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日本語AIでPubMedを検索

日本語AIでPubMedを検索

PubMedの提供する医学論文データベースを日本語で検索できます。AI(Deep Learning)を活用した機械翻訳エンジンにより、精度高く日本語へ翻訳された論文をご参照いただけます。

みんなが読んでいる論文

ケーブル産業のためのコーティング材料としての緑の高度に粘土充填ポリエチレン複合材料-高分子材料における非有機フィル化天然モンモリロナイトの新しい応用ルート

Green Highly Clay-Filled Polyethylene Composites as Coating Materials for Cable Industry-A New Application Route of Non-Organophilised Natural Montmorillonites in Polymeric Materials.
  • Stanisław Wysocki
  • Krzysztof Kowalczyk
  • Sandra Paszkiewicz
  • Paweł Figiel
  • Elżbieta Piesowicz
  • Polymers (Basel).2020 Jun;12(6). E1399. doi: 10.3390/polym12061399.Epub 2020-06-22.

治療用PSD-95阻害剤と細胞貫通ペプチドTatとの共役は、血液脳関門への付着、取り込み、浸透に影響を与える

Conjugation of Therapeutic PSD-95 Inhibitors to the Cell-Penetrating Peptide Tat Affects Blood-Brain Barrier Adherence, Uptake, and Permeation.
  • Mie Kristensen
  • Krzysztof Kucharz
  • Eduardo Felipe Alves Fernandes
  • Kristian Strømgaard
  • Morten Schallburg Nielsen
  • Hans Christian Cederberg Helms
  • Anders Bach
  • Malte Ulrikkaholm Tofte-Hansen
  • Blanca Irene Aldana Garcia
  • Martin Lauritzen
  • Birger Brodin
  • Pharmaceutics.2020 Jul;12(7). E661. doi: 10.3390/pharmaceutics12070661.Epub 2020-07-14.

慢性頭痛を持つ青年とその保護者を対象とした1日グループ介入「偏頭痛キャンプ」での患者体験の改善

Improving the Patient Experience With Migraine Camp, a One-Day Group Intervention for Adolescents With Chronic Headache and Their Parents.
  • Amanda L Hall
  • Dina Karvounides
  • Amy A Gelfand
  • Haley Mankin
  • Shirley Kessel
  • Janet Corroo
  • Carrie P Malavolta
  • Tara Pezzuto
  • Madeline Chadehumbe
  • Christina L Szperka
  • Headache.2019 09;59(8):1392-1400. doi: 10.1111/head.13570.Epub 2019-06-05.

遺伝的機能障害の根底にある広範な大動脈・頸動脈・腹部解剖を有する患者における欠失の分子的影響の検討

Examination of Molecular Effects of Deletion in a Patient with Extensive Aortic, Carotid, and Abdominal Dissections That Underlie the Genetic Dysfunction.
  • Sarah K Macklin
  • Katelyn A Bruno
  • Charitha Vadlamudi
  • Haytham Helmi
  • Ayesha Samreen
  • Ahmed N Mohammad
  • Stepahnie Hines
  • Paldeep S Atwal
  • Thomas R Caulfield
  • Case Rep Med.2020;2020:5108052. doi: 10.1155/2020/5108052.Epub 2020-06-19.

TLR3および7/8アゴニストベースのDC成熟化カクテルにおけるプロスタグランジンEは、成熟したサイトカイン産生性の遊走性DCを産生するが、CD8 T細胞への抗原クロスプレゼンテーションを損なう

Prostaglandin E in a TLR3- and 7/8-agonist-based DC maturation cocktail generates mature, cytokine-producing, migratory DCs but impairs antigen cross-presentation to CD8 T cells.
  • Philipp Gierlich
  • Veronika Lex
  • Antje Technau
  • Anne Keupp
  • Lorenz Morper
  • Amelie Glunz
  • Hanno Sennholz
  • Johannes Rachor
  • Sascha Sauer
  • Ana Marcu
  • Götz Ulrich Grigoleit
  • Matthias Wölfl
  • Paul G Schlegel
  • Matthias Eyrich
  • Cancer Immunol. Immunother..2020 Jun;69(6):1029-1042. 10.1007/s00262-019-02470-1. doi: 10.1007/s00262-019-02470-1.Epub 2020-02-25.

ドコサヘキサエン酸は、肺動脈平滑筋細胞のmicroRNA-16をアップレギュレートすることでCa流入を抑制し、CaSRをダウンレギュレートする

Docosahexaenoic acid inhibits Ca influx and downregulates CaSR by upregulating microRNA-16 in pulmonary artery smooth muscle cells.
  • Jin-Jun Liu
  • Ming-Ming Tang
  • Ming-Li Zhu
  • Cai-Xia Xie
  • Pin-Fang Kang
  • Xuan Ling
  • Heng Zhang
  • Xiao-Jing Wang
  • Bi Tang
  • J. Biochem. Mol. Toxicol..2020 Jul;:e22573. doi: 10.1002/jbt.22573.Epub 2020-07-13.

スフィンゴシンキナーゼ1/スフィンゴシン1-リン酸塩/スフィンゴシン1-リン酸塩受容体1経路。ゲニポシドによる血管新生抑制の新規ターゲット

Sphingosine kinase 1/sphingosine 1-phosphate/sphingosine 1-phosphate receptor 1 pathway: A novel target of geniposide to inhibit angiogenesis.
  • Minghui Sun
  • Ran Deng
  • Yan Wang
  • Hong Wu
  • Zhengrong Zhang
  • Yanhong Bu
  • Heng Zhang
  • Life Sci..2020 Jun;256:117988. S0024-3205(20)30738-4. doi: 10.1016/j.lfs.2020.117988.Epub 2020-06-20.

