubo
  • Tiziana Felice
  • Jens Mogensen
  • Sujeev Mathur
  • Zdenka Reinhardt
  • Constantinos O'Mahony
  • Perry M Elliott
  • Rumana Z Omar
  • Juan P Kaski
  • JAMA Cardiol.2019 09;4(9):918-927. 2747608. doi: 10.1001/jamacardio.2019.2861.

金属(ロイド)で汚染された土壌に対するフォルソミアカンジダとエンキトラエウスクリプティカスの忌避行動に及ぼす気候条件の影響

Effects of climate conditions on the avoidance behavior of Folsomia candida and Enchytraeus crypticus towards metal(loid)-contaminated soils.
  • Catarina Malheiro
  • Diogo N Cardoso
  • Susana Loureiro
  • M Nazaret González-Alcaraz
  • Sci. Total Environ..2020 Jun;741:140368. S0048-9697(20)33890-0. doi: 10.1016/j.scitotenv.2020.140368.Epub 2020-06-20.

肺胞毛細血管異形成を有する2人のポーランドの新生児における遺伝子型とフェノタイプの相関

Genotype-phenotype correlation in two Polish neonates with alveolar capillary dysplasia.
  • Zuzanna Kozłowska
  • Zuzanna Owsiańska
  • Joanna P Wroblewska
  • Apolonia Kałużna
  • Andrzej Marszałek
  • Yogen Singh
  • Bartłomiej Mroziński
  • Qian Liu
  • Justyna A Karolak
  • Paweł Stankiewicz
  • Gail Deutsch
  • Marta Szymankiewicz-Bręborowicz
  • Tomasz Szczapa
  • BMC Pediatr.2020 Jun;20(1):320. 10.1186/s12887-020-02200-y. doi: 10.1186/s12887-020-02200-y.Epub 2020-06-29.

液体クロマトグラフィー・タンデム質量分析法による全血溶解液中のアザチオプリン代謝物の高感度かつ迅速な定量

Highly sensitive and rapid determination of azathioprine metabolites in whole blood lysate by liquid chromatography-tandem mass spectrometry.
  • Qiang Miao
  • Yang-Juan Bai
  • Jun-Long Zhang
  • Yi Li
  • Zhen-Zhen Su
  • Lin Yan
  • Lan-Lan Wang
  • Yuan-Gao Zou
  • J. Chromatogr. B Analyt. Technol. Biomed. Life Sci..2020 Jan;1136:121802. S1570-0232(19)31085-2. doi: 10.1016/j.jchromb.2019.121802.Epub 2019-09-13.

コラーゲンメチオニンスルホキシドとグルクロニジン/LW-1は1型糖尿病の長期生存者における冠動脈疾患のマーカーである。ジアロン試験である

Collagen methionine sulfoxide and glucuronidine/LW-1 are markers of coronary artery disease in long-term survivors with type 1 diabetes. The Dialong study.
  • Kristine B Holte
  • Mona Svanteson
  • Kristian F Hanssen
  • Kari Anne Sveen
  • Ingebjørg Seljeflot
  • Svein Solheim
  • David R Sell
  • Vincent M Monnier
  • Tore Julsrud Berg
  • PLoS ONE.2020;15(5):e0233174. PONE-D-20-00205. doi: 10.1371/journal.pone.0233174.Epub 2020-05-13.

Cynomolgus MonkeysおよびMiceにおけるCoproporphyrin I (CPI)の吸収および処分:OATP阻害の可能性を伝えるためのCPIの使用を支持する薬物動態学的証拠

Absorption and Disposition of Coproporphyrin I (CPI) in Cynomolgus Monkeys and Mice: Pharmacokinetic Evidence to Support the Use of CPI to Inform the Potential for OATP Inhibition.
  • Xiaomei Gu
  • Lifei Wang
  • Jinping Gan
  • R Marcus Fancher
  • Yuan Tian
  • Yang Hong
  • Yurong Lai
  • Michael Sinz
  • Hong Shen
  • Drug Metab. Dispos..2020 Jun;dmd.120.090670. doi: 10.1124/dmd.120.090670.Epub 2020-06-01.

