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日本語AIでPubMedを検索

日本語AIでPubMedを検索

PubMedの提供する医学論文データベースを日本語で検索できます。AI(Deep Learning)を活用した機械翻訳エンジンにより、精度高く日本語へ翻訳された論文をご参照いただけます。

みんなが読んでいる論文

Radix BupleuriとRadix Paeoniae Albaの抗うつ効果とメカニズムを探る統合的メタボロミクスとネットワーク薬理学的手法

An integrative metabolomics and network pharmacology method for exploring the effect and mechanism of Radix Bupleuri and Radix Paeoniae Alba on anti-depression.
  • Hongcai Zhang
  • Shuxiang Zhang
  • Mingxu Hu
  • Yanyan Chen
  • Wenran Wang
  • Ke Zhang
  • Haixue Kuang
  • Qiuhong Wang
  • J Pharm Biomed Anal.2020 Jul;189:113435. S0731-7085(20)31321-2. doi: 10.1016/j.jpba.2020.113435.Epub 2020-07-02.

胎児臍帯動脈の脈動性は、先天性心疾患の2年間の成長と神経発達の成果と相関しています

Fetal Umbilical Arterial Pulsatility Correlates With 2-Year Growth and Neurodevelopmental Outcomes in Congenital Heart Disease.
  • Jayani B Abeysekera
  • Dora L Gyenes
  • Joseph Atallah
  • Charlene M T Robertson
  • Gwen Y Bond
  • Ivan M Rebeyka
  • Elham Khodayari Moez
  • Irina A Dinu
  • Heather N Switzer
  • Lisa K Hornberger
  • Can J Cardiol.2020 Jul;S0828-282X(20)30588-2. doi: 10.1016/j.cjca.2020.06.024.Epub 2020-07-09.

本研究では、UPLC-Q/TOF-MSメタボロミクスを用いて、薬用植物Phellodendri Amurensis cortexのドキソルビシン誘発性腎炎ラットに対する作用機序の解明に向けて、代謝物と代謝経路の変化を明らかにしました

Characterizing metabolites and potential metabolic pathways changes to understanding the mechanism of medicinal plant Phellodendri Amurensis cortex against doxorubicin-induced nephritis rats using UPLC-Q/TOF-MS metabolomics.
  • Hongcai Zhang
  • Shuxiang Zhang
  • Wenran Wang
  • Qi Wang
  • Haixue Kuang
  • Qiuhong Wang
  • J Pharm Biomed Anal.2020 May;188:113336. S0731-7085(20)30634-8. doi: 10.1016/j.jpba.2020.113336.Epub 2020-05-22.

エルロチニブの非小細胞肺がんに対する中隔膜転移を有する非小細胞肺がんの治療薬。第II相試験(LOGIK1101)

Erlotinib for Non-Small Cell Lung Cancer with Leptomeningeal Metastases: A Phase II Study (LOGIK1101).
  • Kaname Nosaki
  • Takeharu Yamanaka
  • Akinobu Hamada
  • Yoshimasa Shiraishi
  • Taishi Harada
  • Daisuke Himeji
  • Takeshi Kitazaki
  • Noriyuki Ebi
  • Takayuki Shimose
  • Takashi Seto
  • Mitsuhiro Takenoyama
  • Kenji Sugio
  • Oncologist.2020 Jul;doi: 10.1634/theoncologist.2020-0640.Epub 2020-07-12.

ラット坐骨神経損傷モデルにおける脂肪組織由来幹細胞と血小板リッチフィブリン再遊離液の再生可能性

Regenerative Potential of Platelet-Rich Fibrin Releasate Combined with Adipose Tissue-Derived Stem Cells in a Rat Sciatic Nerve Injury Model.
  • Ming-Hsi Chuang
  • Li-Hsing Ho
  • Tzong-Fu Kuo
  • Shi-Yuan Sheu
  • Yu-Hao Liu
  • Po-Cheng Lin
  • Yu-Chen Tsai
  • Chang-Huan Yang
  • Chi-Ming Chu
  • Shinn-Zong Lin
  • Cell Transplant.2020 Jan-Dec;29:963689720919438. doi: 10.1177/0963689720919438.