全身性疾患の歯周病症状と発生・後天性疾患。2017年歯周病およびインプラント周囲疾患・状態の分類に関する世界ワークショップのワークグループ3のコンセンサス報告書

Periodontal manifestations of systemic diseases and developmental and acquired conditions: Consensus report of workgroup 3 of the 2017 World Workshop on the Classification of Periodontal and Peri-Implant Diseases and Conditions.
  • Søren Jepsen
  • Jack G Caton
  • Jasim M Albandar
  • Nabil F Bissada
  • Philippe Bouchard
  • Pierpaolo Cortellini
  • Korkud Demirel
  • Massimo de Sanctis
  • Carlo Ercoli
  • Jingyuan Fan
  • Nicolaas C Geurs
  • Francis J Hughes
  • Lijian Jin
  • Alpdogan Kantarci
  • Evanthia Lalla
  • Phoebus N Madianos
  • Debora Matthews
  • Michael K McGuire
  • Michael P Mills
  • Philip M Preshaw
  • Mark A Reynolds
  • Anton Sculean
  • Cristiano Susin
  • Nicola X West
  • Kazuhisa Yamazaki
  • J. Periodontol..2018 06;89 Suppl 1:S237-S248. doi: 10.1002/JPER.17-0733.

プロトポルフィリンIX上で図示された、非指数的遅延蛍光および燐光減衰分析のための一般的なフレームワーク

A general framework for non-exponential delayed fluorescence and phosphorescence decay analysis, illustrated on Protoporphyrin IX.
  • Gauthier Croizat
  • Aurélien Gregor
  • Emmanuel Gerelli
  • Jaroslava Joniova
  • Marek Scholz
  • Georges Wagnières
  • J. Photochem. Photobiol. B, Biol..2020 Apr;209:111887. S1011-1344(20)30336-5. doi: 10.1016/j.jphotobiol.2020.111887.Epub 2020-04-30.

マルチエコーを用いた拡散強調MRIにおける感度と信号対雑音比の向上

Increased Sensitivity and Signal-to-Noise Ratio in Diffusion-Weighted MRI using Multi-Echo Acquisitions.
  • Cornelius Eichner
  • Michael Paquette
  • Toralf Mildner
  • Torsten Schlumm
  • Kamilla Pleh
  • Liran Samuni
  • Catherine Crockford
  • Roman M Wittig
  • Carsten Jäger
  • Harald E Möller
  • Angela D Friederici
  • Alfred Anwander
  • Neuroimage.2020 Jul;:117172. S1053-8119(20)30658-3. doi: 10.1016/j.neuroimage.2020.117172.Epub 2020-07-15.

溶解性と腸管透過性を改善するためのマイクロエマルジョン中の未熟オリーブ(L. )からのフェノールリッチ抽出物の製剤化

Formulation of a Phenol-Rich Extract from Unripe Olives ( L.) in Microemulsion to Improve Its Solubility and Intestinal Permeability.
  • Lorenzo Cecchi
  • Vieri Piazzini
  • Mario D'Ambrosio
  • Cristina Luceri
  • Federica Rocco
  • Marzia Innocenti
  • Giulia Vanti
  • Nadia Mulinacci
  • Maria Camilla Bergonzi
  • Molecules.2020 Jul;25(14). E3198. doi: 10.3390/molecules25143198.Epub 2020-07-13.

半閉鎖された亜熱帯の湾内で、環境DNA検出の追跡により、ブラックチップ・シャーク(Carcharhinus limbatus)の季節的な発生が確認された

Environmental DNA detection tracks established seasonal occurrence of blacktip sharks (Carcharhinus limbatus) in a semi-enclosed subtropical bay.
  • Bautisse D Postaire
  • Judith Bakker
  • Jayne Gardiner
  • Tonya R Wiley
  • Demian D Chapman
  • Sci Rep.2020 Jul;10(1):11847. 10.1038/s41598-020-68843-0. doi: 10.1038/s41598-020-68843-0.Epub 2020-07-16.

Nulliparous 思春期の青年および若い女性におけるレボノルゲストレル放出型子宮内装置挿入の12時間前の膣ディノプロストンの自己投与の利点。無作為化対照試験

Benefits of Self-administered Vaginal Dinoprostone 12 Hours before Levonorgestrel-releasing Intrauterine Device Insertion in Nulliparous Adolescents and Young Women: A Randomized Controlled Trial.
  • Ahmed Samy
  • Ahmed Said Ali
  • Dina Latif
  • Fatma Faisal Darweesh
  • Nevein Kamal Ghamry
  • Ahmed A Metwally
  • J Pediatr Adolesc Gynecol.2020 Feb;S1083-3188(20)30163-7. doi: 10.1016/j.jpag.2020.02.010.Epub 2020-02-28.

退役軍人健康管理局(Veterans Health Administration)で前立腺がんと診断された患者の平均余命推定値

Life expectancy estimates for patients diagnosed with prostate cancer in the Veterans Health Administration.
  • Ericka M Sohlberg
  • I-Chun Thomas
  • Jaden Yang
  • Kristopher Kapphahn
  • Timothy J Daskivich
  • Ted A Skolarus
  • Jeremy B Shelton
  • Danil V Makarov
  • Jonathan Bergman
  • Christine Ko Bang
  • Mary K Goldstein
  • Todd H Wagner
  • James D Brooks
  • Manisha Desai
  • John T Leppert
  • Urol. Oncol..2020 Jul;S1078-1439(20)30219-2. doi: 10.1016/j.urolonc.2020.05.015.Epub 2020-07-13.