ギリシャの第三次医療病院でVIM-4産生プロテウス・ミラビリスによるクローン感染が発生した

Clonal outbreak caused by VIM-4-producing Proteus mirabilis in a Greek tertiary-care hospital.
  • Efthymia Protonotariou
  • Aggeliki Poulou
  • Lida Politi
  • Georgios Meletis
  • Fani Chatzopoulou
  • Antigoni Malousi
  • Symeon Metallidis
  • Athanasios Tsakris
  • Lemonia Skoura
  • Int. J. Antimicrob. Agents.2020 Jun;:106060. S0924-8579(20)30230-2. doi: 10.1016/j.ijantimicag.2020.106060.Epub 2020-06-20.

フェンタニルはモルヒネではなく、非オピオイド系組換えヒト神経伝達物質受容体およびトランスポーターと相互作用する

Fentanyl but not Morphine Interacts with Non-Opioid Recombinant Human Neurotransmitter Receptors and Transporters.
  • Randy Torralva
  • Amy J Eshleman
  • Tracy L Swanson
  • Jennifer L Schmachtenberg
  • William E Schutzer
  • Shelley H Bloom
  • Katherine M Wolfrum
  • John F Reed
  • Aaron Janowsky
  • J. Pharmacol. Exp. Ther..2020 Jun;jpet.120.265561. doi: 10.1124/jpet.120.265561.Epub 2020-06-08.

インド・コルカタ市の下痢便サンプルの腸内マイクロバイオームとレジストームをメタゲノム解析したところ、微生物暗黒物質のシグネチャーを含む中核的で可変性のあるマイクロバイオータが明らかになった

Metagenomic analysis of gut microbiome and resistome of diarrheal fecal samples from Kolkata, India, reveals the core and variable microbiota including signatures of microbial dark matter.
  • Rituparna De
  • Asish Kumar Mukhopadhyay
  • Shanta Dutta
  • Gut Pathog.2020;12:32. 371. doi: 10.1186/s13099-020-00371-8.Epub 2020-07-07.

ラットの腸間膜動脈におけるインスリン介在性血管拡張に対するグルココルチコイドの高用量投与の効果

Effects of high doses of glucocorticoids on insulin-mediated vasodilation in the mesenteric artery of rats.
  • João Eliakim Dos S Araujo
  • Rodrigo Miguel-Dos-Santos
  • Fabrício N Macedo
  • Patrícia S Cunha
  • Milene Tavares Fontes
  • Gilson Masahiro Murata
  • Sandra Lauton-Santos
  • Valter J Santana-Filho
  • Ana Mara de O Silva
  • Angelo Roberto Antoniolli
  • Rui Curi
  • Jullyana de S S Quintans
  • Rosana de S S Barreto
  • Marcio R V Santos
  • Lucindo J Quintans-Junior
  • André S Barreto
  • PLoS ONE.2020;15(3):e0230514. PONE-D-19-25453. doi: 10.1371/journal.pone.0230514.Epub 2020-03-18.

インドのオーディシャ州、アッサム州、マニプール州の豚集団における日本脳炎ウイルスの分子疫学

Molecular epidemiology of Japanese encephalitis virus in pig population of Odisha, Assam and Manipur states of India.
  • Ankita Datey
  • Leichombam Mohindro Singh
  • Uttam Rajkhowa
  • Birendra Kumar Prusty
  • Tanuja Saswat
  • Prabhudutta Mamidi
  • Luit Moni Barkalita
  • Rupam Dutta
  • K Chandradev Sharma
  • Dinabandhu Sahoo
  • Probodh Borah
  • Sarangthem Indira Devi
  • Soma Chattopadhyay
  • Infect. Genet. Evol..2020 Sep;83:104325. S1567-1348(20)30156-8. doi: 10.1016/j.meegid.2020.104325.Epub 2020-04-20.