ペルー・アマゾンの中新世後期中新世からのネオサイミリ(Cebidae, Platyrrhini)の新記録

New record of Neosaimiri (Cebidae, Platyrrhini) from the late Middle Miocene of Peruvian Amazonia.
  • Laurent Marivaux
  • Walter Aguirre-Diaz
  • Aldo Benites-Palomino
  • Guillaume Billet
  • Myriam Boivin
  • François Pujos
  • Rodolfo Salas-Gismondi
  • Julia V Tejada-Lara
  • Rafael M Varas-Malca
  • Pierre-Olivier Antoine
  • J. Hum. Evol..2020 Jul;146:102835. S0047-2484(20)30096-8. doi: 10.1016/j.jhevol.2020.102835.Epub 2020-07-08.

PTPN2はマクロファージと腸管上皮細胞の相互作用を制御し、腸管バリア機能を促進する

PTPN2 Regulates Interactions Between Macrophages and Intestinal Epithelial Cells to Promote Intestinal Barrier Function.
  • Marianne R Spalinger
  • Anica Sayoc-Becerra
  • Alina N Santos
  • Ali Shawki
  • Vinicius Canale
  • Moorthy Krishnan
  • Anna Niechcial
  • Nicole Obialo
  • Michael Scharl
  • Jiang Li
  • Meera G Nair
  • Declan F McCole
  • Gastroenterology.2020 Jul;S0016-5085(20)34922-2. doi: 10.1053/j.gastro.2020.07.004.Epub 2020-07-08.

冬期の北中国平原の典型的な農村地域における大気カルボニルの汚染レベル、変動特性、発生源、環境への影響を調査した

The pollution levels, variation characteristics, sources and implications of atmospheric carbonyls in a typical rural area of North China Plain during winter.
  • Jinhe Wang
  • Shuyu Sun
  • Chongxu Zhang
  • Chaoyang Xue
  • Pengfei Liu
  • Chenglong Zhang
  • Yujing Mu
  • Hai Wu
  • Defa Wang
  • Hui Chen
  • Jianmin Chen
  • J Environ Sci (China).2020 Sep;95:256-265. S1001-0742(20)30198-4. doi: 10.1016/j.jes.2020.05.003.Epub 2020-06-28.

Streptomyces cattleya由来チエナマイシン遺伝子クラスター内のチエナマイシンおよびセファマイシンC生合成遺伝子の転写活性化因子の同定

Identification of transcriptional activators for thienamycin and cephamycin C biosynthetic genes within the thienamycin gene cluster from Streptomyces cattleya.
  • Miriam Rodríguez
  • Luz Elena Núñez
  • Alfredo F Braña
  • Carmen Méndez
  • José A Salas
  • Gloria Blanco
  • Mol. Microbiol..2008 Aug;69(3):633-45. MMI6312. doi: 10.1111/j.1365-2958.2008.06312.x.

ファイバー補強コンポジット製ポストアンドコア修復物の破損に及ぼすフェルール効果の影響.システマティックレビューとメタアナリシス

Influence of the ferrule effect on the failure of fiber-reinforced composite post-and-core restorations: A systematic review and meta-analysis.
  • Victor Eduardo de Souza Batista
  • Sandro Basso Bitencourt
  • Natália Almeida Bastos
  • Eduardo Piza Pellizzer
  • Marcelo Coelho Goiato
  • Daniela Micheline Dos Santos
  • J Prosthet Dent.2020 Feb;123(2):239-245. S0022-3913(19)30079-4. doi: 10.1016/j.prosdent.2019.01.004.Epub 2019-06-18.

フランス人集団における骨欠損症管理のための骨移植片、骨代替品、再生医療の受容。倫理、宗教、恐怖の問題?