慢性疾患における注射剤治療の提供と管理における促進要因と障壁に関する統合的レビュー。ACNAPプロジェクト「心血管疾患患者における注射薬」の一部

An integrative review on facilitators and barriers in delivering and managing injectable therapies in chronic conditions: A part of the ACNAP project 'injectable medicines among patients with cardiovascular conditions'.
  • Ekaterini Lambrinou
  • Martha Kyriakou
  • Ioanna Lakatamitou
  • Neil Angus
  • Rani Khatib
  • Ercole Vellone
  • Abigail Barrowcliff
  • Tina Birgitte Hansen
  • Geraldine A Lee
  • Eur J Cardiovasc Nurs.2020 Jul;:1474515120939007. doi: 10.1177/1474515120939007.Epub 2020-07-16.

ヒトの新生児のエタノール臭に対する呼吸と感情の反応性は、妊娠中の母親の飲酒パターンに依存している

Respiratory and emotional reactivity to ethanol odor in human neonates is dependent upon maternal drinking patterns during pregnancy.
  • Florencia Anunziata
  • Ana Fabiola Macchione
  • Adriana Sofía Mitrano
  • Génesis D'aloisio
  • Mirta Elena Ferreyra
  • Ricardo David Pontoriero
  • Luis Alberto Ahumada
  • Juan Carlos Molina
  • Drug Alcohol Depend.2020 Jun;213:108100. S0376-8716(20)30265-9. doi: 10.1016/j.drugalcdep.2020.108100.Epub 2020-06-11.

Bowman-Birk阻害剤とその由来ペプチドの血圧低下効果

Blood pressure-lowering effects of a Bowman-Birk inhibitor and its derived peptides in normotensive and hypertensive rats.
  • Maria Alzira Garcia de Freitas
  • Nathalia Oda Amaral
  • Alice da Cunha Morales Álvares
  • Sandriele Aires de Oliveira
  • Azadeh Mehdad
  • Diego Elias Honda
  • Amanda Sá Martins Bessa
  • Marcelo Henrique Soller Ramada
  • Lara Marques Naves
  • Carolina Nobre Ribeiro Pontes
  • Carlos Henrique Castro
  • Gustavo Rodrigues Pedrino
  • Sonia Maria de Freitas
  • Sci Rep.2020 Jul;10(1):11680. 10.1038/s41598-020-66624-3. doi: 10.1038/s41598-020-66624-3.Epub 2020-07-15.

早期生活環境曝露と小児肥満。エクスポゾンワイドアプローチ

Early-Life Environmental Exposures and Childhood Obesity: An Exposome-Wide Approach.
  • Martine Vrijheid
  • Serena Fossati
  • Léa Maitre
  • Sandra Márquez
  • Theano Roumeliotaki
  • Lydiane Agier
  • Sandra Andrusaityte
  • Solène Cadiou
  • Maribel Casas
  • Montserrat de Castro
  • Audrius Dedele
  • David Donaire-Gonzalez
  • Regina Grazuleviciene
  • Line S Haug
  • Rosemary McEachan
  • Helle Margrete Meltzer
  • Eleni Papadopouplou
  • Oliver Robinson
  • Amrit K Sakhi
  • Valerie Siroux
  • Jordi Sunyer
  • Per E Schwarze
  • Ibon Tamayo-Uria
  • Jose Urquiza
  • Marina Vafeiadi
  • Antonia Valentin
  • Charline Warembourg
  • John Wright
  • Mark J Nieuwenhuijsen
  • Cathrine Thomsen
  • Xavier Basagaña
  • Rémy Slama
  • Leda Chatzi
  • Environ. Health Perspect..2020 Jun;128(6):67009. doi: 10.1289/EHP5975.Epub 2020-06-24.

色素上皮由来の新規ナチュラルキラー細胞由来因子である色素上皮由来因子は、妊娠初期に抗炎症と抗アポトーシスを介して間質細胞を保護する

Pigment epithelium-derived factor, a novel decidual natural killer cells-derived factor, protects decidual stromal cells via anti-inflammation and anti-apoptosis in early pregnancy.
  • Ji Zheng
  • Yanhong Li
  • Yifei Sang
  • Ling Xu
  • Xueling Jin
  • Yu Tao
  • Dajin Li
  • Meirong Du
  • Hum. Reprod..2020 Jul;35(7):1537-1552. 5858162. doi: 10.1093/humrep/deaa118.

EPSTI1の上昇は、原発性シェーグレン症候群患者においてNF-κBシグナルを介してB細胞の過剰活性化を促進する

Elevated EPSTI1 promote B cell hyperactivation through NF-κB signalling in patients with primary Sjögren's syndrome.
  • Jin-Lei Sun
  • Hao-Ze Zhang
  • Su-Ying Liu
  • Chao-Feng Lian
  • Zhi-Lei Chen
  • Ti-Hong Shao
  • Shuo Zhang
  • Li-Ling Zhao
  • Cheng-Mei He
  • Mu Wang
  • Wen Zhang
  • Hua Chen
  • Feng-Chun Zhang
  • Ann. Rheum. Dis..2020 04;79(4):518-524. annrheumdis-2019-216428. doi: 10.1136/annrheumdis-2019-216428.Epub 2020-02-29.