免疫チェックポイント阻害薬誘発性筋骨格系症状。多施設共同プロスペクティブ研究

Immune checkpoint inhibitor-induced musculoskeletal manifestations. A multicentre prospective study.
  • Dimitrios Daoussis
  • Konstantinos Melissaropoulos
  • Theodoros Dimitroulas
  • Haralambos Andreadis
  • Athina Christopoulou
  • George Douganiotis
  • Thomas Makatsoris
  • Angelos Koutras
  • Panagiotis Georgiou
  • Haralabos Kalofonos
  • Mediterr J Rheumatol.2020 Jun;31(2):239-241. mjr-31-2-239. doi: 10.31138/mjr.31.2.239.Epub 2020-04-24.

光活性フタロシアニン誘導体をベースとした抗菌剤の毒性試験

Toxicological testing of a photoactive phthalocyanine-based antimicrobial substance.
  • Kristina Kejlová
  • Hana Bendová
  • Jan Chrz
  • Markéta Dvořáková
  • Lada Svobodová
  • Alena Vlková
  • Lubomír Kubáč
  • Radka Kořínková
  • Jiří Černý
  • Danuše Očadlíková
  • Marian Rucki
  • Tuula Heinonen
  • Dagmar Jírová
  • Silvia Letašiová
  • Helena Kandarova
  • Hana Kolářová
  • Regul. Toxicol. Pharmacol..2020 May;115:104685. S0273-2300(20)30111-2. doi: 10.1016/j.yrtph.2020.104685.Epub 2020-05-23.

FGF-1は膵β細胞の機能・代謝を調節する。膵臓の機能・代謝を調節するFGF-1のin vitro試験

FGF-1 modulates pancreatic β-cell functions/metabolism: An in vitro study.
  • Pawel A Kolodziejski
  • Maciej Sassek
  • Jakub Bien
  • Natalia Leciejewska
  • Dawid Szczepankiewicz
  • Beata Szczepaniak
  • Malgorzata Wojciechowska
  • Leszek Nogowski
  • Krzysztof W Nowak
  • Mathias Z Strowski
  • Ewa Pruszynska-Oszmalek
  • Gen. Comp. Endocrinol..2020 Aug;294:113498. S0016-6480(20)30163-5. doi: 10.1016/j.ygcen.2020.113498.Epub 2020-04-29.

キサンテジオン(およびその合成に関与する中間体)は、マウス新生児モデルにおける中枢神経系へのジカウイルス移行を阻害する

Xanthenedione (and intermediates involved in their synthesis) inhibit Zika virus migration to the central nervous system in murine neonatal models.
  • Ítalo Esposti Poly da Silva
  • Milene Lopes da Silva
  • Roberto Sousa Dias
  • Edjon Gonçalves Santos
  • Maria Cecília Brangioni de Paula
  • André Silva de Oliveira
  • Ana Flávia Costa da Silveira Oliveira
  • Fabrício Marques de Oliveira
  • Cynthia Canedo da Silva
  • Róbson Ricardo Teixeira
  • Sérgio Oliveira de Paula
  • Microbes Infect..2020 Apr;S1286-4579(20)30074-5. doi: 10.1016/j.micinf.2020.04.007.Epub 2020-04-27.

多能性幹細胞からの骨形成前駆細胞の系統特異的分化により、神経堤由来の骨形成前駆細胞におけるFGF1-RUNX2の関連性が明らかになった

Lineage-specific differentiation of osteogenic progenitors from pluripotent stem cells reveals the FGF1-RUNX2 association in neural crest-derived osteoprogenitors.
  • Fahad Kidwai
  • Byron W H Mui
  • Deepika Arora
  • Kulsum Iqbal
  • Madison Hockaday
  • Luis Fernandez de Castro Diaz
  • Natasha Cherman
  • Daniel Martin
  • Vamsee D Myneni
  • Moaz Ahmad
  • Katarzyna Futrega
  • Sania Ali
  • Randall K Merling
  • Dan S Kaufman
  • Janice Lee
  • Pamela G Robey
  • Stem Cells.2020 May;doi: 10.1002/stem.3206.Epub 2020-05-22.