Bone Grafts, Bone Substitutes and Regenerative Medicine Acceptance for the Management of Bone Defects Among French Population: Issues about Ethics, Religion or Fear?
  • Damien Offner
  • Gabriel Fernandez de Grado
  • Inès Meisels
  • Luc Pijnenburg
  • Florence Fioretti
  • Nadia Benkirane-Jessel
  • Anne-Marie Musset
  • Cell Med.2019;11:2155179019857661. 10.1177_2155179019857661. doi: 10.1177/2155179019857661.Epub 2019-06-20.

RIFM香料成分安全性評価、アントラニル酸β-ナフチル、CAS登録番号63449-68-3

RIFM fragrance ingredient safety assessment, β-naphthyl anthranilate, CAS Registry Number 63449-68-3.
  • A M Api
  • F Belmonte
  • D Belsito
  • S Biserta
  • D Botelho
  • M Bruze
  • G A Burton
  • J Buschmann
  • M A Cancellieri
  • M L Dagli
  • M Date
  • W Dekant
  • C Deodhar
  • A D Fryer
  • S Gadhia
  • L Jones
  • K Joshi
  • A Lapczynski
  • M Lavelle
  • D C Liebler
  • M Na
  • D O'Brien
  • A Patel
  • T M Penning
  • G Ritacco
  • F Rodriguez-Ropero
  • J Romine
  • N Sadekar
  • D Salvito
  • T W Schultz
  • F Siddiqi
  • I G Sipes
  • G Sullivan
  • Y Thakkar
  • Y Tokura
  • S Tsang
  • Food Chem. Toxicol..2020 Jul;:111531. S0278-6915(20)30421-X. doi: 10.1016/j.fct.2020.111531.Epub 2020-07-05.

高リン酸血症に対する鉄系リン酸塩バインダーであるPT20の有効性と安全性:血液透析依存性慢性腎臓病患者を対象とした無作為化二重盲検プラセボ対照用量漸増第IIb相試験

Efficacy and safety of PT20, an iron-based phosphate binder, for the treatment of hyperphosphataemia: a randomized, double-blind, placebo-controlled, dose-ranging, Phase IIb study in patients with haemodialysis-dependent chronic kidney disease.
  • Mark Sampson
  • Nuno Faria
  • Jonathan J Powell
  • Nephrol. Dial. Transplant..2020 Jul;gfaa116. doi: 10.1093/ndt/gfaa116.Epub 2020-07-11.

縦断的血漿プロテオームプロファイリングから決定された個人特有の健康状態の特徴

Facets of individual-specific health signatures determined from longitudinal plasma proteome profiling.
  • Tea Dodig-Crnković
  • Mun-Gwan Hong
  • Cecilia Engel Thomas
  • Ragna S Häussler
  • Annika Bendes
  • Matilda Dale
  • Fredrik Edfors
  • Björn Forsström
  • Patrik K E Magnusson
  • Ina Schuppe-Koistinen
  • Jacob Odeberg
  • Linn Fagerberg
  • Anders Gummesson
  • Göran Bergström
  • Mathias Uhlén
  • Jochen M Schwenk
  • EBioMedicine.2020 Jul;57:102854. S2352-3964(20)30229-2. doi: 10.1016/j.ebiom.2020.102854.Epub 2020-07-03.