甲状腺ホルモン受容体によるtRNAメチルトランスフェラーゼ様1(Mettl1)遺伝子の直接的な活性化は、成体の腸管幹細胞の発生と変態期の増殖に関与していることを示唆している

Direct activation of tRNA methyltransferase-like 1 (Mettl1) gene by thyroid hormone receptor implicates a role in adult intestinal stem cell development and proliferation during metamorphosis.
  • Wonho Na
  • Liezhen Fu
  • Nga Luu
  • Yun-Bo Shi
  • Cell Biosci.2020;10:60. 423. doi: 10.1186/s13578-020-00423-1.Epub 2020-05-04.

カスパーゼ11はアレルギー性気道炎症を促進する

Caspase-11 promotes allergic airway inflammation.
  • Zbigniew Zasłona
  • Ewelina Flis
  • Mieszko M Wilk
  • Richard G Carroll
  • Eva M Palsson-McDermott
  • Mark M Hughes
  • Ciana Diskin
  • Kathy Banahan
  • Dylan G Ryan
  • Alexander Hooftman
  • Alicja Misiak
  • Jay Kearney
  • Gunter Lochnit
  • Wilhelm Bertrams
  • Timm Greulich
  • Bernd Schmeck
  • Oliver J McElvaney
  • Kingston H G Mills
  • Ed C Lavelle
  • Małgorzata Wygrecka
  • Emma M Creagh
  • Luke A J O'Neill
  • Nat Commun.2020 02;11(1):1055. 10.1038/s41467-020-14945-2. doi: 10.1038/s41467-020-14945-2.Epub 2020-02-26.

外傷を受けた上顎中切歯の治療と審美的管理に歯内療法とインサイド/アウトサイドブリーチング法を用いた.臨床報告

Treatment and esthetic management of traumatized maxillary central incisors with endodontic therapy and the inside/outside bleaching technique: A clinical report.
  • Michael L Myers
  • Mario F Romero
  • Lisiane F Susin
  • Courtney S Babb
  • J Prosthet Dent.2019 Oct;122(4):343-347. S0022-3913(18)31019-9. doi: 10.1016/j.prosdent.2018.10.020.Epub 2019-04-23.

心血管リスク因子は脳卒中重症度と先行認知機能障害を介して脳卒中後の急性認知に間接的に影響を与える:モデレートされた媒介分析

Cardiovascular risk factors indirectly affect acute post-stroke cognition through stroke severity and prior cognitive impairment: a moderated mediation analysis.
  • Bogna A Drozdowska
  • Emma Elliott
  • Martin Taylor-Rowan
  • Robert C Shaw
  • Gillian Cuthbertson
  • Peter Langhorne
  • Terence J Quinn
  • Alzheimers Res Ther.2020 Jul;12(1):85. 10.1186/s13195-020-00653-y. doi: 10.1186/s13195-020-00653-y.Epub 2020-07-16.

式:text参照、黒人参由来の希少なプロトパナキサトリオール型ジンセノサイド画分、Suppresses Inflammatory Gene iNOS via the Iinhibition of p-STAT-1 and NF-Formula:textB

[Formula: see text], a Rare Protopanaxatriol-Type Ginsenoside Fraction from Black Ginseng, Suppresses Inflammatory Gene iNOS via the Iinhibition of p-STAT-1 and NF-[Formula: see text]B.
  • So Yeon Jeong
  • Ji-Eun Kim
  • Gyu-Yong Song
  • Jong-Sup Bae
  • Am. J. Chin. Med..2020;48(5):1091-1102. doi: 10.1142/S0192415X20500536.

肝臓科プロバイダーのトレーニングは、アルコール使用障害のスクリーニングとその結果としての介入を改善する

Training of hepatology providers improves the screening and resultant interventions for alcohol use disorder.
  • Hamzeh Saraireh
  • Joseph Redman
  • Thaer Abdelfattah
  • Sasha Mangray
  • James B Wade
  • HoChong S Gilles
  • Michael Fuchs
  • April Morris
  • Zenaida Malpaya
  • Puneet Puri
  • Brian C Davis
  • Samarth S Patel
  • Jasmohan S Bajaj
  • Liver Int..2020 Jul;doi: 10.1111/liv.14589.Epub 2020-07-07.

PD-L1発現率≧50%のNSCLC患者の大規模実世界コホートにおけるペムブロリズマブの免疫関連有害事象と臨床成績との関係

Immune-related Adverse Events of Pembrolizumab in a Large Real-world Cohort of Patients With NSCLC With a PD-L1 Expression ≥ 50% and Their Relationship With Clinical Outcomes.
  • Alessio Cortellini
  • Alex Friedlaender
  • Giuseppe L Banna
  • Giampiero Porzio
  • Melissa Bersanelli
  • Federico Cappuzzo
  • Joachim G J V Aerts
  • Raffaele Giusti
  • Emilio Bria
  • Diego Cortinovis
  • Francesco Grossi
  • Maria R Migliorino
  • Domenico Galetta
  • Francesco Passiglia
  • Rossana Berardi
  • Francesca Mazzoni
  • Vincenzo Di Noia
  • Diego Signorelli
  • Alessandro Tuzi
  • Alain Gelibter
  • Paolo Marchetti
  • Marianna Macerelli
  • Francesca Rastelli
  • Rita Chiari
  • Danilo Rocco
  • Alessandro Inno
  • Pietro Di Marino
  • Giovanni Mansueto
  • Federica Zoratto
  • Matteo Santoni
  • Marianna Tudini
  • Michele Ghidini
  • Marco Filetti
  • Annamaria Catino
  • Pamela Pizzutilo
  • Luca Sala
  • Mario Alberto Occhipinti
  • Fabrizio Citarella
  • Russano Marco
  • Mariangela Torniai
  • Luca Cantini
  • Alessandro Follador
  • Vincenzo Sforza
  • Olga Nigro
  • Miriam G Ferrara
  • Ettore D'Argento
  • Alessandro Leonetti
  • Linda Pettoruti
  • Lorenzo Antonuzzo
  • Simona Scodes
  • Lorenza Landi
  • Giorgia Guaitoli
  • Cinzia Baldessari
  • Federica Bertolini
  • Luigi Della Gravara
  • Maria Giovanna Dal Bello
  • Robert A Belderbos
  • Marco De Filippis
  • Cristina Cecchi
  • Serena Ricciardi
  • Clelia Donisi
  • Alessandro De Toma
  • Claudia Proto
  • Alfredo Addeo
  • Ornella Cantale
  • Biagio Ricciuti
  • Carlo Genova
  • Alessandro Morabito
  • Daniele Santini
  • Corrado Ficorella
  • Katia Cannita
  • Clin Lung Cancer.2020 Jun;S1525-7304(20)30204-7. doi: 10.1016/j.cllc.2020.06.010.Epub 2020-06-21.