鈍的外傷後の表在性大腿動脈枝からの出血に対して、n-ブチルシアノアクリレートを用いた超選択的塞栓術が成功した。3例の症例報告

Successful superselective embolization with n-butyl cyanoacrylate for hemorrhage from superficial femoral artery branches following blunt trauma: Three case reports.
  • Chang Hoon Oh
  • Yook Kim
  • Jung Hwan Lee
  • Hong Rye Kim
  • Seung Je Go
  • Medicine (Baltimore).2020 Jul;99(27):e20467. 00005792-202007020-00009. doi: 10.1097/MD.0000000000020467.

SARS-CoV-2感染症の入院患者(COVID-19)を対象に、標準治療と比較してロピナビル/リトナビルおよび/またはヒドロキシクロロキンによる治療を行った場合の臨床転帰を評価するためのオーストラレーシアCOVID-19試験(ASCOT)。無作為化比較試験の試験計画書の構造化された要約

The Australasian COVID-19 Trial (ASCOT) to assess clinical outcomes in hospitalised patients with SARS-CoV-2 infection (COVID-19) treated with lopinavir/ritonavir and/or hydroxychloroquine compared to standard of care: A structured summary of a study protocol for a randomised controlled trial.
  • Justin T Denholm
  • Joshua Davis
  • David Paterson
  • Jason Roberts
  • Susan Morpeth
  • Thomas Snelling
  • Dominica Zentner
  • Megan Rees
  • Matthew O'Sullivan
  • David Price
  • Asha Bowen
  • Steven Y C Tong
  • Trials.2020 Jul;21(1):646. 10.1186/s13063-020-04576-9. doi: 10.1186/s13063-020-04576-9.Epub 2020-07-14.

口蓋と上顎歯列弓の特徴は統合失調症の男性の解剖学的マーカーになり得るか?ケースコントロール研究。口蓋は統合失調症のマーカーになりうるか?

The characteristics of palate and upper dental arch can be an anatomical marker for men with schizophrenia? Case-control study: Palate can be a marker for schizophrenia?
  • Rafael Zancan Mobile
  • Ana Clelia Roussenq
  • Melissa Rodrigues de Araujo
  • Ricardo Sbalqueiro
  • José Vinícius Bolognesi Maciel
  • Antonio Adilson Soares de Lima
  • Spec Care Dentist.2020 Jul;doi: 10.1111/scd.12488.Epub 2020-07-03.

高血圧性心疾患における左室捻転-解撚障害と血管機能障害,神経体液性活性化,運動能力低下との関連

Association of impaired left ventricular twisting-untwisting with vascular dysfunction, neurohumoral activation and impaired exercise capacity in hypertensive heart disease.
  • Ignatios Ikonomidis
  • Stavros Tzortzis
  • Helen Triantafyllidi
  • John Parissis
  • Costas Papadopoulos
  • Kyriaki Venetsanou
  • Paraskevi Trivilou
  • Ioannis Paraskevaidis
  • John Lekakis
  • Eur. J. Heart Fail..2015 Dec;17(12):1240-51. doi: 10.1002/ejhf.403.Epub 2015-10-07.

人工呼吸器関連肺炎の原因となる病原体と抗生物質に対する耐性を迅速に同定するためのポイント・オブ・ケア・マルチプレックスPCRの有用性:観察研究

Usefulness of point-of-care multiplex PCR to rapidly identify pathogens responsible for ventilator-associated pneumonia and their resistance to antibiotics: an observational study.
  • Charles-Edouard Luyt
  • Guillaume Hékimian
  • Isabelle Bonnet
  • Nicolas Bréchot
  • Matthieu Schmidt
  • Jérôme Robert
  • Alain Combes
  • Alexandra Aubry
  • Crit Care.2020 06;24(1):378. 10.1186/s13054-020-03102-2. doi: 10.1186/s13054-020-03102-2.Epub 2020-06-26.