株DP-Dzr46)由来の食品酵素グルカン1,4-α-マルトテトラオヒドロラーゼの安全性評価

Safety evaluation of the food enzyme glucan 1,4-α-maltotetraohydrolase from (strain DP-Dzr46).
  • Vittorio Silano
  • José Manuel Barat Baviera
  • Claudia Bolognesi
  • Beat Johannes Brüschweiler
  • Pier Sandro Cocconcelli
  • Riccardo Crebelli
  • David Michael Gott
  • Konrad Grob
  • Evgenia Lampi
  • Alicja Mortensen
  • Gilles Rivière
  • Inger-Lise Steffensen
  • Christina Tlustos
  • Henk Van Loveren
  • Laurence Vernis
  • Holger Zorn
  • Boet Glandorf
  • Lieve Herman
  • Karl-Heinz Engel
  • Sirpa Kärenlampi
  • Francesca Marcon
  • André Penninks
  • Jaime Aguilera
  • Margarita Aguilera-Gómez
  • Natalia Kovalkovicova
  • Yi Liu
  • Joaquim Maia
  • Sandra Rainieri
  • Andrew Chesson
  • EFSA J.2019 May;17(5):e05684. EFS25684. doi: 10.2903/j.efsa.2019.5684.Epub 2019-05-08.

生物学的経験のある乾癬性関節炎患者におけるセスキヌマブの実際の有効性と安全性

Real Life Efficacy and Safety of Secukinumab in Biologic-Experienced Patients With Psoriatic Arthritis.
  • Kalliopi Klavdianou
  • Argyro Lazarini
  • Alexandros Grivas
  • Dimitrios Tseronis
  • Christina Tsalapaki
  • Panagiota Rapsomaniki
  • Katerina Antonatou
  • Konstantinos Thomas
  • Dimitrios Boumpas
  • Pelagia Katsimbri
  • Dimitrios Vassilopoulos
  • Front Med (Lausanne).2020;7:288. doi: 10.3389/fmed.2020.00288.Epub 2020-06-19.

クロトンウルクラナ・バイヨン幹樹皮軟膏は、IL-10ノックアウトマウスの皮膚創傷の閉鎖を促進した

Croton urucurana Baillon stem bark ointment accelerates the closure of cutaneous wounds in knockout IL-10 mice.
  • Thalia Del Rosario Loyo Casao
  • Camila Graça Pinheiro
  • Mariáurea Matias Sarandy
  • Ana Caroline Zanatta
  • Wagner Vilegas
  • Rômulo Dias Novaes
  • Reggiani Vilela Gonçalves
  • João Paulo Viana Leite
  • J Ethnopharmacol.2020 Jun;261:113042. S0378-8741(19)32256-1. doi: 10.1016/j.jep.2020.113042.Epub 2020-06-10.

ドイツにおける再発・難治性多発性骨髄腫の治療における経口および静脈内治療レジメンの使用に関する予算インパクト分析

Budget impact analysis of the use of oral and intravenous therapy regimens for the treatment of relapsed or refractory multiple myeloma in Germany.
  • Edin Basic
  • Mathias Kappel
  • Arpit Misra
  • Leopold Sellner
  • Boris A Ratsch
  • Dennis A Ostwald
  • Eur J Health Econ.2020 Jul;10.1007/s10198-020-01219-3. doi: 10.1007/s10198-020-01219-3.Epub 2020-07-11.

SARS-CoV-2ゲノムシークエンシングとエージェントベースのモデリングにより、オーストラリアにおけるCOVID-19感染を明らかにする

Revealing COVID-19 transmission in Australia by SARS-CoV-2 genome sequencing and agent-based modeling.
  • Rebecca J Rockett
  • Alicia Arnott
  • Connie Lam
  • Rosemarie Sadsad
  • Verlaine Timms
  • Karen-Ann Gray
  • John-Sebastian Eden
  • Sheryl Chang
  • Mailie Gall
  • Jenny Draper
  • Eby M Sim
  • Nathan L Bachmann
  • Ian Carter
  • Kerri Basile
  • Roy Byun
  • Matthew V O'Sullivan
  • Sharon C-A Chen
  • Susan Maddocks
  • Tania C Sorrell
  • Dominic E Dwyer
  • Edward C Holmes
  • Jen Kok
  • Mikhail Prokopenko
  • Vitali Sintchenko
  • Nat. Med..2020 Jul;10.1038/s41591-020-1000-7. doi: 10.1038/s41591-020-1000-7.Epub 2020-07-09.