フラクトース含有糖類の主要な食品供給源と罹患メタボリックシンドロームとの関連。システマティックレビューとメタアナリシス

Association of Major Food Sources of Fructose-Containing Sugars With Incident Metabolic Syndrome: A Systematic Review and Meta-analysis.
  • Zhila Semnani-Azad
  • Tauseef A Khan
  • Sonia Blanco Mejia
  • Russell J de Souza
  • Lawrence A Leiter
  • Cyril W C Kendall
  • Anthony J Hanley
  • John L Sievenpiper
  • JAMA Netw Open.2020 Jul;3(7):e209993. 2768092. doi: 10.1001/jamanetworkopen.2020.9993.Epub 2020-07-01.

一酸化窒素/cGMPシグナル伝達経路とカリウムチャネルがノトファギンの血圧降下作用に寄与していることを明らかにした

Nitric oxide/cGMP signaling pathway and potassium channels contribute to hypotensive effects of nothofagin.
  • Claudio H da Silva
  • Rhanany A Palozi
  • Priscila de Souza
  • Camila L de Almeida
  • Valdir Cechinel-Filho
  • Emerson L Lourenço
  • Arquimedes Gasparotto Junior
  • Minerva Cardioangiol.2020 Jul;S0026-4725.20.05243-3. doi: 10.23736/S0026-4725.20.05243-3.Epub 2020-07-10.

高リスク神経芽腫I-mIBG治療症例におけるより個別化医療のためのバイオドシメトリーツールとしての二心染色体アッセイの評価

Assessment of the dicentric chromosome assay as a biodosimetry tool for more personalized medicine in a case of a high risk neuroblastoma I-mIBG treatment.
  • Jose Maria Chimeno
  • Natividad Sebastià
  • Irene Torres-Espallardo
  • Julia Balaguer
  • Cristian Candela-Juan
  • Jose Luis Loaiza
  • Mar Adria
  • Blanca Ibanez-Rosello
  • Adela Cañete
  • Luis Martí-Bonmatí
  • Alegría Montoro
  • Int. J. Radiat. Biol..2019 03;95(3):314-320. doi: 10.1080/09553002.2019.1549755.Epub 2019-01-11.

硫黄マスタードの皮膚に対する病態生理学的効果と現在の治療法:ファイトケミカルの応用の可能性

Pathophysiological effects of sulfur mustard on skin and its current treatments: possible application of phytochemicals.
  • Mehdi Hassanpour
  • Fateme Hajihassani
  • Mina Abdollahpourasl
  • Omid Cheraghi
  • Nasser Aghamohamadzade
  • Reza Rahbargazi
  • Mohammad Nouri
  • Younes Pilehvar-Soltanahmadi
  • Nosratollah Zarghami
  • Abolfazl Akbarzadeh
  • Yunes Panahi
  • Amirhossein Sahebkar
  • Comb. Chem. High Throughput Screen..2020 Jul;CCHTS-EPUB-108233. doi: 10.2174/1386207323666200717150414.Epub 2020-07-17.

ペアハウジングでは、制御された強化剤の周波数手順を用いずに、アンフェタミンによって誘発されたリスキーな選択の変化に対する確率提示順序の変調効果を減衰させた

Pair housing, but not using a controlled reinforcer frequency procedure, attenuates the modulatory effect of probability presentation order on amphetamine-induced changes in risky choice.
  • Justin R Yates
  • Alexis L Ellis
  • Karson E Evans
  • Joy L Kappesser
  • Kadyn M Lilly
  • Prodiges Mbambu
  • Tanner G Sutphin
  • Behav. Brain Res..2020 Jul;390:112669. S0166-4328(20)30368-5. doi: 10.1016/j.bbr.2020.112669.Epub 2020-05-15.

非環状レチノイドとアンジオテンシンII受容体拮抗薬が糖尿病OLETFラットのジエチルニトロサミン誘発性肝癌化に対して複合的な保護効果を発揮する

Acyclic retinoid and angiotensin-II receptor blocker exert a combined protective effect against diethylnitrosamine-induced hepatocarcinogenesis in diabetic OLETF rats.
  • Norihisa Nishimura
  • Kosuke Kaji
  • Mitsuteru Kitade
  • Yosuke Aihara
  • Shinya Sato
  • Kenichiro Seki
  • Yasuhiko Sawada
  • Hiroaki Takaya
  • Yasushi Okura
  • Hideto Kawaratani
  • Kei Moriya
  • Tadashi Namisaki
  • Akira Mitoro
  • Hitoshi Yoshiji
  • BMC Cancer.2018 Nov;18(1):1164. 10.1186/s12885-018-5099-6. doi: 10.1186/s12885-018-5099-6.Epub 2018-11-26.