プロテオミクス解析により、Lactuca sativa cv. Salinas の主要な代謝経路に関与するタンパク質が Lactuca serriola Accession US96UC23 よりも豊富であることが示された

Proteomics Analysis Indicates Greater Abundance of Proteins Involved in Major Metabolic Pathways in Lactuca sativa cv. Salinas than Lactuca serriola Accession US96UC23.
  • Neil D Adhikari
  • Renée L Eriksen
  • Ainong Shi
  • Beiquan Mou
  • Proteomics.2020 Jul;:e1900420. doi: 10.1002/pmic.201900420.Epub 2020-07-16.

化学療法または放射線誘発性早発卵巣不全を有する青年期および若年女性におけるホルモン補充療法。実用的な推奨事項

Hormonal replacement therapy in adolescents and young women with chemo- or radio-induced premature ovarian insufficiency: Practical recommendations.
  • A Cattoni
  • F Parissone
  • I Porcari
  • S Molinari
  • N Masera
  • M Franchi
  • S Cesaro
  • R Gaudino
  • P Passoni
  • A Balduzzi
  • Blood Rev..2020 Jul;:100730. S0268-960X(20)30080-1. doi: 10.1016/j.blre.2020.100730.Epub 2020-07-04.

耳介類肺虫の糞便および鼻腔スワブ検出のための新しい定量的リアルタイムPCR診断アッセイ、

A novel quantitative real-time PCR diagnostic assay for fecal and nasal swab detection of an otariid lungworm, .
  • Kalani M Williams
  • M K Fessler
  • R A Bloomfield
  • William D Sandke
  • Clara R Malekshahi
  • Caroline D Keroack
  • Pádraig J Duignan
  • Samantha D Torquato
  • Steven A Williams
  • Int J Parasitol Parasites Wildl.2020 Aug;12:85-92. S2213-2244(20)30043-2. doi: 10.1016/j.ijppaw.2020.04.012.Epub 2020-05-18.

顎関節骨コンポーネントの想像力学的三次元研究-矢状骨格関係、性別、年齢に応じた顎関節骨コンポーネントの研究

Imaginology Tridimensional Study of Temporomandibular Joint Osseous Components According to Sagittal Skeletal Relationship, Sex, and Age.
  • Fernanda Lobo
  • Elen de Souza Tolentino
  • Lilian Cristina Vessoni Iwaki
  • Leticia Ângelo Walewski
  • Wilton Mitsunari Takeshita
  • Mariliani Chicarelli
  • J Craniofac Surg.2019 Jul;30(5):1462-1465. 00001665-201907000-00036. doi: 10.1097/SCS.0000000000005467.

エンジェルマン症候群の非定型を呈する患者のゲノムシークエンシングにより同定されたUBE3Aの新規イントロニックバリアント

A novel intronic variant in UBE3A identified by genome sequencing in a patient with an atypical presentation of Angelman syndrome.
  • Meredith Curtis
  • Danielle Baribeau
  • Susan Walker
  • Melissa Carter
  • Gregory Costain
  • Sylvia Lamoureux
  • Eriskay Liston
  • Christian R Marshall
  • Miriam S Reuter
  • Meaghan Snell
  • Jane Summers
  • Jacob Vorstman
  • Rebekah K Jobling
  • Am. J. Med. Genet. A.2020 Jul;doi: 10.1002/ajmg.a.61740.Epub 2020-07-11.

HULCの過剰発現は、NLRP3/Caspase-1/IL-1βシグナル伝達経路阻害を介してmiR-377-5pを標的とした低酸素/再酸素化心筋細胞のアポトーシスを抑制し、心筋虚血/再灌流障害を抑制することを明らかにした

Overexpression of lncRNA HULC Attenuates Myocardial Ischemia/reperfusion Injury in Rat Models and Apoptosis of Hypoxia/reoxygenation Cardiomyocytes via Targeting miR-377-5p through NLRP3/Caspase‑1/IL‑1β Signaling Pathway Inhibition.
  • Huiqing Liang
  • Fangjiang Li
  • Huixian Li
  • Rui Wang
  • Meiling Du
  • Immunol. Invest..2020 Jul;:1-14. doi: 10.1080/08820139.2020.1791178.Epub 2020-07-17.