オペランド技術を用いて、高性能で安定なアルカリ膜燃料電池を理解し、設計することができます

Using operando techniques to understand and design high performance and stable alkaline membrane fuel cells.
  • Xiong Peng
  • Devashish Kulkarni
  • Ying Huang
  • Travis J Omasta
  • Benjamin Ng
  • Yiwei Zheng
  • Lianqin Wang
  • Jacob M LaManna
  • Daniel S Hussey
  • John R Varcoe
  • Iryna V Zenyuk
  • William E Mustain
  • Nat Commun.2020 Jul;11(1):3561. 10.1038/s41467-020-17370-7. doi: 10.1038/s41467-020-17370-7.Epub 2020-07-16.

ヘリコバクター・ピロリ除菌後の胃がんのリスク層別化.松島諸島における人口ベースの研究

Risk Stratification for Gastric Cancer after Helicobacter pylori Eradication: A Population-based Study on Matsu Islands.
  • Tsung-Hsien Chiang
  • Masahiro Maeda
  • Harumi Yamada
  • Chang-Chuan Chan
  • Sam Li-Sheng Chen
  • Sherry Yueh-Hsia Chiu
  • Yen-Nien Chen
  • Yi-Hsuan Chou
  • Chun-Fu Shieh
  • Cheng-Ying Liu
  • Han-Mo Chiu
  • Hung Chiang
  • Chia-Tung Shun
  • Ming-Wei Lin
  • Ming-Shiang Wu
  • Jaw-Town Lin
  • Chen Hsiu-Hsi
  • Toshikazu Ushijima
  • David Y Graham
  • Yi-Chia Lee
  • J. Gastroenterol. Hepatol..2020 Jul;doi: 10.1111/jgh.15187.Epub 2020-07-15.

サウジアラビアの女子大学の異なる医療従事者の学生を対象に、サウジアラビアのファーマコビジランス制度に関する意識、視点、基礎的な実践能力を比較評価した

The comparative assessment of awareness, perspective, and basic practice skills about the Saudi pharmacovigilance system among students of different health-care professionals of a Saudi Female University.
  • Asmatanzeem Bepari
  • Rasha Assad Assiri
  • Maya Abdullah AlYahya
  • Shaden Jamaan AlGhamdi
  • Amal Mohammed AlGhamdi
  • Afrah Asaad AlOnazi
  • Saudi Pharm J.2020 Jul;28(7):828-836. S1319-0164(20)30120-1. doi: 10.1016/j.jsps.2020.06.002.Epub 2020-06-12.

アンドロゲンジヒドロテストステロン(DHT)は、新たに同定された膜型アンドロゲン受容体(mAR-SLC39A9)を介してGαiタンパク質/MAPK/MMP9の細胞内シグナル伝達を介して、膀胱癌の核内AR陰性細胞浸潤を促進します

Androgen dihydrotestosterone (DHT) promotes the bladder cancer nuclear AR-negative cell invasion via a newly identified membrane androgen receptor (mAR-SLC39A9)-mediated Gαi protein/MAPK/MMP9 intracellular signaling.
  • Jinbo Chen
  • Fuju Chou
  • Shuyuan Yeh
  • Zhenyu Ou
  • Chihrong Shyr
  • Chiping Huang
  • Zhendong Xiang
  • Yin Sun
  • Edward Messing
  • Xiongbing Zu
  • Chawnshang Chang
  • Oncogene.2020 01;39(3):574-586. 10.1038/s41388-019-0964-6. doi: 10.1038/s41388-019-0964-6.Epub 2019-09-10.

パクリタキセル治療を受けた原発性皮膚血管肉腫患者を対象としたパゾパニブの単群確認試験。日本臨床腫瘍グループ試験(JCOG1605、JCOG-PCASプロトコール)

A single-arm confirmatory trial of pazopanib in patients with paclitaxel-pretreated primary cutaneous angiosarcoma: Japan Clinical Oncology Group study (JCOG1605, JCOG-PCAS protocol).
  • Kohei Oashi
  • Taro Shibata
  • Kenjiro Namikawa
  • Akira Takahashi
  • Kenji Yokota
  • Eiji Nakano
  • Yukiko Teramoto
  • Arata Tsutsumida
  • Taku Maeda
  • Naoya Yamazaki
  • BMC Cancer.2020 Jul;20(1):652. 10.1186/s12885-020-07136-1. doi: 10.1186/s12885-020-07136-1.Epub 2020-07-13.

網膜の健康と変性における小・中細胞外ベシクルとそのmiRNAカーゴ。網膜の恒常性維持のメディエーター、標的遺伝子治療のためのビークル

Small-Medium Extracellular Vesicles and Their miRNA Cargo in Retinal Health and Degeneration: Mediators of Homeostasis, and Vehicles for Targeted Gene Therapy.
  • Yvette Wooff
  • Adrian V Cioanca
  • Joshua A Chu-Tan
  • Riemke Aggio-Bruce
  • Ulrike Schumann
  • Riccardo Natoli
  • Front Cell Neurosci.2020;14:160. doi: 10.3389/fncel.2020.00160.Epub 2020-06-25.

コロンビアの和平合意から 1 年後の訓練と社会復帰のための領土空間における保健サービスへの効果的なアクセスの知覚:横断的研究

Perception of effective access to health services in Territorial Spaces for Training and Reintegration, one year after the peace accords in Colombia: a cross-sectional study.
  • Julián Alfredo Fernández-Niño
  • Lud Magdy Chavarro
  • Ana Beatriz Vásquez-Rodríguez
  • Maylen Liseth Rojas-Botero
  • Ginna Esmeralda Hernández-Neuta
  • Ana Maria Peñuela-Poveda
  • David Alejandro Rodríguez
  • F1000Res.2019;8:2140. doi: 10.12688/f1000research.21375.1.Epub 2019-12-23.

ウォルフ-パーキンソン-ホワイト症候群の小児患者におけるセプタル経路のスクリーニングに焦点を当てた付属経路局在化のための新しいアルゴリズム

New Algorithm for Accessory Pathway Localization Focused on Screening Septal Pathways in Pediatric Patients with Wolff-Parkinson-White Syndrome.
  • Seung Min Baek
  • Mi Kyoung Song
  • Jae-Sun Uhm
  • Gi Beom Kim
  • Eun Jung Bae
  • Heart Rhythm.2020 Jul;S1547-5271(20)30671-8. doi: 10.1016/j.hrthm.2020.07.016.Epub 2020-07-15.

天然アルカロイドであるベルベリンのピリジン誘導体をヒトのテロメリックG-DNAバインダーとして利用した研究」の訂正。溶液および固体状態の研究"を掲載しました

Correction to "Pyridine Derivative of the Natural Alkaloid Berberine as Human Telomeric G-DNA Binder: A Solution and Solid-State Study".
  • Francesco Papi
  • Carla Bazzicalupi
  • Marta Ferraroni
  • Giulia Ciolli
  • Paolo Lombardi
  • Asma Yasmeen Khan
  • Gopinatha Suresh Kumar
  • Paola Gratteri
  • ACS Med Chem Lett.2020 Jul;11(7):1490. doi: 10.1021/acsmedchemlett.0c00309.Epub 2020-06-22.

ブラックルクオリーブは、ラットの卵巣摘出術による骨量減少とタルク肉芽腫症を予防した

Black Lucques olives prevented bone loss caused by ovariectomy and talc granulomatosis in rats.
  • Caroline Puel
  • Julie Mardon
  • Séraphin Kati-Coulibaly
  • Marie-Jeanne Davicco
  • Patrice Lebecque
  • Christiane Obled
  • Edmond Rock
  • Marie-Noelle Horcajada
  • Apostolos Agalias
  • Leandros A Skaltsounis
  • Véronique Coxam
  • Br. J. Nutr..2007 May;97(5):1012-20. S0007114507659030. doi: 10.1017/S0007114507659030.

太陽の下でのストレス。海産二枚貝のフィルターフィーダーであるマニラアサリのRuditapes philippinarumにおける低濃度UVフィルター4-メチルベンジリデンカンファー(4-MBC)への曝露の影響

Stress under the sun: Effects of exposure to low concentrations of UV-filter 4- methylbenzylidene camphor (4-MBC) in a marine bivalve filter feeder, the Manila clam Ruditapes philippinarum.
  • Melania Santonocito
  • Barbara Salerno
  • Chiara Trombini
  • Federico Tonini
  • Marina G Pintado-Herrera
  • Gonzálo Martínez-Rodríguez
  • Julián Blasco
  • Pablo Antonio Lara-Martín
  • Miriam Hampel
  • Aquat. Toxicol..2020 Apr;221:105418. S0166-445X(19)30894-X. doi: 10.1016/j.aquatox.2020.105418.Epub 2020-02-03.

コンゴ民主共和国のマランガ(キンペーゼ)睡眠病フォーカスのツェツェバエの中腸における異なるトリパノソーマ種の同定

Identification of different trypanosome species in the mid-guts of tsetse flies of the Malanga (Kimpese) sleeping sickness focus of the Democratic Republic of Congo.
  • Gustave Simo
  • Barberine Silatsa
  • Njiokou Flobert
  • Pascal Lutumba
  • Philemon Mansinsa
  • Joule Madinga
  • Emile Manzambi
  • Reginald De Deken
  • Tazoacha Asonganyi
  • Parasit Vectors.2012 Sep;5:201. 1756-3305-5-201. doi: 10.1186/1756-3305-5-201.Epub 2012-09-19.

抗線溶性部位特異的ファーマコレーザー治療によるポートワインの汚れの治療のための熱感受性リポソームのインビボ評価

In Vivo Assessment of Thermosensitive Liposomes for the Treatment of Port Wine Stains by Antifibrinolytic Site-Specific Pharmaco-Laser Therapy.
  • Mingjuan Li
  • M Ingmar van Raath
  • Shervin Khakpour
  • Ahmet Seçilir
  • Bart C Sliggers
  • Xuan Huang
  • Baoyue Ding
  • Gert Storm
  • René R van der Hulst
  • Anton I P M de Kroon
  • Michal Heger
  • Pharmaceutics.2020 Jun;12(6). E591. doi: 10.3390/pharmaceutics12060591.Epub 2020-06-25.

硝酸ナトリウム処理ラットにおけるJ.carnae葉抽出物の血球保護作用および赤血球膜安定化作用

Haematoprotective and red blood cell membrane stabilizing effects of Justicia carnae leaf extracts in sodium nitrate-treated rats.
  • Eberechukwu Mbanaso
  • Azubuike Nwankwo
  • Solomon Nnah Ijioma
  • Okezie Emmanuel
  • Eziuche Amadike Ugbogu
  • Ngozi Nwagbara
  • Kingsley Ugwuanyi
  • J Basic Clin Physiol Pharmacol.2020 Jul;/j/jbcpp.ahead-of-print/jbcpp-2019-0275/jbcpp-2019-0275.xml. doi: 10.1515/jbcpp-2019-0275.Epub 2020-07-13.

ヒトコレクトリン-11(COLEC11)とそのMASP2との相乗的な遺伝的相互作用は、シャーガス病の病態生理に関連しています

Human collectin-11 (COLEC11) and its synergic genetic interaction with MASP2 are associated with the pathophysiology of Chagas Disease.
  • Thaisa Lucas Sandri
  • Fabiana Antunes Andrade
  • Kárita Cláudia Freitas Lidani
  • Elias Einig
  • Angelica Beate Winter Boldt
  • Benjamin Mordmüller
  • Meral Esen
  • Iara J Messias-Reason
  • PLoS Negl Trop Dis.2019 04;13(4):e0007324. PNTD-D-18-01714. doi: 10.1371/journal.pntd.0007324.Epub 2019-04-17.

黒胡椒由来のアルカロイドはNF-κB経路の活性化を阻害することにより、マウスマクロファージにおける抗炎症活性を示します

Alkaloids from Black Pepper ( L.) Exhibit Anti-Inflammatory Activity in Murine Macrophages by Inhibiting Activation of NF-κB Pathway.
  • Heying Pei
  • Linlin Xue
  • Minghai Tang
  • Huan Tang
  • Shuang Kuang
  • Lun Wang
  • Xu Ma
  • Xiaoying Cai
  • Yan Li
  • Min Zhao
  • Aihua Peng
  • Haoyu Ye
  • Lijuan Chen
  • J. Agric. Food Chem..2020 Feb;68(8):2406-2417. doi: 10.1021/acs.jafc.9b07754.Epub 2020-02-18.

一半球の可塑性、二半球からの制御:新生児ラットの片側皮質脊髄損傷後の下降運動経路の適応性

Plasticity in One Hemisphere, Control From Two: Adaptation in Descending Motor Pathways After Unilateral Corticospinal Injury in Neonatal Rats.
  • Tong-Chun Wen
  • Sophia Lall
  • Corey Pagnotta
  • James Markward
  • Disha Gupta
  • Shivakeshavan Ratnadurai-Giridharan
  • Jacqueline Bucci
  • Lucy Greenwald
  • Madelyn Klugman
  • N Jeremy Hill
  • Jason B Carmel
  • Front Neural Circuits.2018;12:28. doi: 10.3389/fncir.2018.00028.Epub 2018-04-12.

サフィナミドの覚醒剤誘発性神経変性に対する神経保護作用と神経生存能。BDNF/TrkB/PGC-1αシグナル伝達経路とミトコンドリアアンカップリングプロテイン-2(UCP-2)の役割の仮説的可能性

Neuroprotective and neuro-survival properties of safinamide against methamphetamine-induced neurodegeneration: Hypothetic possible role of BDNF/TrkB/PGC-1α signaling pathway and mitochondrial uncoupling protein -2(UCP-2).
  • Afrah Sepehr
  • Fereshteh Taheri
  • Sara Heidarian
  • Majid Motaghinejad
  • Sepideh Safari
  • Med. Hypotheses.2020 Jul;143:110094. S0306-9877(20)30442-4. doi: 10.1016/j.mehy.2020.110094.Epub 2020-07-11.

甲状腺転写因子1(TTF-1)陰性、EGFR/ALK陰性の肺腺がんにおけるペメトレキセドベースの化学療法は、ペメトレキセドを含まないレジメンよりも劣る:傾向スコアマッチドペア分析

Pemetrexed-Based Chemotherapy Is Inferior to Pemetrexed-Free Regimens in Thyroid Transcription Factor 1 (TTF-1)-Negative, EGFR/ALK-Negative Lung Adenocarcinoma: A Propensity Score Matched Pairs Analysis.
  • Nikolaj Frost
  • Tamar Zhamurashvili
  • Maximilian von Laffert
  • Frederick Klauschen
  • Christoph Ruwwe-Glösenkamp
  • Matthias Raspe
  • Matthias Brunn
  • Sebastian Ochsenreither
  • Bettina Temmesfeld-Wollbrück
  • Norbert Suttorp
  • Christian Grohé
  • Martin Witzenrath
  • Clin Lung Cancer.2020 May;S1525-7304(20)30154-6. doi: 10.1016/j.cllc.2020.05.014.Epub 2020-05-22.

ミクログリアの活性化を調節することで、歯状回におけるアルギナーゼ1を介した母体免疫活性化による統合失調症関連行動の表現型を防ぐことができる

Modulating microglia activation prevents maternal immune activation induced schizophrenia-relevant behavior phenotypes via arginase 1 in the dentate gyrus.
  • Yucen Xia
  • Zhiqing Zhang
  • Weipeng Lin
  • Jinglan Yan
  • Chuan'an Zhu
  • Dongmin Yin
  • Su He
  • Yang Su
  • Nenggui Xu
  • Robert William Caldwell
  • Lin Yao
  • Yongjun Chen
  • Neuropsychopharmacology.2020 Jun;10.1038/s41386-020-0743-7. doi: 10.1038/s41386-020-0743-7.Epub 2020-06-29.

インド・ベンガルールの農村と都市の界面における野縁植生の構造と構成:農業生態系の未踏の側面に関する事例研究

Structure and composition of field margin vegetation in the rural-urban interface of Bengaluru, India: a case study on an unexplored dimension of agroecosystems.
  • Sunil Nautiyal
  • Mrinalini Goswami
  • Rama Rao Nidamanuri
  • Ellen M Hoffmann
  • Andreas Buerkert
  • Environ Monit Assess.2020 Jul;192(8):520. 10.1007/s10661-020-08428-6. doi: 10.1007/s10661-020-08428-6.Epub 2020-07-15.